JP2024532957A - ウデナフィル組成物を用いた線維肝状態を処置する方法および組成物 - Google Patents

ウデナフィル組成物を用いた線維肝状態を処置する方法および組成物 Download PDF

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Publication number
JP2024532957A
JP2024532957A JP2024533929A JP2024533929A JP2024532957A JP 2024532957 A JP2024532957 A JP 2024532957A JP 2024533929 A JP2024533929 A JP 2024533929A JP 2024533929 A JP2024533929 A JP 2024533929A JP 2024532957 A JP2024532957 A JP 2024532957A
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Prior art keywords
liver
patient
fibrosis
elf
score
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JP2024533929A
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Japanese (ja)
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JP2024532957A5 (https=
Inventor
ゴールドバーグ，デビッド，ジェイ．
ラッセル，マーク，ダブリュ．
シューマッハ，クルト，アール．
イェーガー，ジェームズ，エル．
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Publication of JP2024532957A publication Critical patent/JP2024532957A/ja
Publication of JP2024532957A5 publication Critical patent/JP2024532957A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2024533929A 2021-08-13 2022-08-12 ウデナフィル組成物を用いた線維肝状態を処置する方法および組成物 Pending JP2024532957A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163233133P 2021-08-13 2021-08-13
US63/233,133 2021-08-13
PCT/US2022/040227 WO2023018972A1 (en) 2021-08-13 2022-08-12 Methods and compositions for treating fibrotic liver conditions, using udenafil compositions

Publications (2)

Publication Number Publication Date
JP2024532957A true JP2024532957A (ja) 2024-09-10
JP2024532957A5 JP2024532957A5 (https=) 2025-08-19

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ID=83355014

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JP2024533929A Pending JP2024532957A (ja) 2021-08-13 2022-08-12 ウデナフィル組成物を用いた線維肝状態を処置する方法および組成物

Country Status (7)

Country Link
US (2) US20230218622A1 (https=)
EP (1) EP4384176A1 (https=)
JP (1) JP2024532957A (https=)
AU (1) AU2022325803A1 (https=)
CA (1) CA3229274A1 (https=)
MX (1) MX2024001972A (https=)
WO (1) WO2023018972A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12396708B2 (en) * 2024-01-08 2025-08-26 Echosens Sa Method for determining an index for assessing a cardiac function of a subject
EP4582017A1 (en) * 2024-01-08 2025-07-09 Echosens Method for determining an index for assessing a cardiac function of a subject

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0202254D0 (en) * 2002-01-31 2002-03-20 Pfizer Ltd Prevention of scarring
PT1888074E (pt) * 2005-06-10 2012-03-01 Dong A Pharm Co Ltd Agente para a prevenção e tratamento de doenças do fígado contendo um derivado de pirazolopirimidina
TN2017000029A1 (en) 2014-08-12 2018-07-04 Mezzion Pharma Co Ltd Methods of improving myocardial performance in fontan patients using udenafil compositions

Also Published As

Publication number Publication date
AU2022325803A1 (en) 2024-03-28
EP4384176A1 (en) 2024-06-19
WO2023018972A1 (en) 2023-02-16
US20250186448A1 (en) 2025-06-12
US20230218622A1 (en) 2023-07-13
CA3229274A1 (en) 2023-02-16
MX2024001972A (es) 2024-11-08

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