JP2024529291A - ウイルス感染症の処置および予防のための組成物および方法 - Google Patents

ウイルス感染症の処置および予防のための組成物および方法 Download PDF

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JP2024529291A
JP2024529291A JP2024500046A JP2024500046A JP2024529291A JP 2024529291 A JP2024529291 A JP 2024529291A JP 2024500046 A JP2024500046 A JP 2024500046A JP 2024500046 A JP2024500046 A JP 2024500046A JP 2024529291 A JP2024529291 A JP 2024529291A
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JP2024529291A5 (https=
JPWO2023283586A5 (https=
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ラルフ エー． トリップ，
ジャクリーン マレイ，
デビ カリヤン カルーマンチ，
デイビッド ユージーン マーティン，
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ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/035—Organic compounds containing oxygen as heteroatom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/045—Organic compounds containing nitrogen as heteroatom
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/03—Organic compounds
    • A23L29/055—Organic compounds containing sulfur as heteroatom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/02—Monocyclic hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)
JP2024500046A 2021-07-06 2022-07-06 ウイルス感染症の処置および予防のための組成物および方法 Pending JP2024529291A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163203026P 2021-07-06 2021-07-06
US63/203,026 2021-07-06
US202263349364P 2022-06-06 2022-06-06
US63/349,364 2022-06-06
PCT/US2022/073476 WO2023283586A2 (en) 2021-07-06 2022-07-06 Compositions and methods for treating and preventing viral infections

Publications (3)

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JP2024529291A true JP2024529291A (ja) 2024-08-06
JP2024529291A5 JP2024529291A5 (https=) 2025-07-11
JPWO2023283586A5 JPWO2023283586A5 (https=) 2025-07-11

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JP2024500046A Pending JP2024529291A (ja) 2021-07-06 2022-07-06 ウイルス感染症の処置および予防のための組成物および方法

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US (1) US20240327339A1 (https=)
EP (1) EP4367086A4 (https=)
JP (1) JP2024529291A (https=)
AU (1) AU2022309236A1 (https=)
CA (1) CA3224519A1 (https=)
WO (1) WO2023283586A2 (https=)

Families Citing this family (1)

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Publication number Priority date Publication date Assignee Title
CN117100743B (zh) * 2023-08-21 2026-03-31 海南大学 一种倍半萜内酯类化合物在制备抗病毒药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597198A (ja) * 1982-06-16 1984-01-14 ビ−チヤム・グル−プ・ピ−エルシ− ２′−デオキシウリジン化合物、その製造方法及びそれを有する製薬組成物
WO2000006581A1 (en) * 1998-07-27 2000-02-10 Meiji Seika Kaisha, Ltd. Novel carbapenem derivatives
CN106470981B (zh) * 2014-06-23 2019-05-07 湘北威尔曼制药股份有限公司 2-[3-氰基-4-异丁氧基苯基]-4-甲基噻唑-5-甲酸的新型衍生物、其制备方法和应用
JP7840570B2 (ja) * 2020-04-10 2026-04-06 ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド コロナウイルス感染症の処置のための方法

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WO2004099127A1 (en) * 2003-05-07 2004-11-18 Novo Nordisk A/S Novel compounds as kinase inhibitors
WO2012142492A2 (en) * 2011-04-15 2012-10-18 University Of Georgia Research Foundation, Inc. Methods for inhibiting virus replication
RU2014121984A (ru) * 2011-10-31 2015-12-10 Ксенон Фармасьютикалз Инк. Бензолсульфонамидные соединения и их применение в качестве терапевтических средств
WO2016017826A1 (ja) * 2014-07-30 2016-02-04 帝人ファーマ株式会社 キサンチンオキシダーゼ阻害薬
JP7640458B2 (ja) * 2018-10-05 2025-03-05 アンナプルナ バイオ インコーポレイテッド Ａｐｊ受容体活性に関連する状態を処置するための化合物および組成物
US11116737B1 (en) * 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597198A (ja) * 1982-06-16 1984-01-14 ビ−チヤム・グル−プ・ピ−エルシ− ２′−デオキシウリジン化合物、その製造方法及びそれを有する製薬組成物
WO2000006581A1 (en) * 1998-07-27 2000-02-10 Meiji Seika Kaisha, Ltd. Novel carbapenem derivatives
CN106470981B (zh) * 2014-06-23 2019-05-07 湘北威尔曼制药股份有限公司 2-[3-氰基-4-异丁氧基苯基]-4-甲基噻唑-5-甲酸的新型衍生物、其制备方法和应用
JP7840570B2 (ja) * 2020-04-10 2026-04-06 ユニバーシティ・オブ・ジョージア・リサーチ・ファウンデイション・インコーポレイテッド コロナウイルス感染症の処置のための方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAYTON, PETER G.: "The Metabolism of Probenecid in Man", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, vol. 179, JPN6026014189, 1 July 1971 (1971-07-01), pages 399 - 402, ISSN: 0005837528 *
PERWITASARI, OLIVIA: "Targeting Organic Anion Transporter 3 with Probenecid as a Novel Anti-Influenza A Virus Strategy", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 57, no. 1, JPN6026014190, 2013, pages 475 - 483, ISSN: 0005837529 *

Also Published As

Publication number Publication date
AU2022309236A9 (en) 2024-02-22
EP4367086A4 (en) 2025-06-25
WO2023283586A3 (en) 2023-02-16
CA3224519A1 (en) 2023-01-12
US20240327339A1 (en) 2024-10-03
AU2022309236A1 (en) 2024-01-25
WO2023283586A2 (en) 2023-01-12
EP4367086A2 (en) 2024-05-15

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