JP2024525612A5 - - Google Patents

Info

Publication number
JP2024525612A5
JP2024525612A5 JP2024500480A JP2024500480A JP2024525612A5 JP 2024525612 A5 JP2024525612 A5 JP 2024525612A5 JP 2024500480 A JP2024500480 A JP 2024500480A JP 2024500480 A JP2024500480 A JP 2024500480A JP 2024525612 A5 JP2024525612 A5 JP 2024525612A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide
optionally
complex according
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500480A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525612A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073534 external-priority patent/WO2023283619A2/en
Publication of JP2024525612A publication Critical patent/JP2024525612A/ja
Publication of JP2024525612A5 publication Critical patent/JP2024525612A5/ja
Pending legal-status Critical Current

Links

JP2024500480A 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用 Pending JP2024525612A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163220030P 2021-07-09 2021-07-09
US63/220,030 2021-07-09
PCT/US2022/073534 WO2023283619A2 (en) 2021-07-09 2022-07-08 Muscle targeting complexes and uses thereof for treating dystrophinopathies

Publications (2)

Publication Number Publication Date
JP2024525612A JP2024525612A (ja) 2024-07-12
JP2024525612A5 true JP2024525612A5 (enExample) 2025-07-17

Family

ID=84802094

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500480A Pending JP2024525612A (ja) 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用

Country Status (8)

Country Link
US (1) US20240382609A1 (enExample)
EP (1) EP4367142A4 (enExample)
JP (1) JP2024525612A (enExample)
KR (1) KR20240032946A (enExample)
CN (1) CN118401553A (enExample)
CA (1) CA3226300A1 (enExample)
IL (1) IL309911A (enExample)
WO (1) WO2023283619A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3108282A1 (en) 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
SG11202100928QA (en) 2018-08-02 2021-02-25 Dyne Therapeutics Inc Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
JP2024525608A (ja) 2021-07-09 2024-07-12 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体および製剤
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
IL316143A (en) 2022-04-15 2024-12-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2639852T3 (es) * 2007-10-26 2017-10-30 Academisch Ziekenhuis Leiden Medios y métodos para contrarrestar los trastornos musculares
CA3108282A1 (en) * 2018-08-02 2020-02-06 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL312067B2 (en) * 2018-12-21 2025-08-01 Avidity Biosciences Inc Anti-transferrin receptor antibodies and uses thereof
MX2023000984A (es) * 2020-07-23 2023-05-03 Dyne Therapeutics Inc Complejos dirigidos al musculo y usos de los mismos para el tratamiento de distrofinopatias.

Similar Documents

Publication Publication Date Title
JP2024525612A5 (enExample)
JP2024525611A5 (enExample)
JP2024525613A5 (enExample)
JP2024527362A5 (enExample)
JP2024525610A5 (enExample)
IL309937A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309911A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309935A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309912A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309909A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
JP2023510350A5 (enExample)
US11771776B2 (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
JP2023535073A5 (enExample)
US20230088865A1 (en) Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US20240117356A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20240216522A1 (en) Muscle targeting complexes and uses thereof for treating friedreich's ataxia
IL309936A (en) Muscle targeting complexes and formulations for the treatment of dystrophinopathy
CA3226301A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
JP2024540199A (ja) ジストロフィノパチーを処置するための筋標的化複合体
US20240398968A1 (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
JP2026503873A (ja) Dmd遺伝子のエクソン45をスキップするための筋肉標的化複合体およびその使用
JP2024524222A5 (enExample)
JP2024540199A5 (enExample)
IL316206A (en) Dosage of muscle targeting complexes for the treatment of myotonic dystrophy
IL322946A (en) Methods and compositions for inhibiting the progression of intramuscular fibrosis