JP2024517820A - 動的造影磁気共鳴断層撮影を使用した肝臓における病変の特性決定 - Google Patents

動的造影磁気共鳴断層撮影を使用した肝臓における病変の特性決定 Download PDF

Info

Publication number
JP2024517820A
JP2024517820A JP2023567939A JP2023567939A JP2024517820A JP 2024517820 A JP2024517820 A JP 2024517820A JP 2023567939 A JP2023567939 A JP 2023567939A JP 2023567939 A JP2023567939 A JP 2023567939A JP 2024517820 A JP2024517820 A JP 2024517820A
Authority
JP
Japan
Prior art keywords
liver
phase
image
reference tissue
contrast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023567939A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024517820A5 (https=
Inventor
シュッツ,グンナー
クノーブロッホ,ゲジネ
Original Assignee
バイエル・アクチエンゲゼルシヤフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by バイエル・アクチエンゲゼルシヤフト filed Critical バイエル・アクチエンゲゼルシヤフト
Publication of JP2024517820A publication Critical patent/JP2024517820A/ja
Publication of JP2024517820A5 publication Critical patent/JP2024517820A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222Evaluating particular parts, e.g. particular organs
    • A61B5/4244Evaluating particular parts, e.g. particular organs liver
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10Organic compounds
    • A61K49/101Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5602Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by filtering or weighting based on different relaxation times within the sample, e.g. T1 weighting using an inversion pulse
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5608Data processing and visualization specially adapted for MR, e.g. for feature analysis and pattern recognition on the basis of measured MR data, segmentation of measured MR data, edge contour detection on the basis of measured MR data, for enhancing measured MR data in terms of signal-to-noise ratio by means of noise filtering or apodization, for enhancing measured MR data in terms of resolution by means for deblurring, windowing, zero filling, or generation of gray-scaled images, colour-coded images or images displaying vectors instead of pixels
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • G06T7/0014Biomedical image inspection using an image reference approach
    • G06T7/0016Biomedical image inspection using an image reference approach involving temporal comparison
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/30Determination of transform parameters for the alignment of images, i.e. image registration
    • G06T7/33Determination of transform parameters for the alignment of images, i.e. image registration using feature-based methods
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10072Tomographic images
    • G06T2207/10088Magnetic resonance imaging [MRI]
    • G06T2207/10096Dynamic contrast-enhanced magnetic resonance imaging [DCE-MRI]
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30056Liver; Hepatic
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30096Tumor; Lesion

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • High Energy & Nuclear Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Signal Processing (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Artificial Intelligence (AREA)
  • Theoretical Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Physiology (AREA)
  • Quality & Reliability (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2023567939A 2021-05-07 2022-04-28 動的造影磁気共鳴断層撮影を使用した肝臓における病変の特性決定 Pending JP2024517820A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21172677.3 2021-05-07
EP21172677 2021-05-07
PCT/EP2022/061289 WO2022233689A1 (de) 2021-05-07 2022-04-28 Charakterisierung von läsionen in der leber mittels dynamischer kontrastverstärkter magnetresonanztomographie

Publications (2)

Publication Number Publication Date
JP2024517820A true JP2024517820A (ja) 2024-04-23
JP2024517820A5 JP2024517820A5 (https=) 2025-04-10

Family

ID=75870425

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023567939A Pending JP2024517820A (ja) 2021-05-07 2022-04-28 動的造影磁気共鳴断層撮影を使用した肝臓における病変の特性決定

Country Status (6)

Country Link
US (1) US20240225448A1 (https=)
EP (1) EP4334733B1 (https=)
JP (1) JP2024517820A (https=)
CN (1) CN117242362A (https=)
CA (1) CA3219070A1 (https=)
WO (1) WO2022233689A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7803779B2 (ja) * 2022-04-27 2026-01-21 富士フイルム株式会社 磁気共鳴イメージング装置、及び、その制御方法
CN118902432A (zh) * 2024-07-19 2024-11-08 暨南大学附属第一医院(广州华侨医院) 磁共振肝脏半智能化一站式检查方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060064396A1 (en) * 2004-04-14 2006-03-23 Guo-Qing Wei Liver disease diagnosis system, method and graphical user interface
JP2010119850A (ja) * 2008-11-22 2010-06-03 General Electric Co <Ge> 統計モデルを用いた医療画像自動セグメンテーションシステム、装置並びにプロセッサ
US20120070055A1 (en) * 2010-09-22 2012-03-22 Siemens Aktiengesellschaft Method and System for Liver Lesion Detection
JP2018521017A (ja) * 2015-06-04 2018-08-02 バイエル・ファルマ・アクティエンゲゼルシャフト 磁気共鳴画像法における使用のための新規ガドリニウムキレート化合物
WO2021069343A1 (de) * 2019-10-11 2021-04-15 Bayer Aktiengesellschaft Beschleunigung von mrt-untersuchungen
US20220318991A1 (en) * 2021-04-01 2022-10-06 GE Precision Healthcare LLC Artificial intelligence assisted diagnosis and classification of liver cancer from image data

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6039931A (en) 1989-06-30 2000-03-21 Schering Aktiengesellschaft Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
CN101421745B (zh) 2004-04-15 2016-05-11 美国医软科技公司 空间-时间肿瘤检测,分割和诊断信息提取系统及方法
US9251585B2 (en) 2007-07-12 2016-02-02 Siemens Aktiengesellschaft Coregistration and analysis of multi-modal images obtained in different geometries
US8229188B2 (en) * 2007-10-12 2012-07-24 General Electric Company Systems, methods and apparatus automatic segmentation of liver in multiphase contrast-enhanced medical images
EP3629898A4 (en) 2017-05-30 2021-01-20 Arterys Inc. AUTOMATED LESION DETECTION, SEGMENTATION AND LENGTH IDENTIFICATION
CN110709943B (zh) 2017-06-16 2023-11-28 珀金埃尔默细胞科技德国公司 使用沿骨骼的人造界标进行三维图像的自动失真校正和/或共同配准的系统和方法
US11633146B2 (en) 2019-01-04 2023-04-25 Regents Of The University Of Minnesota Automated co-registration of prostate MRI data
EP4597424A3 (en) 2019-01-07 2025-10-29 Exini Diagnostics AB Systems and methods for platform agnostic whole body image segmentation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060064396A1 (en) * 2004-04-14 2006-03-23 Guo-Qing Wei Liver disease diagnosis system, method and graphical user interface
JP2010119850A (ja) * 2008-11-22 2010-06-03 General Electric Co <Ge> 統計モデルを用いた医療画像自動セグメンテーションシステム、装置並びにプロセッサ
US20120070055A1 (en) * 2010-09-22 2012-03-22 Siemens Aktiengesellschaft Method and System for Liver Lesion Detection
JP2018521017A (ja) * 2015-06-04 2018-08-02 バイエル・ファルマ・アクティエンゲゼルシャフト 磁気共鳴画像法における使用のための新規ガドリニウムキレート化合物
WO2021069343A1 (de) * 2019-10-11 2021-04-15 Bayer Aktiengesellschaft Beschleunigung von mrt-untersuchungen
US20220318991A1 (en) * 2021-04-01 2022-10-06 GE Precision Healthcare LLC Artificial intelligence assisted diagnosis and classification of liver cancer from image data

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHRISTOPH J. ZECH ET AL.: "Consensus report from the 8th International Forum for Liver Magnetic Resonance Imaging", EUROPEAN RADIOLOGY, vol. 30, JPN7026000138, 2020, pages 370 - 382, ISSN: 0005775428 *

Also Published As

Publication number Publication date
CN117242362A (zh) 2023-12-15
CA3219070A1 (en) 2022-11-10
EP4334733A1 (de) 2024-03-13
US20240225448A1 (en) 2024-07-11
EP4334733B1 (de) 2026-01-21
WO2022233689A1 (de) 2022-11-10

Similar Documents

Publication Publication Date Title
Haimerl et al. Assessment of clinical signs of liver cirrhosis using T1 mapping on Gd-EOB-DTPA-enhanced 3T MRI
Li et al. Tumor response assessments with diffusion and perfusion MRI
Jackson et al. Reproducibility of quantitative dynamic contrast-enhanced MRI in newly presenting glioma
Petrillo et al. Standardized Index of Shape (SIS): a quantitative DCE-MRI parameter to discriminate responders by non-responders after neoadjuvant therapy in LARC
Moon et al. Dynamic contrast-enhanced breast MR imaging
Shiraishi et al. Computer‐aided diagnosis for the classification of focal liver lesions by use of contrast‐enhanced ultrasonography
JP2022549604A (ja) 教師あり学習によって訓練された予測モデルによるmri画像の予測
JP2011512963A (ja) 組織における変化を撮像するためのシステムおよび方法
Re et al. Enhancing pancreatic adenocarcinoma delineation in diffusion derived intravoxel incoherent motion f‐maps through automatic vessel and duct segmentation
Riches et al. Multivariate modelling of prostate cancer combining magnetic resonance derived T2, diffusion, dynamic contrast-enhanced and spectroscopic parameters
JP2022552484A (ja) Mri検査の高速化
Braunagel et al. Dynamic contrast-enhanced magnetic resonance imaging measurements in renal cell carcinoma: effect of region of interest size and positioning on interobserver and intraobserver variability
Wang et al. Dynamic contrast-enhanced MR imaging in renal cell carcinoma: reproducibility of histogram analysis on pharmacokinetic parameters
US20240225448A1 (en) Characterising lesions in the liver using dynamic contrast-enhanced magnetic resonance tomography
van Laarhoven et al. Method for quantitation of dynamic MRI contrast agent uptake in colorectal liver metastases
Balci et al. Low-dose gadobenate dimeglumine versus standard-dose gadopentate dimeglumine for delayed contrast-enhanced cardiac magnetic resonance imaging
Battal et al. Diffusion-weighted imaging in the characterization of focal liver lesions: efficacy of visual assessment
Bultman et al. Quantitative hepatic perfusion modeling using DCE‐MRI with sequential breathholds
Krepkin et al. Dynamic contrast-enhanced MR renography for renal function evaluation in ureteropelvic junction obstruction: feasibility study
Makkat et al. Quantification of perfusion and permeability in breast tumors with a deconvolution‐based analysis of second‐bolus T1‐DCE data
US8848998B1 (en) Automated method for contrast media arrival detection for dynamic contrast enhanced MRI
Hales et al. A two-stage model for in vivo assessment of brain tumor perfusion and abnormal vascular structure using arterial spin labeling
Donati et al. 3 T MR perfusion of solid pancreatic lesions using dynamic contrast-enhanced DISCO sequence: Usefulness of qualitative and quantitative analyses in a pilot study
US8275181B2 (en) Method for tracking of contrast enhancement pattern for pharmacokinetic and parametric analysis in fast-enhancing tissues using high-resolution MRI
Gill et al. An investigation into the effects of temporal resolution on hepatic dynamic contrast-enhanced MRI in volunteers and in patients with hepatocellular carcinoma

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250402

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250402

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20260116

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20260120

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20260420