JP2024504364A5 - - Google Patents
Info
- Publication number
- JP2024504364A5 JP2024504364A5 JP2023544292A JP2023544292A JP2024504364A5 JP 2024504364 A5 JP2024504364 A5 JP 2024504364A5 JP 2023544292 A JP2023544292 A JP 2023544292A JP 2023544292 A JP2023544292 A JP 2023544292A JP 2024504364 A5 JP2024504364 A5 JP 2024504364A5
- Authority
- JP
- Japan
- Prior art keywords
- membered
- alkyl
- group
- alkyls
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163140314P | 2021-01-22 | 2021-01-22 | |
| US63/140,314 | 2021-01-22 | ||
| PCT/US2022/013383 WO2022159746A1 (en) | 2021-01-22 | 2022-01-21 | Gcn2 modulating compounds and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026088382A Division JP2026133645A (ja) | 2021-01-22 | 2026-05-26 | Ｇｃｎ２をモジュレートする化合物およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024504364A JP2024504364A (ja) | 2024-01-31 |
| JP2024504364A5 true JP2024504364A5 (cg-RX-API-DMAC10.html) | 2025-01-28 |
Family
ID=80446635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023544292A Pending JP2024504364A (ja) | 2021-01-22 | 2022-01-21 | Ｇｃｎ２をモジュレートする化合物およびその使用 |
Country Status (14)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202008749D0 (en) | 2020-06-09 | 2020-07-22 | Ip2Ipo Innovations Ltd | Novel compounds |
| KR20250017238A (ko) * | 2022-05-25 | 2025-02-04 | 히버셀, 인크. | 암을 치료하기 위한 gcn2 조정제 |
| WO2024077092A1 (en) * | 2022-10-04 | 2024-04-11 | Hibercell, Inc. | Gcn2 inhibitor for treating metastases |
| EP4652170A1 (en) * | 2023-01-20 | 2025-11-26 | Hibercell, Inc. | Crystalline forms of 6-(3-((5-chloro-2-methoxypyridine)-3- sulfonamido)-2,6-difluorophenyl)-n-methylimidazo[l,5- ajpyrazine-l-carboxamide and methods for using the same |
| IL328829A (en) * | 2023-12-08 | 2026-08-01 | Hibercell Inc | Methods for treating acute myeloid leukemia using combinations of GCN2 modulators, ventocalx and azaraglitidine |
| WO2025137710A1 (en) * | 2023-12-22 | 2025-06-26 | Hibercell, Inc. | Methods of treating cancer using combinations of gcn2 modulators and belzutifan |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005034869A2 (en) * | 2003-10-08 | 2005-04-21 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| ES2422263T3 (es) * | 2008-12-19 | 2013-09-10 | Nerviano Medical Sciences Srl | Pirazoles bicíclicos como inhibidores de la proteinquinasa |
| PL3498693T3 (pl) * | 2016-08-10 | 2025-03-24 | Takeda Pharmaceutical Company Limited | Związek heterocykliczny |
| CA3089762A1 (en) * | 2018-01-29 | 2019-08-01 | Merck Patent Gmbh | Gcn2 inhibitors and uses thereof |
| WO2020210828A1 (en) * | 2019-04-12 | 2020-10-15 | Hibercell, Inc. | (aza)indazolyl-aryl sulfonamide and related compounds and their use in treating medical conditions |
| EP4107146A1 (en) * | 2020-02-17 | 2022-12-28 | Alesta Therapeutics BV | Gcn2 modulator compounds |
-
2022
- 2022-01-21 KR KR1020237028260A patent/KR20240021143A/ko active Pending
- 2022-01-21 PE PE2023002158A patent/PE20240691A1/es unknown
- 2022-01-21 AU AU2022210760A patent/AU2022210760A1/en active Pending
- 2022-01-21 CA CA3209124A patent/CA3209124A1/en active Pending
- 2022-01-21 EP EP22704111.8A patent/EP4281182A1/en active Pending
- 2022-01-21 WO PCT/US2022/013383 patent/WO2022159746A1/en not_active Ceased
- 2022-01-21 BR BR112023014723A patent/BR112023014723A2/pt unknown
- 2022-01-21 US US18/262,493 patent/US20240083897A1/en active Pending
- 2022-01-21 MX MX2023008589A patent/MX2023008589A/es unknown
- 2022-01-21 JP JP2023544292A patent/JP2024504364A/ja active Pending
- 2022-01-21 CR CR20230408A patent/CR20230408A/es unknown
- 2022-01-21 CN CN202280022926.3A patent/CN117203206A/zh active Pending
-
2023
- 2023-07-20 IL IL304611A patent/IL304611A/en unknown
- 2023-08-22 CO CONC2023/0010940A patent/CO2023010940A2/es unknown