JP2023512297A5 - - Google Patents

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Publication number
JP2023512297A5
JP2023512297A5 JP2022547063A JP2022547063A JP2023512297A5 JP 2023512297 A5 JP2023512297 A5 JP 2023512297A5 JP 2022547063 A JP2022547063 A JP 2022547063A JP 2022547063 A JP2022547063 A JP 2022547063A JP 2023512297 A5 JP2023512297 A5 JP 2023512297A5
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JP
Japan
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Application number
JP2022547063A
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English (en)
Japanese (ja)
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JP7840516B2 (ja
JP2023512297A (ja
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Priority claimed from PCT/US2021/016104 external-priority patent/WO2021155380A1/en
Publication of JP2023512297A publication Critical patent/JP2023512297A/ja
Publication of JP2023512297A5 publication Critical patent/JP2023512297A5/ja
Application granted granted Critical
Publication of JP7840516B2 publication Critical patent/JP7840516B2/ja
Active legal-status Critical Current
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JP2022547063A 2020-01-31 2021-02-01 二重特異性t細胞エンゲージャー Active JP7840516B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062968999P 2020-01-31 2020-01-31
US62/968,999 2020-01-31
PCT/US2021/016104 WO2021155380A1 (en) 2020-01-31 2021-02-01 Bispecific t cell engagers

Publications (3)

Publication Number Publication Date
JP2023512297A JP2023512297A (ja) 2023-03-24
JP2023512297A5 true JP2023512297A5 (https=) 2024-08-15
JP7840516B2 JP7840516B2 (ja) 2026-04-06

Family

ID=77079996

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022547063A Active JP7840516B2 (ja) 2020-01-31 2021-02-01 二重特異性t細胞エンゲージャー

Country Status (7)

Country Link
US (1) US11976133B2 (https=)
EP (1) EP4097135A4 (https=)
JP (1) JP7840516B2 (https=)
KR (1) KR20220162690A (https=)
CN (1) CN115643806A (https=)
AU (1) AU2021213840A1 (https=)
WO (1) WO2021155380A1 (https=)

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US12060434B2 (en) * 2020-02-25 2024-08-13 Gensun Biopharma Inc. Trispecific T cell engagers
US12486331B2 (en) * 2020-01-31 2025-12-02 Gensun Biopharma Inc. Bispecific T cell engagers
CA3192204A1 (en) 2020-08-19 2022-02-24 Xencor, Inc. Anti-cd28 and/or anti-b7h3 compositions
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
AU2023217790A1 (en) * 2022-02-10 2024-08-22 Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. Bispecific antigen-binding molecule and use thereof
US12365743B2 (en) 2022-02-23 2025-07-22 Xencor, Inc. Anti-CD28 x anti-PSMA antibodies
KR20240153575A (ko) 2022-02-23 2024-10-23 암젠 인크 Dll3을 표적화하는 암 치료
US20250249094A1 (en) * 2022-04-08 2025-08-07 The Wistar Institute Of Anatomy And Biology Combinations of Bispecific T cell Engagers and Methods of Use Thereof
WO2023204290A1 (ja) * 2022-04-21 2023-10-26 愛知県 多重特異性ナノ粒子
JP2025516805A (ja) * 2022-05-20 2025-05-30 アイ-エムエービー バイオファーマ ユーエス リミテッド 固形腫瘍を治療する方法
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
TW202532431A (zh) * 2023-09-21 2025-08-16 大陸商樂普創一生物科技(上海)有限公司 多特異性抗體及其用途
AU2024360465A1 (en) 2023-10-12 2026-04-09 Revolution Medicines, Inc. Macrocyclic ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025206223A1 (ja) * 2024-03-28 2025-10-02 早智子 月田 抗ヒトクローディン18.2抗体及びその使用
WO2025222087A2 (en) * 2024-04-19 2025-10-23 The Brigham And Women's Hospital, Inc. Klrb1 binding agents and methods of use thereof
TW202547461A (zh) 2024-05-17 2025-12-16 美商銳新醫藥公司 Ras抑制劑
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
WO2025264220A1 (en) * 2024-06-20 2025-12-26 Gensun Biopharma Inc. Multi-specific molecules and methods of use and making thereof
WO2025265060A1 (en) 2024-06-21 2025-12-26 Revolution Medicines, Inc. Therapeutic compositions and methods for managing treatment-related effects
WO2026006747A1 (en) 2024-06-28 2026-01-02 Revolution Medicines, Inc. Ras inhibitors
WO2026015790A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015796A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015801A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Methods of treating a ras related disease or disorder
WO2026015825A1 (en) 2024-07-12 2026-01-15 Revolution Medicines, Inc. Use of ras inhibitor for treating pancreatic cancer
WO2026050446A1 (en) 2024-08-29 2026-03-05 Revolution Medicines, Inc. Ras inhibitors
WO2026072904A2 (en) 2024-09-26 2026-04-02 Revolution Medicines, Inc. Compositions and methods for treating lung cancer
CN120168667B (zh) * 2025-03-18 2026-04-14 中国科学院近代物理研究所 一种多肽在制备dll3过度表达的肿瘤的特异性靶向分子探针中的应用

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EP2370467B1 (en) * 2008-10-01 2016-09-07 Amgen Research (Munich) GmbH Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
CA2894879A1 (en) * 2012-12-19 2014-06-26 Amplimmune, Inc. B7-h4 specific antibodies, and compositions and methods of use thereof
GB201302447D0 (en) * 2013-02-12 2013-03-27 Oxford Biotherapeutics Ltd Therapeutic and diagnostic target
CN105722859B (zh) * 2013-07-25 2021-05-07 西托姆克斯治疗公司 多特异性抗体、多特异性可活化抗体及其使用方法
MA41613A (fr) * 2015-02-23 2018-01-02 Abbvie Stemcentrx Llc Récepteurs antigéniques chimériques anti-dll3 et procédés d'utilisation desdits récepteurs
TWI793062B (zh) * 2015-07-31 2023-02-21 德商安美基研究(慕尼黑)公司 Dll3及cd3抗體構築體
US20200157224A1 (en) * 2017-06-25 2020-05-21 Systimmune, Inc. Multi-specific antibodies and methods of making and using thereof
MA51747A (fr) * 2018-02-08 2020-12-16 Amgen Inc Formulation d'anticorps pharmaceutique à ph faible
TWI848953B (zh) * 2018-06-09 2024-07-21 德商百靈佳殷格翰國際股份有限公司 針對癌症治療之多特異性結合蛋白

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