JP2023510853A5 - - Google Patents

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Publication number
JP2023510853A5
JP2023510853A5 JP2022542739A JP2022542739A JP2023510853A5 JP 2023510853 A5 JP2023510853 A5 JP 2023510853A5 JP 2022542739 A JP2022542739 A JP 2022542739A JP 2022542739 A JP2022542739 A JP 2022542739A JP 2023510853 A5 JP2023510853 A5 JP 2023510853A5
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JP
Japan
Prior art keywords
cancer
expression vector
individual
use according
wild
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022542739A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023510853A (ja
JP7815124B2 (ja
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Priority claimed from PCT/US2021/013130 external-priority patent/WO2021146213A1/en
Publication of JP2023510853A publication Critical patent/JP2023510853A/ja
Publication of JP2023510853A5 publication Critical patent/JP2023510853A5/ja
Application granted granted Critical
Publication of JP7815124B2 publication Critical patent/JP7815124B2/ja
Active legal-status Critical Current
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Links

JP2022542739A 2020-01-13 2021-01-12 Gm-csfをコードするポリヌクレオチドと追加薬剤を用いてがんを治療する方法 Active JP7815124B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202062960583P 2020-01-13 2020-01-13
US62/960,583 2020-01-13
US202063034868P 2020-06-04 2020-06-04
US63/034,868 2020-06-04
US202063061634P 2020-08-05 2020-08-05
US63/061,634 2020-08-05
PCT/US2021/013130 WO2021146213A1 (en) 2020-01-13 2021-01-12 Methods for treating cancers using gm-csf encoding polynucleotide and additional agents

Publications (3)

Publication Number Publication Date
JP2023510853A JP2023510853A (ja) 2023-03-15
JP2023510853A5 true JP2023510853A5 (https=) 2024-01-18
JP7815124B2 JP7815124B2 (ja) 2026-02-17

Family

ID=76857765

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022542739A Active JP7815124B2 (ja) 2020-01-13 2021-01-12 Gm-csfをコードするポリヌクレオチドと追加薬剤を用いてがんを治療する方法

Country Status (5)

Country Link
US (1) US11400170B2 (https=)
EP (1) EP4090380A1 (https=)
JP (1) JP7815124B2 (https=)
CN (1) CN115335085A (https=)
CA (1) CA3158900A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4440704A2 (en) * 2021-11-30 2024-10-09 Gradalis, Inc. Methods for treatment response to cancers
WO2025117756A1 (en) * 2023-11-28 2025-06-05 Gradalis, Inc. Neoantigen immunotherapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916530B2 (en) 2005-11-18 2014-12-23 Gradalis, Inc. Individualized cancer therapy
US8906874B2 (en) 2006-11-09 2014-12-09 Gradalis, Inc. Bi-functional shRNA targeting Stathmin 1 and uses thereof
US8758998B2 (en) 2006-11-09 2014-06-24 Gradalis, Inc. Construction of bifunctional short hairpin RNA
US8252526B2 (en) 2006-11-09 2012-08-28 Gradalis, Inc. ShRNA molecules and methods of use thereof
EP2217244A4 (en) * 2007-11-12 2011-08-31 Bipar Sciences Inc TREATMENT OF NUTRITIONAL CANCER AND EGG CANCER WITH A PARP INHIBITOR ALONE OR IN COMBINATION WITH ANTITUMOROUS MEDICINES
US8969068B2 (en) 2008-04-30 2015-03-03 Gradalis, Inc. Processes for the preparation of highly pure plasmid compositions by enzymatic digestion of colanic acid
CA2772057C (en) 2009-09-03 2016-02-02 Strike Bio, Inc. Targeted delivery using tissue-specific peptidomimetic ligands
KR101543350B1 (ko) 2009-10-30 2015-08-11 베이롤 칼리지 오브 메드신 Pdx-1을 발현하는 신경내분비 종양에서 pdx-1 종양유전자를 표적화한 신규한 치료용 rna 간섭 기법
US9157084B2 (en) * 2009-12-23 2015-10-13 Gradalis, Inc. Furin-knockdown bi-functional RNA
SG181880A1 (en) * 2009-12-23 2012-07-30 Gradalis Inc Furin-knockdown and gm-csf-augmented (fang) cancer vaccine
WO2015086473A1 (en) 2013-12-09 2015-06-18 Institut Curie Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
SG11201811564QA (en) * 2016-06-29 2019-01-30 Tesaro Inc Methods of treating ovarian cancer

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