JP2023501388A - 操作された制御性ｔ細胞の生成 - Google Patents

操作された制御性ｔ細胞の生成 Download PDF

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JP2023501388A
JP2023501388A JP2022526138A JP2022526138A JP2023501388A JP 2023501388 A JP2023501388 A JP 2023501388A JP 2022526138 A JP2022526138 A JP 2022526138A JP 2022526138 A JP2022526138 A JP 2022526138A JP 2023501388 A JP2023501388 A JP 2023501388A
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cells
cell
treg
gene
sequence
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JP2023501388A5 (https=
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コンウェイ，アンソニー
フォン，ヘレン
クォン，ジョージ
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Sangamo Therapeutics Inc
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Sangamo Therapeutics Inc
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JP2022526138A 2019-11-08 2020-11-09 操作された制御性ｔ細胞の生成 Pending JP2023501388A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962933252P 2019-11-08 2019-11-08
US62/933,252 2019-11-08
PCT/US2020/059730 WO2021092581A1 (en) 2019-11-08 2020-11-09 Generation of engineered regulatory t cells

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JP2023501388A true JP2023501388A (ja) 2023-01-18
JP2023501388A5 JP2023501388A5 (https=) 2023-11-16

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US (1) US20220380727A1 (https=)
EP (1) EP4055039A1 (https=)
JP (1) JP2023501388A (https=)
KR (1) KR20220095223A (https=)
CN (1) CN114710958A (https=)
AU (1) AU2020378228A1 (https=)
CA (1) CA3160113A1 (https=)
IL (1) IL292676A (https=)
WO (1) WO2021092581A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116323921A (zh) * 2020-10-28 2023-06-23 桑格摩生物治疗股份有限公司 从人多能干细胞生成cd4+效应t细胞和调节性t细胞
US11459372B2 (en) 2020-11-30 2022-10-04 Crispr Therapeutics Ag Gene-edited natural killer cells
WO2022144632A1 (en) 2020-12-30 2022-07-07 Crispr Therapeutics Ag Compositions and methods for differentiating stem cells into nk cells
WO2022165419A1 (en) 2021-02-01 2022-08-04 Kyverna Therapeutics, Inc. Methods for increasing t-cell function
AU2022349176A1 (en) 2021-09-27 2024-04-11 Kyoto University Method for producing t cell
CN119256076A (zh) 2022-03-23 2025-01-03 国立大学法人京都大学 用于产生调节性t细胞的方法
EP4600352A1 (en) 2022-09-26 2025-08-13 Kyoto University T cell production method
US20250270583A1 (en) * 2022-10-26 2025-08-28 Biodrive, Inc. Methods for Suppression of Gene Silencing in Plants
WO2024145653A2 (en) * 2022-12-30 2024-07-04 Bluerock Therapeutics Lp Engineered cells for the production of cd4+ t cells and cd4+ tregs
GB202312699D0 (en) * 2023-08-18 2023-10-04 Cambridge Entpr Ltd Controllable expression in mammalian cells
WO2025223995A1 (en) * 2024-04-26 2025-10-30 Tcbalance Biopharmaceuticals Gmbh Gene-modified t regulatory cell

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WO2019210078A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of human foxp3 in gene edited t cells

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WO2014165707A2 (en) * 2013-04-03 2014-10-09 Memorial Sloan-Kettering Cancer Center Effective generation of tumor-targeted t-cells derived from pluripotent stem cells
WO2017062035A1 (en) * 2015-10-09 2017-04-13 Abt Holding Company Methods for enhancing proliferation of t regulatory cells
CA3042179A1 (en) * 2016-10-31 2018-05-03 Seattle Children's Hospital (dba Seattle Children's Research Institute) Method for treating autoimmune disease using cd4 t-cells with engineered stabilization of expression of endogenous foxp3 gene
FR3079239A1 (fr) * 2018-03-23 2019-09-27 Centre National De La Recherche Scientifique Nouvelle methode d’obtention de cellules t a partir de cellules souches pluripotentes, et leurs utilisations
AU2019261438B2 (en) 2018-04-27 2024-08-22 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of FOXP3 in edited CD34+ cells

Patent Citations (1)

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WO2019210078A1 (en) * 2018-04-27 2019-10-31 Seattle Children's Hospital (dba Seattle Children's Research Institute) Expression of human foxp3 in gene edited t cells

Non-Patent Citations (1)

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Title
JAYATI MOOKERJEE-BASU ET AL.: ""ThPOK, a Key Regulator of T Cell Development and Function"", SIGNALING MECHANISMS REGULATING T CELL DIVERSITY AND FUNCTION, JPN6024040878, 27 March 2017 (2017-03-27), pages 67 - 83, ISSN: 0005591898 *

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CA3160113A1 (en) 2021-05-14
IL292676A (en) 2022-07-01
EP4055039A1 (en) 2022-09-14
US20220380727A1 (en) 2022-12-01
AU2020378228A1 (en) 2022-05-26
WO2021092581A9 (en) 2022-06-23
WO2021092581A1 (en) 2021-05-14
CN114710958A (zh) 2022-07-05
KR20220095223A (ko) 2022-07-06

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