JP2023158448A - needle system - Google Patents

Abstract

To provide a needle system allowing an operator to acquire the depth of a needle punctured into an internal organ.SOLUTION: A needle system 1 includes a resin tube 10 having a lumen 11 extending in a longitudinal direction x, a needle 20 made of a conductive material, disposed in the lumen 11 of the resin tube 10 movably with respect to the resin tube 10, and being punctured into an internal organ, a counter electrode 30 disposed on a body surface, and a measuring instrument 40 for measuring electric resistance between the needle 20 and the counter electrode 30 when a current is passed between the needle 20 and the counter electrode 30.SELECTED DRAWING: Figure 1

Description

The present invention relates to a needle system having a needle that punctures an organ within the body.

BACKGROUND ART Treatments have been carried out to regenerate myocardial cells, which are losing their function due to myocardial infarction, by directly administering a drug solution such as myocardial regenerating cell preparations. In this way, when administering a medicinal solution directly to an internal organ, it is necessary to insert a catheter with a needle into the body cavity and puncture the organ with the needle. At this time, if the puncture depth of the needle is too shallow and the hole for administering the drug solution is not located within the organ, the drug solution cannot be administered to the organ. Therefore, it is desired to develop a needle that can recognize whether or not the needle has been punctured until the hole for administering the drug solution is located inside the organ, and that can reliably administer the drug solution to the organ. was.

Patent Document 1 describes a hollow needle for puncturing the myocardium of a patient and injecting a drug solution, which includes a sharp metal tip member and an electrically insulating needle connected to the proximal side of the tip member. A connecting tube, a metal tube connected to the proximal end side of the connecting tube, and an insulating layer covering the outer circumferential surface of the proximal end portion of the metal tube, and the connecting tube and/or the tip member include a needle lumen. At least one hole (chemical solution outflow path) is formed that communicates with the connecting tube or the outer surface of the tip member, and the electrode for potential measurement is formed by the tip portion of the metal tube that is not covered with an insulating layer. It describes the chemical liquid injection needle configured. This drug injection needle easily determines whether the drug injection opening is located inside the heart wall by checking whether the potential measured by the electrode is above a predetermined value. By confirming that the potential is equal to or higher than a predetermined value and performing the injection operation of the drug solution, the drug solution can be reliably injected into the myocardium from the opening of the hole.

Patent Document 2 describes a metal sharp tip member, an electrically insulating connecting tube connected to the proximal side of the tip member, a metal tube connected to the proximal side of the connecting tube, and a metal tube. an insulating layer covering the outer peripheral surface of the proximal end portion, and the connecting tube and/or the tip member has at least one hole that communicates with the lumen of the needle and opens on the outer surface of the connecting tube or the tip member. The distal end portion of the metal tube formed and not covered with an insulating layer constitutes an electrode for potential measurement, and the first potential measured by the distal end electrode is equal to or higher than the first threshold value, and when the liquid injection needle is A liquid drug injection needle system is described that includes a notification means for notifying an operator that injection of a drug liquid into the myocardium is possible when a second potential measured by an electrode is equal to or higher than a second threshold value. . This drug solution injection needle system is operated when the first potential measured by the tip electrode of the electrode catheter becomes equal to or higher than the first threshold value, and the second potential measured by the electrode of the drug solution injection needle becomes equal to or higher than the second threshold value. By waiting for the notification from the notification means and performing the injection operation of the medicinal solution, the medicinal solution can be reliably injected into the myocardium of the patient.

Patent Document 3 describes a hollow needle for puncturing a patient's myocardium and injecting a medical solution, and a first electrode for potential measurement made of a sharp metal member with a closed tip; An electrically insulating connecting pipe connected to the proximal end of the connecting pipe, a metal pipe connected to the proximal end of the connecting pipe, and an insulating coating layer covering the outer peripheral surface of the proximal end of the metal pipe. At least one side hole (outflow path for the drug solution) that communicates with the inner lumen of the needle (the inner lumen of the connecting tube) and opens on the outer circumferential surface of the connecting tube is formed in the wall of the tube, and an insulating coating is formed on the wall of the tube. This document describes a chemical liquid injection needle in which a second electrode for potential measurement is constituted by the distal end portion of a metal tube that is not covered with a layer. In this drug injection needle, when the potential measured by the first electrode and the potential measured by the second electrode are both equal to or higher than a predetermined value, the opening of the side hole formed in the wall of the connecting tube reaches the myocardium. By confirming that both potentials are at a predetermined value or higher and injecting the drug solution, the drug solution can be reliably injected into the myocardium from the opening of the side hole. It is something that can be done.

International Publication No. 2021/192283 International Publication No. 2021/192284 International Publication No. 2021/192285

However, the drug solution injection needles described in Patent Documents 1 to 3 do not have the effect of being able to reliably inject the drug solution into the myocardium by determining whether or not the hole has entered the myocardium. However, it was not possible to determine the needle puncture depth itself, which is how long the needle was inserted into the myocardium. Therefore, if the needle is inserted too far into the myocardium, the needle may penetrate the tissue and cause damage.

The present invention has been made in view of the above circumstances, and its purpose is to provide a needle system that can determine the depth of a needle punctured into an internal organ.

An embodiment of the needle system of the present invention that can solve the above problems is as follows.
[1] It is composed of a resin tube having a longitudinally extending lumen and an electrically conductive material, and is placed in the lumen of the resin tube so as to be movable relative to the resin tube, so that it does not affect organs in the body. A needle system includes a needle to be punctured, a counter electrode placed on the body surface, and a measuring device that measures electrical resistance between the needle and the counter electrode when a current is passed between the needle and the counter electrode.
The needle is placed in the lumen of the resin tube and is transported to the organ to be treated. After transportation, the distal end of the resin tube is brought into contact with the organ, and the position of the needle relative to the resin tube is moved distally while passing an electric current between the needle and the counter electrode. It protrudes from the distal end and punctures the organ. By passing a current between the needle and the counter electrode with the distal end of the resin tube in contact with the organ, the current flowing between the needle and the counter electrode will flow inside the organ. Therefore, the moment the needle punctures the organ, the electrical resistance between the needle and the counter electrode decreases. Furthermore, the deeper the needle punctured into the organ, the larger the contact area between the needle and the organ, which serves as an electrical flow path, and thus the electrical resistance between the needle and the counter electrode decreases. Therefore, by measuring the electrical resistance value between the needle and the counter electrode when a current is passed between the needle and the counter electrode, it is possible to understand the depth of the needle puncturing the organ from the change in value. .
[2] The needle system according to [1], wherein the needle has a lumen extending in the longitudinal direction.
[3] The needle system according to [2], wherein the distal end of the needle has an opening that communicates with the lumen of the needle.
[4] The needle has a side wall forming a lumen of the needle, and a hole communicating with the lumen of the needle is formed at the distal portion of the needle and in the side wall of the needle.[2] Or the needle system according to [3].
[5] The needle system according to [4], wherein a plurality of holes are formed on the side wall of the needle, and the plurality of holes are lined up in the longitudinal direction.
[6] The needle system according to any one of [1] to [5], wherein the needle is entirely made of metal.
[7] The needle system according to any one of [1] to [6], wherein the first insulating base material is disposed on the outer surface of the needle, including the distal end of the needle.
[8] The needle system according to [7], wherein the second insulating base material is disposed on the outer surface of the needle on the proximal side of the proximal end of the first insulating base material.

The needle system of the present invention measures the electrical resistance value between the needle and the counter electrode when a current is passed between the needle and the counter electrode, and determines the depth of the needle punctured into internal organs based on the change in value. It is something that can be grasped.

1 is a cross-sectional view (partially a side view) showing an example of a needle system according to an embodiment of the present invention. 2 is an enlarged cross-sectional view of the resin tube and the distal portion of the needle in the needle system shown in FIG. 1. FIG. 3 shows an end view of a section cut along line III-III shown in FIG. 2. FIG. 2 is an enlarged cross-sectional view of the resin tube and the distal portion of the needle in the needle system shown in FIG. 1. FIG. 5 is a side view (partially sectional view) showing a modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. Figure 6 depicts a cross-sectional view of the distal portion of the resin tube and needle shown in Figure 5; 6 shows an end view of a section cut along the line VII-VII shown in FIG. 5. FIG. 5 is a side view (partially sectional view) showing another modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. Figure 9 depicts a cross-sectional view of the distal portion of the resin tube and needle shown in Figure 8; 9 shows an end view of a section cut along the line XX shown in FIG. 8. FIG. 9 shows an end view of a section cut along the line XI-XI shown in FIG. 8. FIG. 5 is a side view (partially sectional view) showing another modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. Figure 13 depicts a cross-sectional view of the distal portion of the resin tube and needle shown in Figure 12; FIG. 13 shows an end view of a section cut along the line XIV-XIV shown in FIG. 12.

Hereinafter, the present invention will be specifically explained with reference to the drawings, but the present invention is not limited to the illustrated examples, and can be carried out with appropriate changes within the scope of the spirit described above and below. It is also possible to do so, and all of them are included within the technical scope of the present invention. In each figure, hatching, symbols, etc. may be omitted for convenience; in such cases, reference should be made to the specification and other figures. Further, the dimensions of various parts in the drawings are given priority to help understanding the features of the present invention, and therefore may differ from actual dimensions.

One embodiment of the needle system of the present invention comprises a resin tube having a longitudinally extending lumen and an electrically conductive material disposed in the lumen of the resin tube so as to be movable relative to the resin tube. A measurement that measures the electrical resistance between a needle inserted into an internal organ, a counter electrode placed on the body surface, and the needle and counter electrode when a current is passed between the needle and the counter electrode. The gist is that it has a vessel and.

The overall configuration of a needle system according to an embodiment of the present invention will be described with reference to FIGS. 1 to 14. In FIG. 1, a needle system 1 is shown having a resin tube 10, a needle 20, a counter electrode 30 and a measuring device 40. In this drawing, the longitudinal direction of the resin tube 10 is indicated by x, and the radial direction is indicated by y. The radial direction y is a direction perpendicular to the longitudinal direction x, but only one direction perpendicular to the longitudinal direction x is shown here. Note that the longitudinal direction x is the direction in which the resin tube 10 extends.

In this specification, the proximal side refers to the user's proximal side with respect to the extending direction of the resin tube 10, and the distal side refers to the side opposite to the proximal side, that is, the side to be treated. Moreover, the distal part of each member refers to the distal half of each member, and the proximal part of each member refers to the proximal half of each member.

FIG. 1 is a cross-sectional view (partially a side view) showing an example of a needle system according to an embodiment of the present invention. FIG. 2 shows an enlarged cross-sectional view of the distal portions of the resin tube 10 and needle 20 in the needle system 1 shown in FIG. FIG. 3 shows an end view of a section cut along the line III--III shown in FIG. FIG. 4 is an enlarged cross-sectional view of the distal portions of the resin tube 10 and needle 20 in the needle system 1 shown in FIG. FIG.

As shown in FIGS. 1 and 2, the needle system 1 includes a resin tube 10. As shown in FIGS. The resin tube 10 has a lumen 11 extending in the longitudinal direction x. As shown in FIG. 1, the resin tube 10 may have a distal end 10a and a proximal end 10b.

As shown in FIGS. 1 and 2, the needle system 1 has a needle 20. As shown in FIGS. The needle 20 is arranged in the lumen 11 of the resin tube 10 so as to be movable with respect to the resin tube 10, and is used to puncture an internal organ of the body. Internal organs refer to organs within the body, particularly in the abdomen and chest, and are also called internal organs. Further, since the needle 20 is made of a conductive material, it serves as an electrode. The entire needle 20 may be made of a conductive material, or only a portion thereof may be made of a conductive material.

As shown in FIG. 1, the needle system 1 has a counter electrode 30. The counter electrode 30 is an electrode placed on the body surface of the subject. The body surface refers to the part covered by the skin and directly facing the outside world. That is, areas covered by mucous membranes, such as the inside of the mouth and the lumen of the intestinal tract, are not included in the body surface.

As shown in FIG. 1, the needle system 1 has a measuring device 40. The measuring device 40 measures the electrical resistance between the needle 20 and the counter electrode 30 when a current is passed between the needle 20 and the counter electrode 30.

In the above needle system, as shown in FIGS. 1 and 2, the needle 20 is placed in the lumen 11 of the resin tube 10 and is transported to the organ to be treated. After transportation, the distal end of the resin tube 10 is brought into contact with the organ, and the position of the needle 20 relative to the resin tube 10 is moved distally while passing an electric current between the needle 20 and the counter electrode 30. A needle 20 is made to protrude from the distal end of the resin tube 10 and puncture the organ. FIG. 4 shows the needle 20 protruding from the distal end of the resin tube 10. By passing a current between the needle 20 and the counter electrode 30 with the distal end of the resin tube 10 in contact with the organ, the current flowing between the needle 20 and the counter electrode 30 flows inside the organ. That will happen. Therefore, the electrical resistance between the needle 20 and the counter electrode 30 decreases at the moment the needle 20 punctures the organ. Furthermore, the deeper the needle 20 punctures the organ, the larger the contact area between the needle 20 and the organ, which serves as an electrical flow path, and therefore the electrical resistance between the needle 20 and the counter electrode 30 decreases. Therefore, by measuring the electrical resistance value between the needle 20 and the counter electrode 30 when a current is passed between the needle 20 and the counter electrode 30, the depth of the needle 20 puncturing the organ can be determined from the change in value. can be grasped.

The needle system 1 can be used when directly administering a liquid such as a cell preparation or a drug solution to an organ in the body, such as the heart, kidney, liver, or the like. Specifically, it can be used to directly administer an iPS cell suspension to the liver or kidney, or to directly administer a myocardial regenerative cell preparation to the heart, more specifically, to the myocardium.

The resin tube 10 can be manufactured, for example, by extrusion molding. The resin tube 10 can be composed of a single layer or multiple layers. A portion of the resin tube 10 in the longitudinal direction x or the circumferential direction may be composed of a single layer, and the other portion may be composed of multiple layers.

The resin tube 10 is made of, for example, polyolefin resin (for example, polyethylene or polypropylene), polyamide resin (for example, nylon), polyester resin (for example, PET), aromatic polyetherketone resin (for example, PEEK), polyether polyamide resin, It can be composed of synthetic resins such as polyurethane resins, polyimide resins, and fluororesins (eg, PTFE, PFA, ETFE). These may be used alone or in combination of two or more.

As shown in FIG. 1, a first handle 51 may be connected to the proximal portion of the resin tube 10.

As shown in FIG. 1, the resin tube 10 may have a distal opening 12 and a proximal opening 13 communicating with the lumen 11.

After the needle 20 is placed in the lumen 11 of the resin tube 10 and is transported to the organ to be treated, the distal end of the resin tube 10 is brought into contact with the organ. It is preferable to contact the organ so that the opening 12 on the distal side is covered by the organ.

The needle 20 can puncture an organ within the body, such as the heart, kidney, liver, etc.

As shown in FIG. 1, a second handle 52 for manipulating the position of the needle 20 in the lumen 11 of the resin tube 10 may be connected to the proximal portion of the needle 20.

As shown in FIG. 1, the proximal end of the needle 20 is preferably located closer to the proximal end 10b of the resin tube 10. Thereby, the position of the needle 20 in the inner cavity 11 of the resin tube 10 can be easily manipulated.

As shown in FIG. 1, the length of the needle 20 is preferably longer than the length of the resin tube 10 in the longitudinal direction x of the resin tube 10. This makes it easier to transmit to the needle 20 torque in the rotational direction, that is, motion in the three-dimensional direction, in addition to the forward and backward pushing and pulling directions, so the position of the needle 20 in the inner cavity 11 of the resin tube 10 can be controlled. The needle 20 can be easily protruded from the distal end of the resin tube 10. This makes it easier to puncture the needle 20 into internal organs.

Needle 20 can be constructed from metal. The needle 20 may be entirely made of metal. Only a portion of the needle 20 may be made of metal, and the other portion may be made of a material other than metal, such as conductive resin.

Examples of the metal constituting the needle 20 include stainless steel such as SUS304 and SUS316, platinum, nickel, cobalt, chromium, titanium, tungsten, gold, Ni-Ti alloy, Co-Cr alloy, or a combination thereof. .

The needle 20 may have a portion made of a material having a higher electrical resistance value than the tissue to be punctured by the needle 20. Only a portion of the needle 20 may be made of a material having a higher electrical resistance value than the tissue to be punctured by the needle 20. As a result, the amount of electricity flowing through the portion made of a material having a higher electrical resistance value than the tissue to be punctured is reduced. Therefore, when the needle 20 punctures an organ, a decrease in electrical resistance tends to occur. This makes it easier to understand changes in the electrical resistance value, and makes it easier to understand the depth of the needle 20 puncturing the organ. Note that the entire needle 20 may be made of a material having a higher electrical resistance value than the tissue to be punctured by the needle 20. This makes it easier to increase the change in electrical resistance before and after puncturing the needle 20, making it easier to understand that the needle 20 has punctured an organ.

As shown in FIGS. 2 and 3, the needle 20 may have a lumen 21 extending in the longitudinal direction x of the resin tube 10. Thereby, a liquid such as a cell preparation or a drug solution can be injected into the lumen 21 of the needle 20.

As shown in FIG. 1, the needle system 1 may further include a liquid supply 54 connected to the second handle 52. In this case, it is preferable that the liquid supply device 54 be configured to be able to supply a liquid such as a cell preparation or a drug solution to the lumen 21 of the needle 20 . For example, the second handle 52 has a lumen, and the lumen of the second handle 52 and the lumen 21 of the needle 20 communicate with each other, so that liquids such as cell preparations and drug solutions supplied from the liquid supply device 54 can be delivered to the lumen. 2 can be fed into the lumen 21 of the needle 20 via the lumen of the handle 54. Although not shown, a liquid such as a cell preparation or a drug solution may be supplied to the lumen 21 of the needle 20 by directly connecting the proximal end of the needle 20 to the liquid supply device 54 .

As the liquid supply device 54, a known means for supplying liquid, such as a syringe or a pump, can be used.

The distal end of the needle 20 may have an opening 22 that communicates with the lumen 21 of the needle 20. The opening 22 provided at the distal end of the needle 20 refers to the opening portion that is visible when the resin tube 10 is observed from the longitudinal direction x. Preferably, opening 22 is formed in the distal end surface of needle 20. As shown in FIG. 2, the needle 20 has a distal end surface that is inclined with respect to the longitudinal direction x and the radial direction y of the resin tube 10, and may have an opening 22 in the inclined portion. Thereby, liquids such as cell preparations and drug solutions injected into the lumen 21 of the needle 20 can be discharged from the opening 22 provided at the distal end of the needle 20.

FIG. 5 is a side view (partially sectional view) showing a modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. 6 represents a cross-sectional view of the distal portion of the resin tube 10 and needle 20 shown in FIG. FIG. 7 shows an end view of a section cut along line VII-VII shown in FIG. FIG. 8 is a side view (partially sectional view) showing another modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. 9 represents a cross-sectional view of the distal portion of the resin tube 10 and needle 20 shown in FIG. 8. FIG. 10 shows an end view of a section cut along the line XX shown in FIG. FIG. 11 shows an end view of a section cut along the line XI-XI shown in FIG. FIG. 12 is a side view (partially sectional view) showing another modification of the resin tube and the distal portion of the needle shown in FIG. 4. FIG. 13 depicts a cross-sectional view of the distal portion of the resin tube and needle shown in FIG. 12. FIG. 14 shows an end view of a section cut along the line XIV-XIV shown in FIG.

As shown in FIGS. 5-14, the needle 20 has a sidewall 23 forming a lumen 21 of the needle 20, and a needle 20 disposed at a distal portion of the needle 20 and in the sidewall 23 of the needle 20. A hole 24 communicating with the inner cavity 21 may be formed. The hole 24 formed in the side wall 23 of the needle 20 refers to the hole that is visible when the resin tube 10 is observed from the radial direction y. With the above configuration, the flow path of electricity becomes narrow in the portion where the hole 24 is formed, so that the amount of electricity flowing is reduced. Therefore, when the needle 20 punctures an organ, a decrease in electrical resistance tends to occur. This makes it easier to understand changes in the electrical resistance value, and makes it easier to understand the depth of the needle 20 puncturing the organ. Further, liquid such as a cell preparation or a drug solution injected into the lumen 21 of the needle 20 can be discharged from the hole 24.

The number of holes 24 formed in the needle 20 is not particularly limited, but for example, only one hole 24 may be formed as shown in FIGS. 5 to 7, or as shown in FIGS. A plurality of them may be formed as shown in 14.

As shown in FIGS. 8 to 14, a plurality of holes 24 are formed in the side wall 23 of the needle 20, and the plurality of holes 24 may be lined up in the longitudinal direction x of the resin tube 10. With this configuration, the flow path of electricity becomes narrow in the portion where the hole 24 is formed, so that the amount of electricity flowing is reduced. Therefore, when the needle 20 punctures an organ, a decrease in electrical resistance tends to occur. This makes it easier to understand changes in the electrical resistance value, and makes it easier to understand the depth of the needle 20 puncturing the organ. Moreover, liquids such as cell preparations and drug solutions injected into the lumen 21 of the needle 20 can be discharged from the plurality of holes 24, and liquids such as cell preparations and drug solutions can be injected efficiently.

As shown in FIG. 4, the needle 20 may have only an opening 22 formed at the distal end and no hole 24 formed in the side wall 23. Although not shown, the needle 20 may have only a hole 24 formed in the side wall 23 and no opening 22 formed at the distal end. As shown in FIGS. 5-14, the needle 20 may have both an opening 22 formed at the distal end and a hole 24 formed in the side wall 23. As shown in FIGS.

As shown in FIGS. 5-10, a first insulating substrate 71 may be disposed on the outer surface of the needle 20, including the distal end of the needle 20. With this configuration, in the portion where the first insulating base material 71 is arranged, the contact area between the needle 20 and the organ does not increase, so the number of paths through which electricity flows does not increase. Therefore, while only the portion where the first insulating base material 71 is placed is punctured, the amount of electricity flowing remains constant. This makes it easier to recognize the decrease in electrical resistance when the needle 20 is punctured to a portion where the first insulating base material 71 is not placed. This makes it easier to understand changes in the electrical resistance value, and makes it easier to understand the depth of the needle 20 puncturing the organ.

As shown in FIGS. 8 to 11, a second insulating base material 72 may be disposed on the outer surface of the needle 20 on the proximal side of the proximal end of the first insulating base material 71. With this configuration, the contact area between the needle 20 and the organ does not increase in the portion where the second insulating base material 72 is arranged, so that the number of paths through which electricity flows between the needle and the organ does not increase. For this reason, the amount of electricity flowing remains constant while the part where the second insulating base material 72 is placed is the part where the second insulating base material 72 is newly entered into the organ. This makes it easier to recognize the decrease in electrical resistance when the needle 20 is punctured to a portion where the second insulating base material 72 is not placed. This makes it easier to understand changes in the electrical resistance value, and makes it easier to understand the depth of the needle 20 puncturing the organ.

The first insulating base material 71 and the second insulating base material 72 are members that are difficult to conduct electricity.

It is preferable that the first insulating base material 71 and the second insulating base material 72 are made of resin. Examples of the resin constituting the first insulating base material 71 and the second insulating base material 72 include polyimide resin, polyamide resin, polyolefin resin, polyester resin, polycarbonate resin, and epoxy resin. The first insulating base material 71 and the second insulating base material 72 may be made of the same resin or may be made of different resins.

As shown in FIGS. 8 and 9, a plurality of second insulating base materials 72 may be arranged on the outer surface of the needle 20. Although not shown, only one second insulating base material 72 may be disposed on the outer surface of the needle 20.

As shown in FIG. 5, the first insulating base material 71 is arranged only on a part of the outer surface of the needle 20 and is configured not to cover the entire outer surface of the needle 20. As shown in FIG. 8, the second insulating base material 72 is arranged only on a part of the outer surface of the needle 20 and is configured not to cover the entire outer surface of the needle 20.

As shown in FIGS. 5 to 11, the first insulating base material 71 and the second insulating base material 72 are formed in a cylindrical shape. Preferably, the needle 20 is disposed within the lumen of the lumen 72.

As shown in FIGS. 5 to 11, when the hole 24 is formed in the portion of the needle 20 where the first insulating base material 71 or the second insulating base material 72 is arranged, the hole 24 of the needle 20 and It is preferable that the communicating holes 74 are formed in the first insulating base material 71 or the second insulating base material 72. Although not shown, the hole 24 may be formed in a portion of the needle 20 where the first insulating base material 71 and the second insulating base material 72 are not arranged.

As shown in FIGS. 12 to 14, the hole 24 may be formed in the needle 20 on which the first insulating base material 71 and the second insulating base material 72 are not arranged.

The counter electrode 30 is not particularly limited as long as it has a shape that can be placed on the body surface of the person to be treated, but for example, a plate-shaped, sheet-shaped, or pad-shaped electrode can be used.

Examples of the counter electrode 30 include an electrode pad that can be attached to the body surface of the subject. The electrode pad may have a conductive layer and an adhesive gel layer or solid gel layer disposed on the conductive layer. As the conductive layer, it is preferable to use a conductive resin or a metal such as gold, silver, copper, platinum, platinum-iridium alloy, stainless steel, or tungsten.

The counter electrode 30 can be placed, for example, on the back of the subject.

The measuring device 40 is not particularly limited as long as it can measure the electrical resistance between the needle 20 and the counter electrode 30, and any known measuring device can be used.

As shown in FIG. 1, the needle system 1 may further include a power supply 53 for supplying electrical current to pass the electrical current between the needle 20 and the counter electrode 30.

Although not shown in detail, the needle 20 may be connected to a first conducting wire 61, and the first conducting wire 61 may be connected to a power supply device 53. Further, the power supply device 53 may be connected to a second conducting wire 62, and the second conducting wire 62 may be connected to the measuring device 40. The counter electrode 30 is connected to a third conducting wire 63, and the third conducting wire 63 may be connected to the measuring device 40.

1: Needle system 10: Resin tube 11: Lumen 20: Needle 21: Lumen 22: Opening 23: Side wall 24: Hole 30: Counter electrode 40: Measuring device 51: First handle 52: Second handle 53: Power supply device 54: Liquid supply device 61: First conducting wire 62: Second conducting wire 63: Third conducting wire 71: First insulating base material 72: Second insulating base material 74: Hole

Claims (8)

a resin tube having a lumen extending in the longitudinal direction;
a needle made of a conductive material, disposed in the inner lumen of the resin tube so as to be movable relative to the resin tube, and punctured into an internal organ;
a counter electrode placed on the body surface;
A needle system comprising: a measuring device that measures electrical resistance between the needle and the counter electrode when a current is passed between the needle and the counter electrode. The needle system of claim 1, wherein the needle has a lumen extending in the longitudinal direction. 3. The needle system of claim 2, wherein the distal end of the needle has an opening that communicates with the lumen of the needle. the needle has a sidewall forming a lumen of the needle;
4. The needle system of claim 2 or 3, wherein a hole is formed in a distal portion of the needle and in a side wall of the needle that communicates with the lumen of the needle. A plurality of holes are formed on the side wall of the needle,
5. The needle system of claim 4, wherein the plurality of holes are aligned in the longitudinal direction. The needle system of claim 1, wherein the needle is constructed entirely of metal. The needle system of claim 1, wherein a first insulating substrate is disposed on an outer surface of the needle, including a distal end of the needle. 8. The needle system of claim 7, wherein a second insulating substrate is disposed on an outer surface of the needle proximal to a proximal end of the first insulating substrate.

Images