JP2023106120A - Agrochemical composition - Google Patents

Abstract

To provide a composition comprising a compound represented by the formula (I) as an agrochemical active ingredient, with the particles of the compound suspended in water, wherein it is possible to inhibit the growth of the particle size of the compound in the water over time.SOLUTION: Provided is a composition which comprises a compound represented by the formula (I), at least one compound represented by the formula (II) (excluding the compound represented by the formula (I)), a surfactant, a thickener, a preservative, and water. The content of the compound represented by the formula (II) is 0.02 pt.mass or more and 2.2 pts.mass or less relative to 100 pts.mass of the compound represented by the formula (I).SELECTED DRAWING: None

Description

The present invention relates to compositions containing pesticidally active compounds.

WO 2005/121104 (Patent Document 1) describes pyridazine compounds having plant disease control activity.

WO2005/121104

Aqueous suspension concentrates (also called SC) are known as one of the forms of agrochemical formulations, in which particles of a solid agrochemical active ingredient are suspended in water.

An object of the present invention is to provide a composition containing a pyridazine compound represented by the formula (I) described below as an agrochemically active ingredient, particles of the pyridazine compound being suspended in water, An object of the present invention is to provide a composition capable of suppressing growth of particle size over time.

で表される化合物、式（ＩＩ）

〔式中、
－Ｔ－Ｌ－は、－Ｃ（Ｘ）＝Ｎ－＊又は－Ｃ（Ｏ）－ＮＨ－＊を表し、
＊は、Ｌが結合する窒素原子との結合位置を表し、
Ｘは、塩素原子又は［４－（２，６－ジフルオロフェニル）－５－フェニル－６－メチルピリダジン－３－イル］オキシ基を表し、
Ｒ^１は、フェニル基、２－フルオロフェニル基、又は２，６－ジフルオロフェニル基を表し、
Ｒ^２は、水素原子又はフェニル基を表し、
Ｒ^３は、メチル基又はベンゾイル基を表す。〕
で表される少なくとも一つの化合物（ただし、前記式（Ｉ）で表される化合物は除く。）、界面活性剤、増粘剤、防腐剤、及び水を含有し、
前記式（ＩＩ）で表される化合物の含有量が、前記式（Ｉ）で表される化合物１００質量部に対して０．０２質量部以上２．２質量部以下である組成物。
［２］ 前記組成物１００質量部に対して、前記式（Ｉ）で表される化合物を５質量部以上６０質量部以下、前記界面活性剤を１質量部以上２０質量部以下、前記増粘剤を０．０１質量部以上１質量部以下、前記防腐剤を０．０１質量部以上１質量部以下、及び前記水を１５質量部以上９０質量部以下含有する［１］に記載の組成物。
［３］ 前記組成物１００質量部に対して、前記式（Ｉ）で表される化合物を１５質量部以上４５質量部以下、前記界面活性剤を５質量部以上１５質量部以下、前記増粘剤を０．１質量部以上０．５質量部以下、前記防腐剤を０．１質量部以上０．５質量部以下、及び前記水を３５質量部以上７９質量部以下含有する［１］に記載の組成物。
［４］ 式（Ｉ）

で表される化合物、及び式（ＩＩ－１）

で表される化合物を含有する組成物。
［５］ 界面活性剤、増粘剤、防腐剤、及び水をさらに含有する［４］に記載の組成物。 The present invention provides compositions shown below.
[1] Formula (I)

a compound of the formula (II)

[In the formula,
-T-L- represents -C(X)=N-* or -C(O)-NH-*,
* represents the bonding position with the nitrogen atom to which L is bonded,
X represents a chlorine atom or a [4-(2,6-difluorophenyl)-5-phenyl-6-methylpyridazin-3-yl]oxy group;
R ¹ represents a phenyl group, a 2-fluorophenyl group or a 2,6-difluorophenyl group,
R ² represents a hydrogen atom or a phenyl group,
^R3 represents a methyl group or a benzoyl group. ]
At least one compound represented by (excluding the compound represented by the formula (I)), a surfactant, a thickener, a preservative, and water,
A composition in which the content of the compound represented by the formula (II) is 0.02 parts by mass or more and 2.2 parts by mass or less per 100 parts by mass of the compound represented by the formula (I).
[2] With respect to 100 parts by mass of the composition, 5 parts by mass or more and 60 parts by mass or less of the compound represented by the formula (I), 1 part by mass or more and 20 parts by mass or less of the surfactant, and the thickening 0.01 parts by mass to 1 part by mass of the agent, 0.01 parts by mass to 1 part by mass of the preservative, and 15 parts by mass to 90 parts by mass of the water. .
[3] With respect to 100 parts by mass of the composition, 15 parts by mass or more and 45 parts by mass or less of the compound represented by the formula (I), 5 parts by mass or more and 15 parts by mass or less of the surfactant, and the thickening [1] containing 0.1 to 0.5 parts by mass of the agent, 0.1 to 0.5 parts by mass of the preservative, and 35 to 79 parts by mass of the water The described composition.
[4] Formula (I)

A compound represented by the formula (II-1)

A composition containing a compound represented by
[5] The composition of [4], further comprising a surfactant, thickener, preservative and water.

A composition containing a compound represented by formula (I) as an agrochemical active ingredient, wherein particles of the compound are suspended in water, wherein the growth of the particle size of the compound in water over time is suppressed. can be provided.

The composition according to the present invention (hereinafter also referred to as "this composition") is
(a) a compound represented by the above formula (I) (hereinafter also referred to as "compound (I)"),
(b) at least one of the compounds represented by the above formula (II) (hereinafter also referred to as "compound (II)");
(c) a surfactant;
(d) a thickening agent;
(e) preservatives; and (f) water. Compound (I), which is an agriculturally active ingredient in the present composition, is preferably dispersed in water in a solid state. Compound (II) is also preferably dispersed in water in a solid state.

The present composition can suppress growth of particle size of compound (I) over time, and is excellent in stability over time. Grain size growth is due to crystal growth.
The components that the present composition contains or may contain are described in detail below.

(a) Compound (I)
Compound (I) is a known compound described in Patent Document 1, for example, and can be produced by the method described in the same document.

The content of compound (I) is usually 1 part by mass or more and 60 parts by mass or less, preferably 5 parts by mass or more and 60 parts by mass or less, more preferably 10 parts by mass or more and 50 parts by mass or less, relative to 100 parts by mass of the present composition. Below, more preferably 15 parts by mass or more and 45 parts by mass or less. When the content of compound (I) is within the above range, it is easy to achieve both sufficient plant disease control efficacy and high stability over time.

で表される化合物である。
本組成物は、化合物（ＩＩ）を１種又は２種以上含有することができる。 (b) Compound (II)
Compound (II) is a compound having a chemical structure different from that of compound (I) and represented by formula (II)

It is a compound represented by
The composition may contain one or more compounds (II).

In formula (II), -T-L- represents -C(X)=N-* or -C(O)-NH-*, * represents the bonding position with the nitrogen atom to which L binds . X represents a chlorine atom or a [4-(2,6-difluorophenyl)-5-phenyl-6-methylpyridazin-3-yl]oxy group.
R ¹ represents a phenyl group, a 2-fluorophenyl group, or a 2,6-difluorophenyl group.
^R2 represents a hydrogen atom or a phenyl group.
^R3 represents a methyl group or a benzoyl group.

Specific examples of compound (II) are shown in Tables 1 to 3. In the table, X ¹ represents a [4-(2,6-difluorophenyl)-5-phenyl-6-methylpyridazin-3-yl]oxy group. -CH ₃ is a methyl group, -C ₆ H ₅ is a phenyl group, -C ₆ H ₄ F is a 2-fluorophenyl group, -C ₆ H ₃ F ₂ is a 2,6-difluorophenyl group, -C( O)--CH ₃ represents a benzoyl group.

From the viewpoint of suppressing the growth of particle size of compound (I) over time, in one preferred embodiment, the present composition comprises compound (II-1), compound (II-5), compound (II-9) , compound (II-16), compound (II-20), compound (II-24), compound (II-28) and compound (II-32) containing at least one compound selected from the group consisting of .
From the same point of view, in another preferred embodiment, the present composition is selected from the group consisting of compound (II-1), compound (II-16), compound (II-20) and compound (II-24) It contains at least one compound.

Compound (II-1), compound (II-16), compound (II-20) and compound (II-24) are represented by formula (II-1), formula (II-16) and formula (II-20), respectively. ) and a compound represented by formula (II-24).

Compound (II-24) has tautomers. As used herein, compound (II-24) also includes the enol form represented by the following formula.

Compound (II) can be produced by the method described in Patent Document 1 or according to it. Compound (II-1) can be produced, for example, by the method described in JP-A-2020-66608.

In a preferred embodiment, the composition contains the following compound as compound (II).
Embodiment A: Compound (II-1)
Embodiment B: Compound (II-20)
Embodiment C: Compound (II-24)
Embodiment D: Compound (II-1) and Compound (II-20)
Embodiment E: Compound (II-1) and Compound (II-24)
Embodiment F: Compound (II-1), Compound (II-20) and Compound (II-24)
Embodiment G: Compound (II-1), Compound (II-16), Compound (II-20) and Compound (II-24)

The content of compound (II) in the present composition is 0.02 parts by mass or more relative to 100 parts by mass of compound (1) from the viewpoint of suppressing the growth of the particle size of compound (I) over time, It is preferably 0.05 parts by mass or more, more preferably 0.10 parts by mass or more, even more preferably 0.15 parts by mass or more, and even more preferably 0.18 parts by mass or more.
The content of compound (II) is 2.2 parts by mass or less, preferably 2.1 parts by mass or less, more preferably 2.0 parts by mass or less, in consideration of the plant disease control efficacy of the present composition. 1.9 parts by mass or less, 1.8 parts by mass or less, 1.5 parts by mass or less, 1.2 parts by mass or less, 1.0 parts by mass or less, 0.8 parts by mass or less, 0.6 parts by mass Below, it may be 0.4 parts by mass or less or 0.3 parts by mass or less.

The content of compound (II) is the total content when two or more compounds (II) are contained in the present composition. The same applies to other components described later that the present composition contains or may contain, and when two or more of these components are contained, the content of the components is the total content thereof unless otherwise specified.

(c) Surfactant The composition contains one or more surfactants. Surfactants include anionic surfactants, nonionic surfactants, cationic surfactants and amphoteric surfactants. The composition preferably contains a surfactant selected from the group consisting of an anionic surfactant and a nonionic surfactant, more preferably an anionic surfactant.

Preferred anionic surfactants are sulfonates, sulfates, phosphates, carboxylates and mixtures thereof.
Examples of sulfonates include naphthalenesulfonates and formaldehyde condensates thereof, alkylbenzenesulfonates, alkylnaphthalenesulfonates, alkyldiphenylether disulfonates, α-olefinsulfonates, ligninsulfonates, and polyoxyethylene. Alkylphenyl ether sulfonates as well as dialkyl sulfosuccinates are mentioned.
Sulfate ester salts include, for example, alkyl sulfate ester salts, polyoxyethylene alkyl ether sulfate ester salts and polyoxyethylene alkylphenyl ether sulfate ester salts.
Phosphate salts include, for example, polyoxyethylene alkylaryl ether phosphate salts and polyoxyethylene tristyrylphenyl ether phosphate salts.
Carboxylate salts include, for example, fatty acid salts and polycarboxylates.

Nonionic surfactants include, for example, polyoxyethylene alkyl ether, polyoxypropylene alkyl ether, polyoxyethylene polyoxypropylene alkyl ether, polyoxyethylene distyrylphenyl ether, polyoxyethylene tristyrylphenyl ether, sucrose fatty acid esters, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, glycerin fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene alkylamines, alkyl alkanolamides, polyoxyethylene polyoxypropylene block copolymers, alkyl polyglycosides and Acrylic copolymers are mentioned.

Cationic surfactants include, for example, alkylamine salts and quaternary ammonium salts.
Amphoteric surfactants include, for example, alkylbetaines.

The content of the surfactant is usually 0.5 parts by mass or more and 30 parts by mass or less, preferably 1 part by mass or more and 20 parts by mass or less, more preferably 3 parts by mass or more and 20 parts by mass, relative to 100 parts by mass of the present composition. parts or less, more preferably 5 parts by mass or more and 15 parts by mass or less.

(d) Thickener The composition contains one or more thickeners. Examples of thickening agents include natural polysaccharides such as xanthan gum, rhamsan gum, locust bean gum, guar gum, carrageenan, welan gum, alginic acid, alginates, and tragacanth gum; mineral powders such as fumed silica; and alumina sols. As these thickeners, commercially available products can be used as they are. Examples of such commercially available products include xanthan gum Kelzan (CP Kelco trade name) and Kelzan S PLUS (CP Kelco trade name), aluminum silicate Veegum R (Vanderbilt trade name), and dry silica. Aerosil 200 (trade name of Nippon Aerosil Co., Ltd.) can be mentioned.

The content of the thickener is usually 0.01 to 1 part by mass, preferably 0.05 to 0.5 part by mass, more preferably 0.05 part by mass to 1 part by mass, based on 100 parts by mass of the present composition. It is 1 mass part or more and 0.5 mass part or less.

(e) Preservatives The composition contains one or more preservatives. Examples of preservatives include p-hydroxybenzoic acid esters, salicylic acid derivatives, and isothiazolinone preservatives.

The content of the preservative is usually 0.01 parts by mass or more and 1 part by mass or less, preferably 0.05 parts by mass or more and 0.5 parts by mass or less, more preferably 0.1 part by mass, per 100 parts by mass of the present composition. It is 0.5 parts by mass or more and 0.5 parts by mass or less.

(f) Water The composition contains water. Water includes deionized water, tap water and ground water.

The content of water is usually 15 parts by mass or more and 98 parts by mass or less, preferably 15 parts by mass or more and 90 parts by mass or less, more preferably 25 parts by mass or more and 85 parts by mass or less, and further It is preferably 35 parts by mass or more and 79 parts by mass or less.

(g) Other Ingredients The composition may contain other ingredients than those described above, if necessary.
Other ingredients include, for example, agricultural chemical active ingredients other than those mentioned above, antifreezing agents, antifoaming agents, and other formulation adjuvants.

Antifreeze agents include ethylene glycol, propylene glycol, urea and glycerin. Two or more antifreeze agents may be used. The content of the antifreezing agent is usually 1 part by mass or more and 10 parts by mass or less, preferably 2 parts by mass or more and 8 parts by mass or less, relative to 100 parts by mass of the present composition.

Antifoaming agents include silicone antifoaming agents. Two or more antifoaming agents may be used. The content of the antifoaming agent is usually 0.01 to 1 part by mass, preferably 0.05 to 0.5 part by mass, per 100 parts by mass of the present composition.

The total content of compound (I), compound (II), surfactant, thickener, preservative and water in the present composition is preferably 60% by mass or more, more preferably 70% by mass or more, and still more preferably 80% by mass. % by mass or more, and more preferably 85% by mass or more.

(h) Preparation method of the present composition The present composition can be prepared by mixing predetermined components by a conventionally known method for preparing SC. Examples of preparation methods are given below.

First, compound (I), compound (II), a surfactant, water, and, if necessary, adjuvants for formulation (antifoaming agent, etc.) are mixed, and the resulting suspension is subjected to pulverization treatment. to obtain a pulverized suspension (first step). Next, a thickening agent, a preservative, and if necessary, other formulation adjuvants (antifreeze agent, etc.) and water are added to the pulverized suspension obtained and mixed to obtain the present composition (Second process). In the second step, a thickening agent, a preservative, and optionally other formulation adjuvants (such as an antifreeze agent) and water are mixed in advance to prepare a thickened liquid, and this thickened liquid and the pulverized suspension are mixed in advance. may be mixed to obtain the present composition.

In the present composition immediately after preparation, the particle size of the solid particles is usually 0.1 μm or more, preferably 0.5 μm or more, more preferably 1.0 μm or more. The particle size is usually 5 μm or less, and may be 4 μm or less or 3 μm or less.

The particle size as used herein means a volume median diameter (a particle size with a cumulative frequency of 50% in a volume-based frequency distribution) measured by wet measurement using a laser diffraction particle size distribution analyzer. Wet measurement refers to measurement by dispersing the composition sample in water.

According to the present composition, growth of particle size of compound (I) over time can be suppressed. According to the present composition, the grain growth rate represented by the following formula when stored at a temperature of 40° C. for one month is, for example, 40% or less, preferably 35% or less, more preferably 30% or less, and still more preferably It can be suppressed to 25% or less, even more preferably 20% or less, particularly preferably 15% or less, and most preferably 10% or less.
Particle growth rate (%) = 100 x (particle size after storage at 40°C for 1 month - particle size immediately after preparation)/particle size immediately after preparation

The present composition can suppress the growth of the particle size of compound (I) in water over time and is excellent in stability over time, so that it can be suitably used as an aqueous suspension preparation.

The present invention also relates to compositions containing compound (I) and compound (II-1). The composition can be used, for example, for the preparation of the present composition (aqueous suspension formulation) or other formulation forms of pesticidal formulations. The above descriptions are cited for the compound (I) and compound (II-1) contained in the composition and their content ratio.

The composition containing compound (I) and compound (II-1) may further contain surfactants, thickeners, preservatives and water. The composition may further contain other formulation adjuvants such as antifreeze agents, antifoam agents and the like. Surfactants, thickeners, preservatives, antifreeze agents, antifoaming agents, water, and their contents are referred to above. A composition containing these can be used as an agricultural chemical formulation by formulating.

(i) Use of the present composition By applying the present composition to plants or their growing environment, plant diseases caused by phytopathogenic microorganisms can be controlled. The user typically applies the compositions from a knapsack sprayer, spray tank, spray plane, or irrigation system. Generally, the composition is diluted with water to the desired application concentration to form a spray solution. Generally, 20 to 2000 L, preferably 50 to 400 L of spray liquid are applied per hectare.

The amount of application of the present composition is appropriately adjusted depending on the content of pesticidal active ingredients contained in the present composition, the type of plant, the type and frequency of plant disease, the time of application, the method of application, the place of application, weather conditions, etc. be.

Plant diseases that can be controlled by application of the present composition include the following. Parentheses indicate the scientific name of the pathogenic microorganism that causes the disease.

Rice diseases: Pyricularia oryzae, Cochliobolus miyabeanus, Rhizoctonia solani, Gibberella fujikuroi, Sclerophthora macrospora, Sclerophthora macrospora, and Epicoccum nigrum, Trichoderma viride, Rhizopus oryzae;
Wheat diseases: Powdery mildew (Blumeria graminis), Fusarium graminearum, Fusarium avenaceum, Fusarium culmorum, Microdochium nivale, Yellow rust (Puccinia striiformis), Black rust (Puccinia graminis), Red rust (Puccinia recondita) ), red snow rot (Microdochium nivale, Microdochium majus), snow rot (Typhula incarnata, Typhula ishikariensis), naked smut (Ustilago tritici), raw smut (Tilletia caries, Tilletia controversa), eye spot Pseudocercosporella herpotrichoides, Septoria tritici, Stagonospora nodorum, Pyrenophora tritici-repentis, Rhizoctonia solani, Gaeumannomyces graminis , rice blast (Pyricularia graminis-tritici);
Barley diseases: Powdery mildew (Blumeria graminis), Fusarium graminearum, Fusarium avenaceum, Fusarium culmorum, Microdochium nivale, Yellow rust (Puccinia striiformis), Black rust (Puccinia graminis), Small rot (Puccinia) hordei), Naked smut (Ustilago nuda), Rhynchosporium secalis, Pyrenophora teres, Cochliobolus sativus, Pyrenophora graminea, Ramularia collo-cygni ), seedling wilt caused by Rhizoctonia (Rhizoctonia solani);
Corn diseases: Puccinia sorghi, Puccinia polysora, Setosphaeria turcica, Physopella zeae, Cochliobolus heterostrophus, Colletotrichum graminicola ), gray leaf spot (Cercospora zeae-maydis), brown spot (Kabatiella zeae), Phaeosphaeria leaf spot (Phaeosphaeria maydis), Diplodia (Stenocarpella maydis, Stenocarpella macrospora), Stokerot disease (Fusarium graminearum, Fusarium verticilioides, Colletotrichum graminicola, Ustilago maydis, Physoderma maydis;
Cotton diseases: Colletotrichum gossypii, Ramularia areola, Alternaria macrospora, Alternaria gossypii, Black root rot (Thielaviopsis basicola);
Coffee diseases: rust (Hemileia vastatrix), leaf spot (Cercospora coffeicola);
Diseases of oilseed rape: Sclerotinia sclerotiorum, Alternaria brassicae, Phoma lingam, light leaf spot (Pyrenopeziza brassicae);
Sugar cane diseases: rust (Puccinia melanocephela, Puccinia kuehnii), smut (Ustilago scitaminea);
sunflower diseases: rust (Puccinia helianthi), downy mildew (Plasmopara halstedii);
Citrus diseases: Diaporthe citri, Elsinoe fawcetti, Penicillium digitatum, Penicillium italicum, Phytophthora parasitica, Phytophthora citrophthora, Aspergillus niger ;
Apple diseases: Monilinia mali, rot (Valsa ceratosperma), powdery mildew (Podosphaera leucotricha), leaf spot (Alternaria alternata apple pathotype), scab (Venturia inaequalis), anthracnose (Glomerella cingulata, Colletotrichum) acutatum), Diplocarpon mali, Botryosphaeria berengeriana, Phytophtora cactorum, Gymnosporangium juniperi-virginianae, Gymnosporangium yamadae;
pear diseases: Venturia nashicola, Venturia pirina, Alternaria alternata Japanese pear pathotype, Gymnosporangium haraeanum;
Peach diseases: Monilinia fructicola, Cladosporium carpophilum, Phomopsis sp., Taphrina deformans;
Grape diseases: black rot (Elsinoe ampelina), late rot (Glomerella cingulata, Colletotrichum acutatum), powdery mildew (Uncinula necator), rust (Phakopsora ampelopsidis), blacklot (Guignardia bidwellii), downy mildew ( Plasmopara viticola);
Diseases of oysters: anthracnose (Gloeosporium kaki, Colletotrichum acutatum), defoliation (Cercospora kaki, Mycosphaerella nawae);
Cucurbit diseases: Colletotrichum lagenarium, Sphaerotheca fuliginea, Didymella bryoniae, Corynespora cassiicola, Fusarium oxysporum, Pseudoperonospora cubensis ), late blight (Phytophthora capsici), seedling blight (Pythium sp.);
Tomato diseases: Alternaria solani, Cladosporium fulvum, Pseudocercospora fuligena, Phytophthora infestans, Leveillula taurica;
Eggplant diseases: Phomopsis vexans, powdery mildew (Erysiphe cichoracearum);
Diseases of cruciferous vegetables: black spot (Alternaria japonica), white spot (Cercosporella brassicae), clubroot (Plasmodiophora brassicae), downy mildew (Peronospora parasitica), white rust (Albugo candida);
Diseases of Allium: Rust (Puccinia allii);
Soybean diseases: purpura (Cercospora kikuchii), black spot (Elsinoe glycines), black spot (Diaporthe phaseolorum var. sojae), rust (Phakopsora pachyrhizi), brown spot (Corynespora cassiicola), anthracnose (Colletotrichum glycines) , Colletotrichum truncatum), leaf rot (Rhizoctonia solani), brown spot (Septoria glycines), leaf spot (Cercospora sojina), sclerotinia (Sclerotinia sclerotiorum), powdery mildew (Microsphaera diffusa), stem blight (Phytophthora sojae) , downy mildew (Peronospora manshurica), sudden death (Fusarium virguliforme), black root rot (Calonectria ilicicola), Diaporthe/Phomopsis complex (Diaporthe longicolla);
Common bean diseases: Sclerotinia sclerotiorum, Uromyces appendiculatus, Phaeoisariopsis griseola, Colletotrichum lindemuthianum, Fusarium solani;
Peanut diseases: black stain (Cercospora personata), brown spot (Cercospora arachidicola), white silk (Sclerotium rolfsii), black root rot (Calonectria ilicicola);
Pea diseases: powdery mildew (Erysiphe pisi), root rot (Fusarium solani);
Potato diseases: Alternaria solani, Phytophthora infestans, Phytophthora erythroseptica, Spongospora subterranea f. sp. subterranea, Verticillium albo-atrum, Verticillium dahliae, Verticillium nigrescens), dry rot (Fusarium solani), carcinoma (Synchytrium endobioticum);
Diseases of strawberries: powdery mildew (Sphaerotheca humuli);
Tea diseases: Exobasidium reticulatum, Elsinoe leucospira, Pestalotiopsis sp., Colletotrichum theae-sinensis;
Tobacco diseases: Alternaria longipes, Colletotrichum tabacum, Downy mildew (Peronospora tabacina), Phytophthora nicotianae;
Sugar beet diseases: Cercospora beticola, Thanatephorus cucumeris, Thanatephorus cucumeris, Aphanomyces cochlioides, Uromyces betae;
diseases of roses: scab (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa);
Chrysanthemum diseases: brown spot (Septoria chrysanthemi-indici), white rust (Puccinia horiana);
Onion diseases: white spot blight (Botrytis cinerea, Botrytis byssoidea, Botrytis squamosa), gray rot (Botrytis allii), sclerotium rot (Botrytis squamosa);
various crop diseases: Botrytis cinerea, Sclerotinia sclerotiorum, Pythium aphanidermatum, Pythium irregulare, Pythium ultimum;
Diseases of radish: Alternaria brassicicola;
Diseases of turfgrass: dollar spot (Sclerotinia homoeocarpa), brown patch, large patch (Rhizoctonia solani), red scorch (Pythium aphanidermatum);
Banana diseases: sigatoka (Mycosphaerella fijiensis, Mycosphaerella musicola);
Diseases of lentils: Ascochyta lentis;
Diseases of chickpeas: Ascochyta disease (Ascochyta rabiei);
Diseases of peppers: Colletotrichum scovillei;
mango diseases: Colletotrichum acutatum;
Fruit tree diseases: Roselinia necatrix, Helicobasidium mompa;
Post-harvest fruit diseases such as apples and pears: Mucor piriformis;
Seed diseases or early growth diseases caused by Aspergillus, Penicillium, Fusarium, Gibberella, Tricoderma, Thielaviopsis, Rhizopus, Mucor, Corticium, Phoma, Rhizoctonia, Diplodia, etc.;
Viral diseases: Big Vein disease of lettuce mediated by Olpidium brassicae, viral diseases of various crops mediated by Polymyxa genera (e.g. Polymyxa betae and Polymyxa graminis);
Diseases caused by bacteria: Burkholderia plantarii in rice, Pseudomonas syringae pv. Lachrymans in cucumber, Ralstonia solanacearum in eggplant, Xanthomonas citri in citrus ), Chinese cabbage soft rot (Erwinia carotovora), potato scab (Streptomyces scabiei), maize Goss's wilt (Clavibacter michiganensis), Pierce disease (Xylella fastidiosa) of grapes, olives, peaches, etc., apples, peaches, cherries Root cancer (Agrobacterium tumefaciens) of Rosaceae plants such as.

EXAMPLES The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these examples.

<Comparative Example 1>
Obtained by mixing 35.0 parts by mass of compound (I), 10.0 parts by mass of surfactant (40% by mass of active ingredient), 0.2 parts by mass of antifoaming agent, and 34.8 parts by mass of ion-exchanged water Glass beads were added to the resulting mixture, and the mixture was wet pulverized by stirring using a three-one motor (manufactured by Yamato Scientific Co., Ltd.) to obtain a pulverized suspension (80 parts by mass).
In addition, 1.2 parts by mass of thickener 1, 2.4 parts by mass of thickener 2, and 2.0 parts by mass of preservative were added to 194.4 parts by mass of ion-exchanged water, and the resulting thickened liquid was continuously stirred for 2 hours. (200 parts by mass) was obtained.
Then, 80 parts by mass of the pulverized suspension and 20 parts by mass of the thickened liquid were mixed to obtain a composition.

<Comparative Examples 2 and 3 and Examples 1 to 9>
A pulverized suspension and a thickened liquid were prepared according to the method described in Comparative Example 1 so as to have the compositions shown in Table 4, and mixed to obtain respective compositions. Compound (II-1), compound (II-16), compound (II-20), compound (II-24), compound (III) and xylene were prepared to be contained in the pulverized suspension. In Table 4, the unit for the amount of each compounding component is parts by mass.

(Evaluation of particle growth rate)
For each composition, the particle size (as defined above) was measured immediately after preparation and after storage at 40° C. for 1 month, and the particle size growth rate was calculated by the following formula. The particle size was measured by wet measurement using a laser diffraction particle size distribution analyzer (Mastersizer 2000, manufactured by Malvern). Table 4 shows the results. "After storage" in the table means after storage at 40°C for 1 month.
Particle growth rate (%) = 100 x (particle size after storage at 40°C for 1 month - particle size immediately after preparation)/particle size immediately after preparation

Details of the ingredients listed in Table 4 are as follows.
[1] Surfactant: a mixture of 40% by mass of polyoxyethylene tristyrylphenyl ether phosphate potassium salt and 60% by mass of propylene glycol (Soprofol FLK, manufactured by Solvay Nikka Co., Ltd.)
[2] Antifoaming agent: Silicone antifoaming agent (KS-538, manufactured by Shin-Etsu Chemical Co., Ltd.)
[3] Thickener 1: xanthan gum (Kelzan S Plus, manufactured by CP Kelco)
[4] Thickener 2: Magnesium aluminum silicate (Beegum R, manufactured by Vanderbilt)
[5] Preservative: Preservative containing 1,2-benzisothiazolin-3-one as an active ingredient (Proxel GXL (S), manufactured by Lonza)
[6] Compound (III): a compound represented by the following formula

Claims (5)

Formula (I)

a compound of the formula (II)

[In the formula,
-T-L- represents -C(X)=N-* or -C(O)-NH-*,
* represents the bonding position with the nitrogen atom to which L is bonded,
X represents a chlorine atom or a [4-(2,6-difluorophenyl)-5-phenyl-6-methylpyridazin-3-yl]oxy group;
R ¹ represents a phenyl group, a 2-fluorophenyl group or a 2,6-difluorophenyl group,
R ² represents a hydrogen atom or a phenyl group,
^R3 represents a methyl group or a benzoyl group. ]
At least one compound represented by (excluding the compound represented by the formula (I)), a surfactant, a thickener, a preservative, and water,
A composition in which the content of the compound represented by the formula (II) is 0.02 parts by mass or more and 2.2 parts by mass or less per 100 parts by mass of the compound represented by the formula (I). Per 100 parts by mass of the composition, 5 parts by mass or more and 60 parts by mass or less of the compound represented by the formula (I), 1 part by mass or more and 20 parts by mass or less of the surfactant, and 0 part by mass of the thickener. 01 to 1 part by weight, 0.01 to 1 part by weight of the preservative, and 15 to 90 parts by weight of the water. Per 100 parts by mass of the composition, 15 parts by mass or more and 45 parts by mass or less of the compound represented by the formula (I), 5 parts by mass or more and 15 parts by mass or less of the surfactant, and 0 parts by mass of the thickener. .1 to 0.5 parts by mass, 0.1 to 0.5 parts by mass of the preservative, and 35 to 79 parts by mass of the water. thing. Formula (I)

A compound represented by the formula (II-1)

A composition containing a compound represented by 5. The composition of claim 4, further comprising surfactants, thickeners, preservatives, and water.