JP2023069593A - Oil-in-water type emulsion composition - Google Patents

Abstract

To provide an oil-in-water type emulsion composition having good storage stability, thick feeling and smooth finger slide during application and excellent skin elasticity after application in an emulsion composition comprising a tocopheryl phosphate ester and/or a salt thereof.SOLUTION: There is provided an oil-in-water type emulsion composition which comprises the following components (A) to (E): (A) a tocopheryl phosphate ester and/or a salt thereof, (B) an acyl methyl taurate, (C) a higher alcohol having 12 to 22 carbon atoms, (D) a higher fatty acid having 12 to 22 carbon atoms and (E) a glycerol monoalkyl ether and has good storage stability, thick feeling and smooth finger slide during application and excellent skin elasticity after application.SELECTED DRAWING: None

Description

The present invention provides an emulsified composition containing a tocopheryl phosphate and/or a salt thereof, which has good storage stability, provides a deep richness during application, smooth finger sliding, and a firm skin feel after application. It relates to an excellent oil-in-water emulsion composition.

Tocopheryl phosphate and/or salts thereof are known to exhibit physiological activity equal to or greater than that of tocopherol when metabolized in vivo. It has been reported that when these are blended in external preparations for the skin, they exhibit anti-wrinkle effects (Patent Document 1), whitening effects (Patent Document 2), active oxygen scavenging effects (Patent Document 3), and the like. Moreover, since tocopheryl phosphate and/or its salt is an anionic amphipathic substance, a technique for functioning as an emulsifier has also been studied (Patent Document 4).

However, when a tocopheryl phosphate and/or a salt thereof is contained in an emulsified system, there is a problem that coagulation and sedimentation occur, impairing the storage stability of the formulation. To address this problem, a technique has been proposed in which a tocopheryl phosphate and/or a salt thereof, a dextrin fatty acid ester, an oily component that is liquid at 25°C, and an oily component that is solid and/or semi-solid at 25°C are incorporated. (Patent Document 5). By using this technique, it is possible to obtain an emulsified composition that stably contains a tocopheryl phosphate and/or a salt thereof and that is excellent in firmness and moistness. However, in this technique, the dextrin fatty acid ester is an essential component, and the formulation is limited, and when the higher alcohol and/or the higher fatty acid are contained in a large amount, the emulsification may be deteriorated.

For emulsified compositions containing tocopheryl phosphate and/or salts thereof and higher alcohols and/or higher fatty acids, a technique for incorporating ceramide, tocopheryl phosphate and/or salts thereof, and batyl alcohol (Patent Document 6 ) in the examples. The emulsified composition is stable at 40° C. for one month as described, but in some cases the long-term storage stability is not sufficient. In addition, no consideration has been given to the profound richness upon application, smooth finger slippage, and firmness of the skin after application.

Higher alcohols and higher fatty acids in the oil-in-water emulsion composition form a periodic structure at the interface between the water phase and the oil phase, thereby increasing the viscosity of the emulsion composition and imparting a rich richness during application. In recent years, there is a tendency to prefer a rich and rich feel that brings a luxurious feeling when applied, so in an oil-in-water emulsion composition containing a higher alcohol and / or a higher fatty acid, tocopheryl phosphate and / or its A further technique for stably containing a salt has been desired.

JP-A-2008-007428 JP 2004-026817 A Japanese Patent Application Laid-Open No. 2006-232767 Japanese Patent No. 3712673 Japanese Patent Application Laid-Open No. 2020-203860 JP 2011-016761 A

An oil-in-water emulsified composition containing a tocopheryl phosphate and/or a salt thereof, which has good storage stability, has a profound body during application, smooth finger sliding, and excellent skin firmness after application. An object of the present invention is to provide a type emulsion composition.

As a result of intensive studies on the above problems, the present inventors have found that tocopheryl phosphate and/or its salt, acylmethyl taurate, higher alcohol having 12 to 22 carbon atoms, and 12 to 22 carbon atoms. The inventors have found that an oil-in-water emulsified composition containing a higher fatty acid and glycerin monoalkyl ether can solve the above problems, and have completed the present invention.

That is, the present invention
(A) Tocopheryl phosphate and/or salt thereof (B) Acylmethyl taurine salt (C) Higher alcohol having 12 to 22 carbon atoms (D) Higher fatty acid having 12 to 22 carbon atoms (E) Glycerol monoalkyl An oil-in-water emulsion composition characterized by containing an ether is provided.

The present invention also provides an oil-in-water emulsion composition, wherein the component (B) is sodium stearoylmethyltaurate.

The present invention also provides an oil-in-water emulsion composition, wherein component (E) is glycerin monostearyl ether.

The present invention also provides an oil-in-water emulsified composition containing component (F) a phospholipid.

The present invention provides an emulsified composition containing a tocopheryl phosphate and/or a salt thereof, which has good storage stability, provides a deep richness during application, smooth finger sliding, and a firm skin feel after application. It is an excellent oil-in-water emulsion composition.

The tocopheryl phosphate and/or its salt used in the present invention as component (A) is not particularly limited, but is preferably a monoester. is salt. Sodium salts are more preferred. As a commercially available product, TPNa (manufactured by Showa Denko KK) can be exemplified.

The content of component (A) used in the present invention is not particularly limited, but is preferably 0.05 to 3% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The acylmethyltaurate of component (B) used in the present invention is an anionic surfactant, preferably an acylmethyltaurate having an acyl group of 14 to 22 carbon atoms. Examples thereof include stearoylmethyltaurate, palmitoylmethyltaurate, myristoylmethyltaurate, lauroylmethyltaurate, etc. Among them, stearoylmethyltaurate is more preferable. Examples of the salt include alkali metal salts and alkaline earth metal salts, with sodium salts being particularly preferred. NIKKOL SMT (manufactured by Nikko Chemicals Co., Ltd.) can be exemplified as a commercially available product.

The content of component (B) used in the present invention is not particularly limited, but is preferably 0.01 to 2% by weight, more preferably 0.05 to 1% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The higher alcohol having 12 to 22 carbon atoms of the component (C) used in the present invention is not particularly limited, but examples include lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, and arachyl alcohol , behenyl alcohol, etc., and can be used alone or in combination of two or more. Among them, it is preferable to use a mixture of two or more selected from behenyl alcohol, cetyl alcohol and stearyl alcohol, and it is more preferable to use a mixture of behenyl alcohol, cetyl alcohol and stearyl alcohol.

The content of component (C) used in the present invention is not particularly limited, but is preferably 0.5 to 5% by weight, more preferably 1 to 3% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The higher fatty acid having 12 to 22 carbon atoms of component (D) used in the present invention is not particularly limited, but examples include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, linoleic acid, and linolenic acid. acid, arachidonic acid, isostearic acid, etc., and can be used singly or in combination of two or more. Among them, stearic acid and behenic acid are preferred, and behenic acid is more preferred.

The content of component (D) used in the present invention is not particularly limited, but is preferably 0.5 to 5% by weight, more preferably 1 to 3% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The component (E) glycerin monoalkyl ether used in the present invention has a structure in which an alkyl chain having 16 to 18 carbon atoms and glycerin are linked via an ether bond. For example, glycerin monocetyl ether (chimyl alcohol), glycerin monostearyl ether (bacyl alcohol), glycerin monooleyl ether (selachyl alcohol), etc., can be used alone or in combination of two or more. . Among them, glycerin monostearyl ether is preferable, and Bacyl Alcohol EX (manufactured by Nikko Chemicals Co., Ltd.) can be exemplified as a commercially available product.

The content of component (E) used in the present invention is not particularly limited, but is preferably 0.5 to 5% by weight, more preferably 1 to 3% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The phospholipid of component (F) used in the present invention has one or more hydrophobic groups consisting of a phosphate group and an acyl group and/or an alkyl group in the molecule. Examples thereof include phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylglycerol, phosphatidic acid, hydrogenated products thereof, enzyme-modified products, and the like. Any of these can be used as long as they are derived from soybeans, egg yolks, etc., as long as they are commonly used in cosmetics, but hydrogenated soybean phospholipids are preferred. As a commercially available product, Cortsome NC-21 (manufactured by NOF Corporation) can be exemplified.

The content of component (F) used in the present invention is not particularly limited, but is preferably 0.01 to 2% by weight, more preferably 0.05 to 1% by weight in the emulsified composition. Within this range, the storage stability is good, and sufficient effects can be obtained in terms of deep richness upon application, smooth finger slippage, and skin firmness after application.

The oil-in-water emulsion composition of the present invention can further contain various components depending on the purpose of use. For example, UV absorbers, preservatives, antioxidants, whitening agents, vitamins, amino acids, hormones, peptides, bioactive plant extracts, fluorescent materials, pigments, dyes, fragrances, scrubbing agents, binders, extenders, thickeners. , saccharides, nutrients, chelating agents, bactericides, keratin improving agents, keratolytic agents, antibiotics, skin permeation promoters, blood circulation promoters, anti-inflammatory agents, cell activators, anti-inflammatory agents, analgesics, emollients, Emollients, wound healing agents, metabolism promoting agents and the like can be contained within a range that does not impair the effects of the present invention.

The oil-in-water emulsion composition of the present invention can be applied to serums, milky lotions, creams, packs, and the like. The form of the oil-in-water emulsified composition of the present invention may be emulsion, cream, solid, or the like.

EXAMPLES The present invention will be described in more detail below with reference to examples. The invention is not limited by these examples. Incidentally, the content is shown in weight %.

Oil-in-water emulsion compositions having compositions listed in Tables 1 to 5 below were prepared, and storage stability and feeling during use were evaluated.

(Storage stability evaluation method)
The emulsion was stored in a constant temperature bath at 40° C. for 6 months, and the emulsified particles after 3 months and 6 months were evaluated under a microscope and judged according to the following criteria.
(double-circle): It is favorable without a change for 6 months.
◯: Good after 3 months with no change, but emulsified particles are slightly larger after 6 months.
Δ: Emulsified particles are slightly larger after 3 months.
x: Emulsified particles are obviously large after 3 months.

(Usability evaluation method)
A use test was conducted by a female panel (20 persons). Using the obtained oil-in-water emulsified composition, "heavy richness" at the time of application, "smooth finger sliding" and "skin firmness" after application were evaluated according to the following criteria.
(1) Heavy richness ⊚: 18 or more panelists judged that heavy body was felt.
◯: 14 to 17 panelists judged that they felt a heavy richness.
Δ: 9 to 13 panelists judged that they felt a heavy richness.
x: Eight or less people judged that they felt heavy body.
(2) Smooth finger sliding ⊚: 18 or more people judged that they felt smooth finger sliding.
◯: 14 to 17 persons judged that they felt a smooth finger sliding.
Δ: 9 to 13 persons judged that they felt a smooth finger sliding.
x: Eight or less people judged that they felt smooth finger sliding.
(3) Firmness of skin ⊚: 18 or more panelists judged that they felt firmness of skin.
◯: 14 to 17 panelists judged that the skin felt firm.
Δ: 9 to 13 panelists judged that the skin felt firm.
x: Eight or less people judged that the skin felt firm.

(Production method)
After uniformly dispersing or dissolving parts a and b at 80° C., parts a and b were mixed and emulsified using a homomixer. This was cooled to 30°C to obtain an oil-in-water emulsion composition.

From the results in Table 1, in Examples 1 to 7, which are compositions of the present invention, satisfactory results were obtained in all evaluated items. In particular, a composition in which the content of component (A) sodium tocopheryl phosphate is 0.05 to 3% by weight and sodium stearoylmethyltaurate is used as component (B) and the content is 0.05 to 1% by weight. In (Examples 1, 2, 4, and 5), remarkably excellent results were obtained in all evaluated items. On the other hand, the composition containing no component (B) (Comparative Example 1) and the compositions containing sodium stearoyl lactylate and sodium lauroylmethylalanine instead of component (B) (Comparative Examples 2 and 3) are satisfactory. No results were obtained.

From the results in Table 2, the compositions of Examples 8 to 15 of the present invention gave satisfactory results in all evaluated items. In particular, the compositions (Examples 9 and 10) using behenyl alcohol, stearyl alcohol, and cetyl alcohol as the component (C) with a content of 1 to 3% by weight exhibited remarkably excellent results in all evaluated items. was gotten. On the other hand, the composition not containing component (C) (Comparative Example 4) did not yield satisfactory results.

From the results in Table 3, the compositions of Examples 16 to 20 of the present invention gave satisfactory results in all evaluated items. In particular, the compositions (Examples 17 and 18) in which behenic acid was used as the component (D) and contained 1 to 3% by weight of the component (D) gave remarkably excellent results in all evaluated items. On the other hand, the composition not containing component (D) (Comparative Example 5) did not yield satisfactory results.

From the results in Table 4, the compositions of Examples 21 to 25 of the present invention yielded satisfactory results in all evaluated items. In particular, the compositions (Examples 22 and 23) using glycerin monostearyl ether as the component (E) and having a content of 1 to 3% by weight gave remarkably excellent results in all evaluated items. rice field. On the other hand, the composition not containing component (E) (Comparative Example 6) did not yield satisfactory results.

From the results in Table 5, the compositions of Examples 26 to 30 of the present invention gave satisfactory results in all evaluated items. In particular, the composition (Examples 28 and 29) in which the content of the component (F) hydrogenated soybean phospholipid was 0.05 to 1% by weight gave remarkably excellent results in all evaluated items. .

Other examples of the present invention are shown below.

(Example 31)
(Component) (% by weight)
1. Sodium tocopheryl phosphate 1.0
2. Stearoyl methyl taurate sodium 0.4
3. Diglycerin 2.0
4. Phenoxyethanol 0.5
5.1,3-butylene glycol 12.0
6. Sodium hyaluronate 0.1
7. Xanthan gum 0.2
8. Potassium hydroxide 0.1
9. Purified water Balance 10. behenyl alcohol 0.5
11. Stearyl alcohol 0.7
12. Cetyl alcohol 0.3
13. Behenic acid 1.5
14. Stearic acid 0.5
15. Glycerin monostearyl ether 2.0
16. Dextrin palmitate 1.5
17. Beeswax 1.0
18. Vaseline 5.0
19. Diisostearyl malate 5.0
20. Squalane 10.0
21. Isotridecyl isononanoate 5.0
22. Hydrogenated soybean phospholipid 0.2
23. Perfume 0.1
24. Succinoyl atelocollagen liquid*12 5.0
25. Water-soluble collagen solution *13 5.0
(Production method)
Components 1 to 9 were uniformly dispersed at 80°C and added to components 10 to 22 dissolved at 80°C. After that, it was emulsified using a homomixer. After cooling with stirring, component 23 was added at 70°C, components 24 and 25 were added at 50°C, and cooling was stopped at 30°C to obtain an oil-in-water emulsion composition.

Also in Example 31, excellent storage stability was obtained, and satisfactory results were obtained in all evaluation items for feeling during use.

*1: TPNa: manufactured by Showa Denko *2: NIKKOL SMT: manufactured by Nikko Chemicals *3: NIKKOL LMT: manufactured by Nikko Chemicals *4: Hynol 22SS: manufactured by KOKYU ALCOHOL KOGYO *5: Stearyl alcohol NX: KOKYU ALCOHOL KOGYO *6: Cetyl alcohol NX: Kokyu Alcohol Kogyo Co., Ltd. *7: NAA-222: NOF *8: Bacyl alcohol EX: Nikko Chemicals *9: Cortosome NC-21: NOF * 10: NAA-1865: manufactured by NOF Corporation * 11: Chimyl alcohol 100: manufactured by Nikko Chemicals * 12: Cagem Collagen AS: manufactured by Katakura Chikkarin * 13: Alfomaline-CL: manufactured by Technoble

According to the present invention, an emulsified composition containing a tocopheryl phosphate and/or a salt thereof has good storage stability, and has a rich body when applied, smooth finger sliding, and skin firmness after application. It is possible to provide an oil-in-water emulsified composition with excellent feeling.

Claims (4)

The following components (A)-(E):
(A) Tocopheryl phosphate and/or salt thereof (B) Acylmethyl taurine salt (C) Higher alcohol having 12 to 22 carbon atoms (D) Higher fatty acid having 12 to 22 carbon atoms (E) Glycerol monoalkyl An oil-in-water emulsion composition characterized by containing an ether. 2. The oil-in-water emulsion composition according to claim 1, wherein component (B) is sodium stearoylmethyltaurate. 3. The oil-in-water emulsion composition according to claim 1, wherein component (E) is glycerin monostearyl ether. 4. The oil-in-water emulsion composition according to any one of claims 1 to 3, characterized in that it contains component (F) a phospholipid.