JP2022544604A5 - - Google Patents
Info
- Publication number
- JP2022544604A5 JP2022544604A5 JP2022509680A JP2022509680A JP2022544604A5 JP 2022544604 A5 JP2022544604 A5 JP 2022544604A5 JP 2022509680 A JP2022509680 A JP 2022509680A JP 2022509680 A JP2022509680 A JP 2022509680A JP 2022544604 A5 JP2022544604 A5 JP 2022544604A5
- Authority
- JP
- Japan
- Prior art keywords
- trained
- pathway
- model
- dysregulation
- disruption
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025117506A JP2025143491A (ja) | 2019-08-16 | 2025-07-11 | がん検体において細胞経路調節不全を検出するためのシステム及び方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962888163P | 2019-08-16 | 2019-08-16 | |
| US62/888,163 | 2019-08-16 | ||
| US201962904300P | 2019-09-23 | 2019-09-23 | |
| US62/904,300 | 2019-09-23 | ||
| US202062986201P | 2020-03-06 | 2020-03-06 | |
| US62/986,201 | 2020-03-06 | ||
| PCT/US2020/046513 WO2021034712A1 (en) | 2019-08-16 | 2020-08-14 | Systems and methods for detecting cellular pathway dysregulation in cancer specimens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025117506A Division JP2025143491A (ja) | 2019-08-16 | 2025-07-11 | がん検体において細胞経路調節不全を検出するためのシステム及び方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022544604A JP2022544604A (ja) | 2022-10-19 |
| JP2022544604A5 true JP2022544604A5 (https=) | 2023-08-18 |
Family
ID=74646007
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022509680A Pending JP2022544604A (ja) | 2019-08-16 | 2020-08-14 | がん検体において細胞経路調節不全を検出するためのシステム及び方法 |
| JP2024568982A Pending JP2025517450A (ja) | 2019-08-16 | 2023-02-28 | 癌検体における細胞経路調節不全を検出するためのシステム及び方法 |
| JP2025117506A Pending JP2025143491A (ja) | 2019-08-16 | 2025-07-11 | がん検体において細胞経路調節不全を検出するためのシステム及び方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024568982A Pending JP2025517450A (ja) | 2019-08-16 | 2023-02-28 | 癌検体における細胞経路調節不全を検出するためのシステム及び方法 |
| JP2025117506A Pending JP2025143491A (ja) | 2019-08-16 | 2025-07-11 | がん検体において細胞経路調節不全を検出するためのシステム及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11367508B2 (https=) |
| EP (2) | EP4013866A4 (https=) |
| JP (3) | JP2022544604A (https=) |
| AU (1) | AU2020334901A1 (https=) |
| CA (1) | CA3148023A1 (https=) |
| WO (2) | WO2021034712A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020334901A1 (en) * | 2019-08-16 | 2022-03-24 | Tempus Ai, Inc. | Systems and methods for detecting cellular pathway dysregulation in cancer specimens |
| US11645555B2 (en) | 2019-10-12 | 2023-05-09 | International Business Machines Corporation | Feature selection using Sobolev Independence Criterion |
| US11373760B2 (en) * | 2019-10-12 | 2022-06-28 | International Business Machines Corporation | False detection rate control with null-hypothesis |
| CA3174332A1 (en) | 2020-04-21 | 2021-10-28 | Jason PERERA | Tcr/bcr profiling |
| WO2021231713A2 (en) | 2020-05-14 | 2021-11-18 | Ampel Biosolutions, Llc | Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus |
| EP4271837A4 (en) | 2020-12-31 | 2025-10-15 | Tempus Ai Inc | SYSTEMS AND METHODS FOR DETECTING MULTIMOLECULAR BIOMARKERS |
| EP4275208A1 (en) | 2021-01-07 | 2023-11-15 | Tempus Labs, Inc. | Systems and methods for joint low-coverage whole genome sequencing and whole exome sequencing inference of copy number variation for clinical diagnostics |
| US11481235B2 (en) * | 2021-01-11 | 2022-10-25 | Evicore Healthcare MSI, LLC | Database framework model transformation for pathway identification |
| WO2022159774A2 (en) | 2021-01-21 | 2022-07-28 | Tempus Labs, Inc. | METHODS AND SYSTEMS FOR mRNA BOUNDARY ANALYSIS IN NEXT GENERATION SEQUENCING |
| US12412100B2 (en) * | 2021-01-22 | 2025-09-09 | International Business Machines Corporation | Cell state transition features from single cell data |
| US12361542B2 (en) | 2021-03-03 | 2025-07-15 | Tempus Ai, Inc. | Systems and methods for deep orthogonal fusion for multimodal prognostic biomarker discovery |
| CN113421613B (zh) * | 2021-06-08 | 2024-06-18 | 吴安华 | 一种基于铁死亡水平评价胶质母细胞瘤患者免疫治疗反应性的系统及分析方法 |
| WO2023064309A1 (en) | 2021-10-11 | 2023-04-20 | Tempus Labs, Inc. | Methods and systems for detecting alternative splicing in sequencing data |
| EP4430615A4 (en) * | 2021-11-10 | 2026-01-21 | Albert Einstein College Medicine | METHOD FOR MEASURING SOMATIC DNA MUTATION AND DNA DAMAGE PROFILES AND APPROPRIATE DIAGNOSTIC KIT |
| WO2023091316A1 (en) | 2021-11-19 | 2023-05-25 | Tempus Labs, Inc. | Methods and systems for accurate genotyping of repeat polymorphisms |
| WO2023100181A1 (en) * | 2021-12-01 | 2023-06-08 | Hadasit Medical Research Services And Development Ltd. | Machine learning prediction of genetic mutations impact |
| JP2023091970A (ja) * | 2021-12-21 | 2023-07-03 | 行正 塩津 | 提示装置及びプログラム |
| EP4239647A1 (en) | 2022-03-03 | 2023-09-06 | Tempus Labs, Inc. | Systems and methods for deep orthogonal fusion for multimodal prognostic biomarker discovery |
| WO2023168049A2 (en) * | 2022-03-04 | 2023-09-07 | Bostongene Corporation | Cytokine gene expression signatures |
| CN115273966B (zh) * | 2022-08-29 | 2023-03-31 | 西安交通大学 | 谱系树中可变剪接模式和染色质状态动态变化的分析方法 |
| US20240393932A1 (en) * | 2023-02-16 | 2024-11-28 | XAI.health, Inc. | Visualization methods and systems for evaluating performance of a classifier and selection of optimal working thresholds |
| EP4689172A1 (en) * | 2023-03-24 | 2026-02-11 | Foundation Medicine, Inc. | Systems and methods for identifying hla variants |
| US20240355485A1 (en) | 2023-04-13 | 2024-10-24 | Tempus Ai, Inc. | Systems and methods for predicting clinical response |
| WO2024263404A1 (en) * | 2023-06-22 | 2024-12-26 | 23Andme, Inc. | Analyzing and merging data from genome-wide association studies |
| US20250111910A1 (en) | 2023-09-29 | 2025-04-03 | Tempus Al, Inc. | Methods and systems for disease phenotyping using multimodal ehr data and weak supervision |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090299646A1 (en) * | 2004-07-30 | 2009-12-03 | Soheil Shams | System and method for biological pathway perturbation analysis |
| EP2419540B1 (en) * | 2009-04-18 | 2017-05-17 | Merck Sharp & Dohme Corp. | Methods and gene expression signature for assessing ras pathway activity |
| WO2015077725A1 (en) | 2013-11-22 | 2015-05-28 | Dignity Health | Diagnosing idh1 related subgroups and treatment of cancer |
| EP2549399A1 (en) * | 2011-07-19 | 2013-01-23 | Koninklijke Philips Electronics N.V. | Assessment of Wnt pathway activity using probabilistic modeling of target gene expression |
| HK1205767A1 (en) * | 2012-07-26 | 2015-12-24 | The Regents Of The University Of California | Screening, diagnosis and prognosis of autism and other developmental disorders |
| WO2014116881A1 (en) * | 2013-01-23 | 2014-07-31 | Reproductive Genetics And Technology Solutions, Llc | Compositions and methods for genetic analysis of embryos |
| US20170335396A1 (en) * | 2014-11-05 | 2017-11-23 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| KR101785795B1 (ko) | 2015-10-30 | 2017-10-13 | 가톨릭대학교 산학협력단 | 두경부암 예후 예측용 바이오마커 마이크로 rna |
| GB202209539D0 (en) | 2017-06-13 | 2022-08-10 | Bostongene Corp | Systems and methods for identifying cancer treatments from normalized biomarker scores |
| DE102017216112A1 (de) | 2017-09-12 | 2019-03-14 | Thyssenkrupp Ag | Aussetz-System und Aussetz-Verfahren mit zusammenziehbarem Vorleinenausleger |
| FR3072170B1 (fr) | 2017-10-05 | 2020-10-16 | Spade | Dispositif de surveillance pour la detection, en continu, de defauts dans une section de canalisation et systeme de surveillance equipe d’au moins deux dispositifs de surveillance |
| AU2019317440B2 (en) | 2018-08-06 | 2026-01-22 | Tempus Ai, Inc. | A multi-modal approach to predicting immune infiltration based on integrated RNA expression and imaging features |
| AU2019346427A1 (en) | 2018-09-24 | 2021-05-13 | Tempus Ai, Inc. | Methods of normalizing and correcting RNA expression data |
| WO2020081607A1 (en) | 2018-10-15 | 2020-04-23 | Tempus Labs, Inc. | Microsatellite instability determination system and related methods |
| CA3119749A1 (en) * | 2018-11-15 | 2020-05-22 | Ampel Biosolutions, Llc | Machine learning disease prediction and treatment prioritization |
| WO2020142563A1 (en) | 2018-12-31 | 2020-07-09 | Tempus Labs, Inc. | Transcriptome deconvolution of metastatic tissue samples |
| WO2020210487A1 (en) * | 2019-04-12 | 2020-10-15 | Cipher Genetics Inc. | Systems and methods for nutrigenomics and nutrigenetic analysis |
| AU2020334901A1 (en) * | 2019-08-16 | 2022-03-24 | Tempus Ai, Inc. | Systems and methods for detecting cellular pathway dysregulation in cancer specimens |
-
2020
- 2020-08-14 AU AU2020334901A patent/AU2020334901A1/en active Pending
- 2020-08-14 CA CA3148023A patent/CA3148023A1/en active Pending
- 2020-08-14 EP EP20855340.4A patent/EP4013866A4/en active Pending
- 2020-08-14 JP JP2022509680A patent/JP2022544604A/ja active Pending
- 2020-08-14 WO PCT/US2020/046513 patent/WO2021034712A1/en not_active Ceased
- 2020-08-14 US US16/994,315 patent/US11367508B2/en active Active
-
2022
- 2022-05-20 US US17/750,055 patent/US20220351805A1/en active Pending
-
2023
- 2023-02-28 EP EP23808039.4A patent/EP4526885A1/en active Pending
- 2023-02-28 JP JP2024568982A patent/JP2025517450A/ja active Pending
- 2023-02-28 WO PCT/US2023/014196 patent/WO2023224709A1/en not_active Ceased
-
2025
- 2025-07-11 JP JP2025117506A patent/JP2025143491A/ja active Pending
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