JP2022543778A - 核酸配列決定のための方法および試薬、ならびに関連する用途 - Google Patents

核酸配列決定のための方法および試薬、ならびに関連する用途 Download PDF

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JP2022543778A
JP2022543778A JP2022506451A JP2022506451A JP2022543778A JP 2022543778 A JP2022543778 A JP 2022543778A JP 2022506451 A JP2022506451 A JP 2022506451A JP 2022506451 A JP2022506451 A JP 2022506451A JP 2022543778 A JP2022543778 A JP 2022543778A
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nucleic acid
strand
stranded
double
adapter
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JP2022543778A5 (enExample
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ソーク，ジェシー・ジェイ
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Twinstrand Biosciences Inc
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Twinstrand Biosciences Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
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  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2022506451A 2019-08-01 2020-08-01 核酸配列決定のための方法および試薬、ならびに関連する用途 Pending JP2022543778A (ja)

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JP2025209408A JP2026035740A (ja) 2019-08-01 2025-11-28 核酸配列決定のための方法および試薬、ならびに関連する用途

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US201962881936P 2019-08-01 2019-08-01
US62/881,936 2019-08-01
PCT/US2020/044673 WO2021022237A1 (en) 2019-08-01 2020-08-01 Methods and reagents for nucleic acid sequencing and associated applications

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JP2022543778A true JP2022543778A (ja) 2022-10-14
JP2022543778A5 JP2022543778A5 (enExample) 2023-08-08

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JP2025209408A Pending JP2026035740A (ja) 2019-08-01 2025-11-28 核酸配列決定のための方法および試薬、ならびに関連する用途

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US (1) US20220220543A1 (enExample)
EP (1) EP4007818A4 (enExample)
JP (2) JP2022543778A (enExample)
CN (1) CN114502742A (enExample)
AU (1) AU2020321991A1 (enExample)
CA (1) CA3146435A1 (enExample)
IL (1) IL290274A (enExample)
WO (1) WO2021022237A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10844428B2 (en) 2015-04-28 2020-11-24 Illumina, Inc. Error suppression in sequenced DNA fragments using redundant reads with unique molecular indices (UMIS)
SG11201906428SA (en) 2017-01-18 2019-08-27 Illumina Inc Methods and systems for generation and error-correction of unique molecular index sets with heterogeneous molecular lengths
AU2018261332B2 (en) 2017-05-01 2024-12-05 Illumina, Inc. Optimal index sequences for multiplex massively parallel sequencing
EP3622089B1 (en) 2017-05-08 2024-07-17 Illumina, Inc. Method for sequencing using universal short adapters for indexing of polynucleotide samples
US11447818B2 (en) 2017-09-15 2022-09-20 Illumina, Inc. Universal short adapters with variable length non-random unique molecular identifiers
WO2021178893A2 (en) 2020-03-06 2021-09-10 Singular Genomics Systems, Inc. Linked paired strand sequencing
CN115109845B (zh) * 2021-03-18 2025-07-25 武汉大学 Rna中次黄嘌呤的高通量测序检测方法
AU2023236924A1 (en) * 2022-03-15 2024-10-24 Illumina, Inc. Paired-end sequencing
US12091715B2 (en) 2022-04-21 2024-09-17 Paragon Genomics, Inc. Methods and compositions for reducing base errors of massive parallel sequencing using triseq sequencing
US11680293B1 (en) * 2022-04-21 2023-06-20 Paragon Genomics, Inc. Methods and compositions for amplifying DNA and generating DNA sequencing results from target-enriched DNA molecules
GB202209189D0 (en) * 2022-06-22 2022-08-10 Broken String Biosciences Ltd Methods and compositions for nucleic acid sequencing
EP4728092A1 (en) * 2023-06-14 2026-04-22 Illumina, Inc. Determination of modified cytosines

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012012037A1 (en) * 2010-07-19 2012-01-26 New England Biolabs, Inc. Oligonucleotide adaptors: compositions and methods of use
WO2012061832A1 (en) * 2010-11-05 2012-05-10 Illumina, Inc. Linking sequence reads using paired code tags
WO2013123442A1 (en) * 2012-02-17 2013-08-22 Fred Hutchinson Cancer Research Center Compositions and methods for accurately identifying mutations
PT2828218T (pt) * 2012-03-20 2020-11-11 Univ Washington Through Its Center For Commercialization Métodos para baixar a taxa de erro da sequenciação paralela massiva de adn utilizando sequenciação duplex de consensus
EP2847353B1 (en) * 2012-05-10 2022-01-19 The General Hospital Corporation Methods for determining a nucleotide sequence
ES2660989T3 (es) * 2013-12-28 2018-03-27 Guardant Health, Inc. Métodos y sistemas para detectar variantes genéticas
US10435685B2 (en) * 2014-08-19 2019-10-08 Pacific Biosciences Of California, Inc. Compositions and methods for enrichment of nucleic acids
US10465241B2 (en) * 2015-06-15 2019-11-05 The Board Of Trustees Of The Leleand Stanford Junior University High resolution STR analysis using next generation sequencing
CA3006792A1 (en) * 2015-12-08 2017-06-15 Twinstrand Biosciences, Inc. Improved adapters, methods, and compositions for duplex sequencing
WO2018023068A1 (en) * 2016-07-29 2018-02-01 New England Biolabs, Inc. Methods and compositions for preventing concatemerization during template- switching
IL269431B2 (en) * 2017-03-23 2025-05-01 Univ Washington Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing
WO2018183942A1 (en) * 2017-03-31 2018-10-04 Grail, Inc. Improved library preparation and use thereof for sequencing-based error correction and/or variant identification

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Publication number Publication date
WO2021022237A1 (en) 2021-02-04
US20220220543A1 (en) 2022-07-14
IL290274A (en) 2022-04-01
CA3146435A1 (en) 2021-02-04
JP2026035740A (ja) 2026-03-04
EP4007818A4 (en) 2023-09-20
EP4007818A1 (en) 2022-06-08
AU2020321991A1 (en) 2022-03-03
CN114502742A (zh) 2022-05-13

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