JP2022540954A - 血管病変の機能的影響 - Google Patents
血管病変の機能的影響 Download PDFInfo
- Publication number
- JP2022540954A JP2022540954A JP2022503575A JP2022503575A JP2022540954A JP 2022540954 A JP2022540954 A JP 2022540954A JP 2022503575 A JP2022503575 A JP 2022503575A JP 2022503575 A JP2022503575 A JP 2022503575A JP 2022540954 A JP2022540954 A JP 2022540954A
- Authority
- JP
- Japan
- Prior art keywords
- ffr
- score
- vessel
- impact
- values
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 231100000216 vascular lesion Toxicity 0.000 title abstract description 4
- 238000000034 method Methods 0.000 claims abstract description 153
- 230000017531 blood circulation Effects 0.000 claims abstract description 32
- 208000019553 vascular disease Diseases 0.000 claims abstract description 14
- 230000002792 vascular Effects 0.000 claims description 70
- 230000003902 lesion Effects 0.000 claims description 55
- 238000012545 processing Methods 0.000 claims description 32
- 238000011282 treatment Methods 0.000 claims description 29
- 210000005166 vasculature Anatomy 0.000 claims description 23
- 210000004351 coronary vessel Anatomy 0.000 claims description 14
- 238000002405 diagnostic procedure Methods 0.000 claims description 12
- 239000002131 composite material Substances 0.000 claims description 10
- 230000007423 decrease Effects 0.000 claims description 9
- 238000013439 planning Methods 0.000 claims description 9
- 239000008280 blood Substances 0.000 claims description 7
- 210000004369 blood Anatomy 0.000 claims description 7
- 238000013500 data storage Methods 0.000 claims description 7
- 238000013507 mapping Methods 0.000 claims description 7
- 230000002829 reductive effect Effects 0.000 claims description 7
- 238000011144 upstream manufacturing Methods 0.000 claims description 7
- 238000002560 therapeutic procedure Methods 0.000 claims description 5
- 238000009792 diffusion process Methods 0.000 claims description 3
- 208000006440 Open Bite Diseases 0.000 claims description 2
- 230000001131 transforming effect Effects 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 description 25
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 25
- 238000004364 calculation method Methods 0.000 description 22
- 238000013146 percutaneous coronary intervention Methods 0.000 description 17
- 238000003860 storage Methods 0.000 description 17
- 230000006870 function Effects 0.000 description 11
- 238000005259 measurement Methods 0.000 description 11
- 238000003384 imaging method Methods 0.000 description 10
- 208000031481 Pathologic Constriction Diseases 0.000 description 8
- 238000004590 computer program Methods 0.000 description 8
- 230000000250 revascularization Effects 0.000 description 8
- 238000002583 angiography Methods 0.000 description 7
- 208000037804 stenosis Diseases 0.000 description 7
- 230000036262 stenosis Effects 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 230000006872 improvement Effects 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 210000004204 blood vessel Anatomy 0.000 description 5
- 230000001186 cumulative effect Effects 0.000 description 5
- 230000000302 ischemic effect Effects 0.000 description 5
- 230000009467 reduction Effects 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- 230000000747 cardiac effect Effects 0.000 description 4
- 208000028867 ischemia Diseases 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000013459 approach Methods 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000000670 limiting effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 230000010412 perfusion Effects 0.000 description 3
- 238000013077 scoring method Methods 0.000 description 3
- 230000002966 stenotic effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000004218 vascular function Effects 0.000 description 3
- 201000000057 Coronary Stenosis Diseases 0.000 description 2
- 206010011089 Coronary artery stenosis Diseases 0.000 description 2
- 206010057469 Vascular stenosis Diseases 0.000 description 2
- 208000029078 coronary artery disease Diseases 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 230000002526 effect on cardiovascular system Effects 0.000 description 2
- 238000005206 flow analysis Methods 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 230000007654 ischemic lesion Effects 0.000 description 2
- 238000010801 machine learning Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000644 propagated effect Effects 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 230000009466 transformation Effects 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 238000012384 transportation and delivery Methods 0.000 description 2
- 200000000007 Arterial disease Diseases 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- 208000016444 Benign adult familial myoclonic epilepsy Diseases 0.000 description 1
- 206010061818 Disease progression Diseases 0.000 description 1
- 206010053648 Vascular occlusion Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000002399 angioplasty Methods 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000001042 autoregulative effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 210000001715 carotid artery Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000002586 coronary angiography Methods 0.000 description 1
- 238000007887 coronary angioplasty Methods 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 208000016427 familial adult myoclonic epilepsy Diseases 0.000 description 1
- 235000019387 fatty acid methyl ester Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- ZGNITFSDLCMLGI-UHFFFAOYSA-N flubendiamide Chemical compound CC1=CC(C(F)(C(F)(F)F)C(F)(F)F)=CC=C1NC(=O)C1=CC=CC(I)=C1C(=O)NC(C)(C)CS(C)(=O)=O ZGNITFSDLCMLGI-UHFFFAOYSA-N 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 238000010191 image analysis Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002608 intravascular ultrasound Methods 0.000 description 1
- 238000012886 linear function Methods 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 238000010606 normalization Methods 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
- 230000024883 vasodilation Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/02028—Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/504—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of blood vessels, e.g. by angiography
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30101—Blood vessel; Artery; Vein; Vascular
- G06T2207/30104—Vascular flow; Blood flow; Perfusion
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Medical Informatics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Hematology (AREA)
- High Energy & Nuclear Physics (AREA)
- Quality & Reliability (AREA)
- Computer Vision & Pattern Recognition (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Optics & Photonics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962875979P | 2019-07-19 | 2019-07-19 | |
| US62/875,979 | 2019-07-19 | ||
| PCT/US2020/042500 WO2021016071A1 (en) | 2019-07-19 | 2020-07-17 | Functional impact of vascular lesions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2022540954A true JP2022540954A (ja) | 2022-09-20 |
Family
ID=74193345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503575A Pending JP2022540954A (ja) | 2019-07-19 | 2020-07-17 | 血管病変の機能的影響 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220273180A1 (de) |
| EP (1) | EP3998939A4 (de) |
| JP (1) | JP2022540954A (de) |
| IL (1) | IL289945A (de) |
| WO (1) | WO2021016071A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220156923A1 (en) * | 2019-03-12 | 2022-05-19 | Intuitive Surgical Operations, Inc. | Systems and methods for connecting segmented structures |
| WO2020201942A1 (en) | 2019-04-01 | 2020-10-08 | Cathworks Ltd. | Methods and apparatus for angiographic image selection |
| US12039685B2 (en) | 2019-09-23 | 2024-07-16 | Cathworks Ltd. | Methods, apparatus, and system for synchronization between a three-dimensional vascular model and an imaging device |
| US12026881B2 (en) * | 2021-01-04 | 2024-07-02 | Shenzhen Keya Medical Technology Corporation | System and method for joint abnormality detection and physiological condition estimation |
| EP4223218A1 (de) * | 2022-02-04 | 2023-08-09 | Koninklijke Philips N.V. | Intravaskuläre bildgebungsdiagnostik |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2943902B1 (de) | 2012-10-24 | 2020-03-11 | CathWorks Ltd. | Automatisiertes messsystem und verfahren zur bewertung einer koronararterienerkrankung |
| US9858387B2 (en) | 2013-01-15 | 2018-01-02 | CathWorks, LTD. | Vascular flow assessment |
| EP3954298A3 (de) * | 2013-10-24 | 2022-03-16 | Cathworks Ltd. | Bestimmung vaskulärer eigenschaften mit korrespondenzmodellierung eines gefässbaums |
| JP6262027B2 (ja) | 2014-03-10 | 2018-01-17 | 東芝メディカルシステムズ株式会社 | 医用画像処理装置 |
| WO2016092420A1 (en) * | 2014-12-08 | 2016-06-16 | Koninklijke Philips N.V. | Devices, systems, and methods for vessel assessment and intervention recommendation |
| JP7036742B2 (ja) | 2016-05-16 | 2022-03-15 | キャスワークス リミテッド | 血管評価システム |
| EP4445835A2 (de) * | 2017-02-24 | 2024-10-16 | HeartFlow, Inc. | Systeme und verfahren zur identifizierung anatomisch relevanter blutflusseigenschaften in einem patienten |
-
2020
- 2020-07-17 JP JP2022503575A patent/JP2022540954A/ja active Pending
- 2020-07-17 WO PCT/US2020/042500 patent/WO2021016071A1/en unknown
- 2020-07-17 EP EP20843503.2A patent/EP3998939A4/de active Pending
- 2020-07-17 US US17/627,594 patent/US20220273180A1/en active Pending
-
2022
- 2022-01-18 IL IL289945A patent/IL289945A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021016071A1 (en) | 2021-01-28 |
| EP3998939A1 (de) | 2022-05-25 |
| EP3998939A4 (de) | 2023-08-09 |
| US20220273180A1 (en) | 2022-09-01 |
| IL289945A (en) | 2022-03-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7048561B2 (ja) | 血管形状及び生理学から血流特性を推定するシステム及び方法 | |
| US11887305B1 (en) | Systems and methods for identifying personalized vascular implants from patient-specific anatomic data | |
| JP2022540954A (ja) | 血管病変の機能的影響 | |
| JP6378779B2 (ja) | 流量比を用いて血流の特徴を決定するシステム及び方法 | |
| JP5944606B2 (ja) | 患者固有の血流のモデリングのための方法およびシステム | |
| Wong et al. | Coronary arteries hemodynamics: effect of arterial geometry on hemodynamic parameters causing atherosclerosis | |
| JP6215469B2 (ja) | 最適化された診断能のための境界条件を用いて血流をモデル化するための方法及びシステム | |
| KR101910233B1 (ko) | 맥관구조를 수치 평가하는 시스템들 및 방법들 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230630 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20240318 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240409 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20240705 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240909 |