JP2022534716A5 - - Google Patents

Info

Publication number
JP2022534716A5
JP2022534716A5 JP2021570189A JP2021570189A JP2022534716A5 JP 2022534716 A5 JP2022534716 A5 JP 2022534716A5 JP 2021570189 A JP2021570189 A JP 2021570189A JP 2021570189 A JP2021570189 A JP 2021570189A JP 2022534716 A5 JP2022534716 A5 JP 2022534716A5
Authority
JP
Japan
Prior art keywords
cancer
cells
seq
vector
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021570189A
Other languages
English (en)
Japanese (ja)
Other versions
JP7621979B2 (ja
JP2022534716A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/034639 external-priority patent/WO2020243134A1/en
Publication of JP2022534716A publication Critical patent/JP2022534716A/ja
Publication of JP2022534716A5 publication Critical patent/JP2022534716A5/ja
Priority to JP2025005148A priority Critical patent/JP2025063184A/ja
Application granted granted Critical
Publication of JP7621979B2 publication Critical patent/JP7621979B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021570189A 2019-05-27 2020-05-27 ウイルスベクターおよびその養子細胞療法における使用 Active JP7621979B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025005148A JP2025063184A (ja) 2019-05-27 2025-01-15 ウイルスベクターおよびその養子細胞療法における使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962853123P 2019-05-27 2019-05-27
US62/853,123 2019-05-27
PCT/US2020/034639 WO2020243134A1 (en) 2019-05-27 2020-05-27 Viral vectors and their use in adoptive cellular therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025005148A Division JP2025063184A (ja) 2019-05-27 2025-01-15 ウイルスベクターおよびその養子細胞療法における使用

Publications (3)

Publication Number Publication Date
JP2022534716A JP2022534716A (ja) 2022-08-03
JP2022534716A5 true JP2022534716A5 (https=) 2023-06-02
JP7621979B2 JP7621979B2 (ja) 2025-01-27

Family

ID=71094837

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021570189A Active JP7621979B2 (ja) 2019-05-27 2020-05-27 ウイルスベクターおよびその養子細胞療法における使用
JP2025005148A Pending JP2025063184A (ja) 2019-05-27 2025-01-15 ウイルスベクターおよびその養子細胞療法における使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025005148A Pending JP2025063184A (ja) 2019-05-27 2025-01-15 ウイルスベクターおよびその養子細胞療法における使用

Country Status (20)

Country Link
US (2) US11975025B2 (https=)
EP (1) EP3976805A1 (https=)
JP (2) JP7621979B2 (https=)
KR (1) KR20220029584A (https=)
CN (1) CN113874516A (https=)
AU (1) AU2020283500B2 (https=)
BR (1) BR112021023782A2 (https=)
CA (1) CA3141505A1 (https=)
CL (1) CL2021003146A1 (https=)
CO (1) CO2021017650A2 (https=)
CR (1) CR20210669A (https=)
EA (1) EA202193139A1 (https=)
IL (1) IL288403A (https=)
MA (1) MA56036A (https=)
MX (1) MX2021014552A (https=)
PE (1) PE20220164A1 (https=)
PH (1) PH12021552979A1 (https=)
SG (1) SG11202112860PA (https=)
TW (2) TW202536185A (https=)
WO (1) WO2020243134A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201520539D0 (en) * 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
KR20240007775A (ko) 2016-12-08 2024-01-16 이매틱스 바이오테크놀로지스 게엠베하 T 세포 수용체 및 이를 사용하는 면역 요법
SG11202111865UA (en) * 2019-05-01 2021-11-29 Pact Pharma Inc Compositions and methods for the treatment of cancer using a tet2 engineered t cell therapy
PH12021553152A1 (en) * 2019-06-18 2022-08-15 Regeneron Pharma Mage-a4 t cell receptors and methods of use thereof
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
TW202241938A (zh) * 2020-12-31 2022-11-01 美商英麥提克斯股份有限公司 Cd8多肽、組合物及其使用方法
WO2022233956A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
US20230190806A1 (en) * 2021-10-06 2023-06-22 Immatics Biotechnologies Gmbh Methods of treating metastatic lesions and compositions thereof
EP4448108A1 (en) * 2021-11-08 2024-10-23 Immatics Biotechnologies GmbH Adoptive cell therapy combination treatment and compositions thereof
EP4472742A1 (en) * 2022-02-03 2024-12-11 University College Cardiff Consultants Limited Novel t-cell receptor
US20230348561A1 (en) * 2022-04-28 2023-11-02 Immatics US, Inc. Dominant negative tgfbeta receptor polypeptides, cd8 polypeptides, cells, compositions, and methods of using thereof
EP4501954A1 (en) * 2023-08-02 2025-02-05 Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Gemeinschaft A nucleic acid encoding a cd8 alpha beta co-receptor, cells and pharmaceutical compositions comprising the same
CN117777314B (zh) * 2024-02-26 2024-05-14 赛德特生物制药有限公司 慢病毒载体及其应用
WO2026008886A1 (en) 2024-07-05 2026-01-08 Immatics Biotechnologies Gmbh Means and methods for the quantification of target expression
WO2026033136A1 (en) 2024-08-09 2026-02-12 Immatics Biotechnologies Gmbh Advanced treatment modalities for anti-prame tcr-engineered immune cells

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (https=) 1974-06-07 1981-03-18
US4231938A (en) 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4444784A (en) 1980-08-05 1984-04-24 Merck & Co., Inc. Antihypercholesterolemic compounds
DK149080C (da) 1980-06-06 1986-07-28 Sankyo Co Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
US4450171A (en) 1980-08-05 1984-05-22 Merck & Co., Inc. Antihypercholesterolemic compounds
US4448784A (en) 1982-04-12 1984-05-15 Hoechst-Roussel Pharmaceuticals, Inc. 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof
US4739073A (en) 1983-11-04 1988-04-19 Sandoz Pharmaceuticals Corp. Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
US4681893A (en) 1986-05-30 1987-07-21 Warner-Lambert Company Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
US4915954A (en) 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering a drug at two different rates
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
US5316765A (en) 1989-09-07 1994-05-31 Karl Folkers Foundation For Biomedical And Clinical Research Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies
EP0633943A4 (en) 1992-04-03 1997-05-02 Alexander T Young GENTHERAPY USING TARGETED VIRAL VECTORS.
DE4309553A1 (de) 1993-03-24 1994-09-29 Bayer Ag Verfahren zur Herstellung von 3R,5S-(+)-Natrium-erythro-(E)-7-(4-(4-flurophenyl)-2,6-diisopropyl-5-methoxymethyl-pyrid-3-yl)-3,5-dihydroxy-hept-6-enoat
AU682253B2 (en) 1994-01-28 1997-09-25 Immunex Corporation CD 69 transcriptional regulatory elements
US5849589A (en) 1996-03-11 1998-12-15 Duke University Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
GB0028429D0 (en) 2000-11-22 2001-01-10 Astrazeneca Ab Therapy
GB0114533D0 (en) 2001-06-14 2001-08-08 Avidex Ltd Substances
GB0218781D0 (en) 2002-08-13 2002-09-18 Astrazeneca Ab Chemical process
US20050042217A1 (en) 2003-03-19 2005-02-24 Yan Qi Specific inhibition of allorejection
WO2010042490A1 (en) * 2008-10-06 2010-04-15 Boston Medical Center Corporation A single lentiviral vector system for induced pluripotent (ips) stem cells derivation
US20120064100A1 (en) 2009-03-18 2012-03-15 Simon Barry Biomarkers and uses thereof
US9840695B2 (en) 2009-04-28 2017-12-12 Agriculture Victoria Services Pty Ltd Plant technology
GB201004551D0 (en) 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer
ES2602743T3 (es) 2010-09-08 2017-02-22 Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Receptores de antígenos quiméricos con una región bisagra optimizada
EP2931893A1 (en) 2012-12-13 2015-10-21 Universität Leipzig T-cell modulation by exon skipping
EP4166148B1 (en) 2014-06-06 2026-02-18 Memorial Sloan-Kettering Cancer Center Mesothelin-targeted chimeric antigen receptors and uses thereof
US10975137B2 (en) 2014-11-06 2021-04-13 University Of Maryland, Baltimore CD8a and t cell receptor variants and methods of using same in modulating immune cell responses
GB201423361D0 (en) 2014-12-30 2015-02-11 Immatics Biotechnologies Gmbh Method for the absolute Quantification of naturally processed HLA-Restricted cancer peptides
GB201504502D0 (en) 2015-03-17 2015-04-29 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
GB201505585D0 (en) 2015-03-31 2015-05-13 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers
GB201507719D0 (en) 2015-05-06 2015-06-17 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides and scaffolds thereof for use in immunotherapy against colorectal carcinoma (CRC) and other cancers
GB201510771D0 (en) 2015-06-19 2015-08-05 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy and methods for generating scaffolds for the use against pancreatic cancer
GB201511191D0 (en) 2015-06-25 2015-08-12 Immatics Biotechnologies Gmbh T-cell epitopes for the immunotherapy of myeloma
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
GB201511792D0 (en) 2015-07-06 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers
MY189596A (en) 2015-07-15 2022-02-18 Immatics Biotechnologies Gmbh A novel peptides for use in immunotherapy against epithelial ovarian cancer and other cancers
GB201513921D0 (en) 2015-08-05 2015-09-23 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers
US10335471B2 (en) 2015-08-28 2019-07-02 Immatics Biotechnologies Gmbh Method for treating cancer with activated T cells
CN108513576A (zh) 2015-09-14 2018-09-07 高山免疫科学股份有限公司 可调变体免疫球蛋白超家族结构域和工程改造的细胞治疗
GB201517538D0 (en) 2015-10-05 2015-11-18 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
HK1258444A1 (zh) 2015-10-09 2019-11-15 Immatics Biotechnologies Gmbh 抗wt1/hla特异性抗体
JP7123794B2 (ja) 2015-12-09 2022-08-23 メモリアル スローン ケタリング キャンサー センター 免疫細胞組成物及びそれを使用する方法
GB201521746D0 (en) 2015-12-10 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against CLL and other cancers
GB201521894D0 (en) 2015-12-11 2016-01-27 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against various cancers
GB201522667D0 (en) 2015-12-22 2016-02-03 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against breast cancer and other cancers
CN116769054A (zh) 2016-02-05 2023-09-19 奥里尼斯生物科学私人有限公司 双特异性信号传导剂及其用途
GB201602918D0 (en) 2016-02-19 2016-04-06 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against NHL and other cancers
GB201603568D0 (en) 2016-03-01 2016-04-13 Immatics Biotechnologies Gmbh Efficient treatment options including peptides and combination of peptide and cell based medicaments for use in immunotherapy against urinary bladder cancer
GB201603987D0 (en) 2016-03-08 2016-04-20 Immatics Biotechnologies Gmbh Uterine cancer treatments
GB201604492D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
GB201604458D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides and combination of peptides for use in immunotherapy against cancers
GB201604494D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Transfected T-Cells and T-Cell receptors for use in immunotherapy against cancers
CN116731156A (zh) 2016-03-16 2023-09-12 伊玛提克斯生物技术有限公司 用于癌症免疫治疗的转染t细胞和t细胞受体
US11446398B2 (en) 2016-04-11 2022-09-20 Obsidian Therapeutics, Inc. Regulated biocircuit systems
CA3032838A1 (en) 2016-08-04 2018-02-08 Memorial Sloan-Kettering Cancer Center Compositions and methods for immunotherapy
ZA201900664B (en) 2016-08-17 2021-09-29 Paul Ehrlich Strasse 15 Tuebingen 72076 Germany T cell receptors and immune therapy using the same
DE102016115246C5 (de) 2016-08-17 2018-12-20 Immatics Biotechnologies Gmbh Neue t-zellrezeptoren und deren verwendung in immuntherapie
CN109996868A (zh) * 2016-09-23 2019-07-09 弗雷德哈钦森癌症研究中心 特异性用于次要组织相容性(h)抗原ha-1的tcr及其用途
EP3300863B1 (en) 2016-09-28 2020-06-17 Braun GmbH Electric shaver
DE102016123847B3 (de) 2016-12-08 2018-04-05 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
DE102016123859B3 (de) 2016-12-08 2018-03-01 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
KR20240007775A (ko) 2016-12-08 2024-01-16 이매틱스 바이오테크놀로지스 게엠베하 T 세포 수용체 및 이를 사용하는 면역 요법
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
US20190359678A1 (en) 2017-02-09 2019-11-28 The Regents Of The University Of California Chimeric t cell antigen receptors and methods of use thereof
US11236145B2 (en) 2017-03-23 2022-02-01 Immatics Biotechnologies Gmbh T cell receptors and immune therapy using the same against PRAME positive cancers
DE102017106305A1 (de) * 2017-03-23 2018-09-27 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapien gegen prame-positive Krebsarten
EA201992416A1 (ru) 2017-04-10 2020-02-25 Имматикс Байотекнолоджиз Гмбх Пептиды и комбинации пептидов для применения в иммунотерапии лейкозов и других видов рака
WO2018189148A1 (en) 2017-04-10 2018-10-18 Immatics Biotechnologies Gmbh Peptides and combination thereof for use in the immunotherapy against cancers
US11235004B2 (en) * 2017-06-30 2022-02-01 Innovative Cellular Therapeutics Holdings, Ltd. Lymphocyte cell lines and uses thereof
DE102017114737A1 (de) 2017-06-30 2019-01-03 Immatics Biotechnologies Gmbh Neue T-Zellrezeptoren und deren Verwendung in Immuntherapie
LT3428194T (lt) 2017-07-14 2021-12-10 Immatics Biotechnologies Gmbh Pagerinta dvejopo savitumo polipeptido molekulė
JP2020537515A (ja) 2017-10-03 2020-12-24 ジュノー セラピューティクス インコーポレイテッド Hpv特異的結合分子
US11008556B2 (en) 2017-10-12 2021-05-18 Innovative Cellular Therapeutics Holdings, Ltd. Chimeric antigen receptor (CAR) and T cell receptor (TCR) modified T cells
KR20250052472A (ko) 2017-11-06 2025-04-18 이매틱스 바이오테크놀로지스 게엠베하 신규 조작된 t 세포 수용체 및 이를 사용하는 면역 요법
BR112020016176A2 (pt) 2018-02-09 2022-02-22 Immatics Us Inc Métodos de transdução de uma célula t, célula t transduzida geneticamente, composição farmacêutica, métodos de preparação de uma população de células t e uso da célula t
DE102018107224A1 (de) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
DE102018108612A1 (de) 2018-03-21 2019-09-26 Immatics US, Inc. Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen
CA3097396A1 (en) * 2018-04-19 2019-10-24 Baylor College Of Medicine Reprogramming cd4 t cells into cytotoxic cd8 cells by forced expression of cd8ab and class 1 restricted t cell receptors
WO2020049496A1 (en) 2018-09-05 2020-03-12 Glaxosmithkline Intellectual Property Development Limited T cell modification

Similar Documents

Publication Publication Date Title
JP2022534716A5 (https=)
US20250051418A1 (en) Viral vectors and use thereof in adoptive cellular therapy
JP6419706B2 (ja) ミニプロモーターカセットを含むレトロウイルスベクター
US12123013B2 (en) WPRE mutant constructs, compositions, and methods thereof
JP5873807B2 (ja) B細胞を形質導入するためのベクターおよび方法
JP2015512263A5 (https=)
JP2023517940A5 (https=)
CA2943640A1 (en) A retroviral vector having immune-stimulating activity
Olbrich et al. Reconstructing the immune system with lentiviral vectors
Stärck et al. Immunotherapy with TCR-redirected T cells: comparison of TCR-transduced and TCR-engineered hematopoietic stem cell–derived T cells
Norton et al. Recent advances in lentiviral vaccines for HIV-1 infection
JP2024502034A5 (https=)
TH2101007272A (th) เวกเตอร์ไวรัสและการใช้ของสิ่งดังกล่าวในการรักษาเซลล์แบบอดอฟทีฟ
CA3210543A1 (en) Methods for increasing viral transduction of cells
Brenner et al. Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells
Balar et al. Nonreplicating viral vectors for vaccine delivery
Tenesaca-Cayambe et al. Statins act as transient type I interferon inhibitors to enable the antitumor activity of modified vaccinia Ankara viral vectors
Rosewell Shaw et al. HydrAd: A Helper-Dependent Adenovirus Targeting Multiple Immune Pathways for Cancer Immunotherapy. Cancers 2022, 14, 2769
Stephenson et al. Combining Oncolytic Viruses with Cancer Immunotherapy
Engels Optimisation of retroviral gene transfer in T lymphocytes for the redirection of PBL-specificity