JP2022533976A - バクテリア由来の外膜小胞の供給 - Google Patents

バクテリア由来の外膜小胞の供給 Download PDF

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JP2022533976A
JP2022533976A JP2021568646A JP2021568646A JP2022533976A JP 2022533976 A JP2022533976 A JP 2022533976A JP 2021568646 A JP2021568646 A JP 2021568646A JP 2021568646 A JP2021568646 A JP 2021568646A JP 2022533976 A JP2022533976 A JP 2022533976A
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omvs
pharmaceutical formulation
formulation according
omv
vaccine
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Japanese (ja)
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JPWO2020229846A5 (enExample
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カーディング、サイモン
ステンツ、レギス
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クアドラム インスティテュート バイオサイエンス
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
JP2021568646A 2019-05-15 2020-05-15 バクテリア由来の外膜小胞の供給 Pending JP2022533976A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1906830.3 2019-05-15
GBGB1906830.3A GB201906830D0 (en) 2019-05-15 2019-05-15 Delivery of bacteria-derived outer membrane vesicles
PCT/GB2020/051204 WO2020229846A2 (en) 2019-05-15 2020-05-15 Delivery of Bacteria-Derived Outer Membrane Vesicles

Publications (2)

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JP2022533976A true JP2022533976A (ja) 2022-07-27
JPWO2020229846A5 JPWO2020229846A5 (enExample) 2023-03-30

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JP2021568646A Pending JP2022533976A (ja) 2019-05-15 2020-05-15 バクテリア由来の外膜小胞の供給

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US (1) US20220175901A1 (enExample)
EP (1) EP3969042A2 (enExample)
JP (1) JP2022533976A (enExample)
GB (1) GB201906830D0 (enExample)
WO (1) WO2020229846A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114672507B (zh) * 2022-03-22 2024-04-16 浙江工业大学 一种可递呈多个异源肽或蛋白质的细菌外膜囊泡及其构建方法和应用
CN119875903B (zh) * 2025-01-13 2025-09-19 南昌大学 一种基于细菌外膜囊泡的抗生素载体及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013523838A (ja) * 2010-04-07 2013-06-17 シェン，ユエ 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム
WO2017187190A1 (en) * 2016-04-29 2017-11-02 The Institute Of Food Research Engineering gut commensal bacteria to express heterologous proteins in their outer membrane vesicles (omvs) for delivery to the gi-tract

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201817194D0 (en) * 2018-10-22 2018-12-05 Quadram Inst Bioscience Gut bacteria derived microvesicles for vaccine delivery

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013523838A (ja) * 2010-04-07 2013-06-17 シェン，ユエ 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム
WO2017187190A1 (en) * 2016-04-29 2017-11-02 The Institute Of Food Research Engineering gut commensal bacteria to express heterologous proteins in their outer membrane vesicles (omvs) for delivery to the gi-tract

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CARVALHO, A. L. ET AL.: "Use of bioengineered human commensal gut bacteria-derived microvesicles for mucosal plague vaccine d", CLINICAL AND EXPERIMENTAL IMMUNOLOGY, vol. 196, no. 3, JPN6024012856, 15 April 2019 (2019-04-15), pages 287 - 304, ISSN: 0005519405 *
KIM, O. Y. ET AL.: "Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response", NATURE COMMUNICATIONS, vol. 8, no. 1, JPN6024012854, 20 September 2017 (2017-09-20), pages 626, ISSN: 0005519407 *
LEE, T. Y. ET AL.: "Outer membrane vesicles harboring modified lipid A moiety augment the efficacy of an influenza vacci", VACCINE, vol. 35, no. 4, JPN6024012855, 23 December 2016 (2016-12-23), pages 586 - 595, ISSN: 0005519406 *

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Publication number Publication date
WO2020229846A2 (en) 2020-11-19
WO2020229846A3 (en) 2021-01-14
GB201906830D0 (en) 2019-06-26
EP3969042A2 (en) 2022-03-23
US20220175901A1 (en) 2022-06-09

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