JP2022523514A - 神経認知障害を処置するための組成物及び方法 - Google Patents
神経認知障害を処置するための組成物及び方法 Download PDFInfo
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- JP2022523514A JP2022523514A JP2021544752A JP2021544752A JP2022523514A JP 2022523514 A JP2022523514 A JP 2022523514A JP 2021544752 A JP2021544752 A JP 2021544752A JP 2021544752 A JP2021544752 A JP 2021544752A JP 2022523514 A JP2022523514 A JP 2022523514A
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- A—HUMAN NECESSITIES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- A61K40/00—Cellular immunotherapy
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- A61K40/41—Vertebrate antigens
- A61K40/414—Nervous system antigens
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/00—Drugs for disorders of the nervous system
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
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- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
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- Developmental Biology & Embryology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024231447A JP2025062601A (ja) | 2019-02-01 | 2024-12-27 | 神経認知障害を処置するための組成物及び方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962800177P | 2019-02-01 | 2019-02-01 | |
| US62/800,177 | 2019-02-01 | ||
| PCT/US2020/016206 WO2020160468A1 (en) | 2019-02-01 | 2020-01-31 | Compositions and methods for treating neurocognitive disorders |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024231447A Division JP2025062601A (ja) | 2019-02-01 | 2024-12-27 | 神経認知障害を処置するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022523514A true JP2022523514A (ja) | 2022-04-25 |
| JP2022523514A5 JP2022523514A5 (https=) | 2023-04-27 |
| JPWO2020160468A5 JPWO2020160468A5 (https=) | 2023-04-27 |
Family
ID=71840202
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021544752A Pending JP2022523514A (ja) | 2019-02-01 | 2020-01-31 | 神経認知障害を処置するための組成物及び方法 |
| JP2024231447A Pending JP2025062601A (ja) | 2019-02-01 | 2024-12-27 | 神経認知障害を処置するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024231447A Pending JP2025062601A (ja) | 2019-02-01 | 2024-12-27 | 神経認知障害を処置するための組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220133808A1 (https=) |
| EP (1) | EP3917620A4 (https=) |
| JP (2) | JP2022523514A (https=) |
| CA (1) | CA3127808A1 (https=) |
| IL (1) | IL285270A (https=) |
| MA (1) | MA54880A (https=) |
| WO (1) | WO2020160468A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190248A1 (ar) | 2017-04-21 | 2019-10-20 | Amgen Inc | بروتينات ربط مولد ضد trem2 واستخداماته |
| CN112204050B (zh) | 2018-01-31 | 2025-03-14 | 艾莱克特有限责任公司 | 抗ms4a6a抗体及其使用方法 |
| CN111971301B (zh) | 2018-01-31 | 2025-01-07 | 艾莱克特有限责任公司 | 抗ms4a4a抗体及其使用方法 |
| EP4037696A4 (en) * | 2019-10-01 | 2024-02-07 | Children's Medical Center Corporation | Compositions and methods for treating alzheimer's disease |
| EP4146797A1 (en) * | 2020-05-06 | 2023-03-15 | Orchard Therapeutics (Europe) Limited | Treatment for neurodegenerative diseases |
| US20230322897A1 (en) * | 2020-07-02 | 2023-10-12 | Avrobio, Inc. | Compositions and methods for treating neurocognitive disorders |
| US20230265456A1 (en) * | 2020-08-10 | 2023-08-24 | Fundacion Para La Investigacion Medica Aplicada | Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis |
| US20220127347A1 (en) * | 2020-10-26 | 2022-04-28 | The Regents Of The University Of California | Inhibition of Tau Propagation |
| JP2024516548A (ja) | 2021-04-08 | 2024-04-16 | ジョスリン ダイアビーティス センター インコーポレイテッド | 腎機能低下の診断及び予測の方法 |
| AU2022441199A1 (en) * | 2021-09-27 | 2024-05-16 | Curelab Oncology, Inc. | Prevention and treatment of diseases by modulating activity of mesenchymal stem cells with p62 (sqstm1)-encoding vector and pharmaceutical formulations containing p62 (sqstm1) proteins |
| US20250051391A1 (en) * | 2021-12-15 | 2025-02-13 | The Governing Council Of The University Of Toronto | Peptide inhibitors and methods for inhibiting protein aggregation in neurons and neurodegenerative diseases |
| WO2024178386A1 (en) * | 2023-02-24 | 2024-08-29 | Aarhus Universitet | Methods of treating endosomal trafficking diseases |
| WO2025064926A1 (en) * | 2023-09-22 | 2025-03-27 | The Board Of Regents Of The University Of Texas System | Novel secretory signal peptides and uses thereof |
| CN117736321A (zh) * | 2023-12-20 | 2024-03-22 | 中国人民解放军空军军医大学 | 一种乙酰化修饰的特异性抗体及其应用 |
| WO2025186293A1 (en) * | 2024-03-06 | 2025-09-12 | Institut National de la Santé et de la Recherche Médicale | Chmp2b mutants for use for treating infection |
| KR20260001543A (ko) * | 2024-06-25 | 2026-01-06 | 연세대학교 산학협력단 | 바이러스 벡터를 포함한 난청 치료용 조성물 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017147509A1 (en) * | 2016-02-25 | 2017-08-31 | Marco Colonna | Compositions comprising trem2 and methods of use thereof |
| WO2018195506A1 (en) * | 2017-04-21 | 2018-10-25 | Amgen Inc. | Trem2 antigen binding proteins and uses thereof |
| KR20180130060A (ko) * | 2017-05-26 | 2018-12-06 | 가천대학교 산학협력단 | 알츠하이머병 관련 30개 유전자를 이용한 유전적 진단방법 |
| WO2019021233A1 (en) * | 2017-07-27 | 2019-01-31 | Novartis Ag | TREM2 VARIANTS RESISTANT TO SHEDDASE |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4869399A (en) * | 1998-07-10 | 2000-02-01 | Curagen Corporation | Interaction of human beta amyloid precursor protein (beta-app) with human lon-protease like protein (hslon) |
| US20050163760A1 (en) * | 2001-12-06 | 2005-07-28 | Nathalie Cartier-Lacave | Use of cd34+ hematopoietic progenitor cells for the treatment of cns disorders |
| US20130102538A1 (en) * | 2010-05-05 | 2013-04-25 | Amicus Therapeutics, Inc. | Method of treating alzheimer's disease using pharmacological chaperones to increase presenilin function and gamma-secretase activity |
| JP2016537995A (ja) * | 2013-11-05 | 2016-12-08 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 新しいアルツハイマー病動物モデル |
-
2020
- 2020-01-31 MA MA054880A patent/MA54880A/fr unknown
- 2020-01-31 EP EP20749692.8A patent/EP3917620A4/en active Pending
- 2020-01-31 JP JP2021544752A patent/JP2022523514A/ja active Pending
- 2020-01-31 US US17/427,252 patent/US20220133808A1/en active Pending
- 2020-01-31 CA CA3127808A patent/CA3127808A1/en active Pending
- 2020-01-31 WO PCT/US2020/016206 patent/WO2020160468A1/en not_active Ceased
-
2021
- 2021-08-01 IL IL285270A patent/IL285270A/en unknown
-
2024
- 2024-12-27 JP JP2024231447A patent/JP2025062601A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017147509A1 (en) * | 2016-02-25 | 2017-08-31 | Marco Colonna | Compositions comprising trem2 and methods of use thereof |
| WO2018195506A1 (en) * | 2017-04-21 | 2018-10-25 | Amgen Inc. | Trem2 antigen binding proteins and uses thereof |
| KR20180130060A (ko) * | 2017-05-26 | 2018-12-06 | 가천대학교 산학협력단 | 알츠하이머병 관련 30개 유전자를 이용한 유전적 진단방법 |
| WO2019021233A1 (en) * | 2017-07-27 | 2019-01-31 | Novartis Ag | TREM2 VARIANTS RESISTANT TO SHEDDASE |
Non-Patent Citations (4)
| Title |
|---|
| ALZHEIMER'S & DEMENTIA, vol. 11, JPN6024004284, 2015, pages 1277 - 1285, ISSN: 0005406927 * |
| BIOLOGICAL PSYCHIATRY, vol. 77, JPN6024004286, 2015, pages 43 - 51, ISSN: 0005406929 * |
| BIOLOGICAL PSYCHIATRY, vol. 83, JPN6024004285, 2018, pages 300 - 310, ISSN: 0005406928 * |
| NEUROBIOLOGY OF AGING, vol. 36, JPN6024004283, 2015, pages 545 - 9, ISSN: 0005406926 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020160468A1 (en) | 2020-08-06 |
| MA54880A (fr) | 2021-12-08 |
| CA3127808A1 (en) | 2020-08-06 |
| EP3917620A1 (en) | 2021-12-08 |
| IL285270A (en) | 2021-09-30 |
| JP2025062601A (ja) | 2025-04-14 |
| EP3917620A4 (en) | 2023-02-08 |
| US20220133808A1 (en) | 2022-05-05 |
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