JP2022517531A - 神経学的疾患のための二重幹細胞治療 - Google Patents
神経学的疾患のための二重幹細胞治療 Download PDFInfo
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- JP2022517531A JP2022517531A JP2021537075A JP2021537075A JP2022517531A JP 2022517531 A JP2022517531 A JP 2022517531A JP 2021537075 A JP2021537075 A JP 2021537075A JP 2021537075 A JP2021537075 A JP 2021537075A JP 2022517531 A JP2022517531 A JP 2022517531A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
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- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/599—Cell markers; Cell surface determinants with CD designations not provided for elsewhere
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/80—Neurotransmitters; Neurohormones
- C12N2501/815—Dopamine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/08—Coculture with; Conditioned medium produced by cells of the nervous system
- C12N2502/081—Coculture with; Conditioned medium produced by cells of the nervous system neurons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1171—Haematopoietic stem cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
- C12N2502/137—Blood-borne mesenchymal stem cells, e.g. Msc from umbilical cord blood
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
- C12N2533/32—Polylysine, polyornithine
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- C—CHEMISTRY; METALLURGY
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962794041P | 2019-01-18 | 2019-01-18 | |
| US62/794,041 | 2019-01-18 | ||
| PCT/US2020/014041 WO2020150580A1 (en) | 2019-01-18 | 2020-01-17 | Dual stem cell therapy for neurological conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022517531A true JP2022517531A (ja) | 2022-03-09 |
| JP2022517531A5 JP2022517531A5 (https=) | 2022-10-21 |
Family
ID=71614511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021537075A Pending JP2022517531A (ja) | 2019-01-18 | 2020-01-17 | 神経学的疾患のための二重幹細胞治療 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220072050A1 (https=) |
| EP (1) | EP3911342A4 (https=) |
| JP (1) | JP2022517531A (https=) |
| CA (1) | CA3127090A1 (https=) |
| WO (1) | WO2020150580A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200261726A1 (en) * | 2017-10-05 | 2020-08-20 | The Board Of Trustees Of The Leland Stanford Junior University | Conductive Polymer Implant, combining electrical and chemical stimulation to improve neural recovery |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050069597A1 (en) * | 1999-07-01 | 2005-03-31 | Thompson Ronald J. | Method of using a compound of menthol and L-arginine as a preparation for the topical delivery of alprostadil for the treatment of female sexual dysfunction |
| US20070178071A1 (en) * | 2003-04-01 | 2007-08-02 | Christof Westenfelder | Stem-cell, precursor cell, or target cell-based treatment of multiorgan failure and renal dysfunction |
| US20100297089A1 (en) * | 2007-07-16 | 2010-11-25 | Il Hoan Oh | Method for promoting the self-renewal of adult stem cells using mesenchymal stromal cells |
| EP3231434A1 (en) * | 2016-04-14 | 2017-10-18 | Fundacio Centre de Regulacio Genomica | Method of treatment of parkinsonism |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003217350A1 (en) * | 2002-02-08 | 2003-09-02 | University Of Chile | Proliferated cell lines and uses thereof |
| US7470538B2 (en) * | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
| US8609082B2 (en) * | 2005-01-25 | 2013-12-17 | Bio Control Medical Ltd. | Administering bone marrow progenitor cells or myoblasts followed by application of an electrical current for cardiac repair, increasing blood supply or enhancing angiogenesis |
| US11707488B2 (en) * | 2015-08-28 | 2023-07-25 | Rohto Pharmaceutical Co., Ltd. | ROR1-positive mesenchymal stem cells and method for preparing same, pharmaceutical composition containing ROR1-positive mesenchymal stem cells and method for preparing same, and method for preventing or treating disease using ROR1-positive mesenchymal stem cells |
-
2020
- 2020-01-17 CA CA3127090A patent/CA3127090A1/en active Pending
- 2020-01-17 US US17/417,289 patent/US20220072050A1/en not_active Abandoned
- 2020-01-17 JP JP2021537075A patent/JP2022517531A/ja active Pending
- 2020-01-17 WO PCT/US2020/014041 patent/WO2020150580A1/en not_active Ceased
- 2020-01-17 EP EP20740959.0A patent/EP3911342A4/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050069597A1 (en) * | 1999-07-01 | 2005-03-31 | Thompson Ronald J. | Method of using a compound of menthol and L-arginine as a preparation for the topical delivery of alprostadil for the treatment of female sexual dysfunction |
| US20070178071A1 (en) * | 2003-04-01 | 2007-08-02 | Christof Westenfelder | Stem-cell, precursor cell, or target cell-based treatment of multiorgan failure and renal dysfunction |
| US20100297089A1 (en) * | 2007-07-16 | 2010-11-25 | Il Hoan Oh | Method for promoting the self-renewal of adult stem cells using mesenchymal stromal cells |
| EP3231434A1 (en) * | 2016-04-14 | 2017-10-18 | Fundacio Centre de Regulacio Genomica | Method of treatment of parkinsonism |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3911342A1 (en) | 2021-11-24 |
| WO2020150580A1 (en) | 2020-07-23 |
| EP3911342A4 (en) | 2022-11-09 |
| US20220072050A1 (en) | 2022-03-10 |
| CA3127090A1 (en) | 2020-07-23 |
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