JP2022094377A - Syringe and management device - Google Patents

Abstract

To enable the measurement of an injection amount by a simple operation and to enable the management of an injection amount and an injection time of an injection drug to be injected.SOLUTION: In an injection cylinder, a tip side in an axial direction is arranged in a liquid medicine filling space of an injection cylinder part in a liquid-tight state, a rear end face is arranged so as to come into contact with a tip face of a pressure cylinder fixed at a prescribed position, and is further made movable along the axial direction, a stopper is arranged at a position corresponding to the injection amount of the liquid medicine to an object person by a rotation operation of a gear part, a detection part detects rotation information relating to the rotation operation, and the liquid medicine filled into the injection cylinder part is injected into the object person by releasing a fixed state of the pressure cylinder fixed at the prescribed position by operating a release part, and displacing the pressure cylinder to the tip part side until coming into contact with the stopper according to elastic force of an elastic member to displace the injection cylinder to the tip side of the injection cylinder part.SELECTED DRAWING: Figure 1

Description

The present invention relates to a needleless syringe for injecting a drug solution into a subject, and a management device for managing injections using the syringe.

In diabetic patients, diabetic therapy is carried out in which a drug solution such as insulin is self-injected with a special syringe to allow the patient to self-control the blood glucose level. In addition to the syringes shown in Patent Document 1 below, there are various types of syringes to which this therapy is adopted, and most of them have extremely thin injection needles, and the injection drug is also a container called Vital (5 ml). The patient purchases and stores (stores in the refrigerator) what is contained in (10 ml, etc.) based on the prescription, and at the time of injection, the patient fills the syringe with the injection drug contained in the vital and pierces the injection needle subcutaneously. And self-injection is adopted.

Japanese Unexamined Patent Publication No. 2004-555

Regarding self-injection of insulin, etc. by diabetic patients, for example, the Japan Association for Diabetes Science has formulated a guide for injection methods, and patients use the purchased syringe to fill the syringe with the injection drug prescribed by the doctor at each injection. A self-injection method is adopted based on such a guide.

In this way, when the patient self-injects insulin, etc., the patient measures his / her blood glucose level at the required time, and at what time of the day, how much injection drug (insulin, etc.) is used. ) I try to decide for myself whether to inject. For example, the blood glucose level is measured before and after meals, and the injectable drug filled in the syringe is injected from the vital container (5 ml, 10 ml, etc.) in the required amount at the required time in several divided doses, and the blood glucose level is set by itself. Control therapy was taken. However, it is very troublesome for such a self to record the injection time and injection amount of the injectable drug each time.

Therefore, the present invention makes it possible to measure the injection amount of an injection drug (drug solution) by a simple operation, and injects with an injection device and the injection device that can control the injection amount and injection time of the injection drug to be injected by the injection. It is intended to provide an injectable drug management device.

In order to solve the above problems, the syringe of the present invention includes a substantially cylindrical main body having an internal space and a pressing cylinder arranged in the main body so that the central axis rests on the axis of the central axis of the main body. , An injection cylinder provided at the tip of the main body in the direction of the axis, and an elastic member provided in the main body to urge the pressing cylinder toward the tip in the direction of the axis. A pressing cylinder fixing mechanism that fixes the cylinder at a predetermined position at the rear end in the direction of the axis of the main body, a releasing part that releases the fixed state by the pressing cylinder fixing mechanism, and a centering axis with respect to the main body. A gear part that is provided so that it can rotate relative to each other, a stopper that is provided inside the main body and is made movable along the axis by the rotation of the gear part, and a stopper that regulates the range of displacement of the pressing cylinder in the internal space, and a gear. It is equipped with a detection unit that detects rotation information including the rotation angle and rotation direction of the unit, and an injection cylinder. The rear end side is arranged in an airtight state in the internal space, and the rear end surface is arranged so as to abut on the tip surface of the pressing cylinder fixed at a predetermined position, and further moves along the direction of the axis. It is possible, by rotating the gear part, the stopper is placed at the position corresponding to the injection amount of the drug solution to the subject, and the detection part detects the rotation information related to this rotation operation and operates the release part. By releasing the fixed state of the pressing cylinder fixed at the predetermined position, the injection cylinder is displaced toward the tip end side until it abuts on the stopper according to the elastic force of the elastic member. By shifting to the tip side of the syringe barrel, the drug solution filled in the syringe barrel is injected into the subject.

In the injector of the present invention, the gear portion includes an annular magnetic portion that rotates around the axis along with the rotation of the gear portion, and the detection unit provides rotation information of the gear portion based on the change in the magnetic field distribution due to the rotation of the magnetic portion. It is preferable to detect.

In the syringe of the present invention, it is preferable that the position of the stopper is set according to the amount of the drug solution to be injected into the subject.

The syringe of the present invention includes a communication unit capable of transmitting and receiving a signal to and from an external device, and the communication unit transmits the rotation angle detected by the detection unit to the external device when the release unit is operated. Is preferable.

The management device of the present invention has a communication unit that enables mutual communication with the above-mentioned injection device, a calculation unit that calculates the amount of the drug solution injected into the subject based on the rotation angle, and a drug solution for the subject. A storage unit that stores injection information related to injection and stores the amount of drug solution calculated by the calculation unit in association with time information, injection information, and the amount of drug solution calculated by the calculation unit, and associated with this. It is characterized by having a management unit that manages the next injection time and the amount of the drug solution at the time of this injection based on the time information.

The management device of the present invention is preferably composed of a communication unit, a calculation unit, a storage unit, and a mobile information terminal having a function corresponding to each of the management unit.

The management device of the present invention preferably includes a warning unit for notifying the next injection time.

According to the present invention, a syringe capable of measuring the injection amount of a drug solution (injection drug) by a simple operation, and management capable of controlling the injection amount and injection time of the drug solution to be injected into a subject by the injection. Equipment can be provided.

It is a perspective view which shows the structure of the syringe which concerns on embodiment of this invention. (A), (b), and (c) are cross-sectional views taken along the axial direction of the syringe of FIG. (A) is an enlarged view of the rear end portion of FIG. 2 (c), and (b) is a cross-sectional view taken along the line 3B-3B'of (a). (A) and (b) are sectional views along the axial direction of the syringe of FIG. (A) is a perspective view showing the relationship between the injection cylinder, the injection tube, the adapter, and the drug solution container, and (b) is a state in which the injection cylinder, the injection tube, and the drug solution container are connected to each other via the adapter. The cross-sectional view shown, (c) is a cross-sectional view showing a state in which the injection cylinder 100 is moved from the state of (b) to fill the injection cylinder portion with the drug solution. (A) is a cross-sectional view showing a state before the injection cylinder and the injection cylinder portion are pushed into the main body of the syringe with the adapter connected to the tip portion, and (b) is the injection cylinder from the state of (a). It is a cross-sectional view which shows the state which pushed the rear end side into the internal space of a syringe, and (c) is the cross-sectional view which shows the state which the adapter was removed from the state of (b). (A) is a partially enlarged view of FIG. 6 (c), and (b) is a cross-sectional view showing a state in which the stopper is pulled up toward the rear end portion from the state of (a). (A) is a partially enlarged perspective view of FIG. 7 (b), and (b) is a perspective view showing an external configuration in the vicinity of the grip portion of the syringe. (A) is a perspective view showing the appearance configuration of the rear end portion of the syringe shown in FIG. 1, and (b) is a cross-sectional view taken along the direction of the axis of the rear end portion of (a). It is sectional drawing which shows the structure in the internal space in the vicinity of a gear part. (A) is a cross-sectional view along the direction of the axis corresponding to the state of FIG. 6 (c), and (b) is a state in which the injection is performed by operating the release button (release portion) from the state of (a). It is sectional drawing which shows. (A), (b), (c), (d) are cross-sectional views along the axial direction showing the next injection step of the injection shown in FIG. 11 (b). It is a functional block diagram of the management device including a syringe. It is a flowchart which shows the flow of injection using a syringe and a management device. It is a flowchart which shows the flow which follows FIG. It is a flowchart which shows the flow which follows FIG.

Hereinafter, the syringe and the management device according to the embodiment of the present invention will be described in detail with reference to the drawings.
The syringe 10 according to the present embodiment has a main body portion 20, a pressing cylinder 30, a grip portion 40, and a coil as an elastic member, as shown in FIGS. 1 or 2 (a), (b), and (c). It includes a spring 50, a pressing cylinder fixing mechanism 60, a release button 70 as a release portion, a gear portion 80, a stopper 90, an injection cylinder 100, and an injection cylinder portion 110. As shown in FIG. 13, the syringe 10 further includes a detection unit 120 and a communication unit 130.

Here, FIGS. 2A, 2B, 2C and 4A, 4B show a state before the injection cylinder 100 is pushed into the internal space 21. In FIG. 2, from the initial state of (a), the pressing cylinder 30 is turned to the rear end side by turning the grip portion 40 counterclockwise around the axis AX of the central axis, looking from the D2 side to the D1 side. The process of pulling up to (D2 side) is shown. In (c), the cylinder stopper 32 at the rear end of the pressing cylinder 30 is fixed at a predetermined position P1 (see FIG. 3A) by the pressing cylinder fixing mechanism 60. Has been done. In FIG. 4, from the state corresponding to FIG. 2 (c), the pressing cylinder 30 is turned at the tip of the pressing cylinder 30 by turning the grip portion 40 clockwise around the axis AX of the central axis, looking from the D2 side to the D1 side. It shows the state of being lowered to the side (D1 side).

Further, FIGS. 12 (a), 12 (b), (c), and (d) are cross-sectional views showing a step of the next injection of the injection shown in FIGS. 11 (a) and 11 (b), and is a cross-sectional view showing the injection tube portion. The step of injecting the drug solution remaining in 110 is shown. In FIG. 12A, the pressing cylinder 30 is pulled up to the rear end portion 12 side (D2 side) and fixed to the pressing cylinder fixing mechanism 60 with respect to the state at the end of the previous injection (FIG. 11B). There is. In FIGS. 12 (b) to 12 (c), the stopper 90 is lowered to a position corresponding to the amount of the chemical solution injected by the rotation of the gear portion 80. Then, FIG. 12C shows a state in which the drug solution is injected into the target site T by operating the release button 70.

As shown in FIG. 13, the syringe 10 is configured to be communicable with the management device 140, which is an external device, and the management device 140 stores the communication unit 141, the management unit 142, the calculation unit 143, and the storage unit 140. A unit 144, a display unit 145, an input unit 146, and a warning unit 147 are provided.

<Syringe 10>
The members constituting the syringe 10 are preferably made of a material that is easy to sterilize and has high antibacterial properties. Further, it is preferable in terms of hygiene that the injection cylinder 100 and the injection cylinder portion 110 are made of a material having durability against a chemical solution and further made of a disposable material. Furthermore, it is preferable that the syringe 10 is made of a lightweight material having portability as a whole.

As shown in FIG. 2, the main body portion 20 has a substantially cylindrical shape having an internal space 21 extending along the axis AX of the central axis thereof. Here, in the following description, the direction in the D1 direction (downward in FIGS. 2A, 2B, 2C) along the direction of the axis AX shown in FIGS. 1 and 2 is the tip 11 side. The direction in the D2 direction (upward in FIGS. 2A, 2B, and 2C) is referred to as the rear end portion 12 side.

A cylindrical pressing cylinder 30 is arranged in the main body 20 so as to be movable along the direction of the axis AX. The pressing cylinder 30 is arranged so that its central axis is placed on the axis AX of the main body portion 20. The tip portion 31 of the pressing cylinder 30 has a disk shape centered on the position of the axis AX, and the tip surface 33 thereof is exposed in the internal space 21.

A flange-shaped cylinder stopper 32 extending in the radial direction from the position of the axis AX is provided at a predetermined position on the rear end side of the pressing cylinder 30. As shown in FIG. 3A, a protrusion 32a projecting outward in the radial direction is provided on the outer edge of the cylinder stopper 32.

As shown in FIGS. 1 and 2 (a), (b), and (c), a grip portion 40 is provided at the rear end portion (end portion on the D2 side) of the main body portion 20. The grip portion 40 has a hollow cylindrical shape in which the central axis extends along the axis AX. As shown in FIGS. 4A and 4B, the grip portion 40 has an outer cylinder portion 41 rotatable about the axis AX and an inner cylinder portion 41 arranged along the inner peripheral surface of the outer cylinder portion 41. A cylinder portion 42 is provided. On the outer peripheral surface of the inner cylinder portion 42, a spiral groove portion (not shown) that meshes with the spiral groove portion (not shown) formed on the inner peripheral surface of the outer cylinder portion 41 is formed. Therefore, the inner cylinder portion 42 moves toward the outer cylinder portion D1 direction) or the rear end side (D2 direction).

The inner peripheral surface of the inner cylinder portion 42 forms an accommodating space 43 connected to the internal space 21 of the main body portion 20, and the rear end portion side of the pressing cylinder 30 is accommodated in the accommodating space 43.

A coil spring 50 as an elastic member is accommodated in the accommodation space 43. The coil spring 50 is wound around the outer peripheral surface of the pressing cylinder 30, the tip of which is fixed to the tip portion 31 of the pressing cylinder 30, and the rear end is fixed to the inner surface of the inner cylinder portion 42 on the rear end side. ing.

The tip end side of the pressing cylinder 30 extends from the inner cylinder portion 42, and the extending amount thereof changes due to expansion and contraction of the coil spring 50. On the other hand, since the tip portion 31 of the pressing cylinder 30 has an outer diameter larger than the inner diameter of the accommodation space 43, when the pressing cylinder 30 moves relatively to the rear end portion 12 side with respect to the inner cylinder portion 42, The relative movement of the pressing cylinder 30 is restricted by the abutting of the tip portion 31 with the inner cylinder portion 42. Therefore, the tip portion 31 is always located outside the inner cylinder portion 42 regardless of the expansion / contraction state of the coil spring 50. With such a configuration, the coil spring 50 can urge the pressing cylinder 30 toward the tip portion 11 in the direction of the axis AX.

As shown in FIGS. 1 and 2 (a), (b), and (c), a pressing cylinder fixing mechanism 60 is provided at the rear end of the grip portion 40. As shown in FIGS. 3A and 3B, the pressing cylinder fixing mechanism 60 has a configuration in which four slide stoppers 62 are provided in a hollow and substantially cylindrical tubular body 61. The four slide stoppers 62 are provided at equal intervals with respect to the inner peripheral surface of the tubular body 61 with respect to the axis AX. Since the four slide stoppers 62 are arranged via the four pressing springs 63 fixed to the inner peripheral surface of the tubular body 61, the four slide stoppers 62 are arranged inside the tubular body 61, that is, in the direction approaching the axis AX. Each is urged.

As shown in FIG. 3 (b), the tubular body 61 is formed with a substantially circular space 64 surrounded by four slide stoppers 62 in a plan view along the axis AX, and the space 64 is filled with a substantially circular space 64. , The tip portion 71 of the release button 70 as the release portion is inserted. The release button 70 has a tip portion 71 having a tapered columnar shape, and is provided with respect to the tubular body 61 via a support spring 72. Therefore, the operation surface 73, which is the rear end surface of the release button 70, extends from the rear end surface of the tubular body 61 due to the elastic force of the support spring 72 (see FIG. 9). On the other hand, by pushing the operation surface 73 toward the tip end side (D1 side) against the elastic force of the support spring 72, the release button 70 can be pushed down inside the tubular body 61. Since the tip portion 71 of the release button 70 has a shape in which the outer diameter increases as it approaches the operation surface 73, when the release button 70 is pushed down, four slide stoppers 62 are formed according to the inclined shape of the tip portion 71. , Spread along the radial direction with respect to the axis AX.

The four slide stoppers 62 are also expanded along the radial direction with respect to the axis AX by raising the pressing cylinder 30 along the D2 direction. That is, first, when the pressing cylinder 30 is raised, the protrusion 32a of the cylinder stopper 32 comes into contact with the four slide stoppers 62. When the pressing cylinder 30 is further raised from here, the protrusion 32a has an inclined surface whose outer diameter becomes smaller toward the release button 70 side (rear end portion 12 side, D2 direction), so that the slide stopper 62 Is pushed out.

A groove portion 62a formed so as to be recessed outward in the radial direction is provided on the inner peripheral surface of the slide stopper 62. As described above, when the pressing cylinder 30 is raised while expanding the slide stopper 62 and reaches the position of the groove portion 62a, the protrusion 32a of the cylinder stopper 32 fits into the groove portion 62a, and the pressing cylinder 30 is at this position P1 (predetermined). The position is fixed at FIG. 3 (a)). This fixed state is released by removing the protrusion 32a from the groove 62a by the user pushing down the release button 70 from the outside and applying a downward (D1 direction) force to the cylinder stopper 32 by the release button 70.

As shown in FIGS. 2A, 2B, and 2C, a gear portion 80 is provided on the tip end side (D1 direction) of the main body portion 20. The gear portion 80 has a hollow cylindrical shape in which the central axis extends along the axis AX, and is rotatable relative to the main body portion 20 with the axis AX as the center.

A stopper 90 is arranged inside the gear portion 80. The stopper 90 has a hollow cylindrical shape in which the central axis extends along the axis AX. As a result, inside the gear portion 80 and the stopper 90, the front end side is connected to the internal space 21 of the main body portion 20, and the rear end side is connected to the accommodation space 43 of the grip portion 40 to form an internal space 81.

A spiral groove portion (not shown) that meshes with a spiral groove portion (not shown) formed on the inner peripheral surface of the gear portion 80 is formed on the outer peripheral surface of the stopper 90. Therefore, when the gear portion 80 is rotated, the stopper 90 moves toward the front end side (D1 direction) or the rear end side (D2 direction) along the direction of the axis AX according to the rotation direction (FIG. 7). (A), (b)). Since the diameter of the inner peripheral surface of the stopper 90 is set to be smaller than the outer diameter of the tip portion 31 of the pressing cylinder 30, when the pressing cylinder 30 is moved to the tip side (D1 side), it comes into contact with the stopper 90. This regulates the position of the pressing cylinder 30.

By moving the pressing cylinder 30, the injection cylinder 100 (described later) arranged in contact with the tip surface 33 of the pressing cylinder 30 moves. Therefore, by restricting the movement range of the pressing cylinder 30 by the stopper 90, the movement range of the injection cylinder 100 that moves while in contact with the pressing cylinder 30 is also restricted, so that the injection is performed by the movement of the injection cylinder 100. The amount of chemical solution can be specified. As shown in FIG. 8B, a counter 22 is provided on the outer peripheral surface of the main body portion 20, and the displayed numerical value changes according to the rotation amount of the gear portion 80. By this change in the numerical value, the subject can recognize the planned injection amount of the chemical solution.

As shown in FIG. 8A, an annular magnetic disk 82 centered on the position of the axis AX is fixed to the bottom surface of the gear portion 80 on the tip end side as a magnetic portion. The magnetic disk 82 rotates around the axis AX together with the gear portion 80. The magnetic disk 82 distributes magnetism so that the distribution of the generated magnetic field changes with rotation. For example, the magnetic poles of the axis AX are configured to be different at equal intervals.

A detection unit 120 (encoder) capable of detecting a change in magnetism is provided on the D1 side (tip portion 11 side) of the magnetic disk 82. The detection unit 120 detects a magnetic field distribution (rotation information) that changes according to the rotation direction and rotation angle when the magnetic disk 82 rotates with the rotation of the gear unit 80, and is a Hall element or other magnetic sensor. Can be used. The detection result is output to the control unit 121 (see FIG. 13).

As shown in FIG. 10, an annular substrate 23 arranged so as to be orthogonal to the axis AX is provided in the internal space 21 in the vicinity of the gear portion 80. A light emitting diode 122 (LED) and a phototransistor 123 are arranged on the substrate 23 with the axis AX interposed therebetween. The light emitting diode 122 emits inspection light toward the axis AX side of the central axis according to the control signal from the control unit 121, and the transmitted light transmitted through the injection cylinder 100 is incident on the phototransistor 123. The detection signal by 123 is input to the control unit 121 as shown in FIG.

As will be described later, the injection cylinder 100 is inserted along the direction of the axis AX of the central axis in the region where the light emitting diode 122 and the phototransistor 123 face each other, and can move along the direction of the axis AX of the central axis. It is said that. In the injection cylinder 100, a groove portion 101a centered on the axis AX of the central axis is provided on the outer peripheral surface of the substantially columnar main body portion 101. The groove portion 101a has convex portions and concave portions formed at regular intervals in the direction of the axis AX of the central axis. The inspection light emitted from the light emitting diode 122 has different results detected by the phototransistor 123 due to the difference in the shape of the convex portion and the concave portion of the groove portion 101a. Further, the control unit 121 is the main body of the injection cylinder 100 based on the relationship between the convex and concave portions of the groove 101a and the change in the detection signal due to the time change of the detection signal of the phototransistor 123 from the operation of the release button 70. The moving distance of the 101 (the number of convex portions and concave portions of the groove portion 101a) can be calculated. This makes it possible to confirm whether or not a predetermined amount of chemical solution is ejected depending on the position of the stopper 90.

As shown in FIGS. 5 (b) and 6 (a), (b), and (c), the injection cylinder 100 includes a substantially cylindrical main body portion 101 and a cylindrical head portion 102 extending from the main body portion 101. Equipped with. The main body portion 101 and the head portion 102 extend around the same axis, the main body portion 101 has a groove portion 101a on the outer peripheral surface, and the head portion 102 has an outer diameter smaller than that of the recess of the groove portion 101a.

As shown in FIGS. 6 (b) and 6 (c), the injection cylinder 100 is arranged in the internal space 21 of the syringe 10. In the internal space 21, the rear end surface 103 of the main body 101 is arranged so as to abut on the tip surface 33 of the pressing cylinder 30 in the internal space 21, and the front end 102 extends outward from the tip 11 of the syringe 10. do. Since the injection cylinder 100 is in contact with the pressing cylinder 30, when the pressing cylinder 30 is moved to the tip 11 side (D1 side), it moves together with the pressing cylinder 30. At this time, the main body 101 moves along the direction of the axis AX of the central axis while maintaining an airtight state with respect to the inner peripheral surface of the internal space 21.

As shown in FIGS. 5 (b) and 6 (a), (b), and (c), the head portion 102 of the injection cylinder 100 is arranged in the chemical solution filling space 111 inside the cylindrical injection cylinder portion 110. It is made movable along the direction of the central axis of the syringe barrel 110 in a liquid-tight state.

When filling the chemical solution filling space 111 of the injection tube portion 110 with the chemical solution, the injection tube portion 110 is connected to the chemical solution container 210 via the adapter 200 as shown in FIG. 5 (a). As shown in FIG. 5B, in the adapter 200, a hollow needle portion 201 that enables circulation of the chemical solution between the tip portion 104 of the leading portion 102 of the injection cylinder 100 and the chemical solution container 210 is provided. It is provided. By screwing the syringe barrel 110 into the adapter 200, the space inside the needle 201 and the tip 104 communicate with each other in an airtight state, and further, by screwing the adapter 200 into the chemical container 210, the needle 201 The tip of the needle reaches the inside of the chemical solution filled in the chemical solution container 210. As a result, the space inside the tip portion 104 and the inside of the chemical solution container 210 communicate with each other via the needle portion 201.

As shown in FIG. 5 (b), the injection cylinder is in the direction in which the tip portion 104 is separated from the adapter 200 as shown in FIG. When 100 is moved, the chemical solution filling space 111 of the injection cylinder portion 110 becomes a negative pressure, so that the chemical solution is sucked up from the chemical solution container 210 into the chemical solution filling space 111. By moving the tip portion 104 of the injection cylinder 100 to a predetermined position in the injection cylinder portion 110, a constant amount of the chemical solution is filled in the chemical solution filling space 111 of the injection cylinder portion 110.

When a certain amount of the chemical solution is filled as described above, the chemical solution container 210 is removed. Then, as shown in FIG. 6A, the injection cylinder 100 in the state where the adapter 200 and the injection cylinder portion 110 are connected is pushed into the internal space 21 of the syringe 10 from the rear end surface 103, and is pushed into the internal space 21 of the syringe 10 (b). ), The rear end surface 103 is arranged at a position where it abuts on the front end surface 33 of the pressing cylinder 30. Further, as shown in FIG. 6C, the adapter 200 is removed, the gear portion 80 is rotated, and then the release button 70 is operated to eject a predetermined amount of the chemical solution in the syringe barrel portion 110. ..

<Management device 140>
Next, the management device 140 will be described with reference to FIG. The management device 140 includes a communication unit 141 that enables mutual transmission and reception with the communication unit 130 of the syringe 10. Any communication standard can be appropriately applied to these communication units 130 and 141 by wireless and wired in consideration of the assumed communication distance, cost and the like. For example, when an individual has a syringe 10 and a management device 140, it is preferable to use Bluetooth (registered trademark) because it is used at a relatively short distance.

The management device 140 includes a management unit 142 and an input unit 146, and the management unit 142 controls the communication unit 141, the calculation unit 143, and the storage unit 144, as well as injection information and a calculation unit. Based on the amount of the drug solution and the time information associated with the drug solution, the time of the next injection and the amount of the drug solution at the time of this injection are managed, and these information are stored in the storage unit 144.

The injection information is input by the subject operating the input unit 146 and stored in the storage unit 144. The injection information includes, for example, the subject's age, gender, height, body weight, type of drug solution, planned daily dose of drug solution, number of times of administration per day, scheduled dose per dose, and corresponding counter. The amount of change in the numerical value in 22 and the scheduled administration time are included.

The detection result by the detection unit 120 of the syringe 10 is transmitted from the communication unit 130 to the communication unit 141 of the management device 140 under the control of the control unit 121. For the transmitted detection result, the calculation unit 143 calculates the rotation direction and rotation angle of the gear unit 80 based on the change in the magnetic field distribution as the detection result, and the chemical solution injected from these rotation directions and rotation angles. , That is, the amount of the drug solution injected into the subject is calculated. This calculation result is stored in the storage unit 144 and displayed on the display unit 145.

The warning unit 147 gives a warning to notify the next injection time, for example, after the injection. Further, the scheduled injection amount of the chemical solution calculated from the rotation angle of the gear unit 80 is compared with the injection information stored in the storage unit 144, and the predetermined injection amount is predetermined with respect to the scheduled injection amount in the injection information. When a difference of more than ± 10%, for example, is observed, a warning message is displayed on the display unit 145 so as to review the rotation setting in the gear unit 80. This makes it possible to prevent an error in the dose of the drug solution due to an erroneous operation of the gear portion 80 in advance.

The warning by the warning unit 147 is given by, for example, the generation of an alarm sound. Further, a warning signal can be output to the management unit 142, and an alarm can be displayed on the display unit 145 based on the warning signal.

The management device 140 can be configured by applying dedicated software (application, application) to, for example, a mobile information terminal or a personal computer (PC) in addition to the dedicated device. As the mobile information terminal, for example, a smartphone, one having a function corresponding to the communication unit 141, the management unit 142, the calculation unit 143, the storage unit 144, the display unit 145, the input unit 146, and the warning unit 147 is used. Can be done.

Subsequently, with reference to FIGS. 14 to 16, an example of the flow of processing using the syringe 10 and the management device 140 will be described. Steps S11 to S29 on the left side of FIGS. 14 to 16 show processing in the syringe 10, and steps S41 to S53 on the right side show processing in the management device 140 (smartphone, PC, etc.).

In the management device 140, the application (software) is started (step S41), and the required insulin injection amount and the required number of injections are set as injection information by operating the input unit 146 (step S42). Further, by operating the input unit 146, an alarm notification setting for the injection time is set according to the lifestyle of the user (target person) (step S43). As this setting, for example, a working subject may set the rest time or the time before and after the work as the injection time.

On the other hand, as an operation on the syringe 10 side, the pressing cylinder 30 is pulled up by rotating the grip portion 40, and the pressing cylinder 30 is fixed by the pressing cylinder fixing mechanism 60 (step S11).

Further, the entire amount of insulin as a drug solution is inhaled from the drug solution container 210 into the syringe barrel portion 110 that has not been inserted into the main body portion 20 (step S12). For this inhalation, first, as shown in FIG. 5A, the injection cylinder portion 110 in which the injection cylinder 100 is inserted is screwed into the adapter 200, and further, the chemical liquid container 210 is screwed into the adapter 200. .. As a result, the syringe barrel portion 110 communicates with the chemical liquid container 210 via the needle portion 201 (FIG. 5 (b)). From this state, insulin is sucked into the chemical solution filling space 111 by pulling up the injection cylinder 100 in a direction away from the chemical solution container 210. When the inhalation is completed in this way, the chemical solution container 210 is removed from the adapter 200.

After the above steps S11 to 12 and S41 to 43, the management device 140 enters the standby mode (step S44). After that, when the injection time set in step S43 is reached, an alarm is notified (step S45). Further, the Bluetooth (registered trademark) of the communication unit 141 on the management device 140 side is set to the ON state.

When the subject activates the syringe 10 in response to the notification in step S45 (step S13), the Bluetooth (registered trademark) of the communication unit 130 is turned on (step S14), and the Bluetooth (registered trademark) is turned on (step S14) with the management device 140. Communication by the registered trademark) is possible (steps S15 and S46). As a result, in the management device 140, it is detected in the application that the power of the syringe 10 is turned on (step S47).

After starting the syringe 10 in step S13, the subject is in a state where the injection cylinder portion 110 inhaled insulin in step S12 and the injection cylinder 100 and the adapter 200 connected to the injection cylinder portion 110 remain integrated (FIG.). 6 (a)), the injection cylinder 100 is pushed into the internal space 21 of the main body 20 of the syringe 10 (FIG. 6 (b)). Here, the pressing cylinder 30 is pulled down to the injection standby position by the rotation of the grip portion 40 after the cylinder stopper 32 is fixed by the pressing cylinder fixing mechanism 60 (the same state as in FIG. 4B), and the injection cylinder 30 is injected. The 100 is arranged at a position where the rear end surface 103 abuts on the front end surface 33 of the pressing cylinder 30 (FIG. 6 (b)). After this, as shown in FIG. 6 (c), the adapter 200 is in a removed state.

Here, the injection cylinder 100 may be inserted into the internal space 21 in the standby mode of step S44. Further, the injection cylinder 100 may be inserted into the internal space 21 after the rotation of the gear portion 80 and before the operation of the release button 70.

Next, the subject rotates the gear portion 80 in order to set the injection amount of the chemical solution. The rotation amount of the gear unit 80 is set according to the amount of insulin to be injected at that time, and the amount of change in the numerical value of the counter 22 corresponding to the rotation amount is displayed on the display unit 145. The subject rotates the gear unit 80 so that the number displayed on the counter 22 changes by the number displayed on the display unit 145. The specific processing procedure at this time is as follows.

First, in step S12, the entire amount of insulin is inhaled from the drug solution container 210 into the injection cylinder portion 110, and this state is maintained, and the injection cylinder 100 is pushed into the internal space 21 until it comes into contact with the pressing cylinder 30. When injection is performed from this state without rotating the gear portion 80 (NO in step S16), 100% (initial value) of insulin in the syringe barrel portion 110 is injected (step S48). On the other hand, when the gear portion 80 is rotated, the amount of movement of the pressing cylinder 30 and the injection cylinder 100 is reduced by the amount of rotation, so that the amount of insulin to be ejected is also reduced.

When the gear portion 80 rotates (YES in step S16), the magnetic disk 82 rotates together with the gear portion 80 (step S17), and the surrounding magnetic field distribution changes according to the rotation direction and rotation angle of the magnetic disk 82.

The change in the magnetic field distribution due to the rotation of the magnetic disk 82 is detected by the magnetic sensor of the detection unit 120 (rotary encoder) (step S18) and transmitted to the management device 140.

In the management device 140, the pulse in the pulse signal indicating the change in the magnetic field distribution with the passage of time is counted (step S19), and the rotation direction and the rotation angle of the gear unit 80 are calculated based on the count number (step S20). The rotation direction and rotation angle (rotation angle position data) calculated in this way are transmitted to the management device 140 side (steps S21 and S49).

When the above steps are completed, the light emitting diode 122 (LED) in the syringe 10 starts emitting light (step S22), and the search light from the light emitting diode 122 is received by the phototransistor 123 (step S23).

For the light emission of the light emitting diode 122, a signal instructing the light emission of the light emitting diode 122 is output to the injector 10 side by operating the input unit 146 of the management device 140 immediately before the operation of the release button 70. The light emitting diode 122 may be made to emit light accordingly.

Next, the release button 70 is pressed while the syringe barrel 110 of the syringe 10 is in contact with the injection site T (see FIG. 11B) (step S24). By this operation, the fixed state by the pressing cylinder fixing mechanism 60 is released, and the pressing cylinder 30 moves toward the tip portion 104 (step S25). Along with the movement of the pressing cylinder 30, the injection cylinder 100 in contact with the pressing cylinder 30 also moves (step S25), the chemical solution in the syringe barrel 110 is ejected, and injection is performed.

Due to the movement of the injection cylinder 100 in step S25, the transmitted light transmitted through the injection cylinder 100 by the inspection light from the light emitting diode 122 is incident on the phototransistor 123. The amount of transmitted light changes according to the uneven shape of the groove 101a provided in the injection cylinder 100, and the phototransistor 123 detects the change in the amount of transmitted light (step S26).

The result of the change in the amount of transmitted light detected by the phototransistor 123 is transmitted to the management device 140 (steps S27 and S50). The calculation unit 143 of the management device 140 is based on the detection result by the phototransistor 123 and the detection result by the detection unit 120. The amount of the injected chemical solution is calculated and stored in the storage unit 144 together with the time of injection (step S51).

The injection chemical amount calculated in step S51 is displayed on the display unit 145. The display unit 145 indicates that the syringe 10 is urged to turn off after confirming the amount of the injection drug solution. When the syringe 10 is turned off in accordance with this, the communication unit 130 (Bluetooth (registered trademark)) of the syringe 10 is also turned off (step S29), and the communication with the management device 140 is cut off (step S52). Then, the management device 140 shifts to the application standby mode of waiting until the next alarm time (step S53).

A modified example will be described below.
In the above-described embodiment, the magnetic disk 82 is provided in the gear portion 80 as the magnetic portion, but other configurations may be used as long as the magnetic field distribution changes due to the rotation of the gear portion 80. For example, the gear portion 80 itself may be made of a magnetic material having different magnetic poles at equal intervals with respect to the axis AX.

In the above embodiment, the distribution of the magnetic field due to the rotation of the magnetic disk 82 is detected by the detection unit 120, but instead of this, it may be detected by optical means. For example, instead of the magnetic disk 82, an optical disk having different optical characteristics, for example, reflectance, transmittance, and color at equal intervals with respect to the axis AX is used, and the inspection light from the light emitting portion reaches the optical disk. The change in optical characteristics caused by this may be detected. This makes it possible to use even when a device that generates a magnetic field cannot be used.

In the above embodiment, the syringe 10 and the management device 140 can be transmitted and received by Bluetooth (registered trademark) (registered trademark), but these can be communicated by a peer-to-peer method, and the detection data on the syringe 10 side can be communicated. Is transmitted and received as a code signal, so that the communication capacity can be suppressed to a small size, so that the communication unit 130 on the syringe 10 side can be made small and low cost.
Although the present invention has been described with reference to the above embodiments, the present invention is not limited to the above embodiments, and can be improved or modified within the scope of the purpose of improvement or the idea of the present invention.

10 Syringe 11 Syringe tip 12 Syringe rear end 20 Main body 21 Internal space 22 Counter 23 Board 30 Pressing cylinder 31 Pressing cylinder tip 32 Cylinder stopper 32a Protrusion 33 Pressing cylinder tip 40 Grip 41 Outer cylinder Part 42 Inner cylinder part 43 Accommodation space 50 Cylinder spring 60 Pressing cylinder fixing mechanism 61 Cylindrical body 62 Slide stopper 62a Groove part 63 Pressing spring 64 Space 70 Release button 71 Release button tip 72 Support spring 73 Operation surface 80 Gear part 81 Inside Space 82 Magnetic disk 90 Stopper 100 Injection cylinder 101 Main body 101a Groove 102 Head 103 Rear end 104 Tip 110 Syringe 111 Chemical filling space 120 Detection 121 Control 122 Light emitting diode (LED)
123 Phototransistor 130 Communication unit 140 Management device 141 Communication unit 142 Management unit 143 Calculation unit 144 Storage unit 145 Display unit 146 Input unit 147 Warning unit 200 Adapter 201 Needle unit 210 Chemical solution container AX Central axis axis

Claims (7)

A substantially cylindrical body with an internal space,
A pressing cylinder arranged in the main body so that the central axis rests on the axis of the central axis of the main body,
An injection tube portion provided at the tip of the main body portion in the direction of the axis and provided with a chemical solution filling space, and an injection tube portion.
An elastic member provided in the main body and urging the pressing cylinder toward the tip in the direction of the axis.
A pressing cylinder fixing mechanism for fixing the pressing cylinder at a predetermined position at a predetermined position at the rear end portion in the direction of the axis of the main body, and a pressing cylinder fixing mechanism.
A release unit that releases the fixed state by the pressing cylinder fixing mechanism, and
A gear portion provided so as to be rotatable relative to the main body portion about the axis line, and a gear portion.
A stopper provided in the main body portion, which is made movable along the axis by the rotation of the gear portion, and which regulates the range of displacement of the pressing cylinder in the internal space.
A detection unit that detects rotation information including the rotation angle and rotation direction of the gear unit,
With the injection cylinder,
Is a syringe equipped with
In the injection cylinder, the tip end side in the direction of the axis is arranged in a liquidtight state in the chemical solution filling space of the injection cylinder portion, the rear end portion side is arranged in an airtight state in the internal space, and the rear end surface is Is arranged so as to abut on the tip surface of the pressing cylinder fixed at the predetermined position, and is further movable along the direction of the axis.
By the rotation operation of the gear unit, the stopper is arranged at a position corresponding to the injection amount of the drug solution to the target person, and the detection unit detects the rotation information related to the rotation operation.
By operating the release portion, the fixed state of the pressing cylinder fixed at the predetermined position is released, and the pressing cylinder is brought into contact with the stopper according to the elastic force of the elastic member. By shifting the injection cylinder toward the tip of the syringe, the injection cylinder is displaced toward the tip of the syringe, so that the drug solution filled in the syringe can be injected into the subject. Syringe. The gear portion includes an annular magnetic portion that rotates around the axis along with its rotation.
The syringe according to claim 1, wherein the detection unit detects the rotation information of the gear unit based on a change in the magnetic field distribution due to the rotation of the magnetic unit. The syringe according to claim 1 or 2, wherein the position of the stopper is set according to the amount of the drug solution to be injected into the subject. Equipped with a communication unit that enables transmission and reception of signals with external devices
The syringe according to any one of claims 1 to 3, wherein the communication unit transmits the rotation angle detected by the detection unit to the external device when the release unit is operated. A communication unit that enables mutual communication with the syringe according to claim 4.
A calculation unit that calculates the amount of the drug solution injected into the subject based on the rotation angle, and
A storage unit that stores injection information regarding injection of the drug solution to the subject and stores the amount of the drug solution calculated by the calculation unit in association with time information.
Based on the injection information, the amount of the drug solution calculated by the calculation unit, and the time information associated with the injection information, the management unit that manages the next injection time and the amount of the drug solution at the time of this injection. A management device characterized by being provided with. The management device according to claim 5, wherein the management device includes a communication unit, a calculation unit, a storage unit, and a mobile information terminal having a function corresponding to each of the management units. The management device according to claim 5 or 6, further comprising a warning unit for notifying the next injection time.

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