JP2021526791A - セルフリー核酸の細胞起源を決定するための方法およびシステム - Google Patents

セルフリー核酸の細胞起源を決定するための方法およびシステム Download PDF

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JP2021526791A
JP2021526791A JP2020567550A JP2020567550A JP2021526791A JP 2021526791 A JP2021526791 A JP 2021526791A JP 2020567550 A JP2020567550 A JP 2020567550A JP 2020567550 A JP2020567550 A JP 2020567550A JP 2021526791 A JP2021526791 A JP 2021526791A
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nucleic acid
allele
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alleles
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アリエル ジャイモビッチ，
アンドリュー ケネディ，
ジャスティン アイ． オーデガード，
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ガーダント ヘルス， インコーポレイテッド
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Priority to JP2025185468A priority patent/JP2026012397A/ja
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    • G—PHYSICS
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
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    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
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    • G—PHYSICS
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    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

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  • Bioinformatics & Cheminformatics (AREA)
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JP2020567550A 2018-06-04 2019-06-03 セルフリー核酸の細胞起源を決定するための方法およびシステム Pending JP2021526791A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023199814A JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

Applications Claiming Priority (3)

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US201862680301P 2018-06-04 2018-06-04
US62/680,301 2018-06-04
PCT/US2019/035214 WO2019236478A1 (en) 2018-06-04 2019-06-03 Methods and systems for determining the cellular origin of cell-free nucleic acids

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JP2021526791A true JP2021526791A (ja) 2021-10-11
JP2021526791A5 JP2021526791A5 (https=) 2022-06-10

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JP2020567550A Pending JP2021526791A (ja) 2018-06-04 2019-06-03 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2023199814A Withdrawn JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

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JP2023199814A Withdrawn JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

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US (1) US20190385700A1 (https=)
EP (1) EP3802878A1 (https=)
JP (3) JP2021526791A (https=)
WO (1) WO2019236478A1 (https=)

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US9940670B2 (en) * 2009-12-10 2018-04-10 Royal Bank Of Canada Synchronized processing of data by networked computing resources
EP3731959B1 (en) 2017-12-29 2025-10-08 Clear Labs, Inc. Automated priming and library loading device
ES2937927T3 (es) 2018-01-29 2023-04-03 St Jude Childrens Res Hospital Inc Método para la amplificación de ácidos nucleicos
WO2020023420A2 (en) 2018-07-23 2020-01-30 Guardant Health, Inc. Methods and systems for adjusting tumor mutational burden by tumor fraction and coverage
CN120412737A (zh) 2019-05-03 2025-08-01 阿尔缇玛基因组学公司 用于检测核酸变体的方法
US12437839B2 (en) 2019-05-03 2025-10-07 Ultima Genomics, Inc. Methods for detecting nucleic acid variants
US20230095295A1 (en) * 2020-02-10 2023-03-30 BioSkryb Genomics, Inc. Phi29 mutants and use thereof
EP4118653B1 (en) * 2020-03-11 2024-07-17 Guardant Health, Inc. Methods for classifying genetic mutations detected in cell-free nucleic acids as tumor or non-tumor origin
CA3173453A1 (en) * 2020-03-26 2021-09-30 Wai Yi Tsui Systems and methods for distinguishing pathological mutations from clonal hematopoietic mutations in plasma cell-free dna by fragment size analysis
TWI803855B (zh) * 2020-04-21 2023-06-01 美商西方數位科技公司 用於定序核酸之系統及裝置、定序複數個ｓ個核酸股之方法及減輕由於使用單分子感測器陣列之核酸定序程序而產生之定序資料之錯誤之方法
CN113257350B (zh) * 2021-06-10 2021-10-08 臻和(北京)生物科技有限公司 基于液体活检的ctDNA突变程度分析方法和装置、ctDNA性能分析装置

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US20190385700A1 (en) 2019-12-19
JP2026012397A (ja) 2026-01-23
JP2024015059A (ja) 2024-02-01
WO2019236478A1 (en) 2019-12-12
EP3802878A1 (en) 2021-04-14

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