JP2021512848A - Underwater oil type emulsified cosmetic - Google Patents
Underwater oil type emulsified cosmetic Download PDFInfo
- Publication number
- JP2021512848A JP2021512848A JP2019563858A JP2019563858A JP2021512848A JP 2021512848 A JP2021512848 A JP 2021512848A JP 2019563858 A JP2019563858 A JP 2019563858A JP 2019563858 A JP2019563858 A JP 2019563858A JP 2021512848 A JP2021512848 A JP 2021512848A
- Authority
- JP
- Japan
- Prior art keywords
- oil
- water emulsified
- emulsified cosmetic
- group
- hydrophobic group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 70
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 60
- 239000003921 oil Substances 0.000 claims abstract description 43
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 31
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 27
- 229920000642 polymer Polymers 0.000 claims abstract description 25
- 125000001165 hydrophobic group Chemical group 0.000 claims abstract description 21
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229920000058 polyacrylate Polymers 0.000 claims abstract description 14
- 150000004676 glycans Chemical class 0.000 claims abstract description 12
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 12
- 239000005017 polysaccharide Substances 0.000 claims abstract description 12
- 239000003945 anionic surfactant Substances 0.000 claims abstract description 8
- 239000012736 aqueous medium Substances 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 12
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 11
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 9
- 229920002545 silicone oil Polymers 0.000 claims description 8
- 238000004945 emulsification Methods 0.000 claims description 7
- 230000001804 emulsifying effect Effects 0.000 claims description 5
- 229920001451 polypropylene glycol Polymers 0.000 claims description 5
- 229920000570 polyether Polymers 0.000 claims description 4
- 229920002678 cellulose Polymers 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- 229920000233 poly(alkylene oxides) Polymers 0.000 claims description 2
- 230000005591 charge neutralization Effects 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 abstract description 4
- 238000010586 diagram Methods 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 description 41
- 230000000052 comparative effect Effects 0.000 description 19
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- 125000000217 alkyl group Chemical group 0.000 description 8
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- 239000007788 liquid Substances 0.000 description 7
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- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 6
- 125000004432 carbon atom Chemical group C* 0.000 description 6
- 229920001577 copolymer Polymers 0.000 description 6
- 238000002845 discoloration Methods 0.000 description 6
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical class NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 6
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 5
- 150000003839 salts Chemical class 0.000 description 5
- OBETXYAYXDNJHR-UHFFFAOYSA-N 2-Ethylhexanoic acid Chemical compound CCCCC(CC)C(O)=O OBETXYAYXDNJHR-UHFFFAOYSA-N 0.000 description 4
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 4
- 235000021355 Stearic acid Nutrition 0.000 description 4
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- 125000002768 hydroxyalkyl group Chemical group 0.000 description 4
- 239000012948 isocyanate Substances 0.000 description 4
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 4
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 230000001953 sensory effect Effects 0.000 description 4
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
- 239000008117 stearic acid Substances 0.000 description 4
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- 230000002123 temporal effect Effects 0.000 description 4
- 239000001993 wax Substances 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 3
- 125000001183 hydrocarbyl group Chemical group 0.000 description 3
- 238000002156 mixing Methods 0.000 description 3
- 239000002736 nonionic surfactant Substances 0.000 description 3
- 229920003169 water-soluble polymer Polymers 0.000 description 3
- ULQISTXYYBZJSJ-UHFFFAOYSA-N 12-hydroxyoctadecanoic acid Chemical compound CCCCCCC(O)CCCCCCCCCCC(O)=O ULQISTXYYBZJSJ-UHFFFAOYSA-N 0.000 description 2
- KIHBGTRZFAVZRV-UHFFFAOYSA-N 2-Hydroxyoctadecanoic acid Natural products CCCCCCCCCCCCCCCCC(O)C(O)=O KIHBGTRZFAVZRV-UHFFFAOYSA-N 0.000 description 2
- GTJOHISYCKPIMT-UHFFFAOYSA-N 2-methylundecane Chemical compound CCCCCCCCCC(C)C GTJOHISYCKPIMT-UHFFFAOYSA-N 0.000 description 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical class C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
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- SGVYKUFIHHTIFL-UHFFFAOYSA-N Isobutylhexyl Natural products CCCCCCCC(C)C SGVYKUFIHHTIFL-UHFFFAOYSA-N 0.000 description 2
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- 244000025272 Persea americana Species 0.000 description 2
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- 125000004453 alkoxycarbonyl group Chemical group 0.000 description 2
- 125000003368 amide group Chemical group 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 229940024606 amino acid Drugs 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 239000002280 amphoteric surfactant Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 229940121363 anti-inflammatory agent Drugs 0.000 description 2
- 239000008346 aqueous phase Substances 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- WSWYZRBSUBMICN-UHFFFAOYSA-N azanium;2-(dimethylamino)-3-oxopent-4-ene-1-sulfonate Chemical compound [NH4+].[O-]S(=O)(=O)CC(N(C)C)C(=O)C=C WSWYZRBSUBMICN-UHFFFAOYSA-N 0.000 description 2
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000004205 dimethyl polysiloxane Substances 0.000 description 2
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 2
- 239000003792 electrolyte Substances 0.000 description 2
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- 239000000194 fatty acid Substances 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- DCAYPVUWAIABOU-UHFFFAOYSA-N hexadecane Chemical compound CCCCCCCCCCCCCCCC DCAYPVUWAIABOU-UHFFFAOYSA-N 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- VKPSKYDESGTTFR-UHFFFAOYSA-N isododecane Natural products CC(C)(C)CC(C)CC(C)(C)C VKPSKYDESGTTFR-UHFFFAOYSA-N 0.000 description 2
- 229940071085 lauroyl glutamate Drugs 0.000 description 2
- 125000005647 linker group Chemical group 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
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- 239000003755 preservative agent Substances 0.000 description 2
- CXMXRPHRNRROMY-UHFFFAOYSA-N sebacic acid Chemical compound OC(=O)CCCCCCCCC(O)=O CXMXRPHRNRROMY-UHFFFAOYSA-N 0.000 description 2
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- 239000011734 sodium Substances 0.000 description 2
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- 125000001424 substituent group Chemical group 0.000 description 2
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- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
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- 239000004711 α-olefin Substances 0.000 description 2
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 description 1
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- UYTOHYBIBPDOKX-ZDUSSCGKSA-N (2s)-2-(dodecanoylamino)propanoic acid Chemical class CCCCCCCCCCCC(=O)N[C@@H](C)C(O)=O UYTOHYBIBPDOKX-ZDUSSCGKSA-N 0.000 description 1
- XDOBXTLSTUFRRP-HNNXBMFYSA-N (2s)-2-(tetradecanoylamino)propanoic acid Chemical class CCCCCCCCCCCCCC(=O)N[C@@H](C)C(O)=O XDOBXTLSTUFRRP-HNNXBMFYSA-N 0.000 description 1
- NNOIKAOFOKMZKU-UHFFFAOYSA-N (3-hexanoyloxy-2,2-dimethylpropyl) hexanoate Chemical compound CCCCCC(=O)OCC(C)(C)COC(=O)CCCCC NNOIKAOFOKMZKU-UHFFFAOYSA-N 0.000 description 1
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- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
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- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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- Dispersion Chemistry (AREA)
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Abstract
水性媒体、アニオン界面活性剤、油剤、疎水基変性親水性ウレタンポリマー、親水性基と疎水性基を含む側鎖を有する（メタ）アクリルポリマー、及び疎水基変性親水性多糖類からなる群より選ばれる両親媒性ポリマー、及び電荷中和剤を含有し、２５℃における粘度が１０，０００ｍＰａ・ｓ以上である、水中油型乳化化粧料。
【選択図】なしSelected from the group consisting of aqueous media, anionic surfactants, oils, hydrophobic group-modified hydrophilic urethane polymers, (meth) acrylic polymers having side chains containing hydrophilic groups and hydrophobic groups, and hydrophobic group-modified hydrophilic polysaccharides. An oil-in-water emulsified cosmetic containing an amphipathic polymer and a charge neutralizing agent and having a viscosity at 25 ° C. of 10,000 mPa · s or more.
[Selection diagram] None
Description
本発明は、水中油型乳化化粧料に関する。 The present invention relates to an oil-in-water emulsified cosmetic.
化粧品に用いられる製剤の一つである水中油型乳化物は、製剤中における適当量の油剤によって高いナリシング効果および保護効果を示し、特に高い粘性を有するそのような製剤は化粧クリームやエッセンスといった一般的なスキンケア製剤によく用いられる。 Oil-in-water emulsion, which is one of the preparations used in cosmetics, shows a high nourishing effect and protective effect by an appropriate amount of oil in the preparation, and such preparations having particularly high viscosity are general such as cosmetic creams and essences. Often used in traditional skin care products.
微細に分散したエマルションは高圧で乳化された水中油型乳化化粧料であり、このようなエマルションは一般的に多量の油剤を安定的に配合することができると考えられている（特許文献１）。加えて、特定の成分の高圧乳化により、十分な透明性と長期安定性を備えるゲル状の水中油型乳化組成物が得られることが報告されている（特許文献２）。 The finely dispersed emulsion is an oil-in-water emulsified cosmetic that is emulsified at high pressure, and it is generally considered that such an emulsion can stably blend a large amount of an oil agent (Patent Document 1). .. In addition, it has been reported that a gel-like oil-in-water emulsified composition having sufficient transparency and long-term stability can be obtained by high-pressure emulsification of a specific component (Patent Document 2).
特許文献１に記載された水中油型乳化化粧料では、含まれる添加剤によってはその安定性を維持できないため、実用に適しにくく、一方、特許文献２のゲル状の水中油型乳化組成物は、べたつく傾向にあり、化粧料として望ましくない感触を示す。 The oil-in-water emulsified cosmetic described in Patent Document 1 is not suitable for practical use because its stability cannot be maintained depending on the additives contained therein. On the other hand, the gel-like oil-in-water emulsified composition of Patent Document 2 is , Tends to be sticky and shows an undesired feel as a cosmetic.
本発明の目的は、べたつきがなく優れた安定性を示しながら、多量の油剤を含むことができる水中油型乳化化粧料を提供することである。 An object of the present invention is to provide an oil-in-water emulsified cosmetic that can contain a large amount of oil while exhibiting excellent stability without stickiness.
本発明は、（Ａ）水性媒体、（Ｂ）アニオン界面活性剤、（Ｃ）油剤、（Ｄ）疎水基変性親水性ウレタンポリマー、親水性基と疎水性基を含む側鎖を有する（メタ）アクリルポリマー、及び疎水基変性親水性多糖類からなる群より選ばれる両親媒性ポリマー、及び（Ｅ）電荷中和剤を含有する水中油型乳化化粧料であり、２５℃における粘度が１０，０００ｍＰａ・ｓ以上という特徴を有する化粧料を提供する。「（Ａ）水性媒体」は、以下単に「成分（Ａ）」とも呼ばれ、他の成分も同様に呼ばれる。「（メタ）アクリル」という用語はアクリル又はメタクリルを指し、類似の骨格でも同様である。 The present invention has (A) an aqueous medium, (B) an anionic surfactant, (C) an oil agent, (D) a hydrophobic group-modified hydrophilic urethane polymer, and a side chain containing a hydrophilic group and a hydrophobic group (meth). An oil-in-water emulsified cosmetic containing an amphipathic polymer selected from the group consisting of an acrylic polymer and a hydrophobic group-modified hydrophilic polysaccharide, and (E) a charge neutralizing agent, and having a viscosity at 25 ° C. of 10,000 mPa. -Provide cosmetics having the characteristics of s or more. The "(A) aqueous medium" is also simply referred to as "component (A)" below, and other components are also referred to in the same manner. The term "(meth) acrylic" refers to acrylic or methacrylic, as well as similar skeletons.
本発明の水中油型乳化化粧料は、多量の油剤を含有させることが可能であり、油剤が多いにもかかわらず、べたつきがなく優れた安定性を示す。さらに、優れたナリシング効果と、みずみずしく軽い感触、肌への浸透感を含む優れたテクスチャーとを有する。これらの特性に加えて、十分な耐光性と、変色・褪色が少ないという特徴も有している。 The oil-in-water emulsified cosmetic of the present invention can contain a large amount of oil, and despite the large amount of oil, it is not sticky and exhibits excellent stability. Furthermore, it has an excellent nourishing effect, a fresh and light feel, and an excellent texture including a feeling of penetration into the skin. In addition to these characteristics, it also has sufficient light resistance and less discoloration and fading.
一般の水中油型乳化化粧料は、肌への浸透性が低く、重さやべたつきを感じやすい傾向にある。本発明者らは、これが生じる理由が、十分なナリシング効果を発揮するための、適切な量で製剤中に油剤を安定的に乳化することと分散することが、過剰量の界面活性剤や界面活性助剤、ワックス類及び増粘剤を必要とし、これらの成分が重い感触やべたつきをもたらすからであると見出した。結果として、べたつきのないみずみずしい感触でありながら、高浸透性によって高いナリシング効果も提供する化粧料製剤は、存在していなかった。 General oil-in-water emulsified cosmetics have low penetration into the skin and tend to feel heavy and sticky. The present inventors consider that the reason why this occurs is that the stable emulsification and dispersion of the oil agent in the formulation in an appropriate amount in order to exert a sufficient nourishing effect is an excessive amount of the surfactant or the interface. We have found that this is because it requires active aids, waxes and thickeners, and these components provide a heavy feel and stickiness. As a result, there has been no cosmetic preparation that provides a high nourishing effect due to its high permeability while having a non-greasy and fresh feel.
上述の特許文献に開示された微細なエマルションを得る方法を実施することにより、ゲル状の外観を呈する水中油型乳化物を得ることができるが、これは、均一なサイズと、それらの間に電荷反発を有する粒子が、表面上近距離に位置し、そしてそれらの互いの電荷反発により、規則的な結晶様構造が形成されるためと考えられる。この乳化物においては、重さやべたつきを生じさせる因子を含有せずに、ナリシング効果を有する油剤を多量に添加できるが、電荷中和剤のような、一般的に使用される様々な添加剤が化粧料に添加された場合、微細なエマルションを含有するそのようなゲルは時間とともに不安定になる傾向にあり、徐々に粘度が減少していき、合一が引き起こされる可能性がある。 By carrying out the method for obtaining the fine emulsions disclosed in the above-mentioned patent documents, oil-in-water emulsions having a gel-like appearance can be obtained, which are of uniform size and between them. It is considered that the particles having charge repulsion are located at a short distance on the surface, and their mutual charge repulsion forms a regular crystal-like structure. In this emulsion, a large amount of oil having a nourishing effect can be added without containing factors that cause weight and stickiness, but various commonly used additives such as charge neutralizers can be added. When added to cosmetics, such gels containing fine emulsions tend to become unstable over time and gradually decrease in viscosity, which can lead to coalescence.
微細なエマルションで構成されるゲルが形成される原理を考えると、この現象の理由は、内的あるいは外的環境の影響が、結晶様構造を担うエマルション粒子間の電荷反発力の経時的な脆弱を引き起こし、結果として合一がもたらされると考えられる。 Considering the principle of forming a gel composed of fine emulsions, the reason for this phenomenon is that the influence of the internal or external environment causes the time-dependent weakness of the charge repulsive force between the emulsion particles that carry the crystal-like structure. Is thought to result in union.
特許文献１及び２は、この問題点の解決策を扱っておらず、特許文献１の場合、化粧料に一般的に用いられる種々の添加剤を添加した場合、安定性は不十分になる場合がある。特許文献２の場合では、べたつきが生じるおそれがある。このべたつきは、化粧料を安定させるために多量の界面活性剤の添加の必要性に起因するものであると考えられる。 Patent Documents 1 and 2 do not deal with a solution to this problem, and in the case of Patent Document 1, when various additives generally used for cosmetics are added, the stability becomes insufficient. There is. In the case of Patent Document 2, stickiness may occur. This stickiness is considered to be due to the need to add a large amount of surfactant to stabilize the cosmetic.
これらの化粧料とは対照的に、本発明の水中油型乳化化粧料は、べたつきのない軽い感触を有し、高浸透性によって高いナリシング効果を与え、経時安定性に優れた化粧料である。これらの効果は、成分（Ａ）から（Ｅ）の組み合わせによりもたらされるが、特に成分（Ｄ）は、エマルション粒子とそれ自身の疎水基との相互作用により製剤の粘度を高め、ゲルの形成に有効に寄与し、調製直後と、例えば５０℃に１か月静置した後の粘度において、経時での粘度が劇的に維持されている。 In contrast to these cosmetics, the oil-in-water emulsified cosmetic of the present invention is a cosmetic that has a light feel without stickiness, gives a high nourishing effect due to its high permeability, and is excellent in stability over time. .. These effects are brought about by the combination of the components (A) to (E), and in particular, the component (D) increases the viscosity of the preparation by the interaction between the emulsion particles and its own hydrophobic group, and is used for gel formation. It contributes effectively, and the viscosity with time is dramatically maintained immediately after the preparation and in the viscosity immediately after standing at 50 ° C. for one month, for example.
成分（Ｄ）以外の水溶性ポリマー、例えば、キサンタンガムや、カルボマー又はアルキルコポリマーといったアニオン性ポリマー、ヒドロキシエチルセルロースのようなノニオン性ポリマーが用いられる場合は、エマルション粒子間の電荷反発が妨げられ、結果として、粘度が低下して安定なゲル状水中油型乳化化粧料を得ることができない。 When water-soluble polymers other than component (D), such as xanthan gum, anionic polymers such as carbomer or alkyl copolymers, and nonionic polymers such as hydroxyethyl cellulose, are used, charge repulsion between emulsion particles is hindered, resulting in impeded charge repulsion. , It is not possible to obtain a stable gel-like oil-in-water emulsified cosmetic with a decrease in viscosity.
微細化エマルションで構成されるゲルは電荷反発により粒子の安定性を保っていることから、成分（Ｅ）のような電解質を添加するとその安定性が損なわれることが想像される。しかし、本発明によれば、他の成分、特に（Ｄ）成分による協働相互作用により、粒子の安定性が損なわれることなく優れた経時安定性が得られる。さらに、ナリシング効果、みずみずしく軽い感触、肌への浸透感といった感触も向上する。 Since the gel composed of the finely divided emulsion maintains the stability of the particles due to charge repulsion, it is conceivable that the stability is impaired when an electrolyte such as the component (E) is added. However, according to the present invention, excellent temporal stability can be obtained without impairing the stability of the particles by the cooperative interaction of other components, particularly the component (D). In addition, the nourishing effect, the fresh and light feel, and the feeling of penetration into the skin are also improved.
両親媒性ポリマーは、側鎖及び／又は末端鎖に疎水基を有しうる。例えば、両親媒性ポリマーは、疎水基変性親水性ウレタンポリマー及び／又は疎水基変性親水性多糖類であってよく、この場合、好ましくは、疎水基変性親水性ウレタンポリマーは、ポリオキシアルキレン成分を含む疎水基変性ポリエーテルウレタンを含有し、疎水基変性親水性多糖類は、疎水基変性ヒドロキシアルキルアルキルセルロースを含有する。このような両親媒性ポリマーの使用は、ナリシング効果、みずみずしく軽い感触、べたつきのなさ、肌への浸透感、伸び広がりのよさ、が特に優れるようになり、耐光性、低変色の特徴も顕著に向上する。 The amphipathic polymer may have hydrophobic groups in the side and / or terminal chains. For example, the amphoteric polymer may be a hydrophobic group-modified hydrophilic urethane polymer and / or a hydrophobic group-modified hydrophilic polysaccharide, in which case the hydrophobic group-modified hydrophilic urethane polymer preferably contains a polyoxyalkylene component. The hydrophobic group-modified hydrophilic polysaccharide contains a hydrophobic group-modified polyether urethane, and the hydrophobic group-modified hydrophilic polysaccharide contains a hydrophobic group-modified hydroxyalkylalkyl cellulose. The use of such amphipathic polymers has made them particularly excellent in nourishing effect, fresh and light feel, non-stickiness, penetration into the skin, and good spreadability, and features of light resistance and low discoloration are also remarkable. improves.
本発明の水中油型乳化化粧料は、水中油型乳化化粧料の全質量基準で２０質量％以上の含有比率である油剤を含有することができる。このような大量の油剤を配合することにより、ナリシング効果が顕著に向上する。 The oil-in-water emulsified cosmetic of the present invention can contain an oil having a content ratio of 20% by mass or more based on the total mass of the oil-in-water emulsified cosmetic. By blending such a large amount of oil agent, the nourishing effect is remarkably improved.
また、油剤としては、本発明の水中油型乳化化粧料は、液状油剤を含有することができる。液状油剤は、好ましくは、非極性油剤、シリコーン油剤、又はそれらの混合物である。このような油剤を使用することで、乳化化粧料の安定性が向上する。 Further, as the oil agent, the oil-in-water emulsified cosmetic of the present invention may contain a liquid oil agent. The liquid oil is preferably a non-polar oil, a silicone oil, or a mixture thereof. By using such an oil agent, the stability of the emulsified cosmetic is improved.
本発明の水中油型乳化化粧料は、１００ＭＰａ以上の圧力で乳化することにより得ることができる。油剤の配合量が多い場合であっても、このような乳化により、乳化安定性に優れ、べたつきが低減され、ナリシング効果、みずみずしく軽い感触、肌への浸透感等の感触が大変優れた水中油型乳化化粧料を容易に得ることが可能になる。なお、通常の分散工程により得られる水中油型乳化化粧料は、通常、調製後に即座に分離する。 The oil-in-water emulsified cosmetic of the present invention can be obtained by emulsifying at a pressure of 100 MPa or more. Even when the amount of oil is large, such emulsification provides excellent emulsification stability, reduces stickiness, and has excellent feelings such as nourishing effect, fresh and light feel, and penetration into the skin. It becomes possible to easily obtain a mold emulsified cosmetic. The oil-in-water emulsified cosmetic obtained by a usual dispersion step is usually separated immediately after preparation.
本発明は、べたつきがなく優れた安定性を示しながら、多量の油剤を含有させることができる水中油型乳化化粧料を提供することができる。 The present invention can provide an oil-in-water emulsified cosmetic that can contain a large amount of oil while exhibiting excellent stability without stickiness.
本実施形態に係る水中油型乳化化粧料における成分（Ａ）は水性媒体であり、少なくとも水を含有し、成分（Ｂ）から（Ｅ）の媒体となるものである。成分（Ａ）は水のみからなっていてよく、成分（Ｂ）、（Ｄ）及び（Ｅ）以外の水溶性成分を含んでもよい。 The component (A) in the oil-in-water emulsified cosmetic according to the present embodiment is an aqueous medium, contains at least water, and serves as a medium for the components (B) to (E). The component (A) may consist only of water, and may contain water-soluble components other than the components (B), (D) and (E).
水溶性成分には、ポリオール、モノオール、多糖類、ノニオン界面活性剤、両性界面活性剤、防腐剤、合成系水溶性ポリマー、紫外線吸収剤、紫外線遮蔽剤等が含まれる。水溶性成分には、抗菌剤、抗炎症剤、ビタミン及びアミノ酸も含まれる。 Water-soluble components include polyols, monools, polysaccharides, nonionic surfactants, amphoteric surfactants, preservatives, synthetic water-soluble polymers, ultraviolet absorbers, ultraviolet shielding agents and the like. Water-soluble components also include antibacterial agents, anti-inflammatory agents, vitamins and amino acids.
ポリオールの例には、ブチレングリコール、ペンチレングリコール、及びグリセリンが含まれる。多糖類には、ローカストビーンガム、グアーガム、フェヌグリークガム等のガラクトマンナン；カラギーナン、ガラクタン、アラビアガム、ペクチン、マンナン、デンプン等の植物系多糖類；キサンタンガム、デキストラン、スクシノグルカン、カードラン、ジェランガム等の微生物系多糖類等が含まれる。 Examples of polyols include butylene glycol, pentylene glycol, and glycerin. Polysaccharides include galactomannans such as locust bean gum, guar gum, and phenuglique gum; plant-based polysaccharides such as carrageenan, galactan, arabic gum, pectin, mannan, and starch; xanthan gum, dextran, succinoglucan, curdran, gellan gum, etc. Includes microbial polysaccharides and the like.
ノニオン界面活性剤としては、ポリソルベート２０、ポリソルベート６０、ポリソルベート６５、ポリソルベート８０のようなソルビタン脂肪酸エステルのエチレンオキシド付加物；オレス−２、セテス−６、ラウレス−４のようなアルキルエーテルのエチレンオキシド付加物を用いることができる。水添レシチンは、両性界面活性剤の例である。 Nonionic surfactants include ethylene oxide adducts of sorbitan fatty acid esters such as polysorbate 20, polysorbate 60, polysorbate 65, polysorbate 80; ethylene oxide adducts of alkyl ethers such as oleth-2, ceteth-6, laures-4. Can be used. Hydrogenated lecithin is an example of an amphoteric surfactant.
フェノキシエタノールは防腐剤の例であり、エタノールはモノオールの例である。 Phenoxyethanol is an example of preservatives and ethanol is an example of monool.
実施形態に係る水中油型乳化化粧料における成分（Ｂ）は、アニオン界面活性剤である。 The component (B) in the oil-in-water emulsified cosmetic according to the embodiment is an anionic surfactant.
アニオン界面活性剤には、ラウリン酸塩、パルミチン酸塩等の脂肪酸セッケン；セチルリン酸塩等のリン酸エステル塩；Ｎ−ラウロイルグルタミン酸塩、Ｎ−ミリストイル−Ｌ−グルタミン酸塩等のＮ−アシルグルタミン酸塩；Ｎ−ラウロイルグルタミン酸塩、Ｎ−ミリストイルグルタミン酸塩、Ｎ−ステアロイルグルタミン酸塩等のＮ−アシルグルタミン酸塩；Ｎ−ラウロイルグリシン塩、Ｎ−ミリストイルグリシン塩、Ｎ−ステアロイルグリシン塩等のＮ−アシルグリシン塩；Ｎ−ラウロイルアラニン塩、Ｎ−ミリストイルアラニン塩、Ｎ−ステアロイルアラニン塩等のＮ−アシルアラニン塩；Ｎ−ラウロイルアスパラギン酸塩、Ｎ−ミリストイルアスパラギン酸塩、Ｎ−ステアロイルアスパラギン酸塩等のＮ−アシルアスパラギン酸塩；Ｎ−ココイル−Ｎ−メチルタウリン塩、Ｎ−ラウロイル−Ｎ−メチルタウリン塩、Ｎ−ミリストイル−Ｎ−メチルタウリン塩、Ｎ−ステアロイル−Ｎ−メチルタウリン塩、Ｎ−ココイルタウリン塩等の長鎖アシル低級アルキル型タウリン塩；ジラウロイルグルタミン酸リシンＮａ、サーファクチンナトリウム等が挙げられる。なかでも、Ｎ−ステアロイルグルタミン酸ナトリウム等のＮ−アシルグルタミン酸塩が含まれる。 Anionic surfactants include fatty acid salts such as laurate and palmitate; phosphate salts such as cetyl phosphate; N-acylglutamate such as N-lauroyl glutamate and N-myristoyl-L-glutamate. N-acylglutamate such as N-lauroyl glutamate, N-myristoyl glutamate, N-stearoyl glutamate; N-acylglycine salt such as N-lauroyl glycine salt, N-myristoyl glycine salt, N-stearoyl glycine salt N-acylalanine salts such as N-lauroylalanine salt, N-myristoylalanine salt, N-stearoylalanine salt; Acylaspartate; N-cocoyl-N-methyltaurine salt, N-lauroyl-N-methyltaurine salt, N-myristoyl-N-methyltaurine salt, N-stearoyl-N-methyltaurine salt, N-cocoyltaurine salt Such as long-chain acyl lower alkyl type taurine salt; lysine Na dilauroyl glutamic acid, sodium surfactin and the like can be mentioned. Among them, N-acylglutamates such as sodium N-stearoyl glutamate are included.
本実施形態に係る水中油型乳化化粧料における成分（Ｃ）は、油剤である。添加される油剤は、好ましくは液状油剤である。油剤には、極性油剤、非極性油剤、シリコーン油剤が含まれる。 The component (C) in the oil-in-water emulsified cosmetic according to the present embodiment is an oil agent. The oil agent to be added is preferably a liquid oil agent. The oil agent includes a polar oil agent, a non-polar oil agent, and a silicone oil agent.
油剤には、イソノナン酸イソノニル、イソノナン酸イソトリデシル、パルミチン酸エチルヘキシル、エチルヘキサン酸セチル、ジエチルヘキサン酸ネオペンチルグリコール、ジカプリン酸ネオペンチルグリコール、トリエチルヘキサノイン、トリ（カプリル酸／カプリン酸）グリセリル、トリイソステアリン、トリイソステアリン酸トリメチロールプロパン、テトラエチルヘキサン酸ペンタエリスリチル、テトライソステアリン酸ペンタエリスリチル、テトライソステアリン酸ポリグリセル−２、ジ（カプリル酸／カプリン酸）プロパンジオール、ジイソステアリン酸プロパンジオール、オクタカプリル酸ポリグリセリル−６が含まれる。 Oils include isononyl isononanoate, isotridecyl isononanoate, ethylhexyl palmitate, cetyl ethylhexanoate, neopentyl glycol diethylhexanoate, neopentyl glycol dicaproate, triethylhexanoin, tri (caprylic acid / capric acid) glyceryl, triisostearate. , Trimethylol propane triisostearate, pentaerythricyl tetraethylhexanoate, pentaerythrityl tetraisostearate, polyglyceryl-2 tetraisostearate, di (caprylic acid / capric acid) propanediol, propanediol diisostearate, polyglyceryl octacaprylate- 6 is included.
さらに、油剤には、乳酸オクチルドデシル、リンゴ酸ジイソステアリル、イソステアリン酸ポリグリセリル−２、ジイソステアリン酸ポリグリセリル−２、トリイソステアリン酸ポリグリセリル−２、（イソステアリン酸／セバシン酸）ジトリメチロールプロパンオリゴエステル、トリエチルヘキサン酸エリスリチル、トリポリヒドロキシステアリン酸ジペンタエリスリチル、イソステアリン酸トレハロースエステルズ、ペンタイソステアリン酸ジペンタエリスリチル、ヒドロキシステアリン酸エチルヘキシル、ポリヒドロキシステアリン酸、流動パラフィン、スクワラン、α−オレフィンオリゴマー、ワセリン、ポリイソブチレン、ポリブテン、イソドデカン、イソヘキサデカン、重質流動イソパラフィンが含まれる。 Further, the oils include octyldodecyl lactate, diisostearyl malate, polyglyceryl-2 isostearate, polyglyceryl-2 diisostearate, polyglyceryl-2 triisostearate, ditrimethylolpropane oligoester (isostearic acid / sebacic acid), and triethylhexane. Erythrityl acid, dipentaerythrityl tripolyhydroxystearate, trehalose isostearates, dipentaerythrityl pentaisostearate, ethylhexyl hydroxystearate, polyhydroxystearic acid, liquid paraffin, squalane, α-olefin oligomer, vaseline, polyisobutylene, polybutene, isododecane, iso Includes hexadecane, heavy liquid isoparaffin.
シリコーン油剤もまた油剤として用いられてよい。シリコーン油剤の例には、ジメチルポリシロキサン、メチルフェニルポリシロキサン、デカメチルシクロペンタシロキサン、オクタメチルシクロテトラシロキサン、トリメチルシロキシケイ酸、高重合度メチルフェニルポリシロキサンが含まれる。 Silicone oils may also be used as oils. Examples of silicone oils include dimethylpolysiloxane, methylphenylpolysiloxane, decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, trimethylsiloxysilicate, and highly polymerizable methylphenylpolysiloxane.
これらの油剤のうち、１以上の液状非極性油剤及び液状シリコーン油剤を配合することが好ましい。好適な液状非極性油剤には、スクワラン、イソドデカン及びα−オレフィンオリゴマーが含まれ、好適な液状シリコーン油剤としては、ジメチルポリシロキサン及びデカメチルシクロペンタシロキサンが挙げられる。 Of these oils, it is preferable to mix one or more liquid non-polar oils and liquid silicone oils. Suitable liquid non-polar oils include squalane, isododecane and α-olefin oligomers, and suitable liquid silicone oils include dimethylpolysiloxane and decamethylcyclopentasiloxane.
これらに加えて使用し得る他の油剤には、ヒドロキシステアリン酸コレステリル、ヒドロキシステアリン酸フィトステリル、オレイン酸フィトステリル、ヘキサ（ヒドロキシステアリン酸／ステアリン酸／ロジン酸）ジペンタエリスリチル、テトラ（ヒドロキシステアリン酸／イソステアリン酸）ジペンタエリスリチル、ヘキサヒドロキシステアリン酸ジペンタエリスリチル、（エチルヘキサン酸／ステアリン酸／アジピン酸）グリセリル、トリ（カプリル酸／カプリン酸／ミリスチン酸／ステアリン酸）グリセリル、水添パーム油、ワセリン、ヘキサ（ベヘン酸／安息香酸／エチルヘキサン酸）ジペンタエリスリチル、ペースト状の植物油（野菜油、Vegetable oil）、シア脂（Butyrospermum Parkii）、マンゴー種子脂（Mangifera Indica）、アボカド脂（Persea Gratissima）等のペースト状油剤が含まれる。乳化化粧料中のペースト状油剤の量及びワックス類の量は、製品にべたつきを与えないために制限されることが好ましい。本発明の一実施形態によれば、乳化化粧料は１％未満のワックス類を含有し、好ましくはワックス類を含まない。 Other oils that may be used in addition to these include cholesteryl hydroxystearate, phytosteryl hydroxystearate, phytosteryl oleate, hexa (hydroxystearic acid / stearic acid / logonic acid) dipentaerythrityl, tetra (hydroxystearic acid / isostearic acid). Dipentaerythrityl, dipentaerythrityl hexahydroxystearate, (ethylhexanoic acid / stearic acid / adipic acid) glyceryl, tri (capric acid / capric acid / myristic acid / stearic acid) glyceryl, hydrogenated palm oil, vaseline, hexa (bechenic acid / benzoic acid) Acid / ethylhexanoic acid) Dipentaerythrityl, paste-like vegetable oil (vegetable oil), stearic acid (Butyrospermum Parkii), mango seed fat (Mangifera Indica), avocado fat (Persea Gratissima) and other paste-like oils are included. It is preferable that the amount of the paste-like oil and the amount of waxes in the emulsified cosmetic are limited so as not to give the product stickiness. According to one embodiment of the present invention, the emulsified cosmetic contains less than 1% of waxes, preferably does not contain waxes.
実施形態に係る水中油型乳化化粧料における成分（Ｄ）は、両親媒性ポリマーであり、疎水基変性親水性ウレタンポリマー、親水性基と疎水性基を含む側鎖を有する（メタ）アクリルポリマー及び疎水基変性親水性多糖類からなる群より選ばれる。 The component (D) in the oil-in-water emulsified cosmetic according to the embodiment is an amphipathic polymer, a hydrophobic group-modified hydrophilic urethane polymer, and a (meth) acrylic polymer having a side chain containing a hydrophilic group and a hydrophobic group. And selected from the group consisting of hydrophobic group-modified hydrophilic polymers.
上記両親媒性ポリマーにおいて、疎水基とは、疎水性を有する基であり、疎水基変性とは、分子への疎水基の付加である。 In the amphipathic polymer, the hydrophobic group is a group having hydrophobicity, and the hydrophobic group modification is the addition of a hydrophobic group to the molecule.
疎水基は、Ｃ１〜３０の炭化水素基であってよく、典型的にはＣ１〜３０の直鎖状又は分岐状のアルキル基である。炭素原子の数は、好ましくは６〜３０であり、より好ましくは１２〜２４である。 The hydrophobic group may be a C1-30 hydrocarbon group, typically a C1-30 linear or branched alkyl group. The number of carbon atoms is preferably 6 to 30, more preferably 12 to 24.
直鎖状又は分岐状のアルキル基は、ドデシル基（ラウリル基）、トリデシル基、テトラデシル基、ペンタデシル基、ヘキサデシル基、ヘプタデシル基、オクタデシル基、ノナデシル基、イコシル基、ドコシル基（ベヘニル基）、デシルテトラデシル基であり得る。 Linear or branched alkyl groups include dodecyl group (lauryl group), tridecylic group, tetradecyl group, pentadecyl group, hexadecyl group, heptadecyl group, octadecyl group, nonadecil group, icosyl group, docosyl group (behenyl group), decyl. It can be a tetradecyl group.
（疎水性基変性）親水性ウレタンポリマーには、（疎水性基変性）ポリエーテルウレタンが含まれ、前記ポリエーテルウレタンは、ポリエチレンオキシド及びポリプロピレンオキシドのようなポリアルキレンオキシド成分を含む。このような有用なウレタンポリマーは、ＰＥＯブロック、ＰＥＯ／ＰＰＯブロック、ＰＥＯ／ＰＰＯ／ＰＥＯブロック、ＰＰＯ／ＰＥＯ／ＰＰＯブロック等を有する親水性ウレタンポリマーの末端又は側鎖に、上述した疎水基が導入されたものが含まれる。ＰＥＯはポリエチレンオキシドを、ＰＰＯはポリプロピレンオキシドを表し、これらは、それぞれ、ＰＥＧ（ポリエチレングリコール）及びＰＰＧ（ポリプロピレングリコール）として記載されることがある。ウレタンを形成するイソシアネートは、芳香族イソシアネート、脂肪族イソシアネート又は脂環式イソシアネートであってよい。 The (hydrophobic group-modified) hydrophilic urethane polymer contains a (hydrophobic group-modified) polyether urethane, and the polyether urethane contains a polyalkylene oxide component such as polyethylene oxide and polypropylene oxide. In such a useful urethane polymer, the above-mentioned hydrophobic group is introduced into the terminal or side chain of the hydrophilic urethane polymer having PEO block, PEO / PPO block, PEO / PPO / PEO block, PPO / PEO / PPO block and the like. Includes what has been done. PEO stands for polyethylene oxide and PPO stands for polypropylene oxide, which may be described as PEG (polyethylene glycol) and PPG (polypropylene glycol), respectively. The isocyanate forming the urethane may be an aromatic isocyanate, an aliphatic isocyanate or an alicyclic isocyanate.
疎水基変性親水性ウレタンポリマーには、（ＰＥＧ−２４０／デシルテトラデセス−２０／ＨＤＩ）コポリマー(商品名：ADEKA NOLTM GT-700）、ＰＰＧ−１２／メチレンジフェニルジイソシアネート）コポリマー（商品名：EXPERTGELTM EG412）が含まれる。 Hydrophobic modified hydrophilic urethane polymers include (PEG-240 / decyltetradeceth-20 / HDI) copolymer (trade name: ADEKA NOL TM GT-700), PPG-12 / methylenediphenyl diisocyanate) copolymer (trade name:). EXPERTGEL TM EG412) is included.
親水性基と疎水性基を含む側鎖を有する有用な（メタ）アクリルポリマーは、カルボキシ基のような親水基を有する（メタ）アクリルポリマーであって、親水性基と疎水性基を含む側鎖を有するものである。 A useful (meth) acrylic polymer having a side chain containing a hydrophilic group and a hydrophobic group is a (meth) acrylic polymer having a hydrophilic group such as a carboxy group, the side containing the hydrophilic group and the hydrophobic group. It has a chain.
このようなポリマーには、カルボキシ基と、疎水性ブロックと親水性ブロックとから構成され、該親水性ブロック側で主鎖と結合した両親媒性側鎖とを有する（メタ）アクリルポリマーが含まれる。 Such a polymer includes a (meth) acrylic polymer composed of a carboxy group, a hydrophobic block and a hydrophilic block, and having an amphipathic side chain bonded to the main chain on the hydrophilic block side. ..
疎水性ブロックは、１を超す炭素原子の長さを有し、それ自体が疎水性であり、典型的には炭化水素骨格である。疎水性ブロックは、好ましくは炭素数１２〜２４の炭化水素骨格である。 Hydrophobic blocks have a length of more than 1 carbon atom and are hydrophobic in their own right, typically a hydrocarbon skeleton. The hydrophobic block is preferably a hydrocarbon backbone having 12 to 24 carbon atoms.
親水性ブロックとは、１を超す炭素原子の長さを有し、それ自体が親水性であり、典型的にはポリオキシアルキレン骨格である。親水性ブロックは、好ましくはポリオキシエチレン骨格であり、１０〜３０のオキシエチレンの繰り返しを有する。すなわち、それは好ましくは−（ＣＨ２ＣＨ２Ｏ）ｎ−の骨格を有し、ここでｎは１０〜３０であり、ｎの値は好ましくは１２〜２５、より好ましくは２０〜２５である。親水性ブロックは、直接主鎖と結合してよく、又はリンカーを介して主鎖と結合できる。リンカーは、オキシカルボニル基（−ＣＯ−Ｏ−）であってよく、この−Ｏ−部分が好ましくはポリオキシアルキレン骨格の炭素原子と結合する。 A hydrophilic block has a length of more than 1 carbon atom and is hydrophilic in itself, typically a polyoxyalkylene skeleton. The hydrophilic block is preferably a polyoxyethylene skeleton and has 10 to 30 repetitions of oxyethylene. That is, it preferably has a − (CH 2 CH 2 O) n − skeleton, where n is 10 to 30, and the value of n is preferably 12 to 25, more preferably 20 to 25. The hydrophilic block may be attached directly to the main chain or can be attached to the main chain via a linker. The linker may be an oxycarbonyl group (-CO-O-), and this -O- moiety is preferably bonded to the carbon atom of the polyoxyalkylene backbone.
（メタ）アクリルポリマーは、アルコキシカルボニル基を有していてもよく、アルコキシカルボニル基中のアルキル基は、好ましくは、Ｃ１〜２４のアルキル基である。 The (meth) acrylic polymer may have an alkoxycarbonyl group, and the alkyl group in the alkoxycarbonyl group is preferably an alkyl group of C1 to 24.
特に好適なものは、（メタ）アクリル酸、（メタ）アクリル酸アルキルエステル及び（メタ）アクリル酸ポリオキシエチレンモノアルキルエーテルエステルを繰返し単位として有するポリマー［（メタ）アクリル酸／（メタ）アクリル酸アルキル／（メタ）アクリル酸ＰＯＥモノアルキルエーテルエステル共重合体］である。このような成分の例には、ダウ・ケミカル社製、アキュリン２２（AcylynTM22）、アキュリン２８（AcylynTM28）が含まれる。 Particularly suitable are polymers having (meth) acrylic acid, (meth) acrylic acid alkyl ester and (meth) acrylic acid polyoxyethylene monoalkyl ether ester as repeating units [(meth) acrylic acid / (meth) acrylic acid. Alkyl / (meth) acrylic acid POE monoalkyl ether ester copolymer]. Examples of such components include Dow Chemical, Inc., Acylyn TM 22 and Acylyn TM 28.
親水性基と疎水性基を含む側鎖を有する有用な（メタ）アクリルポリマーは、疎水性ブロックと親水性ブロックとから構成され、該親水性ブロック側で主鎖と結合した両親媒性側鎖と、置換又は無置換のアミド基と、を有する（メタ）アクリルポリマーである。なお、両親媒性側鎖は、親水性ブロックと疎水性ブロックを有し、そのため、親水性基と疎水性基を含む側鎖に相当する。疎水性ブロックと親水性ブロックは上記と同様であり、アミド基の水素原子は、アルキル置換タウリン基等のアルキル置換アミノアルキルスルホン酸基で置換されていてもよい。このような成分には、アクリロイルジメチルタウリンアンモニウムメタクリル酸ベヘネス−２５クロスポリマー（商品名：ARISTOFLEXTM HMB)が含まれる。 A useful (meth) acrylic polymer having a side chain containing a hydrophilic group and a hydrophobic group is composed of a hydrophobic block and a hydrophilic block, and is an amphoteric side chain bonded to the main chain on the hydrophilic block side. And a (meth) acrylic polymer having a substituted or unsubstituted amide group. The amphipathic side chain has a hydrophilic block and a hydrophobic block, and therefore corresponds to a side chain containing a hydrophilic group and a hydrophobic group. The hydrophobic block and the hydrophilic block are the same as described above, and the hydrogen atom of the amide group may be substituted with an alkyl-substituted aminoalkylsulfonic acid group such as an alkyl-substituted taurine group. Such components include acryloyldimethyltaurine ammonium methacrylate-behenes-25 crosspolymer (trade name: ARISTOFLEX TM HMB).
親水性基と疎水性基を含む側鎖を有する他の有用な（メタ）アクリルポリマーは、モノマー単位として、Ｎ−ビニルピロリドンと、親水性基と疎水性基を含む置換基で置換された（メタ）アクリルアミドと、を有する（メタ）アクリルポリマーである。置換基には、アルキル置換タウリン基等のアルキル置換アミノアルキルスルホン酸基が含まれる。アルキル置換タウリン基の例には、ジメチルタウリン基（−ＮＨ−Ｃ（ＣＨ３）２−ＣＨ２−ＳＯ３Ｈ）が含まれる。アルキル置換タウリン基は側鎖を構成しており、−ＳＯ３Ｈ（又はこの塩）が親水基、−ＮＨと−ＳＯ３Ｈ（又はこの塩）の間の部分が疎水基である。このような成分の一つは、（アクリロイルジメチルタウリンアンモニウム／ＶＰ）コポリマー（商品名：ARISTOFLEXTM AVC）である。 Other useful (meth) acrylic polymers with side chains containing hydrophilic and hydrophobic groups were replaced with N-vinylpyrrolidone as a monomer unit with substituents containing hydrophilic and hydrophobic groups ( It is a (meth) acrylic polymer having, with (meth) acrylamide. Substituents include alkyl-substituted aminoalkylsulfonic acid groups such as alkyl-substituted taurine groups. Examples of alkyl-substituted taurine groups include dimethyl taurine group (-NH-C (CH 3) 2 -CH 2 -SO 3 H) is. The alkyl-substituted taurine group constitutes a side chain, -SO 3 H (or this salt) is a hydrophilic group, and the portion between -NH and -SO 3 H (or this salt) is a hydrophobic group. One such component is a (acryloyldimethyltaurine ammonium / VP) copolymer (trade name: ARISTOFLEX TM AVC).
親水性基と疎水性基を含む側鎖を有する他の有用な（メタ）アクリルポリマーは、（メタ）アクリル酸と、ヒドロキシアルキル（メタ）アクリレートとをモノマー単位として有する（メタ）アクリルポリマーである。この場合において、ヒドロキシアルキル基は側鎖を構成し、ヒドロキシアルキル基中のヒドロキシ基が親水基、アルキル基が疎水基である。ヒドロキシアルキル部分のアルキル基の炭素数は３〜１２であってよい。このような成分の一つは、アクリレーツコポリマー（商品名：BALANCETM RCFTMg）である。 Another useful (meth) acrylic polymer having a side chain containing a hydrophilic group and a hydrophobic group is a (meth) acrylic polymer having (meth) acrylic acid and hydroxyalkyl (meth) acrylate as monomer units. .. In this case, the hydroxyalkyl group constitutes a side chain, and the hydroxy group in the hydroxyalkyl group is a hydrophilic group and the alkyl group is a hydrophobic group. The alkyl group of the hydroxyalkyl moiety may have 3 to 12 carbon atoms. One such component is Acrylate Copolymer (trade name: BALANCE TM RCF TM g).
有用な疎水基変性親水性多糖類は、上述した疎水基で変性されたヒドロキシアルキルアルキルセルロース（ヒドロキシプロピルメチルセルロース等）である。このような成分の一つは、疎水基がステアロイル基である、疎水化ヒドロキシプロピルメチルセルロース（商品名：SANGELOSETM 90L）である。 A useful hydrophobic group-modified hydrophilic polysaccharide is the above-mentioned hydrophobic group-modified hydroxyalkylalkyl cellulose (hydroxypropyl methylcellulose, etc.). One such component is hydrophobicized hydroxypropyl methylcellulose (trade name: SANGELOSE TM 90L), in which the hydrophobic group is a stearoyl group.
本実施形態に係る水中油型乳化化粧料における成分（Ｅ）は、電荷中和剤である。電荷中和剤は、クエン酸、リン酸ナトリウム、リン酸二ナトリウム、亜硫酸水素ナトリウムのような一般的なバッファーから選択できる。他のバッファー、抗酸化剤、ｐＨ調整剤、キレート剤、美白剤、植物エキス、抗菌剤、抗炎症剤、ビタミン、アミノ酸等であって水中で電離するものも、電荷中和剤として用いることができる。電荷中和剤は、当業者により電解質とも呼ばれ得る。 The component (E) in the oil-in-water emulsified cosmetic according to the present embodiment is a charge neutralizer. The charge neutralizer can be selected from common buffers such as citric acid, sodium phosphate, disodium phosphate, sodium bisulfite. Other buffers, antioxidants, pH regulators, chelating agents, whitening agents, plant extracts, antibacterial agents, anti-inflammatory agents, vitamins, amino acids, etc. that ionize in water can also be used as charge neutralizers. it can. Charge neutralizers may also be referred to by those skilled in the art as electrolytes.
２５℃における水中油型乳化化粧料の粘度は、好ましくは１０，０００ｍＰａ・ｓ以上である。２５℃における粘度は、より好ましくは５０，０００〜３００，０００ｍＰａ・ｓであり、好ましくはゲル状の外観を呈する。 The viscosity of the oil-in-water emulsified cosmetic at 25 ° C. is preferably 10,000 mPa · s or more. The viscosity at 25 ° C. is more preferably 50,000 to 300,000 mPa · s, and preferably has a gel-like appearance.
水中油型乳化化粧料は、１００ＭＰａ以上の圧力で乳化して得ることができ、圧力は好ましくは１５０ＭＰａ以上であり、より好ましくは２００ＭＰａ以上であり、好ましくは５００ＭＰａ以下である。 The oil-in-water emulsified cosmetic can be obtained by emulsifying at a pressure of 100 MPa or more, and the pressure is preferably 150 MPa or more, more preferably 200 MPa or more, and preferably 500 MPa or less.
乳化は、高圧ホモジナイザーを用いて実施できる。高圧ホモジナイザーは、ポンプにより流体に加圧し、流路に設けられた微細なスリットから噴出させることにより、乳化を行う装置をいう。 Emulsification can be performed using a high pressure homogenizer. A high-pressure homogenizer is a device that emulsifies a fluid by pressurizing the fluid with a pump and ejecting it from a fine slit provided in the flow path.
水中油型乳化化粧料は、例えば、成分（Ａ）〜（Ｅ）を混合し、高圧ホモジナイザーを用いて２００ＭＰａの圧力で乳化して得ることができる。
したがって、本発明は、上記の水中油型乳化化粧料の調製方法にも関する。この方法は、成分（Ａ）から（Ｅ）の混合物を、高圧ホモジナイザーにより、１００ＭＰａ以上、好ましくは１５０ＭＰａ以上、より好ましくは２００ＭＰａ以上、また、好ましくは５００ＭＰａ以下の圧力で乳化するステップを含む。圧力は２００ＭＰａとすることができる。
調製方法の第１のステップでは、第１の混合物を得るために、水性媒体（Ａ）、アニオン界面活性剤（Ｂ）及びポリマー（Ｃ）を温度Ｔで加熱し、混合し撹拌（例えば２５００ｒｐｍの速度で）すればよい。
第２のステップでは、第１のステップで得られた第１の混合物に油剤（Ｄ）及び電荷中和剤（Ｅ）をこの順で加え、第１のステップと同じ条件で撹拌された第２の混合物を得ることができる。第２のステップにおける成分の混合及び添加は、好ましくは温度Ｔに等しい温度で行われる。
第３のステップでは、第２の混合物を温度Ｔから室温まで冷却した後、高圧ホモジナイザー（例えば、モデルStar Burst：スギノマシン社の製品）で乳化して、水中油型乳化化粧料を得る。圧力は、好ましくは１００ＭＰａ以上、好ましくは１５０ＭＰａ以上、より好ましくは２００ＭＰａ以上で、好ましくは５００ＭＰａ以下である。圧力は２００ＭＰａとすることができる。
The oil-in-water emulsified cosmetic can be obtained, for example, by mixing the components (A) to (E) and emulsifying them with a high-pressure homogenizer at a pressure of 200 MPa.
Therefore, the present invention also relates to the above-mentioned method for preparing an oil-in-water emulsified cosmetic. This method comprises emulsifying a mixture of components (A) to (E) with a high pressure homogenizer at a pressure of 100 MPa or more, preferably 150 MPa or more, more preferably 200 MPa or more, and preferably 500 MPa or less. The pressure can be 200 MPa.
In the first step of the preparation method, the aqueous medium (A), the anionic surfactant (B) and the polymer (C) are heated at temperature T, mixed and stirred (eg at 2500 rpm) to obtain the first mixture. (At speed).
In the second step, the oil agent (D) and the charge neutralizing agent (E) were added to the first mixture obtained in the first step in this order, and the mixture was stirred under the same conditions as in the first step. Mixtures can be obtained. The mixing and addition of the components in the second step is preferably carried out at a temperature equal to temperature T.
In the third step, the second mixture is cooled from temperature T to room temperature and then emulsified with a high pressure homogenizer (eg, model Star Burst: product of Sugino Machine Limited) to obtain an oil-in-water emulsified cosmetic. The pressure is preferably 100 MPa or more, preferably 150 MPa or more, more preferably 200 MPa or more, and preferably 500 MPa or less. The pressure can be 200 MPa.
水中油型乳化化粧料において、成分（Ｃ）の含有比率は、好ましくは２０質量％以上であり、より好ましくは２０〜６０質量％である。好ましくは、成分（Ｂ）の含有比率は０．１〜１０質量％、成分（Ｄ）の含有比率は０．０１〜２質量％、成分（Ｅ）の含有比率は、０．００１〜５質量％である。成分（Ａ）は残分を構成する。成分（Ｃ）の含有比率の下限は、好ましくは３０質量％、より好ましくは４０質量％であり、下限は５０質量％であってもよい。成分（Ｃ）は、好ましくは（Ｃ１）非極性油剤及びシリコーン油剤からなる群より選ばれる少なくとも１種と、（Ｃ２）これ以外の油剤とを含み、油剤全体に対するＣ１成分の含有比率は、好ましくは５０〜９８質量％である。より好ましくは６０〜９８質量％であり、更に好ましくは７０〜９５質量％である。これらの比率は、水中油型乳化化粧料の全質量を基準とする。 In the oil-in-water emulsified cosmetic, the content ratio of the component (C) is preferably 20% by mass or more, more preferably 20 to 60% by mass. Preferably, the content ratio of the component (B) is 0.1 to 10% by mass, the content ratio of the component (D) is 0.01 to 2% by mass, and the content ratio of the component (E) is 0.001 to 5% by mass. %. Component (A) constitutes the balance. The lower limit of the content ratio of the component (C) is preferably 30% by mass, more preferably 40% by mass, and the lower limit may be 50% by mass. The component (C) preferably contains at least one selected from the group consisting of (C1) non-polar oil and silicone oil, and (C2) other oils, and the content ratio of the C1 component to the total oil is preferable. Is 50 to 98% by mass. It is more preferably 60 to 98% by mass, and even more preferably 70 to 95% by mass. These ratios are based on the total mass of oil-in-water emulsified cosmetics.
水中油型乳化化粧料は、高いナリシング効果、みずみずしい軽い感覚、べたつきのなさ、及び優れた安定性といった特性を発揮する。高いナリシング効果は、微細化エマルションに内包された適当量の油剤に起因し、みずみずしい軽い感触は、アニオン界面活性剤からなるエマルション粒子間の電荷反発によって形成される結晶様構造に起因する。べたつきのなさは、水溶性ポリマー、界面活性剤及び界面活性助剤の少ない配合量に起因し、安定性は、成分（Ｄ）による結晶様構造の保持に起因する。
本発明はまた、上述した水中油型乳化化粧料を肌に施用するステップを含むスキンケアの方法に関する。スキンケアは、肌のナリシングを含み、これは、みずみずしく軽い感触、べたつきのなさ及び／又は肌への浸透感とともに好適に得ることができる。特定の実施形態では、本発明は、上述した水中油型乳化化粧料を肌に施用するステップを含む、肌のナリシング方法に関する。
Oil-in-water emulsified cosmetics exhibit properties such as high nourishing effect, fresh and light sensation, non-stickiness, and excellent stability. The high nourishing effect is due to the appropriate amount of oil contained in the micronized emulsion, and the fresh and light feel is due to the crystal-like structure formed by charge repulsion between the emulsion particles made of the anionic surfactant. The non-stickiness is due to the small amount of the water-soluble polymer, surfactant and surfactant, and the stability is due to the retention of the crystal-like structure by the component (D).
The present invention also relates to a skin care method comprising applying the above-mentioned oil-in-water emulsified cosmetic to the skin. Skin care includes skin nourishing, which can be suitably obtained with a fresh and light feel, non-stickiness and / or a feeling of penetration into the skin. In certain embodiments, the present invention relates to a skin nourishing method comprising applying the above-mentioned oil-in-water emulsified cosmetic to the skin.
実施例により本発明を具体的に説明するが、本発明はこれらの実施例に限定されることを意味するものではない。 Although the present invention will be specifically described with reference to Examples, the present invention does not mean that the present invention is limited to these Examples.
＜実施例１〜９、比較例１〜５＞
表１に示す、含有するポリマーの種類及び含有量が異なる水中油型乳化化粧料は、以下の方法によりを調製された（実施例１〜９及び比較例１〜５）。まず、水性媒体（欄「ａ」）アニオン界面活性剤（欄「ｂ」）及びポリマー（欄「ｃ」）を加熱し、撹拌機を用いて２５００ｒｐｍで混合し撹拌した。次に、油剤（欄「ｄ」）、電荷中和剤（欄「ｅ」）をこの順で添加して、成分を同条件にて混合し撹拌して、混合物を得た。混合物を室温まで冷却した後、高圧ホモジナイザー（Ｓｔａｒ Ｂｕｒｓｔ：スギノマシン社製）を用いて、２００ＭＰａの圧力で処理し、水中油型乳化化粧料を得た。各原料の含有量（質量％）は、表１に示すとおりである。
<Examples 1 to 9, Comparative Examples 1 to 5>
The oil-in-water emulsified cosmetics shown in Table 1 having different types and contents of polymers were prepared by the following methods (Examples 1 to 9 and Comparative Examples 1 to 5). First, the aqueous medium (column "a"), the anionic surfactant (column "b") and the polymer (column "c") were heated, mixed and stirred at 2500 rpm using a stirrer. Next, an oil agent (column "d") and a charge neutralizer (column "e") were added in this order, and the components were mixed under the same conditions and stirred to obtain a mixture. After cooling the mixture to room temperature, it was treated with a high-pressure homogenizer (Star Burst: manufactured by Sugino Machine Limited) at a pressure of 200 MPa to obtain an oil-in-water emulsified cosmetic. The content (mass%) of each raw material is as shown in Table 1.
＜官能評価＞
実施例１〜９及び比較例１〜５の水中油型乳化化粧料は、ナリシング効果、みずみずしく軽い感触、べたつきのなさ、肌への浸透感を、本発明者らが所属する組織の化粧品専門評価パネルによる肌への単回使用試験において評価され、評価は以下の基準で行われた。結果を表１に示す。
（１）ナリシング効果、みずみずしく軽い感触、肌への浸透感
Ａ：強い
Ｂ：中程度
Ｃ：ほとんど感じない
Ｄ：感じない
（２）べたつきのなさ
Ａ：べたつきを全く感じない
Ｂ：べたつきをほとんど感じない
Ｃ：べたつきをわずかに感じる
Ｄ：べたつきを感じる
<Sensory evaluation>
The oil-in-water emulsified cosmetics of Examples 1 to 9 and Comparative Examples 1 to 5 have a nourishing effect, a fresh and light feel, no stickiness, and a feeling of penetration into the skin. It was evaluated in a single-use test on the skin using a panel, and the evaluation was performed according to the following criteria. The results are shown in Table 1.
(1) Nourishing effect, fresh and light feel, penetration into the skin A: Strong B: Medium C: Almost no feeling D: No feeling (2) No stickiness A: No stickiness B: Almost no stickiness No C: Slightly sticky D: Feels sticky
＜外観評価＞
実施例１〜９及び比較例１〜５の水中油型乳化化粧料について、変色の有無を評価した。調製した各水中油型乳化化粧料を透明容器に収容し、蓋で密閉して、自然光のもとで１か月保管した後に各水中油型乳化化粧料の変色の有無を評価した。評価は変色の少ない順にＡ〜Ｄの４段階で行われ、変色が全く認められなかったものをＡとした。結果を表１に示す。
<Appearance evaluation>
The presence or absence of discoloration was evaluated for the oil-in-water emulsified cosmetics of Examples 1 to 9 and Comparative Examples 1 to 5. Each of the prepared oil-in-water emulsified cosmetics was placed in a transparent container, sealed with a lid, stored in natural light for one month, and then the presence or absence of discoloration of each oil-in-water emulsified cosmetic was evaluated. The evaluation was carried out in four stages from A to D in ascending order of discoloration, and the one in which no discoloration was observed was designated as A. The results are shown in Table 1.
＜安定性の評価＞
実施例１〜９及び比較例１〜５の水中油型乳化化粧料について、経時安定性を評価した。各化粧料を透明容器に収容し、蓋で密閉して、５０℃で１か月保管した。保管後、油相と水相の分離を観察した。調製翌日および５０℃で１か月保管後に、回転粘度計（Ａｎｔｏｎ Ｐａａｒ ＧｍｂＨ製のＲｈｅｏｌａｂ ＱＣ）（回転数１０ｒｐｍ）を用いて、各化粧料のせん断粘度を２５℃で測定した。油相と水相の分離の程度と、調製翌日から５０℃での１か月保管までの粘度変化を観察し、初めの状態から変化の小さい順にＡ〜Ｄの４段階のスケールで評価した。結果を表１に示す。
<Evaluation of stability>
The oil-in-water emulsified cosmetics of Examples 1 to 9 and Comparative Examples 1 to 5 were evaluated for stability over time. Each cosmetic was placed in a transparent container, sealed with a lid, and stored at 50 ° C. for 1 month. After storage, the separation of the oil phase and the aqueous phase was observed. The day after preparation and after storage at 50 ° C. for 1 month, the shear viscosity of each cosmetic was measured at 25 ° C. using a rotational viscometer (Rheolab QC manufactured by Antonio Par GmbH) (rotation speed 10 rpm). The degree of separation between the oil phase and the aqueous phase and the change in viscosity from the day after preparation to storage at 50 ° C. for 1 month were observed, and evaluation was performed on a 4-step scale from A to D in ascending order of change from the initial state. The results are shown in Table 1.
＜実施例１０〜１２、比較例６＞
実施例１０〜１２及び比較例６について、表２に示す、電荷中和剤の種類及び含有量が異なる水中油型乳化化粧料を、実施例１〜９、比較例１〜５と同様の方法により調製した。各原料の含有量（質量％）は、表２に示すとおりである。
<Examples 10 to 12, Comparative Example 6>
For Examples 10 to 12 and Comparative Example 6, oil-in-water emulsified cosmetics having different types and contents of charge neutralizing agents shown in Table 2 were prepared in the same manner as in Examples 1 to 9 and Comparative Examples 1 to 5. Prepared by. The content (mass%) of each raw material is as shown in Table 2.
実施例１０〜１２及び比較例６の水中油型乳化化粧料について、実施例１〜９、比較例１〜５と同様の方法により、官能評価、外観評価、及び経時安定性の評価を行った。結果を表２に示す。 The oil-in-water emulsified cosmetics of Examples 10 to 12 and Comparative Example 6 were subjected to sensory evaluation, appearance evaluation, and temporal stability evaluation by the same methods as in Examples 1 to 9 and Comparative Examples 1 to 5. .. The results are shown in Table 2.
＜実施例１３〜１６、比較例７＞
実施例１３〜１６及び比較例７について、表３に示す、油剤及びノニオン界面活性剤の種類及び含有量が異なる水中油型乳化化粧料を、実施例１〜９、比較例１〜５と同様の方法により調製した。各原料の含有量（質量％）は、表３に示すとおりである。
<Examples 13 to 16, Comparative Example 7>
Regarding Examples 13 to 16 and Comparative Example 7, the oil-in-water emulsified cosmetics shown in Table 3 having different types and contents of the oil agent and the nonionic surfactant were used in the same manner as in Examples 1 to 9 and Comparative Examples 1 to 5. It was prepared by the method of. The content (mass%) of each raw material is as shown in Table 3.
実施例１３〜１６及び比較例７の水中油型乳化化粧料について、実施例１〜９、比較例１〜５と同様の方法により、官能評価、外観評価、及び経時安定性の評価を行った。結果を表３に示す。 The oil-in-water emulsified cosmetics of Examples 13 to 16 and Comparative Example 7 were subjected to sensory evaluation, appearance evaluation, and temporal stability evaluation by the same methods as in Examples 1 to 9 and Comparative Examples 1 to 5. .. The results are shown in Table 3.
＜実施例１７、比較例８＞
実施例１７について、表４に示す組成を有する水中油型乳化化粧料を、実施例１〜９、比較例１〜５と同様の方法により調製した。比較例８の水中油型乳化化粧料は、高圧ホモジナイザーによる高圧乳化を行わずに、攪拌機を用いて２５００ｒｐｍで１０分間撹拌しるのみにより得られた。各原料の含有量（質量％）は、表４に示すとおりである。
<Example 17, Comparative Example 8>
For Example 17, oil-in-water emulsified cosmetics having the compositions shown in Table 4 were prepared in the same manner as in Examples 1-9 and Comparative Examples 1-5. The oil-in-water emulsified cosmetic of Comparative Example 8 was obtained only by stirring at 2500 rpm for 10 minutes using a stirrer without performing high-pressure emulsification with a high-pressure homogenizer. The content (mass%) of each raw material is as shown in Table 4.
実施例１７及び比較例８の水中油型乳化化粧料について、実施例１〜９、比較例１〜５と同様の方法により、官能評価、外観評価、及び経時安定性の評価を行った。結果を表４に示す。 The oil-in-water emulsified cosmetics of Examples 17 and 8 were subjected to sensory evaluation, appearance evaluation, and temporal stability evaluation by the same methods as in Examples 1 to 9 and Comparative Examples 1 to 5. The results are shown in Table 4.
Claims (8)
アニオン界面活性剤、
油剤、
疎水基変性親水性ウレタンポリマー、親水性基と疎水性基を含む側鎖を有する（メタ）アクリルポリマー、及び疎水基変性親水性多糖類からなる群より選ばれる両親媒性ポリマー、及び
電荷中和剤を含有し、
２５℃における粘度が１０，０００ｍＰａ・ｓ以上である、水中油型乳化化粧料。 Aqueous medium and
Anionic surfactant,
Oil,
Hydrophobic group-modified hydrophilic urethane polymer, (meth) acrylic polymer having side chains containing hydrophilic group and hydrophobic group, and amphoteric polymer selected from the group consisting of hydrophobic group-modified hydrophilic polysaccharide, and charge neutralization. Contains the agent,
An oil-in-water emulsified cosmetic having a viscosity of 10,000 mPa · s or more at 25 ° C.
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- 2017-12-22 WO PCT/EP2017/084551 patent/WO2019120590A1/en unknown
- 2017-12-22 CN CN201780091329.5A patent/CN110678161A/en active Pending
- 2017-12-22 US US16/612,626 patent/US11298301B2/en active Active
- 2017-12-22 KR KR1020197034508A patent/KR102584095B1/en active IP Right Grant
- 2017-12-22 ES ES17823163T patent/ES2909189T3/en active Active
- 2017-12-22 JP JP2019563858A patent/JP7211666B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| JP7211666B2 (en) | 2023-01-24 |
| KR20200102338A (en) | 2020-08-31 |
| KR102584095B1 (en) | 2023-10-04 |
| EP3727279A1 (en) | 2020-10-28 |
| ES2909189T3 (en) | 2022-05-05 |
| US11298301B2 (en) | 2022-04-12 |
| CN110678161A (en) | 2020-01-10 |
| EP3727279B1 (en) | 2022-01-26 |
| WO2019120590A1 (en) | 2019-06-27 |
| US20200197264A1 (en) | 2020-06-25 |
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