JP2021505200A - ゲノムインプリンティングの障害を治療するための組成物及び方法 - Google Patents

ゲノムインプリンティングの障害を治療するための組成物及び方法 Download PDF

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JP2021505200A
JP2021505200A JP2020550047A JP2020550047A JP2021505200A JP 2021505200 A JP2021505200 A JP 2021505200A JP 2020550047 A JP2020550047 A JP 2020550047A JP 2020550047 A JP2020550047 A JP 2020550047A JP 2021505200 A JP2021505200 A JP 2021505200A
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seq
znf274
binding site
pws
dna targeting
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JP2021505200A5 (enExample
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ストーミー チェンバレン
ストーミー チェンバレン
ジャスティン コットニー
ジャスティン コットニー
マエヴァ ラングエ
マエヴァ ラングエ
マーク ラランド
マーク ラランド
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ユニヴァーシティ オブ コネチカット
ユニヴァーシティ オブ コネチカット
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Publication of JP2021505200A publication Critical patent/JP2021505200A/ja
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JP2020550047A 2017-12-08 2018-12-07 ゲノムインプリンティングの障害を治療するための組成物及び方法 Pending JP2021505200A (ja)

Applications Claiming Priority (3)

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US201762596397P 2017-12-08 2017-12-08
US62/596,397 2017-12-08
PCT/US2018/064517 WO2019113472A1 (en) 2017-12-08 2018-12-07 Compositions and methods for treating disorders of genomic imprinting

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JP2021505200A true JP2021505200A (ja) 2021-02-18
JP2021505200A5 JP2021505200A5 (enExample) 2022-01-11

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US (1) US12018255B2 (enExample)
EP (1) EP3720508A4 (enExample)
JP (1) JP2021505200A (enExample)
AU (1) AU2018380422A1 (enExample)
CA (1) CA3084810A1 (enExample)
WO (1) WO2019113472A1 (enExample)

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WO2013163628A2 (en) 2012-04-27 2013-10-31 Duke University Genetic correction of mutated genes
US9828582B2 (en) 2013-03-19 2017-11-28 Duke University Compositions and methods for the induction and tuning of gene expression
JP6929791B2 (ja) 2015-02-09 2021-09-01 デューク ユニバーシティ エピゲノム編集のための組成物および方法
WO2017066497A2 (en) 2015-10-13 2017-04-20 Duke University Genome engineering with type i crispr systems in eukaryotic cells
WO2017095967A2 (en) 2015-11-30 2017-06-08 Duke University Therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use
US20190127713A1 (en) 2016-04-13 2019-05-02 Duke University Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use
EP4275747A3 (en) 2016-07-19 2024-01-24 Duke University Therapeutic applications of cpf1-based genome editing
WO2019168950A1 (en) * 2018-02-27 2019-09-06 The University Of North Carolina At Chapel Hill Methods and compositions for treating angelman syndrome
EP4038204A4 (en) * 2019-10-02 2023-09-13 Duke University EPIGENETIC MODULATION OF GENOMIC TARGETS TO REGULATE THE EXPRESSION OF GENES ASSOCIATED WITH PWS
JP2025524469A (ja) 2022-06-24 2025-07-30 チューン セラピューティクス インコーポレイテッド 標的を定めた遺伝子抑制を介して低密度リポタンパク質を低減するための組成物、系、及び方法

Citations (1)

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WO2016170348A2 (en) * 2015-04-22 2016-10-27 Mina Therapeutics Limited Sarna compositions and methods of use

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US4554101A (en) 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
IL105914A0 (en) 1992-06-04 1993-10-20 Univ California Methods and compositions for in vivo gene therapy
US5679647A (en) 1993-08-26 1997-10-21 The Regents Of The University Of California Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
US20050244851A1 (en) * 2004-01-13 2005-11-03 Affymetrix, Inc. Methods of analysis of alternative splicing in human
US20100099746A1 (en) * 2006-12-18 2010-04-22 Kyowa Hakko Kirin Co., Ltd. Novel nucleic acid
GB0718542D0 (en) * 2007-09-22 2007-10-31 Univ Dundee Targeted modulation of gene expression
US9920317B2 (en) * 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs

Patent Citations (1)

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Non-Patent Citations (1)

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Title
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US12018255B2 (en) 2024-06-25
US20210171943A1 (en) 2021-06-10
EP3720508A1 (en) 2020-10-14
AU2018380422A1 (en) 2020-06-25
EP3720508A4 (en) 2021-09-01
WO2019113472A1 (en) 2019-06-13

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