JP2021177227A - Manufacturing method of simulated blood vessel - Google Patents

Manufacturing method of simulated blood vessel Download PDF

Info

Publication number
JP2021177227A
JP2021177227A JP2020082904A JP2020082904A JP2021177227A JP 2021177227 A JP2021177227 A JP 2021177227A JP 2020082904 A JP2020082904 A JP 2020082904A JP 2020082904 A JP2020082904 A JP 2020082904A JP 2021177227 A JP2021177227 A JP 2021177227A
Authority
JP
Japan
Prior art keywords
blood vessel
simulated blood
simulated
producing
printer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020082904A
Other languages
Japanese (ja)
Other versions
JP7458628B2 (en
Inventor
良博 橋爪
Yoshihiro Hashizume
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SWANY CO Ltd
Original Assignee
SWANY CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SWANY CO Ltd filed Critical SWANY CO Ltd
Priority to JP2020082904A priority Critical patent/JP7458628B2/en
Publication of JP2021177227A publication Critical patent/JP2021177227A/en
Application granted granted Critical
Publication of JP7458628B2 publication Critical patent/JP7458628B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Instructional Devices (AREA)

Abstract

To provide a manufacturing method of a simulated blood vessel having the same quality as an actual blood vessel.SOLUTION: A manufacturing method of a simulated blood vessel changes material properties with a 3D printer, to mold a simulated blood vessel 1 that imitates a blood vessel.SELECTED DRAWING: Figure 1

Description

本発明は、模擬血管の製造法に関する。 The present invention relates to a method for producing a simulated blood vessel.

従来、外科手術において、血管の切開、切開部の吻合、及び血管同士の吻合等の手技が行われている。このような手術には、熟練した技術が求められる。そこで、医者は動物の臓器にある血管、または模擬血管を用いて、血管の切開、切開部の吻合、及び血管同士の吻合等の練習を繰り返し行っていた。 Conventionally, in surgical operations, procedures such as incision of blood vessels, anastomosis of incisions, and anastomosis of blood vessels have been performed. Skilled skills are required for such surgery. Therefore, the doctor repeatedly practiced incision of blood vessels, anastomosis of incisions, and anastomosis of blood vessels using blood vessels in animal organs or simulated blood vessels.

特開２０１７−０５３８９７号公報Japanese Unexamined Patent Publication No. 2017-053897

しかしながら、動物の臓器にある血管を用いると、動物愛護の問題または感染症の問題、さらには廃棄問題等がある、また、模擬血管の材質が、たとえばゴム等であると（特許文献１）、実際の血管と同様の質感を維持できるものではなくなり、医者が行う練習が無駄になることもあった。 However, when blood vessels in animal organs are used, there are problems of animal welfare or infectious diseases, and further problems of disposal, and the material of simulated blood vessels is, for example, rubber (Patent Document 1). It was not possible to maintain the same texture as an actual blood vessel, and the practice performed by the doctor was sometimes wasted.

そこで本発明の目的は、実際の血管と同様の質感の模擬血管製造法を提供することである。 Therefore, an object of the present invention is to provide a simulated blood vessel manufacturing method having a texture similar to that of an actual blood vessel.

上記目的を達成するため、本発明の模擬血管の製造法は、３Ｄプリンタで材料物性を変えて造形した、血管を模した模擬血管の製造法である。 In order to achieve the above object, the method for producing a simulated blood vessel of the present invention is a method for producing a simulated blood vessel that imitates a blood vessel, which is formed by changing the material properties with a 3D printer.

ここで、複数の材料を用いて材料物性を変えて造形することとしても良い。 Here, a plurality of materials may be used to change the physical characteristics of the material for modeling.

また、材料物性が、血管壁と血管内部の硬さ、靭性または密度を含むこととしても良い。 Further, the material physical characteristics may include the hardness, toughness or density of the blood vessel wall and the inside of the blood vessel.

また、血管内部をサポート材としても良い。 Further, the inside of the blood vessel may be used as a support material.

また、血管壁の外側から血管内部へ注射針を貫通させ、血管内部に液体を注入することができることとしても良い。 Further, it may be possible to inject the liquid into the blood vessel by penetrating the injection needle from the outside of the blood vessel wall into the inside of the blood vessel.

また、模擬血管の外周をゲル膜で覆うこととしても良い。 Further, the outer circumference of the simulated blood vessel may be covered with a gel membrane.

本発明では、実際の血管と同様の質感の模擬血管製造法を提供することができる。 In the present invention, it is possible to provide a simulated blood vessel manufacturing method having a texture similar to that of an actual blood vessel.

本発明の実施の形態に係る模擬血管の断面斜視図である。It is sectional drawing of the simulated blood vessel which concerns on embodiment of this invention. 本発明の実施の形態に係る模擬血管を切断した後、ピンセットおよび鋏を使って、縫い針を用い、縫合糸で２つの模擬血管の切断面を縫い合わせる様子を示す図である。It is a figure which shows a mode that after cutting the simulated blood vessel which concerns on embodiment of this invention, the cut surface of two simulated blood vessels is sewn together with suture by using tweezers and scissors, and using a sewing needle. 血管壁を損傷させずに、縫合に成功した模擬血管を示す図である。It is a figure which shows the simulated blood vessel which succeeded in suturing without damaging the blood vessel wall. 本発明の実施の形態に係る模擬血管に、血管壁の外側から血管内部へ注射器の注射針を貫通させ、血管内部に液体を注入した状態を示す図である。It is a figure which shows the state which made the injection needle of a syringe penetrate into the simulated blood vessel which concerns on embodiment of this invention from the outside of the blood vessel wall into the inside of a blood vessel, and injected the liquid into the inside of a blood vessel. 本発明の実施の形態に係る模擬血管の外周をゲル膜で覆った状態を示す図である。It is a figure which shows the state which covered the outer circumference of the simulated blood vessel which concerns on embodiment of this invention with a gel membrane.

（模擬血管の製造法）
以下、本実施の形態について、図面に基づいて説明する。本実施の形態に係る模擬血管１の製造法は、３Ｄプリンタで材料物性を変えて造形して製造する。ここで、材料物性とは、機械的性質、熱的性質、電気的性質、磁気的性質または光学的性質から選ばれる１以上である。なお、三次元プリンタ（３Ｄプリンタ）等で形のあるものをつくることを「造形」（shaping）という。３Ｄプリンタは、三次元印刷機器、三次元プリンタ、または三次元造形機等と言われるものである。また、３Ｄプリンタは、三次元ＣＡＤ（computer-aided design）データに基づき、三次元の造形物を印刷し製造するものである。 (Manufacturing method of simulated blood vessels)
Hereinafter, the present embodiment will be described with reference to the drawings. The method for manufacturing the simulated blood vessel 1 according to the present embodiment is manufactured by changing the physical characteristics of the material with a 3D printer. Here, the material property is one or more selected from mechanical properties, thermal properties, electrical properties, magnetic properties, and optical properties. It should be noted that making a shape with a three-dimensional printer (3D printer) or the like is called "shaping". A 3D printer is called a three-dimensional printing device, a three-dimensional printer, a three-dimensional modeling machine, or the like. A 3D printer prints and manufactures a three-dimensional model based on three-dimensional CAD (computer-aided design) data.

３Ｄプリンタには、物性と色の違う複数の樹脂を、所定の位置に配置させることのできる機能を有するものを用いる。すなわち、３Ｄプリンタは、複数の材料を用いて材料物性を変えて造形する。３Ｄプリンタの印刷は、印刷する際に紫外線硬化樹脂等の光硬化性樹脂を一層ずつ形成し、その都度紫外線を照射して樹脂を硬化させる操作を繰り返すことで樹脂層を形成し、徐々に３次元形状を印刷、つまり造形していく。この光硬化性樹脂は、紫外線で硬化する樹脂以外に、ブラックライト、レーザー等の光で硬化する樹脂を含む。 As the 3D printer, a printer having a function of arranging a plurality of resins having different physical properties and colors at predetermined positions is used. That is, the 3D printer uses a plurality of materials and changes the physical characteristics of the material for modeling. In printing with a 3D printer, a photocurable resin such as an ultraviolet curable resin is formed layer by layer at the time of printing, and a resin layer is formed by repeating an operation of irradiating ultraviolet rays to cure the resin each time, and gradually 3 Dimensional shape is printed, that is, shaped. This photocurable resin includes a resin that is cured by light such as black light and a laser, in addition to a resin that is cured by ultraviolet rays.

三次元ＣＡＤデータは、例えば三次元スキャナで対象物をスキャニングすることで、対象物の三次元ＣＡＤデータの一部または全部が得られる。三次元スキャナとは、非接触式のものは、主に光つまり電磁波を使うもので、レーザーなどを対象物に照射してその反射光を解析し、三次元ＣＡＤデータを得るものである。また、血管の三次元ＣＡＤデータを得る場合には、ＭＲＩ（Magnetic Resonance Imaging）または、ＣＴ（Computed Tomography）スキャナ等を用いることができる。また、三次元ＣＡＤデータは、三次元スキャナまたはＭＲＩまたは、ＣＴスキャナ等を用いなくとも、コンピュータで三次元ＣＡＤのソフトウェアを操作して、モデリングにより、その一部または全部を得ることもできる。 As for the three-dimensional CAD data, a part or all of the three-dimensional CAD data of the object can be obtained by scanning the object with, for example, a three-dimensional scanner. The non-contact type scanner mainly uses light, that is, electromagnetic waves, and irradiates an object with a laser or the like to analyze the reflected light and obtain three-dimensional CAD data. Further, when obtaining three-dimensional CAD data of blood vessels, an MRI (Magnetic Resonance Imaging) or CT (Computed Tomography) scanner or the like can be used. Further, the 3D CAD data can be obtained in part or in whole by modeling the 3D CAD software by operating the 3D CAD software on a computer without using a 3D scanner, an MRI, a CT scanner, or the like.

そして、血管の形状を転写した三次元ＣＡＤデータを作成する。この三次元ＣＡＤデータは、血管の各部位が立体的形状で仕切られた複数の区画で設定される。そのため、模擬血管１は、各区画毎に樹脂が配置されるものである。模擬血管１の各区画の輪郭は、目視が困難である。各区画は、様々な形状に形成されている。その区画には、樹脂の物性、たとえば、硬さ、靭性または密度、表面の粗さ、含水量、耐熱性、熱伝導率等が特定のものとなるように、３Ｄプリンタの印刷状態を調節して、模擬血管１を造形する。このとき、三次元ＣＡＤデータには、区画の形成データおよび、各区画の樹脂の物性と色等を配置するデータ等が追加される。 Then, three-dimensional CAD data in which the shape of the blood vessel is transcribed is created. This three-dimensional CAD data is set by a plurality of compartments in which each part of the blood vessel is partitioned by a three-dimensional shape. Therefore, in the simulated blood vessel 1, the resin is arranged in each section. The contour of each section of the simulated blood vessel 1 is difficult to visually recognize. Each compartment is formed in various shapes. In that section, the printing condition of the 3D printer is adjusted so that the physical characteristics of the resin, for example, hardness, toughness or density, surface roughness, water content, heat resistance, thermal conductivity, etc. are specified. Then, the simulated blood vessel 1 is modeled. At this time, data for forming the compartments and data for arranging the physical properties and colors of the resin in each compartment are added to the three-dimensional CAD data.

ここで、造形された模擬血管１は、血管壁２と血管内部３に大別される。血管壁２の色はたとえば白色とし、血管内部３の色はたとえば血液の色に合わせて赤色にする。血管壁２と血管内部３の硬さ、靭性または密度は異なる。血管壁２はチューブ状の形状をしており、人間の血管とそっくりの硬さ、靭性または密度となるように、三次元ＣＡＤデータの、区画の形成データおよび、各区画の樹脂の物性を調整する。他方で、血管内部３はチューブ状の血管壁２を３Ｄプリンタで造形する際に、そのチューブ状の形状を維持するためのサポート材とする。 Here, the modeled simulated blood vessel 1 is roughly classified into a blood vessel wall 2 and a blood vessel inside 3. The color of the blood vessel wall 2 is, for example, white, and the color of the blood vessel inside 3 is, for example, red to match the color of blood. The hardness, toughness or density of the blood vessel wall 2 and the blood vessel internal 3 are different. The blood vessel wall 2 has a tubular shape, and the compartment formation data of the three-dimensional CAD data and the physical properties of the resin of each compartment are adjusted so that the hardness, toughness, or density is similar to that of a human blood vessel. do. On the other hand, the inside 3 of the blood vessel is used as a support material for maintaining the tubular shape when the tubular blood vessel wall 2 is modeled by a 3D printer.

サポート材とは、造形中に、造形しようとする造形物の形状を支えるための材料であり、通常は造形が終了すれば除去するものである。本実施の形態では、チューブ状の血管壁２を造形する際に血管内部３の部分にサポート材を入れて血管壁２を支える。本実施の形態では、敢えてそのサポート材を血管内部３の模擬血液として活用しようとするものである。血管内部３の模擬血液をサポート材で代替できると考えた理由は、サポート材の樹脂密度は、通常低いため、充分血液の代替物（模擬血液）として活用できると考えたためである。 The support material is a material for supporting the shape of the modeled object to be modeled during modeling, and is usually removed when the modeling is completed. In the present embodiment, when the tubular blood vessel wall 2 is formed, a support material is inserted in the portion inside the blood vessel 3 to support the blood vessel wall 2. In the present embodiment, the support material is intentionally used as simulated blood inside the blood vessel 3. The reason why the simulated blood inside the blood vessel 3 can be replaced with the support material is that the resin density of the support material is usually low, so that it can be sufficiently utilized as a substitute for blood (simulated blood).

（模擬血管の主な使用法）
図２に示すように、医師が模擬血管１を切断した後、ピンセット４および鋏５を使って、縫い針６を用い、縫合糸７で２つの模擬血管１の切断面８を縫い合わせる練習をする。鋏５は、縫い針６および縫合糸７を掴んで動かすためのものである。ピンセット４は、模擬血管１を保持するものである。鋏５はたとえば医師の右手９で操作し、ピンセット４は、医師の左手９で操作する。血管内部３の模擬血液は、このとき除去している。 (Main usage of simulated blood vessels)
As shown in FIG. 2, after the doctor cuts the simulated blood vessel 1, the tweezers 4 and the scissors 5 are used to practice sewing the cut surfaces 8 of the two simulated blood vessels 1 with the suture thread 7 using the sewing needle 6. .. The scissors 5 are for grasping and moving the sewing needle 6 and the suture thread 7. The tweezers 4 hold the simulated blood vessel 1. The scissors 5 are operated by, for example, the doctor's right hand 9, and the tweezers 4 are operated by the doctor's left hand 9. The simulated blood inside the blood vessel 3 is removed at this time.

模擬血管１は、人間の血管とそっくりの硬さ、靭性または密度となるようにしているため、縫合糸７が血管壁２を強く引っ張ることにより、血管壁２を破損したりすると、縫合に失敗したことに気付くことができる。そのような縫合の練習を繰り返すことができる。たとえば図３に、血管壁２を損傷させずに、縫合に成功した模擬血管１を示す。 Since the simulated blood vessel 1 has a hardness, toughness, or density similar to that of a human blood vessel, if the suture thread 7 strongly pulls the blood vessel wall 2 and damages the blood vessel wall 2, the suture fails. You can notice what you have done. Such suturing exercises can be repeated. For example, FIG. 3 shows a simulated blood vessel 1 that was successfully sutured without damaging the blood vessel wall 2.

（本実施の形態によって得られる主な効果）
本実施の形態では、実際の血管と同様の質感の模擬血管製造法を提供することができた。これによって、医師は、手術の際の血管の取り扱いの技術を磨く練習をすることができる。 (Main effects obtained by this embodiment)
In the present embodiment, it was possible to provide a simulated blood vessel manufacturing method having a texture similar to that of an actual blood vessel. This allows doctors to practice improving their skills in handling blood vessels during surgery.

本実施の形態では、３Ｄプリンタを用いて模擬血管１を製造している。３Ｄプリンタは、三次元ＣＡＤデータを驚くほど忠実に印刷物、つまり造形物の形状に反映できる特徴を有する。３Ｄプリンタは、１４μｍの細かい凹凸も表現できると言われている。そのため、人間の血管の細かい凹凸を実現する模擬血管１を製造可能である。この細かい凹凸を忠実に転写する効果は、従来の金型等で成形した場合には、到底得られず、３Ｄプリンタを用いて製造した場合に初めて得られる効果である。しかも、３Ｄプリンタを用いた模擬血管１の製造に要するコストおよび時間は、従来の金型の約１／６とすることができる。 In the present embodiment, the simulated blood vessel 1 is manufactured by using a 3D printer. The 3D printer has a feature that the three-dimensional CAD data can be reflected in the shape of the printed matter, that is, the modeled matter, with surprising fidelity. It is said that a 3D printer can express fine irregularities of 14 μm. Therefore, it is possible to manufacture a simulated blood vessel 1 that realizes fine irregularities of human blood vessels. The effect of faithfully transferring these fine irregularities cannot be obtained when molded with a conventional mold or the like, and is the effect obtained only when manufactured using a 3D printer. Moreover, the cost and time required to manufacture the simulated blood vessel 1 using the 3D printer can be about 1/6 of that of the conventional mold.

本実施の形態によって、物性の違う複数の樹脂を組み合わせることで、模擬血管１の各区画の硬さ、表面の粗さ、耐熱性、弾力性および熱伝導率等を変えることができる。人間の血管には、静脈または動脈、毛細血管等の種々の血管があり、それらの物性は異なるところ、その異なる物性を実現できる。 According to this embodiment, the hardness, surface roughness, heat resistance, elasticity, thermal conductivity, etc. of each section of the simulated blood vessel 1 can be changed by combining a plurality of resins having different physical characteristics. Human blood vessels include various blood vessels such as veins, arteries, and capillaries, and where their physical characteristics are different, the different physical characteristics can be realized.

３Ｄプリンタ（物性と色の違う複数の樹脂を、所定の位置に配置させることのできる機能を有するもの）は、樹脂を蓄積および供給するインクカートリッジを６本まで搭載でき、各々のカートリッジから樹脂を同時に噴射可能である。そのため、模擬血管１の製造に必要な樹脂を、一度の印刷作業で、繋ぎ部材を必要としない一体造形物（一つのかたまり）として配置し、模擬血管１を製造できる。 A 3D printer (which has the function of arranging multiple resins with different physical characteristics and colors at predetermined positions) can be equipped with up to six ink cartridges that store and supply resin, and the resin can be removed from each cartridge. It is possible to inject at the same time. Therefore, the resin required for manufacturing the simulated blood vessel 1 can be arranged as an integrally modeled object (one block) that does not require a connecting member in one printing operation, and the simulated blood vessel 1 can be manufactured.

また、本実施の形態では、血管内部３をサポート材としている。そのことにより、製造が容易になる。 Further, in the present embodiment, the inside 3 of the blood vessel is used as a support material. This facilitates manufacturing.

（他の形態）
上述した本実施の形態に係る模擬血管１の製造法は、本発明の好適な形態の一例ではあるが、これに限定されるものではなく本発明の要旨を変更しない範囲において種々の変形実施が可能である。 (Other forms)
The method for producing a simulated blood vessel 1 according to the above-described embodiment is an example of a preferred embodiment of the present invention, but the present invention is not limited to this, and various modifications can be made without changing the gist of the present invention. It is possible.

本実施の形態では、複数の材料を用いて模擬血管１を製造している。しかし、一つの材料で模擬血管１を製造しても良い。 In the present embodiment, the simulated blood vessel 1 is manufactured using a plurality of materials. However, the simulated blood vessel 1 may be manufactured from one material.

また、模擬血管１は、人間の血管にそっくりにする材料物性を、血管壁と血管内部の硬さ、靭性または密度としている。しかし、たとえば模擬血管１の、人間の血管にそっくりにする材料物性を、血管壁と血管内部の硬さだけ、あるいは靭性だけとしてもよい。 Further, in the simulated blood vessel 1, the material physical characteristics that are similar to those of a human blood vessel are the hardness, toughness, or density of the blood vessel wall and the inside of the blood vessel. However, for example, the physical characteristics of the simulated blood vessel 1 that resembles a human blood vessel may be only the hardness of the blood vessel wall and the inside of the blood vessel, or only the toughness.

また、模擬血管１は、血管内部３をサポート材としている。しかし、血管内部３のサポート材を除去しても良く、その除去したサポート材の代わりに血液を模した赤い液体等を血管内部３に入れても良い。 Further, the simulated blood vessel 1 uses the inside 3 of the blood vessel as a support material. However, the support material inside the blood vessel 3 may be removed, and instead of the removed support material, a red liquid or the like imitating blood may be put into the inside 3 of the blood vessel.

本実施の形態では、模擬血管１は、血管壁２の外側から血管内部３へ注射針を貫通させ、血管内部３に液体を注入することができるようにしても良い。このとき、またはこのときに限らず、模擬血管１の片端または両端を塞ぐようにしても良い。これは、たとえば高血圧の血管を模した模擬血管１が欲しいときに、それを実現できる。図４に模擬血管１に、血管壁２の外側から血管内部３へ注射器１１の注射針１２を貫通させ、血管内部３に液体を注入した状態を示す。 In the present embodiment, the simulated blood vessel 1 may be capable of injecting a liquid into the inside of the blood vessel 3 by penetrating an injection needle from the outside of the blood vessel wall 2 into the inside of the blood vessel 3. At this time, or not limited to this time, one end or both ends of the simulated blood vessel 1 may be closed. This can be achieved, for example, when a simulated blood vessel 1 that imitates a blood vessel with high blood pressure is desired. FIG. 4 shows a state in which the injection needle 12 of the syringe 11 is passed through the simulated blood vessel 1 from the outside of the blood vessel wall 2 to the inside 3 of the blood vessel, and the liquid is injected into the inside 3 of the blood vessel.

本実施の形態では、模擬血管１の外周をゲル膜で覆っても良い。人間の臓器等の周囲の血管は、血管鞘で覆われていることが多い。その状態を再現し、より本物の人間の血管に近い模擬血管１で手術の練習ができる。図５には、模擬血管１の外周をゲル膜１３で覆った状態を示している。ゲル膜１３を模擬血管１で覆う際には、水等の液体をゲル膜１３に含ませると、より本物の人間の血管に近くなる。 In the present embodiment, the outer circumference of the simulated blood vessel 1 may be covered with a gel film. The surrounding blood vessels such as human organs are often covered with a vascular sheath. By reproducing that state, surgery can be practiced with a simulated blood vessel 1 that is closer to a real human blood vessel. FIG. 5 shows a state in which the outer circumference of the simulated blood vessel 1 is covered with a gel film 13. When covering the gel membrane 13 with the simulated blood vessel 1, if a liquid such as water is contained in the gel membrane 13, it becomes closer to a real human blood vessel.

１ 模擬血管
２ 血管壁
３ 血管内部
１２ 注射針
１３ ゲル膜
1 Simulated blood vessel 2 Blood vessel wall 3 Inside the blood vessel 12 Injection needle 13 Gel membrane

Claims (6)

３Ｄプリンタで材料物性を変えて造形した、血管を模した模擬血管の製造法。 A method for manufacturing a simulated blood vessel that imitates a blood vessel, which is modeled by changing the physical characteristics of the material with a 3D printer. 請求項１に記載の模擬血管の製造法において、
複数の材料を用いて前記材料物性を変えて前記造形した、血管を模した模擬血管の製造法。 In the method for producing a simulated blood vessel according to claim 1,
A method for producing a simulated blood vessel that imitates a blood vessel, which is formed by changing the physical characteristics of the material using a plurality of materials. 請求項１または２に記載の模擬血管の製造法において、
前記材料物性が、血管壁と血管内部の硬さ、靭性または密度を含む、模擬血管の製造法。 In the method for producing a simulated blood vessel according to claim 1 or 2.
A method for producing a simulated blood vessel, wherein the material properties include hardness, toughness or density inside the blood vessel wall and the blood vessel. 請求項１から３のいずれか１項に記載の模擬血管の製造法において、
前記血管内部をサポート材とする、模擬血管の製造法。 In the method for producing a simulated blood vessel according to any one of claims 1 to 3.
A method for producing a simulated blood vessel, which uses the inside of the blood vessel as a support material. 請求項３または４に記載の模擬血管の製造法において、
前記血管壁の外側から前記血管内部へ注射針を貫通させ、前記血管内部に液体を注入することができる、模擬血管の製造法。 In the method for producing a simulated blood vessel according to claim 3 or 4.
A method for producing a simulated blood vessel, which allows a liquid to be injected into the blood vessel by penetrating an injection needle from the outside of the blood vessel wall into the inside of the blood vessel. 請求項１から５のいずれか１項に記載の模擬血管の製造法において、
前記模擬血管の外周をゲル膜で覆った、模擬血管の製造法。 In the method for producing a simulated blood vessel according to any one of claims 1 to 5.
A method for producing a simulated blood vessel, wherein the outer circumference of the simulated blood vessel is covered with a gel membrane.
JP2020082904A 2020-05-09 2020-05-09 Manufacturing method of simulated blood vessels Active JP7458628B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2020082904A JP7458628B2 (en) 2020-05-09 2020-05-09 Manufacturing method of simulated blood vessels

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2020082904A JP7458628B2 (en) 2020-05-09 2020-05-09 Manufacturing method of simulated blood vessels

Publications (2)

Publication Number Publication Date
JP2021177227A true JP2021177227A (en) 2021-11-11
JP7458628B2 JP7458628B2 (en) 2024-04-01

Family

ID=78409445

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020082904A Active JP7458628B2 (en) 2020-05-09 2020-05-09 Manufacturing method of simulated blood vessels

Country Status (1)

Country Link
JP (1) JP7458628B2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009273508A (en) * 2008-05-12 2009-11-26 Ono Kogyo:Kk Method of manufacturing soft blood vessel model for surgery simulation
JP2013250453A (en) * 2012-05-31 2013-12-12 Higashi Nippon Gakuen Hokkaido Iryo Daigaku Injection simulator
JP6172370B1 (en) * 2016-11-10 2017-08-02 株式会社東穂 A simulated tissue body for practicing puncture technique and its use.
JP2018035271A (en) * 2016-08-31 2018-03-08 株式会社リコー Hydrogel structure, and production method and use of the same
WO2019021292A1 (en) * 2017-07-28 2019-01-31 Stratasys Ltd. Method and system for fabricating object featuring properties of a blood vessel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018203561A1 (en) 2017-05-02 2018-11-08 国立大学法人東北大学 Luminal organ model unit and method for manufacturing luminal organ model unit

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009273508A (en) * 2008-05-12 2009-11-26 Ono Kogyo:Kk Method of manufacturing soft blood vessel model for surgery simulation
JP2013250453A (en) * 2012-05-31 2013-12-12 Higashi Nippon Gakuen Hokkaido Iryo Daigaku Injection simulator
JP2018035271A (en) * 2016-08-31 2018-03-08 株式会社リコー Hydrogel structure, and production method and use of the same
JP6172370B1 (en) * 2016-11-10 2017-08-02 株式会社東穂 A simulated tissue body for practicing puncture technique and its use.
WO2019021292A1 (en) * 2017-07-28 2019-01-31 Stratasys Ltd. Method and system for fabricating object featuring properties of a blood vessel

Also Published As

Publication number Publication date
JP7458628B2 (en) 2024-04-01

Similar Documents

Publication Publication Date Title
KR100614147B1 (en) Three-dimensional model
EP3251811B1 (en) Method of producing a phantom and phantom
KR100713726B1 (en) Three-dimensional model
US20140017651A1 (en) Method for Manufacturing Three-Dimensional Molded Model and Support Tool for Medical Treatment, Medical Training, Research, and Education
US10350833B1 (en) Methods and systems for creating anatomical models
Mitsouras et al. 3D printing technologies
US20200316850A1 (en) Anatomical silicon models and additive manufacturing thereof
US10864659B1 (en) Methods and systems for creating anatomical models
JP7365020B2 (en) Method for manufacturing objects with gel
Żukowska et al. Methodology of low cost rapid manufacturing of anatomical models with material imitation of soft tissues
EP3424034A1 (en) Method of assessing the performance of a human or robot carrying out a medical procedure and assessment tool
US11705020B2 (en) Method of manufacturing a bio-model comprising a synthetic skin layer and bio-model comprising a synthetic skin layer
JP7437826B2 (en) Organ model for surgical practice
JP7458628B2 (en) Manufacturing method of simulated blood vessels
Kashapov et al. The application of additive technologies in creation a medical simulator-trainer of the human head operating field
Riedle et al. Generation of 3D silicone models of anatomic soft tissue structures-A comparison of direct 3D printing and molding techniques
Stefano et al. 3D Stereolithography for hollow cerebral aneurysm models
Yao et al. Design and 3D Printing of Liver Surgical Guide Template Based on Mimics Liver Model Reconstruction
US20230059287A1 (en) Design and Manufacturing Process to Create Modular Surgical Simulators for Training
Aseni et al. Hybrid additive fabrication of a transparent liver with biosimilar haptic response for pre-operative planning. Diagnostics. 2021; 11: 1734
Kulkarni et al. Generation of a 3D printed brain model from MRI scan data to assist in Brain Surgery using open source tools
Liacouras et al. 3D Printing Technologies and Materials
GB2624617A (en) Ultrasonography Training Phantom
JP2006119435A (en) Manufacturing method for human body affected part entity model
Ramin Automated design of trabecular structures

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230227

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20231124

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20231124

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240116

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240229

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240312

R150 Certificate of patent or registration of utility model

Ref document number: 7458628

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150