JP2021156891A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2021156891A5 JP2021156891A5 JP2021091285A JP2021091285A JP2021156891A5 JP 2021156891 A5 JP2021156891 A5 JP 2021156891A5 JP 2021091285 A JP2021091285 A JP 2021091285A JP 2021091285 A JP2021091285 A JP 2021091285A JP 2021156891 A5 JP2021156891 A5 JP 2021156891A5
- Authority
- JP
- Japan
- Prior art keywords
- output signal
- cells
- time
- subject
- dementia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 208000024827 Alzheimer disease Diseases 0.000 claims 27
- 210000004027 cell Anatomy 0.000 claims 16
- 239000000104 diagnostic biomarker Substances 0.000 claims 14
- 206010012289 Dementia Diseases 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 239000000090 biomarker Substances 0.000 claims 6
- 208000010877 cognitive disease Diseases 0.000 claims 5
- 208000027061 mild cognitive impairment Diseases 0.000 claims 5
- 102000003923 Protein Kinase C Human genes 0.000 claims 4
- 108090000315 Protein Kinase C Proteins 0.000 claims 4
- 238000013425 morphometry Methods 0.000 claims 2
- 230000002093 peripheral effect Effects 0.000 claims 2
- 238000012886 linear function Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 230000002250 progressing effect Effects 0.000 claims 1
- 210000001626 skin fibroblast Anatomy 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662298182P | 2016-02-22 | 2016-02-22 | |
| US62/298,182 | 2016-02-22 | ||
| JP2018563394A JP7134874B2 (ja) | 2016-02-22 | 2017-02-22 | 軽度認知障害（ｍｃｉ）の診断、アルツハイマー病（ａｄ）型認知症の発症の予測、ならびにｍｃｉの処置または認知症発症の予防のための薬剤のスクリーニングおよびモニタリング |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563394A Division JP7134874B2 (ja) | 2016-02-22 | 2017-02-22 | 軽度認知障害（ｍｃｉ）の診断、アルツハイマー病（ａｄ）型認知症の発症の予測、ならびにｍｃｉの処置または認知症発症の予防のための薬剤のスクリーニングおよびモニタリング |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021156891A JP2021156891A (ja) | 2021-10-07 |
| JP2021156891A5 true JP2021156891A5 (https=) | 2022-03-01 |
| JP7279110B2 JP7279110B2 (ja) | 2023-05-22 |
Family
ID=58361076
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563394A Active JP7134874B2 (ja) | 2016-02-22 | 2017-02-22 | 軽度認知障害（ｍｃｉ）の診断、アルツハイマー病（ａｄ）型認知症の発症の予測、ならびにｍｃｉの処置または認知症発症の予防のための薬剤のスクリーニングおよびモニタリング |
| JP2021091285A Active JP7279110B2 (ja) | 2016-02-22 | 2021-05-31 | 軽度認知障害（ｍｃｉ）の診断、アルツハイマー病（ａｄ）型認知症の発症の予測、ならびにｍｃｉの処置または認知症発症の予防のための薬剤のスクリーニングおよびモニタリング |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563394A Active JP7134874B2 (ja) | 2016-02-22 | 2017-02-22 | 軽度認知障害（ｍｃｉ）の診断、アルツハイマー病（ａｄ）型認知症の発症の予測、ならびにｍｃｉの処置または認知症発症の予防のための薬剤のスクリーニングおよびモニタリング |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20190041404A1 (https=) |
| EP (1) | EP3420363A1 (https=) |
| JP (2) | JP7134874B2 (https=) |
| CA (1) | CA3014906C (https=) |
| WO (1) | WO2017147114A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3600027B1 (en) | 2017-03-31 | 2026-02-18 | Neurodiagnostics LLC | Lymphocyte-based morphometric test for alzheimer's disease |
| US11621087B2 (en) * | 2019-09-24 | 2023-04-04 | International Business Machines Corporation | Machine learning for amyloid and tau pathology prediction |
| CN111091906B (zh) * | 2019-10-31 | 2023-06-20 | 中电药明数据科技(成都)有限公司 | 一种基于真实世界数据的辅助医疗诊断方法及系统 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7595167B2 (en) | 2005-10-11 | 2009-09-29 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's disease-specific alterations of the Erk1/Erk2 phosphorylation ratio |
| US20090029873A1 (en) | 2005-10-11 | 2009-01-29 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's Disease-Specific Alterations of the Erk1/Erk2 Phosphorylation Ratio-Alzheimer's Disease-Specific Molecular Biomarkers (Adsmb) |
| EP2483695A2 (en) * | 2009-10-02 | 2012-08-08 | Blanchette Rockefeller Neurosciences, Institute | Abnormal alterations of pkc isozymes processing in alzheimer's disease peripheral cells |
| EP2483684B1 (en) | 2009-10-02 | 2018-04-18 | Blanchette Rockefeller Neurosciences, Institute | Fibroblast growth patterns to diagnose alzheimer's disease |
| US20140038186A1 (en) | 2010-02-22 | 2014-02-06 | Tapan Kumar Khan | Alzheimer's disease-specific alterations of protein kinase c epsilon (pkc-epsilon) protein levels |
| US20120141498A1 (en) * | 2010-12-02 | 2012-06-07 | United States Government As Represented By The Department Of Veterans Affairs | Use of pkc isozymes for diagnosis and treatment of neuroblastoma |
| CA2855932A1 (en) | 2011-11-13 | 2013-05-16 | Blanchette Rockefeller Neurosciences Institute | Pkc activators and combinations thereof |
| US20170023552A1 (en) | 2014-01-03 | 2017-01-26 | Blanchette Rockefeller Neurosciences Institute | Convergence of aggregation rate with validated peripheral diagnostic for alzheimer's disease |
-
2017
- 2017-02-22 WO PCT/US2017/018810 patent/WO2017147114A1/en not_active Ceased
- 2017-02-22 US US16/077,766 patent/US20190041404A1/en not_active Abandoned
- 2017-02-22 EP EP17712270.2A patent/EP3420363A1/en active Pending
- 2017-02-22 CA CA3014906A patent/CA3014906C/en active Active
- 2017-02-22 JP JP2018563394A patent/JP7134874B2/ja active Active
-
2021
- 2021-05-31 JP JP2021091285A patent/JP7279110B2/ja active Active
-
2024
- 2024-07-03 US US18/763,515 patent/US12601750B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021156891A5 (https=) | ||
| Thomas et al. | Word-list intrusion errors predict progression to mild cognitive impairment. | |
| Lehmann et al. | Application and comparison of classification algorithms for recognition of Alzheimer's disease in electrical brain activity (EEG) | |
| Gavett et al. | The δ latent dementia phenotype in the uniform data set: Cross-validation and extension. | |
| Rusz et al. | Distinctive speech signature in cerebellar and parkinsonian subtypes of multiple system atrophy | |
| JP2011516046A5 (https=) | ||
| JP2021517005A (ja) | 胃腸状態の可能性を示すための方法およびシステム | |
| Kang et al. | Principal dynamic mode analysis of EEG data for assisting the diagnosis of Alzheimer’s disease | |
| Gökçay et al. | Binary classification using neural and clinical features: an application in fibromyalgia with likelihood-based decision level fusion | |
| CN107045876A (zh) | 一种基于语音的帕金森症严重程度诊断方法 | |
| US10740655B2 (en) | Integrative prediction of a cognitive evolution of a subject | |
| Thompson et al. | Digital clock drawing as an Alzheimer's disease susceptibility biomarker: associations with genetic risk score and APOE in older adults | |
| KR20210076594A (ko) | 수치 데이터를 이용한 수면무호흡증 예측 모델의 생성 방법 및 이 모델을 이용한 수면무호흡증 예측 방법 | |
| JP2019525133A5 (https=) | ||
| CN116473514B (zh) | 基于足底压力的自适应有向时空图神经网络的帕金森疾病检测方法 | |
| CN116153502A (zh) | 一种干预有效性预测的方法、系统及其应用 | |
| CN112568912B (zh) | 一种基于非侵入式脑电信号的抑郁症生物标记物辨识方法 | |
| Gavett et al. | Predicting cognitive decline and conversion to Alzheimer’s disease in older adults using the NAB List Learning test | |
| WO2025093006A1 (zh) | IgA免疫活动性指数时间序列在诊断IgA肾病中的应用 | |
| Kurt et al. | Musical feature based classification of Parkinson's disease using dysphonic speech | |
| Panda et al. | Impact of machine learning and prediction models in the diagnosis of oral health conditions | |
| Mathkunti et al. | Brain Disease Parkinson's Diagnosis using VGG-16 and VGG-19 with Spiral and Waves drawings as Input | |
| CN113545771B (zh) | 一种基于足底压力的集成k近邻帕金森病定量诊断系统 | |
| Hamadicharef et al. | Performance evaluation and fusion of methods for early detection of Alzheimer Disease | |
| Gonzalez-Moreira et al. | Prosodic speech analysis to identify mild cognitive impairment |