JP2020501829A - 薬剤送達デバイス - Google Patents
薬剤送達デバイス Download PDFInfo
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- JP2020501829A JP2020501829A JP2019534089A JP2019534089A JP2020501829A JP 2020501829 A JP2020501829 A JP 2020501829A JP 2019534089 A JP2019534089 A JP 2019534089A JP 2019534089 A JP2019534089 A JP 2019534089A JP 2020501829 A JP2020501829 A JP 2020501829A
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M2005/3022—Worn on the body, e.g. as patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3337—Controlling, regulating pressure or flow by means of a valve by-passing a pump
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3633—General characteristics of the apparatus related to heating or cooling thermally insulated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8218—Gas operated
- A61M2205/8231—Gas operated using electrochemical gas generating device for the driving gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
- A61M2230/201—Glucose concentration
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (19)
- 薬剤送達デバイス(10、110)であって:
薬剤受容要素(14)と;
該薬剤受容要素(14)の方に流体蒸気を導くように構成された流体出口(29b)を有する少なくとも1つの流体チャンバ(16)と;
該少なくとも1つの流体チャンバ(16)内の流体を加熱するための加熱要素(30)と;
を含み、
該デバイス(10)は、使用のとき、加熱要素(30)が、少なくとも1つの流体チャンバ(16)内の流体を少なくとも部分的に蒸発させるように流体を加熱し、それによって流体が少なくとも1つの流体チャンバ(16)から流体出口(29b)を通って薬剤受容要素(14)の方へと排出されて患者の皮膚の方に向けて薬剤を同伴するほどまで少なくとも1つの流体チャンバ(16)内の蒸気圧が上昇するように、構成される、
前記薬剤送達デバイス。 - 流体出口(29b)は、微小ノズルを含む、請求項1に記載の薬剤送達デバイス(10)。
- 流体出口(29b)は、逆止弁(33)を含む、請求項1に記載の薬剤送達デバイス(110)。
- 加熱要素(30)は、抵抗式であり、流体を加熱するために電流パルスを受けるように構成される、請求項1〜3のいずれか1項に記載の薬剤送達デバイス(10、110)。
- 少なくとも1つの流体チャンバ(16)は、放熱を防ぐように断熱要素(31)を含む、請求項1〜4のいずれか1項に記載の薬剤送達デバイス(10、110)。
- 流体リザーバ(15)と、
該流体リザーバ(15)から少なくとも1つの流体チャンバ(16)に流体をポンプ輸送するための流体ポンプ機構(27)と
を含む、請求項1〜5のいずれか1項に記載の薬剤送達デバイス(10、110)。 - 薬剤受容要素(14)は、多孔質部材(35)を含み、該多孔質部材は、薬剤を保持するように構成され、使用のとき薬剤が、多孔質部材(35)から、少なくとも1つの流体チャンバ(16)の流体出口(29b)から排出された流体内に同伴されて患者の皮膚の方へと通過するように、配置される、請求項1〜6のいずれか1項に記載の薬剤送達デバイス(10)。
- 薬剤受容要素(14)は、分配篩(32)を含み、該分配篩は、使用のとき薬剤が、該分配篩(32)の中を、少なくとも1つの流体チャンバ(16)の流体出口(29b)から排出された流体内に同伴されて患者の皮膚の方へと通過するように、配置される、請求項1〜7のいずれか1項に記載の薬剤送達デバイス(10)。
- 薬剤受容要素(14)は、薬剤を受けるように構成されたチャンバ(36)を含み、該チャンバ(36)は、薬剤を該チャンバ(36)から患者に送達するための送達部分(34)を含む、請求項1〜6のいずれか1項に記載の薬剤送達デバイス(110)。
- 複数の流体チャンバ(16)を含む、
請求項1〜9のいずれか1項に記載の薬剤送達デバイス(10、110)。 - 薬剤のカートリッジ(15)を含む、
請求項1〜10のいずれか1項に記載の薬剤送達デバイス(10、110)。 - 患者への薬剤送達を制御するプロセッサ(18)を含む、
請求項1〜11のいずれか1項に記載の薬剤送達デバイス(10、110)。 - 薬剤送達デバイス(10)は、インスリン送達デバイスである、請求項1〜12のいずれか1項に記載の薬剤送達デバイス(10、110)。
- プロセッサ(18)が患者へのインスリン送達を制御するように、プロセッサ(18)に患者の血糖に関するデータを送るように構成された血糖センサを含む、
請求項12または13に記載の薬剤送達デバイス(10、110)。 - 薬剤受容要素(14)は、ガス透過性である、請求項1〜14のいずれか1項に記載の薬剤送達デバイス(10、110)。
- 流体が少なくとも1つの流体チャンバ(16)から流体出口(29b)を通って排出されて薬剤受容要素(14)を通過するように構成された、請求項1〜15のいずれか1項に記載の薬剤送達デバイス(10、110)。
- 薬剤が薬剤受容要素(14)へと輸送され、その後に加熱要素(30)が少なくとも1つの流体チャンバ(16)内の流体を加熱して該流体を少なくとも部分的に蒸発させるように構成された、請求項1〜16のいずれか1項に記載の薬剤送達デバイス(10、110)。
- 流体チャンバ(16)であって、請求項1〜17のいずれか1項に記載の薬剤送達デバイス(10)において使用されるための、前記流体チャンバ。
- 薬剤を送達する方法であって、
薬剤受容要素(14)と、該薬剤受容要素(14)の方に流体蒸気を導くように構成された流体出口(29b)を有する少なくとも1つの流体チャンバ(16)と、該少なくとも1つの流体チャンバ(16)内の流体を加熱するための加熱要素(30)とを含む薬剤送達デバイス(10、110)を使用すること、を含み、
加熱要素(30)を使用して、少なくとも1つの流体チャンバ(16)内の流体を少なくとも部分的に蒸発させるように流体を加熱し、それによって該流体が少なくとも1つの流体チャンバ(16)から流体出口(29b)を通って薬剤受容要素(14)の方へと排出されて患者の皮膚の方に向けて薬剤を同伴するほどまで少なくとも1つの流体チャンバ(16)内の蒸気圧が上昇するようにすること
を含む、前記方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16206615.3 | 2016-12-23 | ||
EP16206615.3A EP3338835A1 (en) | 2016-12-23 | 2016-12-23 | Medicament delivery device |
PCT/EP2017/084143 WO2018115310A1 (en) | 2016-12-23 | 2017-12-21 | Medicament delivery device |
Publications (2)
Publication Number | Publication Date |
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JP2020501829A true JP2020501829A (ja) | 2020-01-23 |
JP7305540B2 JP7305540B2 (ja) | 2023-07-10 |
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Application Number | Title | Priority Date | Filing Date |
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JP2019534089A Active JP7305540B2 (ja) | 2016-12-23 | 2017-12-21 | 薬剤送達デバイス |
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US (1) | US11607487B2 (ja) |
EP (2) | EP3338835A1 (ja) |
JP (1) | JP7305540B2 (ja) |
CN (1) | CN110087715B (ja) |
WO (1) | WO2018115310A1 (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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PT1762259E (pt) | 2005-09-12 | 2010-12-10 | Unomedical As | Insersor para um conjunto de infusão com uma primeira e uma segunda unidades de mola |
US10194938B2 (en) | 2011-03-14 | 2019-02-05 | UnoMedical, AS | Inserter system with transport protection |
EP3405230A1 (en) | 2016-01-19 | 2018-11-28 | Unomedical A/S | Cannula and infusion devices |
CN109893720B (zh) * | 2019-03-01 | 2021-02-19 | 浙江师范大学 | 一种压电叠堆式气动注射系统 |
AU2020279722A1 (en) | 2019-05-20 | 2021-11-18 | Unomedical A/S | Rotatable infusion device and methods thereof |
Citations (3)
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US20050154369A1 (en) * | 2002-04-05 | 2005-07-14 | Martin Broullette | Needleless syringe for the subcutaneous injection of droplets of liquid substances |
JP2006524120A (ja) * | 2003-04-21 | 2006-10-26 | ストラテージェント ライフ サイエンシズ | マイクロジェットで反復的に薬物を搬送する装置および方法 |
JP2012223562A (ja) * | 2011-04-19 | 2012-11-15 | Palo Alto Research Center Inc | コリメートされたガス流及び粒子源を用いる送達機器及び方法 |
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US6836678B2 (en) | 2003-02-13 | 2004-12-28 | Xiang Zheng Tu | Non-invasive blood glucose monitor |
CN101312760B (zh) | 2005-09-26 | 2013-01-30 | 利兹大学 | 药物输送 |
CA3059992C (en) * | 2006-02-09 | 2022-04-12 | Dean Kamen | Peripheral systems |
US20110092898A1 (en) * | 2009-10-21 | 2011-04-21 | Texas Instruments Incorporated | Medicine injection into skin with heater chip |
WO2011115328A1 (ko) * | 2010-03-16 | 2011-09-22 | 서울대학교 산학협력단 | 마이크로젯 약물 전달 시스템 |
CN104066675A (zh) * | 2011-11-17 | 2014-09-24 | 赛诺菲-安万特德国有限公司 | 装置、糖尿病治疗系统和使食物变甜的方法 |
US9610398B2 (en) | 2011-11-22 | 2017-04-04 | Incube Labs, Llc | Implantable solid-liquid drug delivery apparatus, formulations, and methods of use |
JP6313294B2 (ja) * | 2012-06-25 | 2018-04-18 | フィッシャー アンド ペイケル ヘルスケア リミテッド | 加湿および凝縮液管理を行うための微細構造を備える医療用部品 |
-
2016
- 2016-12-23 EP EP16206615.3A patent/EP3338835A1/en not_active Withdrawn
-
2017
- 2017-12-21 CN CN201780079197.4A patent/CN110087715B/zh active Active
- 2017-12-21 JP JP2019534089A patent/JP7305540B2/ja active Active
- 2017-12-21 EP EP17825221.9A patent/EP3558427A1/en active Pending
- 2017-12-21 WO PCT/EP2017/084143 patent/WO2018115310A1/en unknown
- 2017-12-21 US US16/471,935 patent/US11607487B2/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050154369A1 (en) * | 2002-04-05 | 2005-07-14 | Martin Broullette | Needleless syringe for the subcutaneous injection of droplets of liquid substances |
JP2006524120A (ja) * | 2003-04-21 | 2006-10-26 | ストラテージェント ライフ サイエンシズ | マイクロジェットで反復的に薬物を搬送する装置および方法 |
JP2012223562A (ja) * | 2011-04-19 | 2012-11-15 | Palo Alto Research Center Inc | コリメートされたガス流及び粒子源を用いる送達機器及び方法 |
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Publication number | Publication date |
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CN110087715A (zh) | 2019-08-02 |
CN110087715B (zh) | 2022-10-18 |
US20190307954A1 (en) | 2019-10-10 |
JP7305540B2 (ja) | 2023-07-10 |
US11607487B2 (en) | 2023-03-21 |
EP3338835A1 (en) | 2018-06-27 |
WO2018115310A1 (en) | 2018-06-28 |
EP3558427A1 (en) | 2019-10-30 |
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