JP2020151022A - Medicament inhalation tool - Google Patents
Medicament inhalation tool Download PDFInfo
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- JP2020151022A JP2020151022A JP2019050109A JP2019050109A JP2020151022A JP 2020151022 A JP2020151022 A JP 2020151022A JP 2019050109 A JP2019050109 A JP 2019050109A JP 2019050109 A JP2019050109 A JP 2019050109A JP 2020151022 A JP2020151022 A JP 2020151022A
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- drug
- mouthpiece
- opening
- chamber
- aerosol device
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- 239000003814 drug Substances 0.000 title claims abstract description 89
- 239000000443 aerosol Substances 0.000 claims abstract description 35
- 238000003825 pressing Methods 0.000 claims abstract description 18
- 229940079593 drug Drugs 0.000 claims description 76
- 230000000717 retained effect Effects 0.000 claims 1
- 238000002664 inhalation therapy Methods 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 8
- 210000000214 mouth Anatomy 0.000 description 7
- 238000004088 simulation Methods 0.000 description 5
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 230000000241 respiratory effect Effects 0.000 description 4
- 210000003128 head Anatomy 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 2
- 208000023504 respiratory system disease Diseases 0.000 description 2
- 229940126585 therapeutic drug Drugs 0.000 description 2
- 125000002066 L-histidyl group Chemical group [H]N1C([H])=NC(C([H])([H])[C@](C(=O)[*])([H])N([H])[H])=C1[H] 0.000 description 1
- 208000004350 Strabismus Diseases 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000013011 mating Effects 0.000 description 1
- 229940071648 metered dose inhaler Drugs 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Abstract
Description
本発明は、薬剤吸入器に関する。 The present invention relates to a drug inhaler.
従来から、気管支喘息治療薬やＣＯＰＤ（慢性閉塞性肺疾患）などの呼吸器疾患の治療において、加圧式定量噴霧吸入器（いわゆるエアゾール）が用いられることがあった。（例えば、特許文献１を参照）。 Conventionally, a pressurized metered dose inhaler (so-called aerosol) has been used in the treatment of respiratory diseases such as bronchial asthma therapeutic agents and COPD (chronic obstructive pulmonary disease). (See, for example, Patent Document 1).
しかしながら、従来の薬剤吸入器によると、比較的大きな操作力が必要となる場合や、薬剤吸入器の操作と吸入動作との同調が困難である場合があった。 However, according to the conventional drug inhaler, there are cases where a relatively large operating force is required, and there are cases where it is difficult to synchronize the operation of the drug inhaler with the inhalation operation.
本発明の一態様は、エアゾール器具の吐出バルブから吐出される薬剤の吐出方向を変化させるアクチュエータを保持する保持部と、前記エアゾール器具に押圧を与えて前記吐出バルブを駆動するレバー部と、前記エアゾール器具から吐出された薬剤が流入する第１開口部と、前記第１開口部から流入した薬剤が滞留するチャンバー部と、前記第１開口部への薬剤の流入方向と対向する方向成分を有する流出方向に開口し、前記チャンバー部に滞留する薬剤が流出する第２開口部とを備える薬剤吸入器である。 One aspect of the present invention includes a holding portion that holds an actuator that changes the discharge direction of the drug discharged from the discharge valve of the aerosol device, a lever portion that presses the aerosol device to drive the discharge valve, and the like. It has a first opening into which the drug discharged from the aerosol device flows in, a chamber portion in which the drug flowing in from the first opening stays, and a directional component facing the inflow direction of the drug into the first opening. A drug inhaler having a second opening that opens in the outflow direction and allows the drug staying in the chamber to flow out.
本発明の一態様に係る薬剤吸入器において、前記レバー部は、前記保持部に保持された前記エアゾール器具の底面のうち前記吐出バルブの軸線を含む位置に接して、前記エアゾール器具に押圧を与える押し当て部と、端部に配置され、利用者の操作力が加えられる操作部と、前記押し当て部の回転軌跡の回転中心として、前記吐出バルブの軸線を挟んで前記操作部とは反対側の端部に配置される支点軸とを備える。 In the drug inhaler according to one aspect of the present invention, the lever portion is in contact with a position including the axis of the discharge valve on the bottom surface of the aerosol device held by the holding portion to press the aerosol device. The pressing portion, the operating portion arranged at the end portion to which the user's operating force is applied, and the rotation center of the rotation locus of the pressing portion, opposite to the operating portion with the axis of the discharge valve interposed therebetween. It is provided with a fulcrum shaft arranged at the end of the.
本発明の一態様に係る薬剤吸入器において、前記チャンバー部の薬剤流出口に勘合する勘合部と、前記チャンバー部から前記勘合部を介して流入する薬剤が流出する前記第２開口部としての吸い口部と、前記吸い口部方向に向けられて前記吸い口部の天面に配置される上歯受け面と、前記勘合部方向に向けられ、前記吸い口部の底面の前記上歯受け面よりも前記勘合部に近い位置に配置された下歯受け面とをさらに備える。 In the drug inhaler according to one aspect of the present invention, suction as a fitting portion that fits into the drug outlet of the chamber portion and a second opening through which the drug that flows in from the chamber portion through the fitting portion flows out. The mouth portion, the upper tooth receiving surface which is directed toward the mouthpiece and is arranged on the top surface of the mouthpiece, and the upper tooth receiving surface which is directed toward the fitting portion and is located on the bottom surface of the mouthpiece. It is further provided with a lower tooth receiving surface arranged at a position closer to the fitting portion.
本発明によれば、吸入治療の難度を低減することが可能な薬剤吸入器を提供することができる。 According to the present invention, it is possible to provide a drug inhaler capable of reducing the difficulty of inhalation treatment.
[実施形態]
以下、本発明の実施形態を図面に基づいて説明する。
図１は、実施形態に係るエアゾール器具１０及び吸入器具２０の構成の一例を示す図である。本実施形態の吸入器具２０は、エアゾール器具１０から吐出される粉末状の薬剤の吸入治療を補助する。
[Embodiment]
Hereinafter, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 is a diagram showing an example of the configuration of the aerosol device 10 and the inhalation device 20 according to the embodiment. The inhalation device 20 of the present embodiment assists the inhalation treatment of the powdered drug discharged from the aerosol device 10.
[エアゾール器具１０の構成]
吸入器具２０には、エアゾール器具１０が取り付けられる。エアゾール器具１０は、薬剤ボンベ１１０と、アクチュエータ１２０とを備える。
図２は、本実施形態の薬剤ボンベ１１０の外観の一例を示す図である。薬剤ボンベ１１０は、封入されたガスの圧力によって粉末状の薬剤を吐出する。薬剤の一例としては、気管支喘息治療薬やＣＯＰＤ（慢性閉塞性肺疾患）などの呼吸器疾患の治療薬が挙げられる。本実施形態の薬剤ボンベ１１０は、その頭部に吐出バルブ１１１を備える。吐出バルブ１１１は、いわゆる定量バルブであり、薬剤ボンベ１１０の頭部１１２と底部１１３との間にバルブ軸線ＡＸ１方向の押圧が加えられると、１回の操作あたり、所定量の薬剤を吐出する。この操作は、吸入器具２０の利用者（例えば、患者）によって行われる。
[Structure of aerosol device 10]
An aerosol device 10 is attached to the inhalation device 20. The aerosol device 10 includes a drug cylinder 110 and an actuator 120.
FIG. 2 is a diagram showing an example of the appearance of the drug cylinder 110 of the present embodiment. The drug cylinder 110 discharges a powdered drug by the pressure of the enclosed gas. Examples of the drug include a therapeutic drug for bronchial asthma and a therapeutic drug for respiratory diseases such as COPD (chronic obstructive pulmonary disease). The drug cylinder 110 of the present embodiment is provided with a discharge valve 111 at its head. The discharge valve 111 is a so-called metering valve, and when a pressure is applied between the head 112 and the bottom 113 of the drug cylinder 110 in the valve axis AX1 direction, a predetermined amount of drug is discharged per operation. This operation is performed by the user (eg, patient) of the inhalation device 20.
図３は、本実施形態のアクチュエータ１２０の構成の一例を示す図である。アクチュエータ１２０は、薬剤ボンベ１１０の頭部１１２に取り付けられる。アクチュエータ１２０は、薬剤ボンベ１１０に取り付けられた状態で利用者の操作による押圧Ｆ１が加えられると、加えられた押圧を吐出バルブ１１１に伝達する。吐出バルブ１１１は、アクチュエータ１２０を介して伝達された押圧により駆動され、所定量の薬剤をバルブ軸線ＡＸ１方向に吐出する。
アクチュエータ１２０は、エアゾール器具１０の吐出バルブ１１１から吐出される薬剤の吐出方向Ｄ１を変化させる。一例として、アクチュエータ１２０は、バルブ軸線ＡＸ１方向に吐出された薬剤の移動方向をバルブ軸線ＡＸ１とは異なる方向（例えば、吐出軸線ＡＸ２の方向）に変化させる。この一例において、バルブ軸線ＡＸ１と、吐出軸線ＡＸ２とのなす角θは９０°〜１２０°であることが好ましく、１０５°であることがより好ましい。
FIG. 3 is a diagram showing an example of the configuration of the actuator 120 of the present embodiment. The actuator 120 is attached to the head 112 of the drug cylinder 110. When the pressing force F1 operated by the user is applied while the actuator 120 is attached to the drug cylinder 110, the applied pressing force is transmitted to the discharge valve 111. The discharge valve 111 is driven by the pressing transmitted via the actuator 120, and discharges a predetermined amount of the drug in the valve axis AX1 direction.
The actuator 120 changes the discharge direction D1 of the drug discharged from the discharge valve 111 of the aerosol device 10. As an example, the actuator 120 changes the moving direction of the medicine discharged in the direction of the valve axis AX1 to a direction different from that of the valve axis AX1 (for example, the direction of the discharge axis AX2). In this example, the angle θ formed by the valve axis AX1 and the discharge axis AX2 is preferably 90 ° to 120 °, more preferably 105 °.
[吸入器具２０の構成]
図１に戻り、吸入器具２０は、本体２１０と、レバー２２０と、チャンバー２３０と、吸い口２４０とを備える。
レバー２２０は、エアゾール器具１０に押圧Ｆ１を与えて吐出バルブ１１１を駆動する。
[Structure of inhalation device 20]
Returning to FIG. 1, the inhalation device 20 includes a main body 210, a lever 220, a chamber 230, and a suction port 240.
The lever 220 applies a pressing F1 to the aerosol device 10 to drive the discharge valve 111.
より具体的には、レバー２２０は、支点軸２２１と、押し当て部２２２と、操作部２２３とを備える。
操作部２２３は、端部に配置され、利用者の操作力が加えられる。
押し当て部２２２は、保持部２１１に保持されたエアゾール器具１０の底面のうち吐出バルブ１１１の軸線（バルブ軸線ＡＸ１）を含む位置に接して、エアゾール器具１０に押圧Ｆ１を与える。
支点軸２２１は、押し当て部２２２の回転軌跡の回転中心として、吐出バルブ１１１のバルブ軸線ＡＸ１を挟んで操作部２２３とは反対側の端部に配置される。
つまりレバー２２０は、支点である支点軸２２１、作用点である押し当て部２２２、及び力点である操作部２２３がこの記載順に配置された梃装置である。吸入器具２０は、レバー２２０を備えることにより、エアゾール器具１０単体の場合に比べてより小さな操作力によって薬剤ボンベ１１０に押圧Ｆ１を与えることができる。
More specifically, the lever 220 includes a fulcrum shaft 221, a pressing portion 222, and an operating portion 223.
The operation unit 223 is arranged at the end portion, and the operation force of the user is applied.
The pressing portion 222 is in contact with a position including the axis (valve axis AX1) of the discharge valve 111 on the bottom surface of the aerosol instrument 10 held by the holding portion 211, and applies the pressing F1 to the aerosol instrument 10.
The fulcrum shaft 221 is arranged at the end of the discharge valve 111 on the opposite side of the valve axis AX1 as the rotation center of the rotation locus of the pressing portion 222.
That is, the lever 220 is a lever device in which a fulcrum shaft 221 as a fulcrum, a pressing portion 222 as an action point, and an operation portion 223 as a force point are arranged in the order described. By providing the lever 220, the inhalation device 20 can apply the pressing F1 to the drug cylinder 110 with a smaller operating force than in the case of the aerosol device 10 alone.
本体２１０は、保持部２１１と、第１開口部２１２と、第２開口部２４１とを備える。
保持部２１１は、アクチュエータ１２０を保持する。第１開口部２１２は、保持部２１１に保持されたアクチュエータ１２０が薬剤を吐出する方向（吐出方向Ｄ１、例えば、吐出軸線ＡＸ２の方向）に開口している。第１開口部２１２には、エアゾール器具１０から吐出された薬剤が流入する。
The main body 210 includes a holding portion 211, a first opening 212, and a second opening 241.
The holding unit 211 holds the actuator 120. The first opening 212 is opened in the direction in which the actuator 120 held by the holding portion 211 discharges the drug (discharge direction D1, for example, the direction of the discharge axis AX2). The drug discharged from the aerosol device 10 flows into the first opening 212.
チャンバー２３０は、第１開口部２１２から流入した薬剤が滞留する。チャンバー２３０の内容積は、５０ｃｃ〜１００ｃｃ程度であることが好ましい。
吸い口２４０は、利用者の口に咥えられる。第２開口部２４１は、吸い口２４０の端部において、第１開口部２１２への薬剤の流入方向（つまり、吐出方向Ｄ１）と対向する方向成分を有する流出方向（つまり、吸い出し方向Ｄ２）に開口し、チャンバー２３０に滞留する薬剤が流出する。
In the chamber 230, the drug flowing in from the first opening 212 stays. The internal volume of the chamber 230 is preferably about 50 cc to 100 cc.
The mouthpiece 240 is held in the mouth of the user. The second opening 241 is in the outflow direction (that is, the suction direction D2) having a direction component facing the inflow direction (that is, the discharge direction D1) of the drug into the first opening 212 at the end of the mouthpiece 240. The drug that opens and stays in the chamber 230 flows out.
なお、吸入器具２０は、チャンバー２３０から吸い口２４０方向に流出する薬剤が再びチャンバー２３０内に戻らないようにする逆止弁２４２を備えていてもよい。 The inhalation device 20 may include a check valve 242 that prevents the drug flowing out of the chamber 230 in the direction of the mouthpiece 240 from returning to the chamber 230.
本実施形態の一例では、吸い口２４０は本体２１０の一部として構成され、本体２１０と一体成型（又は本体２１０と吸い口２４０とが着脱不可能に接合）されている。
なお、吸い口２４０は、本体２１０とは別体のマウスピース２５０として構成されていてもよい。この場合、マウスピース２５０は、本体２１０への取り付け及び本体２１０からの取り外しが可能であり、洗浄を容易にする。
以下、このマウスピース２５０の形状の一例について説明する。なお、本体２１０と一体化されている吸い口２４０の形状も、以下説明するマウスピース２５０の形状と同様の形状であってよい。
In one example of this embodiment, the mouthpiece 240 is configured as a part of the main body 210, and is integrally molded with the main body 210 (or the main body 210 and the mouthpiece 240 are non-detachably joined).
The mouthpiece 240 may be configured as a mouthpiece 250 that is separate from the main body 210. In this case, the mouthpiece 250 can be attached to and removed from the main body 210, facilitating cleaning.
Hereinafter, an example of the shape of the mouthpiece 250 will be described. The shape of the mouthpiece 240 integrated with the main body 210 may be the same as the shape of the mouthpiece 250 described below.
図４は、本実施形態のマウスピース２５０の外観側面の一例を示す図である。図５は、本実施形態のマウスピース２５０の外観天面の一例を示す図である。
マウスピース２５０は、利用者の口に咥えられる。マウスピース２５０は、勘合部２５１と、吐出部２５２と、上歯受け面２５３と、下歯受け面２５４と、舌当て面２５５とを備える。
FIG. 4 is a diagram showing an example of the appearance side surface of the mouthpiece 250 of the present embodiment. FIG. 5 is a diagram showing an example of the external top surface of the mouthpiece 250 of the present embodiment.
The mouthpiece 250 is held in the user's mouth. The mouthpiece 250 includes a fitting portion 251, a discharge portion 252, an upper tooth receiving surface 253, a lower tooth receiving surface 254, and a tongue contact surface 255.
勘合部２５１は、チャンバー２３０の薬剤流出口に勘合する。勘合部２５１からは、チャンバー２３０から薬剤がマウスピース２５０内に流入する。
吐出部２５２は、チャンバー２３０から勘合部２５１を介して流入する薬剤が、利用者の口腔内に流出する開口部である。この一例の構成の場合、上述した第２開口部２４１が吸い口２４０に相当する。吐出部２５２は、マウスピース２５０の天面側と底面側との長さの差が長さＬｅとなるテーパー形状とされていてもよい。吐出部２５２がテーパー形状にされることにより、テーパー形状でない場合に比べて薬剤がより効率的に利用者の呼吸器官に到達する。
The fitting portion 251 fits into the drug outlet of the chamber 230. From the fitting portion 251 the drug flows into the mouthpiece 250 from the chamber 230.
The discharge portion 252 is an opening through which the drug flowing from the chamber 230 through the fitting portion 251 flows out into the oral cavity of the user. In the case of this example configuration, the above-mentioned second opening 241 corresponds to the mouthpiece 240. The discharge portion 252 may have a tapered shape in which the difference in length between the top surface side and the bottom surface side of the mouthpiece 250 is the length Le. Since the discharge portion 252 has a tapered shape, the drug reaches the user's respiratory organs more efficiently than when the discharge portion 252 has a tapered shape.
上歯受け面２５３は、勘合部２５１と吸い口２４０とのうち、吸い口２４０の方向に向けられて、マウスピース２５０の天面に配置される。利用者がマウスピース２５０を咥えた状態において、上歯受け面２５３には、利用者の上顎の前歯（以下の説明において上歯ともいう。）の表面（口腔外側の面）が接する。上歯受け面２５３は、ｚ方向の長さＬｃが１〜４ｍｍ程度、より好ましくは２ｍｍ程度とされる。
なお、マウスピース２５０は、上歯受け溝２５３１を備えていてもよい。この場合、上歯受け溝２５３１の吸い口２４０方向に向けられた面が、上歯受け面２５３として構成されていてもよい。
上歯受け面２５３は、図５に示す天面視においてマウスピース２５０のｙ方向（幅方向）の長さよりも、狭い幅であってよい。つまり、上歯受け面２５３の幅（長さＬｈ）＜マウスピース２５０の幅（長さＬｆ）と構成されていてもよい。これらの幅の比を、長さＬｈ：長さＬｆとして表した場合、長さＬｈ：長さＬｆが１：１〜１：３程度であってよい。換言すれば、長さＬｈは、長さＬｆの３分の１以上であってよい。
The upper tooth receiving surface 253 is arranged on the top surface of the mouthpiece 250 so as to face the direction of the mouthpiece 240 of the fitting portion 251 and the mouthpiece 240. In a state where the user holds the mouthpiece 250, the upper tooth receiving surface 253 is in contact with the surface (outer oral surface) of the anterior teeth of the user's upper jaw (also referred to as upper teeth in the following description). The upper tooth receiving surface 253 has a length Lc in the z direction of about 1 to 4 mm, more preferably about 2 mm.
The mouthpiece 250 may include an upper tooth receiving groove 2531. In this case, the surface of the upper tooth receiving groove 2531 facing the suction port 240 direction may be configured as the upper tooth receiving surface 253.
The upper tooth receiving surface 253 may have a width narrower than the length in the y direction (width direction) of the mouthpiece 250 in the top view shown in FIG. That is, the width (length Lh) of the upper tooth receiving surface 253 may be less than the width (length Lf) of the mouthpiece 250. When the ratio of these widths is expressed as length Lh: length Lf, the length Lh: length Lf may be about 1: 1 to 1: 3. In other words, the length Lh may be one-third or more of the length Lf.
下歯受け面２５４は、勘合部２５１と吸い口２４０とのうち、勘合部２５１の方向に向けられて、マウスピース２５０の底面に配置される。利用者がマウスピース２５０を咥えた状態において、下歯受け面２５４には、利用者の下顎の前歯（以下の説明において下歯ともいう。）の裏面（口腔内側の面）が接する。下歯受け面２５４は、ｚ方向の長さＬｄが１〜４ｍｍ程度、より好ましくは２ｍｍとされる。下歯受け面２５４は、上歯受け面２５３よりもｘ軸の負の方向に長さＬｂずれた位置に配置される。長さＬｂは、１〜１０ｍｍ程度、より好ましくは５ｍｍ程度とされる。
なお、マウスピース２５０は、下歯受け溝２５４１を備えていてもよい。この場合、下歯受け溝２５４１の勘合部２５１方向に向けられた面が、下歯受け面２５４として構成されていてもよい。
The lower tooth receiving surface 254 is arranged on the bottom surface of the mouthpiece 250 so as to face the fitting portion 251 of the fitting portion 251 and the suction port 240. In the state where the user holds the mouthpiece 250, the lower tooth receiving surface 254 is in contact with the back surface (inner surface of the oral cavity) of the anterior teeth of the user's lower jaw (also referred to as the lower teeth in the following description). The lower tooth receiving surface 254 has a length Ld in the z direction of about 1 to 4 mm, more preferably 2 mm. The lower tooth receiving surface 254 is arranged at a position deviated by a length Lb in the negative direction of the x-axis from the upper tooth receiving surface 253. The length Lb is about 1 to 10 mm, more preferably about 5 mm.
The mouthpiece 250 may include a lower tooth receiving groove 2541. In this case, the surface of the lower tooth receiving groove 2541 facing in the mating portion 251 direction may be configured as the lower tooth receiving surface 254.
舌当て面２５５は、マウスピース２５０の底面に、ｘ方向（奥行方向）の長さＬａにして配置される。長さＬａは、３０ｍｍ〜５０ｍｍ程度、より好ましくは４０ｍｍ程度とされる。この舌当て面２５５は、マウスピース２５０が利用者の口に咥えられた場合に、利用者の舌をｚ軸の負方向に押圧する。舌当て面２５５が、利用者の舌を押圧することにより、利用者の舌が薬剤の吸引の妨げになることを抑止できる。このように構成されたマウスピース２５０によれば、薬剤がより効率的に利用者の呼吸器官に到達させることができる。 The tongue pad surface 255 is arranged on the bottom surface of the mouthpiece 250 with a length La in the x direction (depth direction). The length La is about 30 mm to 50 mm, more preferably about 40 mm. The tongue pad surface 255 presses the user's tongue in the negative direction of the z-axis when the mouthpiece 250 is held in the user's mouth. By pressing the user's tongue with the tongue pad surface 255, it is possible to prevent the user's tongue from interfering with the suction of the drug. According to the mouthpiece 250 configured in this way, the drug can reach the user's respiratory organs more efficiently.
[吸入時の薬剤の流れ]
図６から図９を参照して、吸入時の吸入器具２０の内部の薬剤の流れについて説明する。
図６は、本実施形態の吸入器具２０の内部の薬剤の流れの一例を示す図である。図７〜図９は、本実施形態の薬剤の流れのシミュレーション結果の一例を示す図である。
[Drug flow during inhalation]
The flow of the drug inside the inhalation device 20 at the time of inhalation will be described with reference to FIGS. 6 to 9.
FIG. 6 is a diagram showing an example of the flow of the drug inside the inhalation device 20 of the present embodiment. 7 to 9 are diagrams showing an example of the simulation result of the flow of the drug of the present embodiment.
アクチュエータ１２０から吐出軸線ＡＸ２方向に吐出された薬剤は、チャンバー２３０の内部でｚ軸の負方向（チャンバー２３０の底部の方向）に流れる。さらに、薬剤は、チャンバー２３０の内壁に沿ってｚ軸の正の方向（同図中の方向Ｄ３）、ｘ軸の正の方向（同図中の吸い出し方向Ｄ２）と方向を変化させつつ、第２開口部２４１に到達する。図７〜図９には、薬剤の流れのシミュレーション結果の一例を示す。 The drug discharged from the actuator 120 in the discharge axis AX2 direction flows inside the chamber 230 in the negative direction of the z-axis (direction of the bottom of the chamber 230). Further, the agent changes its direction along the inner wall of the chamber 230 in the positive direction of the z-axis (direction D3 in the figure) and the positive direction of the x-axis (suction direction D2 in the figure). 2 Reach the opening 241. 7 to 9 show an example of the simulation result of the flow of the drug.
これらの図に示したように、本実施形態の吸入器具２０は、チャンバー２３０内において薬剤が攪拌される。このため、利用者が、吸入器具２０を利用せずにアクチュエータ１２０から吐出される薬剤を直接吸入する場合に比べて、薬剤の濃度が均一化され、より効率的に利用者の呼吸器官に到達する。 As shown in these figures, in the inhalation device 20 of the present embodiment, the drug is agitated in the chamber 230. Therefore, as compared with the case where the user directly inhales the drug discharged from the actuator 120 without using the inhalation device 20, the concentration of the drug is made uniform and reaches the user's respiratory organs more efficiently. To do.
また、従来において、利用者が吸入器具２０を利用せずにアクチュエータ１２０から吐出される薬剤を直接吸入する場合には、エアゾール器具１０の操作タイミングと、吸入動作（例えば、深呼吸）のタイミングとを一致させる必要があり、吸入治療の難度が高くなってしまうという場合があった。例えば、エアゾール器具１０の操作タイミングに比べて、吸入動作のタイミングが遅れたような場合には、吐出された薬剤が吸入される前に空気中に拡散してしまい、治療に必要な量の薬剤を吸入することができないというような場合があった。 Further, conventionally, when the user directly inhales the drug discharged from the actuator 120 without using the inhalation device 20, the operation timing of the aerosol device 10 and the timing of the inhalation operation (for example, deep breathing) are set. In some cases, it was necessary to match and the difficulty of inhalation treatment became high. For example, if the timing of the inhalation operation is delayed compared to the operation timing of the aerosol device 10, the discharged drug diffuses into the air before being inhaled, and the amount of the drug required for treatment In some cases, it was not possible to inhale.
本実施形態の吸入器具２０は、チャンバー２３０の内容積によって、薬剤がチャンバー２３０内に滞留する。このため、エアゾール器具１０の操作タイミングに比べて、吸入動作のタイミングが遅れたような場合であっても、チャンバー２３０内に滞留している薬剤を吸引することができる。したがって、本実施形態の吸入器具２０によれば、吸入治療の難度を低減することができる。 In the inhalation device 20 of the present embodiment, the drug stays in the chamber 230 due to the internal volume of the chamber 230. Therefore, even if the timing of the suction operation is delayed compared to the operation timing of the aerosol device 10, the drug staying in the chamber 230 can be sucked. Therefore, according to the inhalation device 20 of the present embodiment, the difficulty of inhalation treatment can be reduced.
図１０は、本実施形態の吸入器具２０の利用中の状態の一例を示す図である。本実施形態の吸入器具２０は、容積の大きなチャンバー２３０が利用者の掌中に収まる形状を有している。このように構成された吸入器具２０によれば、比較的小さな握力で操作することを可能にし、利用者にとって取扱いやすくするとともに、利用者が吸入器具２０を掌で隠せるため、吸入動作を第三者の目につきにくくさせることができる。吸入治療は利用者自らが所定のタイミングで行うことが求められる場合がある。例えば、外出先や交通機関による移動中などにおいて吸入治療を行う必要がある場合において、吸入動作が第三者の目につきやすいと、利用者によっては吸入治療をためらってしまう場合が生じる。本実施形態の吸入器具２０によれば、吸入動作を第三者の目につきにくくさせることができるため、利用者は、より適切なタイミングでためらいなく吸入動作を行うことができ、効果的な吸入治療を可能にすることができる。 FIG. 10 is a diagram showing an example of a state in which the inhalation device 20 of the present embodiment is in use. The inhalation device 20 of the present embodiment has a shape in which the chamber 230 having a large volume fits in the palm of the user. According to the inhalation device 20 configured in this way, it is possible to operate with a relatively small grip force, it is easy for the user to handle, and the user can hide the inhalation device 20 with his / her palm. It can be made difficult for people to see. Inhalation treatment may be required to be performed by the user himself / herself at a predetermined timing. For example, when it is necessary to perform inhalation treatment while on the go or while traveling by transportation, if the inhalation operation is easily noticed by a third party, some users may hesitate to perform inhalation treatment. According to the inhalation device 20 of the present embodiment, the inhalation operation can be made invisible to a third party, so that the user can perform the inhalation operation at a more appropriate timing without hesitation, and effective inhalation. Treatment can be made possible.
また、本実施形態の吸入器具２０は、エアゾール器具１０の薬剤ボンベ１１０とアクチュエータ１２０とを結合したままの状態で、エアゾール器具１０を保持することができる。ここで、エアゾール器具１０は、吐出バルブ１１１の形状等に基づいてアクチュエータ１２０の形状が設計されている場合があり、薬剤ボンベ１１０とアクチュエータ１２０とを分離して、薬剤ボンベ１１０から直接的に薬剤を吐出させるとすると、薬剤の吐出方向が安定しない場合がある。本実施形態の吸入器具２０は、エアゾール器具１０の薬剤ボンベ１１０とアクチュエータ１２０とを結合したままの状態でエアゾール器具１０を保持するため、薬剤ボンベ１１０薬剤の吐出方向が安定し、薬剤をより効率的に利用者の呼吸器に到達させることができる。 Further, the inhalation device 20 of the present embodiment can hold the aerosol device 10 in a state where the drug cylinder 110 of the aerosol device 10 and the actuator 120 are still connected. Here, in the aerosol device 10, the shape of the actuator 120 may be designed based on the shape of the discharge valve 111 or the like, and the drug cylinder 110 and the actuator 120 are separated from each other and the drug is directly discharged from the drug cylinder 110. However, the discharge direction of the drug may not be stable. Since the inhalation device 20 of the present embodiment holds the aerosol device 10 in a state where the drug cylinder 110 of the aerosol device 10 and the actuator 120 are still connected, the discharge direction of the drug cylinder 110 drug is stable and the drug is more efficient. Can reach the user's respiratory organs.
その他、本発明の趣旨を逸脱しない範囲で、上記した実施の形態における構成要素を周知の構成要素に置き換えることは適宜可能である。 In addition, it is possible to replace the components in the above-described embodiment with well-known components as appropriate without departing from the spirit of the present invention.
１０…エアゾール器具、１１０…薬剤ボンベ、１１１…吐出バルブ、１２０…アクチュエータ、２０…吸入器具、２１０…本体、２１１…保持部、２１２…第１開口部、２２０…レバー、２２１…支点軸、２２２…押し当て部、２２３…操作部、２３０…チャンバー、２４０…吸い口、２４１…第２開口部、２４２…逆止弁、２５０…マウスピース、２５１…勘合部、２５２…吐出部、２５３…上歯受け面、２５３１…上歯受け溝、２５４…下歯受け面、２５４１…下歯受け溝、２５５…舌当て面 10 ... Aerosol device, 110 ... Drug cylinder, 111 ... Discharge valve, 120 ... Actuator, 20 ... Suction device, 210 ... Main body, 211 ... Holding part, 212 ... First opening, 220 ... Lever, 221 ... Mouth shaft, 222 ... Pressing part, 223 ... Operation part, 230 ... Chamber, 240 ... Suction port, 241 ... Second opening, 242 ... Check valve, 250 ... Mouthpiece, 251 ... Fitting part, 252 ... Discharge part, 253 ... Above Tooth receiving surface, 2531 ... Upper tooth receiving groove, 254 ... Lower tooth receiving surface, 2541 ... Lower tooth receiving groove, 255 ... Tongue pad surface
Claims (3)
前記エアゾール器具に押圧を与えて前記吐出バルブを駆動するレバー部と、
前記エアゾール器具から吐出された薬剤が流入する第１開口部と、
前記第１開口部から流入した薬剤が滞留するチャンバー部と、
前記第１開口部への薬剤の流入方向と対向する方向成分を有する流出方向に開口し、前記チャンバー部に滞留する薬剤が流出する第２開口部と
を備える薬剤吸入器。 A holding unit that holds an actuator that changes the discharge direction of the drug discharged from the discharge valve of the aerosol device,
A lever portion that drives the discharge valve by applying pressure to the aerosol device, and
The first opening into which the drug discharged from the aerosol device flows in, and
A chamber portion in which the drug flowing in from the first opening is retained, and a chamber portion.
A drug inhaler having a second opening that opens in an outflow direction having a component in a direction opposite to the inflow direction of the drug into the first opening and outflows the drug that stays in the chamber.
前記保持部に保持された前記エアゾール器具の底面のうち前記吐出バルブの軸線を含む位置に接して、前記エアゾール器具に押圧を与える押し当て部と、
端部に配置され、利用者の操作力が加えられる操作部と、
前記押し当て部の回転軌跡の回転中心として、前記吐出バルブの軸線を挟んで前記操作部とは反対側の端部に配置される支点軸と、
を備える請求項１に記載の薬剤吸入器。 The lever part
A pressing portion that is in contact with the bottom surface of the aerosol device held by the holding portion and includes the axis of the discharge valve to press the aerosol device.
An operation unit that is placed at the end and where the user's operation force is applied,
As the rotation center of the rotation locus of the pressing portion, a fulcrum shaft arranged at an end portion opposite to the operation portion across the axis of the discharge valve, and
The drug inhaler according to claim 1.
前記チャンバー部から前記勘合部を介して流入する薬剤が流出する前記第２開口部としての吸い口部と、
前記吸い口部方向に向けられて前記吸い口部の天面に配置される上歯受け面と、
前記勘合部方向に向けられ、前記吸い口部の底面の前記上歯受け面よりも前記勘合部に近い位置に配置された下歯受け面と、
をさらに備える請求項１又は請求項２に記載の薬剤吸入器。 A fitting part that fits into the drug outlet of the chamber part and
A mouthpiece portion as the second opening through which the drug flowing in from the chamber portion through the fitting portion flows out,
An upper tooth receiving surface that is directed toward the mouthpiece and is arranged on the top surface of the mouthpiece.
A lower tooth receiving surface that is directed toward the fitting portion and is arranged at a position closer to the fitting portion than the upper tooth receiving surface on the bottom surface of the mouthpiece portion.
The drug inhaler according to claim 1 or 2, further comprising.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024005386A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005384A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005385A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005389A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4940051A (en) * | 1983-12-28 | 1990-07-10 | Huhtamki Oy | Inhalation device |
| US5598836A (en) * | 1995-05-26 | 1997-02-04 | Healthscan Products, Inc. | Metered dose inhalation unit with slide means |
| JP2009072563A (en) * | 2007-08-30 | 2009-04-09 | Univ Nihon | Inhalator attachment |
| JP2011098224A (en) * | 1997-10-17 | 2011-05-19 | Systemic Pulmonary Delivery Ltd | Method and apparatus for delivering aerosolized medication |
| JP2012513233A (en) * | 2008-12-23 | 2012-06-14 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Method for aerosol drug delivery and device comprising a mouthpiece having a step structure |
| US20140318534A1 (en) * | 2013-03-14 | 2014-10-30 | Trudell Medical International | Metered dose inhaler applicator |
-
2019
- 2019-03-18 JP JP2019050109A patent/JP7250317B2/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4940051A (en) * | 1983-12-28 | 1990-07-10 | Huhtamki Oy | Inhalation device |
| US5598836A (en) * | 1995-05-26 | 1997-02-04 | Healthscan Products, Inc. | Metered dose inhalation unit with slide means |
| JP2011098224A (en) * | 1997-10-17 | 2011-05-19 | Systemic Pulmonary Delivery Ltd | Method and apparatus for delivering aerosolized medication |
| JP2009072563A (en) * | 2007-08-30 | 2009-04-09 | Univ Nihon | Inhalator attachment |
| JP2012513233A (en) * | 2008-12-23 | 2012-06-14 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | Method for aerosol drug delivery and device comprising a mouthpiece having a step structure |
| US20140318534A1 (en) * | 2013-03-14 | 2014-10-30 | Trudell Medical International | Metered dose inhaler applicator |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024005386A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005384A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005385A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
| WO2024005389A1 (en) * | 2022-07-01 | 2024-01-04 | 주식회사 케이티앤지 | Inhaler |
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|---|---|
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