JP2020103621A - Medical agent-holding molded body, syringe, and medical agent holding container - Google Patents

Abstract

To provide a medical material for suppressing increase of an environmental load.SOLUTION: Technology is present in which nanofibers are collected from natural materials and used as high functional materials. A medical agent-holding molded body of the present invention has an exterior body for holding a medical agent inside. The medical agent-holding molded body is provided in which the exterior body is formed by materials containing natural polymer-based nanofibers. The natural polymer-based nanofibers are superior in heat resistance and chemical resistance, and therefore the medical agent-holding molded body using the natural polymer-based nanofibers can be used repeatedly by cleaning and sterilizing. Also, even if being disposed immediately after use, an environmental load can be reduced more than the use of a molded body derived from petroleum.SELECTED DRAWING: Figure 1

Description

The present invention relates to a drug holding molded body, a syringe, and a drug holding container.

In the medical industry, many disposable medical materials such as syringes and drug holding containers are used.

Note that Patent Document 1 discloses a technique related to a safety syringe. In paragraph [0005] of the same document, "After the injection is completed, the conical rods on the elastic piston engage with the conical holes on the needle tube set, and the elastic piston is pulled by an external force to pull the needle tube set into the syringe barrel. It is retracted into the body and stored inside the syringe barrel.In addition, a protrusion is further formed on the adapter of the needle tube set, and this protrusion automatically occurs when the needle tube set is retracted into the syringe barrel. It is possible to prevent the needle tube from being inadvertently exposed to the outside of the syringe barrel again by inclining it and bringing it into contact with the inner wall of the syringe barrel.”

JP, 2001-37878, A

Most of disposable medical materials such as syringes and drug holding containers are made of petroleum-derived plastics, which not only contributes to the increase of CO ₂ emission, but also are hard to be decomposed in the natural world and increase the environmental load. Is invited.

The present invention has been made in view of the above points, and an object thereof is to provide a medical material that suppresses an increase in environmental load.

The present application includes a plurality of means for solving at least a part of the above problems, and examples thereof are as follows.

In order to solve the above problems, a drug-holding molded body according to an aspect of the present invention has an exterior body that holds a drug therein, and the exterior body is formed of a material containing a natural polymer nanofiber. Has been done.

Further, in order to solve the above problems, a syringe according to another aspect of the present invention is configured by the above-mentioned drug-holding molded body, and has the exterior body as a syringe.

Moreover, in order to solve the said subject, the chemical|medical agent holding container which concerns on another aspect of this invention is comprised by the above-mentioned chemical|medical agent holding molded object.

According to the present invention, it is possible to provide a medical material that suppresses an increase in environmental load.

Problems, configurations, and effects other than those described above will be clarified by the following description of the embodiments.

It is a figure which shows an example of the external appearance of the chemical|medical agent retention molded object in 1st Embodiment. It is a figure which shows an example of the functional block of the chemical|medical agent retention molded object in 1st Embodiment. It is a sequence diagram which shows an example of a process of the chemical|medical agent retention molded object display system in 1st Embodiment. It is a figure which shows an example of the functional block of the chemical|medical agent retention molded object in the modification of 1st Embodiment. It is a sequence diagram which shows an example of a process of the chemical|medical agent retention molded object display system in the modification of 1st Embodiment. It is a figure which shows an example of the external appearance of the chemical|medical agent retention molded object in 2nd Embodiment.

There is a technology in which nanofibers are extracted from natural materials and used as high-performance materials. For example, cellulose nanofibers obtained by chemically or physically defibrating pulp and paper for papermaking, and chitin nanofibers obtained by refining and defibrating chitin contained in crab shells and the like, It is used as a natural polymer nanofiber (or bio-based nanofiber).

The nanofiber refers to a fiber material having a fiber diameter of 1 nm or more and 100 nm or less. As an example, a slurry of cellulose nanofibers obtained in the defibration process of pulp or wood for papermaking, or a dispersion obtained by dispersing dried cellulose nanofibers in a liquid is compounded with a resin and applied onto a substrate. Then, a film-shaped molded article of cellulose nanofibers can be obtained. In addition, a three-dimensional molded body of cellulose nanofibers can be obtained by three-dimensionally molding the slurry or dispersion.

The molded product of cellulose nanofibers thus produced has excellent properties such as light weight, high strength, small thermal expansion and high transparency due to the action of crystallization of the cellulose molecular chain. Moreover, since cellulose nanofibers are derived from plants, the environmental load related to production and disposal is small.

Therefore, cellulose nanofibers are expected to be applied in various fields such as structural materials such as filters and electronic materials such as electronic devices. The drug holding molded body according to the present embodiment is configured to contain a natural polymer nanofiber. Hereinafter, description will be given using an example in which the drug-holding molded body is formed of a material containing cellulose nanofibers.

Since the cellulose nanofibers have excellent heat resistance and chemical resistance, the drug-holding molded product using the cellulose nanofibers can be repeatedly used by washing and sterilizing. Further, even when it is discarded immediately after use, since it is derived from plants, it is possible to reduce the environmental load as compared with the case where a molded product derived from petroleum is used.

<First Embodiment>

Hereinafter, an example of an embodiment of the present invention will be described with reference to the drawings. The first embodiment relates to a syringe produced by using the drug holding molded body 1.

FIG. 1 is a diagram showing an example of an external appearance of a drug holding molded body 1 according to the first embodiment. The drug-holding molded body 1 is a syringe, and includes a syringe 10, which is an exterior body that holds a drug therein, a barrel tip 11, a needle 12, a finger flange 13, a plunger 14, and an electronic component 15. Have. The syringe 10 and the finger flange 13 are formed of a material containing cellulose nanofibers.

As an example, the syringe 10 and the finger flange 13 are produced by integrally molding using a dispersion liquid in which cellulose nanofibers are dispersed. The method of generating the syringe 10 and the finger flange 13 is not limited to this. For example, the syringe 10 and the finger flange 13 may be formed by molding cellulose nanofibers into a sheet and welding or adhering necessary portions.

The barrel tip 11 is a member that guides the drug held in the syringe 10 to the needle 12. The needle 12 guides the drug solution into the body. The material of the barrel tip 11 and the needle 12 is not limited, but as an example, the barrel tip 11 and the needle 12 are formed of a material containing cellulose nanofibers. The syringe in the present embodiment does not have to have the needle 12, and may be one that injects air to inject the drug solution into the body, for example.

The plunger 14 is a member that has a pusher that is pressed by the practitioner at one end and a gasket that is at the other end, and the drug in the syringe 10 is injected into the body by pressing the pusher. The material of the plunger 14 is not limited, but as an example, it is formed of a material containing cellulose nanofibers.

The syringe 10 made of a material containing cellulose nanofibers is, for example, transparent. The syringe 10 may be colorless transparent, colored transparent, or colored opaque. Human error can be suppressed by color-coding according to the application. When the barrel tip 11, the needle 12, or the plunger 14 is made of a material containing cellulose nanofibers, it may be transparent. As a matter of course, the tip 11, the needle 12, or the plunger 14 can also be color-coded according to the application.

The electronic component 15 includes a display unit 151, a power supply unit 152, and a communication unit 153. The display unit 151 is a display device such as a liquid crystal display or an organic EL display, which is installed in the syringe 10 that is an exterior body. The display unit 151 displays information received from another device connected via the communication unit 153, for example.

Further, for example, the display unit 151 is configured to contain cellulose nanofiber. The display device constituting the display unit 151 is produced by using a transparent substrate obtained by immersing a sheet obtained by filtering a dispersion liquid of cellulosic nanofibers in a resin and curing the sheet. As an example, the display unit 151 is generated by stacking a transparent electrode such as ITO (indium tin oxide) or a metal nanowire, and an organic electroluminescence layer or a liquid crystal layer containing a light emitting material on a transparent substrate containing cellulose nanofibers. To be done.

As an example, the display unit 151 is transparent when no display is being performed. The display unit 151 may be non-colored transparent, colored transparent, or colored opaque. By configuring the display unit 151 with different colors depending on the application, it is possible to prevent mistakes such as mixing up of medicines.

The display unit 151 displays by using electricity supplied from the power supply unit 152 as power. The display unit 151 produced by containing the cellulose nanofibers is excellent in flexibility and can change its shape according to the shape of the exterior body. The display unit 151 may be composed of a display device used in a general electronic device.

The power supply unit 152 supplies electricity to each unit (the display unit 151, the communication unit 153, and the control unit 110 described below) that configures the electronic component 15. For example, the power supply unit 152 is installed on the exterior body and is configured by a solar cell containing cellulose nanofibers. In that case, the power supply unit 152 is generated by printing a metal nanowire or laminating a metal thin film on a transparent substrate including cellulose nanofibers and mounting a solar cell element. That is, the solar cell element functions as a power generation layer. Further, in this case, the power supply unit 152 functions as a power generation unit. A solar cell using cellulose nanofibers is as flexible as a display device, and its shape can be changed according to the shape of the outer package. The power supply unit 152 may be composed of a small battery used in a general electronic device.

The communication unit 153 connects to another device (a terminal device 200 described later) by wire or wirelessly to send and receive information. For example, the communication unit 153 is installed on the exterior body and includes an antenna containing cellulose nanofibers. In that case, the communication unit 153 is generated, for example, by printing metal nanowires or laminating metal thin films on a transparent substrate including cellulose nanofibers. An antenna using cellulose nanofibers is as flexible as a display device, and its shape can be changed according to the shape of the exterior body. The communication unit 153 may be configured with an antenna used in a general electronic device. Further, the communication unit 153 may be transparent.

When the substrate included in the electronic component 15 is made of cellulose nanofiber, the substrate may be a part of the syringe 10. That is, for example, the display unit 151 may be configured by stacking the transparent electrode and the organic electroluminescence layer or the liquid crystal layer on the syringe 10 that is the outer package. Similarly, the power supply unit 152 and the communication unit 153 may also be configured by installing various components on the syringe 10 that is an exterior body.

Further, at least a part of the electronic component 15 may be attachable to and detachable from the exterior body 10. The electronic component 15 may have an electronic tag such as an RFID (radio frequency identifier) in addition to the display unit 151, the power supply unit 152, and the communication unit 153. For example, identification information for identifying a drug is readablely recorded on an electronic tag. By reading the electronic tag of the electronic component 15 with a tag reader connected to the terminal device 200 or the like, management efficiency such as inventory management of medicines is improved.

In addition, the drug-holding molded body 1 may not have the electronic component 15. Further, the syringe produced by using the drug-holding molded body 1 is not limited to the embodiment shown in FIG. For example, in the drug holding molded body 1 shown in FIG. 1, the syringe 10 has a cylindrical shape, but the shape is not limited to this. In addition, the drug-holding molded body 1 may be, for example, a cartridge-type syringe that is used by mounting it on a dedicated plunger, or an EpiPen (registered trademark) mainly used for self-injection.

FIG. 2 is a diagram showing an example of functional blocks of the drug-holding molded body 1 according to the first embodiment. The drug-holding molded body 1 has a control unit 110 that controls the display unit 151, the power supply unit 152, and the communication unit 153 in the electronic component 15. The control unit 110 exerts its function by an arithmetic device such as a CPU, and controls the electronic component 15 as a whole.

The control unit 110 has an output control unit 111. The output control unit 111 causes the display unit 151 to display the information transmitted from the terminal device 200 connected via the communication unit 153. For example, the output control unit 111 generates display information using the received information and notifies the display unit 151 of the generated display information.

FIG. 3 is a sequence diagram showing an example of processing of the drug holding molded body display system according to the first embodiment.

First, the terminal device 200 receives input of a patient name, a drug name, a drug amount, and a practitioner name (step S01).

Next, the terminal device 200 transmits the input information to the drug holding molded body 1 (step S02).

Next, the output control unit 111 of the drug-holding molded body 1 displays the received information (step S03). Specifically, the output control unit 111 generates display information using the information received via the communication unit 153, and causes the display unit 151 to display the patient name, drug name, drug amount, and practitioner name. .. Then, the medicine holding molded body 1 and the terminal device 200 end the processing of this flowchart.

The above information displayed on the display unit 151 by the terminal device 200 receiving an input is an example, and other information may be received, or any one of the exemplified information may not be received. For example, it is possible to display various kinds of information useful during treatment or storage, such as treatment instruction information, personal information such as a patient's medical history, and drug solution information. Further, for example, when the terminal device 200 receives the input of the identification information such as the patient ID, the identification information or the name of the patient corresponding to the identification information may be displayed on the display unit 151.

As described above, since the drug-holding molded body 1 of the present embodiment has excellent durability, it can be repeatedly used by a predetermined treatment, and the environmental load can be suppressed as compared with discarding immediately after use. Further, even when the drug-holding molded body 1 of the present embodiment is discarded after use, since it is of natural origin, it is possible to reduce the effect on the environment as compared with a petroleum-derived molded body.

Further, when the drug holding molded body 1 is repeatedly used, the information displayed on the display unit 151 can be changed each time the drug holding molded body 1 is used, and the convenience is improved. In addition, since the information to be displayed can be collectively managed by the terminal device 200, human error such as erroneous administration due to insufficient confirmation can be suppressed, and management efficiency of information regarding treatment and information regarding drugs can be improved.

<Modification>

Next, the medicine holding molded body 1 in the modified example of the first embodiment will be described. Hereinafter, points different from the first embodiment will be described.

FIG. 4 is a diagram showing an example of functional blocks of the drug-holding molded body 1 according to the modification of the first embodiment. The drug-holding molded body 1 according to the present modification includes a control unit 110, a display unit 151, a power supply unit 152, a communication unit 153, and an input unit 154 and a storage unit 155 as the electronic component 15.

The input unit 154 includes an input device that receives an input operation. For example, the input unit 154 is installed on the exterior body and receives an input operation by detecting a touch operation using electricity supplied from the power supply unit 152 as power. As an example, the input unit 154 has a substrate containing cellulose nanofibers. The detection method of the touch operation of the input unit 154 is not limited, and various detection methods such as a resistance film method that detects an operation using a resistance film laminated on a substrate and a capacitance method that detects a change in capacitance. Can be used.

Note that the input device may be a touch panel that also has a function as the display unit 151. The input device may be, for example, a pointing device that receives an operation of a pointer displayed on the display unit 151, a hardware button, or the like. Moreover, the input device may function as a biometric authentication sensor capable of acquiring biometric information.

The storage unit 155 stores information by using electricity generated by the power supply unit 152 as power. For example, the storage unit 155 is installed in an exterior body and is configured by a storage device in which a transparent substrate having cellulose nanofibers is provided with an electrode layer via an insulating layer. Note that the memory device may have an insulating layer containing cellulose nanofibers. A memory device including cellulose nanofibers is excellent in flexibility and can change its shape according to the shape of an outer package. The storage unit 155 may be configured by a storage device used in a general electronic device.

When the substrate included in the electronic component 15 is made of cellulose nanofiber, the substrate may be a part of the syringe 10. That is, the substrate included in the input unit 154 or the storage unit 155 may be a part of the exterior body. Further, at least one of the input unit 154 and the storage unit 155 may be detachable from the exterior body 10. The input device and the storage device are transparent, for example.

The control unit 110 has an input control unit 112 in addition to the output control unit 111. The input control unit 112 receives input of information via the input unit 154. For example, the input control unit 112 temporarily stores the input information in the storage unit 155.

FIG. 5 is a sequence diagram showing an example of processing of the drug holding molded body display system in the modified example of the first embodiment. The processing performed in steps S11 to S13 is the same as the processing performed in steps S01 to S03 in the sequence diagram shown in FIG.

After step S13, the input control unit 112 of the drug-holding molded body 1 accepts the input of the end of administration (step S14). Specifically, when the administration of the medicine is completed, the input control unit 112 receives an input operation indicating that the administration of the medicine is completed. For example, the input control unit 112 accepts an operation of selecting the “Yes” portion with respect to the image “Dosing has been completed? Yes or No” displayed on the display device.

Next, the communication unit 153 transmits the input information (step S15). Specifically, the communication unit 153 transmits, to the terminal device 200, information indicating that administration of the drug has ended.

Next, the terminal device 200 records information in the electronic medical chart (step S16). Specifically, the terminal device 200 refers to the electronic medical chart generated for the patient whose input is accepted in step S11, and displays information indicating that the administration of the drug of the amount and type accepted in the same step has been completed. Fill out. In addition, the terminal device 200 may perform a process of reducing the inventory of the drug.

Next, the output control unit 111 of the drug-holding molded body 1 ends the display (step S17). Specifically, the output control unit 111 ends the display of information in step S13. It does not matter whether the processing of steps S16 and S17 is performed before or after. Then, the medicine holding molded body 1 and the terminal device 200 end the processing of this flowchart.

It should be noted that the processing of this flowchart is merely an example of processing that can be performed by the drug holding molded body 1. For example, the input control unit 112 of the drug holding molded body 1 may directly accept the information input to the terminal device 200 in step S11. For example, the input control unit 112 accepts input of information about when and who administered the drug to whom via the input unit 154 and transmits the information to the terminal device 200, thereby collectively collecting information regarding drug administration. Can be managed.

Further, for example, in a prefilled syringe or the like that is circulated while holding a drug, information about the drug may be stored in the storage unit 155 and the information may be displayed according to an input operation.

When the input device has a biometric authentication sensor, by registering the biometric information of the patient or practitioner in the terminal device 200 in advance, the patient or practitioner to be administered can be efficiently managed. .. For example, at any timing of steps S13 to S15, the input unit 154 acquires the fingerprint of the operator, and the communication unit 153 transmits the fingerprint to the terminal device 200. The terminal device 200 records the practitioner identified by the received fingerprint in the electronic medical chart of the target patient.

Further, for example, at any timing of steps S13 to S15, when the patient touches the input unit 154, the input unit acquires the fingerprint of the patient and transmits the fingerprint to the terminal device 200. The terminal device 200 records information on the drug administration history in the electronic medical record of the patient identified by the received fingerprint. As described above, regarding the drug administration, the reliability of the information to be managed is improved by managing when and who administered the drug by using the biometric information. The biometric information is not limited to the fingerprint, and may be vein information, for example.

As described above, according to the present embodiment, it is possible to efficiently input/output information to/from the drug holding molded body 1. As a result, the practitioner can not only grasp the necessary information at an appropriate timing, but also manage the information input to the drug-holding molded body 1 and improve work efficiency in a medical setting.

<Second Embodiment>

Next, the drug holding molded body 2 according to the second embodiment will be described. Hereinafter, points different from the first embodiment will be described.

FIG. 6 is a diagram showing an example of the external appearance of the drug holding molded body 2 according to the second embodiment. The drug-holding molded body 2 is an infusion pack and has an exterior body 20 and an electronic component 25. The outer package 20 is formed of a material containing cellulose nanofibers, like the syringe 10 in the first embodiment.

The electronic component 25 includes a display unit 251, a power supply unit 252, and a communication unit 253. The display unit 251, the power supply unit 252, and the communication unit 253 are the same as the display unit 151, the power supply unit 152, and the communication unit 153, and thus the description thereof will be omitted. Note that the electronic component 25 may include the input unit 154 and the storage unit 155, as in the modification of the first embodiment.

That is, the display unit 251 uses information supplied from the terminal device 200 connected via the communication unit 253 by using the electric power supplied from the power supply unit 252, or an input operation to an input unit included in the electronic component 25. Display whether it is the acquired information.

The drug-holding molded body 2 is not limited to a syringe or an infusion pack. For example, all drug holding containers such as ampoules, vials, and cartridges for holding drugs can be formed by the drug holding molded body 2 of the present embodiment.

As described above, in the present embodiment, by configuring the drug holding container with the drug holding molded body 2, it is possible to provide a medical material in consideration of suppression of environmental load. Further, also in the medicine holding container, by displaying necessary information, it is possible to contribute to improvement of medical efficiency.

Although the respective embodiments and modifications according to the present invention have been described above, the present invention is not limited to the above-described examples of the embodiments and includes various modifications. For example, one example of the above-described embodiment is described in detail for the sake of easy understanding of the present invention, and the present invention is not limited to one including all the configurations described here. Further, it is possible to replace a part of the configuration of an example of an embodiment with the configuration of another example. In addition, it is possible to add another example configuration to an example configuration of an embodiment. Further, with respect to a part of the configuration of the example of each embodiment, other configurations may be added, deleted, or replaced. Further, each of the above-mentioned configurations, functions, processing units, processing means, etc. may be realized in hardware by designing a part or all of them with, for example, an integrated circuit. Further, the control lines and information lines in the figure show those considered necessary for explanation, and not all are shown. It may be considered that almost all configurations are connected to each other.

The configurations of the drug-holding molded bodies 1 and 2 described above can be classified into more components according to the processing content. Also, one component can be classified so as to perform more processing.

1.2: molded article for holding drug, 10: syringe, 11: cylinder tip, 12: needle, 13: finger flange, 14: plunger, 15/25: electronic component, 20: exterior body, 110: control unit, 111 : Output control unit, 112: input control unit, 151/251: display unit, 152/252: power supply unit, 153/253: communication unit, 154: input unit, 155: storage unit, 200: terminal device

Claims (14)

It has an exterior body that holds the drug inside,
The drug-holding molded body, wherein the outer package is formed of a material containing a natural polymer nanofiber. The drug holding molded body according to claim 1,
A communication unit that connects to other devices,
A display unit installed on the exterior body, for displaying information received from the other device via the communication unit,
The said display part is a drug holding molded object which has a board|substrate containing a natural polymer nanofiber. The drug holding molded body according to claim 2,
A drug-holding molded body, which is provided on the exterior body, has a substrate containing natural polymer nanofibers, and has an input unit that receives an input operation. The drug holding molded body according to claim 3,
When the drug name to be held is received from the other device, it has a control unit for displaying the received information on the display unit,
The drug holding molded body, which notifies the other device when the control unit receives an input of information indicating the end of drug administration via the input unit. The drug-holding molded body according to claim 3 or 4,
The input unit has a biometric sensor capable of acquiring biometric information,
The said communication part is a drug holding molded body which transmits the said biometric information which the said input part acquired to the said other apparatus. The drug holding molded body according to any one of claims 2 to 5,
A power generation unit having a substrate containing natural polymer nanofibers and a power generation layer, which is installed in the exterior body,
The said display part is a chemical|medical agent holding molded object which displays using the electricity which the said electric power generation part generated as power. The drug holding molded body according to any one of claims 2 to 6,
The said communication part is a drug holding molded object which has a board|substrate containing a natural polymer nanofiber. The drug-holding molded body according to any one of claims 2 to 7,
A drug-holding molded body, which is provided on the outer package, has a substrate containing natural polymer nanofibers, and has a storage unit for storing information. The drug holding molded body according to any one of claims 2 to 8,
The drug-holding molded body, wherein the exterior body and the substrate are transparent. The drug holding molded body according to any one of claims 2 to 9,
The drug holding molded body, wherein the substrate is at least a part of the exterior body. The drug holding molded body according to any one of claims 1 to 10, wherein
The natural polymer nanofiber is a cellulose nanofiber, which is a drug-holding molded body. The drug holding molded body according to any one of claims 1 to 11,
A drug-holding molded article, which is installed on the outer package and has an electronic tag in which identification information for identifying a drug is recorded in a readable manner. A syringe comprising the drug-holding molded body according to any one of claims 1 to 12, and having the exterior body as a syringe. A drug holding container comprising the drug holding molded body according to any one of claims 1 to 12.

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