JP2020036959A - Syringe, cylinder holder, and medical solution injection system - Google Patents

Abstract

To provide a syringe and a cylinder holder that are hardly damaged even when a liquid having a high viscosity is injected with high pressure, and a medical solution injection system using them.SOLUTION: A syringe 30 for an injection device is mounted to a cylinder holder 11 for holding a flange 22 of the syringe with a cylinder holder groove 14 and fixing the syringe. An inner wall surface 15 on a syringe side of the cylinder holder has a linear part, and a guide 31 also has a linear part so that the syringe is fixed only when flange cut parts 25 are positioned up and down, and the rotation is prohibited, thereby making a pressure receiving area in injection large.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a syringe and a cylinder holder suitable for performing injection at a high injection pressure using a drive mechanism such as an automatic injection device.

  In various fields including medical applications, syringes are used for injecting liquid. Injection of a high-viscosity drug solution such as a contrast agent for X-ray CT imaging or a contrast agent for MRI (magnetic resonance imaging apparatus) requires a high pressure and is difficult or difficult to operate manually. It takes time and effort. Therefore, injection is generally performed using a mechanical syringe drive mechanism such as an automatic injection device. FIG. 11 shows a state in which the syringe 20 is mounted on such an automatic injection device 10. The automatic injection device 10 includes a cylinder holder 11, a piston holder 12, and a motor (not shown) inside. The cylinder holder 11 fixes a syringe outer cylinder 21 by holding a flange 22. Hold the flange 24. By moving the piston holder forward or backward by the motor, the piston 23 can be relatively moved with respect to the syringe outer cylinder, and liquid can be injected (liquid is discharged from the syringe) or sucked. FIG. 12 is a view showing a state where a syringe is mounted on the automatic injection device.

  As shown in FIG. 13, when a small-sized syringe is mounted on the automatic injection device, a syringe outer cylinder is mounted on a detachable adapter 13 (which functions as a cylinder holder for the syringe). Then, it is attached to the automatic injection device 10. FIG. 14 shows a state where the syringe is mounted on the automatic injection device.

  FIG. 15 is a view for explaining holding and positioning of the syringe by the cylinder holder of the automatic injection device shown in FIG. 11, and is a view of the syringe barrel viewed from the rear side. That is, as shown in FIG. 11 and FIG. 15A, the flange is cut into the groove of the cylinder holder 11 with the flange cut portion 25 vertical. Next, the flange is fixed by rotating it by 90 ° so that the flange does not come off. FIG. 15 (b) is a diagram showing a state during rotation, and FIG. 15 (c) is a use position.

  The cut portion of the flange is used for positioning as described above, and is also necessary for preventing the syringe from being damaged by rolling when left on a flat surface such as a tabletop.

Further, the syringe shown here is a large-sized (100 mL, 200 mL) syringe having a generally popular shape having a syringe outer cylinder and a piston. While a typical 50-60 mL syringe has a pressure resistance of about 3 kg / cm ² , the pressure resistance is increased to about 20 kg / cm ² for injection of a contrast agent.

  By the way, as a syringe for a contrast agent, there is a type without a piston. In this type, a female screw provided on a member fixing the packing is connected to a male screw at the tip of a shaft on the side of the injection device, and the shaft is driven back and forth to suction and inject the contrast agent. However, such a syringe having no piston is dedicated to an injector, and therefore, must always use an automatic injector when aspirating a medical solution. Therefore, during the diagnosis, the automatic injection device is occupied, and the liquid medicine cannot be sucked.

  On the other hand, a general-purpose syringe as shown in FIG. 11 and the like is capable of manually sucking a chemical solution, so that the automatic injection device does not need to be occupied at the time of suction, so that the syringe can be used even during diagnosis. And there is an advantage that a chemical solution for the next test can be prepared in advance by filling the liquid. In addition, as shown in FIGS. 11 and 13, there is also an advantage that the same injection device can be used by using an adapter even with syringes having different sizes, and that the syringe can be easily attached to the device. .

  As described above, syringes for injecting a drug solution such as a contrast agent have been variously improved so far.However, when a drug solution having a high viscosity such as a contrast agent is injected, a large force is applied to the flange. If the flange surface receiving the pressure is small, the syringe may be damaged. If the injection is performed in a halfway state as shown in FIG. 15B without the flange being rotated to the predetermined position, the risk of breakage increases because the pressure receiving area is small.

  Recently, a mechanism for injecting a syringe using a relatively large syringe of about 200 mL has been devised, in which the cylinder holder is made movable and a flange is easily and more securely mounted. FIG. 16 is an enlarged view of a cylinder holder portion of such an automatic injection device 10. This cylinder holder has two clamps 16, and before the syringe is mounted, the upper parts of the two clamps are open as shown in FIG. Then, as shown in FIG. 17A (upper left side diagram in FIG. 17), the syringe is fitted into the two clamps 16 with the flange cut surface vertical and the syringe opened. As the fitting is performed, the two clamps 16 are pushed by the flange, rotate around the fulcrum 17, and become closed. Then, by rotating the syringe by 90 °, the flange cut surface 25 is fixed up and down as shown in FIG. FIG. 17C is a plan view (the clamp portion is a cross-sectional view) of the fixed state viewed from above.

  However, even if such a clamp mechanism is used, if it is fixed at a halfway position on the way from FIG. 17 (a) to FIG. 17 (b), the pressure receiving area of the flange at the time of injection becomes small. Similarly, the risk of syringe breakage increases.

  Therefore, an object of the present invention is to provide a syringe that is not easily damaged even when a high-viscosity liquid is injected at a high pressure, and a cylinder holder used together with the syringe.

  The present invention relates to the following items.

1. A syringe which is mounted on a cylinder holder for holding the syringe flange by the cylinder holder groove and fixing the syringe, and which can be used for an injection device,
The cylinder holder is provided with a positioning mechanism capable of fitting with the concave portion,
The syringe has a concave portion fitted with the positioning mechanism.

  2. The syringe according to claim 1, wherein the recess is provided on a flange of the syringe.

  3. The syringe according to claim 1, wherein the recess is provided in a reinforcing rib in which a rear end surface of a flange of the syringe is partially thickened.

  4. The syringe according to any one of claims 1 to 3, wherein the positioning mechanism is a latch pushed by a coil spring.

  5. The syringe according to any one of claims 1 to 3, wherein the positioning mechanism is a leaf spring having a claw.

6. A cylinder holder for holding the flange of the syringe according to any one of the above 1 to 3 by a cylinder holder groove and fixing the syringe to an injection device,
A cylinder holder having a positioning mechanism that fits into a recess provided in the syringe.

  7. 7. The cylinder holder according to claim 6, wherein the positioning mechanism is a latch pressed by a coil spring.

  8. 7. The cylinder holder according to claim 6, wherein the positioning mechanism is a leaf spring having a claw.

  9. The cylinder holder according to any one of the above items 6 to 8, wherein the cylinder holder is integrated with the injection device.

  10. The cylinder holder according to any one of claims 6 to 8, wherein the cylinder holder is an adapter that is detachably attached to the injection device.

  11. The cylinder holder according to any one of the above items 6 to 10, wherein the fitting between the positioning mechanism and the concave portion occurs when the syringe is rotated by 90 ° after the syringe is mounted on the cylinder holder. Cylinder holder.

  12. An injection device comprising: the cylinder holder according to any one of 6 to 11; a piston holder that holds a piston of a syringe and can move relatively to the cylinder holder; and a drive mechanism that moves the piston holder.

  13. A drug solution injection system comprising: the syringe according to any one of the above 1 to 3; and the injection device according to the above item 12.

  This application also discloses the following matters. That is, one of the disclosures of the present application is a syringe that is mounted on a cylinder holder for holding a syringe flange by a cylinder holder groove and fixing the syringe, and can be used for an injection device, The present invention relates to a syringe having a guide which engages with a cylinder holder and defines a mounting direction of a mounted syringe.

  In one aspect of the disclosure of the present application, the guide is a protrusion having a thickness that does not fit into the groove of the cylinder holder, wherein the flange fits into the groove, while the guide does not fit into the cylinder holder groove. Then, engagement with the cylinder holder occurs, thereby inhibiting rotation of the cylinder and holding and fixing the syringe in a predetermined direction.

  At this time, if the cylinder holder has a vertical portion on the inner wall surface on the syringe side and a linear portion is formed on the guide so as to engage with the vertical portion, the rotation of the cylinder is reduced. Forbidden, the syringe can be held and fixed in a predetermined direction.

  Further, as the cylinder holder, one provided with two clamps, in which the two clamps are in an open state before mounting the syringe, and operating so that the upper part of the clamp closes inward with mounting the syringe to fix the flange is used. It is also possible that the guide is adapted to the shape of the clamp so that rotation of the syringe is inhibited.

  Further, the present invention is a syringe which is mounted on a cylinder holder for holding a syringe flange by a cylinder holder groove and fixing the syringe, and which can be used for an injection device, wherein the cylinder holder has a recessed portion. The present invention relates to a syringe provided with a positioning mechanism that can be fitted, wherein the syringe has a concave portion that fits with the positioning mechanism.

  This positioning mechanism is preferably a latch pressed by a coil spring or a leaf spring having a claw.

  Further, the present invention relates to a cylinder holder having a positioning mechanism capable of fitting into a concave portion of a syringe provided with these concave portions.

  Further, according to the present invention, the above-mentioned syringe, a cylinder holder for holding the flange of the syringe by the cylinder holder groove and fixing the syringe, and holding the piston of the syringe and moving relative to the cylinder holder can be provided. The present invention relates to a drug solution injection system including a piston holder and an injection device having a drive mechanism for moving the piston holder.

  According to the present invention, the direction of the syringe is determined in a predetermined direction, that is, preferably, the direction in which the flange cut portion is vertically directed to the mounting direction to the cylinder holder, and the fixing position can be confirmed. Is fixed. As a result, the contact area with the groove wall surface of the cylinder holder increases, and a sufficient pressure receiving area can be secured during injection. Therefore, stable implantation can be performed with respect to the breakdown voltage.

It is a figure showing one form of a syringe of other inventions indicated by this application, and a state held and fixed with a cylinder holder. (A-1) A view before the syringe is seen from the back of the syringe. (A-2) A top view of the syringe and the syringe holder. (B-1) A view after the syringe is seen from the back of the syringe. (B-2) Top view after mounting the syringe It is a figure showing one form of a syringe and a cylinder holder of the present invention. (A) A view before the syringe is seen from the back of the syringe. (B) A view after the syringe is seen from the back of the syringe. It is a figure showing one form of a syringe and a cylinder holder of the present invention. (A) A view before the syringe is seen from the back of the syringe. (B) A view after the syringe is seen from the back of the syringe. It is a figure showing one form of a syringe and a cylinder holder of the present invention. (A) View of the state before mounting the syringe from the back of the syringe. (B) View of state after mounting the syringe viewed from the back of the syringe. (C) Top view of the syringe. It is a figure showing one form of a syringe and a cylinder holder of the present invention. (A) View from the back of the syringe, showing the state before mounting the syringe. (B) View from the back of the syringe, showing the state during mounting of the syringe. (C) View from the rear of the syringe, showing the state after mounting the syringe. Figure It is a figure showing one form of a syringe of other inventions indicated by this application, and a state held and fixed with a cylinder holder. (A) A view of the state of mounting the syringe from the front of the syringe. (B) A view of the state after mounting the syringe from the front of the syringe. (C) A top view of the state after mounting the syringe. It is a figure showing one form of a syringe of other inventions indicated by this application, and a state held and fixed with a cylinder holder. (A) A view of the state of mounting the syringe viewed from the back of the syringe. (B) A view of the state after mounting the syringe viewed from the back of the syringe. (C) Top view of the state after mounting the syringe. It is a figure showing one form of the syringe of other inventions indicated by the present application. It is a figure showing one form of the syringe of other inventions indicated by the present application. It is a figure showing one form of the syringe of other inventions indicated by the present application. It is a figure showing signs that a syringe is attached to an automatic injection device. It is a figure showing signs that a syringe was attached to an automatic injection device. It is a figure showing signs that a syringe is attached to an automatic injection device using an adapter. It is a figure showing signs that a syringe was attached to an automatic injection device. FIG. 12 is a diagram illustrating holding and positioning of a syringe by a cylinder holder of the automatic injection device illustrated in FIG. 11. It is a figure showing a cylinder holder provided with two movable clamps. It is a figure explaining holding and positioning of a syringe by a cylinder holder provided with two movable clamps. (A) A view of the state of mounting the syringe viewed from the back of the syringe. (B) A view of the state after mounting the syringe viewed from the back of the syringe. (C) Top view of the state after mounting the syringe.

  Hereinafter, the present invention will be described with reference to the drawings. The specific examples of the present invention are shown in FIGS. 2, 3, 4, and 5, and those shown in FIGS. 1, 6, 7, 8, 9, and 10 are: This is a specific example of another invention disclosed in the present application.

  FIG. 1 is a view showing a syringe 30 in a form in which a guide is provided on a flange portion of the syringe, and (a-1) is a view of a state before mounting the syringe viewed from a rear surface of the syringe, and (a-2). Is a top view of the syringe and the syringe holder, (b-1) is a view of the state after mounting the syringe as viewed from the back of the syringe, and (b-2) is a top view after mounting the syringe.

  In this embodiment, a guide 31 is provided on the rear surface of the flange 22. On the other hand, the groove 14 of the cylinder holder 11 is formed with a thickness enough to fit the flange 22, but is formed with a groove width smaller than the thickness including the guide 31. Therefore, as shown in FIG. 1A, the flange is fitted into the cylinder holder 11 so that the guide 31 faces vertically. FIG. 1B is a diagram showing a state where the flange 22 is fitted into the cylinder holder 11. In this example, since the inner wall surface 15 on the syringe side of the cylinder holder 11 has a straight portion, while the guide 31 also has a straight portion, the syringe is provided only at the position where the flange cut portion 25 comes up and down. Is fixed and rotation is prohibited. Therefore, the area where the flange is held is large, and the pressure receiving area during injection can be increased.

  Further, the guide can be provided on the front side of the flange. FIG. 8 is a view of the syringe provided with the guide on the front side of the flange, as viewed from the distal end side. As shown in this figure, the guide 33 is provided on the front side of the flange (the tip side of the syringe) with a thickness at least such that the guide 33 does not fit into the cylinder holder groove. The syringe is mounted and fixed only in the direction in which the surface 25 faces up and down.

  As a guide, it is easier to mount the guide if it has a linear portion, but the position can be defined by a guide 35 including a plurality of dots as shown in FIG. Further, when the interval between the two guides is shortened on the mounting side as in the guide 37 in the example of FIG. 10, the mounting becomes easy.

  FIG. 2 is a diagram illustrating an example of a syringe in which a positioning cut 41 is provided in a flange cut portion 25 of the flange 22 as a concave portion to be fitted with a positioning mechanism. On the other hand, on the cylinder holder side, a latch 42 is provided as a positioning mechanism to be fitted with the positioning cut 41, and the latch is always pushed in the center direction by the coil spring 43. 2A, the flange is fixed at a position where the positioning cut 41 and the latch 42 engage (FIG. 2B). . At this time, since there is a click feeling, it is possible to confirm the setting position even by touch, so that the reliability is improved. In the present invention, the cylinder holder has a groove, and refers to a structure for fixing the syringe by holding the flange of the syringe with the groove, even if the cylinder holder is integrated with the injection device, Alternatively, it may be detachable like an adapter as shown in FIG.

  FIG. 3 shows an example in which the positioning cut 51 is provided not in the flange cut portion 25 of the flange 22 but in the circular arc portion 26. In such a case, as shown in FIG. 3B, it is preferable that the latch 52 be provided on the side of the cylinder holder so that the latch 52 is pushed toward the center by the coil spring 53. When the holder is manually rotated by 90 ° after being mounted on the cylinder holder in the direction as shown in FIG. 3A, the positioning cut 51 and the latch 52 engage (FIG. 3B), and the flange is fixed. As shown in this figure, it is preferable to provide the latches 52 on both sides since the fixing position is particularly stable.

  In the example of FIG. 2, the positioning cut is provided in the flange cut portion, and in the example of FIG. 3, the positioning cut is provided in the arc portion of the flange. However, in addition to the normal flange portion, a recess for positioning may be provided separately. FIG. 4 shows one example. In this example, a flange reinforcing rib 61 may be provided on the rear end surface of the flange, and a part of the rib may be formed as a positioning portion 62 that fits with the latch 63. Here, as shown in FIG. 4 (c), the flange reinforcing rib 61 is formed by partially thickening the rear end surface of the flange, thereby strengthening the flange and preventing breakage. In this example, similarly to the example shown in FIG. 2, after being mounted on the cylinder holder in the direction of FIG. 4A and then manually rotated by 90 °, the positioning part 62 and the latch 63 are clicked with a click feeling. Engagement (FIG. 4 (b)) fixes the flange.

  FIG. 5 shows a syringe in which a positioning cut 51 is provided in the circular arc portion 26 of the flange 22 in the same manner as the example shown in FIG. 3, while a claw leaf spring having a claw 72 is provided on the cylinder holder side. It is a figure showing the example in which 71 was provided. After mounting the flange cut portion vertically on the cylinder holder as shown in FIG. 5 (a), rotate the syringe as shown in FIG. 5 (b), and further rotate the syringe at 90 ° as shown in FIG. 5 (c). The pawl 72 is fitted and fixed to the positioning cut 51 with a click feeling.

  FIG. 6 is a diagram showing an example of an improved fixing method using a clamp as shown in FIGS. 16 and 17. The syringe of this example has a structure in which a guide 81 is provided on the front surface of a flange of a syringe outer cylinder 80 as shown in FIG. FIGS. 6A and 6B show how the syringe is attached when viewed from the direction A (from the distal end direction) in FIG. 6C. As shown in FIG. 6 (a), when the flange cut surface 25 is turned up and down and pushed into the clamp 82 with the syringe open, the clamp 82 rotates around the fulcrum 83 as shown in FIG. 6 (b). The upper part of the clamp is closed and the syringe is mounted and fixed. Because the guide 81 is provided, the guide portion does not fit into the groove of the clamp, so that the syringe cannot be mounted at a position other than the position where the flange cut surface 25 comes up and down. Therefore, the pressure receiving area at the time of injection can be increased.

  FIG. 7 is also a diagram showing an example of an improved fixing method using a clamp as shown in FIGS. 16 and 17. In the example of the syringe shown in FIG. 6, the guide is provided in the front direction of the flange, but in the example of FIG. 7, a rib is provided on the rear surface of the flange of the syringe outer cylinder 90 as shown in FIG. And FIGS. 7A and 7B show how the syringe is attached when viewed from the direction A (from the rear side) in FIG. 7C. Similarly, in this case, when the syringe is pushed into the clamp 92 with the flange cut surface 25 facing up and down as shown in FIG. 7A, the clamp 92 rotates around the fulcrum 93 and the clamp 92 shown in FIG. It is mounted and fixed as described above, but cannot be mounted if the position of the flange cut surface is shifted due to the function of the guide 91.

  As described above, the present invention has been described with reference to typical examples. However, the present invention is not limited to these examples, and various modifications can be made without departing from the gist of the present invention. Further, in the above example, the pressure receiving area was maximized when the flange cut surface was at the vertical position, but depending on the form of the cylinder holder, the flange cut surface does not necessarily have to be at the vertical position. And can be changed as appropriate.

  The syringe of the present invention is preferably used together with an injection device, particularly an automatic injection device.

  When the syringe has a guide that engages with the cylinder holder and determines the mounting direction of the syringe to be mounted, a cylinder holder that engages with the syringe and can define the mounting direction of the syringe is used. When used with an automatic injection device having a piston holder and a drive mechanism for the piston holder as described with reference to FIGS. 11 and 13, even a chemical solution having a high viscosity can be easily injected. In particular, it is suitably used for injection of various contrast agents as a drug solution.

  It should be noted that a known structure can be used for the structure, drive mechanism, and the like of the piston holder of the automatic injection device.

  Furthermore, the syringe of the present invention is preferably a general-purpose syringe using a combination of a syringe outer cylinder and a piston, but may be of any other type as long as the syringe needs to fix and fix the flange surface.

  Advantageous Effects of Invention According to the present invention, it is possible to provide a syringe and a cylinder holder that are not easily damaged even when a high-viscosity liquid is injected at a high pressure, and a chemical injection system using them.

Reference Signs List 10 automatic injection device 11 cylinder holder 12 piston holder 13 adapter 14 cylinder holder groove 15 cylinder holder inner wall surface 16 clamp 17 fulcrum 21 syringe outer cylinder 22 flange 23 piston 24 piston flange 25 flange cut section 26 arc section 30 syringe 31 guide 33 guide 35 Guide 37 Guide 41 Positioning cut 42 Latch 43 Coil spring 51 Positioning cut 52 Latch 53 Coil spring 61 Flange reinforcing rib 62 Positioning portion 63 Latch 71 Claw leaf spring 72 Claw 80 Syringe outer cylinder 81 Guide 82 Clamp 83 Support point 90 Syringe outer cylinder 91 Guide 92 Clamp 93 fulcrum

Claims (13)

A syringe which is mounted on a cylinder holder for holding the syringe flange by the cylinder holder groove and fixing the syringe, and which can be used for an injection device,
The cylinder holder is provided with a positioning mechanism capable of fitting with the concave portion,
The syringe has a concave portion fitted with the positioning mechanism.   The syringe according to claim 1, wherein the recess is provided in a flange of the syringe.   The syringe according to claim 1, wherein the recess is provided in a reinforcing rib in which a rear end surface of a flange of the syringe is partially thickened.   The syringe according to claim 1, wherein the positioning mechanism is a latch pushed by a coil spring.   The syringe according to any one of claims 1 to 3, wherein the positioning mechanism is a leaf spring having a claw. A cylinder holder for holding the syringe flange according to any one of claims 1 to 3 by a cylinder holder groove and fixing the syringe to an injection device,
A cylinder holder having a positioning mechanism that fits into a recess provided in the syringe.   The cylinder holder according to claim 6, wherein the positioning mechanism is a latch pressed by a coil spring.   The cylinder holder according to claim 6, wherein the positioning mechanism is a leaf spring having a claw.   The cylinder holder according to any one of claims 6 to 8, wherein the cylinder holder is integrated with the injection device.   The cylinder holder according to any one of claims 6 to 8, wherein the cylinder holder is an adapter detachably attached to the injection device.   The fitting of the positioning mechanism and the concave portion occurs when the cylinder holder rotates by 90 degrees after the syringe is mounted on the cylinder holder. Cylinder holder.   An injection device comprising: the cylinder holder according to any one of claims 6 to 11; a piston holder that holds a piston of a syringe and can move relatively to the cylinder holder; and a drive mechanism that moves the piston holder.   A drug solution injection system comprising: the syringe according to claim 1; and the injection device according to claim 12.

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