JP2019535267A5 - - Google Patents

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Publication number
JP2019535267A5
JP2019535267A5 JP2019525814A JP2019525814A JP2019535267A5 JP 2019535267 A5 JP2019535267 A5 JP 2019535267A5 JP 2019525814 A JP2019525814 A JP 2019525814A JP 2019525814 A JP2019525814 A JP 2019525814A JP 2019535267 A5 JP2019535267 A5 JP 2019535267A5
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JP
Japan
Prior art keywords
fusion polypeptide
gdnf
domain
pharmaceutical composition
gdnf fusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019525814A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019535267A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2017/060953 external-priority patent/WO2018089702A1/en
Publication of JP2019535267A publication Critical patent/JP2019535267A/ja
Publication of JP2019535267A5 publication Critical patent/JP2019535267A5/ja
Pending legal-status Critical Current

Links

JP2019525814A 2016-11-10 2017-11-09 Gdnf融合ポリペプチド及びその使用方法 Pending JP2019535267A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662420480P 2016-11-10 2016-11-10
US62/420,480 2016-11-10
PCT/US2017/060953 WO2018089702A1 (en) 2016-11-10 2017-11-09 Gdnf fusion polypeptides and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2019535267A JP2019535267A (ja) 2019-12-12
JP2019535267A5 true JP2019535267A5 (OSRAM) 2020-12-24

Family

ID=62110755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019525814A Pending JP2019535267A (ja) 2016-11-10 2017-11-09 Gdnf融合ポリペプチド及びその使用方法

Country Status (7)

Country Link
US (2) US11912750B2 (OSRAM)
EP (1) EP3538560A4 (OSRAM)
JP (1) JP2019535267A (OSRAM)
CN (1) CN110461880A (OSRAM)
AU (2) AU2017357931B2 (OSRAM)
CA (1) CA3043179A1 (OSRAM)
WO (1) WO2018089702A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018089715A1 (en) 2016-11-10 2018-05-17 Keros Therapeutics, Inc. Activin receptor type iia variants and methods of use thereof
WO2018089702A1 (en) 2016-11-10 2018-05-17 Keros Therapeutics, Inc. Gdnf fusion polypeptides and methods of use thereof
IL320014A (en) 2018-01-12 2025-06-01 Keros Therapeutics Inc Activin receptor type iib variants and methods of use thereof
BR112021024636A2 (pt) * 2019-06-10 2022-01-18 Infectious Disease Res Inst Métodos e composições de replicons de astrovírus
IL299048A (en) * 2020-06-14 2023-02-01 Vertex Pharma Variants of complement factor - 1 fusion structures and preparations containing them and their uses
CN113046381A (zh) * 2021-04-12 2021-06-29 南华大学 用于分离生物体内特异性蛋白-dna复合体的方法、融合蛋白及其制备方法
CN115927288A (zh) * 2022-07-28 2023-04-07 南京林业大学 一种固定化脂肪tll酶及固体结合肽在其固定化中的应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
GB8909916D0 (en) * 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
US20040175795A1 (en) 1991-09-20 2004-09-09 Amgen Inc. Glial derived neurotrophic factor
ATE275197T1 (de) 1991-09-20 2004-09-15 Amgen Inc Glial neurotrophe faktor
US5733875A (en) 1994-11-15 1998-03-31 Amgen Inc. Methods of using GDNF as a neuroprotective agent
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
AU5576796A (en) 1995-04-26 1996-11-18 Regeneron Pharmaceuticals, Inc. Methods of using neurotrophic factors to enhance neuronal gr afts
US6184200B1 (en) 1995-09-28 2001-02-06 Amgen Inc. Truncated glial cell line-derived neurotrophic factor
US5731284A (en) 1995-09-28 1998-03-24 Amgen Inc. Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
US5641749A (en) 1995-11-29 1997-06-24 Amgen Inc. Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
AU1121997A (en) 1995-11-29 1997-06-19 Amgen, Inc. Method for treating sensory neuropathy using glial cell line-derived neurotrophic factor (gdnf) protein product
US5641750A (en) 1995-11-29 1997-06-24 Amgen Inc. Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product
US5837681A (en) 1996-02-23 1998-11-17 Amgen Inc. Method for treating sensorineural hearing loss using glial cell line-derived neurotrophic factor (GDNF) protein product
US5929041A (en) 1996-02-23 1999-07-27 Amgen Inc. Method for preventing and treating sensorineural hearing loss and vestibular disorders using glial cell line-derived neurotrophic factor(GDNF) protein product
US5741778A (en) 1996-03-19 1998-04-21 Amgen Inc. Method for treating Huntington's disease using glial cell line-derived neurotrophic factor (GDNF) protein product
US6455277B1 (en) 1996-04-22 2002-09-24 Amgen Inc. Polynucleotides encoding human glial cell line-derived neurotrophic factor receptor polypeptides
US7138251B1 (en) 1996-04-22 2006-11-21 Amgen Inc. Polynucleotides encoding a neurotrophic factor receptor
JP2002505576A (ja) 1997-05-30 2002-02-19 アムジエン・インコーポレーテツド 神経栄養因子レセプター
AU2354600A (en) 1998-12-09 2000-06-26 Amgen, Inc. Grnf4 a neurotrophic factor
US7160924B2 (en) 2002-07-19 2007-01-09 The General Hospital Corporation Protein conjugates with a water-soluble biocompatible, biodegradable polymer
DE60041564D1 (de) 1999-12-24 2009-03-26 Genentech Inc Verfahren und Zusammensetzungen zur Verlängerung der Entsorgungshalbwertszeit von biowirksamen Verbindungen
EP1594530A4 (en) * 2003-01-22 2006-10-11 Human Genome Sciences Inc HYBRID PROTEINS OF ALBUMIN
US8946151B2 (en) 2003-02-24 2015-02-03 Northern Bristol N.H.S. Trust Frenchay Hospital Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen
BRPI0511755A (pt) * 2004-06-01 2008-01-02 Domantis Ltd composições, fusões e conjugados de drogas e métodos de produção, tratamento e utilização
WO2006031994A2 (en) 2004-09-14 2006-03-23 Xencor, Inc. Monomeric immunoglobulin fc domains
US8008453B2 (en) * 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US8497246B2 (en) * 2006-08-18 2013-07-30 Armagen Technologies, Inc. Methods for diagnosing and treating CNS disorders by trans-blood-brain barrier delivery of protein compositions
ES2415604T3 (es) * 2007-05-30 2013-07-26 Postech Academy-Industry- Foundation Proteínas de fusión de inmunoglobulina
WO2008145139A1 (en) * 2007-05-31 2008-12-04 Genmab A/S Fusion or linked proteins with extended half life
WO2009070597A2 (en) * 2007-11-26 2009-06-04 Armagen Technologies, Inc. Fusion proteins for delivery of gdnf to the cns
AU2010258052A1 (en) * 2009-06-11 2012-01-12 Angiochem Inc. Fusion proteins for delivery of GDNF and BDNF to the central nervous system
JP2013511281A (ja) 2009-11-23 2013-04-04 アムジェン インコーポレイテッド 単量体抗体Fc
US9469676B2 (en) 2011-04-13 2016-10-18 Bristol-Myers Squibb Company Fc fusion proteins comprising novel linkers or arrangements
US20160296632A1 (en) * 2013-11-13 2016-10-13 Aequus Biopharma, Inc. Engineered glycoproteins and uses thereof
ES2913840T3 (es) 2014-03-20 2022-06-06 Bristol Myers Squibb Co Dominios de tipo III de fibronectina de unión a seroalbúmina
WO2018089702A1 (en) 2016-11-10 2018-05-17 Keros Therapeutics, Inc. Gdnf fusion polypeptides and methods of use thereof

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