JP2019524846A - 子宮内膜症の治療のための投与レジメン - Google Patents

子宮内膜症の治療のための投与レジメン Download PDF

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Publication number
JP2019524846A
JP2019524846A JP2019509559A JP2019509559A JP2019524846A JP 2019524846 A JP2019524846 A JP 2019524846A JP 2019509559 A JP2019509559 A JP 2019509559A JP 2019509559 A JP2019509559 A JP 2019509559A JP 2019524846 A JP2019524846 A JP 2019524846A
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Japan
Prior art keywords
fluoro
methylene
bisbenzonitrile
triazol
dose
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Pending
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JP2019509559A
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English (en)
Japanese (ja)
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JP2019524846A5 (https=
Inventor
パーキン，ジャッキー
クリックスタイン，ロイド，ビー．
Original Assignee
メレオ バイオファーマ ２ リミテッド
メレオ バイオファーマ ２ リミテッド
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Application filed by メレオ バイオファーマ ２ リミテッド, メレオ バイオファーマ ２ リミテッド filed Critical メレオ バイオファーマ ２ リミテッド
Publication of JP2019524846A publication Critical patent/JP2019524846A/ja
Publication of JP2019524846A5 publication Critical patent/JP2019524846A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019509559A 2016-08-19 2017-08-21 子宮内膜症の治療のための投与レジメン Pending JP2019524846A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1614179.8A GB201614179D0 (en) 2016-08-19 2016-08-19 Dosage regimen for the treatment of endometriosis
GB1614179.8 2016-08-19
PCT/GB2017/052466 WO2018033759A1 (en) 2016-08-19 2017-08-21 Dosage regimen for the treatment of endometriosis

Publications (2)

Publication Number Publication Date
JP2019524846A true JP2019524846A (ja) 2019-09-05
JP2019524846A5 JP2019524846A5 (https=) 2020-10-01

Family

ID=57045488

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019509559A Pending JP2019524846A (ja) 2016-08-19 2017-08-21 子宮内膜症の治療のための投与レジメン

Country Status (6)

Country Link
US (1) US20190192485A1 (https=)
EP (1) EP3500305A1 (https=)
JP (1) JP2019524846A (https=)
CN (1) CN109641057A (https=)
GB (1) GB201614179D0 (https=)
WO (1) WO2018033759A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12552754B1 (en) 2025-06-11 2026-02-17 ReproNovo SA Leflutrozole compositions of matter and processes for preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010508275A (ja) * 2006-10-30 2010-03-18 デュラメド ファーマシューティカルズ インコーポレーティッド 用量漸増長期サイクル治療プログラムを利用するホルモン処置の方法
JP2014526465A (ja) * 2011-09-08 2014-10-06 ノバルティス アーゲー アロマターゼ阻害剤を含む医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749713A (en) 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
TW210334B (https=) 1990-12-12 1993-08-01 Ciba Geigy Ag
GB0302572D0 (en) * 2003-02-05 2003-03-12 Astrazeneca Ab Method of treatment
DE102010003494A1 (de) * 2010-03-31 2011-10-06 Bayer Schering Pharma Aktiengesellschaft Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010508275A (ja) * 2006-10-30 2010-03-18 デュラメド ファーマシューティカルズ インコーポレーティッド 用量漸増長期サイクル治療プログラムを利用するホルモン処置の方法
JP2014526465A (ja) * 2011-09-08 2014-10-06 ノバルティス アーゲー アロマターゼ阻害剤を含む医薬組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FERTILITY AND STERILITY, vol. 95, no. 1, JPN6021019207, 2011, pages 15 - 18, ISSN: 0004666939 *

Also Published As

Publication number Publication date
EP3500305A1 (en) 2019-06-26
CN109641057A (zh) 2019-04-16
US20190192485A1 (en) 2019-06-27
GB201614179D0 (en) 2016-10-05
WO2018033759A1 (en) 2018-02-22

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