JP2019517538A - 哺乳動物種における胚−胎仔移行を検出およびモジュレートするための改良された方法 - Google Patents
哺乳動物種における胚−胎仔移行を検出およびモジュレートするための改良された方法 Download PDFInfo
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- JP2019517538A JP2019517538A JP2018563796A JP2018563796A JP2019517538A JP 2019517538 A JP2019517538 A JP 2019517538A JP 2018563796 A JP2018563796 A JP 2018563796A JP 2018563796 A JP2018563796 A JP 2018563796A JP 2019517538 A JP2019517538 A JP 2019517538A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022173706A JP2023017861A (ja) | 2016-06-07 | 2022-10-28 | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662347075P | 2016-06-07 | 2016-06-07 | |
| US62/347,075 | 2016-06-07 | ||
| US201762442219P | 2017-01-04 | 2017-01-04 | |
| US62/442,219 | 2017-01-04 | ||
| PCT/US2017/036452 WO2017214342A1 (en) | 2016-06-07 | 2017-06-07 | Improved methods for detecting and modulating the embryonic-fetal transition in mammalian species |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173706A Division JP2023017861A (ja) | 2016-06-07 | 2022-10-28 | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019517538A true JP2019517538A (ja) | 2019-06-24 |
| JP2019517538A5 JP2019517538A5 (https=) | 2025-08-08 |
Family
ID=60578097
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018563796A Pending JP2019517538A (ja) | 2016-06-07 | 2017-06-07 | 哺乳動物種における胚−胎仔移行を検出およびモジュレートするための改良された方法 |
| JP2022173706A Pending JP2023017861A (ja) | 2016-06-07 | 2022-10-28 | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022173706A Pending JP2023017861A (ja) | 2016-06-07 | 2022-10-28 | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20190175691A1 (https=) |
| EP (1) | EP3463391A4 (https=) |
| JP (2) | JP2019517538A (https=) |
| AU (2) | AU2017278931B2 (https=) |
| CA (1) | CA3026874A1 (https=) |
| WO (1) | WO2017214342A1 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023017861A (ja) * | 2016-06-07 | 2023-02-07 | エージェックス セラピューティクス,インコーポレーテッド | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
| US12404493B2 (en) | 2015-12-07 | 2025-09-02 | Agex Therapeutics, Inc. | Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells |
| US12421513B2 (en) | 2013-06-05 | 2025-09-23 | Reverse Bioengineering, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11078462B2 (en) | 2014-02-18 | 2021-08-03 | ReCyte Therapeutics, Inc. | Perivascular stromal cells from primate pluripotent stem cells |
| US10240127B2 (en) | 2014-07-03 | 2019-03-26 | ReCyte Therapeutics, Inc. | Exosomes from clonal progenitor cells |
| CN108665091A (zh) * | 2018-04-07 | 2018-10-16 | 深圳供电局有限公司 | 一种基于机器学习的物资智能调度方法 |
| US20210180013A1 (en) * | 2018-04-23 | 2021-06-17 | Agex Therapeutics, Inc. | Improved methods for inducing tissue regeneration and senolysis in mammalian cells |
| CA3135200A1 (en) * | 2019-03-28 | 2020-10-01 | Agex Therapeutics, Inc. | Induced tissue regeneration using extracellular vesicles |
| US20220316013A1 (en) * | 2019-08-23 | 2022-10-06 | Agex Therapeutics, Inc. | Differentially-methylated regions of the genome useful as markers of embryo-adult transitions |
| US20240066070A1 (en) * | 2021-01-12 | 2024-02-29 | Agex Therapeutics, Inc. | Methods for the ex vivo induction of tissue regeneration in microbiopsies |
| WO2023064572A2 (en) * | 2021-10-15 | 2023-04-20 | Agex Therapeutics, Inc. | Methods for the temporal regulation of reprogramming factors in mammalian cells |
| WO2023114274A1 (en) * | 2021-12-14 | 2023-06-22 | Agex Therapeutics, Inc. | Improved methods for inducing the maturation of mammalian cells |
| WO2025155772A1 (en) * | 2024-01-19 | 2025-07-24 | Gene Company (Pty)Ltd. | Alpha-1 anti-trypsin upregulating polynucleotides and method of use and treatment thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014197421A1 (en) * | 2013-06-05 | 2014-12-11 | Biotime, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| CN105435244A (zh) * | 2015-12-02 | 2016-03-30 | 重庆高圣生物医药有限责任公司 | Lin28a基因过表达腺相关病毒在促进创伤修复中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009067245A2 (en) * | 2007-11-20 | 2009-05-28 | University Of Florida Research Foundation, Inc. | Compositions and methods for tissue repair |
| US20130202564A1 (en) * | 2010-04-09 | 2013-08-08 | University Of Southern California | Systems and Methods of Cell Activated, Controlled Release Delivery of Growth Factors for Tissue Repair and Regeneration |
| ES2590461T3 (es) * | 2010-07-02 | 2016-11-22 | Fundación Centro Nacional De Investigaciones Oncológicas Carlos Iii | La transcriptasa inversa de la telomerasa como protección frente al envejecimiento |
| AU2017278931B2 (en) * | 2016-06-07 | 2023-06-29 | Agex Therapeutics, Inc. | Improved methods for detecting and modulating the embryonic-fetal transition in mammalian species |
-
2017
- 2017-06-07 AU AU2017278931A patent/AU2017278931B2/en active Active
- 2017-06-07 JP JP2018563796A patent/JP2019517538A/ja active Pending
- 2017-06-07 WO PCT/US2017/036452 patent/WO2017214342A1/en not_active Ceased
- 2017-06-07 EP EP17810984.9A patent/EP3463391A4/en active Pending
- 2017-06-07 CA CA3026874A patent/CA3026874A1/en active Pending
-
2018
- 2018-12-06 US US16/211,690 patent/US20190175691A1/en not_active Abandoned
-
2021
- 2021-12-06 US US17/542,997 patent/US20220088137A1/en not_active Abandoned
- 2021-12-06 US US17/542,992 patent/US20220160833A1/en active Pending
- 2021-12-06 US US17/543,020 patent/US20220088138A1/en not_active Abandoned
-
2022
- 2022-10-28 JP JP2022173706A patent/JP2023017861A/ja active Pending
-
2023
- 2023-06-16 AU AU2023203808A patent/AU2023203808A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014197421A1 (en) * | 2013-06-05 | 2014-12-11 | Biotime, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| CN105435244A (zh) * | 2015-12-02 | 2016-03-30 | 重庆高圣生物医药有限责任公司 | Lin28a基因过表达腺相关病毒在促进创伤修复中的应用 |
Non-Patent Citations (2)
| Title |
|---|
| CELL, vol. 155(4), JPN6021015789, 2013, pages 778 - 792, ISSN: 0004811852 * |
| THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 53, JPN6021015791, 2014, pages 343 - 351, ISSN: 0004562709 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12421513B2 (en) | 2013-06-05 | 2025-09-23 | Reverse Bioengineering, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| US12492400B2 (en) | 2013-06-05 | 2025-12-09 | Reverse Bioengineering, Inc. | Compositions and methods for induced tissue regeneration in mammalian species |
| US12404493B2 (en) | 2015-12-07 | 2025-09-02 | Agex Therapeutics, Inc. | Methods for the re-derivation of diverse pluripotent stem cell-derived brown fat cells |
| JP2023017861A (ja) * | 2016-06-07 | 2023-02-07 | エージェックス セラピューティクス,インコーポレーテッド | 哺乳動物種における胚-胎仔移行を検出およびモジュレートするための改良された方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023017861A (ja) | 2023-02-07 |
| AU2023203808A1 (en) | 2023-07-13 |
| AU2017278931B2 (en) | 2023-06-29 |
| US20190175691A1 (en) | 2019-06-13 |
| EP3463391A1 (en) | 2019-04-10 |
| AU2017278931A1 (en) | 2018-12-20 |
| US20220088137A1 (en) | 2022-03-24 |
| EP3463391A4 (en) | 2020-01-22 |
| CA3026874A1 (en) | 2017-12-14 |
| US20220088138A1 (en) | 2022-03-24 |
| US20220160833A1 (en) | 2022-05-26 |
| WO2017214342A1 (en) | 2017-12-14 |
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| US12421513B2 (en) | Compositions and methods for induced tissue regeneration in mammalian species | |
| JP7419347B2 (ja) | 哺乳動物細胞における組織再生の誘導及びセノリシスのための改良された方法 | |
| US20240066070A1 (en) | Methods for the ex vivo induction of tissue regeneration in microbiopsies | |
| US20240398987A1 (en) | Methods for the temporal regulation of reprogramming factors in mammalian cells | |
| US20240350553A1 (en) | Methods for modulating the regenerative phenotype in mammalian cells |
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