JP2019513829A5 - - Google Patents
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- Publication number
- JP2019513829A5 JP2019513829A5 JP2019503603A JP2019503603A JP2019513829A5 JP 2019513829 A5 JP2019513829 A5 JP 2019513829A5 JP 2019503603 A JP2019503603 A JP 2019503603A JP 2019503603 A JP2019503603 A JP 2019503603A JP 2019513829 A5 JP2019513829 A5 JP 2019513829A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- propiolyl
- acetyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 claims 18
- -1 propiolyl Chemical group 0.000 claims 10
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 7
- 125000000217 alkyl group Chemical group 0.000 claims 7
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 5
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000002541 furyl group Chemical group 0.000 claims 2
- 125000005956 isoquinolyl group Chemical group 0.000 claims 2
- 125000001624 naphthyl group Chemical group 0.000 claims 2
- 125000004076 pyridyl group Chemical group 0.000 claims 2
- 125000005493 quinolyl group Chemical group 0.000 claims 2
- 125000001544 thienyl group Chemical group 0.000 claims 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- UUEVFMOUBSLVJW-UHFFFAOYSA-N oxo-[[1-[2-[2-[2-[4-(oxoazaniumylmethylidene)pyridin-1-yl]ethoxy]ethoxy]ethyl]pyridin-4-ylidene]methyl]azanium;dibromide Chemical compound [Br-].[Br-].C1=CC(=C[NH+]=O)C=CN1CCOCCOCCN1C=CC(=C[NH+]=O)C=C1 UUEVFMOUBSLVJW-UHFFFAOYSA-N 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 229940127557 pharmaceutical product Drugs 0.000 claims 1
- 239000000651 prodrug Substances 0.000 claims 1
- 229940002612 prodrug Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012453 solvate Substances 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 206010046766 uterine cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662320654P | 2016-04-11 | 2016-04-11 | |
| US62/320,654 | 2016-04-11 | ||
| PCT/CA2017/050432 WO2017177316A1 (en) | 2016-04-11 | 2017-04-10 | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019513829A JP2019513829A (ja) | 2019-05-30 |
| JP2019513829A5 true JP2019513829A5 (cg-RX-API-DMAC7.html) | 2020-05-21 |
Family
ID=60041299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503603A Ceased JP2019513829A (ja) | 2016-04-11 | 2017-04-10 | 抗炎症剤、抗転移剤及び／又は抗癌剤として使用するためのアミノ安息香酸誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10759754B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3442943B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2019513829A (cg-RX-API-DMAC7.html) |
| CN (1) | CN109071433A (cg-RX-API-DMAC7.html) |
| CA (1) | CA3020348A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017177316A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| CA2916662C (en) | 2013-06-25 | 2022-03-08 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
| SG11202006246PA (en) | 2018-01-17 | 2020-07-29 | Aurigene Discovery Tech Ltd | Substituted alkynylene compounds as anticancer agents |
| CA3021417A1 (en) * | 2018-10-18 | 2020-04-18 | 3R Valo, S.E.C. | Aminobenzoic acid derivatives for use as anti-inflammatory agents, anti-metastatic agents and/or anticancer agents |
| CN114516819B (zh) * | 2022-02-25 | 2024-02-27 | 顺毅宜昌化工有限公司 | 一种n,n’-二乙酰基肼的制备方法 |
| CN117447353B (zh) * | 2023-09-21 | 2025-12-30 | 爱斯特（成都）生物制药股份有限公司 | 一种氘可来昔替尼中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046301A (en) | 1959-10-29 | 1962-07-24 | Burroughs Wellcome Co | Method of making chlorambucil |
| AU2005327921A1 (en) * | 2004-11-01 | 2006-08-31 | University Of Southern California | Novel compounds for treatment of cancer and disorders associated with angiogenesis function |
| JP6948708B2 (ja) * | 2015-06-19 | 2021-10-13 | センチュリオン バイオファーマ コーポレイション | 薬物制御放出のための送達系 |
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2017
- 2017-04-10 US US16/091,721 patent/US10759754B2/en not_active Expired - Fee Related
- 2017-04-10 EP EP17781669.1A patent/EP3442943B1/en not_active Not-in-force
- 2017-04-10 CA CA3020348A patent/CA3020348A1/en not_active Abandoned
- 2017-04-10 CN CN201780022811.3A patent/CN109071433A/zh active Pending
- 2017-04-10 WO PCT/CA2017/050432 patent/WO2017177316A1/en not_active Ceased
- 2017-04-10 JP JP2019503603A patent/JP2019513829A/ja not_active Ceased
-
2020
- 2020-08-07 US US16/988,332 patent/US20210002222A1/en not_active Abandoned