JP2019501224A5 - - Google Patents
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- Publication number
- JP2019501224A5 JP2019501224A5 JP2018554651A JP2018554651A JP2019501224A5 JP 2019501224 A5 JP2019501224 A5 JP 2019501224A5 JP 2018554651 A JP2018554651 A JP 2018554651A JP 2018554651 A JP2018554651 A JP 2018554651A JP 2019501224 A5 JP2019501224 A5 JP 2019501224A5
- Authority
- JP
- Japan
- Prior art keywords
- carboxylic acid
- trifluoromethyl
- chromene
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662276713P | 2016-01-08 | 2016-01-08 | |
| US62/276,713 | 2016-01-08 | ||
| US201662277225P | 2016-01-11 | 2016-01-11 | |
| US62/277,225 | 2016-01-11 | ||
| PCT/US2017/012737 WO2017120591A1 (en) | 2016-01-08 | 2017-01-09 | Combination of a chromene compound and a second active agent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019501224A JP2019501224A (ja) | 2019-01-17 |
| JP2019501224A5 true JP2019501224A5 (https=) | 2020-02-13 |
| JP6942726B2 JP6942726B2 (ja) | 2021-09-29 |
Family
ID=59274050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018554651A Active JP6942726B2 (ja) | 2016-01-08 | 2017-01-09 | クロメン化合物および第２活性薬剤の併用薬 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20170196835A1 (https=) |
| EP (1) | EP3400218A4 (https=) |
| JP (1) | JP6942726B2 (https=) |
| KR (1) | KR20180100652A (https=) |
| CN (1) | CN108779091B (https=) |
| AU (1) | AU2017206108B2 (https=) |
| MX (1) | MX388579B (https=) |
| WO (1) | WO2017120591A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX383920B (es) | 2016-05-26 | 2025-03-14 | Recurium Ip Holdings Llc | Compuestos inhibidores de egfr. |
| CN110869055B (zh) * | 2017-07-20 | 2023-04-28 | 国立大学法人北海道大学 | 靶向pd-1/pd-l1的抑制剂与cox-2抑制剂的组合使用 |
| IL264068B2 (en) | 2018-01-05 | 2023-07-01 | Great Novel Therapeutics Biotech & Medicals Corp | Aggregate and pharmaceutical preparation containing an hdac inhibitor and an nsaid aggregate together with an immune checkpoint inhibitor for use in a method for removing immunosuppression in the microenvironment of a tumor or stimulating an immune system against cancer cells |
| TWI869398B (zh) * | 2019-05-10 | 2025-01-11 | 英商拜西克爾德有限公司 | 治療癌症之方法 |
| JP2022553421A (ja) * | 2019-10-28 | 2022-12-22 | エンジーケム ライフサイエンシーズ コーポレーション | がんの処置のための方法および組成物 |
| AU2020384481B2 (en) | 2019-11-12 | 2025-12-11 | Nammi Therapeutics, Inc. | Formulated and/or co-formulated liposome compositions containing IDO antagonist prodrugs useful in the treatment of cancer and methods thereof |
| EP4143196A4 (en) | 2020-04-29 | 2024-04-17 | Relay Therapeutics, Inc. | PI3K-A INHIBITORS AND METHODS OF USE THEREOF |
| EP4412606A4 (en) * | 2021-10-07 | 2025-09-24 | Relay Therapeutics Inc | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF |
| KR102889598B1 (ko) * | 2023-02-16 | 2025-11-21 | 주식회사 재인알앤피 | 신규한 데커신 유도체, 및 이의 비소세포폐암 예방 또는 치료 용도 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6034256A (en) | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
| US20040127470A1 (en) | 1998-12-23 | 2004-07-01 | Pharmacia Corporation | Methods and compositions for the prevention or treatment of neoplasia comprising a Cox-2 inhibitor in combination with an epidermal growth factor receptor antagonist |
| US20020103141A1 (en) | 1998-12-23 | 2002-08-01 | Mckearn John P. | Antiangiogenic combination therapy for the treatment of cancer |
| AR038957A1 (es) | 2001-08-15 | 2005-02-02 | Pharmacia Corp | Terapia de combinacion para el tratamiento del cancer |
| WO2009009776A2 (en) | 2007-07-12 | 2009-01-15 | Tragara Pharmaceuticals, Inc. | Patient selection and therapeutic methods using markers of prostaglandin metabolism |
| CN102757417B (zh) * | 2012-06-18 | 2014-09-24 | 中国科学院广州生物医药与健康研究院 | 氘代苯并吡喃类化合物及其应用 |
| US9682143B2 (en) * | 2012-08-14 | 2017-06-20 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| CN103012350B (zh) * | 2012-12-07 | 2015-02-04 | 中国科学院广州生物医药与健康研究院 | 苯并吡喃类手性化合物的合成方法 |
| CN103044477B (zh) | 2012-12-07 | 2015-08-05 | 中国科学院广州生物医药与健康研究院 | 三甲基硅取代苯并吡喃类化合物及其应用 |
| US9452228B2 (en) | 2013-04-01 | 2016-09-27 | Immunomedics, Inc. | Antibodies reactive with an epitope located in the N-terminal region of MUC5AC comprising cysteine-rich subdomain 2 (Cys2) |
| WO2014163684A1 (en) * | 2013-04-03 | 2014-10-09 | Ibc Pharmaceuticals, Inc. | Combination therapy for inducing immune response to disease |
| US20160312297A1 (en) | 2013-12-17 | 2016-10-27 | Merck Sharp & Dohme Corp. | Pd-l1 gene signature biomarkers of tumor response to pd-1 antagonists |
| PE20170255A1 (es) | 2014-01-24 | 2017-03-22 | Dana Farber Cancer Inst Inc | Moleculas de anticuerpo que se unen a pd-1 y usos de las mismas |
| US11034757B2 (en) | 2014-06-09 | 2021-06-15 | Biomed Valley Discoveries, Inc. | Combination therapies using agents that target tumor-associated stroma or tumor cells and tumor vasculature |
-
2017
- 2017-01-09 EP EP17736519.4A patent/EP3400218A4/en not_active Withdrawn
- 2017-01-09 US US15/401,777 patent/US20170196835A1/en not_active Abandoned
- 2017-01-09 WO PCT/US2017/012737 patent/WO2017120591A1/en not_active Ceased
- 2017-01-09 CN CN201780012465.0A patent/CN108779091B/zh active Active
- 2017-01-09 AU AU2017206108A patent/AU2017206108B2/en active Active
- 2017-01-09 KR KR1020187022783A patent/KR20180100652A/ko not_active Ceased
- 2017-01-09 JP JP2018554651A patent/JP6942726B2/ja active Active
- 2017-01-09 MX MX2018008433A patent/MX388579B/es unknown
-
2022
- 2022-05-13 US US17/744,185 patent/US12544356B2/en active Active
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