JP2019142532A - Refrigeration transportation package and kit thereof - Google Patents

Abstract

To provide a configuration capable of maintaining a prescribed storage temperature for a prescribed period of time, and a refrigeration transportation package configured to suppress an effect on a change in an environmental temperature and easily manufactured at low cost without using any special coolant or packing material.SOLUTION: A refrigeration transportation package comprises: a second heat-insulating case (5) having a transported article holding space (HA) for holding an inner package (10) comprising a first heat-insulating case (2) that houses a transported article (1), a first cardboard case (3), and a cushioning material sheet (4), and a cold insulation unit holding space (HB) for housing and holding a side cold insulation unit (8) so as to face the four sides of the first cardboard case (3), and is configured such that a top-surface cold insulation unit (9) is disposed on the top surface of the inner package (10) covered with a heat-insulating cushioning sheet (6), each of the side cold insulation unit (8) and the top-surface cold insulation unit (9) is integrally structured with a frozen body and a refrigerated body, and the refrigerated body is interposed between the frozen body and the inner package (10).SELECTED DRAWING: Figure 1

Description

  The present invention relates to a refrigerated transport package and kit for use in transporting articles that require strict quality control, such as pharmaceuticals, in particular, temperature control that maintains a low temperature.

  The quality of pharmaceuticals is greatly related to human life, and deterioration of quality is an essential item that must be avoided during transportation and storage. Careful attention is required to prevent quality deterioration. In quality control in the transportation and storage of pharmaceutical products, proper temperature control is particularly important. Some pharmaceutical products are subjected to particularly strict temperature control in transportation and storage. For example, some pharmaceutical products are required to be maintained within a temperature range of 2 ° C to 8 ° C.

  Regarding transportation and storage of pharmaceuticals, the WHO (World Health Organization) has strict guidelines on the distribution of pharmaceuticals and has established Good Distribution Practice (GDP). In recent years, in Japan, the pharmaceutical industry has been required to respond to GDP.

  Packing forms having various structures have been proposed as packing bodies used for transportation and storage of pharmaceuticals and the like. Patent Document 1 proposes a low-temperature transport packaging apparatus having a configuration in which an aqueous cryogen (coolant) frozen in advance is provided on the outer peripheral surface of an object to be transported. The low-temperature transport packaging apparatus of Patent Document 1 has a configuration in which a spacer is provided in order to secure a space between a transport object and a packaging container, and an aqueous cooling agent is placed on the spacer. Patent Document 2 proposes a temperature management system for a container in which two types of heat storage agents (cooling agents) having different melting points are provided above and below a container having thermal conductivity. Patent Document 3 discloses a first housing portion that can store a solidified heat storage agent, a second storage portion that can store a non-solidified heat storage agent, and a third storage that can store a solidified heat storage agent. The storage container provided with the part is proposed, The structure which prevents that the thermal storage agent from which temperature differs in a predetermined | prescribed accommodating part is reliably accommodated and a thermal storage agent is arrange | positioned accidentally is shown. Patent Document 4 discloses a thermostatic box in which two or more kinds of cool storage agents (cooling agents) are provided around the outer periphery of the inner box, and the stored items in the thermostat box are stored in accordance with the outside air temperature. A configuration for specifying the temperature of the is shown.

Japanese Patent No. 4335721 Japanese Patent No. 5759805 Japanese Patent Laid-Open No. 2016-11795 JP-A-9-68376

  As described above, in the transportation and storage of pharmaceuticals as articles, various packaging forms have been proposed for temperature control, and particularly in the field of refrigerated transportation of pharmaceuticals, a specific temperature range, for example, 2 ° C. Since it is necessary to maintain the temperature within a range of -8 ° C, it is necessary to adjust the temperature, number (capacity), arrangement, and the like of the coolant according to the surrounding environment. In addition, during transportation, the surrounding environment changes and the environment temperature is likely to be affected. Particularly in the summer, there is a problem that the storage time for maintaining the storage temperature within a predetermined temperature range is shortened. Furthermore, when a frozen product having a temperature of −10 ° C. or lower is used as the coolant, for example, the temperature of the storage space for storing the medicine or the like may temporarily exceed the specified storage temperature range depending on the number of the frozen products and the arrangement. Could drop below freezing.

  Furthermore, in the conventional packing form as described above, since a special coolant and packing material are used, the cost for transportation and management is high. In particular, in the transportation of medicines, the package is often discarded (one-way transportation) by only one transportation, and the expensive packaging has a problem of increasing the transportation cost.

  In the refrigerated transport package used for refrigerated transport of pharmaceuticals, the present invention prevents the temperature of the storage space for storing the transported articles from being below freezing even if it is temporary, and is within a predetermined storage temperature range. Refrigerated transport packaging that provides a structure that can be maintained for a long time, has a structure that suppresses the influence of changes in the outside air temperature, which is the environmental temperature, and can be easily manufactured at low cost without using any special coolant or packaging material The purpose is to provide the body and its kit.

The refrigerated transport packaging body according to one aspect of the present invention,
A first heat insulating case for storing and holding a transport article and having heat insulation properties;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
A shock-absorbing cushioning sheet that wraps around the first paperboard case;
A side cold-retaining unit disposed on the four side surfaces of the first paperboard case via the cushioning material sheet and serving as a cooling source for the transported article;
One transport article holding space for holding the inner package body composed of the first heat insulating case, the first paperboard case, and the cushioning material sheet storing the transport article at a substantially central position, and the side cooling unit provided with the first cold storage unit. A second heat-insulating case having four heat-retaining unit holding spaces disposed and held via the cushioning material sheet so as to face the four sides of one paperboard case, and having heat insulation properties;
The inner package body that is disposed on the inner wall surface that forms the transport article holding space and the cold insulation unit holding space in the second heat insulating case, and is housed and held in the transport article holding space, and is stored in the cold insulation unit holding space. A heat-insulating cushion sheet that covers the held side-surface cold-retaining unit and has heat insulation, shock absorption, and flexibility;
A top surface cooling unit that is disposed on the top surface of the inner package covered with the heat insulating cushioning sheet and serves as a cooling source for the transported article;
A top surface heat insulating sheet that covers the top of the top surface cold insulation unit together with the inner package and has heat insulation properties, and a paperboard case that houses the second heat insulation case together with the top surface cold insulation unit and the top surface heat insulation sheet. A corrugated cardboard attached to at least one surface, and a rectangular parallelepiped case,
Each of the side surface cooling unit and the top surface cooling unit is configured by integrating a frozen body and a refrigerated body, and is arranged such that the refrigerated body is interposed between the frozen body and the inner package body. ing.

Refrigerated transport packaging kit according to another aspect of the present invention,
A first heat insulation case having heat insulation properties for storing and holding a transport article;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the paperboard case on the four sides of the first paperboard case. Side cooling unit that serves as a cooling source for articles,
One transport article holding space for holding an inner packing body including the first heat insulating case and the first paperboard case containing the transported article in a substantially central position, and the side cold-retaining unit for the four sides of the first paperboard case. A second heat-insulating case having four heat-retaining unit holding spaces that are arranged so as to oppose each other and are stored and held;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the inner package body on the top surface of the inner package body. A top surface cooling unit that serves as a cooling source for the article, and a paperboard case that houses the second heat insulating case together with the top surface cooling unit, and is configured in a rectangular parallelepiped shape with corrugated cardboard attached to at least one surface An outer case.

  According to the present invention, even if the internal temperature of the storage space for storing the transported article is temporary, it is prevented from becoming below freezing point, and has a configuration that can be maintained for a predetermined time within a predetermined storage temperature range, Thus, it is possible to provide a refrigerated transport packaging body and a kit thereof that have a configuration in which the influence on the change of the above is suppressed and can be easily manufactured at low cost without using a special coolant or packaging material.

The perspective view which decomposed | disassembled and showed a part of internal structure in the refrigerated transport packaging body of Embodiment 1 which concerns on this invention. The perspective view which showed the packing contents of the inner packing body (product packing body) shown in FIG. 1, and decomposed | disassembled and showed the internal structure of the inner packing body Sectional drawing which showed typically the internal structure of the packing form in the refrigerated transport package of Embodiment 1 Sectional drawing which described the composition of the 3rd comparison packing object typically The graph which shows the temperature transition which compared the 1st comparison package and the 2nd comparison package The graph which shows the experimental result done with respect to the 3rd comparison package shown in FIG. The graph which shows the temperature transition with respect to the outdoor temperature of the summer in the refrigerated transport packaging body of Embodiment 1, and a 4th comparison packaging body The figure which showed the inner bottom face of the exterior case of Embodiment 2 which concerns on this invention The graph which shows the temperature transition when experimenting on the assumption of the winter transport of the refrigerated transport package of Embodiment 2

First, various aspects of the refrigerated transport packaging according to the present invention will be described.
The refrigerated transport package of the first aspect according to the present invention is
A first heat insulating case for storing and holding a transport article and having heat insulation properties;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
A shock-absorbing cushioning sheet that wraps around the first paperboard case;
A side cold-retaining unit disposed on the four side surfaces of the first paperboard case via the cushioning material sheet and serving as a cooling source for the transported article;
One transport article holding space for holding the inner package body composed of the first heat insulating case, the first paperboard case, and the cushioning material sheet storing the transport article at a substantially central position, and the side cooling unit provided with the first cold storage unit. A second heat-insulating case having four heat-retaining unit holding spaces disposed and held via the cushioning material sheet so as to face the four sides of one paperboard case, and having heat insulation properties;
The inner package body that is disposed on the inner wall surface that forms the transport article holding space and the cold insulation unit holding space in the second heat insulating case, and is housed and held in the transport article holding space, and is stored in the cold insulation unit holding space. A heat-insulating cushion sheet that covers the held side-surface cold-retaining unit and has heat insulation, shock absorption, and flexibility;
A top surface cooling unit that is disposed on the top surface of the inner package covered with the heat insulating cushioning sheet and serves as a cooling source for the transported article;
A top surface heat insulating sheet that covers the top of the top surface cold insulation unit together with the inner package and has heat insulation properties, and a paperboard case that houses the second heat insulation case together with the top surface cold insulation unit and the top surface heat insulation sheet. A corrugated cardboard attached to at least one surface, and a rectangular parallelepiped case,
Each of the side surface cooling unit and the top surface cooling unit is configured by integrating a frozen body and a refrigerated body, and is arranged such that the refrigerated body is interposed between the frozen body and the inner package body. ing.

  The refrigerated transport packaging body according to the first aspect described above is configured such that the internal temperature of the storage space for storing the transported article is prevented from becoming below freezing point even temporarily, and can be maintained within a predetermined storage temperature range for a predetermined time. Have

  In the refrigerated transport package according to the second aspect of the present invention, in the first aspect, the frozen body and the refrigerated body in the side surface cooler unit and the top surface cooler unit are formed of a cooler having the same melting point. The frozen body may be initially used in a frozen state, and the refrigerated body may be initially used in a low temperature state.

  The refrigerated transport package according to the third aspect of the present invention is the refrigerated transport package according to the first or second aspect, wherein the second heat insulating case is formed in a rectangular parallelepiped, and includes the transport article holding space and the cold storage unit holding space. The space to be configured may be defined by columnar bodies of heat insulating materials formed at the four corners in plan view of the rectangular parallelepiped, and the space between adjacent columnar bodies may be configured as the cold insulation unit holding space.

  In the refrigerated transport package according to the fourth aspect of the present invention, in any one of the first to third aspects, an initial use temperature of the frozen body is in a temperature range of −20 ° C. or more and 0 ° C. or less. Yes, the initial use temperature of the refrigeration body may be a temperature range of 0 ° C. or more and 5 ° C. or less.

  The refrigerated transport packaging body according to the fifth aspect of the present invention is the refrigerated transport package according to any one of the first to fourth aspects, wherein the frozen body and the refrigerated body in the side surface cooler unit and the top surface cooler unit are the same. The structure may be integrated with the same shape, and each integrated unit may be sealed inside a bag body of shock-absorbing material having shock absorption and flexibility.

  The refrigerated transport packaging body according to the sixth aspect of the present invention is the refrigerated transport packaging body according to any one of the first to fifth aspects, wherein the inner space of the second heat insulating case includes the bottom surface of the inner packaging body and the first 2 The structure which does not arrange | position a cooling source between the inner bottom surfaces of a heat insulation case may be sufficient.

  The refrigerated transport package according to a seventh aspect of the present invention is the refrigerated transport package according to any one of the first to sixth aspects, wherein the heat insulating buffer sheet is formed of a highly foamed polyethylene sheet, The sheet may be an aluminum sheet.

  The refrigerated transport packaging body according to the eighth aspect of the present invention is the refrigerated transport packaging body according to any one of the first to sixth aspects, between the outer bottom surface of the second heat insulation case and the inner bottom surface of the exterior case. A heat generation space may be secured by providing a spacer, and heat generation means may be provided in the heat generation space.

  In the refrigerated transport package according to the ninth aspect of the present invention, in the eighth aspect, the heat generating means may be a disposable body warmer.

The refrigerated transport packaging kit according to the tenth aspect of the present invention is
A first heat insulation case having heat insulation properties for storing and holding a transport article;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the paperboard case on the four sides of the first paperboard case. Side cooling unit that serves as a cooling source for articles,
One transport article holding space for holding an inner packing body including the first heat insulating case and the first paperboard case containing the transported article in a substantially central position, and the side cold-retaining unit for the four sides of the first paperboard case. A second heat-insulating case having four heat-retaining unit holding spaces that are arranged so as to oppose each other and are stored and held;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the inner package body on the top surface of the inner package body. A top surface cooling unit that serves as a cooling source for the article, and a paperboard case that houses the second heat insulating case together with the top surface cooling unit, and is configured in a rectangular parallelepiped shape with corrugated cardboard attached to at least one surface An outer case.

  The refrigerated transport packaging kit according to the tenth aspect described above can be assembled at a low cost and can be easily manufactured without using a special coolant or packing material. It becomes. The assembled refrigerated transport packaging body has a configuration in which the internal temperature of the storage space for storing the transported article is prevented from being below freezing point even temporarily, and can be maintained within a predetermined storage temperature range for a predetermined time.

The refrigerated transport packaging kit according to the eleventh aspect of the present invention is arranged on the inner wall surface forming the transported article holding space and the cold insulation unit holding space in the second heat insulating case in the tenth aspect. And heat insulation, shock absorption, and flexibility for covering the inner package housed and held in the transport article holding space and the side surface cooling unit housed and held in the cold insulation unit holding space. It may include a heat insulating cushioning sheet, and a top surface heat insulating sheet having heat insulating properties for covering the upper part of the top surface cooling unit together with the inner package.

  The refrigerated transport packaging kit of the twelfth aspect according to the present invention is the refrigerated transport packaging kit according to the tenth aspect, wherein the frozen body and the refrigerated body in the side surface cold unit and the top surface cold unit are a cold insulator having the same melting point. The frozen body may be initially used in a frozen state, and the refrigerated body may be initially used in a low temperature state.

  Hereinafter, the refrigerated transport packaging body and the kit thereof according to the present invention will be described with reference to the drawings using embodiments with respect to specific configurations. The refrigerated transport package and its kit according to the present invention will be described as an example in which a pharmaceutical product is packed as a transport article, and is particularly maintained within a temperature range of 2 ° C. to 8 ° C. as a storage temperature range. An embodiment configured on the assumption that it is transported by a general truck will be described. However, the present invention is not limited to the configuration of the specific example described in the embodiment, and includes a configuration based on the technical idea in the embodiment described below, and quality control is severe. Even in the case where the transported article is transported while being maintained within a predetermined storage temperature range, it is possible to cope with the configuration based on the same technical idea.

  It should be noted that the numerical values, shapes, configurations, manufacturing order, and the like shown in the following embodiments are merely examples, and do not limit the present invention. Among the constituent elements in the following embodiments, constituent elements that are not described in the independent claims indicating the highest concept are described as optional constituent elements.

(Embodiment 1)
Hereinafter, Embodiment 1 of the present invention will be described in detail with reference to the accompanying drawings. 1 is an exploded perspective view showing a part of the internal structure of the refrigerated transport packaging body according to Embodiment 1 of the present invention. FIG. 1 shows an inner package (product package) 10 in which a transport article 1 that is a product (medicine) is stored and held in the central portion. The refrigerated transport package of Embodiment 1 is intended to maintain the storage temperature within a temperature range of 2 ° C. to 8 ° C. during transport (for example, 30 hours or more) of the product (medicine) that is the transport article 1 It is configured as.

  FIG. 2 shows the package contents of the inner package (product package) 10 shown in FIG. 1, and is an exploded perspective view showing the internal configuration of the inner package 10. As shown in FIG. In FIG. 2, it is shown that the inner package 10 is configured by packing the transport article 1 that is a product (medicine) with the first heat insulating case 2, the first paperboard case 3, and the cushioning material sheet 4. .

  As shown in FIG. 2, a product (medicine) that is a transport article 1 is housed and held in a first heat insulating case (product foamed polystyrene case) 2 made of a rectangular solid foamed polystyrene. The 1st heat insulation case 2 is provided with the main body 2a which has the internal space (dent) 2c corresponding to the external shape of the transport article 1, and the lid | cover 2b which seals the internal space 2c of the main body 2a. The 1st heat insulation case 2 is the structure by which the transport article 1 is accommodated and hold | maintained at the internal space 2c of the main body 2a, and the upper part of the internal space 2c is covered with the lid | cover 2b. In the first embodiment, the polystyrene foam constituting the first heat insulation case 2 has a rectangular parallelepiped shape with a thickness of 20 mm. As the external dimensions of the first heat insulating case 2 in the first embodiment, a box-shaped one having a size of 180 mm × 220 mm × 155 mm (capacity: about 6 liters) was used.

  The first heat insulating case 2 may have at least a configuration in which the transport article 1 is closely stored and held and the transport article 1 does not move inside the first heat insulating case 2. In the first embodiment, an example in which the first heat insulating case 2 is made of foamed polystyrene will be described. However, any material having heat insulating properties and impact absorbing properties can be used. As the first heat insulating case 2, any material having a thermal conductivity of 0.050 W / (m.K) or less can be used.

  The first heat insulating case 2 that stores and holds the transport article 1 as described above is stored in the first paperboard case 3. The first paperboard case 3 is formed so as to cover the first heat insulation case 2, and has a shape having an inner dimension corresponding to the outer shape of the first heat insulation case 2. The first paperboard case 3 in the first embodiment is formed of a so-called cardboard case formed of a paperboard having a multilayer structure including paper that is formed into a wave shape. The corrugated cardboard case is a paperboard case that is formed in a rectangular parallelepiped shape by attaching corrugated cardboard to at least one surface.

  As described above, the first heat insulation case (product foam case) 2 and the first paperboard case (product cardboard case) 3 for storing and holding the transported article 1 are the cushion material sheet (bubble sheet) which is a sheet-like bubble cushioning material. 4 is wrapped. In addition, the cushioning material sheet 4 is wound in one or more turns on the front, rear, left and right four side surfaces of the first paperboard case 3. In the first embodiment, the first paperboard case 3 may be configured to be wrapped by the cushioning material sheet 4. For example, the cushioning material sheet 4 is formed in a bag shape in advance, and one end thereof is opened. The first paperboard case 3 may be inserted from the opening and wrapped.

  The configuration in which the first heat insulating case 2 and the first paperboard case 3 are wrapped with the cushioning material sheet 4 as described above is an inner package (product package) 10. That is, in the inner package 10, the transport article 1 that is a product (pharmaceutical product) is triple packed by the buffer material sheet 4, the first paperboard case 3, and the first heat insulating case 2 in order from the outside.

  The refrigerated transport package of the first embodiment has a refrigerated transport package for a refrigerated transport having a special structure with respect to the inner package 10 packed as described above.

  As shown in FIG. 1, the inner package 10 is configured to be housed and held in an internal space in a second heat insulating case (cooled foamed polystyrene case) 5 made of foamed polystyrene. The 2nd heat insulation case 5 is comprised by the main body 5a and the lid | cover 5b, and is the structure by which the internal space of the main body 5a is sealed with the lid | cover 5b. The internal space of the second heat insulation case 5 has a rectangular parallelepiped shape. In the first embodiment, the polystyrene foam constituting the second heat insulating case 5 has a rectangular parallelepiped shape with a thickness of 45 mm. Moreover, the external dimensions of the second heat insulating case 5 used in Embodiment 1 were 415 mm × 465 mm × 335 mm (capacity: about 65 liters), and the thickness was 45 mm.

  In the internal space of the second heat insulating case 5 (cooled foamed polystyrene case), there is a heat insulating cushioning sheet 6 made of a non-crosslinked highly foamed polyethylene sheet having a cushioning property and excellent in heat insulating properties, waterproof properties and moisture resistance properties ( For example, Lightlon (registered trademark)) is spread. Moreover, this heat insulation buffer sheet 6 is extended from the internal space of the main body 5a so that the upper opening of the internal space of the 2nd heat insulation case 5 can be covered. The heat insulating cushioning sheet 6 extending in this way covers the upper part after the inner package 10 and the like are stored, and is stored in the internal space by the lid 5 b of the second heat insulating case 5.

  As described above, the heat insulating cushioning sheet 6 is spread over the entire wall surface of the internal space of the second heat insulating case 5 to add a heat insulating layer to the inside of the second heat insulating case 5 so as to insulate heat from the outside. While improving an effect, it has the effect of reducing the load with respect to the side surface cooling unit 8 by the heat from the outside, and keeping cold of the internal space of the 2nd heat insulation case 5 inside the space. As a result, the temperature change in the internal space of the second heat insulation case 5 is made gradual, and the effect of maintaining the predetermined temperature for a predetermined time is enhanced.

  Insulating material columns (styrofoam columns) 7, which are rectangular parallelepiped columns, are arranged at four corners in the internal space (cubic shape) of the second heat insulating case 5 laid with the heat insulating buffer sheets 6. By arranging the four heat insulating material pillars 7 in this way, a transport article holding space HA capable of arranging and storing the inner packing body 10 in a substantially central position in the inner space of the second heat insulating case 5 is secured, Cold storage unit holding spaces HB in which side cooling units 8 (described later) are arranged and held are formed on the four side portions of the inner package 10. Furthermore, by disposing the heat insulating material pillars 7 at the four corners of the inner space of the second heat insulating case 5, unnecessary cooling spaces do not exist at the four corners of the inner space of the second heat insulating case 5, and highly efficient cooling is performed. be able to. When cooling spaces are present at the four corners of the internal space, the cooling space is present at the corners of the inner package 10 to be accommodated, making it difficult to efficiently cool the inner package 10.

  As described above, in the internal space of the second heat insulating case 5, the heat insulating cushioning sheet 6 is spread and four heat insulating material columns 7 are disposed at the four corners. By arranging the heat insulating material pillars 7 at the four corners in this way, the transport article holding space HA is formed in the central portion, and the cold insulation unit holding spaces HB are formed in the four side portions. The inner package 10 is stored and held in the transport article holding space HA, and the four side surface cold-retaining units 8 are stored and held in the cold-retaining unit holding space HB. In addition, when the heat insulating material pillar 7 is closely formed at the four corners of the internal space of the second heat insulating case 5, the heat insulating buffer sheet 6 may be spread inside the heat insulating material pillar 7. The upper part of the inner package 10 and the side surface cold storage unit 8 housed and held in the internal space (transported article holding space HA and cold storage unit holding space HB) of the second heat insulating case 5 extends from the internal space. 6 to cover. At this time, the upper parts of the inner packing body 10 and the side surface cold insulation unit 8 are covered with at least the double heat insulating cushion sheet 6.

  In the internal space of the second heat insulating case 5, a top surface cold insulation unit 9 is disposed on the heat insulating cushioning sheet 6 that covers the inner package 10. As described above, at the top surface portion of the internal space of the second heat insulating case 5, the heat insulating cushioning sheet 6 is covered at least twice, so the top surface cooling unit 9 directly cools the inner package 10. To ease. In addition, since the top surface cooling unit 9 is disposed on the double heat insulating cushioning sheet 6, even when condensation occurs on the top surface cooling unit 9, the double heat insulating buffer sheet 6 applies to the product. It becomes the structure which can prevent the malfunction by dew condensation.

  Furthermore, the top opening of the internal space of the second heat insulating case 5 in which the top surface cooling unit 9 is disposed is covered with a top surface heat insulating sheet 11. In the first embodiment, the top surface heat insulating sheet 11 may be constituted by a double sheet of, for example, an aluminum sheet that is a heat insulating material and a heat insulating buffer sheet (for example, Lightlon (registered trademark)).

  The upper opening of the internal space of the second heat insulating case 5 covered with the top heat insulating sheet 11 as described above is sealed by the lid 5 b of the second heat insulating case 5. A seal tape is wound around the gap between the main body 5a and the lid 5b of the second heat insulating case 5 to ensure sealing. The sealed second heat insulation case 5 is accommodated in the second paperboard case 12 which is an exterior case. The second paperboard case 12 is formed so as to cover the second heat insulation case 5, and has a shape having an inner dimension corresponding to the outer shape of the second heat insulation case 5. The second paperboard case 12, which is the outer case in the first embodiment, is formed of so-called cardboard formed of paperboard having a multilayer structure including paper that is formed into a wavy shape. The second paperboard case 12 may be a paperboard case configured in a rectangular parallelepiped shape by attaching corrugated cardboard on at least one surface.

[Structure of cool unit]
In the refrigerated transport package of the first embodiment, as described above, the four side surface cooling units 8 and the one top surface cooling unit 9 are used as the cooling unit. The side surface cool unit 8 and the top surface cool unit 9 have the same configuration, and only the outer shape is different. In the refrigerated transport package of the first embodiment, the top surface cool unit 9 has a smaller shape than the side surface cool unit 8, and a specific configuration will be described later.

  Hereinafter, the configuration will be described using the side surface cool unit 8 and the top surface cool unit 9 as the cool unit. The cold insulation units (8, 9) are used by bringing two cold insulation agents having the same shape and configuration into close contact with each other. Examples of the cryogen include those packed with a substance containing 99% or more of water, a highly water-absorbent resin (for example, a crosslinked sodium salt of an acrylic acid polymer (main component)), and a preservative. Used.

  In the refrigerated transport package of the first embodiment, it is used as a frozen body in which the initial use temperature of one of the cooling agents (first cooling agents) 13 in the cooling unit (8, 9) is frozen at a temperature of −20 ° C. The initial use temperature of the other cooling agent (second cooling agent) 14 is used as a refrigerated body refrigerated to a temperature of 4 ° C. In the refrigerated transport package of the first embodiment, the initial use temperature is set and used. However, the present invention is not limited to such a temperature, and the side cooler unit 8 and the top cooler unit 9 are not limited thereto. , The first cryogen 13 frozen body is initially used in a frozen state of −20 ° C. or higher and 0 ° C. or lower, and the second cryogen 14 refrigerated body is 0 ° C. or higher in a low temperature state (0 ° C. or higher and 5 ° C. or lower). Configured for initial use. In this way, the cold-reserving units (8, 9) closely adhere the frozen first cold-reserving agent 13 and the second cold-reserving agent 14 to the buffer material bag (for example, a bag-shaped bubble cushioning material). It is housed and integrated. The 1st cold storage agent 13 and the 2nd cold storage agent 14 in a cold storage unit (8, 9) are formed with the same component which has the same melting | fusing point.

  As described above, the cold-reserving unit (8, 9) is composed of the frozen first cold-retaining agent 13 and the second cold-reserving agent 14, and the second cold-retaining agent 14 is the inner package 10. It arrange | positions so that it may become the side of. That is, in the refrigerated transport package of Embodiment 1, each of the cold storage units (8, 9) is arranged such that the first cold insulation 13 of the frozen body is on the outside and the second cold insulation 14 of the cold storage is on the inside. It arrange | positions in the interior space of the 2nd heat insulation case (cold insulation foam polystyrene case) 5. As shown in FIG.

  FIG. 3 is a cross-sectional view schematically showing the internal configuration of the packing form in the refrigerated transport package of Embodiment 1, and is a cross-sectional view of the refrigerated transport package cut along a plane parallel to the horizontal plane. As shown in FIG. 3, a product (pharmaceutical product) which is a transported article 1 is arranged in the approximate center of a refrigerated transport package, and a first heat insulating case (product foamed polystyrene case) 2 and a first paperboard case (product cardboard case) ) 3 and the cushioning material sheet (bubble sheet) 4 are arranged to constitute the inner package 10 (product package).

  In addition, four side surface cold-retaining units 8 are disposed on the outer side surfaces of the inner package (product package) 10, and heat insulating material columns (foamed polystyrene columns) 7 are disposed at the four corners. In this manner, by arranging the heat insulating material pillars 7 at the four corners of the internal space of the second heat insulating case 5, the transport article holding space HA in which the inner package 10 is stored and held, and the side surface cooling unit 8 are stored and held. A cold insulation unit holding space HB is formed. By forming the transport article holding space HA, it becomes easy to incorporate the inner package 10 into the second heat insulating case 5. In addition, since the transport article holding space HA is formed, a predetermined amount of the side cold-retaining unit 8 can be easily and reliably placed at a predetermined position, and the workability is excellent. Further, in the internal space of the second heat insulating case 5, the unnecessary cooling space is occupied by the heat insulating material pillar (foamed polystyrene pillar) 7, and a highly efficient cooling structure is obtained.

  In the configuration of the first embodiment, the inner packing body 10, the heat insulating material column 7, and the side surface cold insulation unit 8 are covered with the heat insulating buffer sheet 6 and stored in the internal space of the second heat insulating case 5. Further, the second heat insulation case 5 is accommodated in a second paperboard case 12 made of cardboard as an exterior case.

  In the refrigerated transport package according to the first embodiment, the first and second cooling agents 13 and 14 as specific side surface cooling units 8 have substantial dimensions of 220 mm (vertical) × 180 mm (horizontal) × 20 mm ( (Thickness) of 600 g of a cryogen was used. Moreover, the 1st cold storage agent 13 and the 2nd cold storage agent 14 as the top surface cold storage unit 9 used 400 g of cold storage agents with a substantial dimension of 190 mm (length) × 160 mm (width) × 20 mm (thickness). The external dimensions of the first heat insulating case (product foamed polystyrene case) 2 of the inner package 10 to be kept cold by these cold insulating agents (13, 14) were 180 mm × 220 mm × 155 mm and the thickness was 20 mm. Moreover, the external dimensions of the 2nd heat insulation case 5 which accommodates the side surface cool unit 8 were 415 mm x 465 mm x 335 mm, and thickness was 45 mm.

  Further, in the configuration of the first embodiment, in the internal space of the second heat insulating case 5, a cooling agent as a cooling source is disposed between the outer bottom surface of the inner package 10 and the inner bottom surface of the second heat insulating case 5. It is configured not to. According to the inventor's experiment, when a cooling agent is disposed between the outer bottom surface of the inner package 10 and the inner bottom surface of the second heat insulating case 5, the internal temperature of the inner package 10 is reduced to 0 ° C. or less. The situation became too cold.

  In the refrigerated transport package of the first embodiment, the side cooler unit 8 constituted by the first cooler 13 and the second cooler 14 is substantially at the center of the four inner side surfaces in the inner space of the second heat insulating case 5. It arrange | positions at the part and it arrange | positions so that the 2nd cold insulating agent 14 which is a refrigeration body may oppose the inner package body 10. FIG. The arrangement state of these side surface cold-retaining units 8 is held by the heat insulating material columns (foamed polystyrene columns) 7 disposed at the four corners of the internal space of the second heat insulating case 5. Therefore, the shape of the heat insulating material column 7 is set according to the inner package 10 and the side surface cold-retaining unit 8 disposed in the internal space of the second heat insulating case 5.

  As described above, the refrigerated transport package of Embodiment 1 can be easily manufactured with a simple configuration without using a special coolant or packing material.

[Temperature transition in refrigerated transport packaging]
The inventor created a refrigerated transport package of various configurations as a comparative example in addition to the configuration of the refrigerated transport package of the first embodiment, and assumed that transport by truck using these refrigerated transport packages. An experiment was conducted on the transition between the outside temperature and the inside temperature under the conditions. Hereinafter, the experimental result will be described.

  First, the structure of the 1st comparison package-the 4th comparison package created as a comparative example is demonstrated. In the first comparison package to the fourth comparison package, packing was performed using the inner package 10 containing the product (pharmaceutical product) that is the transport article 1 described in the first embodiment.

  In the first comparative packing body, the four side surfaces and the bottom surface of the inner packing body 10 were arranged so as to oppose a -20 ° C. cryogen as a frozen body. Therefore, the cushioning material sheet 4 which is a sheet-like bubble cushioning material is disposed between the product and the cold insulator, and the cushioning material sheet 4 which is the foam cushioning material sheet is also disposed on the top surface side of the product. Yes. That is, in the first comparison package, in a state where the product is wrapped in the cushioning material sheet 4, the entire side surface and the bottom surface are arranged so that only the -20 ° C. cryogen that is a frozen body is opposed. The inner packing body 10 is simply housed inside a foamed polystyrene case serving as an exterior.

  In the inner package 10 in which the product is wrapped in the cushioning material sheet 4, the second comparison package is a first cold-reserving agent 13 that is a frozen body at −20 ° C. on the side surface and the bottom surface, and a refrigerator at 4 ° C. The cold insulation unit 8 comprised with the 2nd cold insulating agent 14 is arrange | positioned so that it may oppose. In the second comparative package, the side and bottom surfaces of the inner package 10 are arranged so that the second cold insulation agent 14 that is a refrigeration body in the cold insulation unit 8 is entirely opposed. That is, the cold insulation unit 8 is provided to face the corner portion of the inner package 10. As described above, the second comparative packing body includes the inner packing body 10 and the inside of the foamed polystyrene case in which the cold insulation unit 8 disposed so as to face substantially the entire side surface and bottom surface of the inner packing body 10 is an exterior. It is the structure stored in. A gap inside the foamed polystyrene case serving as the exterior is filled with a cushioning material sheet.

  The third comparison package has a configuration in which, in the above-described second comparison package, the inner package 10 is double-wrapped with the cushioning material sheet 4 and the side surface of the inner package 10 is surrounded by a partition plate 15 of polystyrene foam. . FIG. 4 is a cross-sectional view schematically showing the configuration of the third comparison package. (A) of FIG. 4 is the cross-sectional view which cut | disconnected the 3rd comparison packing body by the surface parallel to a horizontal surface. FIG. 4B is a longitudinal sectional view of the third comparative packing body as viewed from the side.

  As shown in FIG. 4, in the third comparative packing body, the side surface of the inner packing body 10 that is double-wrapped by the cushioning material sheet 4 is surrounded and held by the partition plate 15, and the cold insulation unit is provided on the outside thereof. 8 is arranged. In the third comparative packing body, there is substantially no gap between the inner packing body 10 and the partition plate 15 and is filled with a cushioning material sheet. In addition, a cushioning material sheet is buried between the foamed polystyrene case 16, the cold insulation unit 8, and the partition plate 15 as an exterior.

  In the configuration of the refrigerated transport packaging body of the first embodiment shown in FIG. 2, the fourth comparative packaging body has a configuration of the first paperboard case 3 and the first heat insulating case 2 serving as the interior and exterior, and the aluminum foil and the first heat insulating case. The difference is that it is constituted by case 2. That is, in the 4th comparison packing object, the 1st heat insulation case 2 is the structure covered with the aluminum foil.

  FIG. 5 is a graph showing a temperature transition of a first comparison package that is a general refrigerated packaging form using only the cold insulation agent and a second comparison package using the cold insulation unit 8. In FIG. 5, the vertical axis represents temperature [° C.], and the horizontal axis represents storage time [hr] from completion of packing. In FIG. 5, the solid line indicates the outside air temperature, the broken line indicates the internal temperature transition of the first comparison package, and the alternate long and short dash line indicates the internal temperature transition of the second comparison package. Here, the internal temperature of the first comparative package and the second comparative package was used by measuring the temperature of the internal space of the box for storing the product.

  As apparent from the graph of FIG. 5, in the first comparative packing body using only the cooling agent, the internal temperature temporarily decreased to about −4 ° C. On the other hand, in the second comparative package using the cold insulation unit 8, the minimum temperature was 3.5 ° C. without being 2 ° C. or lower. Moreover, the internal temperature transition in the second comparative package body was more gradual in the storage temperature over time than the first comparative package body. However, the holding time of 8 ° C. or less in the second comparative package was about 28 hours from the completion of the package, and did not exceed the target 30 hours.

  FIG. 6 is a graph showing a result of an experiment performed on the third comparative package shown in FIG. 4 and shows a temperature transition compared to the outside air temperature. In FIG. 6, the vertical axis represents temperature [° C.], and the horizontal axis represents storage time [hr] from the completion of packing. In FIG. 6, the solid line indicates the outside air temperature, and the broken line indicates the internal temperature transition of the third comparison package. Here, the internal temperature of the third comparison package was used by measuring the temperature of the internal space of the box for storing the product. In addition, the graph of FIG. 6 has shown the temperature transition in the summer.

  The configuration of the third comparison package is that in which the arrangement of the cold insulation unit 8 and the installation of the partition plate 15 are performed in order to extend the holding time of 8 ° C. or less. However, as shown in the graph of FIG. 6, in the temperature condition where the outside air temperature is high in summer, the internal temperature is greatly affected, and the holding time of 8 ° C. or less is about 23 hours from the completion of the packaging.

  FIG. 7 is a graph showing a temperature transition with respect to the outdoor temperature in summer in the refrigerated transport package and the fourth comparative package of the first embodiment. As described above, the configuration of the fourth comparison package is made of aluminum foil instead of the first paperboard case 3 serving as the interior and exterior as compared with the configuration of the refrigerated transport package of the first embodiment. As is apparent from the graph of FIG. 7, in the summer, the holding time of 8 ° C. or less is extended to about 30 hours in the configuration of the fourth comparative package. In the configuration of the refrigerated transport package of the first embodiment, the holding time within the temperature range of 2 ° C. or more and 8 ° C. or less is further extended to about 33 hours. Further, in the configuration of the refrigerated transport package of the first embodiment, the influence from the outside air temperature is mitigated as compared with the configuration of the fourth comparative package, and the internal temperature is a moderate temperature change.

  In the graph of FIG. 7, the outside air temperature when the temperature transition of the refrigerated transport package of Embodiment 1 is measured is indicated as “outside air temperature 1”, and the outside air when the temperature transition of the fourth comparative packaging body is measured. The temperature is indicated as “outside air temperature 2”. In addition, the internal temperature of the refrigerated transport package and the fourth comparative package of Embodiment 1 was used by measuring the temperature of the internal space of the box that stores the product.

  Further, according to the experiment by the inventors, in the configuration of the refrigerated transport package of Embodiment 1, the holding time in the temperature range of 2 ° C. to 8 ° C. when the outside air temperature changes from 16 ° C. to 30 ° C. is , About 44 hours. Furthermore, in the configuration of the refrigerated transport package of Embodiment 1, for example, even in the initial stage, a situation where the temperature temporarily drops below 0 ° C. did not occur.

  In the refrigerated transport package of the first embodiment, the initial use temperature of the frozen body (first cold insulation agent 13) and the cold storage body (second cold insulation agent 14) constituting the cold insulation unit (8, 9), and the outside air A temperature characteristic table showing the relationship between the temperature and the storage temperature range is prepared in advance based on experiments, and based on the temperature characteristic table, the initial set temperature of the frozen state of the frozen body and the low temperature state of the refrigerated body An initial set temperature may be set.

  Further, in the first embodiment, as the first heat insulating case 2 for storing a product (medicine), a product foamed polystyrene case having a capacity of about 6 liters (180 mm × 220 mm × 155 mm) and disposed inside, a second The heat insulation case 5 has a capacity of about 65 liters (415 mm × 465 mm × 335 mm) and a cold insulation foamed polystyrene case arranged outside, and is refrigerated by the cold insulation unit (8, 9). As long as the heat insulation case 2 has a capacity of 5 to 10 liters and the second heat insulation case 5 has a capacity of 50 to 100 liters, the cold insulation unit (8, 9) used in the first embodiment is used. It is possible to respond.

  As described above, the configuration of the refrigerated transport package of Embodiment 1 has a configuration that greatly reduces the influence of the outside air temperature, and the internal temperature changes gradually even if the outside air temperature changes significantly. It is the structure to do. For this reason, it is possible to carry out highly reliable refrigerated transportation with less burden on transported goods stored, for example, products (pharmaceuticals). In addition, the refrigerated transport package according to Embodiment 1 is made of a commonly used material without using a special cooling agent or a special device, so that it is relatively inexpensive and simple. Thus, it is possible to realize one-way transportation in which the package is discarded only by one refrigerated transportation.

(Embodiment 2)
Hereinafter, the refrigerated transport package according to Embodiment 2 of the present invention will be described in detail with reference to the accompanying drawings. The configuration of the refrigerated transport package of the second embodiment is a configuration in which heat generating means is provided in the configuration of the first embodiment.

  FIG. 8 is a view showing an inner bottom surface of a second paperboard case (corrugated cardboard case) 12 serving as an exterior case in the refrigerated transport packaging body according to the second embodiment of the present invention. The refrigerated transport package of Embodiment 2 also has an internal configuration similar to the internal configuration shown in FIG. That is, the second heat insulating case (cold foam foam case) 5 is accommodated in the second paperboard case (corrugated cardboard case) 12 shown in FIG. However, in the refrigerated transport package of the second embodiment, heat generating means is disposed between the outer bottom surface of the second heat insulating case (cooled foamed polystyrene case) 5 and the inner bottom surface of the second paperboard case 12 serving as the outer case. Has been. As the heat generating means in the refrigerated transport package according to the second embodiment, a warmer 18 is used. For example, a so-called disposable warmer that generates heat using the oxidizing action of iron powder is used.

  As shown in FIG. 8, in the refrigerated transport package of the second embodiment, rectangular spacers 19 are disposed at the four corners of the inner bottom surface of the second paperboard case 12 serving as an exterior case. Is set so as to secure a heat generation space by the warmer 18. As a material of the spacer 19, styrene foam is used. As the disposable body warmer in the second embodiment, “HEAT CHARGER” manufactured by Kowa Co., Ltd. was used.

  The inventor conducted an experiment on the transition between the outside air temperature and the inside temperature under conditions assuming transportation by truck in winter using the refrigerated transportation package of Embodiment 2 having the above-described configuration.

  FIG. 9 is a graph showing a temperature transition during transport in the winter season of the refrigerated transport package according to the second embodiment. In FIG. 9, the vertical axis represents temperature [° C.], and the horizontal axis represents storage time [hr] from completion of packing. In FIG. 9, the solid line indicates the outside air temperature, and the broken line indicates the transition of the bottom surface temperature of the first paperboard case (product cardboard case) 3 in the refrigerated transport packaging body according to the second embodiment. Moreover, in FIG. 9, the dashed-dotted line has shown transition of the bottom face temperature of the internal space of the box which accommodates a product in the refrigerated transport packaging body of Embodiment 2. FIG.

  As is apparent from the graph of FIG. 9, in the winter truck transportation, even if the outside air temperature decreases sharply after the packaging is completed, the temperature of the bottom of the first paperboard case (product cardboard case) 3 in the refrigerated transportation packaging body is The temperature rises to about 19 ° C. due to the heat generated by the heating means (Cairo 18). Thus, even if the temperature of the bottom of the inner first paperboard case 3 rises, in the refrigerated transport packaging body of the second embodiment, the second heat insulating case 5 includes the cold insulation units (8, 9). Since it has a cooling structure, the bottom temperature of the box that houses the product in the first heat insulation case, which is the internal temperature of the refrigerated transport package of Embodiment 2, is within the temperature range of 2 ° C to 8 ° C. It is configured to be held for a certain period. According to the graph shown in FIG. 9, in the refrigerated transport package of the second embodiment, the outside air temperature rapidly decreases from 20 ° C., and the temperature range from 0.9 ° C. to 3.8 ° C. changes severely. Even if it is temperature conditions, the internal temperature of the 1st heat insulation case 2 of the refrigerated transport packaging body of Embodiment 2 is maintained within the temperature range of 2 ° C. to 8 ° C. for at least 9 hours [hr] immediately after packing. Yes.

  The configuration of the refrigerated transport package of the second embodiment has a configuration that greatly reduces the influence of the outside air temperature even in a severe temperature environment in winter, and the internal temperature even if the outside temperature changes significantly. Is a slowly changing configuration. For this reason, the burden with respect to the product (medicine) stored is small, and it becomes possible to perform refrigerated transport with high reliability. In addition, the refrigerated transport package of the second embodiment is configured by a commonly used one without using any special member or special device, so it can be easily produced at a relatively low cost. This makes it possible to produce one-way refrigerated transport in which the package is discarded only by one refrigerated transport.

  Although the refrigerated transport packaging body of the present invention has been described using the first and second embodiments, the refrigerated transport packaging kit of the present invention includes at least a first heat insulating case (product foamed polystyrene case) 2, a first Paperboard case (product corrugated cardboard case) 3, second heat insulation case (cooled foamed polystyrene case) 5, side surface cooler unit (frozen body, refrigerated body) 8, top surface cooler unit (frozen body, refrigerated body) 9, and second paperboard case (Exterior case: Corrugated cardboard case) 12 is configured, and each member is sold as a product before assembly. Further, the refrigerated transport packaging kit of the present invention may include a heat insulating buffer sheet 6 and a top heat insulating sheet (aluminum sheet and heat insulating buffer sheet) 11. Further, the refrigerated transport packaging kit of the present invention may include a cushioning sheet (bubble sheet) 4 and a heat insulating material column (styrofoam column) 7.

  The refrigerated transport packaging kit of the present invention configured as described above can be purchased at a low price without using a special coolant or packing material, and a highly reliable refrigerated transport packaging that can be easily manufactured is assembled. Is possible. The refrigerated transport packaging body assembled in this way is configured to be kept below a freezing point even if the internal temperature of the storage space for storing the transported article is temporary, and can be maintained within a predetermined storage temperature range for a predetermined time. It has the structure where the influence with respect to the change of external temperature was suppressed.

  As described above, as specifically described in the embodiment, the present invention is, for example, a refrigerated transport package used for refrigerated transport of pharmaceuticals, and the temperature of a storage space for storing transported articles is temporarily below freezing point. It is a configuration that can be maintained within a predetermined storage temperature range for a predetermined time, and is not easily affected by changes in the outside air temperature, which is the environmental temperature. Thus, it is possible to provide a refrigerated transport package that can be manufactured at low cost without using any of the above.

  The refrigerated transport package of the present invention has a storage temperature at which goods (pharmaceuticals) are defined by general truck transport even when strict standards are required for transport and storage by GDP (pharmaceutical distribution standards). It is possible to maintain the quality during transportation to ensure the quality of the transported goods and to achieve a significant reduction in transportation cost.

  Although the present invention has been described in each embodiment with a certain degree of detail, these configurations are exemplifications, and the disclosure of these embodiments should change in the details of the configurations. In the present invention, replacement, combination, and change of order of elements in each embodiment can be realized without departing from the scope and spirit of the claimed invention.

  The present invention is used as a transport package used for transporting pharmaceuticals with particularly strict temperature control, and can provide a package that can be easily manufactured with a simple configuration. Become a body.

1 Transportation goods (products)
2 First heat insulation case (Styrofoam case)
2a body 2b lid 2c internal space 3 first paperboard case (product cardboard case)
4 Buffer material sheet (bubble sheet)
5 Second heat insulation case (cooled foamed polystyrene case)
6 Insulation buffer sheet 7 Insulation material pillar (Styrofoam pillar)
8 Side cooler unit 9 Top cooler unit 10 Inner package (product package)
11 Top heat insulation sheet (aluminum sheet and heat insulation buffer sheet)
12 Second paperboard case (exterior case: cardboard case)
13 First cryogen (frozen)
14 Second cold storage agent (refrigerated body)
15 Partition Plate 16 Styrofoam Case 17 Bottom Cooling Unit 18 Cairo (Heat Heating Means: Disposable Cairo)
19 Spacer HA Transported goods holding space HB Cooling unit holding space

Claims (12)

A first heat insulating case for storing and holding a transport article and having heat insulation properties;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
A shock-absorbing cushioning sheet that wraps around the first paperboard case;
A side cold-retaining unit disposed on the four side surfaces of the first paperboard case via the cushioning material sheet and serving as a cooling source for the transported article;
One transport article holding space for holding the inner package body composed of the first heat insulating case, the first paperboard case, and the cushioning material sheet storing the transport article at a substantially central position, and the side cooling unit provided with the first cold storage unit. A second heat-insulating case having four heat-retaining unit holding spaces disposed and held via the cushioning material sheet so as to face the four sides of one paperboard case, and having heat insulation properties;
The inner package body that is disposed on the inner wall surface that forms the transport article holding space and the cold insulation unit holding space in the second heat insulating case, and is housed and held in the transport article holding space, and is stored in the cold insulation unit holding space. A heat-insulating cushion sheet that covers the held side-surface cold-retaining unit and has heat insulation, shock absorption, and flexibility;
A top surface cooling unit that is disposed on the top surface of the inner package covered with the heat insulating cushioning sheet and serves as a cooling source for the transported article;
A top surface heat insulating sheet that covers the top of the top surface cold insulation unit together with the inner package and has heat insulation properties, and a paperboard case that houses the second heat insulation case together with the top surface cold insulation unit and the top surface heat insulation sheet. A corrugated cardboard attached to at least one surface, and a rectangular parallelepiped case,
Each of the side surface cooling unit and the top surface cooling unit is configured by integrating a frozen body and a refrigerated body, and is arranged such that the refrigerated body is interposed between the frozen body and the inner package body. Refrigerated transport packaging.   The frozen body and the refrigerated body in the side surface cooling unit and the top surface cold storage unit are formed of a cryogen having the same melting point, the frozen body is initially used in a frozen state, and the refrigerated body is initially in a low temperature state. A refrigerated transport package according to claim 1 configured for use.   The second heat insulation case is formed of a rectangular parallelepiped, and a space constituted by the transported article holding space and the cold insulation unit holding space is defined by columnar bodies of heat insulating materials formed at four corners in plan view of the rectangular parallelepiped, The refrigerated transport packaging body according to claim 1 or 2, wherein a space between adjacent columnar bodies becomes the cold-retaining unit holding space.   The initial use temperature of the frozen body is in a temperature range of -20 ° C to 0 ° C, and the initial use temperature of the refrigerated body is in a temperature range of 0 ° C to 5 ° C. The refrigerated transport package according to item.   The frozen body and the refrigeration body in the side surface cooling unit and the top surface cooling unit have the same shape and are integrated, and each of the integrated body is a cushioning material bag body having shock absorption and flexibility. The refrigerated transport package according to any one of claims 1 to 4, which is sealed inside.   The internal space of the second heat insulation case is configured not to dispose a cooling source between the bottom surface of the inner package and the inner bottom surface of the second heat insulation case. The refrigerated transport package described in 1.   The refrigerated transport packaging body according to any one of claims 1 to 6, wherein the heat insulating buffer sheet is formed of a highly foamed polyethylene sheet, and the top heat insulating sheet is an aluminum sheet.   The heat generation space is secured by providing a spacer between the outer bottom surface of the second heat insulation case and the inner bottom surface of the exterior case, and heat generation means is provided in the heat generation space. The refrigerated transport package according to item.   The refrigerated transport package according to claim 8, wherein the heat generating means is a disposable body warmer. A first heat insulation case having heat insulation properties for storing and holding a transport article;
A paperboard case for housing the first heat insulation case, wherein the first paperboard case is configured in a rectangular parallelepiped shape by attaching a corrugated cardboard on at least one surface;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the paperboard case on the four sides of the first paperboard case. Side cooling unit that serves as a cooling source for articles,
One transport article holding space for holding an inner packing body including the first heat insulating case and the first paperboard case containing the transported article in a substantially central position, and the side cold-retaining unit for the four sides of the first paperboard case. A second heat-insulating case having four heat-retaining unit holding spaces that are arranged so as to oppose each other and are stored and held;
The transport, wherein the frozen body and the refrigerated body are integrated and arranged so that the refrigerated body is interposed between the frozen body and the inner package body on the top surface of the inner package body. A top surface cooling unit that serves as a cooling source for the article, and a paperboard case that houses the second heat insulating case together with the top surface cooling unit, and is configured in a rectangular parallelepiped shape with corrugated cardboard attached to at least one surface A refrigerated transport packaging kit including an outer case. The inner package body disposed in the transport article holding space, arranged on the inner wall surface forming the transport article holding space and the cold insulation unit holding space in the second heat insulating case, and the cold insulation unit holding space A heat insulating cushioning sheet having heat insulating property, shock absorbing property and flexibility for covering the side surface cold insulating unit stored and held; and heat insulating property for covering an upper portion of the top surface cold insulating unit together with the inner packing body. The refrigerated transport packaging kit according to claim 10, comprising a top heat insulation sheet having   The frozen body and the refrigerated body in the side surface cooling unit and the top surface cold storage unit are formed of a cryogen having the same melting point, the frozen body is initially used in a frozen state, and the refrigerated body is initially in a low temperature state. The refrigerated transport packaging kit according to claim 10 configured to be used.

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