JP2019134837A - Guide wire - Google Patents

Abstract

To provide a guide wire capable of further improving transmission in a living body lumen.SOLUTION: A guide wire 100 comprises: a long-state core member 110 having flexibility; and a tip member 120 having a wire 121 wound to cover at least a part of a tip part of the core member 110 and a plurality of rotors 122 inserted into the wire and rotatable to the wire.SELECTED DRAWING: Figure 5

Description

  The present invention relates to a guide wire.

  In recent years, a technique using a catheter such as a balloon catheter has been performed for the treatment of a stenosis occurring in a body lumen such as a blood vessel. For example, in general PCI (Percutaneous Coronary Intervention), an operator places a balloon catheter balloon along a preceding guide wire in a stenosis formed in the coronary artery. Then, the surgeon expands the balloon to expand the stenosis, thereby improving blood flow on the peripheral side of the stenosis.

  As described above, the guide wire preceding the catheter may not pass through the stenosis part or may be stuck without passing through the stenosis part when the blocking rate of the stenosis part is high. In order to solve such a problem, Patent Document 1 below has a cross-sectional shape that reduces the contact area between the long core shaft and the blood vessel wall, and a coil wound around the tip of the core shaft. And a guide wire having a body. According to the guide wire described in Patent Document 1 below, since the contact area between the coil body and the blood vessel wall is reduced, the sliding frictional force between the coil body and the blood vessel wall is reduced, and the guide wire in the blood vessel is reduced. Passability can be improved.

JP2015-93122A

  However, the guide wire described in Patent Document 1 merely reduces the contact area between the coil body and the blood vessel wall, and a sliding frictional force is generated between the coil body and the blood vessel wall. For this reason, there is a limit to the improvement of the passage of the guide wire in the living body lumen only by reducing the contact area between the coil body and the blood vessel wall as in Patent Document 1.

  The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a guide wire that can further improve the passage through a living body lumen.

  A guide wire according to the present invention that achieves the above object includes a long core member having flexibility, a wire wound so as to cover at least a part of a tip portion of the core member, and the wire And a tip member provided with a plurality of rotating bodies that are rotatable with respect to the wire.

  According to the guide wire according to the present invention, when the surgeon moves the distal end portion of the guide wire in a narrow region of the living body lumen such as the stenosis, the rotating body in contact with the inner wall of the living body forming the living body lumen is It moves while rolling against the inner wall of the living body. At this time, a rolling friction force is generated between the tip member and the inner wall of the living body, but the rolling friction force is smaller than the sliding friction force. Therefore, according to the present invention, compared with a guide wire that does not include a rotating body and the wire moves in a sliding manner with respect to the inner wall of the living body while directly contacting the inner wall of the living body, the passage through the living body lumen is more improved. A further improved guide wire can be provided.

It is a fragmentary sectional view showing roughly the guide wire concerning this embodiment. It is a perspective view showing roughly a tip member with which a guide wire concerning this embodiment is provided. It is an arrow view from the arrow 3A direction of FIG. It is a partial expanded sectional view of FIG. 3A. It is an arrow view from the arrow 4A direction of FIG. 2, Comprising: It is a figure which shows the state which the rotary bodies adjacent in the longitudinal direction of a core member are contacting. It is a figure which shows the state which the rotary bodies adjacent to the longitudinal direction of a core member have spaced apart with respect to FIG. 4A. It is a figure which shows a mode that the guide wire which concerns on this embodiment has passed the constriction part. It is a figure which shows the front-end | tip member which concerns on the modification 1, Comprising: It is a figure corresponding to FIG. 4A. It is a figure which shows the front-end | tip member which concerns on the modification 2, Comprising: It is a figure which shows a mode that the front-end | tip member has passed the constriction part. It is a figure which shows the front-end | tip member which concerns on the modification 2, Comprising: It is a figure which shows a mode that the front-end | tip member has passed the narrower part narrower than FIG. 7A. It is a figure which shows the front-end | tip member which concerns on the modification 3, Comprising: It is a figure corresponding to FIG. It is an arrow line view from the arrow 8B direction of FIG. 8A.

  Hereinafter, embodiments of the present invention will be described with reference to the accompanying drawings. In the description of the drawings, the same elements are denoted by the same reference numerals, and redundant description is omitted. In addition, the dimensional ratios in the drawings are exaggerated for convenience of explanation, and may be different from the actual ratios.

  FIG. 1 is a diagram illustrating an overall configuration of a guide wire 100 according to the present embodiment. FIGS. 2-4B is a figure where it uses for description of each part of 100 which concerns on this embodiment.

  The guide wire 100 will be briefly described with reference to FIG. 1. An elongated core member 110 (core wire) having flexibility, a tip member 120 that covers the tip of the core member 110, and the tip member 120 as a core member. And a fixing member 130 that is fixed to 110. Hereinafter, each part of the guide wire 100 will be described in detail.

  In the description of the present specification, a direction in which the core member 110 extends in a state in which the core member 110 is straightened is defined as a “longitudinal direction X”. Further, the side of the guide wire 100 that is introduced into the living body is defined as the distal end side (distal side, left side in FIG. 1), and the end side opposite to the distal end side is the proximal end side (proximal side, FIG. (Right side). Further, a portion including a certain range in the longitudinal direction X from the distal end (the most distal end) is defined as a “distal end portion”, and a portion including a certain range in the longitudinal direction X from the proximal end (most proximal end) is defined as “the proximal end portion”. Is defined. 4A and 4B show only the wire 121 and the rotating body 122 on the near side in FIG. 2, and the wire 121 and the rotating body 122 on the back side in FIG. 2 are omitted.

(Core member)
The core member 110 includes a first core portion 111 disposed on the distal end side in the longitudinal direction X, and a second core portion 112 disposed on the proximal end side of the first core portion 111 and joined to the first core portion 111. It is equipped with. Hereinafter, each part of the core member 110 will be described in detail.

  First, the first core unit 111 will be described.

  In the present embodiment, the first core portion 111 has a flat plate portion 111a disposed on the distal end side, a tapered portion 111b extending from the flat plate portion 111a to the proximal end side, and substantially constant from the tapered portion 111b to the proximal end side. An outer diameter constant portion 111c extending at an outer diameter, a tapered portion 111d extending from the outer diameter constant portion 111c to the proximal end side, an outer diameter constant portion 111e extending from the tapered portion 111d to the proximal end side with a substantially constant outer diameter, Is provided. In addition, the shape of the 1st core part 111 is not limited to the shape to show in figure. For example, the first core portion 111 may be formed with a constant outer shape (a constant outer diameter) from the distal end side to the proximal end side.

  Although the constituent material of the 1st core part 111 is not specifically limited, For example, superelastic alloys, such as a Ni-Ti type alloy, stainless steel, a cobalt type alloy, etc. can be used.

  Next, the second core unit 112 will be described.

  The second core part 112 is connected to the base end of the constant outer diameter part 111 e of the first core part 111 via the connection part 113. Although the 1st core part 111 and the 2nd core part 112 are not specifically limited, For example, it can connect by methods, such as welding and brazing. The core member 110 may be composed of a single continuous member without being composed of a plurality of members like the first core portion 111 and the second core portion 112.

  Although the constituent material of the 2nd core part 112 will not be specifically limited if it differs from the constituent material of the 1st core part 111, For example, super elastic alloys, such as a Ni-Ti type alloy, stainless steel, and a cobalt type alloy are used. be able to.

  A coating layer 141 is provided on the outer surface of the base end portion of the first core portion 111, the outer surface of the connection portion 113, and the outer surface of the second core portion 112. The constituent material of the covering layer 141 is preferably a material that can reduce the sliding frictional force received from the inner wall W of the living body forming the living body lumen. Examples of such materials include, but are not limited to, polyolefins such as polyethylene and polypropylene, polyvinyl chloride, polyesters (PET, PBT, etc.), polyamides, polyimides, polyurethanes, polystyrenes, polycarbonates, silicone resins, fluorine resins ( PTFE, ETFE, etc.) or a composite material thereof. The constituent material of the covering layer 141 is a portion provided on the outer surface of the base end portion of the first core portion 111 and the outer surface of the second core portion 112, and a portion provided on the outer surface of the connection portion 113. May be different.

(Tip member)
The tip member 120 includes a wire 121 wound so as to cover at least a part of the tip of the core member 110, and a plurality of rotating bodies 122 that are inserted into the wire 121 and rotatable with respect to the wire 121. Prepare. Hereinafter, each part of the tip member 120 will be described in detail.

  First, the wire 121 will be described.

  As shown in FIGS. 1 and 2, the wire 121 is wound in a spiral shape so as to cover at least a part of the first core portion 111 with the first core portion 111 as a center. The wire 121 is separated from the first core portion 111. In addition, in this embodiment, although the wire 121 is wound by the substantially constant diameter along the longitudinal direction X of the core member 110, the diameter at the time of winding the wire 121 does not need to be constant.

  In the present embodiment, the wire 121 has a substantially circular cross-sectional shape as shown in FIG. Therefore, the rotating body 122 can rotate smoothly with respect to the wire 121.

  The outer diameter r1 of the wire 121 is preferably 0.03 to 0.08 mm. The outer diameter r1 of the wire 121 is more preferably 0.05 to 0.06 mm. By setting the outer diameter r1 of the wire 121 within the above range, the maximum length L of the tip member 120 along the direction perpendicular to the longitudinal direction X of the core member 110 is maintained while maintaining sufficient tensile strength of the wire 121. The maximum radial width L) of the tip member 120 can be kept small. Note that the cross-sectional shape of the wire 121 is not particularly limited as long as the rotating body 122 is rotatable with respect to the wire 121. That is, the cross-sectional shape of the wire 121 is not particularly limited as long as a gap is generated between the through-hole 123 of the rotating body 122 through which the wire 121 is inserted and the wire 121. For example, the cross-sectional shape of the wire 121 may be an ellipse or the like.

  In addition, it is preferable that the maximum width L in the radial direction of the tip member 120 is 0.05 mm to 0.5 mm. Further, the maximum width L in the radial direction of the tip member 120 is more preferably 0.3 to 0.4 mm. By setting the maximum radial width L of the distal end member 120 in the above range, the distal end member 120 passes through the lumen of a catheter such as a guiding catheter or a living body lumen while ensuring the rigidity of the distal end member 120. The property can be kept suitable.

  Although the constituent material of the wire 121 is not specifically limited, For example, radiopaque (X-ray opaque) materials, such as metals, such as gold | metal | money, platinum, tungsten, a tantalum, and an alloy containing these, or Ni- A radiation-transmitting material such as a superelastic alloy such as a Ti alloy, stainless steel, or a cobalt alloy can be used.

  Next, the rotating body 122 will be described.

  As shown in FIG. 3B, each rotating body 122 is provided with a through hole 123 into which the wire 121 can be inserted. Although the through-hole 123 is not specifically limited, For example, it can form using methods, such as cutting, laser processing, and electrical discharge machining.

  Each rotating body 122 is rotatable with respect to the wire 121 in a state where the wire 121 is inserted through the through hole 123 of each rotating body 122 (that is, can be rotated around the wire 121). Therefore, as shown in FIG. 5, when the surgeon moves the distal end portion of the guide wire 100 in the stenosis N (the movement direction is indicated by an arrow a in the figure), the rotating body 122 is in contact with the inner wall W of the stenosis N. Moves while rolling with respect to the inner wall W of the constriction N. At this time, a rolling friction force is generated between the tip member 120 and the inner wall W of the narrowed portion N, but the rolling friction force is smaller than the sliding friction force. Therefore, compared to a guide wire that does not include a rotating body and the wire moves while sliding in direct contact with the inner wall of the living body, the passage of the guide wire 100 through the living body lumen is further improved. Can be improved. Further, since the plurality of rotating bodies 122 are in contact with the inner wall W of the living body, the guide wire 100 can reduce the contact area with the inner wall W of the living body as compared with the case where the wire is in direct contact with the inner wall W of the living body. it can. Therefore, the passage of the guide wire 100 through the living body lumen can be further improved. As a result, it is possible to suppress the tip portion of the guide wire 100 from being stacked in a narrow region of the living body lumen such as the stenosis N. At this time, as shown in FIG. 3B, the center of the through hole 123 becomes the rotation axis Y of the rotating body 122.

  In this embodiment, each rotating body 122 is configured by providing a through-hole 123 into which a wire 121 can be inserted into a sphere. That is, each rotating body 122 has a spherical surface in the present embodiment. Therefore, the contact area between each rotating body 122 and the inner wall W of the living body can be reduced as compared with the case where the rotating body is configured by a cylinder, an ellipsoid, or the like described later. Therefore, it is possible to further improve the passage of the guide wire 100 through the living body lumen and further suppress the tip portion of the guide wire 100 from being stacked in a narrow region of the living body lumen such as the constriction N.

  The maximum outer diameter r2 (see FIGS. 1 and 3A, hereinafter referred to simply as “the outer diameter r2 of the rotating body 122”) in the direction orthogonal to the rotation axis Y of the rotating body 122 is 0.05 to 0.10 mm. Is preferred. The outer diameter r2 of the rotating body 122 is more preferably 0.07 to 0.08 mm. By setting the outer diameter r2 of the rotating body 122 within the above range, the visibility of the tip member 120 under radiation projection is ensured (when the rotating body 122 is made of a radiopaque material described later) ), The radial maximum width L of the tip member 120 can be kept small. The shape of the rotator 122 is not particularly limited as long as the rotator 122 can rotate with respect to the wire when the rotator 122 contacts the inner wall W of the living body. However, it is preferable that the rotating body 122 has a circular cross section in a cross section orthogonal to the rotation axis Y so as to roll more smoothly with respect to the inner wall W of the living body. Examples of the rotating body having a circular cross section include those having a through-hole through which the wire 121 can be inserted at the center of a cylinder, a spheroid, or the like.

  As shown in FIG. 3A, the rotating bodies 122 adjacent in the winding direction R1 of the wire 121 are in contact with each other. Therefore, it can suppress that each rotary body 122 moves to winding direction R1 of the wire 121 (namely, moving on the wire 121). If the rotating body 122 is slidable in the winding direction R1 of the wire 121, the rotating body 122 slides in the winding direction R1 of the wire 121 when the rotating body 122 comes into contact with the inner wall W of the living body ( That is, there is a possibility of sliding on the wire 121. And thereby, between the living body side surface of the rotating body 122 (outer surface of the rotating body 122) and the inner wall W of the living body, and the surface of the rotating body 122 on the through hole 123 side (inner surface of the rotating body 122). There is a possibility that a sliding frictional force is generated between the wire 121 and the wire 121. Therefore, as in the present embodiment, by suppressing the movement of the rotating body 122 in the winding direction R1 of the wire 121, the generation of the sliding friction force between the rotating body 122 and the inner wall W of the living body is suppressed, and the guide The passability of the wire 100 can be further improved. However, the rotating bodies 122 adjacent in the winding direction R1 of the wire 121 may be separated from each other. Even if the rotating body 122 slides on the inner wall W of the living body and some sliding friction force is generated, if the rotating body 122 can rotate with respect to the wire 121, the guide wire 100 moves through the living body lumen. When moving, the rotating body 122 moves while rolling with respect to the inner wall W of the living body, and the passage of the guide wire 100 through the living body lumen can be improved to some extent.

  As shown in FIG. 4A, the wire 121 includes a plurality of winding portions 121a, 121b, and 121c that go around the periphery of the first core portion. And the rotary body 122a inserted in one winding part 121a of the adjacent winding parts 121a, 121b, 121c is in contact with the rotary bodies 122b, 122c inserted in the other winding parts 121b, 121c. doing. That is, in the present embodiment, the rotating bodies 122a, 122b, 122c adjacent to each other in the longitudinal direction X of the core member 110 are in contact with each other.

  As a first effect of the above configuration, it is possible to suppress the movement of the rotating body 122 in the longitudinal direction X of the core member 110. If the movement of the rotating body 122 in the longitudinal direction X of the core member 110 is not suppressed, the rotating body 122 slides in the longitudinal direction X of the core member 110 when the rotating body 122 contacts the inner wall W of the living body. It may move and receive a sliding frictional force from the inner wall W of the living body. Therefore, like this embodiment, by suppressing the movement of the rotating body 122 in the longitudinal direction X of the core member 110, the generation of the sliding friction force between the rotating body 122 and the inner wall W of the living body is suppressed, and the guide The passability of the wire 100 in the living body lumen can be further improved.

  A second effect of the above configuration is to reduce the angle θ1 formed by the longitudinal direction X of the core member 110 and the rotational direction R2 of each rotating body 122. Hereinafter, this point will be described with reference to FIGS. 4A and 4B. As shown in FIG. 4A, “A rotating body 122a inserted into one winding part 121a among adjacent winding parts 121a, 121b, 121c is a rotating body inserted into the other winding parts 121b, 121c. "It is in contact with 122b, 122c" means that the pitch P between the winding portions of the wire rod 121 is short, and the angle θ2 formed by the plane T perpendicular to the longitudinal direction X of the core member 110 and the winding direction R1 of the wire rod 121. (Hereinafter simply referred to as “spiral angle θ2”) is small. The smaller the spiral angle θ2, the smaller the angle θ1 formed by the rotation direction R2 of the rotating body 122 and the longitudinal direction X. Since the traveling direction of the guide wire 100 coincides with the longitudinal direction X on the distal end side of the guide wire 100, the smaller the angle θ1, the smaller the difference between the rotational direction R2 of the rotating body 122 and the traveling direction of the guide wire 100. Become.

  On the other hand, as shown in FIG. 4B, of the adjacent winding parts 121a, 121b, 121c, the rotating body 122a inserted into one winding part 121a is inserted into the other winding parts 121b, 121c. The further away from the rotating bodies 122b and 122c, the larger the pitch P between the winding portions of the wire 121, and the larger the spiral angle θ2. As the spiral angle θ2 increases, the angle θ1 formed by the rotation direction R2 of the rotating body 122 and the longitudinal direction X increases. The greater the angle θ1, the greater the difference between the rotational direction R2 of the rotating body 122 and the traveling direction of the guide wire 100, and the sliding frictional force that the rotating body 122 receives from the inner wall W of the living body increases. Thus, in the present embodiment, since the angle θ1 is small, the difference between the rotation direction R2 of the rotating body 122 and the traveling direction of the guide wire 100 can be reduced. Therefore, the passability of the guide wire 100 can be further improved.

  However, in another embodiment, a rotating body 122 inserted into one winding part 121a in the wire 121 is inserted into other winding parts 121b and 121c adjacent in the longitudinal direction X of the core member 110. It may be separated from 122. Even if the rotating bodies 122a, 122b, and 122c are separated from each other, if the rotating bodies 122a, 122b, and 122c can rotate with respect to the wire 121, the guide wire 100 moves through the living body lumen. Each rotating body 122a, 122b, 122c moves while rolling with respect to the inner wall W of the living body, and can improve the passage of the guide wire 100 through the living body lumen to some extent.

  The spiral angle θ2 is uniquely determined by the maximum radial width L of the tip member 120, the outer diameter r2 of the rotating body, and the pitch P. For example, when the maximum length L of the tip member 120 in the direction orthogonal to the longitudinal direction X is 0.345 mm, the outer diameter r2 of the rotating body 122 is 0.075 mm, and the pitch P is 0.075 mm, the spiral angle θ2 is about 5 Degree.

  The constituent material of each rotating body 122 is not particularly limited, but, for example, a radiopaque material such as a metal such as gold, platinum, tungsten, and tantalum, and an alloy including these metals, or a Ni-Ti alloy or the like Radiation transmissive materials such as superelastic alloys, metals such as stainless steel and cobalt alloys, and polymer materials such as polytetrafluoroethylene, polyurethane, silicone resin, and polyamide can be used.

  A coating layer (not shown) is provided on the outer surface of each rotating body 122. The constituent material of the coating layer is not particularly limited. For example, a cellulose polymer material, a polyethylene oxide polymer material, a maleic anhydride polymer material (for example, methyl vinyl ether-maleic anhydride copolymer, etc. Maleic anhydride copolymers), acrylamide polymer substances (for example, polyacrylamide, glycidyl methacrylate-dimethylacrylamide block copolymers), hydrophilic materials such as water-soluble nylon, polyvinyl alcohol, and polyvinylpyrrolidone can be used. . Thereby, high lubricity can be imparted to the tip member 120.

(Fixing member)
As shown in FIG. 1, the fixing member 130 includes a first fixing portion 131 that fixes the distal end portion of the distal end member 120 to the first core portion 111, and a proximal end portion of the distal end member 120 as the first core portion 111. A second fixing portion 132 that is fixed to the second fixing portion 132.

  Each of the fixing portions 131 and 132 can be made of, for example, solder, brazing material, adhesive, or the like. It is preferable that the distal end portion of the first fixing portion 131 has a rounded shape as illustrated in consideration of the influence on the inner wall W of the living body when coming into contact with the inner wall W of the living body.

  A coating layer 142 is provided on the outer surface of each of the fixing portions 131 and 132. As a constituent material of the covering layer 142, the same constituent material as that of the covering layer of the rotating body 122 can be used.

(Production method)
Next, an example of a method for manufacturing the guide wire 100 will be described.

  When manufacturing the tip member 120, a plurality of rotating bodies 122 are inserted through the wire 121, and a pair of stoppers 124a and 124b (see FIG. 2) are attached so that the plurality of rotating bodies are sandwiched between the wires 121. The pair of stoppers 124 a and 124 b prevent the rotating body 122 from falling off the wire 121 during the manufacture of the guide wire 100. Next, the wire 121 to which the plurality of rotating bodies 122 are attached is wound along the peripheral surface of the core metal having a predetermined shape. Thereby, the tip member 120 as shown in FIG. 2 can be obtained.

  Next, as shown in FIG. 1, the obtained tip member 120 is disposed so as to cover at least a part of the tip portion of the core member 110, thereby forming the fixing member 130. 110 is fixed. Thereby, a guide wire 100 as shown in FIG. 1 can be obtained. However, the manufacturing method of the guide wire 100 is not limited to the above method. For example, the rotating body 122 may be inserted through the wire 121 after the wire 121 is wound.

(Example of use)
Next, with reference to FIG. 5, the method of using the guide wire 100 according to the present embodiment will be described by taking as an example a procedure for expanding a stenotic portion N in which a blood vessel (biological lumen) is narrowed by a balloon catheter (not shown). To do.

  The surgeon inserts the guide wire 100 to the vicinity of the stenosis N in the blood vessel through an introducer (not shown) and a guiding catheter (not shown).

  Next, as shown in FIG. 5, the surgeon pushes the guide wire 100 into the living body and inserts the distal end portion of the guide wire 100 into the narrowed portion N. At this time, the rotating body 122 in contact with the inner wall W of the narrowed portion N advances while rolling with respect to the inner wall W of the narrowed portion N. At this time, a rolling friction force is generated between the tip member and the inner wall W of the narrowed portion N. The rolling friction force is smaller than the sliding friction force. Therefore, it is possible to further improve the passability of the guide wire 100 in the blood vessel and to suppress the tip portion of the guide wire 100 from being stacked in the stenosis N.

  Next, the surgeon places the balloon catheter balloon in the stenosis N along the guide wire 100. Next, the surgeon expands the balloon and pushes the stenosis N. As a result, the stenosis portion is expanded and blood flow on the peripheral side of the stenosis portion is improved.

  Next, the operator contracts the balloon and removes the balloon catheter and the guide wire 100 from the living body.

  As described above, the usage example of the guide wire 100 has been described, but the technique of applying the guide wire 100 is not limited to the above technique. For example, the catheter introduced into the living body along the guide wire 100 is not limited to a balloon catheter, and may be a balloon catheter for stent delivery or the like.

  As described above, the guide wire 100 according to the above-described embodiment includes the long core member 110 having flexibility, and the wire 121 wound so as to cover at least a part of the distal end portion of the core member 110. And a tip member 120 provided with a plurality of rotating bodies 122 that are inserted into the wire 121 and are rotatable with respect to the wire 121.

  Therefore, when the surgeon moves the distal end portion of the guide wire 100 in a narrow region such as the stenosis N in the living body lumen, the rotating body 122 in contact with the inner wall W of the living body forming the living body lumen becomes the inner wall W of the living body. Move while rolling against. At this time, a rolling frictional force is generated between the tip member 120 and the inner wall W of the living body, but the rolling frictional force is smaller than the sliding frictional force. Therefore, the guide wire 100 is further improved in passage through the living body lumen as compared with a guide wire that does not include a rotating body and the wire rod moves while sliding on the inner wall of the living body while sliding. Can be provided.

  Further, the rotating bodies 122 adjacent in the winding direction R1 of the wire 121 are in contact with each other. Therefore, it is possible to suppress the sliding body 122 from sliding in the winding direction R1 of the wire 121 while being in contact with the inner wall W of the living body and generating a sliding friction force with the inner wall W of the living body. As a result, the passability of the guide wire 100 can be further improved.

  The wire 121 includes winding portions 121a, 121b, and 121c adjacent to each other in the longitudinal direction X of the core member 110, and is inserted into one winding portion 121a among the adjacent winding portions 121a, 121b, and 121c. The rotating body 122a is in contact with the rotating bodies 122b and 122c inserted through the other winding parts 121b and 121c. Therefore, it is possible to suppress the sliding body 122 from sliding in the longitudinal direction X of the core member 110 while being in contact with the inner wall W of the living body and generating a sliding frictional force with the inner wall W of the living body. Further, by reducing the angle θ1 formed by the rotation direction R2 of the rotating body 122 and the longitudinal direction X of the core member 110, the rotating body 122 can roll in the traveling direction of the guide wire 100. As a result, the passability of the guide wire 100 can be further improved.

  The rotating body 122 has a spherical surface. Therefore, the contact area between each rotating body 122 and the inner wall W of the living body can be reduced as compared with the case where each rotating body is configured by a cylinder, an ellipsoid, or the like. As a result, the passability of the guide wire 100 can be further improved.

(Modification 1)
FIG. 6 is a view showing a tip member 420 according to the first modification.

  The tip member 420 according to Modification 1 is different from the tip member 120 according to the above-described embodiment in the arrangement of the rotating body 422. Hereinafter, the tip member 420 according to Modification 1 will be described in detail. In addition, about the structure similar to the said embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

  In the tip member 420 according to the first modification, unlike the tip member 120 according to the above embodiment, the plurality of rotating bodies 422 are not arranged linearly in the longitudinal direction X of the core member 110. In the first modification, the plurality of rotating bodies 422 include other winding portions 121 b and 121 c in which one rotating body 422 a inserted into one winding portion 121 a in the wire 121 is adjacent in the longitudinal direction X of the core member 110. Are arranged so as to be in contact with the four rotating bodies 422b, 422c, 422d, and 422e inserted through the. Therefore, compared with the said embodiment, the space S between the rotary bodies 422 becomes narrow. As a result, the displacement of each rotating body 422 can be further suppressed as compared with the above embodiment.

  The arrangement of the rotating body 422 as in Modification 1 can be realized by appropriately adjusting the dimensions of the rotating body 422, the winding diameter of the wire 121, the pitch P of the wire 121, and the like.

(Modification 2)
7A and 7B are views showing a tip member 220 according to the second modification.

  The tip member 220 according to Modification 2 includes the tip member 120 according to the above-described embodiment in that the tip member 220 includes at least two types of rotating bodies 222 and 223 having different maximum lengths r3 and r4 along the direction orthogonal to the rotation axis Y. Is different. Hereinafter, the tip member 220 according to Modification 2 will be described in detail. In addition, about the structure similar to the said embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

  The tip member 220 has a plurality of first rotating bodies 222 and a plurality of second rotating bodies 223.

  The maximum length r4 along the direction orthogonal to the rotation axis Y of the second rotator 223 (the outer diameter r4 of the second rotator 223) is the maximum length along the direction orthogonal to the rotation axis Y of the first rotator 222. It is shorter than r3 (the outer diameter r3 of the first rotating body 223). Therefore, when the surgeon moves the distal end portion of the guide wire 100 in the stenosis N in the living body lumen, as shown in FIG. 7A, the first rotating body 222 protruding outward in the radial direction is the inner wall W of the living body. And moves while rolling against the inner wall W of the living body. At this time, since the second rotating body 223 is retracted inward in the radial direction, it is difficult to contact the inner wall W of the living body. Therefore, the contact area between the tip member 220 and the living body inner wall W can be reduced as compared with the tip member 120 according to the above embodiment. As a result, the passability of the guide wire 100 in the living body lumen can be further improved. As shown in FIG. 7B, when the surgeon moves the guide wire 100 within a narrower living body lumen, not only the first rotating body 222 but also the second rotating body 223 comes into contact with the inner wall W of the living body. Rotate. Therefore, the passage of the guide wire 100 can be suitably maintained even in a narrower body lumen.

  The first rotator 222 is disposed in the winding direction R <b> 1 of the wire 121, and the second rotator 223 is disposed so as to be sandwiched between the first rotators 222. Therefore, the first rotating body 222 can be brought into contact with the inner wall W of the living body before the second rotating body 223 comes into contact with the inner wall W of the living body. However, the arrangement of the first rotating body 222 and the second rotating body 223 is not particularly limited.

  As described above, the tip member 220 according to Modification 2 includes at least two or more types of rotating bodies 222 and 223 having different maximum lengths r3 and r4 along a direction orthogonal to the rotation axis Y. When the surgeon moves the guide wire 100 within the living body lumen, the relatively long rotating body 222 having the maximum length r4 along the direction orthogonal to the rotation axis Y comes into contact with the inner wall W of the living body. The relatively short rotating body 223 having the maximum length r3 along the direction orthogonal to the rotation axis Y is difficult to contact the inner wall W of the living body. Therefore, compared with the tip member 120 according to the above embodiment, the contact area between the tip member 220 and the inner wall W of the living body can be reduced, and the passage of the guide wire 100 in the living body lumen can be further improved. Further, when the surgeon moves the guide wire 100 in a narrower living body lumen, not only the rotating body 222 but also the rotating body 223 contacts the inner wall W of the living body and rotates. Therefore, the passability of the guide wire 100 in a narrower biological lumen can be suitably maintained.

(Modification 3)
8A and 8B are views showing a tip member 320 according to the third modification.

  The tip member 320 according to Modification 3 is different from the tip member 120 according to the above-described embodiment in that the wire 321 is not spirally wound. Hereinafter, the tip member 320 according to Modification 3 will be described in detail. In addition, about the structure similar to the said embodiment, the same code | symbol is attached | subjected and the description is abbreviate | omitted.

  The tip member 320 includes a wire 321 that is wound so as to cover at least a part of the tip of the core member 110.

  The wire rod 321 is bent from the annular portion 322 and is bent from the annular portion 322 on the plane perpendicular to the longitudinal direction X of the first core portion 111, and the longitudinal direction X of the first core portion 111. The connecting portions 323 extending in the direction are alternately wound. In the present embodiment, the plurality of annular portions 322 have the same diameter, but the diameters of the plurality of annular portions 322 may not be the same.

  Each annular portion 322 passes through the plurality of rotating bodies 122. Since the winding direction R1 of each annular part 322 is orthogonal to the longitudinal direction X of the first core part 111, the rotational direction R2 of each rotating body 122 is the longitudinal direction of the first core part 111 as shown in FIG. 7B. Matches X. That is, the rotation direction of each rotating body 122 matches the traveling direction of the guide wire 100. Therefore, each rotating body 122 can rotate in a direction that matches the traveling direction of the guide wire 100. As a result, the passability of the guide wire 100 through the living body lumen can be further improved.

  Each connecting portion 323 does not pass through the rotating body 122.

  As shown in FIG. 8A, the rotating bodies 122 adjacent to each other in the winding direction R1 of the annular portions 322 are in contact with each other. Each connecting portion 323 also has a function as a stopper that restricts the plurality of rotating bodies 122 on each annular portion 322 from moving in the winding direction R1. Therefore, it can suppress that the some rotary body 122 moves to winding direction R1 of the annular part 322. FIG. Note that the rotating bodies 122 adjacent in the winding direction R1 of the annular portion 322 may be separated from each other.

  Further, as shown in FIG. 8B, the rotating body 122a inserted into one annular portion 322a of the annular portions 322a, 322b, and 322c adjacent in the longitudinal direction X is inserted into the other annular portions 322b and 322c. The rotating bodies 122b and 122c are in contact with each other. That is, the rotating bodies 122a, 122b, 122c adjacent to each other in the longitudinal direction X of the core member 110 are in contact with each other. Therefore, the movement of the rotating body 122 in the longitudinal direction X of the core member 110 can be suppressed. As a result, the generation of sliding frictional force between the rotating body 122 and the inner wall W of the living body can be suppressed, and the passage of the guide wire 100 through the living body lumen can be further improved.

  As described above, the wire 321 according to the modification 3 includes the annular portion 322 that is wound on the plane perpendicular to the longitudinal direction X of the first core portion 111 and through which the plurality of rotating bodies 122 are inserted. Since the rotation direction R2 of each rotating body 122 can be made to coincide with the traveling direction of the guide wire 100, the passage of the guide wire 100 in the living body lumen is further improved as compared with the distal end member 120 according to the embodiment. Can be improved.

  As mentioned above, although the guide wire which concerns on this invention was demonstrated through embodiment, this invention is not limited only to each structure demonstrated, It can change suitably based on description of a claim.

  For example, the rotating body should just be provided in at least one part of the wire. Specifically, for example, the wire is configured of a first wire wound so as to cover at least a part of the distal end portion of the core member, and a material different from the first wire, and the proximal end of the first wire And the rotating body may be provided only on the first wire or only on the second wire. If the distal end portion of the guide wire cannot pass through the narrowed portion or the like, the proximal end side cannot pass through the narrowed portion or the like. Therefore, when the rotating body is provided in at least a part of the wire, the rotating body is the first wire rod. It is preferable that it is provided at the tip of the wire. In the above case, the first wire may be made of, for example, a radiopaque material, and the second wire may be made of, for example, a radiopaque material.

  Moreover, for example, the rotating bodies adjacent in the winding direction of the wire may be separated from each other. In this case, stoppers may be provided at both ends of each rotating body in order to prevent each rotating body from sliding in the winding direction of the wire. Thereby, while suppressing the sliding movement of each rotating body in the winding direction of the wire, the number of rotating bodies used can be reduced, and the contact area between the tip member and the inner wall of the living body can be reduced. At this time, it is preferable to apply a coating layer made of a hydrophilic material or the like to the exposed portion of the wire.

100 guide wire,
110 core member,
120, 220, 230 tip member,
121,321 wire,
122, 222, 223 rotating body,
R1 winding direction,
R2 direction of rotation,
X longitudinal direction of the core member,
Y The rotation axis of the rotating body.

Claims (5)

A long core member having flexibility; and
A wire rod wound so as to cover at least a part of the tip end portion of the core member, and a tip member provided with a plurality of rotating bodies that are inserted into the wire rod and rotatable with respect to the wire rod, Guide wire.   The guide wire according to claim 1, wherein the rotating bodies adjacent in the winding direction of the wire are in contact with each other. The wire includes a winding portion adjacent to the longitudinal direction of the core member,
The rotating body inserted into one winding part among the adjacent winding parts is in contact with the rotating body inserted into another winding part. Guide wire as described.   The guide wire according to claim 1, wherein the rotating body includes a spherical surface.   The guide wire according to any one of claims 1 to 4, wherein the tip member includes at least two or more types of the rotating bodies having different maximum lengths along a direction orthogonal to the rotation axis.