JP2019054991A - Analysis apparatus and analysis system - Google Patents

Abstract

To provide an analysis apparatus capable of comparing the dynamic analysis results of moving images captured by different imaging devices.SOLUTION: An analysis apparatus 3 receives moving images from a plurality of different imaging devices 1a-1c and displays the received moving images and analysis results of the moving images, the analysis apparatus including a control unit 31 for correcting the moving images or the analysis results of the moving images using an amount of move of a structure S contained in the moving images.SELECTED DRAWING: Figure 1

Description

  The present invention relates to an analysis apparatus and an analysis system.

In contrast to conventional still image shooting using a semiconductor image sensor such as an FPD (Flat Panel Detector) and diagnosis based on the shot still image, in recent years, moving image shooting of a subject using FPD or the like and moving image obtained thereby Analysis systems that analyze and provide diagnosis are known.
The analysis system is an imaging device that captures a moving image, a console for controlling the imaging device or displaying a captured moving image for confirmation, and analysis of a plurality of frame images obtained by imaging. And an analysis device for performing the display and a display device for displaying the analysis result.

For example, in Patent Document 1, a feature amount related to a density change between a plurality of frame images and a feature amount related to a form change between a plurality of frame images of a dynamic image obtained by photographing the dynamics of the chest are calculated, and a feature related to the density change is calculated. An analysis system for calculating a feature quantity related to a lung ventilation function or a cardiac function based on a ratio of a quantity and a feature quantity related to a morphological change is described.
Patent Document 2 exemplifies a case where the imaging apparatus that performs the moving image imaging is a magnetic resonance imaging apparatus (hereinafter referred to as an MRI (Magnetic Resonance Imaging) apparatus).

  At the time of moving image shooting, the FPD generates each frame image as an electrical signal corresponding to the radiation intensity applied to the elements arranged in a matrix. Depending on the system, after the generated image is logarithmically converted on the FPD or the console, a moving image obtained by converting the density gradation with an LUT or the like is displayed on the monitor so that the structure in the subject can be observed more easily.

  In dynamic analysis, various calculation processes are performed between pixel values included in multiple frames that make up a moving image obtained in this way, so the density value of the moving image that is the analysis source and the signal value of the analysis result of the moving image are It is known that it greatly affects the results of dynamic analysis.

  Note that “moving image shooting” and “moving image” here are not limited to normal moving image shooting and moving images performed using a video camera or the like. It is a concept including dynamic photography that should be said. That is, the moving image shooting in the case of the present invention includes dynamic shooting in which a plurality of frames of radiographic images are shot in a moving image continuously in time, and includes a frame rate in normal moving image shooting (for example, 30 frames per second). There are many cases where the frame rate is smaller than that of a frame and the like, and there are cases where there is a restriction on the shooting time. Also, in normal moving image shooting, it is usually configured to display the captured moving image in real time. However, in the case of moving image shooting such as the dynamic shooting described above, the real time property of the moving image display is In many cases, it is not guaranteed, and the moving image is not displayed (or cannot be displayed) at the same time as shooting.

For example, in dynamic imaging, radiation may be emitted in a pulse form from a radiation irradiating device, but may be emitted in a state where a low dose of radiation is continuously emitted. The radiographic image capturing apparatus is usually configured to read out image data in synchronization with the timing of radiation irradiation from the radiation irradiation apparatus in the former case, and in the latter case, Shooting is performed by appropriately adjusting the timing of reading image data.
In the present invention, any of the above cases can be included in “moving image shooting”, and a plurality of frames of radiographic images taken in a moving image continuously in time are referred to as “moving images”. The radiation image is referred to as a “frame image”.

JP 2017-18681 A Japanese Patent No. 5556174

  By the way, as a radiation imaging apparatus for a relatively large scale facility such as a hospital, a plurality of types of imaging apparatuses such as a general imaging apparatus, an angiographic apparatus and an X-ray TV including a fluoroscopic function using FPD or the like, as well as CT and MRI May be introduced. Each device is equipped with a radiation detector such as an FPD, an electric circuit related to the operation of the radiation detector, and a moving image generated under the influence of the control method, etc. For this purpose, the image processing such as gradation processing is performed independently, and the characteristics of the moving image finally obtained by each apparatus are different.

  For this reason, for example, in an analysis device that performs dynamic analysis using parameters that are optimal for a moving image obtained by a photographing device with known characteristics of the generated moving image, the characteristics of the generated moving image are unknown. Even if dynamic analysis is performed by the same method on moving images obtained by different imaging devices, the analysis result as expected is not usually obtained. Therefore, there are many cases where correct comparison results cannot be obtained even if the analysis results of the moving images obtained by the respective photographing devices are compared and used for diagnosis or the like.

  The present invention has been made in view of the above-described problems, and an object of the present invention is to provide an analysis apparatus that can compare dynamic analysis results of moving images captured by different imaging apparatuses.

In order to solve the above problem, the analysis device of the present invention is:
An analysis device that receives moving images from a plurality of different photographing devices and displays the received moving images and analysis results of the moving images,
The image processing apparatus includes a correction unit that corrects the moving image or the analysis result of the moving image using a moving amount of the structure included in the moving image.

In order to solve the above problem, the analysis system of the present invention is:
A standard imaging device capable of capturing moving images;
A shooting device capable of shooting a moving image and different from the reference shooting device;
The analysis device according to any one of claims 1 to 5,
It is characterized by providing.

  ADVANTAGE OF THE INVENTION According to this invention, it becomes possible to compare the dynamic analysis result of the moving image image | photographed with the several different imaging device.

It is a figure showing the analysis system containing the analysis apparatus which concerns on this embodiment. It is a figure showing the example of the input-output characteristic with respect to the radiation of the moving image for every imaging device. It is a figure showing an example of the correlation of the moving amount | distance of the structure contained in a moving image, and the density | concentration average value of a moving image. It is a figure showing an example of the correlation of the movement amount of the structure contained in a moving image, and the signal average value of the analysis result of a moving image. It is a figure which shows an example of the physique corrected prediction curve in the case of correct | amending the estimated value of the density | concentration average value of a moving image with the physique of a to-be-photographed object.

Hereinafter, an embodiment of an analysis apparatus according to the present invention will be described with reference to the drawings.
However, the embodiments described below are provided with various technically preferable limitations for carrying out the present invention. However, the technical scope of the present invention is not limited to the following embodiments and illustrated examples. Absent.

[Positioning of analysis device and overall configuration of analysis system]
The analysis device according to the present embodiment constitutes a part of an analysis system, receives moving images from a plurality of different imaging devices, and displays the received moving images and analysis results of the moving images.
First, as a premise, the overall configuration of the analysis system assumed in this embodiment will be described with reference to FIG.

The analysis system includes a plurality of different imaging devices capable of capturing a moving image, and an analysis device capable of performing dynamic analysis on the moving images captured by the plurality of different imaging devices.
Specifically, as shown in FIG. 1, the analysis system 100 according to the present embodiment includes a plurality of different imaging devices 1 (imaging devices 1 a, 1 b, 1 c) and an analysis device 3, such as a LAN (Local Area Network). And connected via a communication network NT.
The plurality of imaging devices 1 include, for example, an imaging device 1 provided in a general imaging room (not shown), an imaging console 2 for controlling the imaging device 1, an imaging device 1 provided in an emergency room (not shown), A photographing console 2 for controlling the photographing device 1, a photographing device 1 configured to be portable, a portable photographing console 2 for controlling the photographing device 1, and the like.
Although FIG. 1 shows an example in which three imaging devices 1 (imaging devices 1a, 1b, and 1c) are provided, the number of imaging devices 1 is not limited to three and may be two or more. That's fine. Furthermore, when there is no particular distinction between the plurality of photographing devices 1, they are simply referred to as photographing devices 1.
In the present embodiment, the analysis device 3 is a diagnostic console that generates and displays an image or the like (moving image or moving image analysis result) used for diagnosis.
Each device constituting the analysis system 100 conforms to the DICOM (Digital Image and Communications in Medicine) standard, and communication between the devices is performed according to DICOM.
Note that the analysis device 3 and the imaging device 1 need not always be connected to the communication network NT.

In the present embodiment, the imaging apparatus 1a operates under imaging control by the imaging console 2, and setting conditions such as a tube for irradiating radiation, FPD image reading conditions, and the like are known in advance on the analysis system 100 side. It is assumed that the characteristics of the moving image obtained by the photographing apparatus 1a are known in the analysis apparatus 3.
For this reason, in this embodiment, the imaging device 1a is referred to as a “reference imaging device”, and a moving image captured by the imaging device 1a is referred to as a “reference moving image D” whose moving image characteristics are known.
Further, the photographing devices 1b and 1c, which are photographing devices other than the photographing device 1a, are referred to as “photographing devices different from the reference photographing device”, and the moving images photographed by the photographing devices 1b and 1c are denoted as “moving image d”. .
Note that the reference moving image D and the moving image d are a set of image data of each frame image, and in the following, the wording of the reference moving image D or the moving image d is a meaning of a set of image data of each frame image. In some cases, it may be used, but it may be used in the sense of the image data of one frame image of each frame image constituting the moving image.

[Configuration of the photographing apparatus 1]
As described above, the photographing apparatus 1 is capable of photographing a moving image.
In the present embodiment, “moving image” imaging means that a subject is repeatedly irradiated with radiation such as X-rays at a predetermined time interval (pulse irradiation) or continuously at a low dose rate. This is a dynamic imaging in which a plurality of images showing the dynamics of a subject are acquired by irradiating (continuous irradiation). That is, the “moving image” in the present embodiment means a series of a plurality of images showing the dynamics of the subject obtained by such shooting. Each of a plurality of images constituting the moving image is referred to as a frame image.
The dynamics of a subject (biological body) that can be photographed by taking a “moving image” include, for example, the dynamics of a human body having a periodicity (cycle) such as pulmonary expansion and contraction due to respiratory motion, heart pulsation, etc. There is.
In the following embodiments, a case where dynamic imaging of the chest (particularly the lung field) is performed by pulse irradiation will be described as an example.

In the present embodiment, for example, the imaging apparatus 1a is a radiographic imaging apparatus including a radiation source 11, a radiation irradiation control device 12, a radiation detection unit 13, a reading control device 14, and the like as shown in FIG.
As will be described later, the radiation irradiation control device 12 and the radiation detection unit 13 of the imaging device 1 are connected to the imaging console 2, and the radiation irradiation control device 12 is based on the radiation irradiation conditions input from the imaging console 2. Radiation imaging is performed by controlling the radiation source 11. In addition, the radiation detection unit 13 controls the switching unit of each pixel based on the image reading condition input from the imaging console 2, and acquires image data by reading the electric signal accumulated in each pixel, The acquired image data of the frame image is output to the imaging console 2.

In FIG. 1, the detailed configuration is shown only for the photographing device 1a, but the photographing devices 1b and 1c have the same configuration.
As the imaging apparatus 1, CT, MRI, or the like can be applied in addition to the radiographic imaging apparatus. Further, it may be an X-ray television or the like.
For example, different types of devices may be mixed in the analysis system such that the imaging device 1a and the imaging device 1b are radiographic imaging devices and the imaging device 1c is an X-ray television.
Note that the above-mentioned “different imaging devices” means that the imaging devices are different individuals, and the imaging devices 1a, 1b, and 1c are all the same type of devices (for example, all radiographic imaging devices). It does not exclude certain cases. Even in the same type of imaging apparatus, individual differences occur depending on the setting and the like, and therefore there is a significance of performing processing in the analysis apparatus and analysis system described later.

The radiation source 11 is disposed at a position facing the radiation detection unit 13 with the subject M (subject) in between, and irradiates the subject M with radiation (X-rays) under the control of the radiation irradiation control device 12.
The radiation irradiation control device 12 is connected to the imaging console 2 and controls the radiation source 11 based on the radiation irradiation conditions input from the imaging console 2 to perform radiation imaging. The radiation irradiation conditions input from the imaging console 2 are, for example, pulse rate, pulse width, pulse interval, number of imaging frames per imaging, X-ray tube current value, X-ray tube voltage value, additional filter type, etc. It is. The pulse rate is the number of times of radiation irradiation per second, and matches the frame rate described later. The pulse width is a radiation irradiation time per one irradiation. The pulse interval is a time from the start of one radiation irradiation to the start of the next radiation irradiation, and coincides with a frame interval described later.

The radiation detection unit 13 includes a semiconductor image sensor such as an FPD (Flat Panel Detector). The FPD has, for example, a glass substrate or the like, detects radiation that has been irradiated from the radiation source 11 and transmitted through at least the subject M at a predetermined position on the substrate according to its intensity, and detects the detected radiation as an electrical signal. A plurality of detection elements (pixels) converted and stored in a matrix are arranged in a matrix. Each pixel includes a switching unit such as a TFT (Thin Film Transistor). The FPD includes an indirect conversion type in which X-rays are converted into electric signals by a photoelectric conversion element via a scintillator, and a direct conversion type in which X-rays are directly converted into electric signals, either of which may be used.
The radiation detection unit 13 is provided to face the radiation source 11 with the subject M interposed therebetween.

The reading control device 14 is connected to the imaging console 2. The reading control device 14 controls the switching unit of each pixel of the radiation detection unit 13 based on the image reading condition input from the imaging console 2 to switch the reading of the electrical signal accumulated in each pixel. Then, the image data is acquired by reading the electrical signal accumulated in the radiation detection unit 13. This image data is a frame image. The pixel signal value of the frame image represents a density value. Then, the reading control device 14 outputs the acquired frame image to the photographing console 2. The image reading conditions are, for example, a frame rate, a frame interval, a pixel size, an image size (matrix size), and the like. The frame rate is the number of frame images acquired per second and matches the pulse rate. The frame interval is the time from the start of one frame image acquisition operation to the start of the next frame image acquisition operation, and coincides with the pulse interval.
Here, the radiation irradiation control device 12 and the reading control device 14 are connected to each other, and exchange synchronization signals to synchronize the radiation irradiation operation and the image reading operation.

[Configuration of the shooting console 2]
The imaging console 2 outputs radiation irradiation conditions and image reading conditions to the imaging apparatus 1 to control radiation imaging and radiographic image reading operations by the imaging apparatus 1, and also captures dynamic images acquired by the imaging apparatus 1. The image is displayed for confirming whether the image is suitable for confirmation of positioning or diagnosis by a photographer.
As shown in FIG. 1, the imaging console 2 includes a control unit 21, a storage unit 22, an operation unit 23, a display unit 24, and a communication unit 25, and each unit is connected by a bus 26.
In FIG. 1, the detailed configuration is shown only for the imaging console 2 that controls the imaging device 1a, but the imaging console 2 that controls the imaging devices 1b and 1c also has the same configuration.

  The control unit 21 includes a CPU (Central Processing Unit), a RAM (Random Access Memory), and the like. The CPU of the control unit 21 reads the system program and various processing programs stored in the storage unit 22 in accordance with the operation of the operation unit 23, expands them in the RAM, and performs shooting control processing described later according to the expanded programs. Various processes including the beginning are executed to centrally control the operation of each part of the imaging console 2 and the radiation irradiation operation and the reading operation of the imaging apparatus 1.

The storage unit 22 is configured by a nonvolatile semiconductor memory, a hard disk, or the like. The storage unit 22 stores various programs executed by the control unit 21 and data such as parameters necessary for execution of processing by the programs or processing results. For example, the storage unit 22 stores a program for executing processing related to shooting control.
Various programs are stored in the form of readable program code, and the control unit 21 sequentially executes operations according to the program code.
In addition, the storage unit 22 stores imaging conditions (radiation irradiation conditions and image reading conditions) corresponding to the type of imaging and the region to be inspected (that is, the imaging region, here the chest).
The radiation irradiation conditions are, for example, an X-ray tube current value, an X-ray tube voltage value, a filter type, a SID (Source to Image-receptor Distance), a pulse rate at the time of moving image shooting, a pulse width, a pulse interval, and the like. The image reading conditions are, for example, a pixel size, an image size (matrix size), a frame rate at the time of moving image shooting, a frame interval, and the like. The frame rate matches the pulse rate.
Further, the storage unit 22 stores imaging order information transmitted from an unillustrated RIS (Radiology Information System) or the like. The imaging order information includes patient information, examination information (examination ID, examination target part (here, chest), analysis type (for example, ventilation analysis, pulmonary blood flow analysis, measurement of maximum ventilation), and data attributes ( Emergency, outpatient general, ward follow-up) etc.).

  The operation unit 23 includes a keyboard having a cursor key, numeric input keys, various function keys, and the like, and a pointing device such as a mouse. The control unit 23 controls an instruction signal input by key operation or mouse operation on the keyboard. To 21. In addition, the operation unit 23 may include a touch panel on the display screen of the display unit 24. In this case, the operation unit 23 outputs an instruction signal input via the touch panel to the control unit 21.

The display unit 24 is configured by a monitor such as an LCD (Liquid Crystal Display) or a CRT (Cathode Ray Tube), and displays an input instruction, data, or the like from the operation unit 23 in accordance with an instruction of a display signal input from the control unit 21. To do.
In addition, the image captured by the image capturing apparatus 1 may be displayed so that the positioning can be confirmed.

  The communication unit 25 includes a LAN adapter, a modem, a TA (Terminal Adapter), and the like, and controls data transmission / reception with each device connected to the communication network NT.

[Configuration of Analysis Device 3]
The analysis device 3 can perform dynamic analysis on moving images taken by different photographing devices 1.
As shown in FIG. 1, the analysis device 3 includes a control unit 31, a storage unit 32, an operation unit 33, a display unit 34, and a communication unit 35, and each unit is connected by a bus 36.
In the present embodiment, the analysis device 3 receives a moving image from the imaging console 2, analyzes the received moving image, performs image processing, and the like, and displays a display unit 34 (described later) or an external device. This is an image processing apparatus that displays an analysis result or the like on a display device (not shown) and performs reanalysis, and is a diagnostic console that supports diagnosis by a doctor.
In the present embodiment, the analysis device 3 performs chest dynamics analysis based on the chest moving image transmitted from the imaging console 2.

In the analysis system 100 of the present embodiment, moving images photographed by the photographing devices 1a, 1b, and 1c are sent to the analyzing device 3 from the photographing console 2 connected to the three photographing devices 1a, 1b, and 1c, respectively. It is supposed to be.
In the following, a moving image captured by the reference image capturing device (that is, the image capturing device 1a) is referred to as a “reference moving image D”, and is different from the reference image capturing device (that is, the image capturing device 1a). A moving image photographed by the apparatus (that is, the photographing devices 1b and 1c) is referred to as “moving image d”.

Although FIG. 1 illustrates the case where the analysis device 3 that is a diagnostic console and the above-described imaging console 2 are separate devices, the configuration of the analysis system 100 is not limited to this.
For example, the analysis system 100 may be configured by connecting the dual-purpose device having functions as the imaging console 2 and the diagnostic console and the imaging device 1 via the communication network NT. In this case, the combined device functions as an analysis device.

The control unit 31 includes a CPU (Central Processing Unit), a RAM (Random Access Memory), and the like. The CPU of the control unit 31 reads out the system program and various processing programs stored in the storage unit 32 in accordance with the operation of the operation unit 33 and expands them in the RAM, and performs diagnosis support processing according to the expanded programs. Various processes including the beginning are executed to centrally control the operation of each part of the analysis device 3. The control unit 31 functions as a region-of-interest setting unit, a concentration waveform generation unit, a correction unit, and a setting condition input unit.
Specifically, the control unit 31 executes moving image reception processing and analysis processing in cooperation with a program. Furthermore, the control unit 31 displays the analysis result on the display unit 34 or an external display device (not shown) in response to a request from the operation unit 33 or the like.
In particular, in the present embodiment, the control unit 31 of the analysis device 3 uses the moving amount of the structure S (see FIG. 3) included in the moving images received from the plurality of different imaging devices 1 to use the moving image or the moving image. It functions as a correction means for correcting the analysis result.
Specifically, the control unit 31 as the correction unit moves the structure S included in the moving image (that is, the reference moving image D) captured by the reference imaging device (that is, the imaging device 1a) ( For example, using a correlation between the movement amount of the diaphragm (amount of change in position) and a signal value (amount of change in density in FIG. 3) included in the moving image or the analysis result of the moving image, the reference imaging device is A moving image (that is, moving image d) photographed by different photographing devices (that is, 1b and 1c) or an analysis result of the moving image is corrected.
Here, the “structure S” included in the moving image is, for example, a structure S constituting the human body that is a subject, such as a lung, a diaphragm, or a heart, and its position or outer edge according to the biological activity of the subject. Changes (moves).
Note that details of the correction processing by the control unit 31 of the analysis apparatus 3 of the present embodiment will be described later.

  The storage unit 32 is configured by a nonvolatile semiconductor memory, a hard disk, or the like. The storage unit 32 stores various programs including a program for executing diagnosis support processing by the control unit 31, parameters necessary for execution of processing by the program, or data such as processing results. These various programs are stored in the form of readable program codes, and the control unit 31 sequentially executes operations according to the program codes.

  Further, in the storage unit 32, a moving image captured in the past includes identification ID, patient information (subject attribute information. For example, patient ID, patient (subject) name, height, weight, age, sex, etc.), examination information. (For example, examination ID, examination date, examination target part (here, chest), etc.) are stored in association with each other. In addition, the storage unit 32 includes patient information, examination information, and status (for example, progress status during reception, analysis processing, analysis completion, etc.) related to each moving image that has been received from the imaging console 2. List information is stored. Further, the storage unit 32 stores the analysis result in association with the moving image.

  The operation unit 33 includes a keyboard having cursor keys, numeric input keys, various function keys, and the like, and a pointing device such as a mouse. The operation unit 33 receives an instruction signal input by a key operation or a mouse operation on the keyboard by the user. Output to the control unit 31. The operation unit 33 may include a touch panel on the display screen of the display unit 34, and in this case, an instruction signal input via the touch panel is output to the control unit 31.

  The display unit 34 is configured by a monitor such as an LCD (Liquid Crystal Display) or a CRT (Cathode Ray Tube), and performs various displays according to instructions of a display signal input from the control unit 31.

The display unit 34 may have a function as a display device for displaying the analysis result, and the display device for displaying the analysis result is provided as a separate device from the analysis device 3. May be.
As an external display device for displaying the analysis result, for example, an electronic medical record installed in a doctor's examination room, an interpretation terminal device installed in an interpretation room of an interpretation doctor, an operating room, etc. A terminal device (console) or the like which is prepared by the radiologist and referred to by a surgeon who performs surgery is assumed. When the display device is provided separately from the analysis device 3 in this way, the analysis result or the like is transmitted from the analysis device 3 to the display device. In this case, when a parameter adjustment instruction or the like is input from the operation unit of the display device that has received the analysis result, the input instruction content is transmitted to the analysis device 3 side, and the analysis device 3 is adjusted according to the instruction. Perform re-analysis with parameters.

  The communication unit 35 includes a LAN adapter, a modem, a TA, and the like, and controls data transmission / reception with each device connected to the communication network NT.

[About correction processing in analyzer]
As described above, the control unit 31 as correction means in the analysis apparatus 3 of the present embodiment calculates the amount of movement of the structure S included in the moving image and the signal value included in the moving image or the analysis result of the moving image. Using the correlation, the moving image or the analysis result of the moving image is corrected.
In the present embodiment, the analysis device 3 includes a moving image (that is, a reference moving image D) of a reference photographing device 1 (for example, the photographing device 1a) and a photographing device 1 (for example, a reference photographing device 1). The moving images (that is, the moving images d) of the photographing devices 1b and 1c) are transmitted, and the control unit 31 moves the moving images (for example, the photographing device 1a) taken as a reference (moving images (for example, the photographing device 1a)). In other words, using a correlation between the moving amount of the structure S included in the reference moving image D) and the signal value included in the moving image or the analysis result of the moving image, the shooting is different from the shooting device 1 serving as a reference. A moving image (that is, moving image d) photographed by the device 1 (for example, the photographing devices 1b and 1c) or a moving image analysis result is corrected.
As described above, in the analysis device 3, the moving amount of the structure S obtained by the reference imaging device 1 (for example, the imaging device 1 a) and the signal value included in the moving image or the analysis result of the moving image. The correlation can be used to correct a moving image of a photographing apparatus 1 (for example, the photographing apparatuses 1b and 1c) different from the reference photographing apparatus 1 and the analysis result of the moving image. By using it, it is also possible to correct the moving image of the imaging device 1 (for example, the imaging device 1a) itself serving as a reference and the analysis result of the moving image with respect to the movement amount of the structure S. This means that if the conditions (for example, X-ray irradiation conditions and environmental factors) at the time of obtaining the correlation are positive, there are variations in conditions that occur at each imaging (for example, differences in X-ray irradiation conditions and noise effects). It is effective to exclude from moving images and moving image analysis results.

Here, when correction is performed on the moving image itself, the “signal value” is the density average value in the region of interest R (ROI, analysis target region, see FIG. 3) in the moving image or the amount of change in the density average value. means.
When correction is performed on the analysis result of the moving image, the “signal value” is the signal average value in the region of interest R (ROI, analysis target region) in the analysis result of the moving image or the amount of change in the signal average value. means.
When the structure S (for example, lung, diaphragm, heart, etc.) in the human body moves due to the biological activity of the subject, the surrounding organs and the like also change with a certain degree of correlation with the structure S.
For example, when the diaphragm as the structure S moves up and down, the lungs expand and contract with the respiratory movement synchronized therewith. Therefore, when the region of interest R is a lung field, the concentration average value in the region of interest R changes.
The observation point of the movement amount of the “structure S” may be an average movement amount obtained by integrally capturing the structure S, or may be an individual point after the structure S is divided into a plurality of regions. It may be the amount of movement of the area. Further, the above-mentioned “region of interest R” may indicate the entire analysis target region (for example, lung field), or may indicate individual regions after the analysis target region is divided into a plurality of regions.
When the density average value in the region of interest R changes in the moving image itself (original moving image), the signal value of the analysis result obtained when the moving image is analyzed also changes accordingly. .
The same effect can be obtained by performing correction by the control unit 31 on the moving image itself (original moving image) or on the analysis result after analyzing the moving image. Then, both of the above cases shall be included.

When a moving image is captured by a plurality of different imaging devices 1, the density change of the region of interest R in the moving image captured by each imaging device 1 is a signal output characteristic with respect to radiation input for each imaging device (modality) 1. Differences occur due to differences in input / output characteristics.
For this reason, the analysis results of moving images cannot be compared with each other as they are.
Such a problem may occur not only between different types of modalities but also between the same type of modalities because input / output characteristics may differ due to differences in installation conditions or the like.

In general, in an analysis apparatus or an analysis system that handles still images or moving images corresponding to a plurality of photographing apparatuses 1a, 1b, and 1c, the appearance of an image finally displayed on a display screen is adjusted for diagnosis. Can be compared.
On the other hand, in the dynamic analysis performed by the analysis device 3 in the present embodiment, the time axis change amount in the region of interest R (ROI, analysis target region) in the moving images acquired from the plurality of imaging devices 1a, 1b, 1c. Need to understand and compare.
However, for example, between moving images acquired from imaging devices 1a, 1b, and 1c having different input / output characteristics for radiation (that is, characteristics of output (concentration) with respect to input (dose of irradiated radiation x)) are temporarily the same. Even if a moving image is obtained by shooting the subject under the same shooting conditions, when each frame image in each moving image is animated in time series, the region of interest R (ROI, analysis target region) The amount of change in the time axis cannot be grasped correctly, and even if these are compared, a correct analysis result cannot be obtained.
In the present embodiment, the control unit 31 serving as a correction unit includes a human body structure S (for example, a lung or a human body) included in a moving image captured by a certain imaging device 1 (in this embodiment, a reference imaging device 1a). The correlation (association) between the movement amount of the diaphragm and the outer edge of the heart) and the signal value included in the analysis result of the moving image and the concentration average value of the region of interest R of the moving image is acquired and used. A moving image captured by a photographing device 1 (for example, photographing devices 1b and 1c) different from the reference photographing device 1a or an analysis result of the moving image is corrected.
Thereby, it becomes possible to compare the analysis results of moving images acquired from a plurality of imaging devices (modalities) 1 including different types.

It should be noted that the object to be subjected to the correction processing of the moving image and the analysis result of the moving image is the moving image d captured by the photographing devices 1b and 1c different from the photographing device 1a that captures the reference moving image (reference moving image D). It is not limited to the analysis result, and it may be a moving image (reference moving image D) taken by the photographing apparatus 1a or an analysis result thereof, both of the moving image d and the reference moving image D, or the moving image d. Both the analysis result and the analysis result of the moving image D may be subject to correction processing.
Hereinafter, a case where correction is performed on the moving image itself and a case where correction is performed on the analysis result of the moving image will be described in detail.

<When correction is performed on the moving image itself>
When the correction is performed on the moving image itself, the control unit 31 serving as a correcting unit corrects the structure S (for example, the diaphragm) included in the moving image of the reference imaging device 1 (the imaging device 1a in this embodiment). Using the correlation between the amount of movement and the average value of the density value in the region of interest R in the moving image of the reference imaging device 1a (this is called the density average value) or the amount of change in the density average value, The moving amount of the structure S included in the moving image of the imaging device 1 (in this embodiment, the imaging devices 1b and 1c) different from the reference imaging device 1a and the region of interest in the moving images of the different imaging devices 1b and 1c A concentration average value in R or an estimated value obtained by estimating a change amount of the concentration average value is obtained.
Then, a correction formula is obtained from the difference between the estimated value and the density average value in the region of interest R actually obtained from the moving images of the different imaging devices 1b and 1c or the amount of change in the density average value, and the correction formula Is applied to correct all pixel data of moving images of the different photographing apparatuses 1b and 1c.

FIG. 2 shows input / output characteristics of the imaging apparatuses 1a, 1b, and 1c when the horizontal axis represents input (X dose) and the vertical axis represents output (concentration). In FIG. 2, “C1a” indicates the input / output characteristics of the moving image captured by the imaging apparatus 1a, “C1b” indicates the input / output characteristics of the moving image captured by the imaging apparatus 1b, and “C1c” indicates the imaging apparatus. The input / output characteristics of the moving image photographed in 1c are shown.
For example, when the input / output characteristics of a moving image (reference moving image D) captured by the reference image capturing device 1a is represented by a curve as indicated by “C1a”, the image is captured by the image capturing devices 1b and 1c, and is unique. When gradation processing by LUT is performed, the input / output characteristics of the moving image d are different from the input / output characteristics “C1a” of the moving image (reference moving image D) captured by the image capturing apparatus 1a. A curve as shown as “C1c” may be drawn.

  For example, in the example shown in FIG. 2, when the concentration (output) in the same X-ray dose (input) range (see A in the figure) is seen, the imaging apparatus 1 a has a moving image (reference moving image) as indicated by “C1a”. Although the density (output) of the image D) is a relatively small value, the fluctuation range appears relatively large (see B in the figure). On the other hand, in the photographing apparatuses 1b and 1c, as indicated by “C1b” and “C1c”, the density (output) of the moving image d becomes a larger value than the density (output) of the reference moving image D, but fluctuates. The range appears relatively small (see B in the figure). As described above, the input / output characteristics of the moving image d are different for each of the photographing apparatuses 1a, 1b, and 1c.

FIG. 3 shows a case where a moving image is obtained by photographing the chest of the subject M under the same photographing conditions with a photographing device 1a as a reference and a photographing device 1 (for example, photographing devices 1b and 1c) different from the reference photographing device 1a. The movement amount of the structure S contained in each frame which comprises each moving image of this, and the time series change of the density | concentration average value in each frame in each moving image are shown.
In FIG. 3, the graph which shows the time-sequential change of the moving amount | distance of the structure S contained in a moving image is shown in the right middle stage. In the middle graph, the horizontal axis represents time t, and the vertical axis represents the position of the structure S.
As shown on the left side of FIG. 3, in the present embodiment, the chest moving image captured by the imaging apparatus 1 includes a lung field as the region of interest R and a diaphragm as the structure S. In the graph in the middle of FIG. 3, the position (movement amount) of the diaphragm included in the reference moving image D captured by the reference imaging device 1a is indicated by a solid line, and the imaging device 1 (for example, different from the reference imaging device 1a) The position (movement amount) of the diaphragm included in the moving image d photographed by the photographing apparatuses 1b and 1c) is indicated by a broken line.

In FIG. 3, on the lower side of the middle graph, the density average value (Ave.) in the region of interest R of each frame in the moving image (reference moving image D) captured by the reference image capturing apparatus 1a. Are arranged in a time-series manner (Da to De in FIG. 3), and the time-series change of the density average value of each pixel is shown by a solid line graph at the bottom. In this graph, the horizontal axis is time t, and the vertical axis is the average value (Ave.) of the concentration of the region of interest R.
Also, in FIG. 3, on the upper side of the middle graph, in the region of interest R of each frame in the moving image d photographed by the photographing device 1 (for example, the photographing devices 1b and 1c) different from the reference photographing device 1a. The density average values (Ave.) of the pixels are schematically arranged in time series (da to de in FIG. 3), and the time series change of the density average value of each pixel is shown as a solid line graph at the top. In this graph, the horizontal axis is time t, and the vertical axis is the average value (Ave.) of the concentration of the region of interest R.

As shown in FIG. 3, the density average value (Ave.) in the region of interest R in each frame of the moving image captured by the reference image capturing device 1a and the moving image captured by the reference image capturing device 1a. When the position of the structure S (diaphragm here) falls between the movement amount of the included structure S (diaphragm here), the average density value in the region of interest R increases (that is, the image becomes dark and black). ).
This is because, for example, when the position of the diaphragm is lowered by breathing, the entire lung is stretched and the alveolar walls that block radiation are thinned, and the transmittance of radiation is increased.

When correcting the moving image itself, the control unit 31 serving as a correcting unit is interested in the position and amount of movement of the structure S (for example, the diaphragm) in the moving image (original moving image) captured by the reference imaging apparatus 1a. A moving image photographed by a photographing device 1 (for example, photographing devices 1b, 1c) different from the reference photographing device 1a using a correlation with an average density value in the region R (for example, lung field) and a change amount of density. An average value of density in the region of interest R (for example, lung field) and an expected value of density change are obtained from the position and movement amount of the structure S (for example, diaphragm) in the image (original moving image). At the top on the right side of FIG. 3, a prediction curve representing a time-series change of the predicted value is indicated by a broken line.
Furthermore, the control unit 31 actually performs a region of interest R (for example, lung field) in a moving image (original moving image) captured by the imaging device 1 (for example, the imaging devices 1b and 1c) different from the reference imaging device 1a. The average density value and the actual measurement value of the amount of change in density (shown by the solid line in the top graph on the right side of FIG. 3) are obtained, the difference between this actual measurement value and the expected value is obtained, and the correction formula is calculated from this difference. To derive.
Then, the control unit 31 applies this correction formula to all pixel data of the moving image (original moving image) d captured by the image capturing device 1 (for example, the image capturing devices 1b and 1c) different from the reference image capturing device 1a. Thus, the correction is performed so that the characteristics of the image are the same as those of the moving image (original moving image) D photographed by the reference photographing apparatus 1a.

  As described above, the moving image d obtained from the image capturing device 1 (for example, the image capturing devices 1b and 1c) is equivalent to the input / output characteristics of the moving image (reference moving image D) captured by the reference image capturing device 1a. By correcting the characteristics of the moving image, the moving image (reference moving image D) captured by the reference image capturing device 1a and the moving images obtained from the image capturing devices 1b and 1c are subjected to dynamic analysis in the analysis device 3. Even when d is mixed, it is possible to perform a dynamic analysis by appropriately comparing these. This makes it possible to obtain an appropriate analysis result that contributes to diagnosis.

<When correction is performed on the analysis result of a moving image>
When correction is performed on the analysis result of the moving image, the control unit 31 serving as a correction unit includes a structure S (for example, a diaphragm) included in the moving image of the reference imaging device 1 (the imaging device 1a in the present embodiment). ) And the average value of the signal value in the region of interest R in the analysis result of the moving image of the reference imaging apparatus 1a (this is referred to as the signal average value) or the change amount of the signal average value. Using the relationship, the moving amount of the structure S included in the moving image of the imaging device 1 (in this embodiment, the imaging devices 1b and 1c) different from the reference imaging device 1a and the different imaging devices 1b and 1c. A signal average value in the region of interest R in the analysis result of the moving image or an estimated value obtained by estimating a change amount of the signal average value is obtained.
Then, a correction formula is obtained from the difference between this estimated value and the signal average value in the region of interest R or the amount of change in the signal average value in the actual analysis result of the moving images of the different imaging devices 1b and 1c, and the correction formula Is applied to correct the analysis results of the moving images of the different photographing apparatuses 1b and 1c.

FIG. 4 shows a case where a moving image is obtained by photographing the chest of the subject M under the same photographing conditions with a photographing device 1a as a reference and a photographing device 1 (for example, photographing devices 1b and 1c) different from the reference photographing device 1a. 4 shows a time-series change in the moving amount of the structure S included in each frame constituting each moving image and the average value (signal average value) of signal values in each frame in each moving image.
In FIG. 4, the graph which shows the time-sequential change of the moving amount | distance of the structure S contained in a moving image is shown in the middle stage. In the middle graph, the horizontal axis is time t, and the vertical axis is the position of the structure S (diaphragm in this embodiment). In this graph, the position of the structure S included in the moving image captured by the image capturing device 1a is indicated by a solid line, and the structure S included in the moving image captured by the image capturing devices 1b and 1c different from the image capturing device 1a. The position is indicated by a broken line.

In FIG. 4, on the lower side of the middle graph, a certain pixel (circle in FIG. 4) in the region of interest R of each frame in the moving image (reference moving image D) captured by the reference image capturing apparatus 1a. The density average values (Ave.) of the small squares in FIG. 4 are schematically arranged in time series (Da to De in FIG. 4), and further, the difference in density average value between frames in each moving image is provided below the density average values (Ave.). The time series change of the signal value is shown. FIG. 4 shows an example in which the difference signal value of the concentration average value between adjacent frames is obtained and the time series change is observed as the dynamic analysis process. It is not limited to the difference process between them, and other analysis processes may be adopted.
At the bottom of FIG. 4, the time series change of the differential signal value is shown by a solid line graph. In this graph, the horizontal axis represents time t, and the vertical axis represents the difference signal value (Ave.) of the density average value of the region of interest R between frames.

  As shown in FIG. 4, the difference signal value (Ave.) of the average density value in the region of interest R of each frame of the moving image photographed by the reference photographing apparatus 1a and the reference photographing apparatus 1a. If the displacement amount of the structure S (here, the diaphragm) is large between the movement amount of the structure S (here, the diaphragm) included in the moving image, the difference signal value of the concentration average value in the region of interest R is Correlation with increasing size is observed.

In addition, in the upper side of the middle graph in FIG. 4, in the region of interest R of each frame in the moving image d photographed by the photographing device 1 (for example, the photographing devices 1 b and 1 c) different from the reference photographing device 1 a. Density average values (Ave.) of pixels with a certain pixel (see the small square in the circle in FIG. 4) are arranged in a time series (da to de in FIG. 4), and further above each moving image The time-series change of the difference signal value of the density | concentration average value between frames is shown. Here, as an example of the dynamic analysis process, an example is shown in which the difference between the signal values between adjacent frames is obtained and the time series change is observed. However, as the dynamic analysis process, the difference between adjacent frames is shown. It is not limited to processing, and other analysis processing may be adopted.
In the uppermost part of FIG. 4, the time series change of the difference signal value is shown by a solid line graph. In this graph, the horizontal axis represents time t, and the vertical axis represents the difference signal value (Ave.) of the density average value of the region of interest R between frames.

When correcting the analysis result of the moving image, the control unit 31 serving as a correcting unit detects the position and amount of the structure S (for example, the diaphragm) included in the moving image captured by the reference image capturing apparatus 1a, and the moving image. An imaging device 1 (for example, an imaging device) different from the reference imaging device 1a using a correlation with a signal average value in the region of interest R (for example, lung field) obtained by analyzing 1b, 1c) The signal average value or signal in the region of interest R (for example, lung field) that should be obtained by analyzing the moving image from the moving amount of the structure S (for example, the diaphragm) included in the moving image captured by 1b, 1c) Find the expected value of the average change. At the top on the right side of FIG. 4, an expected signal curve representing a time-series change in the predicted value is indicated by a broken line.
Further, the control unit 31 calculates the signal average value or the signal average in the region of interest R in the actual analysis result of the moving image captured by the imaging device 1 (for example, the imaging devices 1b and 1c) different from the reference imaging device 1a. An actual value of the amount of change in value (indicated by a solid line in the uppermost graph on the right side of FIG. 4) is acquired, a difference between this actual value and the expected value is obtained, and a correction formula is derived from this difference.
And the control part 31 becomes a reference | standard by applying this correction formula to the analysis result of the moving image d image | photographed with the imaging | photography apparatuses 1 (for example, imaging | photography apparatus 1b, 1c) different from the imaging | photography apparatus 1a used as a reference | standard. Correction is performed so as to be equivalent to the analysis result of the moving image D photographed by the photographing apparatus 1a.

  As described above, the analysis result of the moving image d obtained from the photographing apparatus 1 (for example, the photographing apparatuses 1b and 1c) is equivalent to the analysis result of the moving image (reference moving image D) photographed by the reference photographing apparatus 1a. By correcting the analysis result of the moving image as described above, the analysis result of the moving image (reference moving image D) captured by the reference image capturing device 1a and the image capturing device 1b, Even when the analysis result of the moving image d obtained from 1c is mixed, dynamic analysis can be performed by appropriately comparing these. This makes it possible to obtain an appropriate analysis result that contributes to diagnosis.

《Correction according to subject's physique information》
As described above, a moving image (reference moving image D) photographed by the reference photographing device 1a and a moving image obtained from a photographing device 1 (for example, photographing devices 1b and 1c) different from the reference photographing device 1a. When performing correction to match the characteristics with d so as to be the same, the control unit 31 that is correction means moves the structure S based on information on the physique of the subject M (this is physique information). And the correlation coefficient in the correlation between the moving image or the signal value included in the analysis result of the moving image may be corrected.

The correlation between the moving amount of the structure S and the signal value included in the moving image or the analysis result of the moving image may differ depending on the physique of the subject M. For this reason, it can be expected that finer and more accurate correction processing is performed by correcting the correlation coefficient in consideration of the physique.
Such correction based on the physique information is applied as necessary in both cases where the correction is performed on the moving image itself and in the case where the correction is performed on the analysis result of the moving image. It is possible.
Here, the physique of the subject M is related to body size such as height, weight, and body thickness, whether it is muscular, related to body composition such as skeleton, bone density, body fat percentage, etc. The concept includes a wide range of physical features that affect the degree of transmission.
The physique information of the subject M can be extracted from, for example, patient information included in order information when photographing.
In the following description, a case where correction is performed according to whether the body weight is heavy or not will be described as an example of the physique.

FIG. 5 shows a case where the moving image itself is corrected, taking time t on the horizontal axis and taking the average density value (Ave.) of the region of interest R between frames on the vertical axis.
In FIG. 5, the time-series change of the density average value of each pixel is shown by a solid line graph, and the density average obtained using the correlation between the moving amount of the structure S and the density value (density average value) of the moving image. A prediction curve representing a time-series change of an expected value of the value or the amount of change in density is shown by a broken line.
Further, the correlation coefficient in the correlation is corrected based on the physique information of the subject M, and the correlation coefficient in the correlation between the moving amount of the structure S and the signal value included in the moving image or the analysis result of the moving image is corrected. The physique-corrected predicted curve representing the chronological change of the average concentration value and the predicted value of the amount of change in the density (predicted value after physique correction) is shown by a dashed line.
The correction of the correlation coefficient based on the physique information may be performed by a one-step determination as to whether or not the correction is performed, for example, if the correction is performed if the threshold is equal to or greater than a certain threshold. There are correction values associated with threshold values in multiple stages, such as no correction, correction with the first correction value if 50 kg or more and less than 80 kg, and correction using the second correction value if 80 kg or more. The correction value to be applied may be changed according to the physique information of the subject M.

When the control unit 31 serving as a correction unit appropriately corrects the correlation coefficient based on the physique information and obtains the predicted value after the physique correction using the corrected correlation coefficient, the photographic image differs from the reference imaging apparatus 1a. Acquire actual density average values and measured values of change in density (indicated by a solid line in FIG. 5) in a region of interest R (for example, lung field) in a moving image captured by the apparatus 1 (for example, the imaging apparatuses 1b and 1c). Then, the difference between the actually measured value and the predicted value after physique correction is obtained, and a correction formula is derived from this difference.
Then, the control unit 31 applies the correction formula to all the pixel data of the moving image d photographed by the photographing apparatus 1 (for example, the photographing apparatuses 1b and 1c) different from the reference photographing apparatus 1a. Correction is performed so that the characteristics of the image are the same as those of the moving image D photographed by the photographing apparatus 1a.

  In this way, taking into consideration the physique of the subject M, a moving image (reference moving image) captured by the reference photographing device 1a with respect to the moving image d obtained from the photographing device 1 (for example, the photographing devices 1b and 1c). By correcting the moving image so as to be equivalent to the input / output characteristics of D), the moving image (reference moving image D) photographed by the photographing device 1a serving as a reference is taken as a target for dynamic analysis in the analyzing device 3. Even when the moving images d obtained from the devices 1b and 1c are mixed, or even when moving images of different subjects M are mixed in the same shooting device, they are differently captured across these different shooting devices. Even when moving images of the subject M are mixed, it is possible to perform an appropriate comparison that contributes to diagnosis between these moving images and the analysis results thereof.

[effect]
As described above, according to the analysis device 3 and the analysis system 100 according to the present embodiment, when receiving a moving image from a plurality of different imaging devices 1 and displaying the received moving image and the analysis result of the moving image, The control unit 31 serving as a correction unit corrects the moving image or the analysis result of the moving image using the moving amount of the structure S included in the moving image.

  For this reason, when the manufacturers of the plurality of imaging devices 1a, 1b, and 1c are different, or even when the manufacturers are the same, there are individual differences in the imaging devices 1a, 1b, and 1c due to settings, etc. In the case where a plurality of types of apparatuses such as a radiographic image capturing apparatus, CT, and MRI are mixed as the image capturing apparatuses 1a, 1b, and 1c, the characteristics of moving images obtained by a plurality of different image capturing apparatuses 1 are different (variation varies). Even in such a case, the moving images obtained by the respective photographing devices 1a, 1b, and 1c can be obtained by appropriately correcting the moving images obtained by these photographing devices 1a, 1b, and 1c and the analysis results of the moving images. It becomes possible to accurately compare the analysis results of the images.

In the present embodiment, paying attention to the correlation between the amount of movement of the structure S existing in the human body and the signal value included in the moving image or the analysis result of the moving image, the control unit 31 serving as the correcting means determines this correlation. Used to correct moving images and moving image analysis results.
For this reason, it can be set as the state which can compare the analysis result of a moving image accurately exactly easily and appropriately.

In the present embodiment, the correlation is obtained from the relationship between the movement amount of the structure S in the moving image and the density average value or the change amount of the density average value in the region of interest R in the moving image, and the correction target is the original. Correction can be made in the case of a moving image itself.
In this way, by correcting the moving image before any image processing or the like is performed, it is possible to obtain a state in which the analysis results of the moving image can be more appropriately compared.

Further, in the present embodiment, the correlation is obtained by the relationship between the movement amount of the structure S in the moving image and the signal average value in the region of interest R in the analysis result of the moving image or the change amount of the signal average value. Even when the correction target is a moving image analysis result, the correction can be made.
For this reason, in the photographing apparatus 1 or the like, it is possible to appropriately compare the analysis results of moving images with each other even after some image processing or the like has already been applied.

Further, in the present embodiment, when correcting the moving image or the analysis result of the moving image, the control unit 31 that is a correcting unit corrects the correlation coefficient in the correlation based on the physique information about the physique of the subject of the moving image. You can also do it.
For this reason, taking into account the physique of the subject M, a moving image (reference moving image D) taken by the reference photographing device 1a with respect to the moving image d obtained from the photographing device 1 (for example, the photographing devices 1b and 1c). By correcting the moving image and the analysis result of the moving image so as to be equivalent to the input / output characteristics of (), it is possible to more appropriately compare the analysis results of the moving image.

[Modification]
Needless to say, the present invention is not limited to the above-described embodiment, and can be appropriately changed without departing from the gist of the present invention.

For example, in the present embodiment, it is assumed that the photographing device 1a of the photographing devices 1 in the analysis system 100 is a reference photographing device that captures the reference moving image D, but the reference moving image D is captured. The reference imaging device is not necessarily a substantial device that exists in the analysis system 100.
For example, the “reference imaging device” is a standard device whose input / output characteristics and the like have been previously grasped through experiments and the like, and the amount of movement of the structure in the moving image (reference moving image D) captured by this Correlation with changes in concentration in the region of interest and changes in the signal value of the kinetic analysis result is pre-existing in the analysis device (in the storage unit 32 of the analysis device 3, etc.) at the time of factory shipment in the form of factory shipment values (data). You may do it.
In this case, all of the imaging devices 1 existing in the analysis system 100 are “imaging devices different from the reference imaging device”, and the moving image d acquired by each of these imaging devices 1 is included in the analysis device 3. The control unit 31 of the analysis device 3 is equal to the correlation between the movement amount of the structure in the reference moving image D stored in advance and the change in the concentration in the region of interest and the change in the signal value of the dynamic analysis result. In other words, correction processing is performed in the correction means.

In the present embodiment, a moving image shot by a “photographing device different from the reference image-taking device” and an analysis result of this moving image are combined with a moving image shot by the “reference image-taking device”. Although an example of correction has been mainly described, the correction process performed by the analysis device 3 (in this embodiment, the control unit 31 of the analysis device 3 functioning as a correction unit) is not limited to this.
For example, the control unit 31 of the analysis device 3 as a correction unit uses the moving image (that is, the reference moving image D) captured by the reference imaging device (that is, the imaging device 1a) and the analysis result as the reference imaging. It becomes a reference so that it can be compared with a moving image (that is, moving image d) photographed by a photographing device (that is, photographing devices 1b and 1c) different from the device (that is, photographing device 1a) and its analysis result. You may make it correct | amend with respect to the reference | standard moving image D image | photographed with the imaging device 1a, or its analysis result. Alternatively, both the reference moving image D and the moving image d may be corrected so that the reference moving image D and the analysis result thereof, and the moving image d and the analysis result thereof are brought close to an intermediate point between them.

Further, the correlation between the movement amount of the structure S of the moving image (reference moving image D) obtained by the “reference photographing device” and the signal value is not limited to the case where the moving object is applied to the same subject M.
For example, a sample of a plurality of subjects M is collected to create a model of the correlation between the amount of movement of the structure S and the signal value, and this can be applied in common when shooting various subjects M. Good. A more universal model can be realized by creating a correlation model based on many samples.

In the present embodiment, the region of interest R is a lung field and the structure S is a diaphragm. However, the region of interest R and the structure S include the position / movement amount of the structure S and the region of interest R. As long as there is a correlation with the change in the signal value, the lung field and the diaphragm are not limited.
For example, when the blood flow analysis in which the region of interest R is blood flow around the heart is performed, the outer edge of the heart having a correlation with the blood flow around the heart becomes the structure S, and the control unit 31 The moving image or the analysis result of the moving image is corrected using the correlation between the position / movement amount of the outer edge and the blood flow around the heart.

DESCRIPTION OF SYMBOLS 1 Imaging device 1a Reference imaging devices 1b and 1c Imaging device 3 different from reference imaging device 3 Analysis device 31 Control unit 100 Analysis system D Reference moving image d Moving image

Claims (6)

An analysis device that receives moving images from a plurality of different photographing devices and displays the received moving images and analysis results of the moving images,
An analysis apparatus comprising correction means for correcting the moving image or the analysis result of the moving image using a moving amount of a structure included in the moving image.   The correction unit corrects the moving image or the analysis result of the moving image by using a correlation between the moving amount of the structure and a signal value included in the moving image or the analysis result of the moving image. The analysis apparatus according to claim 1.   The correction means corrects a correlation coefficient in the correlation based on information about a physique of a subject of the moving image when correcting the moving image or an analysis result of the moving image. 2. The analysis apparatus according to 2. The signal value is a density average value in the region of interest in the moving image or a change amount of the density average value,
The correction means includes a movement amount of the structure included in a moving image of the reference photographing apparatus and a density average value or a change amount of the density average value in the region of interest in the moving image of the reference photographing apparatus. Using the correlation, the moving amount of the structure included in the moving image of the photographing device different from the reference photographing device, and the density average value or the density average value in the region of interest in the moving image of the different photographing device An estimated value obtained by estimating the amount of change is obtained, and a correction formula is obtained from the difference between this estimated value and the density average value in the region of interest actually obtained from the moving image of the different imaging device or the amount of change in the density average value. 4. The analysis apparatus according to claim 2, wherein the correction formula is applied to correct all pixel data of moving images of the different photographing apparatuses. The signal value is a signal average value in the region of interest in the analysis result of the moving image or a change amount of the signal average value,
The correction means includes a movement amount of the structure included in the moving image of the reference photographing apparatus and a change in the signal average value or the signal average value in the region of interest in the analysis result of the moving image of the reference photographing apparatus. The amount of movement of the structure included in the moving image of the imaging device different from the reference imaging device and the signal in the region of interest in the analysis result of the moving image of the different imaging device using the correlation with the amount An estimated value obtained by estimating an average value or a change amount of the signal average value is obtained, and the estimated value and a signal average value or a change amount of the signal average value in the region of interest in the actual analysis result of the moving image of the different imaging device. The analysis apparatus according to claim 2 or 3, wherein a correction formula is obtained from the difference, and the analysis result of the moving image of the different photographing apparatus is corrected by applying the correction formula. A standard imaging device capable of capturing moving images;
A shooting device capable of shooting a moving image and different from the reference shooting device;
The analysis device according to any one of claims 1 to 5,
An analysis system comprising:

Images