JP2018536841A - Test system and test method - Google Patents

Abstract

A system for testing the proper functionality of an atomizer for dispensing fluids in the form of an aerosol is proposed, the system includes an atomizer and a test device, the atomizer inserting a container holding the fluid and the container And / or a housing part for exchanging it, the container is movable relative to the housing part for dispensing fluid, and the test device moves the container as fluid is dispensed Including a measuring device for measuring. In addition to this, a method for testing the proper functionality of an atomizer for dispensing fluid in the form of an aerosol is proposed, the atomizer inserting and / or replacing the container holding the fluid. And the container is moved relative to the housing part to dispense fluid, and the movement of the container is measured and / or analyzed when the fluid is dispensed.
[Selection] Figure 3

Description

  The present invention relates to a system or test system for testing the proper functionality of an atomizer for dispensing a fluid in the form of an aerosol as defined in the preamble of claim 1, the form of aerosol as defined in the preamble of claim 10. 17. A method or a test method for testing proper functionality of an atomizer for dispensing a fluid with a test apparatus, and a test apparatus according to claim 16.

  The term “atomizer” should preferably be taken to mean a structured device specifically designed to atomize a fluid, in particular a pharmaceutical formulation, or to turn the fluid into an aerosol. Particularly preferably, the atomizer in the sense of the present invention is an inhaler for inhaling fluid in the form of an aerosol. Preferably, an atomizer in the sense of the present invention comprises a container as a reservoir for the atomized fluid. The container is preferably insertable into the atomizer (eg, by opening a cover, etc.) and is arranged or exchanged in an accessible manner there. In this context, an atomizer is considered in particular an atomizer in which the container is preferably axially movable relative to the housing or housing part for dispensing fluid. WO 09/047173 A2 discloses an example of such an atomizer.

  When a fluid, especially a liquid pharmaceutical formulation, is atomized by an atomizer of the type mentioned at the outset, the preciseest possible amount of active ingredient should be converted into an inhaled aerosol. Aerosols generated in this manner should be distinguished by having a low average droplet size with a narrow droplet size distribution and low impact or low dispersion rate. Preferably, the droplets produced in this manner have a droplet diameter of less than 5 μm, in particular between 2 μm and 5 μm, since this size droplet is suitable for the lung system when inhaled It is because it is deposited.

  In the sense of the present invention, the term “fluid” must be understood and interpreted broadly. In particular, the term “fluid” covers liquid solutions as well as dispersions or suspensions and the like.

  In the present invention, the term “aerosol” should be taken to mean a cloud-like or mist-like accumulation of a large number of droplets of fluid, preferably already atomized by an atomizer, where the droplets are preferably Have a low speed and / or at least a substantially random direction of movement. An “aerosol” can for example have or form a cloud of conical droplets, the principal dispersion direction of the droplet cloud being in particular at least substantially coincident with the main emission direction or the emission pulse direction.

  When manufacturing or producing atomizers of the type mentioned at the beginning, for example as part of quality control, eg in full or 100% inspection and / or as part of sample inspection, atomizers are checked for defects or they are appropriate It is necessary to check that it is functioning properly and / or to discard a defective or prone atomizer.

  The term “proper functionality” preferably means the function of the atomizer that is necessary for the fluid to be dispensed or atomized by the atomizer or to fulfill the intended purpose or function. Then you should catch. Preferably, the proper functionality of the atomizer corresponds to the extent that the requirements for the atomizer or for the (target) function of the atomizer can be met.

  Preferably, proper functionality is checked using measurements detected during atomizer activation. Particularly preferably, a target value and / or a limit value in a range considered to correspond to the measurement value of the functional atomizer is set as a part of quality control, for example.

  Primarily, a functional atomizer to produce an inhalable aerosol should dispense a specified amount of fluid or pharmaceutical formulation in the form of an aerosol cloud or spray mist with specified characteristics. This basic function of the atomizer uses measurements taken on the generated aerosol cloud or spray mist, for example, direct measurements of the droplet size distribution (eg optical methods or cascade impactors). According to the measured value of the total weight of the fluid dispensed into the spray mist.

  In some atomizers, for example, in nasal spray pumps, spray fog characteristics such as spray pattern, spray cloud shape, or droplet size distribution may depend on how the atomizer or pump is triggered. . In conventional nasal spray pumps, the upper part, including the outlet opening, is pushed towards the drug container against the restoring force to trigger the pump. In this case, the slow activation is likely to in some cases result in a sparse cloud formation and spill fluid, and rapid activation may cause many of the droplets to be absorbed by the nasal mucosa. Instead, it is thought that there is a possibility of generating a spray mist that is fine enough to be inhaled into the deeper airways. In order to check the proper functionality of such nasal spray pumps according to certain criteria without individual intervention as required as part of clinical approval, WO 2004/091806 A1 Proposes the use of a device that can trigger this type of nasal spray pump or “metered dose inhaler” (MDI) in a mechanically controlled manner. This activation adjustment feature allows the device to scrutinize the relationship between the mechanical interaction of the moving and stationary atomizer parts and the atomizer function in combination with measurements taken with the atomizer. For this purpose, for example, the analysis of spray patterns on thin-layer chromatography plates (TLC) is described as a measurement method. In this way, it is possible to generate data that can be used to define parameters for an automatic triggering system that reduces variability in normal inspections (as compared to triggering steps performed manually by the tester). It is.

  DE 10136554 A1 discloses an experimental method for determining the particle size distribution in an aerosol from an inhaler and a device for carrying out this method. This document proposes measuring the particle size of aerosol particles by laser diffraction analysis or laser diffraction methods. In this case, practical conditions are established when using the inhaler as intended by the patient, i.e. in particular measurement conditions that reproduce high air humidity levels in the human oropharyngeal site. EP 2 382 237 A1 is built on the method described above and discloses an experimental measurement method in which the determination of the inhalable part (fine particle part) of the aerosol is combined with the measurement of the duration of the spray. During particle measurement in this case, the scattered laser light is focused towards the semiconductor detector by a converging lens and analyzed by an analytical method based on Mie scattering theory or Fraunhofer method.

  Other possible examples of measurement variables are the flow rate in the atomizer nozzle duct, the dispense volume and / or dispense weight of the fluid, in particular per trigger and / or per unit time, the volume of fluid in the leaking atomizer and And / or weight and / or fluid pressure and / or fluid pressure drop in the atomizer. In some cases, measuring such measurement variables directly is complex and thus has a limited range, especially in batch production processes such as automated inspection and / or 100% inspection or 100% screening inspection. This is only possible.

WO 09/047173 A2 WO 2004/091806 A1 DE 10136554 A1 EP 2381237 A1 WO 96/06011 A2

  Against this background, the object of the present invention can be preferably identified, defined, evaluated and / or indexed in a simple, cost-effective, quick and / or reliable manner. Or providing a test system and test method for testing the proper functionality of an atomizer to be identified, defined, evaluated and / or indexed and any atomizer fault failures.

  In particular, test methods and test systems should be suitable for use in batch production processes.

  The above object is achieved by a test system according to claim 1, a test method according to claim 10, and a test apparatus according to claim 16. The dependent claims relate to advantageous developments.

  The test device according to the invention or the system according to the invention for testing the proper functionality of an atomizer preferably comprises an atomizer and a test device for testing the atomizer.

  In one aspect of the invention, as part of the functional test, the proper functionality of the atomizer is moved relative to the atomizer itself, preferably against one or more moving parts of the atomizer (especially during activation). To be tested at least in part using the measurements taken). In this regard, the measured values are preferably detected against measured variables that are correlated with the characteristics of the spray mist, especially due to the corresponding operating principle of the atomizer. As a result, it is possible to provide an apparatus or test system for testing the proper functionality of an atomizer whose measurement time is at most slightly longer than the time required to activate the atomizer. Preferably, this functional test is performed in a particularly automated 100% test or 100% screening test.

  According to the present invention, with respect to an atomizer in which the container holding the fluid to be dispensed moves while the fluid is being dispensed, the movement of the container is measured and the measured value detected by the associated measuring device is: It is compared with the target value and / or limit value within the data processing device (eg in a computerized manner). When the measured value does not comply with the target value (specially specified with the deviation range) and / or the measured value is outside the range defined by the limit value, the atomizer is considered defective in or by the test system Identified and preferably discarded automatically. If the electronics of this type of automation system are properly designed, the atomizer cycle time is substantially determined by the duration of the actual measurement that ends when all fluid / spray is dispensed according to the present invention. Is done. The test method is therefore well suited for use in batch production and is also particularly suitable for use in 100% inspection.

  According to another aspect of the present invention, in the test system, this type of measurement for the atomizer itself is combined with the measurement for the aerosol cloud produced thereby or the spray fog produced thereby.

  For this purpose, the test system preferably includes a spray parameter measurement device and / or an imaging recording device connected to the data processing device of the system. In the spray parameter measuring device, the predefined spray parameters are measured based on the spray photograph and the measured values are compared with predefined limit values by the data processing device. Alternatively or additionally, the image from the imaging and recording device is compared with the reference image in the data processing device.

  The atomizer is preferably automatically identified as defective when the measured value or image detected for that purpose does not conform to the target value or reference image and / or is outside the range defined by the limit value or reference image (And in particular discarded).

  Particularly preferably, a light section or light curtain is generated in the spray parameter measuring device for generating a spray photograph.

  Preferably, in addition to the step of assembling the atomizer, the atomizer production is also preferably an automated screening test process in which selected measurement variables reflecting the general function of the atomizer are measured, as well as the atomizer selected Including a sampling stage where the sample undergoes a detailed laboratory examination. In this type of laboratory inspection, the selected atomizer is preferably tested to the point of failure while reproducing the user usage pattern. In that process, laboratory tests also make more complex measurements (compared to screening tests), for example known from DE 10136554 A1, in particular the measurement of the droplet size distribution and / or the measurement of the discharged fluid weight. Accompany.

  The atomizer preferably has the option to insert and / or replace a container holding the fluid (this option is for example by means of an access opening in the atomizer housing and / or by a removable or openable housing part) Can be provided). Preferably, the user is particularly insertable, particularly preferably replaceable and uses an atomizer with a container holding fluid, the container being a housing part for dispensing or atomizing the fluid or forming an aerosol Is movable.

  In laboratory tests where the user usage pattern is reproduced, a container filled with a fluid that the user wants to atomize is preferably used. For inhaler testing, the container is therefore preferably a cartridge filled with a liquid pharmaceutical formulation or a suitable placebo.

  However, in a 100% test or 100% screening test, the atomizer is preferably inserted to contain a liquid or test fluid that can be removed from the atomizer, particularly without leaving any residue (to prevent contamination or accumulation). Tested using a new container. The corresponding liquid, such as water, or particularly preferably ethanol, needs to be very pure. For 100% testing or 100% screening testing, the atomizer preferably includes a container that can interact with the test equipment used. For this purpose, for example, in the case of optical measurements, the container may have an appropriate reflective surface (or in the case of electrical or inductive measurements appropriate electrical or magnetic properties, or tactile or mechanical measurements. Especially if appropriate contours etc.). Optionally, the container includes a readable label.

  Preferably, the atomizer is based on an active atomization principle, in particular the energy required for atomization is released from the energy storage mechanism and / or in particular the atomization is a trigger button or switch on the atomizer, etc. Happens automatically after is started.

  In order to generate pressure for the atomization of the fluid, the atomizer particularly preferably comprises a mechanical pump mechanism, in particular a piston pump mechanism, and the container is preferably moved with the moving parts of the pump mechanism. Preferably, the pump mechanism is combined with a spring that acts as an energy storage mechanism.

  In another aspect of the invention, which can also be performed independently for 100% inspection or 100% screening test, the system or test apparatus preferably atomizes the fluid to test the proper functionality of the atomizer. Measuring the movement of the container of the atomizer or the movement of the bottom of the container, preferably optically, mechanically and / or electrically and / or non-contacted when or during dispensing Or a measuring device for detection.

  Particularly preferably, the measuring device determines the velocity of the container or container bottom, the (axial) stroke of the container or container bottom, and / or the duration of the stroke, preferably optically, mechanically and / or electrically. And / or designed to measure in a non-contact manner. A test system that is particularly simple, quick and easy to automate and / or can be integrated into the production process is thus provided. In this case, the term “stroke” is taken to mean a path or passage over a path between two end positions between which the container and the container bottom move, in particular between the situation before and after the atomizer is triggered. Should.

  The term “movement” preferably means the speed of the container or container bottom, the stroke of the container or container bottom, and / or the duration of the stroke of the container or container bottom, when or during the fluid being dispensed or atomized. Should be taken to mean. In particular, movement of the container or container bottom covers the position of the container or container bottom as a function of the duration of fluid dispensing or atomization, and / or movement depends on the position of the container or container bottom as a function of time. It can be measured, defined and / or quantified. Most preferably, the test system or measuring device measures or quantifies the movement, in particular the velocity of the container or the bottom of the container, the stroke, and / or the duration of the stroke, by means of a corresponding measurement, particularly when the fluid is dispensed. Designed as such.

  Preferably, the predefined target value for container movement can be set for a functional or at least substantially faultless atomizer. In this regard, the measurement variable is preferably the container speed, the container stroke (ie the path of movement of the container), and / or the duration of the container movement corresponding to the container stroke. Preferably, these measured variables or the interaction of these variables are in particular the flow rate in the atomizer nozzle duct per trigger and / or unit time, the dispense volume and / or dispense weight of the aerosol, the leaking atomizer It can be correlated with characteristics such as fluid volume and / or weight and / or fluid pressure and / or fluid pressure drop in the atomizer.

  For functional or at least substantially fault-free atomizer measurement variables, target ranges and / or limit values are preferably specified, and the target values, target ranges and / or limit values are preferably conceptually Has been determined empirically, numerically, practically and / or theoretically.

  The present invention particularly preferably relates to testing an atomizer using a mechanical or manually activatable pump or a mechanical or manually activatable tension mechanism to pressurize a fluid or form an aerosol. . In this case, the movement of the container may correspond to the piston movement of the pump, pressure generator, or valve in the atomizer, and / or the movement speed of the container may correspond to the fluid dispensing speed. In principle, however, other mechanisms are possible, particularly those in which the dispensing volume, dispensing speed and / or properties of the aerosol correspond to the characteristics of the container movement. It has been found to be particularly advantageous to check for proper functionality or compliance with target values or tolerances by using also container movements at least while the fluid is being dispensed.

  The proposed method or test method for testing the proper functionality of an atomizer for dispensing fluid in the form of an aerosol is also preferred for movement of the atomizer container when the fluid is dispensed or atomized. Is distinguished in that it is measured by a measuring device and / or preferably analyzed by a data processing device.

  Particularly preferably, the speed of the container or container bottom, the stroke of the container or container bottom, and / or the duration of the container stroke when the fluid is dispensed or metered is measured and / or analyzed and / or Compared with target values, in particular target speed, target stroke, or target duration, and / or limit values, in particular maximum and / or minimum speed, maximum and / or minimum stroke, and / or maximum or minimum duration. The In this way, corresponding advantages are obtained.

  Particularly preferably, the measuring device measures the movement of the container by optical triangulation. In this case, a visible modulated light spot is preferably projected onto the surface of the bottom of the container, and an image of at least a part of the reflection of this light spot is a spatial resolution element (eg CCD element) or sensor (receiver). Generated in a position-sensitive manner by a receiver optical system arranged at a specified angle on top (contained in the optical system). The container bottom distance is preferably calculated from the sensor output signal by a digital signal processor.

  In accordance with the present invention, the measurement device and associated data processing device is preferably an automated test apparatus in which an atomizer whose detected value is outside the predefined limit value is preferably automatically discarded as a bad atomizer. Is part of. The data processing device therefore analyzes the measurements detected by the measurement device and / or compares them with the target value and / or limit value and / or the measurement detected with respect to the atomizer in the test system Designed to identify as bad when the value does not conform to the target value and / or is outside the range defined by the limit value. As an atomizer identified as defective is discarded, the system according to the present invention provides a discharge in which the atomizer is preferably slid automatically and / or discarded after it is identified as defective. Includes devices.

  Another aspect of the present invention, which can be performed independently, relates to a test device for testing the proper functionality of the atomizer, which is designed to dispense fluids in the form of an aerosol and test The device includes a holding device for holding or gripping the atomizer, an activation device for activating the atomizer, a measurement device, and a data processing device, the measurement device moving when fluid is dispensed Designed to measure atomizer parts, the data processing device analyzes the measurements detected by the measurement device and / or compares them with target values and / or limit values and / or detected measurements The atomizer is considered bad if the value does not conform to the target value and / or is outside the range defined by the limit value. It is designed to identify.

  According to another aspect of the invention, which can be performed independently, the test device is used to test the proper functionality of the atomizer, the atomizer being designed to dispense fluid in the form of an aerosol, And a container that is preferably insertable and particularly preferably replaceable for holding fluid, and a housing part, the container being moved relative to the housing part for dispensing fluid, Movement is measured when fluid is dispensed. In this way, corresponding advantages are generated.

  Further aspects, features, characteristics and advantages of the present invention will become apparent from the following description of the preferred embodiments given on the basis of the claims and drawings.

It is a schematic sectional drawing through the atomizer in a non-tension state. It is a schematic sectional drawing through the atomizer in the tension state rotated 90 degrees compared with FIG. FIG. 2 is a schematic diagram of the proposed test system having the atomizer according to FIG. 1 and the proposed test apparatus. FIG. 5 shows a schematic curve of the container stroke as a function of time.

  In purely schematic drawings that are not necessarily to scale, the same reference numerals are used for similar or similar components, and the same or similar features and advantages are where the description is not repeated. Can also be obtained.

  1 and 2 show an atomizer 1 for atomizing a fluid 2, especially a high potency pharmaceutical, etc., the proper functionality of which can be tested, for example, with a test system or test method according to the present invention. 1 and 2 show the atomizer 1 in two states that occur when used by a user. 1 and 2 are schematic views of the atomizer 1 in a non-tension state (FIG. 1) and a tension state (FIG. 2). In this case, the terms “non-tension” and “tension” represent the state of the energy storage mechanism housed in the atomizer and preferably formed by the main spring 7. In the “tensioned state” (FIG. 2), the energy storage mechanism is loaded to a certain degree and the atomizer 1 is ready to be triggered. The “non-tensioned state” (FIG. 1) shows the atomizer 1 in a triggered state (not ready for triggering).

  In particular, the atomizer has an option to trigger, in particular the trigger button 8a, and upon activation, a spray mist starts to be generated automatically or independently or the aerosol 14 starts to be automatically or independently dispensed. Thus, advantageously, the spray mist is not exposed to any effects from the handling of the atomizer by the user / patient or only exposed to negligible effects. In this embodiment, the atomizer 1 changes from a “tensioned” state to a “non-tensioned” state (while fluid is dispensed or a spray mist is generated) upon triggering or by pressure from the trigger button 8a.

  In particular, the atomizer 1 is formed as a portable inhaler and preferably operates without high pressure gas.

  When a fluid 2, preferably a liquid, in particular a pharmaceutical product, is atomized by the atomizer 1, preferably an aerosol is formed and the user or patient (not shown) inhales the atomized fluid 2 or aerosol 14, in particular. The outside air can preferably be sucked into the mouthpiece 13 through at least one outside air opening 15. Typically, the medicament is inhaled at least once a day, in particular several times a day, preferably at defined intervals, particularly preferably depending on the patient's illness.

  The atomizer 1 includes a container 3 that holds a fluid 2 that is preferably insertable and preferably replaceable. The container 3 preferably forms a reservoir for the fluid 2 to be atomised.

  Preferably, the container 3 (when used by the user or in the state shown in FIGS. 1 and 2), for example, to supply up to 200 weighing units, ie up to 200 atomizations or uses. Contains a sufficient amount of fluid 2 or active ingredient. A typical container 3 holds a volume of about 2 ml to 10 ml as disclosed in WO 96/06011 A2.

  The container 3 is preferably at least substantially cylindrical or cartridge-shaped and can be inserted into the atomizer 1 from below after opening the atomizer 1 and can be potentially exchangeable.

  Preferably, the container 3 has a flat surface on its bottom, or the container 3 includes a flat container bottom. Optionally, the container 3 includes a metal and / or reflective outer casing, and / or a metal and / or reflective container bottom, or a metal and / or reflective (outer) coating on the container bottom.

  Preferably, the fluid 2 is held in a fluid chamber 4 formed by a folding bag in the container 3.

  Preferably, the atomizer 1 also comprises a pressure generator 5 for conveying and atomizing the fluid 2 in each case in particular in a potentially adjustable metered amount.

  The pressure generator 5 preferably has an associated main spring 7 (with a mount 6 for the container 3 and a locking element 8 which can be actuated directly for unlocking purposes or preferably manually by means of a trigger button 8a. A supply tube 9 having a return valve 10, a pressure chamber 11, and a delivery nozzle 12 in the region of the mouthpiece 13. In order to trigger the atomizer, the locking element 8 is preferably slid transversely with respect to the main axis of the atomizer 1 / transversely with respect to the direction of movement of the movable part of the pressure generator 5, or a trigger button 8a. Is pushed transversely to the main axis / movement axis. Advantageously, the force applied to trigger therefore does not contribute to the force released upon triggering.

  The container 3 is preferably fixed in the atomizer 1 by means of a mount 6 and in particular latched so that the supply tube 9 enters the container 3. In this case, the mount 6 can be designed so that the container 3 can be removed and replaced.

  When the main spring 7 is pulled in the axial direction, the mount 6 moves downward in the drawing together with the container 3 and the supply tube 9, and the fluid 2 is sucked from the container 3 through the return valve 10 into the pressure chamber 11 of the pressure generator 5.

  Once the locking element 8 is activated and then the spring is relaxed, the supply tube 9 is returned upward again with its return valve 10 closed at this point as a result of the relaxation of the main spring 7 and now acts as a plunger. Therefore, the fluid 2 in the pressure chamber 11 is pressurized. This pressure expels fluid 2 through delivery nozzle 12, and fluid 2 is atomized onto aerosol 14 on delivery nozzle 12 as shown in FIG.

  Preferably, the supply tube 9 is held in place with respect to the container 3, in particular by the mount 6, when in its use position. Therefore, in particular, the (axial direction) movement of the supply tube 9 corresponds to the (axial direction) movement of the container 3.

  When the supply tube 9 or the return valve 10 acts as a plunger, the movement of the supply tube 9 or the container 3 corresponds to the displaced or deliverable amount of volume or fluid displaced in the pressure chamber 11.

  Considering in particular the hydrodynamic properties of the atomizer 1 or the properties of the delivery nozzle 12 (nozzle shape, mounted filter and / or hydrodynamic resistance formed by the delivery nozzle 12, etc.), the supply tube 9 or the return valve 10 and A conclusion can be drawn regarding the proper functionality of the atomizer 1 from the movement of another plunger and the corresponding movement of the container 3. In the atomizer 1 found in this embodiment, the fluid 2 in the pressure chamber 11 and / or upstream of the delivery nozzle 12 is pushed through the delivery nozzle 12 under pressure so as to produce an aerosol 14. It is discharged against the hydrodynamic resistance in the passage. In this step, the fluid pressure affects the resulting spray pattern or the properties of the aerosol 14. In this way, various malfunctions that could potentially require a plurality of different measurement methods for its detection of aerosol formation are measured in the movement of the atomizer 1 relative to the pump piston, in this case the supply. It can be detected by measuring the movement of the tube 9 or the container 3 attached to it (and moved with it by the supply tube 9). In this way, for example, by moving measurement, the direct detection of the leak required to measure the weight of the released aerosol, and the atomizer 1 spray duration and spray fog quality are adversely affected. A mispositioning or occlusion can be found (mispositioning increases the hydrodynamic resistance in the atomizer and fluid is drained more slowly from the pressure chamber). In the case of a leak, fluid is drained not only through the nozzle, but also through additional leak points, thereby reducing the overall hydraulic pressure in the flow path within the atomizer (thus, the fluid is more than from the hydraulic chamber). Expelled rapidly, ie faster piston movement and shorter spray duration are observed).

  For the atomizer 1 including the piston pump mechanism, the duration of the spray, i.e. the time that the aerosol is generated at the delivery nozzle 12, is preferably the piston (when the atomizer 1 is triggered or a spray mist is generated). It is determined by the time that the supply tube 9) or the container 3 connected to it moves. In this regard, the time required for the container 3 that moves with the piston when the atomizer 1 is triggered to move from the tensioned device position to the relaxed (non-tensioned) position is preferably measured by an optical measuring method. Is done. The duration of this container movement substantially correlates with or corresponds to the spray duration of the atomizer 1 as fluid is pushed out of the atomizer 1 through the delivery nozzle 12 during this movement.

  The atomizer 1 preferably has a housing part 16 and an inner part 17 (FIG. 2) which is rotatable relative to it and has an upper part 17a and a lower part 17b (FIG. 1), in particular a lower side which can be manually activated. The housing part or cover 18 is detachably fastened, in particular pressed against the inner part 17, preferably by means of a holding element 19.

  In order to insert and / or replace the container 3, the lower housing part 18 is preferably removable from the atomizer 1.

  The lower housing part 18 is rotatable towards the housing part 16 and the lower housing part is preferably accompanied by a lower part 17 b in the drawing of the inner part 17. As a result, the main spring 7 is pulled in the axial direction by a gear ring (not shown) acting on the mount 6. By this tension, the container 3 preferably moves downward in the axial direction until it takes the final position shown in FIG. In this state, the main spring 7 is pulled.

  Preferably, when a user or patient uses the atomizer and tension is applied for the first time, the spring 20 acting in the axial direction and arranged in the lower housing part abuts the container bottom 21 and is punctured by the piercing element 22 The seal on the container 3 or its bottom is punctured for the first time when it contacts the bottom, allowing air to flow in. During the atomization process, the container 3 is preferably returned to its initial position by the main spring 7.

The container 3 preferably undergoes a stroke movement during the tensioning process or while removing the fluid and / or while the fluid 2 is being atomized or dispensed. Particularly preferably, while the fluid 2 is being atomized or dispensed, the container 3 preferably moves by a stroke or stroke path Δs _stroke within the duration Δt _stroke at least partially at a linear velocity v _stroke. The duration Δt _stroke preferably corresponds at least substantially to the time during which the fluid 2 is dispensed or atomized.

  FIG. 3 is a schematic diagram of the proposed system 23 for testing the proper functionality of the atomizer 1.

  The proposed system or test system 23 preferably includes at least the components or modules of the atomizer 1 or the atomizer 1 and the proposed test apparatus 24.

  The atomizer 1 includes a container 3 that holds a fluid 2 that is preferably insertable and preferably replaceable. The container 3 preferably forms a reservoir for the fluid 2 to be atomized during the test.

  The container 3 is preferably at least substantially cylindrical or cartridge-shaped, can be inserted into the atomizer 1 and is replaceable or removable. In the example shown, a part of the container 3 is preferably directly accessible in the test system 23 for measurement.

  The container 3 is preferably at least substantially rigid. Particularly preferably, the container 3 is made of a plastic material, in particular a thermoplastic, most preferably a polyetheretherketone. Preferably, the container 3 has a flat surface on its bottom, or the container 3 has a flat container bottom.

  Optionally, the container 3 has a metal and / or reflective outer casing and / or a metal and / or reflective container bottom 21 or a metal and / or reflective (outer) coating on the container bottom 21. Including.

  The test device 24 is preferably designed to test the atomizer 1 and in particular to check that the atomizer 1 is functioning properly and / or for any defects.

  In particular, the system 23 or the test device 24 allows the atomizer 1 to function and / or satisfy and / or have a predefined function and / or the function of the atomizer 1 for that purpose. Alternatively, it is possible to test or confirm whether or not it corresponds to an individually defined specification.

  Particularly preferably, the system 23 or the test device 24 is designed to identify a defective atomizer 1 or a malfunctioning atomizer 1, preferably as part of the production or assembly of the atomizer 1. Most preferably, the defective atomizer 1 or the impaired atomizer 1 is identified and / or discarded afterwards by the system 23 or the test device 24.

  Preferably, the system 23 or the test device 24 is integrated or can be integrated into the production or production process for the atomizer 1, in particular the assembly process.

  The system 23 or the test apparatus 24 preferably has a holding device 25. The holding device 25 is arranged so that, in particular when the fluid 2 is dispensed, the atomizer 1 or at least the housing part 16 and / or the inner part 17 is immobile with respect to the holding device 25. It is preferably designed to hold, grip and / or receive the part 17.

  Preferably, the holding device 25 includes a hole 26 that can receive or receive at least a portion of the atomizer 1 or can be inserted or inserted.

  The system 23 or the test device 24 preferably comprises a measuring device 27 which is preferably designed to measure the movement of the piston or container 3 (feed tube 9) when the fluid 2 is dispensed.

  The measuring device 27 is preferably designed as an optical, mechanical and / or electrical measuring device.

In particular, the measuring device 27 determines the movement of the container 3 or the container bottom 21, in particular the speed v _stroke , stroke Δs _stroke , and / or stroke duration Δt _stroke in a non-contact, optical, mechanical and / or electrical manner. Designed to measure on.

In particular, the measuring device 27 is designed to measure the movement of the container 3 or the container bottom 21, in particular the velocity v _stroke , the stroke Δs _stroke and / or the stroke duration Δt _stroke in a triangulation method. In particular, the measuring device 27 houses or is formed by a laser triangulation sensor system.

  Preferably, the measuring device 27 comprises an emitter 28, in particular a laser or another source emitting radiation or electromagnetic waves, and optionally an A / D converter, and the radiation, image or other detected by the sensor 29. The detected signal is preferably converted into one or more electric signals by an A / D converter.

  The sensor 29 specifically detects the location or position and / or angle and / or intensity of incident radiation or electromagnetic waves and uses them as data or data, particularly as measured values or measured signals of the measuring device 27. It can be designed to convert to a signal.

  In particular, the sensor 29 is a CCD sensor or a CMOS sensor.

  Sensor 29 preferably includes a plurality of identifiable sensor portions known as pixels arranged adjacent to each other. It is preferred that the position or location of the incident electromagnetic wave or incident light can be determined in this way.

  The sensor 29 preferably corresponds to the emitter 28 so as to be able to accept, detect and / or convert electromagnetic waves or radiation output by the emitter 28.

  The sensor 29 is preferably an electromagnetic wave in order to change the location and / or angle and / or intensity of the incident electromagnetic wave, or to accurately determine them (especially to improve the analysis and / or accuracy in the sensor 29). An optical device such as a lens that focuses the light can be included.

  The emitter 28 and the sensor 29 are preferably arranged with respect to each other, and movement of the container 3 or the container bottom 21 may cause changes in the incident position, incident angle, and / or incident intensity of the electromagnetic wave or radiation output by the emitter 28. Designed to bring about. This has been found to be particularly advantageous for accurately determining the location or position, movement and / or speed of the container 3 or the container bottom 21.

  The emitter 28 is particularly designed to emit electromagnetic waves or radiation, in particular laser radiation, preferably towards the atomizer 1, especially towards the container 3, particularly preferably towards the container bottom 21. Preferably, the emitter houses or is formed by a laser diode.

  The measuring device 27 or emitter 28 is arranged below the atomizer 1, in particular below the container 3 or the container bottom 21, and / or so that the atomizer 1, in particular the container 3 or the container bottom 21 can be illuminated by the emitter 28. It is preferably oriented.

  In particular, the radiation emitted by the emitter 28 can be reflected by the container 3 or the container bottom 21, preferably at least partially towards the sensor 29. Optionally, the container 3 or the container bottom 21 includes a reflective coating (not shown) for reflecting radiation emitted by the emitter 28.

  Preferably, the emitter 28 is relative to the atomizer 1 such that the radiation emitted by the emitter 28 reaches substantially perpendicular to the container bottom 21 and / or substantially parallel to the axis of movement of the container 3, as shown in FIG. Be placed.

  In particular, the emitter 28 and the sensor 27 are arranged with respect to the container bottom 21 so that the radiation emitted by the emitter 28 is reflected towards the sensor 27 by the container bottom 21 according to the principle that the angle of incidence is equal to the reflection angle. The emitter 28 and the sensor 27 are preferably arranged close to each other.

  In the illustrated embodiment, the lower housing part 18 of the atomizer 1 is removed for testing or measurement using the test device 24, or the atomizer 1 is gripped in the holding device 25 without the lower housing part 18. Or accepted. In this way, the scattering of the radiation emitted by the emitter 28 is reduced. However, solutions are also conceivable in which the atomizer 1 is measured or measurable with the lower housing part 18. In particular, solutions are also conceivable in which the atomizer 1 is tested or testable when assembled (completely). For example, the lower housing part or cover 18 can be transparent or transparent to emitted or reflected radiation. The sensor 29 is preferably designed to detect at least part of the radiation emitted by the emitter 28 and / or reflected on the container 3 or the container bottom 21.

As a result of the radiation being reflected on the container 3 or the container bottom 21 and the reflected radiation being detected by the sensor 29, between the side of the measuring device 27 facing the measuring device 27 or the atomizer 1 and the container 3 or container bottom 21 , Or the distance that can vary during the atomization process, and / or the stroke Δs _{stroke of the} container 3 or the distance change in the case of stroke movement.

Other optical measurements or principles such as interferometry, silhouette procedures, and / or camera-based segmentation may be used in addition to or instead of triangulation. In particular, the movement of the container 3 or the container bottom 21, particularly preferably the velocity v _stroke , stroke Δs _stroke , and / or stroke duration Δt _stroke , in addition to or instead of triangulation, interferometry, silhouette procedure, And / or by other optical measurement methods such as camera-based segmentation.

  For example, the test apparatus 24 or the measuring device 27 can have (additional) emitters and (additional) sensors, the container 3 is preferably arranged between the emitters and the sensors and / or the fluid 2 is The shadow or silhouette of the container 3 when dispensed or the movement of the container 3 is illuminated by the emitter so that it is detected by the sensor by a change in the shadow or silhouette.

  According to another embodiment (not shown), the container 3 preferably comprises at least one marking on the side, in particular a line marking, and the movement of the container 3 when the fluid 2 is dispensed is preferably Measured or tracked by its marking and associated (additional) recording devices, especially cameras.

  Preferably, in such an embodiment, the data processing device 31 detects the marking before, during and / or after the fluid 2 is dispensed and / or the container 3 or It is designed to segment the image of the marking, particularly to perform its edge detection.

In addition to or instead of optical measurement methods or principles, mechanical and / or electrical measurement methods or principles can be used. In particular, the movement of the container 3 or the container bottom 21, in particular the velocity v _stroke , the stroke Δs _stroke , and / or the stroke duration Δt _stroke, is mechanical and / or electrical in addition to or instead of the optical measuring method. It can be measured by a typical measurement method.

  For example, the movement and / or position of the container 3 can be detected by at least one tactile sensor or sensor probe before, during and / or after the fluid 2 is dispensed.

  In another embodiment (not shown), the movement of the container 3 or the change in the distance of the container 3 can be measured inductively or by an inductive sensor.

  Preferably, the container 3 in this type of embodiment comprises a conductive material, such as metal, for example on the container bottom 21 and / or the container 3 in this type of embodiment is at least partly metal-like. The inductance which is made of a conductive material and which changes when the container 3 moves relative to the associated sensor or when the distance of the container 3 changes is preferably detected or detectable.

  In another embodiment (not shown), the movement of the container 3 or the change in the distance of the container 3 can be measured capacitively or by a capacitive sensor, when the container 3 is moved relative to the associated sensor or the distance of the container 3 The changing capacitance upon change is preferably detected or detectable.

  Preferably, a plurality of particularly different measurement methods or principles can be combined. Advantageously, in this way any measurement error can be detected and the measurement accuracy can be improved.

Preferably, a stroke path or stroke Δs _{stroke of} about 0.5 mm to 100 mm, particularly preferably 1 mm to 20 mm, especially 4 mm to 12 mm is measured.

  Preferably, when the atomizer 1 is in tension, the distance between the measurement device 27, in particular the side of the measurement device 27 facing the atomizer 1 or the emitter 28, and the atomizer 1 or the container 3 or the container bottom 21 is 5 mm. Greater than or greater than 10 mm, particularly preferably greater than 20 mm or greater than 30 mm, especially greater than 40 mm, and / or less than 200 mm or less than 150 mm, particularly preferably less than 100 mm, especially less than 80 mm. .

  The system 23 or the test apparatus 24 preferably comprises a control device 30, which is designed to control the measurement device 27, in particular the emitter 28 and / or the sensor 29, in an open loop and / or closed loop manner. It is preferable.

  Preferably, the system 23 or the test apparatus 24 includes a data processing device 31 such as a computer, which in particular processes data or data signals such as measured values or measurement signals of the measuring device 27, To store and analyze and / or to target values, in particular target speed, target stroke, and / or target duration, and / or limit values, in particular maximum and / or minimum speed, maximum and / or minimum It is preferably designed to compare against stroke, maximum and / or minimum duration.

  Particularly preferably, the data processing device 31 is such that the measured value detected by the measuring device 27 does not comply with the target value, in particular the target speed, the target stroke and / or the target duration, and / or the maximum and / or minimum speed. To identify a bad atomizer 1 when it is outside a range defined by limits such as maximum and / or minimum stroke, maximum and / or minimum duration, or when the atomizer 1 is defective (automatic Designed to be identified or flagged).

  Particularly preferably, the measuring device 27 is electrically connected or connectable to the control device 30 and / or the data processing device 31.

  Preferably, the system 23 or the test apparatus 24 includes an activation or trigger device 32 such as an actuator, the activation device 32 to activate the atomizer 1 or the locking element 8 or trigger button 8a of the atomizer 1 and / or It is preferably designed to trigger the dispensing of fluid 2.

  Preferably, the activation device 32 is formed as an electric drive. However, other solutions are possible in this case. Optionally, the trigger device 32 comprises a force measuring device (not shown), which triggers in particular for moving the locking element 8 for the purpose of triggering the atomizer 1 or for the purpose of triggering. It is designed to measure the force required to press the button 8a. In that process, the trigger force is measured in particular as a function of the duration of the trigger or activation process.

  Preferably, the activation device 32 is electrically connected to the control device 30 and / or the data processing device 31 and / or controlled by the control device 30 and / or the data processing device 31 and is particularly triggered. be able to.

  Optionally, the system 23 or test device 24 includes a scale (not shown) that is preferably designed to determine the weight of the dispensed fluid 2. Particularly preferably, the scale is integrated into the mount of the atomizer 1 in the test device 24 (not shown). Preferably, the scale is electrically connected to the control device 30 and / or the data processing device 31.

  Preferably, the holding device 25, the measuring device 27, the control device 30, the activation device 32, and / or the scale includes a common housing 33 or the holding device 25, the measuring device 27, the control device 30, the activation device 32, and / or Alternatively, the scale is integrated into the shared housing 33. This allows or facilitates a particularly compact configuration.

  Optionally, the system 23 or test device 24 is preferably a tensioning device (not shown) that is preferably designed to tension the atomizer 1 or the housing part 16 against the inner part 17 or the lower housing part 18. including. Most preferably, the test device 24 can be activated by applying tension to the atomizer 1. Preferably, the tensioning device comprises a measuring device, the measuring device measuring the force required to tension the atomizer 1 and / or loading the energy storage mechanism with the inner part 17 or the lower housing. It is designed to measure the torque that must be overcome to rotate the housing part 16 relative to the part 18. Preferably, the test device 24 has a plurality of test cycles which are constituted by applying tension to the atomizer 1 on the test device 24 and triggering (activating the locking element 8 or the trigger button 8a of the atomizer 1). And is generally designed to be capable of making at least one measurement of proper functionality in an automated fashion during atomization.

  Optionally, system 23 or test apparatus 24 includes a suction device (not shown), or system 23 or test apparatus 24 is connected to a suction device, and the connection to the suction device or suction device is preferably During or after the atomizer 1 is generating aerosol, it is specifically designed to aspirate and / or carry away the aerosol dispensed by the atomizer 1 out of the test device 24.

  Optionally, the system 23 or the test apparatus 24 includes a recording device 34, which optically records or takes an image of the atomizer 1, in particular an image of the aerosol 14, during dispensing, or Preferably, the aerosol 14 is designed to be recorded optically or in the form of an image.

  Preferably, the recording device 34 is electrically connected or connectable to the control device 30 and / or the data processing device 31.

  A “recording device” in the sense of the present invention is a particularly digital, still, photograph such as a video, video sequence, image or photograph, continuous image, still photograph of an object, in particular a fluid 2 or aerosol 14 to be dispensed. In particular optical photographic film or video devices, preferably designed to take, record, generate, process, store, and / or transmit or send optical images is there. Preferably, the recording device in the sense of the present invention is a camera, in particular a film camera or video camera, a webcam, a screen camera, a digital camera or a camcorder and / or a photo camera, and / or a recording device is Including such and / or camera modules.

  In the following, the method according to the invention for testing the proper functionality of the atomizer 1 will be described in more detail.

  The proposed test method is preferably executed by the proposed system 23 or test device 24. In particular, the system 23 or the test device 24 is designed to carry out the proposed method.

  In this test method, the atomizer 1 is tested to check that it is functioning properly and / or for any defects. In particular, it is ascertained whether and / or to what extent the atomizer 1 functions and / or satisfies the predefined requirements or has a predefined function.

  Particularly preferably, a defective atomizer 1 or a malfunctioning atomizer 1 is identified and / or discarded. Preferably, the method is carried out with respect to the atomizer 1 during the production process, in particular during the assembly process or thereafter.

FIG. 4 shows a schematic or ideal curve of the stroke or path traveled by the container 3 as a function of time t. At time t ₁ , the atomizer 1 is preferably activated or the container 3 starts to move and the time t _{3 completes} the stroke movement of the container 3 or the dispensing of the fluid 2.

As shown in FIG. 4, the stroke movement of the container 3, in particular, the stroke Δs _stroke and the stroke duration Δt _stroke can be divided into two sections in principle.

In the first zone t ₁ to t ₂ or s ₁ to s ₂ , the container 3 preferably moves at a higher velocity v _stroke than in the second zone t ₂ to t ₃ or s ₂ to s ₃ . In the first zone, the container 3 preferably moves by _an idle stroke Δs _{stroke, 1} over time Δt _{stroke, 1} . In the first zone, preferably the fluid 2 is not dispensed or atomized, or only a small amount of fluid is dispensed or atomized. This can be attributed in particular to the compression of bubbles that can be present in the atomizer 1, the elastic deformation of the atomizer 1 or the components of the atomizer 1, and the like.

In the second zone following the first zone, the container 3 preferably moves by an effective stroke Δs _{stroke, 2} over time Δt _{stroke, 2} and the fluid 2 is preferably dispensed or atomized. Is done.

Preferably, the idle stroke Δs _{stroke, 1} and / or the time Δt _{stroke, 1} is significantly shorter than the time Δt _{stroke, 2} . Particularly preferably, the time Δt _{stroke, 1} can be ignored compared to the time Δt _{stroke, 2} .

Potential defects in the atomizer 1 and / or those that can be measured, identified, quantified, estimated or indexed by this test method are in particular the strokes Δs _stroke or effective strokes of the container 3 Δs _{stroke, 2} is too short, container 3 velocity v _stroke is too high and / or too low, container 3 idle stroke Δs _{stroke, 1} is too long, and atomizer 1 spray duration Δt _stroke is short Too much and / or too long. In the process, as a functional defect of the atomizer 1, the volume or weight of the fluid 2 leaking during the dispensing of the fluid 2 is too large, and the pressure drop in the atomizer 1, particularly in the supply tube 9 and / or the delivery nozzle 12. Is too large, the volume or weight of dispensed fluid 2 or aerosol 14 is too small, the flow rate of fluid 2 in delivery nozzle 12 is too low, and the rate at which aerosol 14 is released is too low or It is preferred that too high is detected (preferably indirectly). An example of a potential leak source that can be detected based on a shorter spray duration is a poor seal or assembly error when the components defining the fluid path are combined in the atomizer 1. In contrast, deposits or inaccurate positioning in the fluid path that affects function (especially in the filter or nozzle) will be detected based on longer spray durations.

Preferably, the stroke Δs _{stroke of} the container 3, in particular the idle stroke Δs _{stroke, 1} and the effective stroke Δs _{stroke, 2 of} the container 3, the velocity v _{stroke of the} container 3, and the spray or stroke duration Δt _stroke of the atomizer 1 are directly Or indirectly measured by the test method or detected by corresponding measurements. Preferably, the stroke duration Δt _stroke and the slope of the best fit line associated with the stroke transition in the second zone, ie time range t ₂ to t ₃ , measured over time are used as test parameters. .

  Preferably, the measured values (preferably not only the values or data determined on the measuring device 27 but also those determined on other measuring or recording devices of the test apparatus 24) are then preferably Empirical, numerical, theoretical and / or practically determined target values and / or target ranges or limits.

  Preferably, the atomizer 1 is discarded or identified as being at least substantially bad or not functioning (automatically) if the measured value does not comply with the target value and / or does not fall within the target range. Or classified.

  The test device 24 applies tension to a measuring device 27 for measuring the movement of the container 3, for example, a measuring device for measuring the force that activates the scale and / or the trigger button 8a, and / or the atomizer 1. In addition to the measuring device for determining the force required for the measurement, if an additional measuring device (not shown) is included, the value (eg weight or force value) measured thereby is also preferred. Are compared to a predetermined and / or specified target value and / or target range or limit value, and the atomizer 1 identified as defective based on this comparison is preferably discarded. Preferably, the optical, photographic or image data detected by the (optional) recording device 34 is also analyzed and compared with a corresponding set of data or images defined as a limit value. The atomizer 1 identified as defective based on this is discarded.

  Preferably, the atomizer 1 is identified or classified (automatically) as functioning or at least substantially free of defects if the measured value conforms to the target value and / or falls within the target range. .

  In order to test the atomizer 1, the atomizer 1 is preferably gripped or received by the test apparatus 24 or the holding device 25. Particularly preferably, the atomizer 1 is inserted into the hole 26 in the test device 24 or the holding device 25, for example by means of a grip (not shown) or another manipulator (not shown), preferably automatically gripped. Or it is concluded.

  The atomizer 1 preferably includes an energy storage mechanism such as a spring, which is preferably loaded or tensioned in a tensioning step prior to activating the atomizer 1 to dispense aerosol. Is done.

  Preferably, the atomizer 1 is inserted into or received by the test apparatus 24 or holding device 25 when it is already in tension. However, it is also possible that the (non-tensioned) atomizer 1 is first inserted into or received by the test device 24 or holding device 25 and then tensioned.

  In particular, structural solutions are possible in which the test apparatus 24 includes a tension device (not shown), the atomizer 1 or the energy storage mechanism of the atomizer 1 being loaded or tensioned by the tension device. Preferably, the atomizer 1 is positioned above or just before the measuring device 27 or the emitter 28 so that in particular the container 3 or the container bottom 21 can be illuminated.

  Preferably, the measuring device 27 is (next) activated or switched on, preferably by the control device 30 and / or the data processing device 31. However, it is also possible to activate or turn on the measuring device 27 continuously.

  Preferably, the container 3 or the container bottom 21 is illuminated in particular by the measuring device 27 or the emitter 28. Particularly preferably, at least a part of the radiation is reflected by or on the container 3 or the container bottom 21 and is preferably directed at least partly to the sensor 29.

  Particularly preferably, the position of the radiation reflected on the container 3 or the container bottom 21 is detected by a sensor 29 and / or stored therein.

  Preferably, the distance between the container 3 or container bottom 21 and the side of the measuring device 27 facing the measuring device 27 or atomizer 1 and / or the container 3 or container bottom 21 and the measuring device 27 or atomizer 1 The change in distance between the sides of the measuring device 27 is preferably measured by the measuring device 27 when the fluid 2 is dispensed. Preferably, this measurement is performed before, during and after the fluid 2 is dispensed, in other words continuously.

  Preferably, the measurement signal 35 is generated during measurement and / or transmitted to the control device 30 and / or the data processing device 31.

  Particularly preferably, the measurement signal 35 is preferably continuously at a frequency higher than 1 kHz or higher than 2 kHz, particularly preferably higher than 5 kHz or higher than 10 kHz, in particular higher than 20 kHz or higher than 50 kHz. Generated and / or transmitted.

  The measurement signal 35 is preferably reflected on the container 3 or the container bottom 21 with the radiation emitted by the emitter 28 and / or a change in the distance and / or distance between the container 3 or the container bottom 21 and the measurement device 27. A signal having information on the angle and / or angle change between the detected radiation and / or the position and / or position change of the radiation detected by the sensor 29.

Particularly preferably, the measurement signal 35 includes information regarding the stroke Δs _stroke , the velocity v _stroke , and / or the stroke duration Δt _stroke .

  A signal in the sense of the present invention is preferably a means for transmitting information, in particular a (modulated) wave in a conductor, a bit sequence or a packet in the IT sense. In particular, a signal in the sense of the present invention can be transmitted through a transmission medium or by a data connection. Preferably, the information that can be transmitted by the signal is associated with or contained within the signal.

  Preferably, the atomizer 1 is preferably activated by an activation device 32 to dispense the fluid 2. By activating the atomizer 1, the fluid 2 is atomized or the aerosol 14 is formed.

  Optionally, the force required to tension and / or activate the atomizer 1 is preferably measured by a measuring device. Particularly measured is the force required to move the locking element 8 for the purpose of triggering the atomizer 1 or the force required to press the trigger button 8a for the purpose of triggering.

  Preferably, the container 3 or the container bottom 21 has a housing part 16 when the main spring 7 is relaxed or when the fluid 2 is dispensed or the aerosol 14 is formed and / or after the atomizer 1 is activated. Move against. In particular, the container 3 or the container bottom 21 moves in the axial direction toward the delivery nozzle 12. Particularly preferably, the container 3 or the container bottom 21 performs a stroke movement when the fluid 2 is dispensed.

Preferably, the stroke Δs _stroke , the idle stroke Δs _{stroke, 1} , the effective stroke Δs _{stroke, 2} , the stroke duration Δt _stroke , the velocity v _stroke , and / or the acceleration of the container 3 is preferably determined by the measurement signal 35 or the measured value. Determined or calculated by data processing device 31. In addition or alternatively, the pressure drop in the atomizer 1, the flow rate of the fluid 2 in the delivery nozzle 12, and / or the volume or weight of the dispensed fluid 2 is determined by the measurement signal 35 or the measured value, It is preferably determined or estimated by the data processing device 31.

Preferably, the measurement signal 35 or measured value, in particular the stroke Δs _{stroke of the} container 3, the idle stroke Δs _{stroke, 1} , the effective stroke Δs _{stroke, 2} , the duration Δt _stroke , the velocity v _stroke, is determined by the corresponding target value, in particular , Target stroke, target duration and / or target speed and / or limit values, in particular maximum and / or minimum stroke, maximum and / or minimum stroke duration, and / or maximum and / or minimum speed Compared against.

  Preferably, the target values and / or limit values are stored in the data processing device 31 and / or (external) database, which is in particular connected to the database.

  Preferably, optical measurements or images of the fluid 2 or aerosol 14 being dispensed or the spray pattern produced during dispensing are preferably taken by a recording device 34 (shown only schematically in FIG. 3), and The spray mist or spray / aerosol 14 is measured optically.

  Optionally, the spray pattern is transmitted to the data processing device 31 and / or compared with a reference image. In this way, defects in the formation of aerosol clouds or additional defects in the atomizer 1 such as sharply deflected spray mist can be identified, defined and / or evaluated.

  In another aspect of the invention that can be performed independently, the measurement signal 35 or measurement value containing the spray pattern recorded by the recording device 34 or the comparison result of the spray pattern is combined with the reference image.

  In particular, whether the movement of the container 3 corresponds to the spray pattern, or whether the specific movement of the container 3 results in the expected spray pattern, and / or vice versa It is checked whether it matches the 21 expected movements, movement speeds, etc. By combining the available information, it is thus possible in particular to draw conclusions regarding the proper functionality of the pressure generator 5 and / or the delivery nozzle 12.

  Particularly preferably, the system or test system 23 includes a spray parameter measuring device for optically measuring the spray mist or spray, and the recording device 34 is in particular part of the spray parameter measuring device. Preferably, the spray parameter measuring device is connected to the data processing device 31 where the transmitted measurement data is compared with reference data.

  The spray parameter measuring device measures the characteristic properties of the droplet cloud or spray or spray mist dispensed by the atomizer 1. In this case, the measured value is preferably compared with the limit value generated and defined in the system, and the atomizer 1 whose determined measurement value is outside the value range defined in particular by the predefined limit value is Automatically detected as defective.

  According to a preferred embodiment, the operating principle of the spray parameter measuring device is based on the light cutting method. In this regard, the light curtain is cut into a spray mist that is preferably generated using laser light and generated along a defined plane. Preferably, the light curtain plane extends perpendicular to the expected main direction of the spray and / or perpendicular to the longitudinal main axis of the atomizer 1 and / or perpendicular to the direction of movement of the container 3. This cutting plane extends a defined distance from the nozzle opening of the atomizer 1 or is generated at a defined distance across the mouthpiece 13 of the atomizer 1. As the spray mist or spray passes through the light curtain, the light is scattered on the aerosol droplets of the spray mist, and the level of light scattering depends in particular directly on the number of aerosol droplets. As a result, a scattered light image is generated on the light curtain plane. In order to detect scattered light images, the system includes a camera system and / or a recording device 34. Preferably, a plurality of scattered light images are detected over a predefined period and at a predetermined moment (based on a spray fog trigger). Preferably, this period corresponds to the expected spray duration, preferably 1 to 1.5 seconds. The scattered light images are preferably taken at least 4 times in total, and particularly preferably the scattered light images are taken at regular intervals, for example every 0.1 second.

  Preferably, the expected spray cone shape is used as the basis for analysis of the scattered light image (reference definition). As light scatters on this type of conical aerosol cloud, the intensity of the scattered light increases parabolically toward the center of the spray cloud. Accordingly, analysis parameters and associated limit values that match the expected spray profile are defined. Such analytical parameters are, for example, the cumulative scattered light intensity, the location of the intensity center relative to the principal axis, and the intensity distribution or dispersion in the scattered light.

  This kind of spray parameter measurement device identifies quality defects that attribute spray mist formation to, for example, blocked nozzles, incorrectly assembled or further damaged nozzles, or deposits in the nozzle area. Can be monitored.

  Optionally, the weight of the atomizer 1 is preferably detected, in particular by a scale, before the fluid 2 is dispensed, while the fluid 2 is being dispensed and / or after the fluid 2 has been dispensed. Or measured. However, particularly preferably, such a gravimetric measurement is part of a subsequent laboratory test performed on a selected sample of the atomizer 1 that has already been tested, in particular in the test device 24.

  Atomizer 1 and / or system 23 or test device 24 before fluid 2 is dispensed, in particular the measured weight of holding device 25 and atomizer 1 and / or system 23 or test after fluid 2 is dispensed By calculating the difference from the measured weight of the device 24, in particular the holding device 25, the weight of the dispensed fluid 2 can be determined or estimated.

  Optionally, the measured or calculated weight or volume of the dispensed fluid 2 or aerosol 14 is preferably compared with a target value or limit value by the data processing device 31.

  The individual aspects and features of the proposed invention and the method steps described above can be implemented either independently of one another or in any combination.

List of reference numbers 1 Atomizer 2 Fluid 3 Container 4 Fluid chamber 5 Pressure generator 6 Mount 7 Main spring 8 Locking element 8a Trigger button 9 Supply tube 10 Return valve 11 Pressure chamber 12 Delivery nozzle 13 Mouthpiece 14 Aerosol 15 Outside air opening 16 Housing part 17 Inner part 17a Upper part (inner part)
17b Lower part (inner part)
18 Lower housing part 19 Holding element 20 Spring 21 Container bottom 22 Puncture element 23 System 24 Test device 25 Holding device 26 Hole 27 Measuring device 28 Emitter 29 Sensor 30 Control device 31 Data processing device 32 Activation device 33 Housing 34 Recording device 35 Measurement signal s path Delta] s _stroke stroke Delta] s _{stroke, 1} idle stroke Delta] s _{stroke, 2} effective stroke t duration Delta] t _stroke stroke duration v _stroke stroke speed

Claims (19)

A system (23) for testing the proper functionality of an atomizer (1) for dispensing a fluid (2) in the form of an aerosol (14),
Said system (23) comprises an atomizer (1) and a particularly automated test device (24),
Said atomizer (1) comprises a container (3), preferably a replaceable container (3) and a housing part (16) holding said fluid (2), particularly preferably replaceable, said container (3) comprising said fluid (2) 2) movable relative to the housing part (16) for dispensing
The test apparatus (24) comprises a measuring device (27) for measuring the movement of the container (3), in particular the container bottom (21), when the fluid (2) is dispensed,
The system (23) includes a data processing device (31) connected to or connectable to the measurement device (27);
The data processing device (31) analyzes the measurement values detected by the measurement device (27) and / or compares them with target values and / or limit values and / or with respect to the atomizer (1) Designed to preferably automatically identify the atomizer (1) as defective when the measured value detected does not comply with the target value and / or is outside the range defined by the limit value And
The system (23) includes a discharge device, and if the atomizer (1) is detected as defective, it is preferably automatically slid and / or discarded by the discharge device.
A system (23) characterized by that. The measuring device (27) measures the velocity (v _stroke ) of the container (3), the stroke (Δs _stroke ) of the container (3), and / or the duration (Δt _stroke ) of the stroke (Δs _stroke ). The system (23) of claim 1, wherein the system (23) is designed to:   The system (23), in particular the test apparatus (24), in addition to the measuring device (27), measures on the aerosol cloud produced by the atomizer (1) or on the spray fog produced by the atomizer (1). A recording device for generating an image of the aerosol cloud generated by the atomizer (1) or of the spray mist generated by the atomizer (1), comprising a spray parameter measuring device for taking values The system (23) according to any one of claims 1 or 2, characterized by comprising (34).   The spray parameter measuring device and / or the recording device are connected to the data processing device (31) of the system (23), wherein the data processing device (31) is a measured value detected by the spray parameter measuring device or Analyzing the images generated by the recording device and / or comparing them with target values and / or limit values or reference images and / or the measured values or images detected with respect to the atomizer (1) Designed to preferably automatically identify the atomizer (1) as bad when it is not compliant with the target value or reference image and / or is outside the range defined by the limit value or reference image. System (23) according to claim 3, characterized in that.   The spray parameter measuring device generates a light curtain that cuts a defined plane in a spray mist generated by the atomizer (1) or in a cloud formed by the aerosol (14). System (23) according to any one of claims 3 or 4.   6. System (23) according to any one of claims 1 to 5, characterized in that the fluid (2) in the container (3) is a pure liquid, preferably ethanol.   The system (23), in particular the test device (24), activates the holding device (25), the control device (30) and / or the atomizer (1) for holding or gripping the atomizer (1). The system (23) according to any one of the preceding claims, characterized in that it comprises a starting device (32).   Said measuring device (27) is designed as an optical and / or non-contact measuring device and / or comprises an emitter (28), in particular a laser, and a sensor (29), in particular an electronic image converter. A system (23) according to any one of the preceding claims.   The system (23) according to any one of claims 1 to 8, wherein the measuring device (27) comprises or is formed by a laser triangulation sensor system. . A method for testing the proper functionality of an atomizer (1) for dispensing a fluid (2) in the form of an aerosol (14) comprising:
Said atomizer (1) comprises a container (3) and a housing part (16), preferably insertable and particularly preferably replaceable, holding said fluid (2),
The container (3) is moved relative to the housing part (16) to dispense the fluid (2), and the movement of the container (3), in particular the container bottom (21), is Measured and / or analyzed when fluid (2) is dispensed,
The measured value detected when the container (3) moves is analyzed and / or compared with a target value or limit value,
The atomizer (1) is preferably automatically determined to be defective when the measured value detected for the atomizer (1) does not comply with the target value and / or is outside the range defined by the limit value Identified by
In doing so, after being identified as being defective, the atomizer (1) is preferably automatically discarded,
A method characterized by that. Speed (v _stroke), stroke (Delta] s _stroke), and / or the stroke (Delta] s _stroke) duration (Delta] t _stroke) is, is preferably measured by the measuring device (27), and / or wherein preferably said atomizer (1 ) Is preferably analyzed by the data processing device (31) and / or for target values, in particular target speed, target stroke, and / or target duration. 11. A method according to claim 10, characterized in that the method is compared against and / or limit values, in particular maximum and / or minimum speed, maximum and / or minimum stroke, and / or maximum and / or minimum duration. . The atomizer (1) is preferably gripped or fastened by a holding device (25) and / or the atomizer (1) is preferably activated by an activation device (32) to dispense the fluid (2) To be
12. A method according to any one of claims 10 or 11, characterized in that The weight of the dispensed fluid (2) or the weight of the aerosol (14) is preferably measured by a scale, and / or the optical measurement of the fluid (2) or aerosol (14) is preferably a spray. Taken during said dispensing by a parameter measuring device, or an image thereof, preferably taken by the recording device (34), and the detected weight value or detected characteristic spray data is preferably compared with the target value. 13. A method according to any one of claims 10 to 12, wherein the image and / or spray pattern recorded and / or recorded is preferably compared with a reference image. The movement of the container (3) or of the container bottom (21), in particular the speed (v _stroke ), stroke (Δs _stroke ) and / or the movement or stroke of the container (3) or container bottom (21). (Delta] s _stroke) duration (Delta] t _stroke) is, preferably by the measuring device (27), a non-contact manner, wherein the claim 10, characterized in that it is measured optically, and / or by triangulation Item 15. The method according to any one of Items 14.   During said measurement or for that purpose, said container bottom (21) is preferably illuminated by a measuring device (27) and / or especially electromagnetic waves are generated on or by said container bottom (21), in particular said 15. A method according to any one of claims 10 to 14, characterized in that it is reflected on or by the reflective coating of the container (3).   A test device (24) for carrying out the method according to any one of claims 10 to 15.   The test device (24) according to claim 16, characterized in that it is automated.   18. The test apparatus (24) according to any one of claims 16 or 17, wherein the test apparatus (24) is a screening test apparatus.   19. Test apparatus (24) according to any one of claims 16 to 18, characterized in that it is suitable for use in 100% inspection.

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