JP2018530572A - Hair oil composition for the control of hair growth stimulation, hair loss, dandruff and its infection - Google Patents

Abstract

An improved hair oil composition for the control of hair growth stimulation, hair loss, dandruff and its infection. A composition of hair oil comprising an active ingredient of caprylic caprylic acid triglyceride (CCTG), mineral oil, coconut oil, ylang ylang oil, dipropylene glycol, Centella asiatica extract and butylhydroxytoluene. The hair oil composition supports hair growth and scalp relaxation. The hair oil composition also effectively reduces / removes dandruff, thereby controlling hair loss in a subject (eg, not limited to men / women). The composition of the hair oil further demonstrates the properties of cooling effect, hair darkening and hair promotion during continuous use of the hair oil by the subject. Instead, the proposed composition is used to reduce / remove psoriasis.

Description

  Embodiments generally relate to the fields of pharmaceutics, cosmetics and related industries. Embodiments also relate to compositions for the control of hair growth stimulation, hair loss, dandruff and infection thereof. Embodiments relate specifically to an improved oil composition comprising coconut oil, ylang ylang, Centella asiatica extract and butylhydroxytoluene and a method for preparing the same.

  Hair loss / hair loss has become a ubiquitous affliction for humans (both male and female) as the impact of global contamination and lifestyle changes has increased. The most common reasons for radical or premature hair loss / hair loss are genetic predisposition, endocrine disorders, medications, radiation, chemotherapy, chemical exposure, nutritional factors, systemic or local skin disease, stress, childbirth, Alopecia areata and mechanical damage such as tricotylomany, hair styling treatments, hair braids and hairpieces.

  In general, human hair is produced by hair follicles embedded in the scalp. Healthy hair is said to contain 100,000 to 150,000 hairs, each hair of this hair having its own cycle. The life cycle of the hair can be described in three successive physiological stages such as the growth phase, regression phase and resting phase. Growth phase is a stage of hair growth that can last for several weeks to 10 years, and the regression stage is a transient stage of follicular degeneration with root degeneration that can last for several weeks and cessation of hair growth and is resting The period is the stage of hair shedding, where the root that lasts 1 to 5 months moves up towards the surface. Thus, at the end of the resting phase, the hair disappears from the scalp, and this disappearance can extend from days to months before the follicles are reactivated to give new hair in the growing phase.

  Dandruff is a common affliction most commonly associated with the human scalp region. It has been recognized that the skin normally falls off the human skin surface. In general, detaching skin is usually washed off at frequent intervals, and the detachment process is not noticeable. In the scalp, which is not usually washed as often as the rest of the body, the fallen skin tends to accumulate. This skin, together with the natural oil produced by the scalp, forms an environment suitable for bacterial growth, and in fact, certain bacteria are known to be associated with hair loss or hair loss.

  Hair loss causes anxiety and worries that reflect the symbolic and psychosocial importance of hair. Hair loss is a common disorder affecting men and women of all ages, with approximately 50% of men and women suffering from hair loss by 40 years of age. Androgenic alopecia and diffuse alopecia (resting alopecia) are common causes, whereas alopecia areata (massage baldness) affects 1.7% of the population, and “resting alopecia” It develops over several months and is usually not a permanent form of hair loss, and eventually the hair follicles can recover. Topical application of biological response modifiers and antiandrogens is currently available therapy for the management of resting hair loss (HRT can also be used in women), however, with low success rates and associated Adverse effects limit their clinical use.

  Based on the above, there is believed to be a need for improved hair oil compositions for the control of hair growth stimulation, hair loss, dandruff and its infection, as described in more detail herein. .

  The following summary is provided to facilitate an understanding of some of the innovative features inherent in the disclosed embodiments and is not intended to be a complete description. A full appreciation of the various aspects of the embodiments disclosed herein can be gained by taking the specification, claims, drawings, and abstract as a whole.

  Accordingly, one aspect of the disclosed embodiments is to provide improved hair growth products for the control of hair growth stimulation, hair loss, dandruff and its infections.

  Another aspect of the disclosed embodiments is to provide improved hair oil compositions for the control of hair growth stimulation, hair loss, dandruff and its infections.

  A further aspect of the disclosed embodiment is to provide an improved composition comprising coconut oil, ylang ylang, Centella asiatica extract and butylhydroxytoluene and a method for its preparation.

  The foregoing aspects and other disadvantages and advantages can now be achieved as described herein. An improved hair oil composition for the control of hair growth stimulation, hair loss, dandruff and its infection. A composition of hair oil comprising an active ingredient of caprylic caprylic acid triglyceride (CCTG), mineral oil, coconut oil, ylang ylang oil, dipropylene glycol, Centella asiatica extract and butylhydroxytoluene. The hair oil composition supports hair growth and scalp relaxation. The hair oil composition also effectively reduces / removes dandruff, thereby controlling hair loss in a subject (eg, not limited to men / women). The composition of the hair oil further demonstrates the properties of cooling effect, hair darkening and hair promotion during continuous use of the hair oil by the subject. In an alternative embodiment of the present invention, the proposed oil composition is alternatively used to reduce / eliminate psoriasis.

  Clinical trial study results demonstrate the effectiveness of the proposed hair oil composition, which is more effective in controlling dandruff and thereby promoting improved hair growth in subjects Have The hair oil composition comprises 50-60% caprylic acid caprylic acid triglyceride (CCTG), which acts as a hair oil base. This composition is 10-20% mineral oil responsible for humidifying the subject's hair, 25-35% coconut oil for nourishing the hair and scalp, 0 to support hair growth and relaxation of the scalp. 5-0.88% ylang-ylang oil, 0.1-0.2% dipropylene glycol acting as a carrier for aroma, and 0.01-0.05% as anti-dandruff and hair loss preventing agents And 0.1-0.2% butylhydroxytoluene that acts as an antioxidant.

Definitions The following terms shall have the meanings stated therewith.
1. Active ingredient: In this context, the term active ingredient is a complex mixture derived from caprylic caprylic triglyceride (CCTG), mineral oil, coconut oil, ylang ylang oil, dipropylene glycol, Centella asiatica extract and butylhydroxytoluene It is.
2. Oil composition: Oil composition is a caprylic acid caprylic acid triglyceride (CCTG), mineral oil, coconut oil, ylang ylang oil in a defined proportion that effectively reduces dandruff and thereby controls hair loss in the subject. , A mixture of active ingredients of the proposed invention comprising dipropylene glycol, Centella asiatica extract and butylhydroxytoluene.
3. Dandruff: Dandruff is a common chronic scalp condition characterized by peeling of the skin on the scalp. It is the loss of dead skin cells from the scalp. When skin cells die, a small amount of detachment is normal. As the epidermis layer continually replaces itself, the cells are pushed outward and they eventually die and flake off. Dandruff is created when the scalp skin exfoliates excessively. Another cause of dandruff is fungi, especially the abundant fungus Pityrosporum obare.
4). Psoriasis: Psoriasis is a long-term, chronic skin problem that causes skin cells to proliferate too quickly, resulting in thick, white, silvery, or red skin patches. Normally, skin cells grow gradually and detach at about 4 weeks. New skin cells grow and replace the outer layers of the skin as they come off. However, in psoriasis, new skin cells move rapidly to the surface of the skin in days, not weeks. They stack and form a thick patch called a plaque. Patch sizes range from small to large. They most often appear on the knees, elbows, scalp, hands, feet, or waist.

  The accompanying drawings, in which like reference numerals refer to the same or functionally similar elements through different aspects, and are incorporated in and form a part of the specification, further illustrate the invention and Together with a detailed description of the present invention serves to explain the principles of the present invention.

FIG. 1 is a graphical representation of a graph demonstrating the effect of a hair oil composition on a hair population according to the disclosed embodiments. FIG. 2 is a graphical representation of a graph demonstrating the effect of a hair oil composition on hair length according to disclosed embodiments. FIG. 3 is a graphical representation of a graph demonstrating the effect of a hair oil composition on hair density according to the disclosed embodiments.

  The specific values and arrangements discussed in these non-limiting examples can be varied and are cited merely to illustrate at least one embodiment and are not intended to limit its scope .

  The embodiments will now be described more fully hereinafter with reference to the accompanying drawings, in which exemplary embodiments of the invention are shown. The embodiments disclosed herein may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are This disclosure is intended to be thorough and complete, and is provided to fully convey the scope of the invention to those skilled in the art. Like numbers refer to like elements throughout. As used herein, the term “and / or” includes any and all combinations of one or more of the associated listed items.

  The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms “a”, “an”, and “the” are intended to include the plural forms as well, unless the context clearly indicates otherwise. As used herein, the terms “comprises” and / or “comprising” identify the presence of a stated feature, integer, step, operation, element, and / or component. It will be further understood that does not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and / or groups thereof.

  Unless defined otherwise, all terms used herein (including technical and scientific terms) have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries should be construed as having a meaning consistent with their meaning in the context of the related art and are explicitly defined as such herein. It will be further understood that unless otherwise done, it will not be interpreted in an idealized or overly formal sense.

  The present invention relates to an improved hair oil composition for the control of hair growth stimulation, hair loss, dandruff and its infection. A composition of hair oil comprising an active ingredient of caprylic caprylic acid triglyceride (CCTG), mineral oil, coconut oil, ylang ylang oil, dipropylene glycol, Centella asiatica extract and butylhydroxytoluene. The hair oil composition supports hair growth and scalp relaxation. The hair oil composition also effectively reduces dandruff, thereby controlling hair loss in subjects (eg, not limited to men / women).

  The composition of the hair oil further demonstrates the properties of cooling effect, hair darkening and hair promotion during continuous use of the hair oil by the subject. In an alternative embodiment of the present invention, the proposed oil composition is alternatively used to reduce / eliminate psoriasis. It should be noted that the embodiments disclosed therein are merely exemplary embodiments for demonstrating the application of the proposed invention. The embodiments disclosed herein should not be constructed in any limited sense. The proposed oil composition can alternatively be adapted to a wide range of other applications other than dandruff and psoriasis. Those skilled in the art will recognize other applications of the proposed oil composition within the scope of the present invention.

Clinical trial study results demonstrate the effectiveness of the proposed hair oil composition, which is more effective in controlling dandruff and thereby promoting improved hair growth in subjects Have The hair oil composition comprises 50-60% caprylic acid caprylic acid triglyceride (CCTG), which acts as a hair oil base. This composition is 10-20% mineral oil responsible for humidifying the subject's hair, 25-35% coconut oil for nourishing the hair and scalp, 0. 5-0.88% ylang-ylang oil, 0.1-0.2% dipropylene glycol acting as a carrier for fragrance, 0.01-0.05% as anti-dandruff and hair loss preventing agent It further comprises Centella Asia extract and 0.1-0.2% butylhydroxytoluene which acts as an antioxidant. Table 1 illustrates the ratio of active ingredients used in the oil composition.

  FIG. 1 illustrates a graphical representation of a graph 100 demonstrating the effect of a hair oil composition on a hair population according to disclosed embodiments. Results 100 reveal that there is a good increase in the subject's hair population upon continuous use of the test oil over the test period. Prior to the start of the study, the clinician graded 90% of the subject's hair population into the “fair” category and the remaining 10% into the “poor and fair” category, and at the end of the study period, the clinician The subject's hair population was evaluated on a "fair-good-good-good-good" rating. It should be noted that the clinician showed considerable changes in the subject's hair population after 60 days of oil use. There was a steady increase in the average value from 1.55 before use to 3.98 after 90 days of oil use, indicating a significant increase in hair population, from before use to 90 days after use. The difference in the degree of improvement of the hair population is significant at p <0.001.

  FIG. 2 illustrates a graphical representation of a graph 200 demonstrating the effect of a hair oil composition on hair length according to disclosed embodiments. After using the test oil for 90 days, the increase in hair length was evaluated. The data projected on graph 200 demonstrates that clinicians can perceive a good improvement in increasing the subject's hair length when using test oil over the test period.

  Clinicians rated 85% of the subject's hair lengths as a “fair” group before using test oil, but at the end of the study period, clinicians reported improvements in all cases, , 40% of the subjects were fair-good groups, 40% were “good” groups, and the remaining 20% were “good” and “good” groups. An incremental average score from 1.55 before use to 3.98 after 90 days of oil use indicates a steady increase in the subject's hair length in the opinion of the clinician. A value of 53.691, the significance level represented by the Friedman chi-square test, indicates that it is statistically significant at P <0.001. The increase in hair length can be attributed to the effect of oil in inducing the creation of keratinized hair shafts and hair follicles.

  FIG. 3 illustrates a graphical representation of a graph 300 demonstrating the effect of a hair oil composition on hair density, according to disclosed embodiments. The increase in the subject's hair density was evaluated by the clinician. The data projected in the table above demonstrates that there is an increase in hair density of the subject's hair after 60 days of oil use. Clinicians assessed the hair density of 20% of subjects in the “Poor and Fair” group and 80% of the “Fair” group before the start of the study. However, after day 60, there is an increase in hair density in 40% of the participants, and the clinician will improve the hair density of the subject by 35% each while “fair and good” while remaining 5% Rated as “good” group. There is a steady increase in the average rank score from 2.13 prior to use to 3.35 at the end of the 90 day test period. The effectiveness of the test oil in increasing hair density is further supported by a Friedman's chi-square value of 30.797, which is statistically significant at p> 0.001.

  It will be appreciated that variations on those disclosed above, and other features and functions, or alternatives thereof, may be desirably combined in many other different systems or applications. Also, various currently unexpected or unexpected substitutes, modifications, variations or improvements may be subsequently made by those skilled in the art and are intended to be encompassed by the following claims.

Claims (14)

Hair oil composition for hair growth stimulation, hair loss control, dandruff and its infections, the following active ingredients:
Capric acid caprylic acid triglyceride (CCTG);
Mineral oil,
With palm oil,
Ylang ylang oil,
Dipropylene glycol,
A composition comprising Centella Asiatica extract and butylhydroxytoluene.   The composition of claim 1, wherein the hair oil supports hair growth and scalp relaxation.   The composition of claim 1, wherein the hair oil reduces / removes dandruff, thereby controlling hair loss in a subject.   The composition of claim 1, wherein the hair oil demonstrates properties of cooling effect, darkening hair and promoting hair growth during continuous use of the hair oil by the subject.   The composition of claim 1, wherein the hair oil reduces / removes psoriasis on the subject's skin.   The composition of the hair oil is 50-60% caprylic caprylic acid triglyceride (CCTG), 10-20% mineral oil, 25-35% coconut oil, 0.5-0.88% ylang ylang oil, Prepared by mixing 0.1-0.2% working dipropylene glycol, 0.01-0.05% Centella Asiatica extract and 0.1-0.2% butylhydroxytoluene The composition of claim 1.   The composition according to claim 6, wherein the 50-60% caprylic acid caprylic acid triglyceride (CCTG) in the hair oil acts as a base for the hair oil.   The composition according to claim 6, wherein the 10-20% mineral oil in the hair oil acts as a moisturizer for the subject's hair.   7. The composition of claim 6, wherein the 25-35% palm in the hair oil nourishes the hair and scalp.   7. The composition of claim 6, wherein the 0.5-0.88% ylang-ylang oil of the hair oil supports hair growth and relaxation to the scalp.   7. A composition according to claim 6, wherein 0.1 to 0.2% dipropylene glycol of the hair oil acts as a carrier for aroma.   The composition according to claim 6, wherein 0.01 to 0.05% of Centella asiatica extract of hair oil acts as an anti-dandruff agent and an anti-hair oil dropping agent.   The composition according to claim 6, wherein the 0.1 to 0.2% butylhydroxytoluene of the hair oil acts as an antioxidant. A composition for treating hair loss, stimulating hair growth, treating psoriasis and treating dandruff,
50-60% caprylic acid caprylic acid triglycerides;
10-20% mineral oil,
25-35% coconut oil,
0.5-0.88% ylang-ylang oil,
0.1-0.2% dipropylene glycol;
A composition consisting essentially of 0.1-0.2% butylhydroxytoluene.