JP2018147463A - System and method for inspecting risk of developing adverse drug reaction, and computer program - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a system for inspecting the risk of developing adverse drug reactions, the system being able to reduce work required for specifying a drug causing an adverse reaction likely to result from plural drugs prescribed to a patient.SOLUTION: The present invention includes a server comprising: a medication history information DB for storing information on plural drugs prescribed to a patient; a drug information DB for storing drug information containing adverse reaction disease names of drugs; an adverse reaction disease name DB for storing adverse reaction disease names; drug reading means for reading drugs prescribed to a patient, from the medication history information storing means; adverse reaction disease name detecting means for detecting an adverse reaction disease name from the read drug information for each of the plural drugs, on the basis of the adverse reaction disease name DB; determining means for determining whether or not the read plural drugs match the detected adverse reaction disease names; and list creating means for creating the determination results as a list for inspecting adverse reaction developing risks.SELECTED DRAWING: Figure 1

Description

  TECHNICAL FIELD The present invention relates to a drug side effect expression risk screening system, a drug side effect expression risk screening method, and a computer program, and a drug side effect expression related to management of side effect information of a plurality of drugs prescribed to a patient. The present invention relates to a risk scrutiny system, a method for scrutinizing the risk of side effects of drugs, and a computer program.

  A patient may be prescribed a medicine from a plurality of medical institutions or a plurality of doctors, and a situation in which a plurality of medicines are prescribed for the patient is becoming routine. Under such circumstances, various symptoms (inappropriate events) occurring in patients may be caused by side effects of drugs. In order to identify which drug causes a side effect (inappropriate event) among prescribed drugs, it is common to refer to the package insert of the drug. The package insert of the drug describes side effects that may occur due to the drug taken. However, since it is difficult to grasp side effect information in a short time from package inserts of a plurality of prescribed drugs, it is often not easy to identify a causative drug for a side effect (inappropriate event).

  As described above, a system as disclosed in Patent Document 1 is disclosed as a system for checking an overlap of side effects of drugs. The system described in Patent Document 1 is a system for examining whether or not side effects are duplicated for a plurality of drugs, and each drug has a side effect code representing a side effect of the drug for each appearance site or symptom. A detection device provided in the control unit when a plurality of drugs to be inspected are input by the input device, which includes a storage device that stores a drug file associated with each device, an input device, and a control unit that controls the devices. A drug side effect duplication test system is characterized in that, among the plurality of drugs, a duplicate side effect code and a drug having each side effect are detected by an apparatus (see Patent Document 1).

JP 2002-73809 A

  However, since the system proposed in Patent Document 1 uses a side effect code represented by a symbol for each appearance site or symptom for side effects of a drug, successive side effects are sequentially applied to new drug information updated daily. There is a problem that it is necessary to set a code, which is a heavy burden to operate this system.

  Further, the side effect supported in the system proposed in Patent Document 1 is based on duplication of drugs that cause relatively serious symptoms, and is configured on the assumption that such duplication of drugs is checked. It is a thing. However, even if there are side effects with relatively mild symptoms, there are also unpleasant symptoms that patients are aware of in daily life. However, the system proposed in Patent Document 1 exhibits side effects that cause such symptoms. It does not identify the drug that is present.

Therefore, a main object of the present invention is to provide a drug side effect risk screening system that can reduce the task of identifying a drug that causes a side effect that may be caused by a plurality of drugs prescribed to a patient. It is to be.
Another object of the present invention is to provide a drug side effect risk screening system that can alleviate the task of identifying a drug that causes an expected side effect based on a plurality of drugs prescribed to a patient. It is to be.

The drug side effect expression risk screening system according to the present invention stores drug history information storage means for storing a plurality of drug information prescribed to a patient for each patient, and drug information including a drug side effect disease name. Drug information storage means for storing, a side effect disease name storage means for storing a plurality of side effect disease names, a drug reading means for reading a plurality of drugs prescribed to a patient from the drug history information storage means, Side effect disease name search means for searching a side effect disease name from drug information for each of a plurality of read drugs based on a side effect disease name stored in the side effect disease name storage means, and a plurality of read drugs A drug side-action comprising: a determination unit that determines whether or not the name corresponds to the searched side effect disease name; and a list generation unit that generates the determination result as a side effect risk review table It is an expression risk scrutiny system.
The drug side effect expression risk review system according to the present invention includes at least one terminal having at least display means, a system management device, and drug information storage means for storing drug information including a drug side effect disease name. A drug side effect risk review system for drugs comprising: a drug history information storage means for storing a plurality of drug information prescribed to a patient for each patient in either a terminal or a system management device; Side effect disease name storage means for storing the side effect disease name, drug reading means for reading a plurality of drugs prescribed to the patient from the drug history information storage means, and side effects stored in the side effect disease name storage means Based on the disease name, the side effect disease name search means for searching for the side effect disease name from the drug information for each of the plurality of read drugs, and the read plural A side effect expression risk review table that includes a determination means for determining whether or not a drug corresponds to a searched side effect disease name, and a list creation means for creating a determination result as a side effect expression risk review table Is displayed on the display means of the terminal, which is a drug side effect expression risk screening system.
Further, the drug side effect risk screening system for drugs according to the present invention has a function in which the list creation means displays the side effect disease names in descending order of the number of prescribed drugs corresponding to the side effect disease names in the side effect expression risk screening table. It is preferable to have.
Furthermore, the drug side effect risk screening system according to the present invention is based on a period during which a plurality of drugs are prescribed when the drug reading unit reads out a plurality of drugs prescribed for a patient from the drug history information storage unit. It is preferable to have a function of reading out.
Further, in the drug side effect expression risk review system according to the present invention, it is preferable that the list creation means has a function of displaying in order of date and time when the drug is prescribed when the side effect expression risk review table is created.
Furthermore, in the drug side effect risk review system according to the present invention, the drug information stored in the drug information storage means includes information on a side effect event related to the name of the side effect disease, and the information on the side effect event includes a severity classification standard. The side effect disease name search means preferably searches for the side effect disease name based on the severity classification criteria included in the information on the side effect event.
Also, in the drug side effect risk screening system according to the present invention, the drug information stored in the drug information storage means includes information on the side effect event related to the name of the side effect disease, and the information on the side effect event is associated with the body part. The side effect disease name search means preferably searches for a side effect disease name for each body part included in the side effect event information.
The method for examining the risk of developing a side effect of a drug according to the present invention is a method for a computer to examine the risk of developing a side effect of a plurality of drugs. A step of reading a plurality of drugs prescribed for a patient from patient-specific drug information, and a side effect disease name search means based on the side effect disease names stored in the side effect disease name storage means A step of searching for a side effect disease name from drug information for each drug; a step of determining whether the determination means corresponds to a side effect disease name searched for a plurality of read drugs; and a list creation means; And a step of creating a determination result as a side effect expression risk review table.
The computer program concerning this invention is a computer program which has a program code for performing the method for investigating the side effect expression risk of the medicine of the present invention, when a computer program is run with a computer.

According to the drug side effect expression risk screening system according to the present invention, drug history information storage means for storing a plurality of drug information prescribed to a patient for each patient, and drug information including a drug side effect disease name Drug information storage means for storing, side effect disease name storage means for storing a plurality of side effect disease names, and drug reading means for reading a plurality of drugs prescribed to a patient from the drug history information storage means And a side effect disease name search means for searching a side effect disease name from the drug information for each of a plurality of read drugs based on the side effect disease name stored in the side effect disease name storage means, Because it comprises a determination means for determining whether or not the drug corresponds to the searched side effect disease name, and a list creation means for creating a determination result as a side effect expression risk review table, Can reduce the task of identifying drugs that cause side effects that may be caused by multiple medications prescribed to the patient, and may occur based on multiple medications prescribed to the patient. The task of identifying a drug that causes an expected side effect can be reduced.
Further, according to the drug side effect expression risk screening system according to the present invention, the list creation means displays the side effect disease names in descending order of the number of prescribed drugs corresponding to the side effect disease names in the side effect expression risk screening table. If it has a function, it is possible to reduce the work of predicting a side effect that the patient may develop based on the prescribed drug.
Furthermore, according to the drug side effect expression risk review system according to the present invention, when the drug reading unit reads out the plurality of drugs prescribed to the patient from the drug history information storage unit, the period during which the plurality of drugs are prescribed If it has the function of reading out based on the above, it is possible to reduce the work of identifying a drug that causes a side effect that is caused more to the patient.
Further, according to the drug side effect expression risk review system according to the present invention, the list creation means has a function of displaying in order of the date and time when the drug is prescribed when the side effect expression risk review table is created, and further causes the patient to express The work of identifying a drug that causes a side effect can be reduced.
Furthermore, according to the drug side effect expression risk screening system according to the present invention, when the side effects appearing for a plurality of prescribed drugs are displayed so as to be described according to the severity classification criteria, It is possible to save the trouble of sequentially browsing documents, and to easily grasp the side effect disease name for each severity classification standard at a glance.
Further, according to the drug side effect expression risk screening system according to the present invention, when the side effects appearing for a plurality of prescribed drugs are displayed for each body, the package inserts for each drug are sequentially displayed. It is possible to save the time and effort of browsing, and it is possible to easily grasp the side effect disease name for each body at a glance.

According to the present invention, it is possible to provide a drug side effect expression risk screening system that can reduce the work of identifying a drug that causes a side effect that is considered to be caused by a plurality of drugs prescribed to a patient. .
In addition, according to the present invention, there is provided a drug side effect expression risk screening system capable of reducing the work of identifying a drug causing a side effect that is expected to occur based on a plurality of drugs prescribed to a patient. can do.

  The above-described object, other objects, features, and advantages of the present invention will become more apparent from the following description of embodiments for carrying out the invention with reference to the drawings.

It is an illustration figure which shows the structural example of one Embodiment in the side effect expression risk close examination system of the chemical | medical agent concerning this invention. (A) is an illustration figure which shows the structural example of the side effect information processing part of one Embodiment in the side effect expression risk detailed examination system of the medicine concerning this invention, (b) is the side effect expression risk of the medicine concerning this invention It is an illustration figure which shows the structural example of the database part of one Embodiment in a close examination system. It is an illustration figure which shows the structural example of the patient individual treatment related information database of one Embodiment in the side effect expression risk close examination system of the chemical | medical agent concerning this invention. It is a flowchart for demonstrating the processing flow of the preparation process of the side effect expression risk detailed examination table | surface using the side effect expression risk detailed examination system of the chemical | medical agent concerning this invention. It is a figure which shows an example of the preparation process of the side effect expression risk detailed examination table concerning this invention. It is a figure which shows an example of the side effect expression risk detailed examination table concerning this invention. It is a figure which shows the 1st modification of the side effect expression risk review table concerning this invention, (a) is a figure which shows the state in which the name of the side effect disease applicable to each medicine was described, (b) is (a It is a figure which shows the side effect expression risk scrutiny table created based on). It is a figure which shows the 2nd modification of the side effect expression risk scrutiny table concerning this invention, and is a figure which shows the side effect expression risk scrutiny sheet of the severity of class A. It is a figure which shows the 2nd modification of the side effect expression risk scrutinization table concerning this invention, and is a figure which shows the side effect expression risk scrutiny table of the severity class B. It is a figure which shows the 2nd modification of the side effect expression risk scrutiny table concerning this invention, and is a figure which shows the side effect expression risk scrutiny sheet of the severity of class C. It is a figure which shows the 2nd modification of the side effect expression risk scrutiny table concerning this invention, and is a figure which shows the side effect expression risk scrutiny table of the severity of all classes. It is a figure which shows the 3rd modification of the side effect expression risk scrutiny table concerning this invention, and is a figure which shows the side effect expression risk scrutiny sheet displayed according to the body part of the side effect disease.

FIG. 1 is an illustrative view showing a configuration example of an embodiment in a drug side effect expression risk screening system according to the present invention.
The side effect expression risk examination system 10 of the drug identifies the drug that causes the risk of side effects caused by a plurality of drugs prescribed to the patient and the symptoms that are expressed in the patient by introducing this system. It is a system that made it possible to reduce

  The drug side effect expression risk review system 10 uses the system to manage a user terminal 100 for using or managing the side effect review system, a program for managing the system and processing side effect information, and the like. The system management apparatus 200 is connected to each other via a network 300 by wire or wireless.

  The user terminal 100 is a terminal used to use or manage the drug side effect expression risk review system 10 managed by the system management apparatus 200. User terminal 100 includes an input unit 110 and a display unit 120. In addition, a printing unit 130 is connected to the user terminal 100. The user uses the input unit 110 to make a predetermined input to the side effect expression risk review table 400 presented from the system management apparatus 200 on the display unit 120 of the user terminal 100. Then, the user can display the side effect expression risk review table 400 of the desired patient on the display unit 120. Then, the user can print the side effect expression risk review table displayed on the display unit 120 using the printing unit 130.

The user terminal 100 further includes a communication device (not shown) that can be connected to a network 400 such as the Internet, and a personal computer is mainly used. The user terminal 100 may be configured by a mobile terminal such as a mobile phone or a smartphone, or a tablet terminal. In the side effect expression risk review system 10 according to the present invention, the user terminal 100 preferably includes a plurality of terminals.
For the printing unit 130, for example, a printer such as an inkjet printer or a laser printer is used.

  The system management device 200 manages basic patient information, drug information, and the like managed by the drug side effect expression risk review system 10, and the side effect expression risk review from the user terminal 100 to the drug side effect expression risk review system 10. It is a server for accepting requests to display tables. The system management apparatus 200 includes a management unit 210, a side effect information processing unit 220, and a database unit 230. The database unit 230 includes a patient basic information database (hereinafter referred to as patient basic information DB) 232, a drug information database (hereinafter referred to as drug information DB) 234, a side effect disease name database (hereinafter referred to as side effect disease name DB) 236, and individual patients. A therapeutic drug related information database (hereinafter referred to as patient individual therapeutic drug related information DB) 238 is included.

  The system management apparatus 200 includes a central processing unit (not shown), and executes various arithmetic processes in a memory (not shown) storing a program for executing processing in the server and the central processing unit. A RAM (not shown) for temporarily storing programs and data to be used is provided.

  The management unit 210 has a function for managing basic patient information and medicine information managed by the system management apparatus 200. For example, using the user terminal 100, the management unit 210 registers patient basic information in the patient basic information DB 232 constituting the database unit 230, deletes the registered patient basic information, or stores patient basic information. It has functions for editing and changing. Further, the management unit 210 uses the user terminal 100 to register drug information in the drug information DB 234 constituting the database unit 230, delete the registered drug information, or edit / edit the drug information. It has a function to make changes. Furthermore, the management unit 210 uses the user terminal 100 to register the side effect disease name in the side effect disease name DB 236 constituting the database unit 230, delete the registered side effect disease name, or the side effect disease, for example. It has a function to edit / change names. Further, the management unit 210 uses the user terminal 100, for example, to register the individual patient therapy related information in the patient individual therapy related information DB 238 constituting the database unit 230, or the registered patient individual therapy related information. It has a function for deleting information or editing / changing drug information.

As shown in FIG. 2A, the side effect information processing unit 220 includes a drug reading unit 220a, a side effect disease name search unit 220b, a determination unit 220c, and a list creation unit 220d. The side effect information processing unit 220 includes a program for processing the drug reading unit 220a, the side effect disease name search unit 220b, the determination unit 220c, and the list creation unit 220d, and a side effect expression risk review table as shown in FIG. 400 can be created.
The program for creating the side effect expression risk review table 400 includes, for example, a function for accepting input of information for identifying a patient (for example, a patient's name and patient ID), a drug prescribed to the patient, and a drug history information DB 238b. The function to read from, the function to search the side effect disease name from the drug information for each of a plurality of read drugs, and whether or not the read drug corresponds to each searched side effect disease name, the result Is displayed on the side effect expression risk review table 400.

  The side effect information processing unit 220 may read out the medicine prescribed for the patient from the medicine history information DB 238b according to the prescribed period. Further, the side effect information processing unit 220 has a function for displaying a side effect disease name selection window W1 for selecting a side effect disease name as shown in FIG. 5, and based on the selected side effect disease name, The side effect disease name and the drug information may be displayed on the side effect expression risk review table 400 by searching for the side effect disease name from the read drug information for each of the plurality of drugs.

  The program for creating the side effect expression risk review table 400 constituting the side effect information processing unit 220 has a function of clearing a side effect disease name from the side effect expression risk review table 400, and a function of re-entering a prescribed period of the drug. And a function for registering the side effect expression risk review table 400 as side effect expression risk review information and a function for clearing all display of the side effect expression risk review table 400.

In addition, the program for creating the side effect expression risk review table 400 constituting the side effect information processing unit 220 is the side effect disease name in the descending order of the number of prescribed drugs corresponding to the side effect disease name in the side effect expression risk review table 400. It has a function to display.
Furthermore, as necessary, the program for creating the side effect expression risk review table 400 constituting the side effect information processing unit 220 has a function of displaying in order of the date and time when the drug is prescribed to the patient.

  As shown in FIG. 2B, the database unit 230 includes a patient basic information DB 232, a drug information DB 234, a side effect disease name DB 236, and a patient individual treatment drug related information DB 238.

  The patient basic information DB 232 is information for specifying a patient, including basic patient information (patient basic information) such as a patient ID, a patient's name, sex, address, telephone number, and mail address. The patient basic information stored in the patient basic information DB 232 is used for registering the patient basic information, deleting the registered patient basic information, or editing / changing the patient basic information, which the management unit 210 has. It is processed by the function.

  The drug information DB 234 has a function of storing basic information about drugs. This drug information includes information such as a drug name, a period during which the drug is prescribed, a drug price, an identification code, a drug effect, and a side effect disease name.

  The drug information DB 234 also includes information on side effect events related to side effect disease names. Adverse events refer to symptoms, pathologies and diseases. The side effect event information includes information on severity classification criteria. Severity classification criteria are divided into, for example, three classes: class A, class B, and class C. Class A is subjective and objective symptoms. The objective symptom included in Class A is the appearance seen from others. Class B is an objective symptom and is an examination finding, mainly a doctor's judgment. Class C includes dangerous (serious) symptoms or diseases.

Furthermore, the information on the side effect event related to the side effect disease name included in the drug information DB 234 is associated with the body part. The body part is classified into, for example, the whole body, skin, oral cavity, respiratory organs, circulatory organ, liver / kidney, digestive organs, nerves, mind, and eyes.
Side effect symptoms falling under “systemic” include drug shock, fever, sweating, edema, and anemia / bleeding tendency. Side effect symptoms corresponding to “skin” include rash, redness, flushing, swelling and pruritus / eczema. Side effect symptoms corresponding to “oral” include dry mouth, stomatitis, and abnormal taste. Side effect symptoms corresponding to “respiratory organs” include cough / asthma, sputum, dyspnea, and sore throat. Side effect symptoms corresponding to “circulatory organs” include chest pain / chest feeling, blood pressure (rising / lowering), palpitation, hot flashes / hot flashes, and cold / numbness / stiff shoulders of the extremities. Side effect symptoms corresponding to “kidney / liver” include jaundice, difficulty in urination, urinary retention, frequent urination, and residual urine sensation. Side effect symptoms corresponding to “digestive organs” include loss of appetite, nausea / vomiting, abdominal pain, diarrhea / constipation, heartburn, and abdominal fullness. The side effect symptom corresponding to “nerve” is headache, dizziness / lightheadedness, sleepiness, tremor / convulsion, and limb pain / back pain. Side effect symptoms corresponding to “mental” include hallucinations, depression, weakness / malaise, anxiety / excitement, and disturbance of consciousness. Side effect symptoms corresponding to “eye” include abnormal visual angle and conjunctival hyperemia.

The drug information corresponds to, for example, a package insert created by a pharmaceutical company corresponding to an instruction manual for each drug. The drug information is used when creating a side effect expression risk screening table in the drug side effect expression risk screening system 10 according to the present invention. The package insert is a document that contains product information for drug users, doctors, and pharmacists, including side effects information, warnings, precautions, item specifications, and other important matters.
The drug information DB 234 may use a database outside the drug side effect expression risk review system 10.

  The side effect disease name DB 236 has a function of storing information on side effect disease names used in the drug side effect expression risk review system 10. That is, the side effect disease name stored in the side effect disease name DB 236 is obtained from the drug information for each of the plurality of drugs read out by the program for creating the side effect expression risk review table 400 constituting the side effect information processing unit 220. Used to search for side effect disease names. Further, the side effect disease name DB 236 is used to unify various expressed side effect disease names included in the drug information DB 234 into predetermined expressions.

  As shown in FIG. 3, the individual patient treatment related information DB 238 further includes a brought medicine discrimination record database (hereinafter referred to as a brought medicine discrimination record DB) 238 a, which can manage information for each patient, and a medicine history. An information database (hereinafter referred to as drug history information DB) 238b and a side effect expression risk review information database (hereinafter referred to as side effect expression risk review information DB) 238c are included.

  The brought medicine discrimination record DB 238a has a function of storing information related to the result of the discrimination made by the patient with respect to the medicine brought by the outpatient department. The information regarding the discrimination result includes, for example, the name of the drug brought in, information about whether or not to continue, the expiration date of the brought-in drug, a substitute drug, and the like.

  The drug history information DB 238b has a function of storing information on drugs prescribed to patients. The information on the prescribed medicine includes the medicine name, identification symbol, dosage usage, period of prescription of the medicine (the day when it was prescribed, the day when the prescription was completed), and the like.

  The side effect expression risk review information DB 238c has a function of storing the side effect expression risk review table created by the drug side effect expression risk review system 10 according to the present invention as side effect expression risk review information.

  Next, an example of side effect information processing in the drug side effect expression risk review system 10 in the present embodiment will be described.

(Processing of side effect expression risk review table, etc.)
Next, based on FIG. 4, processing for creating a side effect expression risk review table from the user terminal 100 will be described by the user using the drug side effect expression risk review system 10 according to the present invention.
FIG. 4 is a flowchart for explaining the processing flow of the side effect expression risk review table creation process using the drug side effect expression risk review system according to the present invention. FIG. 5 is a diagram showing an example of a side effect expression risk review table according to the present invention. FIG. 6 is a diagram showing an example of a side effect expression risk review table according to the present invention.

  As shown in FIG. 4, first, a patient name is input from the user terminal 100 in order to identify a patient (step S101). Subsequently, in order to read out the medicine prescribed for the inputted patient name, the prescribed period is inputted (step S102). Then, the medicine corresponding to the input period is read from the medicine history information DB 238b (step S103).

  Subsequently, a desired side effect disease name is selected from the side effect disease name DB 236 storing a plurality of side effect disease names (step S104). At this time, as shown in FIG. 5, in order to select a side effect disease name, the side effect disease name is displayed in the side effect disease name selection window W1. Further, when selecting a side effect disease name, the side effect disease name is selected from the side effect disease name selection window W1 until the selection is completed (step S105).

  Then, based on the selected side effect disease name, the side effect disease name is searched from the drug information for each of the plurality of read drugs (step S106). Here, if the search for the side effect disease name is not completed for the plurality of read out drugs, the search is performed until the search is completed (step S107). If completed, it is determined whether or not the read out drug corresponds to each searched side effect disease name, and the result is displayed in the side effect expression risk review table 400 (step S108).

Furthermore, if it is desired to select a side effect disease name again from the beginning, the side effect disease name can be cleared from the side effect expression risk review table 400 (step S109), and a side effect disease name clear process is executed (step S110). ).
Furthermore, a plurality of drugs to be displayed on the side effect expression risk review table 400 can be changed by re-entering the period for which the drugs are prescribed (step S111).
Subsequently, when registering the created side effect expression risk review table 400 (step S112), registration processing is executed in the side effect expression risk review information DB 238c as side effect expression risk review information (step S113).
Further, when printing the side effect expression risk review table 400 (step S114), the printing process is executed and printed by the printing unit 130 (step S115).
Subsequently, when clearing all the contents of the side effect expression risk review table 400, clear all display is selected (step S116), and clear all display processing is executed (step S117). Otherwise, the processing based on the drug side effect expression risk review system 10 ends.

  In step S102 of the side effect expression risk review table shown in FIG. 4, the period of the drug prescribed to the patient is input. However, the present invention is not limited to this, and this step is omitted. Whether or not the side effect disease name is applicable to all of the plurality of drugs prescribed for the drug may be processed.

  In step S104 of the side effect expression risk review table shown in FIG. 4, a necessary side effect disease name is selected from the side effect disease name selection window W1, but the present invention is not limited to this. By collating the side effect disease name included with the side effect disease name DB 236, without selecting the side effect disease name, that is, omitting the processing of step S104 and step S105 and searching all the side effect disease names, All searched side effect disease names may be displayed on the side effect expression risk review table 400. At this time, the result of whether or not the side effect disease name corresponds to the medicine prescribed by the patient may be displayed together.

Next, an example of the configuration of the side effect expression risk review table 400 will be described.
As shown in FIG. 5 and FIG. 6, the side effect expression risk review table 400 is composed of a basic information area R1, a drug name description area R2, a side effect disease name description area R3, a determination result description area R4, and an instruction button installation area R5. The

  Basic information about the patient is displayed in the basic information area R1. As basic information about a patient, for example, information of a patient ID, a patient name, a sex, a ward, and an attending physician is displayed. In addition, information such as the update date and time of the side effect expression risk review table is also displayed as necessary.

  In the medicine name description area R2, names of a plurality of medicines prescribed for the patient in a predetermined period are displayed. When the drug name is displayed on the side effect expression risk review table 400, the date and time when the drug is prescribed may be displayed from the top in order of the use date and time of the system 10.

In the side effect disease name description area R3, the name of the side effect disease included in the drug information of the prescribed drug is displayed. At this time, when the drug and the side effect disease name are collated, the side effect disease names determined to be applicable may be displayed from the left in the descending order.
In addition, when the appearance frequency of the side effect disease name is the same, it is possible to select and display any of the first appearing word order, Japanese alphabetical order, and random order.

  In the determination result description area R4, a result determined to be applicable when the drug and the side effect disease name are collated is displayed. For example, “O” is displayed when applicable, and “−” is displayed when not applicable. Of course, the display method when applicable or not applicable is not limited to this.

  In the instruction button installation region R5, buttons necessary for operating the side effect expression risk review table 400 are displayed. The buttons necessary for the operation are, for example, “side effect search button”, “all clear button”, “side effect name clear button”, “registration button”, and “print button”.

  According to the drug side effect expression risk review system 10 according to the present embodiment, the drug includes the side effect information processing unit 220 configured by a program for creating the side effect expression risk review table 400. The program for creating has a function of accepting input of a patient name, a function of reading out a medicine prescribed to a patient from the medicine history information DB 238b according to a prescribed period of the medicine, a side effect disease name as shown in FIG. A function for displaying a side effect disease name selection window W1 for selecting a drug, a function for searching a side effect disease name from drug information for each of a plurality of read drugs based on the selected side effect disease name, and reading It is determined whether or not the issued drug falls under each searched side effect disease name, and the result is displayed in the side effect expression risk review table 400 The ability to identify drugs that cause side effects that may be caused by multiple drugs prescribed to the patient, and is prescribed to the patient. It is possible to reduce the work of identifying a drug that causes a side effect that is expected to occur based on a plurality of drugs.

  In addition, according to the drug side effect expression test system 10 according to the present invention, a program for creating the side effect expression risk review table 400 which is a list creation means is provided in the side effect expression risk review table. If it has a function of displaying side effect disease names in descending order of the number corresponding to the name, it is possible to reduce the work of predicting side effects that may occur based on the drug prescribed by the patient.

  Furthermore, according to the drug side effect expression test system 10 according to the present invention, the function of reading out the drug as the drug reading means according to the prescribed period is obtained by retrieving a plurality of drugs prescribed for the patient from the drug history information DB 238b. When reading, having a function of reading out a plurality of medicines based on a prescribed period, it is possible to reduce the work of identifying a medicine that causes a side effect that is caused to the patient.

  In addition, according to the drug side effect expression risk review system 10 according to the above-described embodiment, a program for creating the side effect expression risk review table 400 which is the list creation means list creation means is prescribed to the patient. Having the function of displaying in order of date and time can further reduce the work of identifying a drug that causes a side effect developed in a patient.

  Next, a first modification of the side effect expression risk review table 400 will be described. For example, a modified example of the side effect expression risk review table 400 may be configured as a side effect expression risk review table 400A as shown in FIG.

FIG. 7 is a view showing a first modification of the side effect expression risk review table according to the present invention, and FIG. 7 (a) is a view showing a state in which the name of a side effect disease corresponding to each drug is described, FIG.7 (b) is a figure which shows the side effect expression risk close examination table created based on Fig.7 (a).
In this modification, a program for creating a side effect expression risk review table 400A, which is a drug reading unit 220a, a side effect disease name search unit 220b, a determination unit 220c, and a list creation unit 220d that constitute the side effect information processing unit 220, is shown in FIG. As shown in FIG. 7 (a), based on the selected side effect disease name, the result searched by the function for searching the side effect disease name from the drug information for each of the plurality of read out drugs is used as the side effect expression risk review table. 400A further includes a function for displaying each medicine.
Then, as shown in FIG. 7 (b), the program for creating the side effect expression risk review table 400A determines whether or not the read drug corresponds to each searched side effect disease name, It has a function for displaying the results on the side effect expression risk review table 400A.

According to the side effect expression risk review table 400A as shown in FIG. 7, the side effect expression risk review table 400 shown in FIG.
In other words, displaying the side effects that appear for a plurality of prescribed drugs can save the trouble of sequentially browsing the package inserts of each drug, and the name of the side effect disease for each drug at a glance. It can be easy to grasp.

  Next, a second modification of the side effect expression risk review table 400 will be described. As a modified example of the side effect expression risk review table 400, a side effect expression risk review table 500A to 500D as shown in FIGS.

  FIG. 8 is a diagram showing a second modification of the side effect expression risk review table according to the present invention, and is a diagram showing a side effect expression risk review table of class A severity. FIG. 9 is a diagram showing a second modification of the side effect expression risk review table according to the present invention, and is a diagram showing a side effect expression risk review table of severity class B. FIG. 10 is a diagram showing a second modification of the side effect expression risk review table according to the present invention, and is a diagram showing a side effect expression risk review table of severity class C. FIG. 11 is a diagram showing a second modification of the side effect expression risk review table according to the present invention, and is a diagram showing a side effect expression risk review table of all classes of severity.

In the second modification, first, a side effect expression risk review table 500A that is a drug reading unit 220a, a side effect disease name search unit 220b, a determination unit 220c, and a list creation unit 220d constituting the side effect information processing unit 220 is created. The program is processed in accordance with the severity classification criteria information (class A) included in the side effect event information related to the side effect disease name. That is, in the function of searching for the side effect disease name from the drug information for each of a plurality of drugs read out in the side effect information processing unit 220, the side effect disease name whose severity classification criteria included in the side effect event information is class A is searched. Is done. Accordingly, as shown in FIG. 8, the side effect expression risk review table 500A displays the name and drug of the side effect disease whose severity classification criteria is class A.
Similarly, a program for creating the side effect expression risk review tables 500B to 500D, which is the drug reading unit 220a, the side effect disease name search unit 220b, the determination unit 220c, and the list creation unit 220d that constitute the side effect information processing unit 220, When a side effect disease name whose severity classification criteria included in the side effect event information is class B is searched in the function of searching for the side effect disease name from the read drug information for each of the plurality of drugs in the information processing unit 220 As shown in FIG. 9, the adverse reaction risk review table 500 </ b> B displays the side effect disease name and drug whose severity classification criteria is class B, and a plurality of drugs read by the side effect information processing unit 220. In the function of searching for a side effect disease name from each drug information, the severity classification standard included in the side effect event information is a subclass of class C. When the disease name is retrieved, as shown in FIG. 10, the adverse reaction risk review table 500C displays the adverse reaction disease name and drug whose severity classification criteria is class C, and the adverse reaction information processing unit 220. In the function of searching for the side effect disease name from the drug information for each of the plurality of read out drugs in FIG. 11, when the severity classification criteria included in the side effect event information are searched for all the side effect disease names, FIG. As shown in the table, the side effect expression risk review table 500D displays side effect disease names and drugs whose severity classification criteria are all classes.

The name of the side effect disease searched for by class is displayed in the side effect disease name description region R3 ′ of the side effect expression risk review tables 500A to 500D. That is, the side effect disease name description region R3 ′ of the side effect expression risk review table 500A displays the class A side effect disease name, and the side effect disease name description region R3 ′ of the side effect expression risk review table 500B displays the class B side effect. The name of the disease is displayed, the side effect disease name description region R3 ′ of the side effect expression risk review table 500C is displayed with the name of the side effect disease of class C, and the side effect disease name description region R3 ′ of the side effect expression risk review table 500D is All class A side effect disease names are displayed.
In each class, when the appearance frequency is the same, any one of first word order, Japanese alphabetical order, and random order can be selected and displayed.

According to the side effect expression risk review tables 500A to 500D as shown in FIGS. 8 to 11, the side effect expression risk review table 400 shown in FIG. 6 has the effects and the following effects.
In other words, if the side effects that occur for multiple prescribed drugs are displayed so as to be described according to the severity classification criteria, it is possible to save the trouble of browsing the package inserts of each drug one by one. It can make it easier to identify the names of side-effect diseases for each severity classification standard.

  Next, a third modification of the side effect expression risk review table 400 will be described. As a modified example of the side effect expression risk review table 400, a side effect expression risk review table 600 as shown in FIG.

  FIG. 12 is a diagram showing a third modification of the side effect expression risk review table according to the present invention, and is a diagram showing a side effect expression risk review table displayed for each body part of a side effect disease.

In the third modification, first, a side effect expression risk review table 600 that is a drug reading unit 220a, a side effect disease name search unit 220b, a determination unit 220c, and a list creation unit 220d that constitute the side effect information processing unit 220 is created. The program is processed according to the information on the body part included in the information on the side effect event regarding the side effect disease name. That is, in the function of searching for the side effect disease name from the read drug information for each of the plurality of drugs in the side effect information processing unit 220, the side effect disease name for each body part included in the side effect event information is searched. Therefore, as shown in FIG. 12, the side effect expression risk review table 600 displays the side effect disease name and drug for each body part. The side effect disease name searched for each body part is displayed in the side effect disease name description region R3 ″ of the side effect expression risk review table 600.
When the frequency of appearance of the side effect disease name displayed for each body part is the same, it is possible to select and display any of the first word order, alphabetical order, or random order.

According to the side effect expression risk scrutiny table 600 as shown in FIG. 12, the side effect expression risk scrutiny table 400 shown in FIG. 6 has the effects as well as the following effects.
In other words, displaying the side effects that occur for multiple prescribed drugs in a way that is described by body can save you the trouble of browsing the package inserts for each drug in sequence, and the side effect disease for each body at a glance. The name can be easily understood.

  Moreover, this invention is not limited to the said embodiment, In the range of the summary, it deform | transforms variously.

For example, in the drug side effect expression risk review system 10, the user terminal 100 and the system management device 200 are configured separately, but the present invention is not limited to this, and these may be provided in the same device. . That is, the user terminal 100 may be provided so as to include a part or all of the functions of the system management apparatus 200, or part or all of the functions of the user terminal 100 in the system management apparatus 200. It may be provided so as to include the following configuration.
Also, a part of the configuration of the system management unit 200 may be provided as an external device that configures the drug side effect expression risk review system 10.

  Furthermore, the side effect expression risk review tables 400, 400A, 500A to 500D and 600 shown in FIGS. 5 to 12 are examples, and the configuration thereof may be changed as appropriate within the scope of the present invention.

  As described above, according to the present invention, it is possible to provide a drug side effect risk review system that can provide effective advice to a patient by a doctor, a pharmacist, or the like.

DESCRIPTION OF SYMBOLS 10 Drug side effect expression risk detailed examination system 100 User terminal 110 Input part 120 Display part 200 System management apparatus 210 Management part 220 Side effect information processing part 220a Drug reading part 220b Side effect disease name search part 220c Judgment part 220d List creation part 230 Database part 232 Patient basic information database 234 Drug information database 236 Side effect disease name database 238 Patient individual treatment related information database 238a Brought-in drug discrimination record database 238b Drug history information database 238c Side effect expression risk review information database 300 Network 400, 400A, 500A, 500B, 500C, 500D, 600 Side effect risk assessment table R1 Basic information area R2 Drug name description area R3, R3 ′, R3 ”Side effect disease name Mounting region R4 determination result described region R5 instructing button installation region W1 side effects disease name selection window

Claims (9)

Medicine history information storage means for storing a plurality of drug information prescribed to a patient for each patient;
Drug information storage means for storing drug information including a side effect disease name of the drug;
A side effect disease name storage means for storing a plurality of side effect disease names;
Drug reading means for reading a plurality of drugs prescribed to the patient from the drug history information storage means,
Based on the side effect disease name stored in the side effect disease name storage means, the side effect disease name search means for searching the side effect disease name from the drug information for each of the plurality of drugs read out,
Determining means for determining whether or not the plurality of read out drugs correspond to the searched side effect disease name;
List creation means for creating the determination result as a side effect expression risk review table;
A system for examining the risk of developing side effects of drugs. A drug side effect risk screening system comprising at least one terminal having at least display means, a system management device, and drug information storage means for storing drug information including a drug side effect disease name. ,
Either the terminal or the system management device,
Medicine history information storage means for storing a plurality of drug information prescribed to a patient for each patient;
A side effect disease name storage means for storing a plurality of side effect disease names;
Drug reading means for reading a plurality of drugs prescribed to the patient from the drug history information storage means,
Based on the side effect disease name stored in the side effect disease name storage means, the side effect disease name search means for searching the side effect disease name from the drug information for each of the plurality of drugs read out,
Determining means for determining whether or not the plurality of read out drugs correspond to the searched side effect disease name;
List creation means for creating the determination result as a side effect expression risk review table;
Including
The side effect expression risk review system for drugs, wherein the prepared side effect expression risk review table is displayed on the display means of the terminal. The list creation means includes:
The drug side effect expression risk screening system according to claim 1 or 2, which has a function of displaying side effect disease names in descending order of the number of prescribed drugs corresponding to the side effect disease names in the side effect expression risk review table. . The drug reading means includes
4. The device according to claim 1, having a function of reading out a plurality of medicines prescribed to the patient from the medicine history information storage unit based on a period during which the plurality of medicines are prescribed. A system for examining the risk of developing side effects of the described drugs. The list creation means includes:
The drug side effect expression risk review system according to any one of claims 1 to 4, which has a function of displaying in order of date and time when the drug is prescribed when the side effect expression risk review table is created. The drug information stored in the drug information storage means includes information on a side effect event related to a side effect disease name, the side effect event information includes a severity classification criterion,
The side effect disease name search means includes:
6. The drug side effect risk screening system according to claim 1, wherein a name of a side effect disease is searched based on the severity classification criteria included in the information of the side effect event. . The drug information stored in the drug information storage means includes information on a side effect event related to a side effect disease name, and the information on the side effect event is associated with a body part,
The side effect disease name search means includes:
6. The drug side effect expression risk screening system according to any one of claims 1 to 5, wherein a name of a side effect disease for each body part contained in the side effect event information is searched. A computer is a method for examining the risk of developing side effects of a plurality of drugs,
A step of reading out, from the patient-specific drug information, a plurality of drugs prescribed to the patient stored in a patient-specific drug information storage unit;
A step of searching for the side effect disease name from the drug information for each of the plurality of drugs read based on the side effect disease name stored in the side effect disease name storage unit;
A step of determining whether the determination means corresponds to the searched side effect disease name for the plurality of read out drugs;
A list creating means creating the determination result as a side effect expression risk review table;
A method for examining the risk of developing side effects of a drug.   A computer program having program code for performing the method of claim 8 when the computer program is executed on a computer.

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