JP2018094243A - Blood circulation system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a blood circulation system, when a necessity for increasing/decreasing a blood transmission flow rate arises due to a situation during an operation, capable of efficiently and stably circulating the blood in the blood circulation system including a reservoir.SOLUTION: The blood circulation system includes: a reservoir 102; a liquid level sensor 102S for detecting a liquid level of the reservoir 102; a blood removal flow rate sensor 111; a roller pump 120; and a control part 140 for interlockedly controlling the transmission blood flow rate of the roller pump 120 with respect to the blood removal flow rate. When the liquid level of the reservoir 102 is lower than a reference liquid level, the control part 140 decreases the transmission blood flow rate and, when the liquid level of the reservoir 102 is higher than the reference liquid level, increases the transmission blood flow rate.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a blood circulation system that circulates blood that has been removed by a blood pump.

  As is well known, an artificial heart-lung machine and a blood circulation system for auxiliary circulation are widely used as needed because the heart is stopped or close to being stopped during or after surgery such as heart surgery. .

Conventionally, in order to operate a heart-lung machine, it is common for a clinical engineer to adjust blood flow by manual operation based on a doctor's instruction.
When a clinical engineer adjusts the blood flow rate, for example, while checking the degree of blood removal and the patient's arterial pressure, manually adjust the flow rate of each line and the rotation speed of the blood pump (roller pump, centrifugal pump). The operation requires complex and sophisticated technology.

  In view of this, a technique for adjusting the blood flow rate by deforming it with a blood removal line in order to accurately and easily adjust the blood flow rate with the oxygenator is disclosed (for example, Patent Document 1). reference.).

  In addition, the blood removal regulator control unit and the blood supply regulator control unit are interlocked, and either the blood removal regulator control unit or the blood supply regulator control unit is operated to adjust the blood removal rate and the blood flow rate simultaneously. A technique for efficiently adjusting the blood flow rate in an oxygenator is disclosed (for example, see Patent Document 2).

  However, since the amount of blood to be deflated varies depending on the situation of the operation, etc., even if the techniques described in Patent Documents 1 and 2 are used, blood can be rapidly and stably delivered according to the amount of deflated blood. Is not easy.

  Therefore, a blood circulation system has been developed that can stably circulate blood at an appropriate flow rate even if the blood flow is fluctuating by synchronizing the blood flow of the blood pump with the blood flow. (For example, refer to Patent Document 3).

JP-A-62-027966 JP 2006-020712 A Japanese Patent No. 5839212

However, for example, when blood that has been bleed during surgery is drawn into the reservoir, the amount of blood lost from the body due to bleed, regardless of the amount of blood removed, is checked for the degree of blood removal and the patient's arterial pressure. However, it may be desirable to send blood to the patient.
In addition, when the blood flow rate is controlled in conjunction with the blood flow rate, if the blood flow rate is too small or too large due to the operating conditions, etc., it is desirable to increase or decrease the blood flow rate and adjust it accordingly. There is a case.

  Thus, when increasing or decreasing the blood flow rate depending on the situation during the operation, it is necessary to adjust the blood flow rate so that a large burden is not generated on the patient.

  On the other hand, if the blood flow rate is increased when the blood flow rate is low, the liquid level in the reservoir may decrease too much and air may be mis-fed. Since the liquid level in the reservoir may rise and overflow, it is necessary to prevent air misdelivery or overflow.

  The present invention has been made in consideration of such circumstances, and in a blood circulation system equipped with a reservoir, when there is a need to increase or decrease the blood flow rate depending on the situation during surgery, the present invention is efficient and stable. An object of the present invention is to provide a blood circulation system that can circulate blood.

In order to solve the above problems, the present invention proposes the following means.
The invention according to claim 1 is a blood circulation system that is connectable to a human body and sends blood that has been removed to the human body by means of a blood pump, and a reservoir that temporarily stores the removed blood; A reservoir liquid level detection sensor for detecting the liquid level of the reservoir, a blood removal line for transferring the blood that has been removed to the reservoir, and a blood removal amount measuring means that is provided in the blood removal line and measures the blood removal amount; A blood supply line for transferring blood from the reservoir to the human body, a blood supply pump for transferring blood through the blood supply line, and a blood flow rate of the blood pump within a specific range with respect to the blood removal rate A control unit for controlling blood feeding, and when the liquid level of the reservoir is lower than a reference liquid level, the control unit reduces the blood flow rate of the blood pump and the liquid level of the reservoir is the reference level. If the liquid level is higher, the blood pump Characterized in that it is configured for increasing the blood feeding flow.

According to the blood circulation system according to the present invention, the control unit controls the blood flow of the blood pump in conjunction with the blood removal rate within a specific range with respect to the blood flow loss, and the liquid level in the reservoir is lower than the reference liquid level. In this case, the blood flow rate of the blood pump is decreased. When the liquid level in the reservoir is higher than the reference liquid level, the blood flow rate of the blood pump is increased. Therefore, the blood flow rate can be adjusted by the blood in the reservoir.
As a result, when there is a need to increase or decrease the blood flow rate depending on the situation during surgery, blood circulation can be performed efficiently and stably.

  In this specification, linked blood flow control within a specific range with respect to the blood flow rate of the blood pump is to control the blood flow rate within the range set for the blood flow rate. That is, it can be expressed by a flow rate difference (for example, an upper limit flow rate difference or a lower limit flow rate difference) or a ratio with respect to the blood flow removal rate. This includes the case where the blood flow rate and the blood flow rate are synchronized (equalized).

  Further, in this specification, the reservoir liquid level detection sensor refers to a sensor capable of detecting at least the blood level, for example, an optical sensor that is attached to the outer surface of the reservoir body and detects the liquid level, and an ultrasonic wave In addition to sensors and capacitance sensors, various liquid level sensors capable of detecting the liquid level of blood are included. A sensor capable of detecting the displacement of the liquid level continuously or at a plurality of positions may be applied.

  Further, in this specification, the reference liquid level refers to a liquid level used as a reference when increasing or decreasing the blood flow rate.

  The invention according to claim 2 is the blood circulation system according to claim 1, further comprising reference liquid level setting means for adjusting the reference liquid level detected by the reservoir liquid level detection sensor. And

  According to the blood circulation system of the present invention, the reference liquid level setting means is provided, and the reference liquid level detected by the reservoir liquid level detection sensor can be set at an arbitrary position. The reference liquid level can be set automatically.

  In this specification, the reference liquid level setting means is a means for setting the reference liquid level detected by the reservoir liquid level detection sensor to an arbitrary position. For example, the reservoir liquid level detection sensor is detachable. The attachment means (for example, an adhesive tape, a slide rail, a slide rail, an attachment screw, etc.) that can be attached at any position is included. Note that the reference liquid level may be set by a signal without moving the sensor.

  A third aspect of the present invention is the blood circulation system according to the first or second aspect, in which the control unit feeds the blood pump until the liquid level in the reservoir reaches the reference liquid level. It is configured to increase / decrease blood flow.

  According to the blood circulation system of the present invention, the control unit controls increase / decrease of the blood flow rate of the blood pump until the liquid level of the reservoir reaches the reference liquid level. Can be switched to linked blood feeding control. Further, it is possible to prevent the liquid level in the reservoir from being excessively lowered and prevent air from being erroneously sent, and to prevent the liquid level in the reservoir from rising and overflowing.

  According to the blood circulation system of the present invention, in a blood circulation system having a reservoir, blood circulation can be efficiently and stably performed when it is necessary to increase or decrease the blood flow rate depending on the situation during the operation. .

1 is a circuit diagram illustrating a schematic configuration of a heart-lung machine according to an embodiment of the present invention. It is a longitudinal section explaining a schematic structure of a reservoir concerning one embodiment of the present invention. It is a conceptual diagram explaining attachment of the liquid level sensor with respect to the reservoir | reserver which concerns on one Embodiment of this invention. It is a block diagram explaining the schematic structure of the control part of the heart-lung machine which concerns on one Embodiment of this invention. It is a figure explaining the operation | movement procedure of the heart-lung machine which concerns on one Embodiment of this invention, and is a flowchart in the case of performing the interlocking blood-feeding control which makes a blood-flow rate interlock | cooperate with respect to a blood-removal amount. It is a figure explaining the operation | movement procedure of the heart-lung machine which concerns on one Embodiment of this invention, and is a flowchart in the case of carrying out flow control increase / decrease control which increases / decreases a blood flow rate with respect to an interlocking blood flow rate.

<One Embodiment>
Hereinafter, a heart-lung machine (blood circulation system) according to an embodiment of the present invention will be described with reference to FIGS.
FIG. 1 is a circuit diagram illustrating a schematic configuration of a heart-lung machine according to an embodiment. FIG. 2 is a longitudinal sectional view illustrating a schematic configuration of a reservoir according to an embodiment, and FIG. 3 is a conceptual diagram illustrating attachment of a liquid level sensor to the reservoir. In the figure, reference numeral 100 denotes an oxygenator, reference numeral 102 denotes a reservoir, reference numeral 102S denotes a liquid level sensor (reservoir liquid level detection sensor), reference numeral 102T denotes an adhesive tape (reference liquid level setting means), and reference numeral 111 denotes a removal. Reference numeral 120 denotes a blood flow sensor, reference numeral 120 denotes a roller pump (blood pump), and reference numeral 140 denotes a control unit.

  As shown in FIG. 1, the oxygenator 100 includes, for example, a blood removal line 101, a reservoir 102, a liquid level sensor (reservoir liquid level detection sensor) 102S, an adhesive tape (reference liquid level setting means) 102T, Blood line 103, first blood supply line (blood supply line) 104, artificial lung 105, second blood supply line (blood supply line) 106, and blood removal rate sensor (blood removal rate measurement means) 111 A roller pump (blood feeding pump) 120, a blood removal regulator (flow rate adjusting means) 121, and a control unit 140.

  Further, the blood removal line 101, the reservoir 102, the blood line 103, the roller pump 120, the first blood supply line 104, the oxygenator 105, and the second blood supply line 106 are connected in this order, and the blood removal line 101 and the blood supply line 106 are connected. It can be connected to the patient (human body) P via the blood line 106.

  The removed blood is temporarily stored in the reservoir 102, and the patient is transferred by a roller pump (blood supply pump) 120 via the first blood supply line 104, the artificial lung 105, and the second blood supply line 106. Cycles to P.

One end of the blood removal line 101 can be connected to the patient P, and blood received from the vein is transferred to the reservoir 102.
Further, the blood removal line 101 is provided with a sensor or the like (not shown) for monitoring the blood concentration or oxygen concentration as necessary. Note that the above-described sensor or the like may be provided in the blood line 103 and the first blood supply line 104 instead of the blood removal line 101.

Moreover, the blood removal line 101 is comprised by the tube formed, for example with resin, such as polyvinyl chloride.
Further, the blood removal line 101 is provided with a blood removal regulator 121 and a blood removal volume sensor 111 in this order. The blood removal rate sensor 111 and the blood removal regulator 121 may be arranged in this order.

  As shown in FIG. 2, the reservoir 102 includes a reservoir body 102A, a head cap 102B attached to the upper portion of the reservoir body 102A, a partition plate 102C disposed inside the reservoir body 102A, and a filter 102F. Blood that has been removed from blood and sucked blood can be stored in the main body 102A.

The reservoir body 102A is configured to have a protruding portion that partially extends downward, and the first storage chamber Q1 and the second storage chamber Q2 are defined by the partition plate 102C and the filter 102F.
In addition, a liquid level scale 102G capable of visually observing blood stored in the reservoir 102 is displayed on the outer surface of the protruding portion of the reservoir body 102A.

  In addition, the reservoir body 102A has an inlet P1 into which blood flows into the upper part, and the inlet P1 is connected to the blood removal line 101, so that the blood removed from the blood through the blood removal line 101 is the first reservoir chamber. It flows into Q1.

  Further, the blood sucked into the reservoir main body 102A through the suction blood inlet P2 formed in the head cap 102B flows into the second storage chamber Q2 as necessary.

  The blood flowing into the second storage chamber Q2 is guided toward the filter 102F by the partition plate 102C, and the filter 102F filters the blood in the second storage chamber Q2 and moves to the first storage chamber Q1. ing.

  The first storage chamber Q1 temporarily stores the blood flowing in through the inflow port P1 and the blood flowing in through the filter 102F, and passes through the outflow port P3 formed at the lower end of the protruding portion of the reservoir body 102A. Thus, blood flows out to the blood line 103.

The liquid level sensor (reservoir liquid level detection sensor) 102S is constituted by, for example, a capacitance type sensor that can detect blood stored in the reservoir body 102A by capacitance.
As shown in FIG. 3, the liquid level sensor 102S is attached to an arbitrary position on the outer surface of the reservoir 102 by an adhesive tape (reference liquid level setting means) 102T and detects the liquid level in the reservoir 102. ing.

Then, the operator moves the liquid level sensor 102S along the liquid level scale 102G within the range between the upper limit liquid level H at which overflow does not occur and the lower limit liquid level L at which erroneous air feeding does not occur, and sets the reference liquid level P0. It has become.
The reservoir 102 is provided with a lower limit position detection sensor (not shown) for detecting the lower limit liquid level L.

  The blood line 103 has the same configuration as the blood removal line 101, and transfers blood received from the reservoir 102 to the roller pump 120.

  The roller pump 120 includes, for example, a rotating roller and a tube formed of a flexible resin that is disposed outside the rotating roller, and the rotating roller rotates to squeeze the tube and suck blood out. Thus, the blood stored in the reservoir 102 is sucked through the blood line 103, and the blood is transferred to the oxygenator 105 through the first blood supply line 104.

  Further, the roller pump 120 controls the number of rotations of the rotation roller by the rotation control signal output from the control unit 140, and sucks and feeds an amount of blood corresponding to the number of rotations of the rotation roller.

  The first blood supply line 104 has the same configuration as that of the blood removal line 101, and transfers blood sent from the roller pump 120 to the oxygenator 105.

The artificial lung 105 includes, for example, a hollow fiber membrane or a flat membrane having excellent gas permeability, and is configured to discharge carbon dioxide in blood and add oxygen.
The oxygenator 105 is integrally formed with a heat exchanger for adjusting the temperature of blood, for example.

The second blood supply line 106 receives blood from the artificial lung 105 by discharging carbon dioxide and adding oxygen, and transfers the blood to the artery of the patient P.
The second blood supply line 106 is provided with a filter (not shown) for removing foreign substances in the blood such as thrombus and bubbles.
Further, the second blood supply line 106 has the same configuration as the blood removal line 101.

  The blood removal regulator 121 is provided in the blood removal line 101, and includes, for example, a clamper 121A including a pair of clamp members, a servo motor (not shown) that operates the clamper 121A, and a blood removal regulator operation unit 121B. The operator manually operates the blood removal regulator operation unit 121B, and adjusts the clamp amount (clamping amount) of the clamper 121A by a servo motor, thereby changing the cross-sectional area of the blood removal line 101 to remove the blood removal line 101. It is configured to adjust the amount of blood removal flowing through.

  The blood removal rate sensor (blood removal rate measurement means) 111 is provided in the blood removal line 101 and uses, for example, an ultrasonic sensor that measures the flow velocity of blood using ultrasonic waves. Is sent to the control unit 140.

Next, a schematic configuration of the control unit 140 will be described with reference to FIG.
FIG. 4 is a block diagram illustrating a schematic configuration of the control unit 140 according to an embodiment.
The control unit 140 can perform linked blood supply control and blood flow increase / decrease control for supplying the blood flow rate of the roller pump 120 within a specific range with respect to the blood removal rate.

  Blood flow rate increase / decrease control is started by activating a blood flow rate increase / decrease control activation switch (not shown), and when the liquid level in the reservoir 102 is lower than the reference liquid level, the blood flow rate is decreased relative to the interlocked blood flow rate. When the liquid level in the reservoir 102 is higher than the reference liquid level, the blood flow rate is increased with respect to the interlocking blood flow rate. Then, after the reservoir liquid level reaches the reference liquid level, the blood flow increase / decrease control is terminated and the linked blood supply control is performed.

  The control unit 140 includes, for example, a blood removal flow signal reception unit 141, a blood removal flow calculation unit 142, a roller pump blood flow calculation unit 143, a roller pump control amount calculation unit 144, a roller pump control unit 145, A reservoir liquid level signal receiving unit 151 and a reservoir liquid level calculating unit 152 are provided.

The control unit 140 is connected to the blood removal rate sensor 111, the liquid level sensor 102S, and the roller pump 120 by a cable.
The blood removal amount signal receiving unit 141 is connected to the blood removal amount sensor 111 and receives a blood removal amount signal sent from the blood removal amount sensor 111.

  The blood removal amount calculation unit 142 is configured to calculate the blood removal amount based on the signal sent from the blood removal amount signal reception unit 141. Specifically, for example, the blood removal rate can be calculated from the product of the blood removal flow rate calculated from the blood removal flow rate signal and the flow area of the blood removal line 101.

  The reservoir liquid level signal reception unit 151 receives reservoir liquid level detection data sent from the liquid level sensor 102S.

  The reservoir liquid level calculation unit 152 determines that the reservoir liquid level has reached the reference liquid level based on the reservoir liquid level signal received from the reservoir liquid level signal reception unit 151 (for example, the presence or absence of blood at the position of the liquid level sensor 102S). Whether or not the reservoir liquid level is located above or below the reference liquid level is determined.

The roller pump blood flow rate calculation unit 143 calculates, for example, an interlocked blood flow rate that is linked to the blood removal rate, based on the blood removal rate received from the blood removal rate calculation unit 142.
In this embodiment, the blood flow rate of the roller pump 120 is configured to perform synchronous control, which is an aspect of interlocking control that controls the blood flow rate within a specific range with respect to the blood flow loss. .

In addition, the roller pump control amount calculation unit 143 is based on the reservoir liquid level calculation data sent from the reservoir adjustment amount calculation unit 152 when an activation signal is input from a blood supply increase / decrease control activation switch (not shown). A roller pump blood flow rate in the blood flow rate increase / decrease control is calculated. For example, when the reservoir liquid level is higher than the reference liquid level, the blood flow rate is increased by 20% with respect to the interlocked blood flow rate, and when the reservoir liquid level is lower than the reference liquid level, the blood flow rate is increased. It is calculated by reducing 20% with respect to the interlocking blood flow.
In addition, the increase / decrease blood flow when performing the increase / decrease control of the blood flow may be arbitrarily set from an increase / decrease setting input unit (not shown), for example.

  The roller pump control amount calculation unit 143 is configured to send the blood flow rate in the interlocked blood flow control or the blood flow rate increase / decrease control to the roller pump control amount calculation unit 144 as roller pump blood flow rate data.

  Based on the roller pump blood flow data received from the roller pump blood flow rate calculation unit 143, the roller pump control amount calculation unit 144 is, for example, data indicating the flow characteristics of the blood flow rate and the blood rotation speed of the roller pump 120. The roller pump control amount (rotation speed) is calculated using a table or a calculation formula indicating the relationship between the blood flow rate of the roller pump 120 and the blood supply rotation speed.

  The roller pump control unit 145 outputs a signal corresponding to the roller pump control amount (rotation speed) received from the roller pump control amount calculation unit 144 to the roller pump 120.

Next, with reference to FIG. 5, the operation | movement procedure in the case of carrying out the interlocking control of the blood flow rate with respect to the blood removal rate in the oxygenator 100 which concerns on one Embodiment is demonstrated. FIG. 5 is a diagram illustrating an operation procedure of the heart-lung machine according to the embodiment, and is a flowchart in the case of interlocking blood supply control in which the blood flow rate is interlocked with the blood removal rate.
(1) First, a blood removal amount signal is received (S11).
(2) Next, the blood removal amount is calculated based on the received blood removal amount signal (S12).
(3) Next, based on the calculated blood removal volume, a roller pump blood flow volume linked to the blood removal volume is calculated (S13).
(4) Next, the roller pump control amount (rotation speed) is calculated by referring to the roller pump blood flow rate to the blood flow rate characteristic (S14).
(5) Next, a signal corresponding to the roller pump control amount is output to the roller pump 120 (S15). When S15 is executed, the process proceeds to S11.
The above steps S11 to S15 are repeatedly executed at a predetermined cycle until, for example, the operation is completed and the blood circulation is completed.

Next, with reference to FIG. 6, an operation procedure in the case of the blood flow increase / decrease control based on the detection result of the liquid level sensor in the oxygenator 100 according to the embodiment will be described. FIG. 6 is a diagram for explaining an operation procedure of the heart-lung machine according to one embodiment, and is a flowchart in the case of controlling blood flow increase / decrease.
The flow chart shown in FIG. 6 is for a case where an instruction to increase / decrease blood flow control is given by a blood supply increase / decrease control activation switch (not shown). It is assumed that blood does not flow from other than blood line 101.

(1) First, a reservoir liquid level signal is received (S21).
(2) Next, based on the reservoir liquid level signal, it is determined whether the reservoir liquid level is located above or below the reference liquid level (S22).
(3) Next, a blood removal amount signal is received (S23).
(4) Next, the blood removal amount is calculated based on the received blood removal amount signal (S24).
(5) Next, based on the reservoir liquid level calculated in S22, when the reservoir liquid level is above the reference liquid level, the blood flow rate is increased with respect to the interlocked blood flow rate, and the reservoir liquid level is When it is below the liquid level, the blood flow rate is decreased with respect to the interlocking blood flow rate, and the roller pump blood flow rate in the blood flow rate increase / decrease control is calculated. (S25).
(6) Next, the roller pump control amount (number of rotations) is calculated with reference to the roller pump blood flow rate with reference to the blood flow rate characteristic (S26).
(7) Next, a signal corresponding to the roller pump control amount is output to the roller pump 120 (S27).
(8) Next, it is determined whether or not the reservoir liquid level has reached the reference liquid level (S28).
When the reservoir liquid level reaches the reference liquid level (S28: Yes), the flowchart ends and normal interlocking control is started. When the reservoir liquid level does not reach the reference liquid level (S28: No), S23 is started. Migrate to

According to the heart-lung machine 100 according to the embodiment, the control unit 140 controls the blood flow of the blood pump 120 in conjunction with the blood removal rate, and controls the blood flow, and the liquid level of the reservoir 102 is the reference liquid level. When it is lower than P0, the blood flow rate of the blood pump 120 is decreased, and when the liquid level in the reservoir 102 is higher than the reference liquid level P0, the blood flow rate of the blood pump is increased. The blood flow rate to be sent to the patient P can be adjusted.
Further, since the reference liquid level P0 of the reservoir 102 can be arbitrarily set by the adhesive tape (reference liquid level setting means) 102T, the operator can efficiently set the reference liquid level P0.
As a result, when it is necessary to increase or decrease the blood flow rate depending on the situation during the operation, the blood can be circulated efficiently and stably.

  Further, according to the heart-lung machine 100 according to the embodiment, the control unit 140 controls blood flow increase / decrease until the liquid level of the reservoir 102 reaches the reference liquid level. When the liquid level 102 returns to the reference position P0, it is possible to automatically switch to the linked blood feeding control. Further, it is possible to prevent the liquid level in the reservoir 102 from being excessively lowered and prevent air from being erroneously sent, and to prevent the liquid level in the reservoir 102 from rising and overflowing.

In addition, this invention is not limited to the said embodiment, A various change is possible in the range which does not deviate from the meaning of invention.
For example, in the above embodiment, the case where the liquid level sensor 102S is configured by a capacitive liquid level sensor has been described. For example, an optical liquid level sensor that is attached to the outer surface of the reservoir 102 and detects the liquid level. Alternatively, an ultrasonic liquid level sensor may be applied, or a level sensor capable of detecting the liquid level continuously or at a plurality of positions may be applied.

  In the above embodiment, the case where the adhesive tape 102T to which the liquid level sensor 102S is attached is used as the reference liquid level setting means has been described. However, the adhesive tape 102T may be used as a fixing means for the liquid level sensor 102S. Whether or not the liquid level setting means is provided can be arbitrarily set. Further, a reference liquid level setting means (for example, a slide rail, a mounting screw, etc.) other than the adhesive tape 102T may be used, or a fixing means other than the adhesive tape 102T may be used.

  In the above embodiment, the case where the blood flow rate increase / decrease control is performed until the reservoir liquid level reaches the reference liquid level has been described. However, the end condition of the blood flow rate increase / decrease control can be arbitrarily set. It is good also as a structure which complete | finishes blood flow rate increase / decrease control, when there exists other than the reference | standard liquid level P0.

  Moreover, although the said embodiment demonstrated the case where the increase / decrease blood flow volume in blood flow rate increase / decrease control was increased / decreased with a fixed flow volume (for example, 20%) with respect to the interlocking blood flow volume, the increase / decrease transfer in blood flow volume increase / decrease control was demonstrated. The blood flow rate can be arbitrarily set. For example, the blood flow rate may be controlled to increase or decrease for a set time, or the blood flow rate may be increased or decreased based on a preset function or pattern.

  Moreover, in the said embodiment, although the case where the blood feeding pump was comprised with the roller pump 120 was demonstrated, it replaced with the roller pump 120 and may comprise with a centrifugal pump.

  Further, in the embodiment, the case where the blood removal regulator 121 is provided as the flow rate adjusting means has been described, but whether or not the blood removal regulator 121 is provided can be arbitrarily set.

  Further, in the embodiment, the case where an ultrasonic sensor is used as the blood flow removal sensor 111 has been described. However, in place of the ultrasonic sensor, various known flow measurement means using a laser, an infrared ray, or the like are used. Also good.

  Moreover, in one Embodiment, although an example of schematic structure of the flowchart which concerns on FIG. 5, FIG. 6 regarding the roller pump 120 was shown, it cannot be overemphasized that algorithms other than the said flowchart may be used.

  In the above embodiment, the case where the blood circulation system is applied to the heart-lung machine 100 has been described. However, the blood circulation system may be applied to a blood circulation system used in a surgical operation other than the heart-lung machine.

  According to the blood circulation system of the present invention, in a blood circulation system having a reservoir, blood circulation can be efficiently and stably performed when it is necessary to increase or decrease the blood flow rate depending on the situation during the operation. So it is industrially available.

P Patient (human body)
100 Cardiopulmonary apparatus (blood circulation system)
101 Blood removal line 102 Reservoir 102S Liquid level sensor (Reservoir liquid level detection sensor)
102G Liquid level scale 102T Adhesive tape (reference liquid level setting means)
104 First blood supply line (blood supply line)
105 Artificial lung 106 Second blood supply line (blood supply line)
111 Blood removal sensor (blood removal measurement means)
120 Roller pump (blood pump)
121 Blood removal regulator (flow rate adjustment means)
140 Control unit

Claims (3)

A blood circulation system that is connectable to a human body and sends blood that has been removed to a human body using a blood pump.
A reservoir for temporarily storing the removed blood;
A reservoir liquid level detection sensor for detecting the liquid level of the reservoir;
A blood removal line for transferring the blood that has been removed to the reservoir;
A blood removal measuring means for measuring blood removal provided in the blood removal line;
A blood supply line for transferring blood from the reservoir to the human body;
A blood pump for delivering blood via the blood line;
A control unit for controlling the blood flow of the blood pump in conjunction with the blood removal rate within a specific range;
With
The controller is
When the liquid level of the reservoir is lower than the reference liquid level, the blood flow rate of the blood pump is decreased,
A blood circulation system configured to increase a blood flow rate of the blood pump when the liquid level of the reservoir is higher than the reference liquid level. The blood circulation system according to claim 1,
A blood circulation system comprising reference liquid level setting means for adjusting the reference liquid level detected by the reservoir liquid level detection sensor. The blood circulation system according to claim 1 or 2,
The controller is
A blood circulation system configured to increase / decrease a blood flow rate of the blood pump until the liquid level of the reservoir reaches the reference liquid level.

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