JP2018070567A - Liquid bait agent for pest control - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a liquid bait agent for pest control that has sufficient attraction to make pests eat it, and has excellent liquid storage stability.SOLUTION: A liquid bait agent for pest control contains an insecticidal component (A), fatty acid triglyceride (B), a nonionic surfactant (C) and water (D). The content of (C) component is, preferably, 1-10 mass% relative to the total mass of the liquid bait agent for pest control. The mass of (B) component and the mass of (C) component preferably satisfy the relationship of the formula (1): [the mass of (C) component]/[the mass of (B) component]=1-50.SELECTED DRAWING: None

Description

  The present invention relates to a liquid bait for controlling pests.

Conventionally, a bait agent for controlling pests has been used from the viewpoint of ease of manufacture and ease of handling.
However, in an environment where there is water or food around the bait agent, there is a problem that the insect pest is difficult to eat the solid bait agent and the insect pest control effect is not sufficiently exhibited.

  Then, the eating property of a pest is improved by making a bait agent into a liquid or a gel form (patent document 1, patent document 2). In the present specification, the pest eating property refers to the amount of the pest that eats the bait agent, and the more the pest eats the bait agent, the better the eating property.

JP 2002-316901 A JP 2007-99704 A

However, in the technique of Patent Document 1, an organic solvent is used to dissolve the insecticidal component, resulting in a decrease in the eating habits of the pests.
Moreover, although the technique of patent document 2 is aiming at the improvement of the eating property of a pest by using water as a solvent, it is easy to deposit an insoluble insecticidal component in water, and there exists a problem in the storage stability of a liquid. . In the present specification, the storage stability of a liquid refers to the degree of change in the state of appearance when a liquid bait agent is allowed to stand under a predetermined condition, and the amount of solids deposited in the liquid is small. The storage stability of the liquid is better.
Accordingly, an object of the present invention is to provide a liquid bait agent for controlling pests that has good pest eating properties and good liquid storage stability.

The present invention has the following aspects.
[1] A liquid bait agent for controlling pests containing an insecticidal component (A), a fatty acid triglyceride (B), a nonionic surfactant (C) and water (D).
[2] The liquid bait agent for pest control according to [1], wherein the content of the component (C) is 1 to 10% by mass relative to the total mass of the liquid bait agent for pest control.
[3] The liquid bait for pest control according to [1] or [2], wherein the mass of the component (B) and the mass of the component (C) satisfy the relationship of the following formula (1).
[Mass of component (C)] / [Mass of component (B)] = 1 to 50 (1)
[4] The pest control liquid bait according to any one of [1] to [3], wherein the component (A) is a non-pyrethroid insecticidal component.
[5] The component (C) is polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbite fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene hydrogenated castor oil fatty acid ester The liquid bait agent for pest control according to any one of [1] to [4], which is one or more selected from the group consisting of:
[6] The liquid bait for pest control according to any one of [1] to [5], which is for cockroaches.

  The liquid bait agent for pest control according to the present invention has good pest eating property and good liquid storage stability.

It is the perspective view which showed an example of the insect pest control apparatus which accommodates the liquid bait agent for insect pest control of this invention.

(Liquid bait for pest control)
The liquid bait agent for pest control according to the present invention (hereinafter sometimes simply referred to as “bait agent”) comprises (A) component, (B) component, (C) component, and (D) component. Contains and is liquid at room temperature.
The normal temperature here means 15 ° C. to 25 ° C. (17th revised Japanese Pharmacopoeia General Rules 16).

The liquid bait for controlling pests of the present invention is an oil-in-water (O / W) emulsion that is milky or clear in appearance at room temperature. From the viewpoint of storage stability of the liquid, the particle diameter of the emulsified droplets is preferably 1 μm or less, more preferably 100 nm or less, and particularly preferably 50 nm or less. When the particle diameter of the emulsified droplets is 1 μm or less, the appearance may be clear, and the emulsion stability is high without changing the appearance even after long-term storage.
The particle diameter can be measured by, for example, dynamic light scattering (DLS) using Zetasizer Nano-ZS (MALVERN).

The pH range of the liquid bait for controlling pests is preferably 3 or more, 7 or less, more preferably 3 or more and 6.5 or less, and even more preferably 3.5 or more and 6 or less. When the pH range is within the above range, the stability and antiseptic properties of the bait agent are good.
For example, the pH can be expressed by a value shown after 1 minute has elapsed by directly immersing the glass electrode in a pest control bait agent using a glass electrode type pH meter (manufactured by Toa DKK Co., Ltd., “HM-30R”). .

  The viscosity of the liquid bait for controlling insect pests is preferably 0.6 to 10 mPa · s, more preferably 0.8 to 8 mPa · s at 25 ° C. When the viscosity is within the above range, it is easy to obtain effects such as fast-acting properties, eating properties, and adhesion as a liquid preparation.

<(A) component>
The component (A) is an insecticidal component. By containing (A) component, the pest which ate the liquid bait agent for pest control can be killed, and a pest control effect can be exhibited.
(A) A component will not be specifically limited if it is an insecticidal component used with a pharmaceutical, a quasi-drug, an agricultural chemical, miscellaneous goods, etc. As the component (A), fipronil, propoxur, methoxadiazone, amidoflumet, hydramethylnon, and the like, which are non-pyrethroid insecticides, are preferable because pests have good eating properties. From the viewpoint of pest control effect, fipronil is particularly preferable.
In addition, when a pyrethroid type insecticidal component is used, a pest may repel the liquid bait agent for pest control by long-term use, and a pest control effect may fall.

  Many (A) components are poorly water-soluble. The poor solubility in water means that the solubility in water at 20 ± 5 ° C. is less than 0.1% by mass.

The content of the component (A) is appropriately selected depending on the type of the component (A), but in order to obtain a sufficient pest control effect, the content is 0.0005 to the total mass of the liquid bait agent for pest control. 2 mass% is preferable and 0.01-1 mass% is more preferable.
When the content of the component (A) is 0.0005% by mass or more with respect to the total mass of the liquid bait agent for pest control, a better pest control effect can be obtained, and a better liquid is obtained at 2% by mass or less. Storage stability can be maintained.

<(B) component>
The component (B) is a fatty acid triglyceride. By containing the component (B), the precipitation of the component (A) can be suppressed and the eating property of the pest can be improved.
The component (B) is not particularly limited as long as it is a fatty acid triglyceride used in pharmaceuticals, quasi drugs, cosmetics, agricultural chemicals, miscellaneous goods and the like. From the viewpoint of improving the eating property of pests, vegetable oils containing unsaturated fatty acids such as oleic acid, linoleic acid, and linolenic acid are preferred. For example, medium-chain fatty acid triglycerides, olive oil, persic oil, apricot oil, kukui nut oil, safflower oil, almond oil, corn oil, sunflower oil, jojoba oil, sesame oil, macadamia nut oil, coconut oil, rosehip oil, avocado oil Etc.

(B) 0.05-3 mass% is preferable with respect to the total mass of the liquid bait agent for insect pest control, as for content of (B) component, 0.1-2 mass% is more preferable, 0.2-1 mass% Is more preferable.
Precipitation of the component (A) during storage can be suppressed more favorably at 0.05% by mass or more, and separation of a liquid bait agent for controlling pests can be better inhibited at 3% by mass or less.

<(C) component>
Component (C) is a nonionic surfactant. By containing the component (C), the solubility of the components (A) and (B) in water (storage stability of the liquid) is improved.
The component (C) is not particularly limited as long as it is a nonionic surfactant used in pharmaceuticals, quasi drugs, cosmetics, agricultural chemicals, miscellaneous goods and the like.
Examples of the component (C) include polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbite fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene hydrogenated castor oil fatty acid ester, Examples thereof include glycerin fatty acid ester, sorbitan fatty acid ester, and polyoxyethylene sorbitan fatty acid ester.
Examples of the polyoxyethylene hydrogenated castor oil include polyoxyethylene (20) hydrogenated castor oil, polyoxyethylene (30) hydrogenated castor oil, polyoxyethylene (40) hydrogenated castor oil, and polyoxyethylene (50) hydrogenated castor oil. , Polyoxyethylene (60) hydrogenated castor oil, polyoxyethylene (80) hydrogenated castor oil, and the like.
Examples of the polyoxyethylene sorbite fatty acid ester include tetraoleic acid polyoxyethylene (40) sorbit, tetraoleic acid polyoxyethylene (60) sorbit, and the like.
Examples of the polyoxyethylene alkyl ether include polyoxyethylene lauryl ether and polyoxyethylene oleyl ether.
Examples of the polyoxyethylene glycerin fatty acid ester include polyoxyethylene glyceryl monolaurate, glyceryl polyoxyethylene oleate, and the like.
Examples of the polyglycerol fatty acid ester include polyglyceryl monolaurate, polyglyceryl monostearate, polyglyceryl monomyristate, and the like.
Examples of the polyoxyethylene hydrogenated castor oil fatty acid ester include polyoxyethylene hydrogenated castor oil laurate, polyoxyethylene hydrogenated castor oil isostearate, and the like.
Examples of the glycerin fatty acid ester include glyceryl monolaurate.
Examples of sorbitan fatty acid esters include coconut fatty acid sorbitan, sorbitan monolaurate, sorbitan monooleate, and the like.
Examples of the polyoxyethylene sorbitan fatty acid ester include polyoxyethylene (20) coconut oil fatty acid sorbitan, polyoxyethylene (20) sorbitan monolaurate, polyoxyethylene (20) sorbitan monooleate, and the like.
In the above compounds, the numerical value in () represents the average number of moles of ethylene oxide added.

  The component (C) is selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbite fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, polyoxyethylene hydrogenated castor oil fatty acid ester 1 If it is at least a seed, the liquid stability becomes better, which is preferable.

  (C) As for the HLB (Hydrophyl Lipophile Balance) value of a component, 11-15 are preferable. When the HLB value is 11 or more, it is possible to suppress a decrease in the appearance stability of the liquid bait for controlling pests. The HLB value is 15 or less, and the precipitation of the component (A) during storage can be suppressed. Here, the HLB value is a numerical value of 0 to 20 that represents the balance between hydrophobicity and hydrophilicity. The closer to 0, the less soluble in water, and the closer to 20, the easier it is to dissolve in water.

(C) As for content of a component, 1-10 mass% is preferable with respect to the total mass of the liquid bait agent for pest control, and 3-6 mass% is more preferable.
The storage stability of the liquids of the component (A) and the component (B) can be improved at 1% by mass or more, and a decrease in eating habits can be suppressed at 10% by mass or less.

It is preferable that the mass of (B) component and the mass of (C) component satisfy | fill the relationship of following formula (1).
[Mass of component (C)] / [Mass of component (B)] = 1 to 50 (1)
The left side of the formula (1) represents the ratio of the mass of the component (C) to the mass of the component (B), preferably 1 to 50, more preferably 5 to 30, and still more preferably 7 to 20.
When the ratio of the mass of the component (C) to the mass of the component (B) is 1 or more, the storage stability of the liquid bait for controlling pests can be improved. When it is 50 or less, a good pest control effect can be obtained with stability.

<(D) component>
The component (D) is water. (D) By containing a component, the liquid bait agent for pest control of this invention becomes liquid at normal temperature, and a favorable eating property is obtained rather than the conventional solid bait agent.
The component (D) is not particularly limited as long as it is water used in pharmaceuticals, quasi drugs, cosmetics, agricultural chemicals, miscellaneous goods, and the like.

  (D) 45 mass%-80 mass% are preferable with respect to the total mass of the liquid bait agent for pest control, and, as for content of a component, 50 mass%-75 mass% are more preferable. When the content is 45% by mass or more, better eating property can be obtained. Storage stability is good at 75% by mass or less.

<Optional component>
The liquid bait for controlling insect pests of the present invention can be blended with additives normally used in insecticides as additives, as long as the effects of the present invention are not impaired. Specifically, preservatives, pH adjusters, anticorrosive agents, wetting agents, excipients and the like can be blended.

Examples of preservatives include methyl paraoxybenzoate, ethyl paraoxybenzoate, propyl paraoxybenzoate, butyl paraoxybenzoate, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, cetylpyridinium chloride, benzalkonium chloride, thiabendazole, And proxel.
Examples of the pH adjuster include citric acid, sodium citrate, sodium hydroxide, phosphoric acid, sodium dihydrogen phosphate, triisopropanolamine, triethanolamine and the like.
Examples of the accidental food preventive agent include red pepper extract and denatonium benzoate.
Examples of the wetting agent include polyhydric alcohols such as propylene glycol, dipropylene glycol, glycerin, and sorbitol. By containing a polyhydric alcohol, it becomes easy to produce a liquid bait agent, and the liquid supply property and wettability to the impregnated body may be improved. The content of the polyhydric alcohol is preferably 5% by mass to 20% by mass and more preferably 8% by mass to 15% by mass with respect to the total mass of the liquid bait agent for pest control. When the content is 5% by mass or more, better wettability can be obtained. The eating property is good at 20% by mass or less. Moreover, 1-20 are preferable, as for the mass ratio (water / polyhydric alcohol) of water and a polyhydric alcohol, 2-15 are more preferable, and 5-12 are still more preferable.
Examples of excipients include syrup, fructose, and sucrose.

In addition, the sum total of (A) component-(D) component and arbitrary components does not exceed 100 mass%.

(Production method)
The manufacturing method of the liquid bait agent for pest control of this invention is not specifically limited, A well-known manufacturing method is employable. For example, the components (A) to (C) and the wetting agent are heated and dissolved at 80 ° C. to obtain an oil phase, the component (D) and optional components to be used as necessary are similarly heated to obtain an aqueous phase, Examples include a method of adding a water phase to the oil phase and stirring to obtain a pest control bait agent. Moreover, the liquid mixture which mixed (D) component and (C) component is heated, (A) component, (B) component and the arbitrary component used as needed are added, it stirs and it is for pest control. It may be a method for obtaining a liquid bait.

The liquid bait for controlling pests according to the present invention described above is a combination of the components (A) to (D), so that the pest eating property is high and the insecticidal effect is sufficiently obtained, and the liquid is stored stably. Excellent in properties. One of the factors for obtaining such an effect is that the combination of the component (B) and the component (C) suppresses the precipitation of the component (A), the appearance is clear, and the storage stability of the liquid is good. A liquid bait agent for pest control is obtained. Thereby, since content of (C) component may be small, the eating of the bait agent by a pest is not inhibited.
In addition, since the liquid bait for controlling insect pests of the present invention is a liquid preparation, it is advantageous in that it has superior quick-acting properties, high eating property, and spreadability of insecticidal effects due to high adhesion. .

(how to use)
Examples of the method of use include a method in which the pest control apparatus according to the present invention is accommodated in a pest control apparatus including an impregnated body, and the pest control apparatus is installed in a place where the target pest is active.
Specifically, there is a pest control apparatus 2 as shown in FIG. The pest control apparatus 2 includes an impregnated body 10, a bottle 42 containing the liquid bait L for pest control according to the present invention (hereinafter referred to as “liquid bait L”), and the liquid bait L in the bottle 42. A cap 44 for sealing the spout and a base 50 for supporting the bottle 42 in an inverted state are provided.

The impregnated body 10 is a medium that holds the liquid bait L supplied from the bottle 42.
The impregnated body is not particularly limited, and for example, a material formed of glass fiber, nonwoven fabric, resin fiber, pulp, or the like, or a foam molded body such as urethane foam can be used.
The pedestal 50 includes a bottom surface portion 52 having a rectangular shape in plan view, a protrusion 54 rising from the center portion of the bottom surface portion 52, a peripheral wall rising from the periphery of the bottom surface portion 52, and a support portion 56 that supports the bottle 42. It has. The support portion 56 is formed with four entrances 58 each having an opening having a rectangular shape in front view so as to be positioned at the center of each side of the bottom surface portion 52.
The impregnated body 10 is provided so that the protrusions 54 penetrate from the bottom to the top of the impregnated body 10.

In the pest control apparatus 2, the bottle 42 is supported by the upper end portion of the support portion 56 coming into contact with the shoulder portion 46 of the bottle 42 while the bottle 42 is mounted on the pedestal 50 in an inverted state. Further, the protrusion 54 of the pedestal 50 penetrates and penetrates the sealing piece of the cap 44. Thereby, the liquid bait agent L in the bottle 42 flows into the protrusion 54 and is supplied to the impregnated body 10 through the slit.
Then, when a pest that has entered the pedestal 50 from the entrance 58 reaches the impregnated body 10 and eats the liquid bait agent L from the impregnated body 10, death occurs.
In addition, in the pest control apparatus 2, the bottle 42 may be mounted on the pedestal 50 in an upright state before use, and may be mounted on the pedestal 50 in an inverted state by turning the bottle 42 upside down during use.

  The liquid bait for controlling insect pests according to the present invention is particularly effective as a bait for cockroaches because the eating property does not deteriorate even in a difficult control environment where water and food are present in the vicinity.

Hereinafter, the present invention will be described in more detail using examples, but the present invention is not limited to these examples.
The raw materials used in this example are as shown in the following (used raw materials).

(Raw materials used)
<(A) component>
Metoxadiazone: “Elemic” (trade name), manufactured by Sumitomo Chemical Co., Ltd.
Propoxle: “Propoxle” manufactured by Sumisho Agro International Co., Ltd.
Fipronil: “Bakuda” (trade name) manufactured by Sumitomo Chemical Co., Ltd.
<(B) component>
Corn oil: “Corn germ oil” manufactured by Nikko Chemicals Co., Ltd.
Sesame Oil: “Japanese Pharmacopoeia Sesame Oil” manufactured by Kaneda Corporation.
Safflower oil: “Safflower oil” manufactured by Nikko Chemicals.
<(C) component>
Polyoxyethylene (60) hydrogenated castor oil: “HCO-60” (trade name) manufactured by Nikko Chemicals Co., Ltd.
Polyoxyethylene (30) hydrogenated castor oil: “HCO-30” (trade name) manufactured by Nikko Chemicals Co., Ltd.
Polyoxyethylene (10) oleyl ether: “BO-10V” (trade name) manufactured by Nikko Chemicals Co., Ltd.
Polyoxyethylene (15) glyceryl oleate: “TMGO-15” (trade name) manufactured by Nikko Chemicals Co., Ltd.
Polyglyceryl monooleate: “Decalyn1-OV” (trade name) manufactured by Nikko Chemicals Co., Ltd.
Lauric acid PEG-60 hydrogenated castor oil: “RWL-160” (trade name) manufactured by Nippon Emulsion Co., Ltd.
Tetraoleic acid polyoxyethylene (40) Sorbit: “GO-440V” (trade name) manufactured by Nikko Chemicals Co., Ltd.
<(D) component>
Water: “Purified water” manufactured by Kominato Pharmaceutical Co., Ltd.
<Optional component>
Dipropylene glycol: “DPG-RF” (trade name) manufactured by ADEKA Corporation.
Minamata: “Koroshi wrap H75C” (trade name) manufactured by Nippon Corn Starch Co., Ltd.
<Other ingredients>
Squalane: "refined olive squalane" manufactured by Nikko Chemicals.
Agar: “Kanten powder UP-37” manufactured by Ina Food Industry Co., Ltd.

<Evaluation method for pest eating habits>
The components (A), (B) and (C) were dissolved by heating at about 80 ° C. to obtain an oil phase. On the other hand, the component (D) and other components were heated and dissolved at about 75 ° C. to obtain an aqueous phase. While stirring the aqueous phase at about 80 ° C., the oil phase was gradually added to obtain a liquid bait agent for controlling pests that was a clear liquid at room temperature.
After placing 6 g of bait agent and solid bait in a 40 cm × 50 cm basic container, 20 male and female cockroaches were released, and the amount of food consumed 24 hours later was calculated from the change in weight relative to the control. In accordance with the following criteria, the eating property of pests was evaluated, and the eating amount of 100 mg or more (A to Δ) was judged to be good.
(Evaluation criteria)
A: Eating amount is 200 mg or more.
○: Eating amount 150 mg or more and less than 200 mg.
Δ: Eating amount 100 mg or more and less than 150 mg.
▲: Eating amount 50 mg or more and less than 100 mg.
X: Eating amount is less than 50 mg.

<Method for evaluating storage stability of liquid>
A liquid bait for controlling pests was obtained in the same manner as described in the evaluation method for pest eating habits.
A glass container was filled with 30 g of bait agent, and after 1 month at 50 ° C. and 2 weeks at 5 ° C., the appearance at room temperature was observed, and the storage stability of the liquid was evaluated according to the following criteria. ◎ and ○ were judged as good.
(Evaluation criteria)
A: The appearance is the same as before storage.
○: A very small amount of fine powder is observed when gazing.
Δ: Crystals are precipitated.
X: Crystals are clearly precipitated.
-: Phase separation.

[Examples 1 to 13]
In accordance with the blending amounts shown in Table 1, each component is weighed in a predetermined amount, and is sufficiently obtained by a stirrer (Shinto Chemical Co., Ltd. Three-One Motor BL-600) in the same manner as described in the method for evaluating the pest eating property. The liquid bait agent for pest control was obtained by stirring and mixing.

[Comparative Examples 1-5]
A liquid bait agent for pest control was obtained in the same manner as in Example 1 except that the composition was changed as shown in Table 2.

As shown in Table 1 and Table 2, the liquid bait agents for controlling insect pests of Examples 1 to 13 containing the components (A) to (D) were excellent in eating property and liquid storage stability.
On the other hand, in the bait agent of Comparative Example 1 that does not contain the component (B), the storage stability of the liquid was Δ to ×. In the bait preparation of Comparative Example 2 using a substitute for the component (B), Comparative Example 3 not including the component (C), and Comparative Example 4 not including the component (D), the oil phase and the aqueous phase are separated. The storage stability of the liquid was not evaluated. In the bait preparation of Comparative Example 4 and Comparative Example 5 in which the liquid was gelled by adding agar, the pest eating quality was x.

  Thus, it was found that the liquid bait agent for controlling pests of the present invention has good pest eating properties and good liquid storage stability.

2 Pest control device 10 Impregnated body 42 Bottle 44 Cap 46 Shoulder part 50 Base 52 Bottom part 54 Projection part 56 Support part 58 Entrance

Claims (6)

  A liquid bait agent for controlling pests containing an insecticidal component (A), a fatty acid triglyceride (B), a nonionic surfactant (C) and water (D).   The liquid bait agent for pest control according to claim 1, wherein the content of the component (C) is 1 to 10% by mass with respect to the total mass of the liquid bait agent for pest control. The liquid bait agent for pest control according to claim 1 or 2, wherein the mass of the component (B) and the mass of the component (C) satisfy the relationship of the following formula (1).
[Mass of component (C)] / [Mass of component (B)] = 1 to 50 (1)   The liquid bait agent for pest control according to any one of claims 1 to 3, wherein the component (A) is a non-pyrethroid insecticidal component.   The component (C) is selected from polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbite fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene glycerin fatty acid ester, polyglycerin fatty acid ester, and polyoxyethylene hydrogenated castor oil fatty acid ester. The liquid bait agent for pest control as described in any one of Claims 1-4 which is 1 or more types.   The liquid bait for pest control according to any one of claims 1 to 5, which is for cockroaches.

Images