JP2018030955A - Detergent composition and method for cleaning product manufacturing facility - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a detergent composition which has good cleanability, can simply perform rinse, and is suitable for cleaning a manufacturing facility in a manufacturing factory of a product using an oily component.SOLUTION: A detergent composition contains 0.1-6 mass% of a polyoxyalkylene alkyl ether type non-ionic surface active agent as component (A), 3-20 mass% of a polyoxyalkylene alkyl ether type non-ionic surface active agent having a different ethylene oxide addition molar number from that of the component (A) as component (B), 1-20 mass% of a Pluronic-type non-ionic surface active agent as component (C), 1-20 mass% of alkyl glucoside as component (D), and water as component (E).SELECTED DRAWING: None

Description

  The present invention relates to a cleaning composition used for cleaning product manufacturing equipment such as pharmaceuticals, foods, and cosmetics, and a method for cleaning product manufacturing equipment using the cleaning composition.

  In manufacturing plants for pharmaceuticals, foods, cosmetics, and the like, when switching to a different product, the production line is washed to prevent the components of the previous product from being mixed. In particular, in manufacturing plants for products containing oily components, the production lines are thoroughly cleaned using spraying, dipping, brushing, and water pressure with a cleaning solution in order to prevent oily components remaining in the product manufacturing line from entering the next product. There is a need to.

  Products such as anti-inflammatory analgesics, anti-pruritic anti-inflammatory drugs, skin moisturizers, athlete's foot drugs, insect repellent creams, skin moisturizing creams, foundations, and skin cleansing agents are manufactured using the same production line. In these products, oily components such as hydrocarbons, fatty acids, alcohols and esters are used. As a cleaning method for product manufacturing facilities, there is a method of spraying and rinsing a surfactant diluent onto a manufacturing line, but there is a problem that the cleaning effect is low and dirt remains. Further, in order to clean the manufacturing equipment in detail, it is necessary to disassemble the manufacturing equipment, and a cleaning agent that can be used without disassembling the manufacturing equipment on a daily basis is required.

  Conventionally, various cleaning compositions and cleaning methods for oily components contained in pharmaceuticals and cosmetics have been proposed. For example, a method of cleaning with propylene glycol or a propylene glycol aqueous solution (Patent Document 1), a dibasic acid alkyl ester, Oil-based cleaning removal agents (Patent Documents 2 and 3) containing propylene glycol fatty acid esters as active ingredients have been proposed.

JP 2001-279295 A Japanese Patent Laid-Open No. 2005-2179 JP 2006-182894 A

  However, the method described in Patent Document 1 for washing with propylene glycol or an aqueous solution thereof is intended to wash gelled hydrocarbons or petrolatum, and the detergency of other oily components was not sufficient. Furthermore, the oil-based cleaning and removing agent described in Patent Documents 2 and 3 needs to have a high concentration in order to maintain the cleaning property, and the rinsing properties of the cleaning agent are not considered. As described above, conventional cleaning agents still have problems in the cleaning power of oily components used in pharmaceuticals and cosmetics. In particular, due to the recent rise in consumer awareness of product quality, pharmaceutical and cosmetic manufacturing In factories, more sophisticated cleanliness management is required, and sufficient cleaning and rinsing is required.

  The present invention has been made to solve the above-described conventional problems, and an object of the present invention is to provide a cleaning agent that has good cleaning properties and can be simply rinsed even during rinsing and a cleaning method therefor.

That is, the present invention
(1) As a component (A), a nonionic surfactant represented by the following general formula (1) is 0.1% by mass or more and 6% by mass or less, and as a component (B), the following general formula (2) The nonionic surfactant represented is 3% by mass or more and 20% by mass or less, (C) component, pluronic type nonionic surfactant is 1% by mass or more and 20% by mass or less, and (D) component is alkyl. A detergent composition comprising 1% by mass or more and 20% by mass or less of glucoside, and water as component (E),
(Chemical formula 1)
R1-O- (EO) _m- (PO) _n- R2 (1)
(Wherein R1 is an aliphatic hydrocarbon group having 8 to 18 carbon atoms, R2 is a hydrogen atom or an aliphatic hydrocarbon group having 1 to 4 carbon atoms, EO is ethylene oxide, PO is propylene oxide, , M and n represent the average added mole number of EO and PO, respectively, m is 20 or more and 80 or less, and n is a number of 0 or more and 10 or less.)
(Chemical formula 2)
R3-O- (EO) _x- (PO) _y- R4 (2)
(In the formula, R3 is an aliphatic hydrocarbon group having 10 to 16 carbon atoms, R4 is a hydrogen atom or an aliphatic hydrocarbon group having 1 to 4 carbon atoms, EO is ethylene oxide, and PO is propylene oxide. , X and y represent the average added moles of EO and PO, respectively, x is 10 or more and less than 20, and y is 1 or more and 20 or less.)
(2) The detergent composition according to (1) above, wherein the alkyl glucoside of the component (D) has an alkyl group having 4 to 10 carbon atoms,
(3) Said (1) or (2) whose mass ratio of (A) component, (B) component, and (C) component is [(B) + (C)] / (A) = 2 or more and 20 or less ) Cleaning composition,
(4) The detergent composition according to any one of (1) to (3) above, further comprising a glycol solvent as component (F),
(5) A treatment liquid containing 0.01% by mass or more and 10% by mass or less of the cleaning composition according to any one of (1) to (4) above on the floor, wall, outer surface, and inner surface of the product manufacturing facility. Product manufacturing equipment cleaning method, characterized by
Is a summary.

  The cleaning composition of the present invention exhibits good detergency when applied to the inner surface, outer surface, floor, and wall of manufacturing equipment for pharmaceuticals and cosmetics production lines. In the case of manufactured products such as pharmaceuticals, cosmetic antiphlogistics, antiphlogistics, skin moisturizers, athlete's foot drugs, insect repellent creams, skin moisturizing creams, foundations and skin cleansing agents, oils, waxes, hydrocarbons, fatty acids A good cleaning effect can be obtained even for soils containing oily components such as alcohols, esters, and pharmaceutical oily raw material oily components. Furthermore, since it is defoaming during cleaning, it can be cleaned without problems even in the piping.

  In the present invention, the nonionic surfactant used as the component (A) is a compound represented by the general formula (1), and R1 in the general formula (1) is an aliphatic hydrocarbon group having 8 to 18 carbon atoms. , Ethylene oxide: EO average addition mole number: m is 20 or more and 80 or less, propylene oxide: PO average addition mole number: n is 0 or more and 10 or less, R2 is a hydrogen atom or C1 to C4 aliphatic carbonization Although it is a compound that is a hydrogen group, from the viewpoint of detergency, R1 preferably has 10 or more and 16 or less carbon atoms, m is 22 or more and 60 or less, n is 0 or more and 7 or less, and R2 is preferably a hydrogen atom. More preferably, R1 has 12 or more and 15 or less carbon atoms, m is 24 or more and 50 or less, n is 0 or more and 5 or less, and R2 is a hydrogen atom.

  On the other hand, the nonionic surfactant used as the component (B) is a compound represented by the general formula (2), and R3 in the general formula (2) is an aliphatic hydrocarbon group having 10 to 16 carbon atoms, ethylene oxide. : Average addition mole number of EO: x is 10 or more and less than 20, propylene oxide: average addition mole number of PO: y is 1 or more and 20 or less, R4 is a hydrogen atom or an aliphatic hydrocarbon group having 1 to 4 carbon atoms From the viewpoint of defoaming properties, R3 preferably has 12 or more and 16 or less carbon atoms, x is 12 or more and 18 or less, y is 5 or more and 15 or less, and R4 is a hydrogen atom. Is preferred.

  As a nonionic surfactant of component (A), a compound in which R2 is a hydrogen atom is further required to be an aliphatic alcohol having 8 to 18 carbon atoms in a hydrocarbon group and 20 to 80 mol of ethylene oxide. Can be obtained by adding 10 mol or less of propylene oxide. Examples of the aliphatic alcohol having 8 or more and 18 or less carbon atoms in the hydrocarbon group include saturated, unsaturated, linear, and branched alcohols, such as octanol, nonanol, decanol, undecyl alcohol, dodecyl alcohol, and tridecyl. Examples include primary alcohols or secondary alcohols such as alcohol, tetradecyl alcohol, pentadecyl alcohol, hexadecyl alcohol, heptadecyl alcohol, octadecyl alcohol, elaidyl alcohol, and octadecenyl alcohol. In the case of a compound in which propylene oxide is further added together with ethylene oxide, both of them may be added in a block form or randomly added. As the nonionic surfactant of component (A), for example, commercially available NAROACTY CL series (manufactured by Sanyo Chemical Industries), EmulanTO series (manufactured by BASF), nonion E series (manufactured by NOF Corporation), DSK NL series ( Daiichi Kogyo Seiyaku Co., Ltd.), Pelletex PC series (Miyoshi Oil & Fats Co., Ltd.) and the like. The nonionic surfactant (A) can be contained in the cleaning composition in an amount of 0.1% by mass to 6% by mass, preferably 0.7% by mass to 4% by mass. More preferably, it is at least 3% by mass. If it is less than 0.1% by mass, the detergency may be lowered, and if it exceeds 6% by mass, the defoaming property may be lowered.

  As a nonionic surfactant of component (B), 10 mol or more and less than 20 mol of ethylene oxide, 1 mol or more and 20 mol or less of propylene oxide are added to an aliphatic alcohol having 10 to 16 carbon atoms of a hydrocarbon group. Obtained. As the aliphatic alcohol, aliphatic alcohols having 10 to 16 carbon atoms of the hydrocarbon group are used among the same aliphatic alcohols used for the nonionic surfactant of component (A). Ethylene oxide and propylene oxide may be added in block form or randomly added. Examples of the nonionic surfactant of component (B) include commercially available pullulafic LF series (BASF), Adecanol B series (ADEKA), Neugen LF series (Daiichi Kogyo Seiyaku Co., Ltd.), and the like. The nonionic surfactant of component (B) can be contained in the cleaning composition in an amount of 3% by mass or more and 20% by mass or less, preferably 5% by mass or more and 12% by mass or less, preferably 6% by mass or more, 10 mass% or less is more preferable. If it is less than 3% by mass, the defoaming property may be lowered, and if it exceeds 20% by mass, the washing property and storage stability may be lowered.

  Examples of the component (C) pluronic nonionic surfactant include pluronic block polymers, tetronic block polymers, reverse pluronic block polymers, and reverse tetronic block polymers. These may be used alone or in combination of two or more. Among these, from the viewpoints of detergency, defoaming properties and storage stability, pluronic block polymers and reverse pluronic block polymers are preferable, and reverse pluronic block polymers are more preferable. From the viewpoint of defoaming properties and storage stability, it is preferable that 10 mol% or more and 30 mol% or less of oxyethylene groups are included in the total of oxyethylene groups and oxypropylene groups. (C) The component pluronic-type nonionic surfactant is contained in the cleaning composition in an amount of 1 to 20% by mass, preferably 3 to 12% by mass, More preferably, the content is 4% by mass or more and 10% by mass or less. If the proportion of the component (C) in the cleaning composition is less than 1% by mass, the storage stability may be reduced, and if it exceeds 20% by mass, the cleaning property and antifoaming property may be reduced.

  (D) As an alkyl glucoside of a component, the alkyl glucoside which has a C4-C10 hydrocarbon group is preferable. These may be used alone or in combination of two or more. Of these, hexyl glucoside and 2-ethylhexyl glucoside are more preferable from the viewpoint of antifoaming properties and storage stability. (D) Component alkyl glucoside is contained in the detergent composition in an amount of 1% by mass or more and 20% by mass or less, preferably 2% by mass or more and 12% by mass or less, and preferably 3% by mass or more. More preferably, it is contained in an amount of 10% by mass or less. If the proportion of the component (D) in the cleaning composition is less than 1% by mass, the storage stability may be reduced, and if it exceeds 20% by mass, the cleaning property and antifoaming property may be reduced.

  The water of component (E) is not particularly limited, and includes tap water, industrial water, reclaimed water, ion exchange water, RO water, distilled water, soft water, and the like.

  In the cleaning composition of the present invention, the mass ratio [(B) + (C)] / (A) of the components (A), (B), and (C) is 2 or more and 20 or less. The (A) component, the (B) component, and the (C) component are preferably blended, and the (A) component so that [(B) + (C)] / (A) is 3 or more and 15 or less. More preferably, the component (B) and the component (C) are blended, and more preferably 5 or more and 10 or less. When [(B) + (C)] / (A) is less than 2, the defoaming property may be lowered, and when it exceeds 20, the washing property and storage stability may be lowered.

  The cleaning composition of the present invention may further contain a glycol solvent as the component (F). Further, when the component (F) is blended, the cleaning property and storage stability can be improved. Examples of glycol solvents include propylene glycol, polyethylene glycol, glycerin, ethylene glycol, ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol mono Examples include propyl ether, diethylene glycol monobutyl ether, butylene glycol, hexylene glycol and the like. These may be used alone or in combination of two or more. Of these, propylene glycol, polyethylene glycol, and diethylene glycol monobutyl ether are preferable, and propylene glycol is more preferable from the viewpoints of detergency and storage stability. (F) When mix | blending the glycol-type solvent of a component, 1 mass% or more and 20 mass% or less are preferable, 2 mass% or more and 15 mass% or less are more preferable, and 3 mass% or more is preferable. 10 mass% or less is more preferable. When the proportion of the component (F) is less than 1% by mass, there is a possibility that the improvement of cleaning properties and storage stability may not be recognized, and when it exceeds 20% by mass, an effect commensurate with the blending amount cannot be obtained.

  The cleaning composition of the present invention may further contain a polymer dispersant as the component (G). Furthermore, when (G) component is mix | blended, scale adhesion prevention property can be improved. As the polymer dispersant, polyacrylic acid, polymethacrylic acid, polymaleic acid, polyitaconic acid, acrylic acid-methacrylic acid copolymer, acrylic acid-maleic acid copolymer, olefin-maleic acid copolymer, acrylic acid- Sulfonic acid copolymer, maleic anhydride-styrene copolymer, maleic anhydride-ethylene copolymer, maleic anhydride-vinyl acetate copolymer, maleic anhydride-acrylic acid ester copolymer, and salts thereof Can be used. These polymer dispersants may be used alone or in combination of two or more. From the viewpoints of scale adhesion prevention and storage stability, polyacrylic acid or its salt, polymaleic acid or its salt, acrylic acid-methacrylic acid copolymer, acrylic acid-maleic acid copolymer, olefin-maleic acid copolymer An acrylic acid-sulfonic acid copolymer is preferred. The polyacrylic acid preferably has a weight average molecular weight of 500 or more and 20,000 or less, and particularly preferably has a weight average molecular weight of 1,500 or more and 15,000 or less. (G) When mix | blending the polymer dispersing agent of a component, 0.1 mass% or more and 20 mass% or less are preferable, as for the ratio in a cleaning composition, 1 mass% or more and 15 mass% or less are more preferable, 2 More preferably, it is at least 10% by mass. When the proportion of the component (G) is less than 1% by mass, there is a possibility that the improvement of the cleaning property and the scale adhesion preventing property may not be recognized, and when it exceeds 20% by mass, the effect corresponding to the blending amount cannot be obtained.

  The cleaning composition of the present invention may further include an alkali compound, chlorine-based or oxygen-based bleach, organic salt, solubilizer, dye, preservative, disinfectant, antifoaming agent, corrosion inhibitor, if necessary. A natural extract etc. can be mix | blended.

  In the method for cleaning a product manufacturing facility of the present invention, a treatment liquid containing 0.01% by mass or more and 10% by mass or less of the cleaning composition is applied to an object to be cleaned such as a floor, a wall, an outer surface, and an inner surface of the product manufacturing facility. On the other hand, it is applied and cleaned by spraying or immersing the object to be cleaned in the treatment liquid. When the treatment composition is prepared by diluting the cleaning composition, it is desirable to use clean water such as tap water, ground water, ion exchange water as the water used for dilution.

  When cleaning the tank in the product manufacturing facility, the processing liquid is sprayed by a movement accompanied by rotation from an injection nozzle, a roller ball, a shower ball, or the like, and cleaning is performed so that the processing liquid uniformly contacts the inside. In the case of cleaning the inside of the pipe, the treatment liquid is flowed into the pipe, preferably at a flow rate of 0.5 m / sec or more and 4.0 m / sec or less, more preferably 1.0 m / sec or more, 3 Cleaning is performed by flowing the treatment liquid at a flow rate of 0.0 m / sec or less.

  The method for cleaning a product manufacturing facility of the present invention can be applied to CIP cleaning. For CIP cleaning: 1. water washing; 2. washing 5. rinse with water 6. sterilization, Washing is repeated by rinsing with water, but some steps are omitted, the order is changed, or the same steps are repeated depending on the composition of the processing liquid and the type and state of the dirt. Is.

  In the CIP cleaning, the cleaning step with the cleaning liquid is preferably performed for 1 to 120 minutes, preferably 5 to 40 minutes, and the rinsing step is preferably 1 to 60 minutes, and more preferably 5 to 15 minutes. The cleaning liquid used in the cleaning step is preferably 10 ° C. or higher and 90 ° C. or lower, but more preferably 15 ° C. or higher and 80 ° C. or lower. The rinse water is preferably clean water such as tap water, ground water, ion exchange water, and preferably used at a temperature of 10 ° C. or higher and 90 ° C. or lower, more preferably 15 ° C. or higher and 80 ° C. or lower.

  Examples of the material of the washable surface in the present invention include resins such as stainless steel, polyurethane, polyester, and polypropylene, glass, and earthenware. Stainless steel is preferred.

  The product manufacturing equipment for cleaning by the method of the present invention mainly includes product manufacturing lines of manufacturing plants for pharmaceuticals, foods, cosmetics, etc., but the cleaning method of the present invention particularly manufactures pharmaceuticals and cosmetics containing oily components. Suitable for line cleaning.

  EXAMPLES Hereinafter, although an Example and a comparative example demonstrate this invention concretely, this invention is not limited by these. Each component used for blending in Examples and Comparative Examples is shown below. The compounds used in the test are described below. In addition, the numerical value of the mixing | blending of the Example in a table | surface and a comparative example represents the mass% of a pure part.

(A) Component A-1: Polyoxyethylene (EO: 40 mol) Myristyl ether A-2: Polyoxyethylene (EO: 20 mol) Decyl ether A-3: Polyoxyalkylene (EO: 25 mol, PO: 3 Mol) tridecyl ether A-4: polyoxyalkylene (EO: 30 mol, PO: 3 mol) isodecyl ether A-5: polyoxyalkylene (EO: 38 mol, PO: 2 mol) lauryl ether A-6: Polyoxyalkylene (EO: 20 mol, PO: 8 mol) cetyl ether

(B) Component B-1: Polyoxyalkylene (EO: 15 mol, PO: 10 mol) Lauryl ether B-2: Polyoxyalkylene (EO: 12 mol, PO: 12 mol) Lauryl ether B-3: Polyoxy Alkylene (EO: 10 mol, PO: 20 mol) Isodecyl ether B-4: Polyoxyalkylene (EO: 18 mol, PO: 15 mol) Cetyl ether B-5: Polyoxyalkylene (EO: 10 mol, PO: 8 mol) Tridecyl ether B-6: Polyoxyalkylene (EO: 15 mol, PO: 5 mol) Myristyl ether B-7: Polyoxyalkylene (EO: 12 mol, PO: 16 mol) Myristyl ether B-8: Polyoxyalkylene (EO: 10 mol, PO: 12 mol) Lauryl ether

(C) Component C-1: Polyoxyethylene polyoxypropylene block polymer 1, the average addition mole number of reverse type oxyethylene group (EO) is 42, and the average addition mole number of oxypropylene group (PO) is 14. .
C-2: Polyoxyethylene polyoxypropylene block polymer 2, reverse type oxyethylene group (EO) has an average addition mole number of 43, and oxypropylene group (PO) has an average addition mole number of 6.
C-3: Polyoxyethylene polyoxypropylene block polymer 3, oxyethylene group (EO) average addition mole number is 3, oxypropylene group (PO) average addition mole number is 17.
C-4: Polyoxyethylene polyoxypropylene block polymer 4, oxyethylene group (EO) average addition mole number is 10, oxypropylene group (PO) average addition mole number is 30.

(D) Component D-1: Hexyl glucoside D-2: Octyl glucoside D-3: 2-ethylhexyl glucoside D-4: Butyl glucoside D-5: Alkyl (C8-10) glucoside: 8 to 10 carbon atoms Alkyl glucoside having a hydrocarbon group

(F) Component F-1: Propylene glycol F-2: Polyethylene glycol (weight average molecular weight 400)
F-3: Diethylene glycol monobutyl ether F-4: Hexylene glycol F-5: Triethylene glycol

(G) Component G-1: Sodium polyacrylate 1 (weight average molecular weight 4,500, trade name is ACUSOL 445NG (92% pure), manufactured by Rohm and Haas)
G-2: Sodium polyacrylate 2 (weight average molecular weight is 8,000, trade name is Socaran PA30CL granule (pure 45%), manufactured by BASF)
G-3: Sodium acrylic acid-maleic acid copolymer (weight average molecular weight 40,000, trade name is ACUSOL 505N (pure content 35%), manufactured by Rohm and Haas)
G-4: Acrylic acid-sulfonic acid copolymer sodium (weight average molecular weight is 5,000, trade name is AQUALIC GL386 (pure 50%), manufactured by Nippon Shokubai Co., Ltd.)
G-5: Sodium polymaleate (weight average molecular weight 500, trade name Belclene 200LA neutralized with sodium hydroxide, manufactured by BWA)

Examples 1-80, Comparative Examples 1-20
A cleaning composition was prepared based on the formulations shown in Tables 1-10. The test shown below was done using each cleaning composition. The results are shown in Tables 1-10.

* 1: Detergency test method:
A stainless steel panel (SUS304, 5 cm × 7 cm rectangle, thickness 1 mm) coated with 0.6 g of skin cream (Nivea cream, manufactured by Nivea Kao) was used as a test piece and the weight was measured. This test piece was immersed in 300 mL of a treatment solution prepared by diluting each cleaning composition to 3% by mass with 75 mg / L [German hardness 4.2 ° DH] hard water in terms of calcium carbonate, and kept at a constant temperature of 80 ° C. Was allowed to stand for 20 minutes, rinsed with ion exchange water, allowed to dry naturally, and then weighed. The washing rate was calculated from the change in weight of the test piece before and after washing, and was shown on the following scale.
Evaluation method:
The cleaning rate was calculated from the following formula from the panel weight of the test specimen before and after cleaning, and evaluated from the cleaning rate according to the following criteria.
Cleaning rate (%) =
{(Panel weight before cleaning-Panel weight after cleaning) / (Addition amount of dirt)} × 100
Evaluation criteria:
◎: Cleaning rate is 80% or more ○: Cleaning rate is 60% or more and less than 80% △: Cleaning rate is 40% or more and less than 60% ×: Cleaning rate is less than 40%, Δ, ○, ◎ are practical Judged as having

* 2: Defoaming test method:
40 mL of a treatment solution prepared by diluting each cleaning composition to 3% by mass with 75 mg / L [German hardness 4.2 ° DH] hard water in terms of calcium carbonate is placed in an Epton tube with a 100 mL glass stopper and placed in a water bath. The temperature was raised to 80 ° C. Then, shake vigorously up and down 10 times, and after standing still for 1 minute while maintaining at 80 ° C., the height of the treatment liquid phase and the height of foaming from the treatment liquid surface were measured and determined from the following formula: From the ratio of foam, foamability was evaluated according to the following criteria.
Foam ratio = (foam height after 1 minute) / (foam height after 1 minute + height of detergent aqueous solution phase)
Evaluation criteria:
A: The ratio of bubbles is less than 0.02.
○: The ratio of bubbles is 0.02 or more and less than 0.04.
(Triangle | delta): The ratio of a bubble is 0.04 or more and less than 0.08.
X: The ratio of foam is 0.08 or more,
And Δ, ○, and ◎ were determined to be practical.

* 3: Corrosion prevention test (metal: stainless steel)
In a 300 mL tall beaker, 250 mL of a treatment liquid prepared by diluting each cleaning composition to 3% by mass with hard water of 75 mg / L [German hardness 4.2 ° DH] in terms of calcium carbonate was prepared. Next, a weighed stainless steel panel (25 mm × 7.5 mm × 1 mm; approximately 14.2 g) is placed in each treatment solution, heated in an autoclave at 140 ° C. for 3 hours, the stainless steel panel is taken out, and warm water at 80 ° C. After rinsing by repeating dipping and pulling up 10 times, a stainless steel panel dried at 105 ° C. for 2 hours was used as an evaluation sample, and the appearance change before and after the treatment was visually evaluated.
<Evaluation criteria>
○: No change in appearance is observed.
X: Appearance change is seen.
−: Measurement was impossible, and ○ was determined to be practical.

* 4: Corrosion prevention test (packing: EPDM)
In a 300 mL tall beaker, 250 mL of a treatment liquid prepared by diluting each cleaning composition to 3% by mass with hard water of 75 mg / L [German hardness 4.2 ° DH] in terms of calcium carbonate was prepared. Next, a weighed EPDM sheet (25 mm × 5.0 mm × 2 mm; about 2.8 g) is placed in each treatment solution, heated in an autoclave at 140 ° C. for 3 hours, taken out of the EPDM sheet, and warm water at 80 ° C. Inside, after immersing and pulling up 10 times repeatedly, the EPDM sheet dried at 105 ° C. for 2 hours was used as an evaluation sample, and the appearance change before and after the treatment was visually evaluated.
<Evaluation criteria>
○: No change in appearance is observed.
X: Appearance change is seen.
-: Measurement not possible
And ○ was determined to be practical.

* 4: Storage stability test 100 g of each cleaning composition was placed in a transparent glass bottle and allowed to stand at −5 ° C. and 40 ° C. for 1 month, and then the appearance was observed and evaluated according to the following criteria.
<Evaluation criteria>
○: Separation and turbidity are not seen and stable.
Δ: There is no overall separation, but some turbidity is observed.
X: Separation or turbidity is observed.
And Δ and ○ were determined to be practical.

Claims (5)

As the component (A), the nonionic surfactant represented by the following general formula (1) is 0.1% by mass or more and 6% by mass or less.
As the component (B), the nonionic surfactant represented by the following general formula (2) is 3% by mass or more and 20% by mass or less.
(C) As a component, a pluronic type nonionic surfactant is 1 mass% or more and 20 mass% or less,
(D) As an ingredient, alkyl glucoside is 1 mass% or more and 20 mass% or less,
(E) As a component, water,
A cleaning composition comprising:
(Chemical formula 1)
R1-O- (EO) _m- (PO) _n- R2 (1)
(Wherein R1 is an aliphatic hydrocarbon group having 8 to 18 carbon atoms, R2 is a hydrogen atom or an aliphatic hydrocarbon group having 1 to 4 carbon atoms, EO is ethylene oxide, PO is propylene oxide, m And n represents the average added mole number of EO and PO, respectively, m is 20 or more and 80 or less, and n is a number of 0 or more and 10 or less.)
(Chemical formula 2)
R3-O- (EO) _x- (PO) _y- R4 (2)
(Wherein R3 is an aliphatic hydrocarbon group having 10 to 16 carbon atoms, R4 is a hydrogen atom or an aliphatic hydrocarbon group having 1 to 4 carbon atoms, EO is ethylene oxide, PO is propylene oxide, x And y represents the average added mole number of EO and PO, respectively, x is 10 or more and less than 20, and y is 1 or more and 20 or less.) The detergent composition according to claim 1, wherein the alkyl glucoside of the component (D) has 4 to 10 carbon atoms in the alkyl group. The cleaning composition according to claim 1 or 2, wherein the mass ratio of the component (A), the component (B), and the component (C) is [(B) + (C)] / (A) = 2 or more and 20 or less. object. The detergent composition according to any one of claims 1 to 3, further comprising a glycol solvent as the component (F). A treatment liquid containing the cleaning composition according to any one of claims 1 to 4 in an amount of 0.01% by mass to 10% by mass is applied to a floor, a wall, an outer surface, and an inner surface of a product manufacturing facility. A method for cleaning product manufacturing equipment.