JP2017517361A5 - - Google Patents
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- JP2017517361A5 JP2017517361A5 JP2017511572A JP2017511572A JP2017517361A5 JP 2017517361 A5 JP2017517361 A5 JP 2017517361A5 JP 2017511572 A JP2017511572 A JP 2017511572A JP 2017511572 A JP2017511572 A JP 2017511572A JP 2017517361 A5 JP2017517361 A5 JP 2017517361A5
- Authority
- JP
- Japan
- Prior art keywords
- gas
- therapeutic gas
- supply system
- therapeutic
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000007789 gas Substances 0.000 claims description 1809
- 230000001225 therapeutic effect Effects 0.000 claims description 869
- 238000002347 injection Methods 0.000 claims description 171
- 239000007924 injection Substances 0.000 claims description 171
- 238000012790 confirmation Methods 0.000 claims description 123
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 100
- 229910052760 oxygen Inorganic materials 0.000 claims description 100
- 239000001301 oxygen Substances 0.000 claims description 100
- 238000011282 treatment Methods 0.000 claims description 77
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 72
- 239000012530 fluid Substances 0.000 claims description 51
- 230000008878 coupling Effects 0.000 claims description 47
- 238000010168 coupling process Methods 0.000 claims description 47
- 238000005859 coupling reaction Methods 0.000 claims description 47
- 238000004891 communication Methods 0.000 claims description 37
- 238000004364 calculation method Methods 0.000 claims description 22
- 230000007704 transition Effects 0.000 claims description 9
- 230000000007 visual effect Effects 0.000 claims description 8
- 230000004044 response Effects 0.000 claims description 2
- 238000002560 therapeutic procedure Methods 0.000 claims description 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 304
- 238000000034 method Methods 0.000 description 110
- 238000001802 infusion Methods 0.000 description 63
- 238000012795 verification Methods 0.000 description 42
- 230000003434 inspiratory effect Effects 0.000 description 40
- 230000000241 respiratory effect Effects 0.000 description 34
- 238000010926 purge Methods 0.000 description 33
- 230000008569 process Effects 0.000 description 30
- 230000006870 function Effects 0.000 description 27
- 238000004868 gas analysis Methods 0.000 description 26
- 238000011144 upstream manufacturing Methods 0.000 description 17
- 238000010200 validation analysis Methods 0.000 description 17
- 230000002457 bidirectional effect Effects 0.000 description 14
- 230000008859 change Effects 0.000 description 13
- 238000005070 sampling Methods 0.000 description 11
- 239000000356 contaminant Substances 0.000 description 10
- 238000005259 measurement Methods 0.000 description 10
- 230000003197 catalytic effect Effects 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 238000012544 monitoring process Methods 0.000 description 8
- 238000012360 testing method Methods 0.000 description 8
- 230000001105 regulatory effect Effects 0.000 description 7
- 238000001514 detection method Methods 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- 238000004458 analytical method Methods 0.000 description 5
- 230000001143 conditioned effect Effects 0.000 description 5
- 230000007423 decrease Effects 0.000 description 5
- MGWGWNFMUOTEHG-UHFFFAOYSA-N 4-(3,5-dimethylphenyl)-1,3-thiazol-2-amine Chemical compound CC1=CC(C)=CC(C=2N=C(N)SC=2)=C1 MGWGWNFMUOTEHG-UHFFFAOYSA-N 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 238000012854 evaluation process Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- JCXJVPUVTGWSNB-UHFFFAOYSA-N nitrogen dioxide Inorganic materials O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 description 4
- 230000008439 repair process Effects 0.000 description 4
- 230000002441 reversible effect Effects 0.000 description 4
- 238000009423 ventilation Methods 0.000 description 4
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 description 3
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 3
- 229910002091 carbon monoxide Inorganic materials 0.000 description 3
- 230000006835 compression Effects 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 229910001882 dioxygen Inorganic materials 0.000 description 3
- 238000007726 management method Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 238000012549 training Methods 0.000 description 3
- 241001631457 Cannula Species 0.000 description 2
- 206010037544 Purging Diseases 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 238000002664 inhalation therapy Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 208000032953 Device battery issue Diseases 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 230000005355 Hall effect Effects 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000002790 cross-validation Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000003487 electrochemical reaction Methods 0.000 description 1
- 239000007772 electrode material Substances 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000004401 flow injection analysis Methods 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000000153 supplemental effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000011287 therapeutic dose Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461991083P | 2014-05-09 | 2014-05-09 | |
| US201461991028P | 2014-05-09 | 2014-05-09 | |
| US201461991032P | 2014-05-09 | 2014-05-09 | |
| US61/991,032 | 2014-05-09 | ||
| US61/991,028 | 2014-05-09 | ||
| US61/991,083 | 2014-05-09 | ||
| US14/709,308 | 2015-05-11 | ||
| PCT/US2015/030217 WO2015172160A1 (en) | 2014-05-09 | 2015-05-11 | Systems and methods for intelligent gas source management and/or systems and methods for delivery of therapeutic gas and/or enhanced performance verification for therapeutic gas delivery |
| US14/709,316 | 2015-05-11 | ||
| US14/709,308 US10543325B2 (en) | 2014-05-09 | 2015-05-11 | Enhanced performance verification port for therapeutic gas delivery |
| US14/709,298 | 2015-05-11 | ||
| US14/709,316 US10576225B2 (en) | 2014-05-09 | 2015-05-11 | Systems and methods for delivery of therapeutic gas |
| US14/709,298 US10201674B2 (en) | 2014-05-09 | 2015-05-11 | Systems and methods for intelligent gas source management |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017517361A JP2017517361A (ja) | 2017-06-29 |
| JP2017517361A5 true JP2017517361A5 (https=) | 2021-07-15 |
| JP7067925B2 JP7067925B2 (ja) | 2022-05-16 |
Family
ID=54366888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017511572A Active JP7067925B2 (ja) | 2014-05-09 | 2015-05-11 | 高度なガス源を関するシステム及び方法並びに／又は治療ガスの供給システム及び方法並びに／又は治療ガス供給の増強性能検証 |
Country Status (13)
| Country | Link |
|---|---|
| US (13) | US10576225B2 (https=) |
| EP (6) | EP4316555B1 (https=) |
| JP (1) | JP7067925B2 (https=) |
| AU (5) | AU2015255688B2 (https=) |
| CA (6) | CA3138342A1 (https=) |
| CY (1) | CY1121941T1 (https=) |
| DK (4) | DK3581226T3 (https=) |
| ES (4) | ES3046707T3 (https=) |
| FI (3) | FI4316555T3 (https=) |
| MX (6) | MX386591B (https=) |
| PL (3) | PL4316555T3 (https=) |
| PT (4) | PT4309713T (https=) |
| WO (1) | WO2015172160A1 (https=) |
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| US11291868B2 (en) * | 2013-12-20 | 2022-04-05 | B/E Aerospace, Inc. | Pulse saturation oxygen delivery system and method |
| US10869987B2 (en) | 2013-12-20 | 2020-12-22 | B/E Aerospace, Inc | Pulse saturation oxygen delivery system and method |
| US10226592B2 (en) * | 2014-04-01 | 2019-03-12 | Mallinckrodt Hospital Product Ip Limited | Systems and method for delivery of therapeutic gas to patients in need thereof using enhanced breathing circuit gas (BCG) flow measurement |
| EP4316555B1 (en) | 2014-05-09 | 2025-09-17 | Mallinckrodt Pharmaceuticals Ireland Limited | Systems for delivery of therapeutic gas |
| ES2822215T3 (es) | 2014-10-20 | 2021-04-29 | Massachusetts Gen Hospital | Sistemas y métodos de síntesis de óxido nítrico |
| US10596345B2 (en) | 2014-12-31 | 2020-03-24 | Vapotherm, Inc. | Systems and methods for humidity control |
| US10007238B1 (en) * | 2015-01-22 | 2018-06-26 | John C. Taube | Oxygen mixing and delivery |
| FR3038519B1 (fr) | 2015-07-10 | 2022-03-18 | Lantz Jean Sebastien | Dispositif de stimulation de l'air tracheo-bronchique |
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| JP2022533628A (ja) | 2019-05-15 | 2022-07-25 | サード ポール，インコーポレイテッド | 一酸化窒素生成用電極 |
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| FR3133316B1 (fr) | 2022-03-09 | 2024-04-12 | Inosystems | Dispositif de délivrance de NO avec circuit de secours |
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| USD1087129S1 (en) | 2023-02-14 | 2025-08-05 | Mallinckrodt Pharmaceuticals Ireland Limited | Display screen or portion thereof with graphical user interface |
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| FR3148373B1 (fr) | 2023-05-04 | 2025-12-19 | Inosystems | Appareil de délivrance de monoxyde d’azote gazeux en mode pulsé |
| FR3148723A1 (fr) * | 2023-05-16 | 2024-11-22 | Inosystems | Appareil de délivrance de NO à capteurs MOS à longue durée de vie |
| FR3154008A1 (fr) * | 2023-10-12 | 2025-04-18 | Inosystems | Alerte d’inversion de sens de connexion du capteur de débit d’une installation d’administration de monoxyde d’azote |
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