JP2017514829A5 - - Google Patents
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- Publication number
- JP2017514829A5 JP2017514829A5 JP2016565212A JP2016565212A JP2017514829A5 JP 2017514829 A5 JP2017514829 A5 JP 2017514829A5 JP 2016565212 A JP2016565212 A JP 2016565212A JP 2016565212 A JP2016565212 A JP 2016565212A JP 2017514829 A5 JP2017514829 A5 JP 2017514829A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- disease
- amyloidosis
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 201000010099 disease Diseases 0.000 claims 8
- 206010002023 Amyloidosis Diseases 0.000 claims 5
- 206010002022 Amyloidosis Diseases 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 5
- 102000004965 antibodies Human genes 0.000 claims 3
- 108090001123 antibodies Proteins 0.000 claims 3
- 239000002552 dosage form Substances 0.000 claims 2
- 206010001897 Alzheimer's disease Diseases 0.000 claims 1
- KSKLDMGKWDUQCT-DNQXCXABSA-N C(CCCCC(=O)N1[C@H](CCC1)C(=O)OCOC(=O)OC1CCOCC1)(=O)N1[C@H](CCC1)C(=O)OCOC(=O)OC1CCOCC1 Chemical compound C(CCCCC(=O)N1[C@H](CCC1)C(=O)OCOC(=O)OC1CCOCC1)(=O)N1[C@H](CCC1)C(=O)OCOC(=O)OC1CCOCC1 KSKLDMGKWDUQCT-DNQXCXABSA-N 0.000 claims 1
- 208000001072 Type 2 Diabetes Mellitus Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 201000008482 osteoarthritis Diseases 0.000 claims 1
- 239000000546 pharmaceutic aid Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1407506.3A GB201407506D0 (en) | 2014-04-29 | 2014-04-29 | Novel compound |
GB1407506.3 | 2014-04-29 | ||
PCT/EP2015/058998 WO2015165833A1 (en) | 2014-04-29 | 2015-04-27 | A prodrug of 1,1'-(1,6-dioxo-1,6-hexanediyl)bis-d-proline |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2017514829A JP2017514829A (ja) | 2017-06-08 |
JP2017514829A5 true JP2017514829A5 (US20070167479A1-20070719-C00034.png) | 2018-06-14 |
JP6445046B2 JP6445046B2 (ja) | 2018-12-26 |
Family
ID=50972033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016565212A Active JP6445046B2 (ja) | 2014-04-29 | 2015-04-27 | 1,1’−(1,6−ジオキソ−1,6−ヘキサンジイル)ビス−d−プロリンのプロドラッグ |
Country Status (26)
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
GB201518950D0 (en) * | 2015-10-27 | 2015-12-09 | Glaxosmithkline Ip Dev Ltd | Compound |
GB202213162D0 (en) | 2022-09-08 | 2022-10-26 | Cambridge Entpr Ltd | Prodrugs |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT915088E (pt) | 1997-10-31 | 2003-01-31 | Hoffmann La Roche | Derivados de d-prolina |
US6903129B2 (en) * | 2001-12-14 | 2005-06-07 | Hoffman-La Roche Inc. | D-proline prodrugs |
EP1636240A1 (en) | 2003-06-05 | 2006-03-22 | Pfizer Products Inc. | Beta-lactamase inhibitor prodrug |
GB0313386D0 (en) | 2003-06-10 | 2003-07-16 | Univ London | Treatment of disease |
EP1870412A4 (en) | 2005-04-12 | 2009-12-30 | Meiji Seika Kaisha | 2-THIOETHENYLCARBAPENEM DERIVATIVE |
GB0712503D0 (en) | 2007-06-27 | 2007-08-08 | Therapeutics Pentraxin Ltd | Use |
UA108227C2 (xx) | 2010-03-03 | 2015-04-10 | Антигензв'язуючий білок | |
US9737505B2 (en) | 2014-04-29 | 2017-08-22 | Glaxosmithkline Intellectual Property Development Limited | Prodrug of 1,1′-(1,6-dioxo-1,6-hexanediyl)bis-D-proline |
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2014
- 2014-04-29 GB GBGB1407506.3A patent/GB201407506D0/en not_active Ceased
-
2015
- 2015-04-27 EP EP15720312.6A patent/EP3137457B1/en active Active
- 2015-04-27 EA EA201692185A patent/EA032129B1/ru not_active IP Right Cessation
- 2015-04-27 AR ARP150101262A patent/AR100204A1/es active IP Right Grant
- 2015-04-27 MA MA39406A patent/MA39406B1/fr unknown
- 2015-04-27 SG SG11201608371RA patent/SG11201608371RA/en unknown
- 2015-04-27 BR BR112016025129A patent/BR112016025129A2/pt not_active Application Discontinuation
- 2015-04-27 UY UY0001036098A patent/UY36098A/es not_active Application Discontinuation
- 2015-04-27 US US14/787,608 patent/US9701668B2/en active Active
- 2015-04-27 CN CN201580023347.0A patent/CN106459016B/zh not_active Expired - Fee Related
- 2015-04-27 CR CR20160508A patent/CR20160508A/es unknown
- 2015-04-27 MX MX2016014246A patent/MX2016014246A/es active IP Right Grant
- 2015-04-27 ES ES15720312T patent/ES2731253T3/es active Active
- 2015-04-27 KR KR1020167029703A patent/KR20160145617A/ko not_active Application Discontinuation
- 2015-04-27 MY MYPI2016703952A patent/MY191088A/en unknown
- 2015-04-27 CA CA2947060A patent/CA2947060C/en active Active
- 2015-04-27 PE PE2016001934A patent/PE20161558A1/es unknown
- 2015-04-27 AU AU2015252184A patent/AU2015252184B2/en active Active
- 2015-04-27 WO PCT/EP2015/058998 patent/WO2015165833A1/en active Application Filing
- 2015-04-27 JP JP2016565212A patent/JP6445046B2/ja active Active
- 2015-04-27 TW TW104113338A patent/TWI676624B/zh active
- 2015-04-27 UA UAA201612105A patent/UA119871C2/uk unknown
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2016
- 2016-10-09 IL IL248249A patent/IL248249A0/en active IP Right Grant
- 2016-10-10 PH PH12016502006A patent/PH12016502006B1/en unknown
- 2016-10-26 CL CL2016002721A patent/CL2016002721A1/es unknown
- 2016-10-28 DO DO2016000292A patent/DOP2016000292A/es unknown
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2017
- 2017-06-01 US US15/610,984 patent/US9873686B2/en active Active
- 2017-12-11 US US15/837,297 patent/US10597385B2/en active Active
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2020
- 2020-12-01 IL IL279120A patent/IL279120A/en unknown