JP2017512556A5 - - Google Patents
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- JP2017512556A5 JP2017512556A5 JP2016557981A JP2016557981A JP2017512556A5 JP 2017512556 A5 JP2017512556 A5 JP 2017512556A5 JP 2016557981 A JP2016557981 A JP 2016557981A JP 2016557981 A JP2016557981 A JP 2016557981A JP 2017512556 A5 JP2017512556 A5 JP 2017512556A5
- Authority
- JP
- Japan
- Prior art keywords
- exhalation
- section
- segment
- expiratory
- signal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000029058 respiratory gaseous exchange Effects 0.000 claims description 131
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims description 40
- 238000000034 method Methods 0.000 claims description 33
- 230000000241 respiratory effect Effects 0.000 claims description 31
- 238000005259 measurement Methods 0.000 claims description 19
- 238000006243 chemical reaction Methods 0.000 claims description 11
- 238000005070 sampling Methods 0.000 claims description 9
- 210000003437 trachea Anatomy 0.000 claims description 9
- 210000000621 bronchi Anatomy 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 6
- 239000012491 analyte Substances 0.000 claims description 4
- 230000004044 response Effects 0.000 claims description 3
- 238000012795 verification Methods 0.000 claims description 3
- 239000007789 gas Substances 0.000 description 62
- 238000005192 partition Methods 0.000 description 20
- 210000004072 lung Anatomy 0.000 description 13
- 208000006673 asthma Diseases 0.000 description 12
- 238000000638 solvent extraction Methods 0.000 description 12
- 230000004054 inflammatory process Effects 0.000 description 11
- 206010061218 Inflammation Diseases 0.000 description 10
- 239000002085 irritant Substances 0.000 description 7
- 231100000021 irritant Toxicity 0.000 description 7
- 230000000875 corresponding effect Effects 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 4
- 238000013507 mapping Methods 0.000 description 4
- 230000005713 exacerbation Effects 0.000 description 3
- 230000006698 induction Effects 0.000 description 3
- 230000036387 respiratory rate Effects 0.000 description 3
- 206010010904 Convulsion Diseases 0.000 description 2
- 230000001149 cognitive effect Effects 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 230000028709 inflammatory response Effects 0.000 description 2
- 210000003928 nasal cavity Anatomy 0.000 description 2
- 210000001331 nose Anatomy 0.000 description 2
- 238000011369 optimal treatment Methods 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 210000000115 thoracic cavity Anatomy 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 241000717853 Capnia Species 0.000 description 1
- 238000013313 FeNO test Methods 0.000 description 1
- 208000037656 Respiratory Sounds Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000037883 airway inflammation Diseases 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 208000008784 apnea Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461968290P | 2014-03-20 | 2014-03-20 | |
| US61/968,290 | 2014-03-20 | ||
| PCT/US2015/021852 WO2015143384A1 (en) | 2014-03-20 | 2015-03-20 | Selection, segmentation and analysis of exhaled breath for airway disorders assessment |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020182688A Division JP2021020111A (ja) | 2014-03-20 | 2020-10-30 | 呼息中の一酸化窒素レベルを分析するための装置および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017512556A JP2017512556A (ja) | 2017-05-25 |
| JP2017512556A5 true JP2017512556A5 (https=) | 2019-09-12 |
| JP6788503B2 JP6788503B2 (ja) | 2020-11-25 |
Family
ID=54140918
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016557981A Active JP6788503B2 (ja) | 2014-03-20 | 2015-03-20 | 呼息中の一酸化窒素レベルを分析するための装置および方法 |
| JP2020182688A Withdrawn JP2021020111A (ja) | 2014-03-20 | 2020-10-30 | 呼息中の一酸化窒素レベルを分析するための装置および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020182688A Withdrawn JP2021020111A (ja) | 2014-03-20 | 2020-10-30 | 呼息中の一酸化窒素レベルを分析するための装置および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20150265184A1 (https=) |
| EP (1) | EP3119278B1 (https=) |
| JP (2) | JP6788503B2 (https=) |
| CN (1) | CN106456053A (https=) |
| AU (2) | AU2015231003B2 (https=) |
| CA (1) | CA2943243A1 (https=) |
| WO (1) | WO2015143384A1 (https=) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005006988A1 (en) | 2003-06-19 | 2005-01-27 | Everest Biomedical Instruments | Breath end-tidal gas monitor |
| BR112014015145B1 (pt) | 2011-12-21 | 2022-08-16 | Capnia, Inc. | Aparelho para analisar uma concentração de gás em uma respiração de um paciente e método para determinar uma concentração de um gás em uma respiração de um paciente |
| US10499819B2 (en) | 2013-01-08 | 2019-12-10 | Capnia, Inc. | Breath selection for analysis |
| BR112015019326A2 (pt) | 2013-02-12 | 2017-07-18 | Capnia Inc | dispositivo de registro de amostragem e armazenamento para análise de gás respiratório |
| WO2015031850A1 (en) | 2013-08-30 | 2015-03-05 | Capnia, Inc. | Neonatal carbon dioxide measurement system |
| EP3096821B1 (en) * | 2014-01-24 | 2019-11-13 | Circassia Ab | Miniaturized fluid flow regulating device |
| US10806372B2 (en) * | 2014-09-09 | 2020-10-20 | Siemens Healthcare Gmbh | Method and system for simultaneous evaluation of airway wall density and airway wall inflammation |
| US11262354B2 (en) | 2014-10-20 | 2022-03-01 | Boston Scientific Scimed, Inc. | Disposable sensor elements, systems, and related methods |
| US10226201B2 (en) | 2015-10-29 | 2019-03-12 | Invoy Holdings, Llc | Flow regulation device for breath analysis and related method |
| CN109310368A (zh) * | 2016-04-25 | 2019-02-05 | 奥斯通医疗有限公司 | 用于捕获呼吸样本的系统和设备 |
| WO2017187141A1 (en) * | 2016-04-25 | 2017-11-02 | Owlstone Medical Limited | A method for collecting a selective portion of a subject's breath |
| US9933445B1 (en) | 2016-05-16 | 2018-04-03 | Hound Labs, Inc. | System and method for target substance identification |
| EP3439544B1 (en) | 2016-06-15 | 2024-05-15 | Regents of the University of Minnesota | Gas sampling catheters |
| PT109617A (pt) | 2016-09-12 | 2018-03-12 | Faculdade De Ciencias E Tecnologia Da Univ Nova De Lisboa | Sistema para recolha controlada e seletiva de ar exalado e respetivo método de operação |
| CN109862829A (zh) * | 2016-10-21 | 2019-06-07 | 波士顿科学国际有限公司 | 气体采样装置 |
| WO2018213564A1 (en) | 2017-05-19 | 2018-11-22 | Cardiac Pacemakers, Inc. | Systems and methods for assessing the health status of a patient |
| WO2019018299A1 (en) * | 2017-07-17 | 2019-01-24 | University Of Southern California | MEASUREMENT OF NITRIC OXIDE EXHALED AT VARIABLE FLOW |
| US10852264B2 (en) | 2017-07-18 | 2020-12-01 | Boston Scientific Scimed, Inc. | Systems and methods for analyte sensing in physiological gas samples |
| US11187711B1 (en) | 2017-09-11 | 2021-11-30 | Hound Labs, Inc. | Analyte detection from breath samples |
| US11209417B2 (en) | 2017-10-12 | 2021-12-28 | Carrot, Inc. | Breath sensor apparatus and methods of use |
| WO2019222640A1 (en) * | 2018-05-17 | 2019-11-21 | Bellerophon Therapeutics | Method and apparatus for pulsatile delivery of nitric oxide |
| CN109009023A (zh) * | 2018-08-03 | 2018-12-18 | 深圳市大耳马科技有限公司 | 一种呼吸信号的提取方法、装置、处理设备和系统 |
| CN118252493A (zh) * | 2018-08-07 | 2024-06-28 | 罗斯特姆医疗创新有限公司 | 计算机程序产品和用于监测通气患者中的气体交换的方法 |
| US11426097B1 (en) * | 2018-10-17 | 2022-08-30 | Hound Labs, Inc. | Rotary valve assemblies and methods of use for breath sample cartridge systems |
| WO2020081834A1 (en) | 2018-10-19 | 2020-04-23 | Regents Of The University Of Minnesota | Systems and methods for detecting a brain condition |
| EP3861329A1 (en) | 2018-11-27 | 2021-08-11 | Boston Scientific Scimed Inc. | Systems and methods for detecting a health condition |
| CN113196047B (zh) | 2018-12-18 | 2024-08-16 | 明尼苏达大学董事会 | 用于测量化学传感器元件的动力学响应的系统和方法 |
| JP7189011B2 (ja) * | 2018-12-26 | 2022-12-13 | 日本特殊陶業株式会社 | 呼気ガス検知装置 |
| US20200245898A1 (en) | 2019-01-31 | 2020-08-06 | Hound Labs, Inc. | Single-use Microfluidic Cartridge for Detection of Target Chemical Presence in Human Breath |
| US11977086B2 (en) | 2019-03-21 | 2024-05-07 | Hound Labs, Inc. | Biomarker detection from breath samples |
| JP7633176B2 (ja) * | 2019-03-31 | 2025-02-19 | レズメド インコーポレイテッド | ユーザからの１つ以上の分析物を分析する方法、及びシステム |
| US12357185B2 (en) | 2019-06-20 | 2025-07-15 | Hb Innovations, Inc. | System and method for monitoring/detecting and responding to infant breathing |
| US11712180B2 (en) | 2019-06-20 | 2023-08-01 | Hb Innovations, Inc. | System and method for monitoring/detecting and responding to infant breathing |
| US11596326B2 (en) * | 2019-12-06 | 2023-03-07 | Koninklijke Philips N.V. | Systems and methods for metabolic monitoring |
| JP7413407B2 (ja) * | 2019-12-10 | 2024-01-15 | 京セラ株式会社 | 健康状態推定装置および健康状態推定方法 |
| CA3166435A1 (en) | 2019-12-31 | 2021-07-08 | Mcneil Ab | Breath sensor calibration methods and apparatus |
| CA3166438A1 (en) | 2019-12-31 | 2021-07-08 | Mcneil Ab | Breath sensor measurement methods and apparatus |
| US12613212B2 (en) | 2020-05-01 | 2026-04-28 | Regents Of The University Of Minnesota | Non-invasive bladder cancer detection system via liquid and gaseous phase analysis |
| US11933731B1 (en) | 2020-05-13 | 2024-03-19 | Hound Labs, Inc. | Systems and methods using Surface-Enhanced Raman Spectroscopy for detecting tetrahydrocannabinol |
| DE102020123623A1 (de) * | 2020-09-10 | 2022-03-10 | Weinmann Emergency Medical Technology Gmbh + Co. Kg | Verfahren und Vorrichtung zur Messung des Gehalts zumindest eines Gases in Ausatemluft sowie Vorrichtung zur Beatmung |
| DE102020214210A1 (de) * | 2020-11-12 | 2022-05-12 | Robert Bosch Gesellschaft mit beschränkter Haftung | Atemgasanalysegerät |
| US12392769B1 (en) | 2021-01-12 | 2025-08-19 | Hound Labs, Inc. | Ambient contamination in breath analyte detection and measurement |
| US12480907B2 (en) | 2021-04-16 | 2025-11-25 | Regents Of The University Of Minnesota | Systems utilizing graphene varactor hysteresis effects for sample characterization |
| GB2608419B (en) * | 2021-06-30 | 2023-11-01 | Buddi Ltd | A wearable device |
| CN113974606B (zh) * | 2021-10-29 | 2025-04-04 | 重庆安酷科技有限公司 | 一种用于肺弥散功能的检测系统 |
| CN218035914U (zh) * | 2022-06-14 | 2022-12-13 | 惠雨恩科技(深圳)有限公司 | 一种呼气末采集装置 |
| GB2629788A (en) * | 2023-05-09 | 2024-11-13 | Bioxhale Ltd | Fluid collection and sampling device |
| IL303095B2 (en) * | 2023-05-21 | 2025-01-01 | Technopulm Ltd | Method and system for determining a lung function characteristic |
| GB2634017A (en) * | 2023-09-25 | 2025-04-02 | Zenamed Ltd | Apparatus for and method of measuring a substance in a breath sample |
| CN120837054B (zh) * | 2025-09-22 | 2025-12-02 | 苏州创莱电子科技有限公司 | 一种评估呼吸系统生理参数的医疗装置 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6010459A (en) * | 1996-04-09 | 2000-01-04 | Silkoff; Philip E. | Method and apparatus for the measurement of components of exhaled breath in humans |
| IL121793A (en) * | 1997-09-17 | 2008-06-05 | Lewis Coleman | Isotopic gas analyzer |
| SE9701150D0 (sv) * | 1997-03-27 | 1997-03-27 | Nitrograf Ab | Anordning för att utvärdera NO-halten i en utandad luftström |
| AU6515000A (en) * | 1999-08-02 | 2001-02-19 | Healthetech, Inc. | Metabolic calorimeter employing respiratory gas analysis |
| AU2002250237A1 (en) * | 2001-03-02 | 2002-09-19 | Healthetech, Inc. | A system and method of metabolic rate measurement |
| US20070167853A1 (en) * | 2002-01-22 | 2007-07-19 | Melker Richard J | System and method for monitoring health using exhaled breath |
| US6929637B2 (en) * | 2002-02-21 | 2005-08-16 | Spiration, Inc. | Device and method for intra-bronchial provision of a therapeutic agent |
| IL148468A (en) * | 2002-03-03 | 2012-12-31 | Exalenz Bioscience Ltd | Breath collection system |
| US8672852B2 (en) * | 2002-12-13 | 2014-03-18 | Intercure Ltd. | Apparatus and method for beneficial modification of biorhythmic activity |
| US20060200037A1 (en) * | 2005-03-02 | 2006-09-07 | Falasco Marianne R | System and method for selectively collecting exhaled air |
| ITRM20050217A1 (it) * | 2005-05-06 | 2006-11-07 | Ginevri S R L | Procedimento per ventilazione nasale e relativo apparato, in particolare per la ventilazione assistita flusso-sincronizzata neonatale. |
| US20080009762A1 (en) * | 2006-06-27 | 2008-01-10 | Medtronic Emergency Response Systems, Inc. | Method and apparatus for interpreting capnographic data |
| EP2099361A4 (en) * | 2007-01-04 | 2013-03-06 | Oridion Medical 1987 Ltd | CAPNOGRAPHY DEVICE AND METHOD |
| US9687176B2 (en) * | 2008-10-16 | 2017-06-27 | Vanderbilt University | Oral end tidal carbon dioxide probe for diagnosing pulmonary arterial hypertension |
| US9763600B2 (en) * | 2010-02-17 | 2017-09-19 | Koninklijke Philips N.V. | Nitric oxide measurement method and apparatus |
| EP2651293B1 (en) * | 2010-12-17 | 2015-02-25 | Koninklijke Philips N.V. | System and method for determining one or more breathing parameters of a subject |
| BR112014015145B1 (pt) * | 2011-12-21 | 2022-08-16 | Capnia, Inc. | Aparelho para analisar uma concentração de gás em uma respiração de um paciente e método para determinar uma concentração de um gás em uma respiração de um paciente |
-
2015
- 2015-03-20 CN CN201580023183.1A patent/CN106456053A/zh active Pending
- 2015-03-20 JP JP2016557981A patent/JP6788503B2/ja active Active
- 2015-03-20 CA CA2943243A patent/CA2943243A1/en not_active Abandoned
- 2015-03-20 US US14/664,728 patent/US20150265184A1/en not_active Abandoned
- 2015-03-20 AU AU2015231003A patent/AU2015231003B2/en active Active
- 2015-03-20 EP EP15764503.7A patent/EP3119278B1/en active Active
- 2015-03-20 WO PCT/US2015/021852 patent/WO2015143384A1/en not_active Ceased
-
2019
- 2019-04-16 US US16/386,034 patent/US20200046254A1/en not_active Abandoned
-
2020
- 2020-02-20 AU AU2020201244A patent/AU2020201244B2/en active Active
- 2020-10-30 JP JP2020182688A patent/JP2021020111A/ja not_active Withdrawn
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