JP2017512066A - フィラリア線虫ワクチン、ポリペプチド、および核酸 - Google Patents

フィラリア線虫ワクチン、ポリペプチド、および核酸 Download PDF

Info

Publication number
JP2017512066A
JP2017512066A JP2016568144A JP2016568144A JP2017512066A JP 2017512066 A JP2017512066 A JP 2017512066A JP 2016568144 A JP2016568144 A JP 2016568144A JP 2016568144 A JP2016568144 A JP 2016568144A JP 2017512066 A JP2017512066 A JP 2017512066A
Authority
JP
Japan
Prior art keywords
polypeptide
shk
nucleic acid
protein
domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016568144A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017512066A5 (enExample
Inventor
メイクピース,ベン
テイラー,デイヴィッド
ババヤン,サイモン
アームストロング,スチュアート
ブラクスター,マーク
Original Assignee
ザ・ユニヴァーシティ・オヴ・リヴァプール
エディンバラ・ユニヴァーシティ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ・ユニヴァーシティ・オヴ・リヴァプール, エディンバラ・ユニヴァーシティ filed Critical ザ・ユニヴァーシティ・オヴ・リヴァプール
Publication of JP2017512066A publication Critical patent/JP2017512066A/ja
Publication of JP2017512066A5 publication Critical patent/JP2017512066A5/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0003Invertebrate antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2016568144A 2014-02-11 2015-02-11 フィラリア線虫ワクチン、ポリペプチド、および核酸 Pending JP2017512066A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1402352.7A GB201402352D0 (en) 2014-02-11 2014-02-11 Vaccines, polypeptides, and nucleic acids
GB1402352.7 2014-02-11
PCT/GB2015/050380 WO2015121646A1 (en) 2014-02-11 2015-02-11 Filarial nematode vaccines, polypeptides, and nucleic acids

Publications (2)

Publication Number Publication Date
JP2017512066A true JP2017512066A (ja) 2017-05-18
JP2017512066A5 JP2017512066A5 (enExample) 2018-03-15

Family

ID=50390804

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016568144A Pending JP2017512066A (ja) 2014-02-11 2015-02-11 フィラリア線虫ワクチン、ポリペプチド、および核酸

Country Status (7)

Country Link
US (2) US9994624B2 (enExample)
EP (2) EP3693008A1 (enExample)
JP (1) JP2017512066A (enExample)
AU (2) AU2015216783A1 (enExample)
CA (1) CA2939236C (enExample)
GB (1) GB201402352D0 (enExample)
WO (1) WO2015121646A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201402352D0 (en) 2014-02-11 2014-03-26 Univ Liverpool Vaccines, polypeptides, and nucleic acids
WO2017173369A1 (en) 2016-04-01 2017-10-05 New York Blood Center, Inc. Biomakers and immunogenic compositions for filarial parasites
WO2017176950A2 (en) 2016-04-07 2017-10-12 Merial, Inc. Heartworm vaccine, methods and uses thereof
MX2024004078A (es) * 2021-10-04 2024-04-18 Agresearch Ltd Vacuna contra nematodos.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265198B1 (en) 1994-05-26 2001-07-24 Heska Corporation Parasite astacin metalloendopeptidase proteins
MY160430A (en) 2008-12-12 2017-03-15 Univ Sains Malaysia Recombinant antigen for detection of toxocariasis
US20130236490A1 (en) 2010-11-15 2013-09-12 The Board Of Trustees Of The University Of Illinois Multivalent Vaccine for Filariasis
GB201402352D0 (en) 2014-02-11 2014-03-26 Univ Liverpool Vaccines, polypeptides, and nucleic acids

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK, ACCESSION NO: BF400446, DEFINITION:SWOV3MCAM46A10SK ONCHOCERCA VOLVULUS MOLTING L3, JPN6018050006, ISSN: 0003942038 *
DATABASE GENBANK, ACCESSION NO:AA228632, DEFINITION:RRAMCA404SK BRUGIA MALAYI ADULT MALE CDNA (SAW94, JPN6018050007, ISSN: 0003942039 *
DATABASE GENBANK, ACCESSION NO:DN558110, DEFINITION:LS_AF1_32F04_T7 LITOMOSOIDES SIGMODONTIS ADULT F, JPN6018050005, ISSN: 0003942037 *

Also Published As

Publication number Publication date
US9994624B2 (en) 2018-06-12
US10919944B2 (en) 2021-02-16
AU2019222839A1 (en) 2019-09-19
US20170051024A1 (en) 2017-02-23
CA2939236A1 (en) 2015-08-20
WO2015121646A1 (en) 2015-08-20
EP3693008A1 (en) 2020-08-12
EP3104876A1 (en) 2016-12-21
GB201402352D0 (en) 2014-03-26
AU2019222839B2 (en) 2021-07-08
US20180355002A1 (en) 2018-12-13
AU2015216783A1 (en) 2016-09-22
CA2939236C (en) 2023-02-21

Similar Documents

Publication Publication Date Title
Cortes et al. A review on bovine besnoitiosis: a disease with economic impact in herd health management, caused by Besnoitia besnoiti (Franco and Borges, 1916)
McNeilly et al. Immune modulation by helminth parasites of ruminants: implications for vaccine development and host immune competence
Moreno et al. Stage-and gender-specific proteomic analysis of Brugia malayi excretory-secretory products
Hewitson et al. Secretion of protective antigens by tissue-stage nematode larvae revealed by proteomic analysis and vaccination-induced sterile immunity
Yue et al. Molecular characterization of a Trichinella spiralis serine proteinase
Tang et al. Characterisation of a high-frequency gene encoding a strongly antigenic cystatin-like protein from Trichinella spiralis at its early invasion stage
Yan et al. Vaccination of goats with DNA vaccine encoding Dim-1 induced partial protection against Haemonchus contortus: A preliminary experimental study
AU2019222839B2 (en) Filarial nematode vaccines, polypeptides, and nucleic acids
EP2358745A1 (en) Leukolectins and uses thereof
Bai et al. Molecular characterization of a novel cathepsin L from Trichinella spiralis and its participation in invasion, development and reproduction
Noon et al. A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection
Gao et al. Extracellular vesicles from Trichinella spiralis: Proteomic analysis and protective immunity
Xu et al. Vaccination with a DNase II recombinant protein against Trichinella spiralis infection in pigs
Liao et al. Molecular characterization of Rhipicephalus (Boophilus) microplus Bm86 homologue from Haemaphysalis longicornis ticks
Nisbet et al. Teladorsagia circumcincta: activation-associated secreted proteins in excretory/secretory products of fourth stage larvae are targets of early IgA responses in infected sheep
Zhou et al. Expression of Caenorhabditis elegans-expressed Trans-HPS, partial aminopeptidase H11 from Haemonchus contortus
Tak et al. A comparative analysis of various antigenic proteins found in Haemonchus contortus—a review
Wang et al. Haemonchus contortus hepatocellular carcinoma-associated antigen 59 with poly (lactic-co-glycolic acid): a promising nanovaccine candidate against Haemonchus contortus infection
Geldhof et al. Characterisation of the two most abundant genes in the Haemonchus contortus expressed sequence tag dataset
Chen et al. Expression and immune response analysis of Schistosoma japonicum VAL-1, a homologue of vespid venom allergens
Zhang et al. Immune responses in mice vaccinated with a DNA vaccine expressing a new elastase from Trichinella spiralis.
Avila Soria Molecular characterization of Carukia barnesi and Malo kingi, cnidaria; Cubozoa; Carybdeidae
Nisbet et al. Immune recognition of the surface associated antigen, Tc‐SAA‐1, from infective larvae of Teladorsagia circumcincta
JP2022174692A (ja) 抗ワクモワクチン組成物及びその使用
WO2016149460A1 (en) Immunogenic compositions and vaccines for preventing or treating filarial disease

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180202

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180202

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20181211

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20181218

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190312

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20190514

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190618

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20191112