JP2017502023A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017502023A5 JP2017502023A5 JP2016540993A JP2016540993A JP2017502023A5 JP 2017502023 A5 JP2017502023 A5 JP 2017502023A5 JP 2016540993 A JP2016540993 A JP 2016540993A JP 2016540993 A JP2016540993 A JP 2016540993A JP 2017502023 A5 JP2017502023 A5 JP 2017502023A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- binding fragment
- macular degeneration
- age
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 22
- 102000036639 antigens Human genes 0.000 claims 22
- 108091007433 antigens Proteins 0.000 claims 22
- 239000012634 fragment Substances 0.000 claims 22
- 206010064930 age-related macular degeneration Diseases 0.000 claims 7
- 208000002780 macular degeneration Diseases 0.000 claims 5
- 208000008069 Geographic Atrophy Diseases 0.000 claims 3
- 230000004913 activation Effects 0.000 claims 3
- 230000037361 pathway Effects 0.000 claims 3
- 208000000208 Wet Macular Degeneration Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 208000031471 Macular fibrosis Diseases 0.000 claims 1
- 208000031472 Retinal fibrosis Diseases 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 230000000740 bleeding effect Effects 0.000 claims 1
- 230000024203 complement activation Effects 0.000 claims 1
- 208000011325 dry age related macular degeneration Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000008397 ocular pathology Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361920541P | 2013-12-24 | 2013-12-24 | |
| US61/920,541 | 2013-12-24 | ||
| PCT/US2014/049938 WO2015099838A2 (en) | 2013-12-24 | 2014-08-06 | Compositions and methods of treating ocular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017502023A JP2017502023A (ja) | 2017-01-19 |
| JP2017502023A5 true JP2017502023A5 (enExample) | 2017-09-14 |
Family
ID=53479755
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016540993A Pending JP2017502023A (ja) | 2013-12-24 | 2014-08-06 | 眼疾患を治療する組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10183989B2 (enExample) |
| EP (1) | EP3086809A4 (enExample) |
| JP (1) | JP2017502023A (enExample) |
| AU (1) | AU2014370404A1 (enExample) |
| CA (1) | CA2934462A1 (enExample) |
| WO (1) | WO2015099838A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| IL261188B (en) | 2016-03-04 | 2022-08-01 | Jn Biosciences Llc | An anti-tigit antibody that binds to the tigit polypeptide on one or more amino acid residues |
| CA3029003A1 (en) | 2016-06-27 | 2018-01-04 | The Regents Of The University Of California | Cancer treatment combinations |
| WO2019033081A1 (en) * | 2017-08-11 | 2019-02-14 | Massachusetts Eye And Ear Infirmary | INHIBITION OF THE SUPPLEMENTARY ALTERNA PATHWAY FOR THE TREATMENT OF RETINAL ISCHEMIC LESION AND GLAUCOMA |
| US20190247560A1 (en) | 2018-02-13 | 2019-08-15 | Gambro Lundia Ab | Extracorporeal devices and methods of treating complement factor related diseases |
| BR112020019907A2 (pt) | 2018-04-03 | 2021-01-05 | Ngm Biopharmaceuticals, Inc. | Agentes de ligação a c3 e métodos de uso dos mesmos |
| EP3586865A1 (en) * | 2018-06-21 | 2020-01-01 | Charité - Universitätsmedizin Berlin | Complement anaphylatoxin binders and their use in treatment of a subject having an ocular wound and/or fibrosis |
| CN109999015A (zh) * | 2019-04-24 | 2019-07-12 | 江苏省中医药研究院 | 紫草素在制备预防或治疗房颤药物中的用途 |
| CR20220611A (es) | 2020-06-02 | 2023-06-07 | Arcus Biosciences Inc | Anticuerpos anti-tigit |
| IL301762A (en) * | 2020-10-07 | 2023-05-01 | Line 6 Biotechnology Inc | Methods and materials for the treatment of eye diseases |
| US11981727B2 (en) | 2021-08-31 | 2024-05-14 | Novelmed Therapeutics, Inc | Monospecific and bispecific antibodies and antigen binding fragments thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030171320A1 (en) * | 2001-11-09 | 2003-09-11 | Guyer David R. | Methods for treating ocular neovascular diseases |
| DK1931379T3 (da) * | 2005-10-07 | 2013-08-19 | Sec Dep For Health | Proteiner med forbedret opløselighed samt fremgangsmåder til frembringelse og anvendelse af samme |
| ES2551202T5 (es) | 2005-11-04 | 2018-11-30 | Genentech, Inc. | Uso de inhibidores de la vía del complemento para tratar enfermedades oculares |
| HUE026496T2 (en) | 2006-03-08 | 2016-06-28 | Archemix Llc | Complement-binding aptamers and anti-C5 agents for treating eye diseases |
| WO2011112850A2 (en) | 2010-03-10 | 2011-09-15 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| US9745367B2 (en) * | 2007-03-23 | 2017-08-29 | Novelmed Theraputics, Inc. | Alternative pathway specific antibodies for treating arthritis |
| US20100015139A1 (en) | 2008-07-10 | 2010-01-21 | Rekha Bansal | METHOD OF INHIBITING COMPLEMENT ACTIVATION WITH FACTOR Ba SPECIFIC ANTIBODIES AND USE THEREOF |
| AU2008262048B2 (en) * | 2007-06-07 | 2013-09-26 | Genentech, Inc. | C3b antibodies and methods for the prevention and treatment of complement- associated disorders |
| US20100291106A1 (en) | 2009-05-06 | 2010-11-18 | Novartis Ag | Compositions and methods for antibodies targeting complement protein c3b |
| US20190202898A9 (en) * | 2012-04-03 | 2019-07-04 | Novelmed Therapeutics, Inc. | AGLYCOSYLATED ANTI-C3b ANTIBODIES AND USES THEREOF |
| EP2834271B1 (en) | 2012-04-03 | 2019-01-16 | NovelMed Therapeutics, Inc. | Humanized and chimeric anti-factor bb antibodies and uses thereof |
| CN104220453B (zh) * | 2012-04-03 | 2018-03-09 | 诺沃姆德治疗公司 | 人源化的嵌合抗因子c3抗体及其用途 |
-
2014
- 2014-08-06 US US15/106,017 patent/US10183989B2/en active Active
- 2014-08-06 CA CA2934462A patent/CA2934462A1/en not_active Abandoned
- 2014-08-06 WO PCT/US2014/049938 patent/WO2015099838A2/en not_active Ceased
- 2014-08-06 AU AU2014370404A patent/AU2014370404A1/en not_active Abandoned
- 2014-08-06 EP EP14874978.1A patent/EP3086809A4/en not_active Withdrawn
- 2014-08-06 JP JP2016540993A patent/JP2017502023A/ja active Pending
-
2019
- 2019-01-22 US US16/254,173 patent/US10696740B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017502023A5 (enExample) | ||
| EA201791093A1 (ru) | Антитела к cd47, способы и применение | |
| EA201890305A1 (ru) | Гуманизированные или химерные cd3-антитела | |
| EA201891732A1 (ru) | Биспецифичные связывающие белки для pd-l1 и kdr | |
| PE20240111A1 (es) | Moleculas de union a pd-1 y metodos de uso de las mismas | |
| EA201890834A1 (ru) | Агонистические антитела, специфически связывающие человеческий cd40, и способы их применения | |
| NZ706377A (en) | Il-6 antagonists and uses thereof | |
| EA201791168A1 (ru) | Способы и составы для лечения сосудистых заболеваний глаз | |
| EA201890285A1 (ru) | Антитела против pd-1, активируемые антитела против pd-1 и способы их применения | |
| WO2014186622A3 (en) | Methods of treatment for guillain-barre syndrome | |
| PH12015501505B1 (en) | Antibodies that bind to tl1a and their uses | |
| NZ630610A (en) | Tau peptides, anti-tau antibodies, and methods of use thereof | |
| JP2018504907A5 (enExample) | ||
| EA201591113A1 (ru) | Антитела против антигена 2 дендритных клеток крови и их применение | |
| BR112015022123A8 (pt) | Anticorpos, fragmentos de ligação ao antígeno dos mesmos que se ligam especificamente à hepcidina ou um peptídeo de hepcidina, uso, meio contentor e kit | |
| EA201791712A1 (ru) | Антитела к транстиретину | |
| HK1208499A1 (en) | Dual receptor antagonistic antigen-binding proteins and uses thereof | |
| MX366359B (es) | Anticuerpos humanizados contra la molecula de adhesion celular relacionada al antigeno carcinoembrionico 1 (ceacam1). | |
| EA201991464A1 (ru) | АНТИТЕЛО К α-СИНУКЛЕИНУ И ЕГО ПРИМЕНЕНИЕ | |
| PH12017500699A1 (en) | Antibodies that bind to ccr6 and their uses | |
| NZ730186A (en) | Humanized anti-hepcidin antibodies and uses thereof | |
| WO2016057683A3 (en) | Novel anti-nodal antibodies and methods of using same | |
| WO2017079443A8 (en) | Compositions comprising il6r antibodies for the treatment of uveitis and macular edema and methods of using same | |
| WO2015187521A3 (en) | Anti-blys antibodies | |
| WO2018071504A3 (en) | Methods of treating diseases with il-23a antibody |