JP2017189125A - Sample observation apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a sample observation apparatus capable of shortening a circuit length and improving noise immunity.SOLUTION: According to the present invention, a sample observation apparatus comprises a sealed housing 10; a first moving member 29X and a second moving member 29Y, which move in an X axis direction and a Y axis direction, perpendicular to each other in the housing. Each of them comprises: an electric substrate 62 disposed on a second moving member and electrically connected to an image pickup device 43a, an image pickup device-driving substrate 43b, and an electric substrate 62 electrically connecting to the image pickup device-driving substrate 43b and performing image processing of an image pickup signal; a connection wiring portion 71 connected to the imaging device-driving substrate 43 b and the electric substrate 62; a memory card detachably attached to the electric substrate 62 that stores image pickup signal; and a wireless LAN board 72 for wirelessly transmitting the image pickup signal to the outside.SELECTED DRAWING: Figure 8

Description

  The present invention relates to a sample observation apparatus for observing a sample such as a cell in an incubator.

  Conventionally, an image pickup unit including an image pickup optical system and an image pickup element is linearly moved in each of two directions of an X axis and a Y axis perpendicular to each other, and the image pickup unit can be freely moved in a plane parallel to the XY plane. It is possible to automatically scan the entire image of a sample such as a cell in the incubator and arbitrarily observe a desired part of the sample such as a cell in the incubator. As for the sample observation apparatus configured so as to be able to perform, various types are proposed by, for example, Japanese Patent Laid-Open No. 5-232047 (Patent Document 1), Japanese Patent Application Laid-Open No. 2008-92882 (Patent Document 2) and the like. , Has also been put to practical use.

  In the sample observation apparatus disclosed in Japanese Patent Laid-Open Nos. 5-232047 and 2008-92882, an image pickup unit is driven by a drive mechanism that can be freely moved in a plane parallel to the XY plane. Is moved, a control board for driving the imaging unit is disposed in the housing of the sample observation apparatus.

  In addition, the imaging unit and the control board are connected by a flexible connection cable, and an imaging signal output from the imaging signal is transmitted together with a driving signal of the imaging element.

Japanese Patent Laid-Open No. 5-232047 JP 2008-92882 A

  However, since the signal transmitted through the connection cable described above is a high-frequency signal, the influence of external noise may not be negligible in a state where the imaging element and the control board are separated and the connection cable is routed for a long distance. .

  Therefore, in order to reduce the influence of external noise, conventionally, for example, it has been necessary to take measures such as providing a shielding measure for the connection cable itself or arranging a noise reducing component in the circuit.

  Specifically, when the control board as described above is arranged in and around the range in which the moving member having the imaging unit moves in the observation apparatus, or the wall of the apparatus housing and the periphery thereof, the arrangement position or connection of the control board Depending on the wiring position of the cable, it is easily affected by external noise, and countermeasures are required.

  On the other hand, when the control board as described above is arranged near the wall of the apparatus housing, there arises a problem of miniaturization.

  The present invention has been made in view of the above-described points, and an object of the present invention is to devise an arrangement position of a control board connected to an imaging unit, to realize a short circuit length and to reduce noise. It is an object of the present invention to provide a sample observation apparatus that improves resistance and realizes a small apparatus.

  To achieve the above object, a sample observation apparatus according to an aspect of the present invention includes a sealed box body, and a first moving member that moves in a first direction along a first guide portion in the box body. And an image pickup optical system arranged extending in the first direction and an image pickup element for converting subject light that has passed through the image pickup optical system into an electrical signal, together with the first moving member, A second moving member that moves in a direction and moves in a second direction perpendicular to the first direction along the second guide portion with respect to the first moving member after the movement, and the second A first imaging control circuit board disposed on the moving member for controlling the image sensor; and a second imaging member disposed on the second moving member and electrically connected to the first imaging control circuit board. A second imaging control circuit board for processing a signal from the control circuit; The first imaging control circuit board is arranged around the imaging element, and the second imaging control circuit board is arranged on the lower side in the optical axis direction of the first lens that is a subject incident portion of the imaging imaging optical system. Yes.

  According to the present invention, it is possible to provide a sample observation apparatus that devise the arrangement position of a control board connected to an imaging unit, realize a short circuit length, improve noise resistance, and realize a small apparatus. Can do.

The system block diagram which shows the outline of the whole structure of the sample observation system containing the sample observation apparatus of one Embodiment of this invention. 1 is an external perspective view showing the external appearance of a sample observation apparatus according to an embodiment of the present invention. FIG. 2 is an external perspective view showing a state in which the incubator (culture flask) is removed from the sample observation apparatus of FIG. FIG. 2 is an external perspective view showing the internal configuration of the sample observation apparatus shown in FIG. The top view which removed the cover of the sample observation apparatus of FIG. 2, and was seen from the upper surface side Sectional drawing which follows the [6]-[6] line of FIG. Sectional drawing which follows the [7]-[7] line of FIG. Sectional drawing which follows the [8]-[8] line of FIG. Sectional drawing which follows the [9]-[9] line of FIG. 2 is an external perspective view mainly showing the upper surface side of the second moving member in the sample observation apparatus of FIG. 2 is an external perspective view mainly showing the back side of the second moving member in the sample observation apparatus of FIG. The top view seen from the upper surface side of the 2nd moving member in the sample observation apparatus of FIG. Sectional drawing which follows the [13]-[13] line of FIG. Sectional drawing which follows the [14]-[14] line of FIG. Sectional drawing which shows the state at the time of using the sample observation apparatus of FIG. 2 (equivalent to the cross section which followed the [8]-[8] line of FIG. 5).

  The present invention will be described below with reference to the illustrated embodiments. Each drawing used in the following description is schematically shown. In order to show each component in a size that can be recognized on the drawing, the dimensional relationship and scale of each member are different for each component. May be shown. Accordingly, the present invention is limited only to the illustrated embodiments with respect to the quantity of components, the shape of the components, the size ratio of the components, the relative positional relationship of the components, and the like described in the drawings. It is not something.

[One Embodiment]
FIG. 1 is a system configuration diagram showing an outline of the overall configuration of a sample observation system including a sample observation apparatus according to an embodiment of the present invention. FIG. 2 is an external perspective view showing the external appearance of the sample observation apparatus of the present embodiment. FIG. 3 is an external perspective view showing a state in which the incubator (culture flask) is removed from the sample observation apparatus of FIG.

  4 to 9 are views showing the internal configuration of the sample observation apparatus shown in FIG. Among these, FIG. 4 is an external perspective view. FIG. 5 is a plan view seen from the upper surface side. 6 is a cross-sectional view taken along line [6]-[6] in FIG. FIG. 7 is a cross-sectional view taken along line [7]-[7] in FIG. 8 is a cross-sectional view taken along line [8]-[8] in FIG. FIG. 9 is a cross-sectional view taken along line [9]-[9] in FIG.

  10 to 14 are views showing only the second moving member in the sample observation apparatus of FIG. Among these, FIG. 10 is an external perspective view mainly showing the upper surface side. FIG. 11 is an external perspective view mainly showing the back side. FIG. 12 is a plan view seen from the upper surface side. 13 is a cross-sectional view taken along the line [13]-[13] in FIG. FIG. 14 is an enlarged cross-sectional view of a main part showing the part in an enlarged manner mainly to show the holding structure of the moving optical system. 14 is a cross section taken along the line [14]-[14] in FIG.

  FIG. 15 is a cross-sectional view showing a state when the incubator is attached and used in the sample observation apparatus of the present embodiment. 15 corresponds to a cross section taken along line [8]-[8] in FIG. 5 in the sample observation apparatus with the incubator attached.

  First, before describing the detailed configuration of the sample observation apparatus according to an embodiment of the present invention, an outline of the overall configuration of the sample observation system including the sample observation apparatus according to the present embodiment will be mainly described below with reference to FIG. To do.

  A sample observation system 100 including the sample observation device 1 of the present embodiment is mainly configured by the sample observation device 1 of the present embodiment, a thermostat 101, a control device 102, an input device 103, a display device 104, and the like. Yes.

  The sample observation apparatus 1 of the present embodiment is used in a state where it is stored and mounted inside the thermostat 101. The incubator 101 is a device having a function of keeping the temperature constant, and is called a so-called incubator. There are various types of thermostats 101, but those that have been put into practical use and widely used in the past are applied, and detailed description of the configuration is omitted.

  The control apparatus 102 is connected to the sample observation apparatus 1 of the present embodiment via, for example, a wired connection means such as a connection cable (USB (Universal Serial Bus) connection) or a wireless connection means (not shown). Are electrically connected to control the operation of the sample observation apparatus 1, receive image data acquired by the sample observation apparatus 1, store the received image data in a storage medium, and receive In addition to executing various types of image signal processing such as analysis and analysis of the image data, the sample observation apparatus 1 is powered. As the control device 102, for example, a small personal computer or the like widely used can be applied. For that purpose, it can be operated by appropriately preparing various control programs suitable for them.

  Note that the power supply to the sample observation apparatus 1 is not limited to the power supply means via the control device 102, and power is supplied from a commercial power source provided outside the thermostat 101 using a power cable (not shown). Alternatively, power may be supplied from a storage battery or the like installed in the thermostat 101 or outside.

  The control device 102 is electrically connected with an input device 103 and a display device 104 as peripheral devices. The input device 103 is a device for inputting an instruction to the control device 102 by a user (user). Examples of the input device 103 include a keyboard, a pointing device such as a mouse, a trackball, and a joystick. A user (user) can use these input devices 103 to input control instructions to the control device 102 and instructions for various signal processing.

  The display device 104 visually displays various displays based on a control program operated by the control device 102 and images based on the image data acquired by the sample observation device 1 and received by the control device 102. It is a device. As the display device 104, a liquid crystal display monitor or the like that is widely used can be applied.

  Next, the detailed structure of the sample observation apparatus 1 of this embodiment is demonstrated below using FIGS.

  The sample observation apparatus 1 according to the present embodiment linearly moves the imaging unit 40 and the like provided therein in two directions of the X axis and the Y axis that are orthogonal to each other, and the imaging unit 40 and the like are parallel to the XY plane. It is a sample observation device provided with a drive mechanism that can be freely moved in a smooth plane. The sample observation apparatus 1 is configured to observe the sample in the incubator 13 by disposing the incubator 13 on the mounting portion having the light transmission portion 12a.

  In the following description, as shown in FIG. 2 and the like, the direction along the long side of the box 10 (described later) in the sample observation apparatus 1 is referred to as the X axis, and the direction along the X axis is the first direction. Let's say direction. In addition, a direction along the short side of the box 10 and perpendicular to the X axis is referred to as a Y axis, and a direction along the Y axis is referred to as a second direction.

  For this purpose, the sample observation apparatus 1 of the present embodiment includes a sealed rectangular parallelepiped box 10 and an incubator 13 placed on one surface of the box 10 as shown in FIGS. It is configured. In addition, since FIG. 3 has shown the state which removed the incubator 13, the incubator 13 is not illustrated in FIG.

  The case 10 is composed of a chassis 11 having an opening on one surface, and a lid 12 (lid) that covers the opening of the casing 11 in a watertight manner. Although the details will be described later, various constituent members of the sample observation apparatus 1 are accommodated in the housing 11. A plurality of connection connectors 16 and 17 are provided on the outer wall surface of one side surface (front side) of the housing 11. As the plurality of connection connectors 16 and 17, for example, a power cable for supplying power to the sample observation apparatus 1, a control signal to the sample observation apparatus 1, or a data signal output from the sample observation apparatus 1 is used. It is a connector corresponding to a signal transmission cable (for example, a USB cable) for transmitting various signals including it.

  The plurality of connection connectors 16 and 17 are disposed inside the housing 11 and are connected to the corresponding electric boards (not shown in FIG. 4, etc., see reference numeral 55 in FIG. 15 described later). . For example, a power supply circuit and a communication circuit are mounted on the electric board (55; FIG. 15).

  Further, a flexible wiring cable 61 (to be described later) is connected to the electric board 55 so that a predetermined power supply and predetermined data are transmitted to the electric board 62 (to be described later) via the flexible wiring cable 61. It has become.

  In the housing 11, the wall surface on one side surface where the plurality of connection connectors 16 and 17 are disposed is referred to as a front wall surface. In the following description, the two side walls provided orthogonal to the front wall surface and disposed opposite to each other are referred to as a first side wall 11a and a second side wall 11b, respectively ( (See FIG. 4). Further, a surface facing the opening of the housing 11 is referred to as a bottom surface.

  The lid body 12 is configured to have a light transmission portion 12a and is a placement portion for placing the incubator 13 thereon. The light transmission part 12a is, for example, a window part that is a rectangular through-hole, and a transparent thin plate member that is fitted and arranged in the window part and formed using a glass material, a resin material, or the like. Is formed.

  The incubator 13 is a container having a box shape for producing a culture medium and culturing a sample such as a microorganism such as bacteria and a cell. The incubator 13 is placed on the light transmission part 12a of the lid 12 of the box 10 when the sample observation apparatus 1 is used.

  When the incubator 13 is placed on the light transmitting portion 12a, the side facing the light transmitting portion 12a, that is, the bottom surface side of the incubator 13 is formed in a flat dish shape, and the flat dish-shaped bottom surface is It is formed in a transparent thin plate shape. The other surfaces other than the bottom surface of the incubator 13 are also formed with reflective surfaces that can reflect light and have a flat surface. The reflecting surface receives illumination light emitted from an illumination light source provided inside the box 10 of the sample observation apparatus 1 and entering the incubator 13 through the light transmitting portion 12a. It is a reflection. Thereby, since the sample such as the cells in the flat dish-shaped bottom surface of the incubator 13 is illuminated by the illumination light from the reflecting surface, the sample observation apparatus 1 uses the sample such as the cells in the incubator 13. Can be observed by transmitted light.

  The lid 12 is provided with a plurality of operation members 14 and a plurality of state display portions 15. The plurality of operation members 14 are arranged inside the box 10 of a driven unit (imaging unit 40 or the like; details will be described later) in the sample observation device 1 before the sample observation device 1 is installed in the thermostat 101, for example. This is an operation switch or the like for performing manual position adjustment and the like. The plurality of status display units 15 are members that are provided to display the status of which operation member has been operated, for example, by being turned on when one of the plurality of operation members 14 is operated. For this purpose, each of the plurality of status display portions 15 is provided in the vicinity of each of the plurality of operation members 14. For example, a light emitter such as an LED (light emitting diode) is used as the plurality of status display units 15.

  The plurality of operation members 14 and the plurality of status display units 15 are disposed inside the housing 11 and each correspond to an electric board (not shown in FIG. 4 or the like; see reference numeral 54 in FIG. 15 described later). )It is connected to the. On this electric board (54; FIG. 15), for example, a switch member that receives an operation input of the operation member, a signal processing circuit that processes the input signal, a drive circuit for a state display member (LED), and the like are mounted. Yes.

  The box 10 has a sealed structure, that is, a watertight structure. For this purpose, the casing 11 is provided with a seal member 18 as shown in FIG. The seal member 18 is disposed along the peripheral edge of the opening of the housing 11 at a portion where the inner surface of the lid 12 is in close contact when the lid 12 is disposed so as to cover the opening of the housing 11. Yes. Then, when the lid body 12 is disposed with respect to the housing 11, the sealing member 18 is in close contact with the inner surface of the lid body 12, so that the lid body 12 covers the opening of the housing 11 in a watertight manner. The watertight structure of the box 10 is configured in such a form.

  Inside the box 10 (housing 11), as shown in FIGS. 4 to 9 and the like, a driven unit 60 including an imaging unit 40 and the like, and a surface parallel to the XY plane A drive mechanism or the like for freely moving within the vehicle is disposed.

  Although details will be described later, the driven unit 60 includes an imaging optical system (41, 42, 45, etc.), its driving mechanism (46, 47, 49, 59, etc.), an imaging unit 43 including an imaging element 43a, and an imaging element. The drive board 43b, the connection wiring part 71 connected to the imaging element driving board 43b, the light source part 44 (see FIG. 7), and the electricity electrically connected to the imaging element driving board 43b via the connection wiring part 71. An imaging unit 40 including a board 62 (see FIG. 8), a wireless LAN board 72 and the like electrically connected to the electrical board 62, and a moving member on which the imaging unit 40 is mounted. And a second table 29Y which is a second moving member. The detailed configuration of the driven unit 60 and the imaging unit 40 will be described later with reference to FIGS.

  Inside the box 10 (housing 11), the drive mechanism for moving the driven unit 60 in a plane parallel to the XY plane is a first guide rail 30X (first guide portion, first guide). Means), a second guide rail 30Y (second guide portion, second guide means), a first table 29X (first moving member), a second table 29Y (second moving member), The first drive motor 21X, the second drive motor 21Y, the transmission mechanism 35, the first drive force transmission means 36, the second drive force transmission means 37, and the first position detection means (31X, 32X) ) And second position detecting means (31Y, 32Y), first position restricting means 33X, second position restricting means 33Y, and the like.

  The first guide rail 30X is disposed so as to extend along the X-axis direction that is the first direction, and is a first guide portion that guides the movement of the first table 29X in the X-axis direction. It is a guide means. A plurality of first guide rails 30 </ b> X are provided inside the housing 11. In the present embodiment, an example in which two first guide rails 30X are provided is shown. In this case, one of the two first guide rails 30X is provided in a predetermined range along the side wall 11a at a position adjacent to the side wall 11a. The other of the two first guide rails 30X is provided in a predetermined range along the side wall 11b at a position adjacent to the side wall 11b.

  As will be described later, a first drive motor 21X is provided along the side wall 11a at a position adjacent to the side wall 11a in the housing 11. Similarly, a second drive motor 21Y is provided along the side wall 11b at a position adjacent to the side wall 11b in the housing 11. Therefore, the two first guide rails 30X are adjacent positions of the side walls 11a and 11b other than the adjacent positions of the side walls 11a and 11b where the first drive motor 21X and the second drive motor 21Y are disposed. Is provided. Thus, the first drive motor 21X and the first guide rail 30X are arranged side by side so that the major axis directions thereof are linear and along the side wall 11a. Similarly, the second drive motor 21Y and the other first guide rail 30X are arranged side by side so that the major axis directions thereof are linear and along the side wall 11b.

  The first table 29X is a first moving member that is guided by the first guide rail 30X and moves in the X-axis direction along the first guide rail 30X. The first table 29X is driven by a rotational driving force of a first drive motor 21X described later. For this purpose, as shown in FIG. 9, first rail holding portions 29 </ b> Xa that slidably hold the first guide rails 30 </ b> X are provided on the lower surfaces of both ends in the Y-axis direction of the first table 29 </ b> X. Yes. The first rail holding portion 29Xa is disposed so as to extend in the X-axis direction. And the said 1st rail holding | maintenance part 29Xa has a groove-shaped part of the form which can hold the width direction (direction orthogonal to an axial direction) of the 1st guide rail 30X. With such a configuration, the first table 29X is guided by the first guide rail 30X and is configured to move only in the X-axis direction, which is a direction along the first guide rail 30X.

  The second guide rail 30Y is disposed so as to extend along a second direction (Y-axis direction) perpendicular to the X-axis direction, and guides the movement of the second table 29Y in the Y-axis direction. And a second guide means. A plurality of second guide rails 30 </ b> Y are provided in the form of being placed on the first table 29 </ b> X inside the housing 11. In the present embodiment, an example in which two second guide rails 30Y are provided is shown. In this case, the two second guide rails 30Y are arranged side by side at a predetermined interval in the X-axis direction on the first table 29X.

  The second table 29Y is a second moving member that is guided by the second guide rail 30Y and moves in the Y-axis direction along the second guide rail 30Y. Further, the second table 29Y is configured to move in the X axis direction together with the first table 29X. For this purpose, as shown in FIG. 8, a second rail holding portion 29Ya is provided on the lower surface side of the second table 29Y to hold the two second guide rails 30Y slidably. The second rail holding portion 29Ya is disposed so as to extend in the Y-axis direction. And the said 2nd rail holding | maintenance part 29Ya has a groove-shaped part of the form which can hold the width direction (direction orthogonal to an axial direction) of the 2nd guide rail 30Y. With such a configuration, the second table 29Y is guided by the second guide rail 30Y and moves in the Y-axis direction along the second guide rail 30Y, and the first table 29X is moved by the first guide rail 30X. When guided and moved in the X-axis direction along the first guide rail 30X, it moves in the same direction (X-axis direction) together with the first table 29X.

  As described above, the imaging unit 40 including the imaging unit 43 is mounted on the second table 29Y. Thus, the second table 29Y functions as a part of the driven unit 60.

  The first drive motor 21X is a drive motor having a first rotation shaft 21Xa (see FIG. 5) that outputs a rotational force for driving the first table 29X in the X-axis direction. As described above, the first drive motor 21X is provided adjacent to the first side wall 11a of the box 10 (housing 11). In this case, the first rotating shaft 21Xa is disposed in parallel with the first guide rail 30X. The rotational driving force output from the first rotating shaft 21Xa of the first driving motor 21X is transmitted to the first table 29X via the first driving force transmitting means 36, and the first table 29X. Are moved in the X-axis direction.

  The first driving force transmission means 36 is a driving force transmission mechanism that transmits the rotational output from the first driving motor 21X to the first table 29X (first moving member). The first driving force transmission means 36 is constituted by a first speed reduction means 22X, a feed screw 23X, and a feed nut 24X.

  The first decelerating means 22X is a structural unit having therein a gear train or the like that decelerates by receiving the rotational output from the first rotating shaft 21Xa of the first drive motor 21X. The configuration itself of the first speed reduction means 22X is the same as that of a conventionally known power reduction means, and detailed description thereof is omitted.

  The feed screw 23X is a rod-shaped member that rotates in response to the rotational output from the first reduction means 22X. The base end of the feed screw 23X is connected to the first reduction means 22X. The other end of the feed screw 23X is pivotally supported while allowing rotation with respect to a fixed portion of the inner wall surface of the housing 11.

  The feed nut 24X is a component that includes a nut portion that is screwed into the feed screw 23X and is fixed to the first table 29X. With this configuration, when the feed screw 23X rotates upon receiving the rotation output of the first drive motor 21X, the feed nut 24X moves in the direction along the X axis by the action of the nut portion screwed into the feed screw 23X. . At the same time, the first table 29X moves in the same direction. In this case, it is possible to control the rotation direction of the feed nut 24X by controlling the rotation direction of the first drive motor 21X, and thereby to control the advance / retreat direction in the direction along the X axis of the first table 29X. it can.

  That is, the first table 29X is parallel to the first rotation shaft 21Xa of the first drive motor 21X by a feed screw drive system using the first drive motor 21X, the feed screw 23X, the feed nut 24X, and the like ( Move in the X-axis direction).

  The second drive motor 21Y is a drive motor having a second rotation shaft 22Ya (see FIG. 7) that outputs a rotational force for driving the second table 29Y by moving it in the Y-axis direction. The second drive motor 21Y is provided adjacent to the second side wall 11b facing the first side wall 11a of the box 10 (housing 11). In this case, the second rotation shaft 22Ya is disposed so as to be parallel to the first guide rail 30X and the first rotation shaft 21Xa.

  The rotational driving force output from the second rotating shaft 21Ya of the second driving motor 21Y is mounted with the imaging unit 40 including the imaging unit 43 via the second driving force transmission means 37 and the transmission mechanism 35. Is transmitted to the second table 29Y, and this (second table 29Y) is moved in the Y-axis direction.

  In other words, the second table 29Y moves in the Y-axis direction via the transmission mechanism 35 included in the second driving force transmission means 37 that transmits the rotational force from the second driving motor 21Y.

  The second driving force transmission means 37 is a driving force transmission mechanism that transmits the rotation output from the second driving motor 21Y to the second table 29Y (second moving member) on which the imaging unit 43 is mounted. The second driving force transmission means 37 includes a second speed reduction means 22Y, a driving belt 23Y, a plurality of pulleys 24Y and 25Y, and a transmission mechanism 35.

  The second speed reduction means 22Y is a structural unit having a gear train or the like that receives a rotational output from the second rotation shaft 21Ya of the second drive motor 21Y and decelerates therein, and is substantially the same as the first speed reduction means 22X. It is a component unit. Therefore, the second reduction means 22Y also has the same configuration as that of a conventionally known power reduction means, and a detailed description thereof will be omitted.

  The drive belt 23Y and the plurality of pulleys 24Y and 25Y are components that receive the rotational output from the second reduction means 22Y and convert it into a movement output in the Y-axis direction. Of the plurality of pulleys 24Y and 25Y, the pulley 24Y is coaxially fixed to the shaft member that outputs the rotation output from the second reduction means 22Y. A drive belt 23Y is stretched around each pulley 24Y, 25Y, guides the movement of the drive belt 23Y that moves by receiving the rotational output of the second drive motor 21Y, and positions the drive belt 23Y. ing. Since the mechanism for converting the rotational output of the drive motor by the drive belt is well known in the art, further detailed description is omitted.

  A part of the transmission mechanism 35 is fixedly disposed at a predetermined portion of the drive belt 23Y. With this configuration, when the drive belt 23Y moves in the direction along the Y axis in response to the rotational output of the second drive motor 21Y, the transmission mechanism 35 also moves in the same direction. In this case, by controlling the rotation direction of the second drive motor 21Y, the feed direction of the drive belt 23Y and the advance / retreat direction in the direction along the Y axis of the transmission mechanism 35 can be controlled.

  That is, the transmission mechanism 35 moves in a direction (Y-axis direction) orthogonal to the second rotation shaft 21Ya of the second drive motor 21Y by a belt drive system using the second drive motor 21Y and the drive belt 23Y. To do.

  The transmission mechanism 35 includes a third guide rail 28Y (third guide portion, third guide means), a third moving member including a belt holding portion 26Y and a third table 27Y, and a connecting member 39. Is done.

  The third guide rail 28Y is arranged in parallel with the second guide rail 30Y, and is a third guide portion that guides the movement of the third moving member (26Y, 27Y) in the Y-axis direction, and is a third guide means. It is.

  The third moving member is a moving member that receives the rotational force from the second drive motor 21Y and moves in the Y-axis direction along the third guide rail 28Y. The third moving member includes a belt holding portion 26Y and a third table 27Y. The belt holding portion 26Y is a structural member that is fixed to a predetermined portion (a fixed portion indicated by reference numeral 26Ya in FIG. 4) of the drive belt 23Y. The third table 27Y is a moving member that is guided by the third guide rail 28Y and moves in the Y-axis direction along the third guide rail 28Y. For this purpose, as shown in FIG. 8, a third rail holding portion 27Ya is provided on the lower surface side of the third table 27Y to hold the third guide rail 28Y in a slidable manner. The third rail holding portion 27Ya is disposed so as to extend in the Y-axis direction. And the said 3rd rail holding | maintenance part 27Ya has a groove-shaped part of the form which can hold the width direction (direction orthogonal to an axial direction) of the 3rd guide rail 28Y. With such a configuration, the third table 27Y is guided by the third guide rail 28Y and moves in the Y-axis direction along the third guide rail 28Y.

  The belt holding portion 26Y is fixed to the third table 27Y. As described above, the belt holding portion 26Y is fixed at the fixing portion 26Ya of the drive belt 23Y. Therefore, with this configuration, when the drive belt 23Y receives the rotational output of the second drive motor 21Y and moves in the direction along the Y axis, the third table 27Y also moves in the same direction.

  The connecting member 39 is a member that connects the third table 27Y of the third moving member and the second table 29Y on which the imaging unit 40 including the imaging unit 43 is mounted. One end of the connecting member 39 is fixed to the third table 27Y, and the second table 29Y is held at the other end of the connecting member 39 so as to be movable in the X-axis direction (see FIG. 6 and the like).

  Thus, since the third moving member (the third table 27Y) and the second table 29Y are connected by the connecting member 39, the third moving member 21Y is based on the output from the second drive motor 21Y. When the moving member (26Y, 27Y) moves along the third guide rail 28Y, the second table 29Y moves in the Y-axis direction along the third guide rail 28Y of the third moving member (26Y, 27Y). In conjunction with the movement, the Y-axis direction moves along the second guide rail 30Y.

  The first position detection means is a component provided to detect both end positions of the movement range of the first table 29X in the X-axis direction and to control the movement range of the first table 29X in the X-axis direction. The first position detection means is constituted by a pair of first position detection sensors 31X and a first light shielding blade 32X. The pair of first position detection sensors 31X are disposed on the inner wall surface of the second side wall 11b at a predetermined interval in the X-axis direction. In the present embodiment, an example is shown in which a detection element such as a so-called transmissive photo interrupter is applied as the pair of first position detection sensors 31X. The first light shielding blade 32X is disposed on the first table 29X. In this case, the first light shielding blade 32X is disposed at a position corresponding to each of the pair of first position detection sensors 31X when the first table 29X moves in the X-axis direction (FIG. 4 and the like). reference).

  The first position restricting means 33X is a member provided for restricting movement of the first table 29X in the X-axis direction to be within a predetermined range. The first position regulating means 33X is provided at a position where the first table 29X contacts when the first table 29X moves in the X-axis direction. That is, the first table 29X is provided at two locations, a position where the first table 29X contacts when moving in one direction in the X-axis direction and a position where the first table 29X contacts when moving in the other direction. Thereby, the movement range in the X-axis direction of the first table 29X is restricted. In the present embodiment, as a specific form of the first position restricting means 33X, for example, a protruding member that protrudes from the bottom surface of the housing 11 toward the inside (that is, upward) of the housing 11 is provided. An example is shown (see FIG. 4 etc.).

  The second position detection means is a component provided to detect both end positions of the movement range of the third table 27Y in the Y-axis direction and to control the movement range of the third table 27Y in the Y-axis direction. This second position detection means is constituted by a pair of second position detection sensors 31Y and a second light shielding blade 32Y. The pair of second position detection sensors 31Y are arranged on the bottom surface of the housing 11 at a predetermined interval in the Y-axis direction along the third guide rail 28Y at a position near the third guide rail 28Y. In the present embodiment, an example is shown in which a detection element such as a so-called transmissive photo interrupter is applied as the pair of second position detection sensors 31Y. The second light shielding blade 32Y is disposed on the third table 27Y. In this case, the second light shielding blade 32Y is disposed at a position corresponding to each of the pair of second position detection sensors 31Y when the third table 27Y moves in the Y-axis direction (FIG. 4 and the like). reference).

  The second position restricting means 33Y is a member provided for restricting the movement of the third table 27Y in the Y-axis direction to be within a predetermined range. The second position restricting means 33Y is provided at a position where the third table 27Y contacts when the third table 27Y moves in the Y-axis direction. That is, the third table 27Y is provided at two locations, a position where the third table 27Y contacts when moving in one direction and a position where the third table 27Y contacts when moving in the other direction. Thereby, the movement range of the 3rd table 27Y of the Y-axis direction is controlled. In the present embodiment, as a specific form of the second position regulating means 33Y, for example, a protruding member that protrudes from the bottom surface of the housing 11 toward the inside (that is, the upper side) of the housing 11 is provided. An example is shown (see FIG. 4 etc.).

  Next, the detailed configuration of the driven unit 60 will be described below with reference to FIGS.

  As described above, the driven unit 60 includes the imaging unit 40 and the second table 29Y that is a second moving member on which the imaging unit 40 is mounted.

  The imaging unit 40 includes a prism 41 (optical element), a moving optical system (42, 45) including an imaging unit 43, driving means (46 to 52, 59) that are driving mechanisms thereof, a light source unit 44, and imaging. Wireless transmission / reception that performs signal transmission / reception between the drive control system of the element 43a (imaging element drive board 43b), the image processing system of the imaging signal output from the imaging element 43a (electrical board 62, connection wiring unit 71), and an external device. System (wireless LAN board 72, signal wiring section 73) and the like.

  The prism 41 is an optical element having a reflecting surface 41 a that reflects light transmitted through the sample in the incubator 13. That is, the prism 41 in the present embodiment receives light transmitted through the sample in the incubator 13 placed on a predetermined portion (light transmission portion 12a) on the lid body 12 of the box body 10, and changes its optical path. It has a function of being bent at an angle of 90 degrees and reflecting toward a predetermined direction, that is, a light receiving surface (not shown) of the image sensor 43a. The prism 41 has a function of only reflecting light, and a member that does not refraction light, that is, a member that does not have a lens effect is applied. The prism 41 is fixed on the second table 29Y.

  In the present embodiment, an example of using a prism is given as a form of the optical element having the reflection surface. However, besides this form, for example, a configuration example in which a reflection mirror is applied can be considered.

  The moving optical system (42, 45, 43) is configured to be movable in the direction along the optical axis O so that the light from the prism 41 (optical element) forms an image on the light receiving surface of the image sensor 43a. It is. In the present embodiment, the optical axis O of the moving optical system is arranged so as to be along the X axis. Therefore, the moving optical system is configured to move forward and backward in the X-axis direction.

  The moving optical system includes an optical unit integrally configured with a plurality of optical lenses 42 and a plurality of lens holding members 45 that hold the plurality of optical lenses 42, and an imaging unit 43 including an imaging element 43a and the like. This is a unit configured integrally.

  A component constituted by the prism 41, the plurality of optical lenses 42, and the plurality of lens holding members 45 is referred to as an imaging optical system. The imaging optical system constituted by the prism 41 (optical element) and the moving optical system forms a telecentric optical system as a whole.

  The moving optical system (42, 45, 43) is disposed on the second table 29Y so as to be movable in the X-axis direction. For this purpose, a plurality (two in this embodiment) of focus rails 51 as guide means for guiding the movement of the moving optical system in the X-axis direction are provided on the second table 29Y. The focus rail 51 is disposed on the second table 29Y so as to extend along the X-axis direction.

  Correspondingly, the moving optical system is held by a moving optical system holding part 59 having a focus rail holding part 59a that holds the focus rail 51 slidably (see FIGS. 9 and 14).

  The moving optical system holding unit 59 is a constituent member that constitutes a part of a driving mechanism (details will be described later) of the moving optical system. On the lower surface side of the moving optical system holding part 59, the focus rail holding part 59a is fixedly arranged. The focus rail holding portion 59a is formed to have a groove-shaped portion that can hold the width direction of the focus rail 51 (the direction orthogonal to the axial direction). Two focus rail holding portions 59 a are provided corresponding to the two focus rails 51. With such a configuration, the moving optical system is guided by the focus rail 51 and moves only in the X-axis direction along the focus rail 51. In that case, the moving optical system is driven by a rotational driving force of a focus driving motor 46 described later.

  The driving mechanism of the moving optical system is a driving means for moving the entire moving optical system (42, 45) along the optical axis O of the moving optical system.

  The drive mechanism for the moving optical system includes a focus drive motor 46, a focus reduction mechanism 47, a focus rotation output shaft 48, a focus nut 49, a biasing spring 51, a moving optical system holding portion 59, and the like. .

  The focus drive motor 46 is a drive source for moving the moving optical system forward and backward in the X-axis direction. The focus drive motor 46 is fixed on the second table 29Y as a support member. In that case, the rotation axis (not shown) of the focus drive motor 46 is arranged in the direction along the X axis.

  The focus decelerating mechanism 47 is a constituent unit having a gear train or the like that decelerates in response to a rotation output from the rotation shaft of the focus drive motor 46. The configuration itself of the focus reduction mechanism 47 is the same as that of conventionally known power reduction means, and detailed description thereof is omitted. The focus reduction mechanism 47 is also fixed on the second table 29Y as a support member.

  The focus rotation output shaft 48 is a rotation shaft that outputs the rotational force from the focus reduction mechanism 47, and is formed in a feed screw shape, for example. The focus rotation output shaft 48 connects between the focus reduction mechanism 47 and a focus nut 49 described later, and serves to transmit the rotational drive force of the focus drive motor 46 to the focus nut 49.

  The focus nut 49 is a driven member that moves forward and backward in the X-axis direction by the rotation output of the focus drive motor 46. The focus nut 49 includes a nut portion that is screwed to the feed screw-shaped focus rotation output shaft 48 and is fixed on the second table 29Y. The focus nut 49 is provided so as to be movable in the X-axis direction with respect to the second table 29Y as a support member.

  With this structure, when the rotation output of the focus drive motor 46 is received and the focus rotation output shaft 48 (feed screw) rotates, the focus nut 49 is moved by the action of the nut portion screwed to the focus rotation output shaft 48. , Move in the direction along the X axis. Here, the focus nut 49 (driven member) is integrally coupled to the moving optical system holding part 59 (holding part). Accordingly, when the focus nut 49 moves in the direction along the X axis, the moving optical system holding unit 59 (holding unit) simultaneously moves in the same direction. Therefore, the moving optical system integrally held by the moving optical system holding unit 59 (holding unit) also moves in the same direction. In this case, by controlling the rotation direction of the focus drive motor 46, the rotation direction of the nut portion of the focus nut 49 can be controlled, thereby controlling the advance / retreat direction in the direction along the X axis of the moving optical system. it can.

  With such a configuration, the driving mechanism as the driving means adjusts the focal position by appropriately moving the moving optical system in the X axis direction, that is, the direction along the optical axis O, and adjusts the moving optical system to the optical axis. When moving in the direction along the O (X-axis direction), the angle of view of the moving optical system is configured to be constant. For this purpose, a telecentric optical system is employed as a whole for the imaging optical system in the sample observation apparatus 1 of the present embodiment including the prism 41 and the moving optical system.

  The biasing spring 51 is a biasing member that biases the focus nut 49 in one direction with respect to the second table 29Y (fixed portion). One end of the biasing spring 51 is fixed to the focus nut 49, and the other end is fixed to the fixing portion of the second table 29Y. For this purpose, the focus nut 49 is provided with a spring locking shaft 50 that fixes one end of the biasing spring 51. A support shaft 52 that fixes the other end of the urging spring 51 is implanted in the fixed portion on the second table 29Y. As the biasing spring 51 in the present embodiment, an example in which, for example, a coiled coil spring or the like is applied is shown.

  The light source unit 44 is disposed around the prism 41 on the second table 29Y. In the present embodiment, an example in which three light source portions 44 are arranged around the prism 41 is shown. The light source unit 44 is a light source member that emits illumination light from the lower side to the upper side of the sample in the incubator 13 placed on a predetermined portion (light transmission unit 12a) on the lid body 12. As the light source unit 44, for example, a light emitter such as an LED (light emitting diode) is applied.

  A light diffusion plate 53 is disposed above the light source unit 44, that is, between the light source unit 44 and the light transmission unit 12 a of the lid body 12. The light diffusing plate 53 is formed of, for example, a milky white resin thin plate having light permeability and light diffusing properties. The light diffusing plate 53 serves to illuminate the inside of the incubator 13 through the light transmitting portion 12a by diffusing the illumination light emitted from the light source portion 44.

  The illumination light emitted from the light source unit 44 passes through the light transmitting unit 12a and the transparent bottom surface of the incubator 13 and enters the incubator 13 as indicated by an arrow L in FIG. The illumination light that has entered the incubator 13 is reflected by the reflecting surface 13a in the incubator 13, and then passes through the sample existing in the culture medium 200 in the incubator 13, and passes through the light transmitting portion 12a. It is configured to enter the prism 41.

  The image sensor 43a employs a CMOS image sensor in the present embodiment. Further, an image sensor drive substrate 43b (first image control circuit board) for controlling the drive of the image sensor 43a is disposed in the vicinity of the image sensor 43a.

  The image sensor driving substrate 43b has a drive unit such as a timing generator (TG) that inputs a predetermined clock and a synchronization signal and generates various timing signals for driving the image sensor 43a.

  In addition, the image sensor driving substrate 43b includes an analog front end circuit including a correlated double sampling circuit (CDS) that performs noise reduction on an output signal from the light receiving unit (PD) of the image sensor 43a, an AD converter, and the like. (AFE) may be provided.

  Furthermore, the image sensor driving substrate 43b may be formed integrally with the image capturing unit 43 including the image sensor 43a.

  In the present embodiment, the CMOS image sensor is employed as the image sensor. However, the present invention is not limited thereto, and another solid-state image sensor such as a CCD image sensor may be employed.

  A connection wiring portion 71 is connected to the imaging element driving substrate 43 b, and the imaging element driving substrate 43 b is electrically connected to the electric substrate 62 via the connection wiring portion 71. That is, the above-described clock signal, synchronization signal, and imaging signal are transmitted via the connection wiring portion 71.

  As described above, the connection wiring portion 71 constitutes the imaging unit 40, and includes the imaging element drive board 43b (first imaging control circuit board) and the electric board 62 (second imaging control circuit board). It is a wiring part connected by the shortest path.

  The connection wiring portion 71 is disposed so as to move integrally with the movement of the second table 29Y, and electrically connects the above-described image sensor driving substrate 43b and the electric substrate 62.

  Since the connection wiring part 71 is disposed as described above, the clock signal, the synchronization signal, and the imaging signal to be transmitted are also wired by the shortest path. At least the conventional type, that is, the type that transmits the imaging signal to the outside from the second table 29Y that is the second moving member (for example, the type that transmits the imaging signal to the flexible wiring cable 61 in the present embodiment). In contrast, since it is not necessary to transmit a high-frequency signal such as an imaging signal over a long distance, it is a very advantageous condition in terms of resistance to external noise.

  The electric board 62 is connected to the electric board 55 via the flexible wiring cable 61, while being electrically connected to the image sensor driving board 43 b via the connection wiring portion 71.

  As described above, the electric board 62 constitutes the imaging unit 40 and is mounted on the second table 29Y as the second moving member. Specifically, for example, in the vicinity where the light source unit 44 is disposed, the electric board 62 is fixedly disposed on the lower surface side of the second table 29Y, that is, the surface opposite to the side where the light source unit 44 is provided. .

  A plurality of electric members 62a and the like are disposed on the electric board 62, and in addition to the driving circuit for the light source unit 44 and the driving mechanism for the driving mechanism of the moving optical system, the imaging signal output from the imaging element 43a An image processing circuit and the like are mounted.

  The electric board 62 can receive a predetermined power supply from an external device via the flexible wiring cable 61 (and the electric board connector 16). Further, predetermined data or signals can be exchanged with an external device via the flexible wiring cable 61 (and the electric board 55 and the connector 17).

  However, the present invention transmits an imaging signal from the electric board 62 (in other words, from the second table 29Y as the second moving member) to the outside without using a wire such as the flexible wiring cable 61 or the like. It is characterized by that. This effect will be described in detail later.

  The flexible wiring cable 61 extends from the driven unit 60 that is a moving member that moves in the XY plane. For this purpose, the flexible wiring cable 61 is set to have a length so as to be able to absorb the movement in the XY plane.

  The electric board 62 includes a clock signal (CLK) for driving the image sensor 43a, a clock for generating a synchronization signal (vertical synchronization signal VD, horizontal synchronization signal HD), and a synchronization signal generation unit. These signals are supplied to the image sensor driving substrate 43b via the.

  Further, the electric board 62 is provided with an image processing circuit that performs predetermined image processing on the image pickup signal output from the image pickup element driving board 43b. The image processing circuit may be realized by a PLD (Programmable Logic Device) configured by a so-called FPGA (field-programmable gate array) or the like.

  In addition, a removable storage medium such as a memory card (not shown) can be mounted on the electric board 62, and the acquired image data and accompanying various information data can be recorded.

  In other words, the image signal from the image sensor 43a output from the image sensor drive substrate 43b is subjected to predetermined image processing on the electric substrate 62, and then the second table which is a second moving member on the metal wire or the like. It is possible to transmit to the outside by taking out the memory card without performing wired transmission from 29Y to the subsequent stage.

  In the present embodiment, the clock signal and the synchronization signal described above are provided with the generating unit inside the electric board 62, but the present invention is not limited thereto, and is supplied from the outside via the flexible wiring cable 61. It may be a thing.

  In the present embodiment, the power supply for the electric board 62 is supplied from an external device. However, the present invention is not limited to this, and a power supply may be provided inside the housing 10. A power source may be provided.

  Further, the electric board 62 may include a power supply circuit including a battery for driving the focus driving motor 46.

  Further, connecting wires 63, lead wires 64 (see FIG. 11) and the like extend from the electric board 62, and ends of these lead wires, flexible printed circuit boards, etc. are connected to the light source section 44 and the driving mechanism (the focus of the driving mechanism). It is connected to a drive motor 46) and the like.

  In the present embodiment, a wireless LAN board 72 for transmitting / receiving signals to / from an external device is further provided. The wireless LAN board 72 constitutes the imaging unit 40 and is mounted on the second table 29Y, which is the second moving member, like the electric board 62.

  The wireless LAN board 72 is electrically connected to a predetermined circuit section on the electric board 62 via a signal wiring section 73, and can transmit the acquired image data to an external device wirelessly. Note that the wireless LAN system employed in the present embodiment may be one that is generally put into practical use and widely used, and therefore the detailed description of the configuration is omitted.

  As described above, when the function of the wireless LAN board 72 is used, the image pickup signal from the image pickup element 43a output from the image pickup element driving board 43b is transferred to the subsequent stage from the second table 29Y which is the second moving member on the metal wire or the like. It is possible to transmit directly to the outside by wireless without performing wired transmission.

  In the present embodiment, the wireless LAN board 72 is separate from the electric board 62. However, the present invention is not limited to this, and the electric board 62 may be provided with a circuit having the function of the wireless LAN board 72. .

  Each of the light source unit 44, the prism 41 (optical element), and the moving optical system holding unit 59 (holding unit) is disposed so as to have a predetermined interval. Here, as the predetermined interval, an interval indicated by a symbol D in FIG. 13 is defined. This interval D is a moving range necessary for the moving optical system to move for focus adjustment.

  As described above, the light source unit 44, the prism 41 (optical element), and the drive mechanism including the focus drive motor 46 and the like are fixedly arranged on the second table 29Y. At the same time, a focus rail 51 is disposed on the second table 29Y, and the focus rail 51 is slidably held by the focus rail holding portion 59a of the moving optical system holding portion 59. Therefore, with such a configuration, the second table 29Y functions as a support member that supports the movable optical system holding unit 59 (the movable optical system held by the movable table 59) so as to be movable in the X-axis direction.

  As described above, in the present embodiment, image processing related to the imaging signal from the imaging device driving board 43b is performed on the electric board 62, and the imaging signal that has undergone this image processing is attached to the removable memory card or the wireless LAN board 72. By using the function, since it can be transmitted to the outside from the second table 29Y as the second moving member without going through wired transmission such as a metal wire, it is a conventional type, that is, the second moving member. Unlike the type in which the imaging signal is transmitted from the second table 29Y to the outside (for example, the type in which the imaging signal is transmitted using the flexible wiring cable 61 in the present embodiment), the high-frequency signal such as the imaging signal is extended over a long distance. It is not necessary to transmit the data over a long period, which is a very advantageous condition in terms of resistance to external noise.

  Further, a connection wiring portion that connects the path from the image sensor driving substrate 43b to the electric substrate 62 (that is, the image sensor driving substrate 43b (first imaging control circuit substrate) and the electric substrate 62 (second imaging control circuit substrate). 71), first, the image sensor driving substrate 43b and the electric substrate 62 are arranged on the second table 29Y which is the same second moving member, and the image sensor driving substrate 43b and the electric substrate 62 are arranged. Are connected to the same second table 29Y by the connection wiring portion 71 that moves integrally, the image sensor drive substrate 43b and the electric substrate 62 can be connected by the shortest path, and the influence of noise resistance is minimized. Can be stopped.

  Summing up these effects, the present embodiment can shorten the transmission path of high-frequency signals such as imaging signals and improve the resistance to external noise, thereby enabling higher image quality. In addition, an excessive noise countermeasure is not required, which is advantageous in terms of cost and further contributes to downsizing.

  Note that the present invention is not limited to the above-described embodiment, and various modifications and applications can of course be implemented without departing from the spirit of the invention. Further, the above embodiments include inventions at various stages, and various inventions can be extracted by appropriately combining a plurality of disclosed constituent elements. For example, even if several constituent requirements are deleted from all the constituent requirements shown in the above-described embodiment, if the problem to be solved by the invention can be solved and the effect of the invention can be obtained, this constituent requirement is deleted. The configured structure can be extracted as an invention. Furthermore, constituent elements over different embodiments may be appropriately combined. The invention is not limited by the specific embodiments thereof, except as limited by the appended claims.

DESCRIPTION OF SYMBOLS 1 ... Sample observation apparatus 10 ... Box 11 ... Housing 11a ... 1st side wall 11b ... 2nd side wall 12 ... Cover 12a ... Light transmission part 13 ... Incubator 13a ... Reflection Surface 14 …… Operation member 15 …… Status display portions 16, 17 …… Connector 18 …… Seal member 21X …… First drive motor 21Xa …… First rotating shaft 21Y …… Second drive motor 21Ya… ... 2nd rotating shaft 22X ... 1st deceleration means 22Y ... 2nd deceleration means 22Ya ... 2nd rotating shaft 23Y ... Drive belt 24X ... Feed nut 24Y, 25Y ... Pulley 26Y ... Belt holding part 26Ya …… Fixed portion 27Y …… Third table 27Ya …… Third rail holder 28Y …… Third guide rail 29X …… First table 29Xa …… First rail holder 29Y …… Second table 29Ya …… Second 2-rail maintenance Part 30X... First guide rail 30Y... Second guide rail 31X... First position detection sensor 31Y... Second position detection sensor 32X. Position restricting means 33Y ... second position restricting means 35 ... transmitting mechanism 36 ... first driving force transmitting means 37 ... second driving force transmitting means 39 ... connecting member 40 ... imaging unit 41 ... prism 41a …… Reflective surface 42 …… Optical lens 43 …… Image pickup portion 43a …… Image pickup device 43b …… Image pickup device drive substrate 44 …… Light source portion 45 …… Lens holding member 46 …… Focus drive motor 47 …… Focus deceleration mechanism 48... Focus rotation output shaft 49... Focus nut 50... Spring locking shaft 51... Focus rail 52... Support shaft 53. Moving the optical system holding portion 59a ...... focus rail holding portion 60 ...... driven unit 61 ...... flexible wire cable,
63 ... connection line 62 ... electric board 62a ... electric member 64 ... lead wire 71 ... connection wiring part 72 ... wireless LAN board 100 ... sample observation system 101 ... thermostat 102 ... control device 103 ... ... Input device 104 ... Display device 200 ... Medium

Claims (5)

A sealed box,
A first moving member that moves in a first direction along the first guide in the box;
The first moving member moves in the first direction together with the first moving member, and after moving, the second moving portion moves in the second direction perpendicular to the first direction along the second guide portion with respect to the first moving member. Two moving members;
An imaging optical system disposed on the second moving member and extending in the first direction;
An image sensor that is disposed on the second moving member and converts subject light that has passed through the imaging optical system into an electrical signal;
A first imaging control circuit board disposed on the second moving member for driving and controlling the imaging element;
A second imaging control circuit board that is disposed on the second moving member and is electrically connected to the first imaging control circuit board and that processes a signal from the first imaging control circuit;
Comprising
The first imaging control circuit board is disposed around the imaging element,
The sample observation apparatus, wherein the second imaging control circuit board is disposed on the lower side in the optical axis direction of the first lens that is a subject incident portion of the imaging optical system. The sample observation apparatus according to claim 1, further comprising: a memory that is detachably disposed on the second imaging control circuit board and that can store an imaging signal output from the imaging element. The communication device according to claim 1, further comprising a communication unit that is arranged to move together with the movement of the second moving member and communicates an imaging signal output from the imaging element to the outside of the box. The sample observation apparatus described.   The sample observation apparatus according to claim 3, wherein the communication unit is provided on the second imaging control circuit board.   A connection wiring portion is provided to move integrally with the second moving member, and electrically connects the first imaging control circuit board and the second imaging control circuit board. The sample observation apparatus according to claim 1.

Images