JP2017073161A5 - - Google Patents

Download PDF

Info

Publication number
JP2017073161A5
JP2017073161A5 JP2016240283A JP2016240283A JP2017073161A5 JP 2017073161 A5 JP2017073161 A5 JP 2017073161A5 JP 2016240283 A JP2016240283 A JP 2016240283A JP 2016240283 A JP2016240283 A JP 2016240283A JP 2017073161 A5 JP2017073161 A5 JP 2017073161A5
Authority
JP
Japan
Prior art keywords
activity
direction value
activity measure
value
score
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016240283A
Other languages
English (en)
Japanese (ja)
Other versions
JP6335260B2 (ja
JP2017073161A (ja
Filing date
Publication date
Priority claimed from EP11195417.8A external-priority patent/EP2608122A1/en
Application filed filed Critical
Publication of JP2017073161A publication Critical patent/JP2017073161A/ja
Publication of JP2017073161A5 publication Critical patent/JP2017073161A5/ja
Application granted granted Critical
Publication of JP6335260B2 publication Critical patent/JP6335260B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016240283A 2011-06-10 2016-12-12 ネットワークに基づく生物学的活性評価のためのシステムおよび方法 Active JP6335260B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161495824P 2011-06-10 2011-06-10
US61/495,824 2011-06-10
US201161525700P 2011-08-19 2011-08-19
US61/525,700 2011-08-19
EP11195417.8A EP2608122A1 (en) 2011-12-22 2011-12-22 Systems and methods for quantifying the impact of biological perturbations
EP11195417.8 2011-12-22

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2014514108A Division JP6138768B2 (ja) 2011-06-10 2012-06-11 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018061665A Division JP2018120617A (ja) 2011-06-10 2018-03-28 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Publications (3)

Publication Number Publication Date
JP2017073161A JP2017073161A (ja) 2017-04-13
JP2017073161A5 true JP2017073161A5 (enExample) 2017-07-13
JP6335260B2 JP6335260B2 (ja) 2018-05-30

Family

ID=47295520

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2014514108A Active JP6138768B2 (ja) 2011-06-10 2012-06-11 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2014514106A Active JP6138767B2 (ja) 2011-06-10 2012-06-11 生物学的攪乱の影響を定量化するためのシステムおよび方法
JP2016240280A Active JP6336020B2 (ja) 2011-06-10 2016-12-12 生物学的攪乱の影響を定量化するためのシステムおよび方法
JP2016240283A Active JP6335260B2 (ja) 2011-06-10 2016-12-12 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2018061665A Withdrawn JP2018120617A (ja) 2011-06-10 2018-03-28 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2014514108A Active JP6138768B2 (ja) 2011-06-10 2012-06-11 ネットワークに基づく生物学的活性評価のためのシステムおよび方法
JP2014514106A Active JP6138767B2 (ja) 2011-06-10 2012-06-11 生物学的攪乱の影響を定量化するためのシステムおよび方法
JP2016240280A Active JP6336020B2 (ja) 2011-06-10 2016-12-12 生物学的攪乱の影響を定量化するためのシステムおよび方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018061665A Withdrawn JP2018120617A (ja) 2011-06-10 2018-03-28 ネットワークに基づく生物学的活性評価のためのシステムおよび方法

Country Status (5)

Country Link
US (3) US20140172398A1 (enExample)
EP (3) EP2608122A1 (enExample)
JP (5) JP6138768B2 (enExample)
CN (4) CN103765448B (enExample)
WO (2) WO2012168483A1 (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
US8818920B2 (en) * 2012-03-09 2014-08-26 Bank Of America Corporation Incremental effect modeling by area index maximization
CN110096494B (zh) * 2012-10-22 2024-04-26 起元科技有限公司 使用源跟踪剖析数据
US8554712B1 (en) * 2012-12-17 2013-10-08 Arrapoi, Inc. Simplified method of predicting a time-dependent response of a component of a system to an input into the system
CA2896732A1 (en) * 2012-12-28 2014-07-03 Ty Matthew Thomson Quantitative assessment of biological impact using mechanistic network models
US9253044B1 (en) * 2013-01-04 2016-02-02 Selventa, Inc. Quantitative assessment of biological impact using overlap methods
JP6397894B2 (ja) * 2013-04-23 2018-09-26 フィリップ モリス プロダクツ エス アー 体系毒物学において機構的ネットワークモデルを用いるためのシステムおよび方法
EP3033721A1 (en) * 2013-08-12 2016-06-22 Philip Morris Products S.A. Systems and methods for crowd-verification of biological networks
CN105612524B (zh) * 2013-09-13 2019-04-02 菲利普莫里斯生产公司 评估生物外源性物质代谢扰动的系统和方法
US12020823B2 (en) * 2013-11-01 2024-06-25 H. Lee Moffitt Cancer Center And Research Institute, Inc. Integrated virtual patient framework
US9430739B2 (en) 2013-12-19 2016-08-30 Praedicat, Inc. Determining general causation from processing scientific articles
GB201405243D0 (en) 2014-03-24 2014-05-07 Synthace Ltd System and apparatus 1
SG11201610035RA (en) * 2014-06-30 2017-01-27 Evolving Machine Intelligence Pty Ltd A system and method for modelling system behaviour
US10309956B2 (en) 2014-07-10 2019-06-04 R.J. Reynolds Tobacco Company Process for assessing risk of substance administration
AR101678A1 (es) * 2014-09-11 2017-01-04 Sony Corp Dispositivo de procesamiento de información, método de procesamiento de información y medio de almacenamiento legible por computadora no transitorio de almacenamiento de programa
US20160092653A1 (en) * 2014-09-30 2016-03-31 Koninklijke Philips N.V. NUTRITIONAL INTAKE VIEWER (NutriWeb)
EP3226750A4 (en) * 2014-12-05 2018-07-04 Lifecycle Technologies Pty Ltd Method and system for improving a physiological response
US9762393B2 (en) * 2015-03-19 2017-09-12 Conduent Business Services, Llc One-to-many matching with application to efficient privacy-preserving re-identification
GB201511587D0 (en) * 2015-07-02 2015-08-19 Ge Healthcare Bio Sciences Ab A method and a system for determining a concentration range for a sample by means of a calibration curve
US10529253B2 (en) * 2016-08-30 2020-01-07 Bernard De Bono Method for organizing information and generating images of biological structures as well as related resources and the images and materials so generated
WO2018069891A2 (en) * 2016-10-13 2018-04-19 University Of Florida Research Foundation, Inc. Method and apparatus for improved determination of node influence in a network
US20190362216A1 (en) * 2017-01-27 2019-11-28 Ohuku Llc Method and System for Simulating, Predicting, Interpreting, Comparing, or Visualizing Complex Data
WO2018203349A1 (en) * 2017-05-01 2018-11-08 Parag Kulkarni A system and method for reverse hypothesis machine learning
US20200332364A1 (en) * 2017-05-12 2020-10-22 Laboratory Corporation Of America Holdings Compositions and methods for detection of diseases related to exposure to inhaled carcinogens
US10657179B2 (en) * 2017-09-01 2020-05-19 X Development Llc Bipartite graph structure
US11024403B2 (en) * 2018-01-22 2021-06-01 X Development Llc Method for analyzing and optimizing metabolic networks
US11068540B2 (en) 2018-01-25 2021-07-20 Ab Initio Technology Llc Techniques for integrating validation results in data profiling and related systems and methods
US11309058B2 (en) 2018-03-30 2022-04-19 X Development Llc Modeling the chemical composition of a biological cell wall
CN108614536B (zh) * 2018-06-11 2020-10-27 云南中烟工业有限责任公司 一种卷烟制丝工艺关键因素的复杂网络构建方法
US10961921B2 (en) 2018-09-19 2021-03-30 Pratt & Whitney Canada Corp. Model-based control system and method for a turboprop engine
US11521710B2 (en) * 2018-10-31 2022-12-06 Tempus Labs, Inc. User interface, system, and method for cohort analysis
CN109521172A (zh) * 2018-11-14 2019-03-26 苏州新派特信息科技有限公司 一种采用扁螺防控红丝虫的生物扰动效应的模拟方法
CN109712667A (zh) * 2018-12-28 2019-05-03 广东省心血管病研究所 模拟骨髓间充质干细胞移植体外模型构建中的控制方法
CN113632174B (zh) 2019-01-23 2025-03-25 密歇根大学董事会 用于nmda、甘氨酸和ampa受体的调节剂的药物基因组学决策支持
US10585990B1 (en) 2019-03-15 2020-03-10 Praedicat, Inc. Live updating visualization of causation scores based on scientific article metadata
EP3799057A1 (en) 2019-09-25 2021-03-31 Koninklijke Philips N.V. Prediction tool for patient immune response to a therapy
CN110729022B (zh) * 2019-10-24 2023-06-23 江西中烟工业有限责任公司 一种被动吸烟大鼠早期肝损伤模型建立方法及相关基因筛选方法
CN111223520B (zh) * 2019-11-20 2023-09-12 云南省烟草农业科学研究院 一种预测烟草尼古丁含量的全基因组选择模型及其应用
US10748091B1 (en) 2020-01-16 2020-08-18 Applied Underwriters, Inc. Forecasting digital reservoir controller
CN111755065B (zh) * 2020-06-15 2024-05-17 重庆邮电大学 一种基于虚拟网络映射和云并行计算的蛋白质构象预测加速方法
TWI746381B (zh) 2021-02-25 2021-11-11 長庚醫療財團法人高雄長庚紀念醫院 利用深度學習分析眼振感測資料的方法及眼振感測分析系統
US20250013803A1 (en) * 2021-10-05 2025-01-09 Vishal Gupta A system for entity based stagewise formal specification of processes and a method therefor
US20230260600A1 (en) * 2022-02-16 2023-08-17 Stokely-Van Camp, Inc. High Efficacy Functional Ingredient Blends
CN114821823B (zh) * 2022-04-12 2023-07-25 马上消费金融股份有限公司 图像处理、人脸防伪模型的训练及活体检测方法和装置
JP2023161401A (ja) * 2022-04-25 2023-11-07 国立研究開発法人農業・食品産業技術総合研究機構 形質予測方法、形質予測モデル生成方法、形質予測装置、形質予測モデル生成装置、及び形質予測システム
CN116453585B (zh) * 2023-02-23 2025-08-12 中南大学 mRNA和药物关联的预测方法、装置、终端设备及介质

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5640494A (en) * 1991-03-28 1997-06-17 The University Of Sydney Neural network with training by perturbation
US6132969A (en) * 1998-06-19 2000-10-17 Rosetta Inpharmatics, Inc. Methods for testing biological network models
IL134994A0 (en) * 2000-03-09 2001-05-20 Yeda Res & Dev Coupled two way clustering analysis of data
US7623969B2 (en) * 2002-01-31 2009-11-24 The Institute For Systems Biology Gene discovery for the system assignment of gene function
US20070016390A1 (en) * 2002-03-06 2007-01-18 Bernardo Diego D Systems and methods for reverse engineering models of biological networks
WO2005055113A2 (en) * 2003-11-26 2005-06-16 Genstruct, Inc. System, method and apparatus for causal implication analysis in biological networks
US7376520B2 (en) * 2005-03-16 2008-05-20 Lam Research Corporation System and method for gas flow verification
US20070225956A1 (en) * 2006-03-27 2007-09-27 Dexter Roydon Pratt Causal analysis in complex biological systems
US20080195322A1 (en) * 2007-02-12 2008-08-14 The Board Of Regents Of The University Of Texas System Quantification of the Effects of Perturbations on Biological Samples
US8518649B2 (en) * 2007-04-04 2013-08-27 {hacek over (S)}árka O. Southern Systems and methods for analyzing persistent homeostatic perturbations
US8068994B2 (en) * 2007-07-27 2011-11-29 Wayne State University Method for analyzing biological networks
US20090099784A1 (en) 2007-09-26 2009-04-16 Ladd William M Software assisted methods for probing the biochemical basis of biological states
US20110119259A1 (en) * 2008-04-24 2011-05-19 Trustees Of Boston University Network biology approach for identifying targets for combination therapies
US8577619B2 (en) * 2008-05-27 2013-11-05 Sloan Kettering Institute For Cancer Research Models for combinatorial perturbations of living biological systems
EP2342664A1 (en) * 2008-09-03 2011-07-13 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Computer implemented model of biological networks
US20100299289A1 (en) * 2009-05-20 2010-11-25 The George Washington University System and method for obtaining information about biological networks using a logic based approach
EP2514361A1 (en) * 2011-04-22 2012-10-24 Université Catholique De Louvain In vivo quantification of a variation of oxygenation in a tissue by using a magnetic resonance imaging technique
EP2608122A1 (en) 2011-12-22 2013-06-26 Philip Morris Products S.A. Systems and methods for quantifying the impact of biological perturbations
US20140214336A1 (en) 2011-09-09 2014-07-31 Philip Morris Products S.A. Systems and methods for network-based biological activity assessment
JP6397894B2 (ja) 2013-04-23 2018-09-26 フィリップ モリス プロダクツ エス アー 体系毒物学において機構的ネットワークモデルを用いるためのシステムおよび方法

Similar Documents

Publication Publication Date Title
JP2017073161A5 (enExample)
JP2017073160A5 (enExample)
Pullin et al. A comparison of marker gene selection methods for single-cell RNA sequencing data
US10242087B2 (en) Cluster evaluation in unsupervised learning of continuous data
CN108665120B (zh) 打分模型的建立、用户信用的评估方法及装置
US9830365B1 (en) Determining influence across social networks
US9436907B2 (en) Method and system for calculating value of website visitor
JP2021506541A5 (enExample)
CN110686633A (zh) 一种滑坡位移预测方法、装置及电子设备
US20160125159A1 (en) System for management of health resources
JP2012518834A5 (enExample)
CN116521511A (zh) 风险代码事前检测方法、装置、设备及存储介质
JP2020030111A5 (ja) 異常予兆検出システム
JPWO2021028988A5 (ja) ユーザ位置計算装置及び方法、及びプログラム
JP6919706B2 (ja) 情報処理方法、情報処理装置及び情報処理コンピュータプログラム
US20180075195A1 (en) System and method for facilitating computer-assisted healthcare-related outlier detection
Kahouadji et al. Vibration-based damage assessment in truss structures using local frequency change ratio indicator combined with metaheuristic optimization algorithms
JP6930195B2 (ja) モデル同定装置、予測装置、監視システム、モデル同定方法および予測方法
Delcea et al. GM (1, 1) in bankruptcy forecasting
Moa et al. Flucast: a real-time tool to predict severity of an influenza season
Choudhary et al. Parameter estimation of software reliability model using firefly optimization
JP6728830B2 (ja) 情報処理装置、情報処理方法、及び、プログラム
CN110335678A (zh) 一种高原适应性评估方法及系统
CN112347088A (zh) 一种数据可信度优化方法、存储介质和设备
Çelik Stabilizing heteroscedasticity for butterfly-distributed residuals by the weighting absolute centered external variable