JP2017012628A - Blue led light radiation for softening subcutaneous fatty tissue and dissolving and atrophying or freezing and atrophying followed by atrophy of skin, and freezing treatment tool - Google Patents

Abstract

PROBLEM TO BE SOLVED: To achieve softening and atrophying a subcutaneous fat tissue having high fat absorption selectivity without generation of heat evolution and pain, and inflammation of a skin, and with less load of prevention of slacking of a skin, improve cooling efficiency of a skin surface and reduce treatment time, prevent overheat and prevent generation of heat and pain, and apply to various fat layers by a freezing treatment method to a portion having a thick fat layer, and by blue light radiation to a portion having a thin fat layer.SOLUTION: The means relates to: (1) a blue LED light radiation cooling/freezing treatment tool; (2) a blue light radiation tool for radiating a blue wavelength of 400-480 nm; (3) a pulse light emission; (4) a blue light radiation tool for radiating a blue light which is 1 W or higher per 1 cm2; (5) a freezing function for freezing and atrophying fat cells in a subcutaneous fat component; (6) a gel body having thermal conductivity and light transmissivity; (7) a mechanism for cooling and freezing the gel body; (8) a detachable air type suction cup; and (9) a structure in which the cooling and freezing mechanism is arranged to contact a back face of a light emission body.SELECTED DRAWING: Figure 5

Description

TECHNICAL FIELD The present invention relates to a technique for cosmetic formation in which a high-power blue LED light irradiation refrigerator is contact-irradiated to the skin, and the fat of the subcutaneous adipose tissue is softened, melted and frozen, and the skin is contracted without injury accompanied by an inflammatory reaction. Is.

Non-surgical methods for contracting subcutaneous adipose tissue include ultrasound, radio waves, freezing, and laser. The energy of ultrasonic waves and radio waves is known as a non-invasive constriction device for cooling the skin surface. The laser irradiates the skin surface at a low output with a red wavelength to dissolve and contract the subcutaneous fat tissue. Absorption of red light occurs on the skin surface and generates heat, so it is irradiated with low power to avoid skin burns. At the same output, red light penetrates deeper into the tissue than blue light with a short wavelength. However, the absorption of subcutaneous adipose tissue is higher as the wavelength is shorter in the range from visible light to 1200 nm, and the absorption is specifically higher at wavelengths of 400 to 450 nm. Specific high absorption by adipose tissue is also seen in the infrared region near 1200 nm, but water absorption is high at 1100 nm or more, and fever in the subcutaneous dermis layer cannot be avoided, and there is a risk of thermal injury to the subcutaneous dermis layer. On the other hand, for the same wavelength, the higher the output, the deeper the irradiation depth. It is said that atrophy of adipose tissue by low-power laser and cryotherapy that does not cause pain, heat denaturation, etc. is due to apoptosis (natural death) of subcutaneous fat cells. Light acupuncture treatment is known in which skin contraction is caused by heat contraction of the collagen component of the skin without destruction of the epidermis layer by light in the 600-1200 nm region under cooling of the skin surface. It is also known that light absorption by collagen is even higher at 400-500 nm, shorter than 600 nm.

JP2013-034536 Special table 2013-514125 US6071239 US3941122 US 5964749 A

2009, Lasers in Surgery and Medicine, “Low-level laser therapy as a non-invasive approach for body contouring: A randomized, controlled study”, Robert F. Jackson, Volume 41, Issue 10, pages 799809 2005, Optics and Spectroscopy, “Optical Properties of the Subcutaneous Adipose Tissuein the Spectral Range 400 to 2500 nm”, A. N. Bashkatov, Vol. 99, No. 5, 2005, pp. 836-842 2008, Optics Express, "Measurement of internal tissue optical properties at ultraviolet and visible wavelengths: Development and implementation of a fiberoptic-based system" Quanzeng Wang, Vol. 16, Issue 12, pp. 8685-8703 2009, SPIE Newsroom. “Low-level laser therapy: an emerging clinical paradigm”, Ying-Ying Huang, Biomedical Optics & Medical Imaging 2014, Clinical, Cosmetic and Investigational Dermatology, Nils Krueger, “Cryolipolysis for noninvasive body contouring: clinical efficacy and patient satisfaction”, 201-205

Blue LED light irradiation, the skin surface is cooled by a refrigeration treatment device, without fever pain and skin irritation, while skin atrophy is accompanied by softening of subcutaneous fat tissue by blue LED light irradiation, dissolution atrophy and thick fat layer Depending on the type, it can be used for cosmetic surgery that can be frozen. Blue LED light irradiation with specifically high fat absorption and blue LED light irradiation capable of cooling the skin and a cryotherapy device prevent thermal pain and inflammation of the skin and enable adipose tissue dissolution and contraction. Blue LED light irradiation and refrigeration treatment equipment prevent overheating during blue LED light irradiation and prevent the generation of thermal pain. Blue LED light irradiation and refrigeration treatment equipment will expand the application to thin parts as well as thick parts of fat layers. A large amount of light energy can be input by the blue LED light irradiation and the refrigeration treatment device, and a high contraction efficiency of the adipose tissue is realized. The efficiency of refrigeration of adipose tissue is increased by suctioning the skin in the range of refrigeration treatment using a blue LED light irradiation and refrigeration treatment device. The blue LED light irradiation and the cryotherapy device enable high cooling efficiency and low temperature that can be cryotherapy.

A first invention for solving the problem is blue LED light irradiation having a high output sufficient to soften and dissolve the subcutaneous fat tissue fat component and contract the skin tissue through contact cooling of the skin surface and simultaneously through the contact cooling surface. It is a cooling and freezing treatment device. The second invention is an irradiator for blue light having a wavelength of 400 to 480 nm, which is specifically high in the infrared region within 1200 nm from the visible light region. The third invention is a temperature control mechanism using pulsed light emission that increases the accuracy of temperature control of the irradiated living body. The fourth invention is a blue light irradiator with 1 W or more per square centimeter. A fifth invention is a blue LED light irradiation cooling / freezing function that freezes subcutaneous fat components via a light irradiation contact surface and contracts fat cells. The sixth invention is a thermally conductive and translucent gel that can cool and cool the skin surface below body temperature and can freeze the skin surface to -5 degrees C or below. The seventh invention is a mechanism for cooling and freezing the gel body that is in skin contact with the LED light emitter. The eighth invention is a detachable air suction cup capable of sucking the skin in the range to be cooled and frozen by the blue LED light irradiation cooling / freezing treatment device of claim 1. A ninth aspect of the invention is a structure in which a Peltier cooler is disposed in contact with the back surface of the light emitter in a cooling / freezing mechanism. A tenth aspect of the invention is a structure in which an antifreeze circulating cooling container is disposed in contact with the rear surface of the light emitter in a cooling / freezing mechanism.

A blue LED light irradiation cooling / freezing treatment device having a sufficiently high output enables the skin surface to be contact-cooled, and at the same time, the subcutaneous adipose tissue can be softened, dissolved and contracted via the contact cooling surface. The blue LED light irradiation cooling / freezing treatment device can soften or reduce the subcutaneous fat tissue with no burden of fever and skin inflammation and less burden on the epidermis. Efficient fat dissolution and reduction can be achieved by a blue LED light irradiation cooling / freezing treatment device having a fat absorption specific high wavelength. With the blue LED light irradiation and refrigeration treatment device capable of pulse irradiation, overheating during the blue LED light irradiation can be prevented and the occurrence of thermal pain can be prevented. The application can be expanded by blue LED light irradiation and a cryotherapy device by freezing constriction in a thick part of the fat layer and light constriction in a thin part. The blue LED light irradiation and the refrigeration treatment device can be combined with refrigeration constriction and light constriction, so that a large amount of light energy can be input, and high constriction efficiency of adipose tissue can be realized. Blue LED light irradiation having a suction cup and a suction mechanism, and high freezing efficiency for adipose tissue is realized by suctioning the skin in the range of freezing treatment by a freezing treatment device. Blue LED light irradiation with a gel body and Peltier cooler in contact with the skin, or a structure in which a cooling vessel with antifreeze circulation is placed in contact with the back of the light emitter, high cooling efficiency and low temperature reachable by cryotherapy It becomes possible.

It is an external view of the handpiece of a blue LED light irradiator. It is a perspective view of the handpiece of the blue LED light irradiator in which the thermally conductive and translucent gel body is attached to the irradiation unit. It is a perspective view of the handpiece of the blue LED light irradiator that can be cooled and frozen by the antifreeze circulating cooling container. It is a perspective view of the handpiece of a blue LED light irradiator that can be cooled and frozen by a Peltier cooler. It is a perspective view of the handpiece of a blue LED light irradiator equipped with a detachable air suction cup capable of sucking the skin in the freezing range. It is a melt | dissolution photograph of the fat tissue by high output blue LED light under skin surface cooling with respect to excision pig skin tissue. It is the photograph of skin surface reduction | decrease by high output blue LED light under skin surface cooling with respect to excision pig skin tissue. It is a pathological specimen micrograph of the influence of high-power blue LED light under skin surface cooling on the skin tissue of the rat experimental animal back.

The handpiece-type high-power blue LED irradiator has one blue LED light source and a temperature sensor 2 that is a safety mechanism that stops light emission when the temperature reaches a set temperature to prevent skin burns due to heat generated by the light source. Reference numeral 3 denotes a heat transfer mount for transferring light from the light source. The heat sink 4 gradually heats the heat from the light source via the heat transfer mount. Reference numeral 5 denotes an operator's grip handle. Reference numeral 6 denotes a protection tube for a power source of the light source and an electric system of a signal cable of the temperature sensor. 8 is a thermally conductive and translucent gel that can freeze the skin surface to −5 ° C. or lower, and transmits the LED luminous body to the skin, and transmits the cooling of the back surface of the LED luminous body to the skin. 9 is a thin light-transmitting film that partitions the gel body and the skin. Reference numeral 10 denotes a cooling container for antifreeze liquid circulation, and 11 and 12 denote antifreeze liquid circulation hoses. Reference numeral 13 denotes a power source for the light source and an electrical cable for the temperature sensor. Reference numeral 14 denotes a Peltier cooler. Reference numeral 15 denotes a removable air suction cup capable of sucking the skin, and 16 a suction tube thereof. Reference numeral 17 denotes aspirated subcutaneous tissue and skin tissue.

The LED emitter generates an output of 8 W per cm2. The irradiation area has an irradiation surface of 4 × 4 cm 2. The Peltier cooler has a maximum heat absorption amount of 300 W, and has an antifreeze circulating pump, a radiator, and a radiator cooling fan that can cool the LED light emitter to minus 10 degrees C or less. In the case of LED irradiation, the set temperature is 10 ° C., and the time for irradiating a 4 × 4 cm 2 spot is 5 minutes at maximum. In the case of cryotherapy, the detachable air suction pressure is variable and adjusted until the sucked skin surface contacts the gel body in the cup. The set temperature is −7 degrees C., and it is 30 minutes or more per part. Photo 6 shows excised porcine skin tissue irradiated for 1 minute, 3 minutes, and 5 minutes at a temperature setting of 10 ° C. The skin surface was cut from the muscle and the cut surfaces were opened on both sides. The generation of liquefied oil was confirmed at the time of incision. The adipose tissue is solidified and white at normal temperature, but appears gray on the photograph due to the change in the refractive index of light due to dissolution. The width of gray increases in proportion to the irradiation time of 1, 3, 5 minutes, and dissolution occurs to a depth of about 5 mm in 5 minutes. Photo 7 shows the result of reducing the area by irradiating the cut pig skin at a set temperature of 10 ° C. for 5 minutes. A reduction in area of about 10% was observed. Photo 8 shows the result of irradiating rat experimental animal skin at a set temperature of 10 ° C. for 5 minutes. Degeneration and inflammation were not observed. Dermal follicles and sebaceous gland atrophy were observed. The disappearance of hair bulbs in the dermis layer and subcutaneous tissue and the concentration of epidermal cell nuclei were observed. It is speculated that dermal layer follicles, sebaceous gland atrophy and epidermal cell nucleus enrichment are associated with reduction of resected pig skin. The cause of hairball loss is unknown.

According to the present invention, it is possible to soften and dissolve the adipose tissue having different thicknesses while preventing tarmi of the epidermis without causing damage such as inflammatory reaction and heat denaturation. As a result, it is less burdensome and can be widely applied to the face and whole body part. The beauty forming technique of the present invention contributes to the spread of treatment not only in cosmetic surgery but also in cosmetic dermatology.

Claims (10)

Blue LED light irradiation cooling / freezing treatment device with high enough power to soften and dissolve the fat component of subcutaneous adipose tissue via contact cooling surface and contact skin cooling and contract the skin tissue at the same time LED illuminator generating a blue wavelength of 400 to 480 nm in the illuminator of claim 1 2. A temperature control mechanism using pulsed light emission that increases the accuracy of temperature control of a living body in the irradiator of claim 1. The blue LED luminous body having a high output of 1 W or more per unit area in the irradiator according to claim 1 A blue LED light irradiation cooling / freezing treatment function for freezing subcutaneous fat components and contracting fat cells via the light irradiation contact surface of claim 1 A heat-conductive and translucent gel body that can cool and cool the skin surface to body temperature or less in the irradiator according to claim 2, and can freeze the skin surface to -5 degrees C or less. A mechanism for cooling and freezing a gel body in skin contact with an LED light emitter in the irradiator of claim 1 A detachable air suction cup capable of sucking the skin within the range to be cooled and frozen by the blue LED light irradiation cooling / freezing treatment device according to claim 1. 7. The cooling / freezing mechanism according to claim 6, wherein the Peltier cooler is disposed in contact with the back surface of the light emitter. 7. The cooling / freezing mechanism according to claim 6, wherein the antifreeze circulating cooling container is arranged in contact with the rear surface of the light emitter.